Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerSARS-COV-2
Drug Drug
Main interacting RNAs N.A.
Moonlighting functions Metabolic enzyme
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000080824 Gene ID 3320 Accession 5253
Symbol HSP90AA1 Alias EL52;HSPN;LAP2;HSP86;HSPC1;HSPCA;Hsp89;Hsp90;LAP-2;HSP89A;HSP90A;HSP90N;Hsp103;HSPCAL1;HSPCAL4;HEL-S-65p Full Name heat shock protein 90 alpha family class A member 1
Status Confidence Length 58958 bases Strand Minus strand
Position 14 : 102080742 - 102139699 RNA binding domain N.A.
Summary The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
26071189 Regulation and function of the human HSP90AA1 gene. D Abbey Zuehlke 2015-10-01 Gene
33466626 The Taming of Nuclear Factor Erythroid-2-Related Factor-2 (Nrf2) Deglycation by Fructosamine-3-Kinase (FN3K)-Inhibitors-A Novel Strategy to Combat Cancers. M Narasimha Beeraka 2021-01-14 Cancers

Transcripts

Name Transcript ID bp Protein Translation ID
HSP90AA1-201 ENST00000216281 3228 732aa ENSP00000216281
HSP90AA1-202 ENST00000334701 3510 854aa ENSP00000335153
HSP90AA1-204 ENST00000554401 1710 52aa ENSP00000451400
HSP90AA1-207 ENST00000557089 694 No protein -
HSP90AA1-210 ENST00000560130 488 No protein -
HSP90AA1-203 ENST00000553585 581 174aa ENSP00000450712
HSP90AA1-205 ENST00000555662 429 No protein -
HSP90AA1-206 ENST00000556554 552 No protein -
HSP90AA1-208 ENST00000557234 584 80aa ENSP00000452241
HSP90AA1-209 ENST00000558600 595 100aa ENSP00000489370

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
77184Tobacco Use Disorder4E-623942779

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000080824homo_sapiensENSP0000036070994.613387.0166homo_sapiensENSP0000021628193.579286.0656
ENSG00000080824homo_sapiensENSP0000024695753.551132.1023homo_sapiensENSP0000021628151.502730.8743
ENSG00000080824homo_sapiensENSP0000029976761.145744.5828homo_sapiensENSP0000021628167.076548.9071

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000080824homo_sapiensENSP0000021628199.726899.7268nomascus_leucogenysENSNLEP0000002582985.580385.5803
ENSG00000080824homo_sapiensENSP0000021628199.863499.8634pan_paniscusENSPPAP0000003262385.597285.5972
ENSG00000080824homo_sapiensENSP00000216281100100pongo_abeliiENSPPYP0000001705685.714385.7143
ENSG00000080824homo_sapiensENSP0000021628110099.8634pan_troglodytesENSPTRP0000007094685.61485.4971
ENSG00000080824homo_sapiensENSP0000021628115.84715.5738gorilla_gorillaENSGGOP0000002314697.47995.7983
ENSG00000080824homo_sapiensENSP0000021628198.497395.4918ornithorhynchus_anatinusENSOANP0000000913198.362995.3615
ENSG00000080824homo_sapiensENSP0000021628199.043797.6776sarcophilus_harrisiiENSSHAP0000000924199.179297.8112
ENSG00000080824homo_sapiensENSP0000021628143.169441.1202notamacropus_eugeniiENSMEUP0000001059961.718858.7891
ENSG00000080824homo_sapiensENSP0000021628139.480935.5191choloepus_hoffmanniENSCHOP0000001174137.290333.5484
ENSG00000080824homo_sapiensENSP0000021628127.868922.4044dasypus_novemcinctusENSDNOP0000003422372.597958.363
ENSG00000080824homo_sapiensENSP0000021628129.644823.3607echinops_telfairiENSETEP0000001179370.68455.7003
ENSG00000080824homo_sapiensENSP00000216281100100callithrix_jacchusENSCJAP0000005012894.573694.5736
ENSG00000080824homo_sapiensENSP0000021628188.661285.3825cercocebus_atysENSCATP0000000288495.441291.9118
ENSG00000080824homo_sapiensENSP00000216281100100macaca_fascicularisENSMFAP0000003254699.863699.8636
ENSG00000080824homo_sapiensENSP00000216281100100macaca_mulattaENSMMUP0000008072599.863699.8636
ENSG00000080824homo_sapiensENSP00000216281100100macaca_nemestrinaENSMNEP0000002176688.942988.9429
ENSG00000080824homo_sapiensENSP0000021628115.573815.3005macaca_nemestrinaENSMNEP0000000123297.435995.7265
ENSG00000080824homo_sapiensENSP00000216281100100papio_anubisENSPANP0000001324199.863699.8636
ENSG00000080824homo_sapiensENSP0000021628188.251485.5191mandrillus_leucophaeusENSMLEP0000002462895.988193.0163
ENSG00000080824homo_sapiensENSP0000021628161.065660.6557tursiops_truncatusENSTTRP0000000429553.532953.1737
ENSG00000080824homo_sapiensENSP0000021628190.437289.8907vulpes_vulpesENSVVUP0000004036899.849299.2458
ENSG00000080824homo_sapiensENSP0000021628199.863499.5902equus_asinusENSEASP0000500524089.803489.5577
ENSG00000080824homo_sapiensENSP0000021628199.863499.5902capra_hircusENSCHIP0000002565199.727199.4543
ENSG00000080824homo_sapiensENSP0000021628199.590298.9071loxodonta_africanaENSLAFP0000002529499.048998.3696
ENSG00000080824homo_sapiensENSP0000021628110099.4536panthera_leoENSPLOP0000001388599.863699.3179
ENSG00000080824homo_sapiensENSP00000216281100100ailuropoda_melanoleucaENSAMEP00000027930100100
ENSG00000080824homo_sapiensENSP0000021628199.863499.5902bos_indicus_hybridENSBIXP0000501039594.20193.9433
ENSG00000080824homo_sapiensENSP0000021628197.950896.8579oryctolagus_cuniculusENSOCUP0000003654494.466493.4124
ENSG00000080824homo_sapiensENSP0000021628199.863499.5902equus_caballusENSECAP0000002592687.544987.3054
ENSG00000080824homo_sapiensENSP0000021628110099.3169canis_lupus_familiarisENSCAFP0084500764899.863699.1814
ENSG00000080824homo_sapiensENSP0000021628110099.4536panthera_pardusENSPPRP0000000423887.664787.1856
ENSG00000080824homo_sapiensENSP0000021628199.726899.5902marmota_marmota_marmotaENSMMMP0000000398199.590799.4543
ENSG00000080824homo_sapiensENSP0000021628199.726899.4536balaenoptera_musculusENSBMSP0001001016299.726899.4536
ENSG00000080824homo_sapiensENSP0000021628199.863499.4536cavia_porcellusENSCPOP0000000182299.727199.3179
ENSG00000080824homo_sapiensENSP0000021628197.131196.3115felis_catusENSFCAP0000004154994.422393.6255
ENSG00000080824homo_sapiensENSP0000021628110099.4536ursus_americanusENSUAMP0000002381999.863699.3179
ENSG00000080824homo_sapiensENSP0000021628145.218642.4863monodelphis_domesticaENSMODP0000005984494.034188.3523
ENSG00000080824homo_sapiensENSP0000021628199.726899.4536bison_bison_bisonENSBBBP0000001596599.590799.3179
ENSG00000080824homo_sapiensENSP0000021628110099.7268monodon_monocerosENSMMNP0001501826099.863699.5907
ENSG00000080824homo_sapiensENSP0000021628199.180398.7705sus_scrofaENSSSCP0000000274389.189288.8206
ENSG00000080824homo_sapiensENSP0000021628198.497397.9508microcebus_murinusENSMICP0000002873999.861599.3075
ENSG00000080824homo_sapiensENSP0000021628186.065682.1038octodon_degusENSODEP0000001878993.889789.5678
ENSG00000080824homo_sapiensENSP0000021628177.732273.224octodon_degusENSODEP0000002332789.045483.8811
ENSG00000080824homo_sapiensENSP0000021628179.098475.6831octodon_degusENSODEP0000000190192.49288.4984
ENSG00000080824homo_sapiensENSP0000021628116.120215.9836octodon_degusENSODEP0000000343699.159798.3193
ENSG00000080824homo_sapiensENSP0000021628199.453698.7705jaculus_jaculusENSJJAP0000001626899.72699.0411
ENSG00000080824homo_sapiensENSP0000021628180.191375.5464jaculus_jaculusENSJJAP0000002258889.209784.0426
ENSG00000080824homo_sapiensENSP0000021628199.863499.5902ovis_aries_rambouilletENSOARP0002001598099.727199.4543
ENSG00000080824homo_sapiensENSP0000021628110099.4536ursus_maritimusENSUMAP0000000284199.863699.3179
ENSG00000080824homo_sapiensENSP0000021628110099.7268delphinapterus_leucasENSDLEP0000000207499.863699.5907
ENSG00000080824homo_sapiensENSP0000021628115.84715.7104physeter_catodonENSPCTP0000501532197.47996.6387
ENSG00000080824homo_sapiensENSP0000021628110099.7268physeter_catodonENSPCTP0000503073899.863699.5907
ENSG00000080824homo_sapiensENSP0000021628187.295186.7486mus_caroliMGP_CAROLIEiJ_P003336499.68899.064
ENSG00000080824homo_sapiensENSP0000021628199.863499.1803mus_musculusENSMUSP0000009192199.727199.045
ENSG00000080824homo_sapiensENSP0000021628199.863499.3169dipodomys_ordiiENSDORP0000000521099.727199.1814
ENSG00000080824homo_sapiensENSP0000021628122.404422.4044mustela_putorius_furoENSMPUP00000002072100100
ENSG00000080824homo_sapiensENSP0000021628199.863499.8634aotus_nancymaaeENSANAP0000003906192.531692.5316
ENSG00000080824homo_sapiensENSP0000021628115.983615.9836aotus_nancymaaeENSANAP0000000337098.319398.3193
ENSG00000080824homo_sapiensENSP0000021628169.945469.1257aotus_nancymaaeENSANAP0000000351596.240695.1128
ENSG00000080824homo_sapiensENSP0000021628142.759641.9399aotus_nancymaaeENSANAP0000000600995.136893.3131
ENSG00000080824homo_sapiensENSP0000021628145.628445.6284saimiri_boliviensis_boliviensisENSSBOP0000002595199.701599.7015
ENSG00000080824homo_sapiensENSP0000021628195.08294.2623saimiri_boliviensis_boliviensisENSSBOP0000000718798.723497.8723
ENSG00000080824homo_sapiensENSP0000021628152.732252.7322chlorocebus_sabaeusENSCSAP0000000648399.741699.7416
ENSG00000080824homo_sapiensENSP0000021628171.857971.5847tupaia_belangeriENSTBEP0000000286162.248562.0118
ENSG00000080824homo_sapiensENSP0000021628110099.7268phocoena_sinusENSPSNP0000001403699.863699.5907
ENSG00000080824homo_sapiensENSP0000021628110099.7268camelus_dromedariusENSCDRP0000500779196.315896.0526
ENSG00000080824homo_sapiensENSP0000021628168.715864.6175carlito_syrichtaENSTSYP0000003184282.866677.9242
ENSG00000080824homo_sapiensENSP0000021628110099.7268carlito_syrichtaENSTSYP0000001094190.036989.7909
ENSG00000080824homo_sapiensENSP0000021628193.442691.8033carlito_syrichtaENSTSYP0000002251897.994396.2751
ENSG00000080824homo_sapiensENSP0000021628110099.4536panthera_tigris_altaicaENSPTIP0000000883799.863699.3179
ENSG00000080824homo_sapiensENSP0000021628199.863499.3169rattus_norvegicusENSRNOP0000007571599.727199.1814
ENSG00000080824homo_sapiensENSP0000021628199.863499.5902prolemur_simusENSPSMP0000003325599.727199.4543
ENSG00000080824homo_sapiensENSP0000021628114.480914.071prolemur_simusENSPSMP0000000366192.982590.3509
ENSG00000080824homo_sapiensENSP0000021628110.38259.69945prolemur_simusENSPSMP000000317788074.7368
ENSG00000080824homo_sapiensENSP0000021628173.907170.3552microtus_ochrogasterENSMOCP0000002353190.771886.4094
ENSG00000080824homo_sapiensENSP0000021628147.54146.9945sorex_araneusENSSARP0000001093781.118980.1865
ENSG00000080824homo_sapiensENSP0000021628187.841585.929peromyscus_maniculatus_bairdiiENSPEMP0000000009990.691188.7165
ENSG00000080824homo_sapiensENSP0000021628115.710415.5738peromyscus_maniculatus_bairdiiENSPEMP0000003181796.638795.7983
ENSG00000080824homo_sapiensENSP0000021628188.114886.8852bos_mutusENSBMUP0000002367397.138695.7831
ENSG00000080824homo_sapiensENSP0000021628116.120215.847bos_mutusENSBMUP0000001988399.159797.479
ENSG00000080824homo_sapiensENSP0000021628199.316998.224mus_spicilegusENSMSIP0000000500199.181498.09
ENSG00000080824homo_sapiensENSP0000021628188.661287.4317mus_spicilegusENSMSIP0000003287998.932997.561
ENSG00000080824homo_sapiensENSP0000021628199.863499.0437mus_spicilegusENSMSIP0000000913299.727198.9086
ENSG00000080824homo_sapiensENSP0000021628197.131196.7213cricetulus_griseus_chok1gshdENSCGRP0000101299399.719599.2987
ENSG00000080824homo_sapiensENSP0000021628197.131196.4481pteropus_vampyrusENSPVAP0000001677887.346486.7322
ENSG00000080824homo_sapiensENSP0000021628197.404496.9945myotis_lucifugusENSMLUP0000001214099.58199.162
ENSG00000080824homo_sapiensENSP0000021628111.20229.28962vombatus_ursinusENSVURP0001001295474.545561.8182
ENSG00000080824homo_sapiensENSP0000021628199.590298.9071rhinolophus_ferrumequinumENSRFEP0001000023195.418894.7644
ENSG00000080824homo_sapiensENSP0000021628199.726899.0437rhinolophus_ferrumequinumENSRFEP0001000560399.590798.9086
ENSG00000080824homo_sapiensENSP0000021628115.573815.0273neovison_visonENSNVIP0000002316895.798392.437
ENSG00000080824homo_sapiensENSP0000021628115.437214.6175neovison_visonENSNVIP0000002318181.29576.9784
ENSG00000080824homo_sapiensENSP0000021628141.120240.3005bos_taurusENSBTAP0000006621698.045696.0912
ENSG00000080824homo_sapiensENSP0000021628199.726899.1803heterocephalus_glaber_femaleENSHGLP0000001503797.986697.4497
ENSG00000080824homo_sapiensENSP0000021628193.442692.8962rhinopithecus_bietiENSRBIP0000003323899.708599.1254
ENSG00000080824homo_sapiensENSP0000021628110099.3169canis_lupus_dingoENSCAFP0002001134099.863699.1814
ENSG00000080824homo_sapiensENSP0000021628199.863499.5902sciurus_vulgarisENSSVLP0000501878999.727199.4543
ENSG00000080824homo_sapiensENSP0000021628199.180397.8142phascolarctos_cinereusENSPCIP0000003396899.31697.948
ENSG00000080824homo_sapiensENSP0000021628174.316972.8142procavia_capensisENSPCAP0000000285965.700564.372
ENSG00000080824homo_sapiensENSP0000021628199.863499.1803nannospalax_galiliENSNGAP0000001094999.727199.045
ENSG00000080824homo_sapiensENSP0000021628198.087497.8142bos_grunniensENSBGRP0000002386599.722299.4444
ENSG00000080824homo_sapiensENSP0000021628199.726899.3169chinchilla_lanigeraENSCLAP0000000657999.590799.1814
ENSG00000080824homo_sapiensENSP0000021628199.863499.5902cervus_hanglu_yarkandensisENSCHYP0000002177299.727199.4543
ENSG00000080824homo_sapiensENSP0000021628196.721396.4481cervus_hanglu_yarkandensisENSCHYP0000001616499.718399.4366
ENSG00000080824homo_sapiensENSP0000021628199.726899.4536catagonus_wagneriENSCWAP0000000771499.590799.3179
ENSG00000080824homo_sapiensENSP0000021628199.863499.7268ictidomys_tridecemlineatusENSSTOP0000000865899.727199.5907
ENSG00000080824homo_sapiensENSP0000021628157.240450.6831otolemur_garnettiiENSOGAP0000000463682.64373.1755
ENSG00000080824homo_sapiensENSP0000021628115.710415.7104cebus_imitatorENSCCAP0000000300597.457697.4576
ENSG00000080824homo_sapiensENSP0000021628198.497398.3607cebus_imitatorENSCCAP0000003314799.861599.723
ENSG00000080824homo_sapiensENSP0000021628114.890714.071cebus_imitatorENSCCAP0000000335497.321491.9643
ENSG00000080824homo_sapiensENSP0000021628113.797813.1148urocitellus_parryiiENSUPAP0001000548684.166780
ENSG00000080824homo_sapiensENSP0000021628199.863499.3169moschus_moschiferusENSMMSP0000001470199.727199.1814
ENSG00000080824homo_sapiensENSP0000021628186.065684.0164rhinopithecus_roxellanaENSRROP0000002345693.889791.6543
ENSG00000080824homo_sapiensENSP0000021628188.934488.7978rhinopithecus_roxellanaENSRROP0000003493199.086898.9345
ENSG00000080824homo_sapiensENSP0000021628189.890788.7978rhinopithecus_roxellanaENSRROP0000001198897.626196.4392
ENSG00000080824homo_sapiensENSP0000021628178.825177.8689mus_pahariMGP_PahariEiJ_P008347998.464297.2696
ENSG00000080824homo_sapiensENSP0000021628114.207713.7978propithecus_coquereliENSPCOP0000001856692.035489.3805
ENSG00000080824homo_sapiensENSP0000021628186.338883.7432propithecus_coquereliENSPCOP0000001793092.941290.1471
ENSG00000080824homo_sapiensENSP0000021628185.655775caenorhabditis_elegansC47E8.5.289.316278.2051
ENSG00000080824homo_sapiensENSP0000021628187.978177.5956drosophila_melanogasterFBpp030509589.818779.219
ENSG00000080824homo_sapiensENSP0000021628177.45968.0328ciona_intestinalisENSCINP0000002341685.135174.7748
ENSG00000080824homo_sapiensENSP0000021628135.92932.7869petromyzon_marinusENSPMAP0000000016390.689782.7586
ENSG00000080824homo_sapiensENSP0000021628193.989185.6557eptatretus_burgeriENSEBUP0000000425993.989185.6557
ENSG00000080824homo_sapiensENSP0000021628111.20229.01639callorhinchus_miliiENSCMIP0000003093156.164445.2055
ENSG00000080824homo_sapiensENSP0000021628192.486385.3825latimeria_chalumnaeENSLACP0000000081892.739785.6164
ENSG00000080824homo_sapiensENSP0000021628174.453670.9016lepisosteus_oculatusENSLOCP0000000008295.279790.7343
ENSG00000080824homo_sapiensENSP0000021628193.989187.7049lepisosteus_oculatusENSLOCP0000001415193.989187.7049
ENSG00000080824homo_sapiensENSP000002162818.743178.06011clupea_harengusENSCHAP0000003255285.333378.6667
ENSG00000080824homo_sapiensENSP0000021628195.901691.2568danio_rerioENSDARP0000002606595.640391.0082
ENSG00000080824homo_sapiensENSP0000021628193.169485.1093danio_rerioENSDARP0000002230294.06985.931
ENSG00000080824homo_sapiensENSP0000021628192.622985.929carassius_auratusENSCARP0000008196090.159683.6436
ENSG00000080824homo_sapiensENSP0000021628195.355290.0273carassius_auratusENSCARP0000012225792.572987.4005
ENSG00000080824homo_sapiensENSP0000021628194.945490.3005carassius_auratusENSCARP0000009261892.420287.8989
ENSG00000080824homo_sapiensENSP0000021628195.491890.9836astyanax_mexicanusENSAMXP0000002119495.622491.1081
ENSG00000080824homo_sapiensENSP0000021628194.945490.0273ictalurus_punctatusENSIPUP0000003310795.598490.6465
ENSG00000080824homo_sapiensENSP0000021628192.486384.8361ictalurus_punctatusENSIPUP0000003307393.637685.8921
ENSG00000080824homo_sapiensENSP0000021628194.535588.7978esox_luciusENSELUP0000006483492.637287.0147
ENSG00000080824homo_sapiensENSP0000021628192.622986.612electrophorus_electricusENSEEEP0000002503793.775987.6902
ENSG00000080824homo_sapiensENSP0000021628195.355290.1639electrophorus_electricusENSEEEP0000002392992.819187.766
ENSG00000080824homo_sapiensENSP0000021628194.262387.0219oncorhynchus_kisutchENSOKIP0000511343287.674780.9403
ENSG00000080824homo_sapiensENSP0000021628194.262386.7486oncorhynchus_kisutchENSOKIP0000502288590.670283.4428
ENSG00000080824homo_sapiensENSP0000021628194.535587.1585oncorhynchus_mykissENSOMYP0000000659991.655684.5033
ENSG00000080824homo_sapiensENSP0000021628194.125786.8852oncorhynchus_mykissENSOMYP0000008259587.325780.6084
ENSG00000080824homo_sapiensENSP0000021628190.437282.5137salmo_salarENSSSAP0000007584990.809382.8532
ENSG00000080824homo_sapiensENSP0000021628194.398987.5683salmo_salarENSSSAP0000007545290.921184.3421
ENSG00000080824homo_sapiensENSP0000021628194.262386.4754salmo_salarENSSSAP0000003866869.486463.7462
ENSG00000080824homo_sapiensENSP0000021628191.393483.1967salmo_truttaENSSTUP0000007532185.331677.6786
ENSG00000080824homo_sapiensENSP0000021628194.535586.7486salmo_truttaENSSTUP0000000352490.104282.6823
ENSG00000080824homo_sapiensENSP0000021628191.393484.4262gadus_morhuaENSGMOP0000004336489.919483.0645
ENSG00000080824homo_sapiensENSP0000021628190.573882.2404gadus_morhuaENSGMOP0000005845787.236879.2105
ENSG00000080824homo_sapiensENSP0000021628195.76591.2568fundulus_heteroclitusENSFHEP0000001664795.89691.3817
ENSG00000080824homo_sapiensENSP0000021628159.836156.0109poecilia_reticulataENSPREP0000002097388.306482.6613
ENSG00000080824homo_sapiensENSP0000021628192.213186.2022poecilia_reticulataENSPREP0000002094688.005282.2686
ENSG00000080824homo_sapiensENSP0000021628192.076586.2022xiphophorus_maculatusENSXMAP0000000833893.093987.1547
ENSG00000080824homo_sapiensENSP0000021628195.491891.2568xiphophorus_maculatusENSXMAP0000000833295.361591.1323
ENSG00000080824homo_sapiensENSP0000021628195.491891.1202oryzias_latipesENSORLP0000001490095.753491.3699
ENSG00000080824homo_sapiensENSP0000021628191.666784.0164cyclopterus_lumpusENSCLMP0000503826486.469179.2526
ENSG00000080824homo_sapiensENSP0000021628192.213186.4754oreochromis_niloticusENSONIP0000007004187.662382.2078
ENSG00000080824homo_sapiensENSP0000021628192.622986.4754haplochromis_burtoniENSHBUP0000001670393.646487.4309
ENSG00000080824homo_sapiensENSP0000021628196.038391.3934haplochromis_burtoniENSHBUP0000002010096.433591.7695
ENSG00000080824homo_sapiensENSP000002162816.420765.60109astatotilapia_callipteraENSACLP0000000163078.333368.3333
ENSG00000080824homo_sapiensENSP0000021628196.311590.9836sparus_aurataENSSAUP0001006427791.439786.3813
ENSG00000080824homo_sapiensENSP0000021628196.038390.9836lates_calcariferENSLCAP0001004420185.627381.1206
ENSG00000080824homo_sapiensENSP0000021628196.721392.7596xenopus_tropicalisENSXETP0000006449997.119393.1413
ENSG00000080824homo_sapiensENSP0000021628197.814296.1749chrysemys_picta_belliiENSCPBP0000002768898.351696.7033
ENSG00000080824homo_sapiensENSP0000021628111.202211.0656sphenodon_punctatusENSSPUP0000001216110098.7805
ENSG00000080824homo_sapiensENSP0000021628197.814296.3115crocodylus_porosusENSCPRP0000501899391.560190.1535
ENSG00000080824homo_sapiensENSP0000021628197.814296.1749laticauda_laticaudataENSLLTP0000000012498.351696.7033
ENSG00000080824homo_sapiensENSP0000021628198.087496.4481notechis_scutatusENSNSUP0000001507598.626496.978
ENSG00000080824homo_sapiensENSP0000021628197.950896.1749pseudonaja_textilisENSPTXP0000002142498.48996.7033
ENSG00000080824homo_sapiensENSP0000021628148.770548.224anas_platyrhynchos_platyrhynchosENSAPLP0000001725398.618897.5138
ENSG00000080824homo_sapiensENSP0000021628148.633948.0874anas_platyrhynchos_platyrhynchosENSAPLP0000002527295.187294.1176
ENSG00000080824homo_sapiensENSP0000021628197.404495.6284gallus_gallusENSGALP0001002366197.13995.3678
ENSG00000080824homo_sapiensENSP0000021628197.814296.0383meleagris_gallopavoENSMGAP0000001411698.351696.5659
ENSG00000080824homo_sapiensENSP0000021628197.814296.4481serinus_canariaENSSCAP0000000884995.978694.6381
ENSG00000080824homo_sapiensENSP0000021628197.950896.4481parus_majorENSPMJP0000002343898.48996.978
ENSG00000080824homo_sapiensENSP0000021628197.814295.9016anolis_carolinensisENSACAP0000000015698.351696.4286
ENSG00000080824homo_sapiensENSP0000021628196.038391.2568neolamprologus_brichardiENSNBRP0000002876496.433591.6324
ENSG00000080824homo_sapiensENSP0000021628192.622986.4754neolamprologus_brichardiENSNBRP0000002871893.646487.4309
ENSG00000080824homo_sapiensENSP0000021628198.087496.4481naja_najaENSNNAP0000000181698.626496.978
ENSG00000080824homo_sapiensENSP0000021628197.814295.6284podarcis_muralisENSPMRP0000000065698.351696.1538
ENSG00000080824homo_sapiensENSP0000021628197.677696.1749geospiza_fortisENSGFOP0000001018695.844594.37
ENSG00000080824homo_sapiensENSP0000021628148.360741.9399taeniopygia_guttataENSTGUP0000003789279.909769.3002
ENSG00000080824homo_sapiensENSP0000021628196.584792.3497erpetoichthys_calabaricusENSECRP0000003055096.452992.2237
ENSG00000080824homo_sapiensENSP0000021628192.213186.3388kryptolebias_marmoratusENSKMAP0000002647393.23287.2928
ENSG00000080824homo_sapiensENSP0000021628196.311591.9399kryptolebias_marmoratusENSKMAP0000002641496.311591.9399
ENSG00000080824homo_sapiensENSP0000021628131.010928.0055salvator_merianaeENSSMRP0000002678083.455975.3676
ENSG00000080824homo_sapiensENSP0000021628192.213187.1585oryzias_javanicusENSOJAP0000004103286.206981.4815
ENSG00000080824homo_sapiensENSP0000021628190.437283.6066amphilophus_citrinellusENSACIP0000000350285.751379.2746
ENSG00000080824homo_sapiensENSP0000021628196.174991.3934amphilophus_citrinellusENSACIP0000000277196.836392.022
ENSG00000080824homo_sapiensENSP0000021628195.08290.4372dicentrarchus_labraxENSDLAP0000500266380.462476.5318
ENSG00000080824homo_sapiensENSP0000021628192.213186.0656amphiprion_perculaENSAPEP0000003268693.23287.0166
ENSG00000080824homo_sapiensENSP0000021628196.448191.2568amphiprion_perculaENSAPEP0000003267296.84591.6324
ENSG00000080824homo_sapiensENSP0000021628191.803386.612oryzias_sinensisENSOSIP0000003750991.67886.4939
ENSG00000080824homo_sapiensENSP0000021628197.814296.1749pelodiscus_sinensisENSPSIP0000002028698.351696.7033
ENSG00000080824homo_sapiensENSP0000021628129.781428.0055gopherus_evgoodeiENSGEVP0000500445897.321491.5179
ENSG00000080824homo_sapiensENSP0000021628113.38813.2514gopherus_evgoodeiENSGEVP0000500446689.090988.1818
ENSG00000080824homo_sapiensENSP0000021628197.814296.1749chelonoidis_abingdoniiENSCABP0000001038298.351696.7033
ENSG00000080824homo_sapiensENSP0000021628196.311591.2568seriola_dumeriliENSSDUP0000001336596.575391.5069
ENSG00000080824homo_sapiensENSP0000021628190.84784.5628seriola_dumeriliENSSDUP0000001330489.142182.9759
ENSG00000080824homo_sapiensENSP0000021628195.355288.6612cottoperca_gobioENSCGOP0000005279888.578782.3604
ENSG00000080824homo_sapiensENSP0000021628197.950896.3115struthio_camelus_australisENSSCUP0000001261393.116991.5584
ENSG00000080824homo_sapiensENSP0000021628197.814296.0383anser_brachyrhynchusENSABRP0000001250994.334692.6219
ENSG00000080824homo_sapiensENSP0000021628192.213187.0219gasterosteus_aculeatusENSGACP0000001705294.011188.7187
ENSG00000080824homo_sapiensENSP0000021628191.393484.6995gasterosteus_aculeatusENSGACP0000001702092.531185.7538
ENSG00000080824homo_sapiensENSP0000021628195.628490.7104cynoglossus_semilaevisENSCSEP0000000071396.153891.2088
ENSG00000080824homo_sapiensENSP0000021628192.076585.6557cynoglossus_semilaevisENSCSEP0000000257093.093986.6022
ENSG00000080824homo_sapiensENSP0000021628195.76591.6667poecilia_formosaENSPFOP0000001526595.634491.5416
ENSG00000080824homo_sapiensENSP0000021628192.076586.3388poecilia_formosaENSPFOP0000001532793.093987.2928
ENSG00000080824homo_sapiensENSP0000021628196.038390.4372myripristis_murdjanENSMMDP0000501197691.298785.974
ENSG00000080824homo_sapiensENSP0000021628192.486385.6557myripristis_murdjanENSMMDP0000500811092.994586.1264
ENSG00000080824homo_sapiensENSP0000021628190.163984.2896sander_luciopercaENSSLUP0000000325186.956581.2912
ENSG00000080824homo_sapiensENSP0000021628197.814296.1749strigops_habroptilaENSSHBP0000501204398.351696.7033
ENSG00000080824homo_sapiensENSP0000021628196.448191.2568amphiprion_ocellarisENSAOCP0000003197496.84591.6324
ENSG00000080824homo_sapiensENSP0000021628192.213186.0656amphiprion_ocellarisENSAOCP0000003199093.23287.0166
ENSG00000080824homo_sapiensENSP0000021628193.715892.2131terrapene_carolina_triunguisENSTMTP0000002184898.847397.2622
ENSG00000080824homo_sapiensENSP0000021628194.535587.1585hucho_huchoENSHHUP0000008812793.640186.3329
ENSG00000080824homo_sapiensENSP0000021628193.989186.3388hucho_huchoENSHHUP0000003652893.098885.521
ENSG00000080824homo_sapiensENSP0000021628190.027382.1038hucho_huchoENSHHUP0000008760585.919278.3572
ENSG00000080824homo_sapiensENSP0000021628192.349786.2022betta_splendensENSBSLP0000004047092.476186.3201
ENSG00000080824homo_sapiensENSP0000021628164.617559.8361pygocentrus_nattereriENSPNAP0000003252893.110286.2205
ENSG00000080824homo_sapiensENSP0000021628195.355291.1202pygocentrus_nattereriENSPNAP0000003258795.616491.3699
ENSG00000080824homo_sapiensENSP0000021628196.584791.2568anabas_testudineusENSATEP0000004739889.380584.4501
ENSG00000080824homo_sapiensENSP0000021628188.934478.5519ciona_savignyiENSCSAVP0000000472090.291379.7503
ENSG00000080824homo_sapiensENSP0000021628177.049261.8852saccharomyces_cerevisiaeYMR186W8064.2553
ENSG00000080824homo_sapiensENSP0000021628176.912662.1585saccharomyces_cerevisiaeYPL240C79.407664.1749
ENSG00000080824homo_sapiensENSP0000021628196.311591.2568seriola_lalandi_dorsalisENSSLDP0000000083596.575391.5069
ENSG00000080824homo_sapiensENSP0000021628196.038391.2568labrus_bergyltaENSLBEP0000003190295.516390.7609
ENSG00000080824homo_sapiensENSP0000021628191.803384.5628labrus_bergyltaENSLBEP0000003183493.074885.7341
ENSG00000080824homo_sapiensENSP000002162817.103835.7377pundamilia_nyerereiENSPNYP0000002154971.232957.5342
ENSG00000080824homo_sapiensENSP0000021628190.437284.4262mastacembelus_armatusENSMAMP0000006237586.197980.4688
ENSG00000080824homo_sapiensENSP0000021628191.939985.6557stegastes_partitusENSSPAP0000000025692.955886.6022
ENSG00000080824homo_sapiensENSP0000021628196.448191.5301stegastes_partitusENSSPAP0000002915396.84591.9067
ENSG00000080824homo_sapiensENSP0000021628113.38811.8852oncorhynchus_tshawytschaENSOTSP0000501911385.964976.3158
ENSG00000080824homo_sapiensENSP0000021628196.448191.3934acanthochromis_polyacanthusENSAPOP0000001664696.97891.8956
ENSG00000080824homo_sapiensENSP0000021628192.213186.3388acanthochromis_polyacanthusENSAPOP0000003206793.23287.2928
ENSG00000080824homo_sapiensENSP0000021628194.945493.1694aquila_chrysaetos_chrysaetosENSACCP0002000109193.41491.6667
ENSG00000080824homo_sapiensENSP0000021628190.300584.9727nothobranchius_furzeriENSNFUP0001502357389.566484.2818
ENSG00000080824homo_sapiensENSP0000021628196.038391.3934nothobranchius_furzeriENSNFUP0001502413992.588.0263
ENSG00000080824homo_sapiensENSP000002162817.650277.10383cyprinodon_variegatusENSCVAP0000001571469.135864.1975
ENSG00000080824homo_sapiensENSP0000021628195.628490.1639denticeps_clupeoidesENSDCDP0000003995491.62386.3874
ENSG00000080824homo_sapiensENSP0000021628195.76591.1202larimichthys_croceaENSLCRP0000500291692.847788.3444
ENSG00000080824homo_sapiensENSP0000021628193.30686.612takifugu_rubripesENSTRUP0000006448194.206987.4483
ENSG00000080824homo_sapiensENSP0000021628197.950896.4481ficedula_albicollisENSFALP0000000285598.48996.978
ENSG00000080824homo_sapiensENSP0000021628188.251481.9672hippocampus_comesENSHCOP0000002492393.487786.8307
ENSG00000080824homo_sapiensENSP0000021628191.803385.7924hippocampus_comesENSHCOP0000001171692.689786.6207
ENSG00000080824homo_sapiensENSP0000021628194.808790.7104cyprinus_carpio_carpioENSCCRP0000014293788.974485.1282
ENSG00000080824homo_sapiensENSP0000021628191.939987.2951cyprinus_carpio_carpioENSCCRP0000017356495.190990.3819
ENSG00000080824homo_sapiensENSP0000021628189.07182.3771cyprinus_carpio_carpioENSCCRP0000013658992.877585.8974
ENSG00000080824homo_sapiensENSP0000021628197.54195.9016coturnix_japonicaENSCJPP0000500249598.076996.4286
ENSG00000080824homo_sapiensENSP0000021628195.76591.6667poecilia_latipinnaENSPLAP0000002529095.634491.5416
ENSG00000080824homo_sapiensENSP0000021628192.076586.3388poecilia_latipinnaENSPLAP0000000939987.874882.399
ENSG00000080824homo_sapiensENSP0000021628114.207713.2514sinocyclocheilus_grahamiENSSGRP0000001281590.434884.3478
ENSG00000080824homo_sapiensENSP0000021628114.207713.2514sinocyclocheilus_grahamiENSSGRP0000001281390.434884.3478
ENSG00000080824homo_sapiensENSP0000021628196.038391.3934maylandia_zebraENSMZEP0000501643096.433591.7695
ENSG00000080824homo_sapiensENSP0000021628114.480913.2514maylandia_zebraENSMZEP0000501644089.075681.5126
ENSG00000080824homo_sapiensENSP0000021628189.617584.0164tetraodon_nigroviridisENSTNIP0000001390594.797788.8728
ENSG00000080824homo_sapiensENSP0000021628114.344312.5683paramormyrops_kingsleyaeENSPKIP0000000268790.517279.3103
ENSG00000080824homo_sapiensENSP0000021628195.628490.847scleropages_formosusENSSFOP0001504653695.628490.847
ENSG00000080824homo_sapiensENSP0000021628196.038391.2568scleropages_formosusENSSFOP0001502863594.362489.6644
ENSG00000080824homo_sapiensENSP0000021628193.169485.6557leptobrachium_leishanenseENSLLEP0000002953992.915585.4223
ENSG00000080824homo_sapiensENSP0000021628195.628490.3005scophthalmus_maximusENSSMAP0000006366692.105386.9737
ENSG00000080824homo_sapiensENSP0000021628187.021980.4645scophthalmus_maximusENSSMAP0000004218389.215782.493
ENSG00000080824homo_sapiensENSP0000021628195.901691.3934oryzias_melastigmaENSOMEP0000002435695.770891.2688

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0001764involved_in neuron migration1IEAHomo_sapiens(9606)Process
GO:0001934involved_in positive regulation of protein phosphorylation1IDAHomo_sapiens(9606)Process
GO:0002134enables UTP binding1IEAHomo_sapiens(9606)Function
GO:0002135enables CTP binding1IEAHomo_sapiens(9606)Function
GO:0002218involved_in activation of innate immune response1IDAHomo_sapiens(9606)Process
GO:0002230involved_in positive regulation of defense response to virus by host1IDAHomo_sapiens(9606)Process
GO:0003009involved_in skeletal muscle contraction1IEAHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003729enables mRNA binding1IEAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding2IBA,IDAHomo_sapiens(9606)Function
GO:0005525enables GTP binding1IEAHomo_sapiens(9606)Function
GO:0005576located_in extracellular region1TASHomo_sapiens(9606)Component
GO:0005634located_in nucleus3HDA,IBA,ISSHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm2IDA,ISSHomo_sapiens(9606)Component
GO:0005739located_in mitochondrion1IDAHomo_sapiens(9606)Component
GO:0005829is_active_in cytosol4IBA,IDA,NAS,TASHomo_sapiens(9606)Component
GO:0005886is_active_in plasma membrane2IBA,TASHomo_sapiens(9606)Component
GO:0006457involved_in protein folding1IBAHomo_sapiens(9606)Process
GO:0006839involved_in mitochondrial transport1TASHomo_sapiens(9606)Process
GO:0006986involved_in response to unfolded protein1NASHomo_sapiens(9606)Process
GO:0007004involved_in telomere maintenance via telomerase1IDAHomo_sapiens(9606)Process
GO:0009408involved_in response to heat1ISSHomo_sapiens(9606)Process
GO:0009409involved_in response to cold1ISSHomo_sapiens(9606)Process
GO:0009410involved_in response to xenobiotic stimulus1IEAHomo_sapiens(9606)Process
GO:0009651involved_in response to salt stress1IEAHomo_sapiens(9606)Process
GO:0009986located_in cell surface1IEAHomo_sapiens(9606)Component
GO:0010592involved_in positive regulation of lamellipodium assembly1IEAHomo_sapiens(9606)Process
GO:0010659involved_in cardiac muscle cell apoptotic process1IEAHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0016323located_in basolateral plasma membrane1IEAHomo_sapiens(9606)Component
GO:0016324located_in apical plasma membrane1IEAHomo_sapiens(9606)Component
GO:0016887enables ATP hydrolysis activity2IDA,TASHomo_sapiens(9606)Function
GO:0017098enables sulfonylurea receptor binding1IEAHomo_sapiens(9606)Function
GO:0019903enables protein phosphatase binding1IEAHomo_sapiens(9606)Function
GO:0021955involved_in central nervous system neuron axonogenesis1ISSHomo_sapiens(9606)Process
GO:0023026enables MHC class II protein complex binding1HDAHomo_sapiens(9606)Function
GO:0030010involved_in establishment of cell polarity1ISSHomo_sapiens(9606)Process
GO:0030235enables nitric-oxide synthase regulator activity1IDAHomo_sapiens(9606)Function
GO:0030911enables TPR domain binding2IDA,TASHomo_sapiens(9606)Function
GO:0031396involved_in regulation of protein ubiquitination1IDAHomo_sapiens(9606)Process
GO:0031526located_in brush border membrane1IEAHomo_sapiens(9606)Component
GO:0031625enables ubiquitin protein ligase binding1IPIHomo_sapiens(9606)Function
GO:0032273involved_in positive regulation of protein polymerization1IDAHomo_sapiens(9606)Process
GO:0032564enables dATP binding1IEAHomo_sapiens(9606)Function
GO:0032728involved_in positive regulation of interferon-beta production1IDAHomo_sapiens(9606)Process
GO:0032880involved_in regulation of protein localization1ISSHomo_sapiens(9606)Process
GO:0032991part_of protein-containing complex2IBA,IDAHomo_sapiens(9606)Component
GO:0033138involved_in positive regulation of peptidyl-serine phosphorylation1ISSHomo_sapiens(9606)Process
GO:0034605involved_in cellular response to heat1IBAHomo_sapiens(9606)Process
GO:0034774located_in secretory granule lumen1TASHomo_sapiens(9606)Component
GO:0042026involved_in protein refolding1TASHomo_sapiens(9606)Process
GO:0042220involved_in response to cocaine1IEAHomo_sapiens(9606)Process
GO:0042307involved_in positive regulation of protein import into nucleus1IEAHomo_sapiens(9606)Process
GO:0042470located_in melanosome1IEAHomo_sapiens(9606)Component
GO:0042802enables identical protein binding2IDA,IPIHomo_sapiens(9606)Function
GO:0042803enables protein homodimerization activity1IDAHomo_sapiens(9606)Function
GO:0042826enables histone deacetylase binding1IPIHomo_sapiens(9606)Function
GO:0042981involved_in regulation of apoptotic process1IDAHomo_sapiens(9606)Process
GO:0043025is_active_in neuronal cell body2IBA,ISSHomo_sapiens(9606)Component
GO:0043202located_in lysosomal lumen1TASHomo_sapiens(9606)Component
GO:0043209is_active_in myelin sheath1IBAHomo_sapiens(9606)Component
GO:0043254involved_in regulation of protein-containing complex assembly1NASHomo_sapiens(9606)Process
GO:0043335involved_in protein unfolding1NASHomo_sapiens(9606)Process
GO:0043627involved_in response to estrogen1IEAHomo_sapiens(9606)Process
GO:0044294located_in dendritic growth cone1ISSHomo_sapiens(9606)Component
GO:0044295located_in axonal growth cone1ISSHomo_sapiens(9606)Component
GO:0044325enables transmembrane transporter binding1IEAHomo_sapiens(9606)Function
GO:0045040involved_in protein insertion into mitochondrial outer membrane1IDAHomo_sapiens(9606)Process
GO:0045429involved_in positive regulation of nitric oxide biosynthetic process1ISSHomo_sapiens(9606)Process
GO:0045732involved_in positive regulation of protein catabolic process1IGIHomo_sapiens(9606)Process
GO:0045793involved_in positive regulation of cell size1IEAHomo_sapiens(9606)Process
GO:0046677involved_in response to antibiotic1ISSHomo_sapiens(9606)Process
GO:0048156enables tau protein binding1IPIHomo_sapiens(9606)Function
GO:0048471is_active_in perinuclear region of cytoplasm2IBA,ISSHomo_sapiens(9606)Component
GO:0048675involved_in axon extension1ISSHomo_sapiens(9606)Process
GO:0050821involved_in protein stabilization2IBA,IMPHomo_sapiens(9606)Process
GO:0051020enables GTPase binding1IPIHomo_sapiens(9606)Function
GO:0051022enables Rho GDP-dissociation inhibitor binding1IEAHomo_sapiens(9606)Function
GO:0051082enables unfolded protein binding1IBAHomo_sapiens(9606)Function
GO:0051131involved_in chaperone-mediated protein complex assembly1IDAHomo_sapiens(9606)Process
GO:0051897involved_in positive regulation of protein kinase B signaling1ISSHomo_sapiens(9606)Process
GO:0051973involved_in positive regulation of telomerase activity1IDAHomo_sapiens(9606)Process
GO:0060452involved_in positive regulation of cardiac muscle contraction1IEAHomo_sapiens(9606)Process
GO:0061684involved_in chaperone-mediated autophagy1TASHomo_sapiens(9606)Process
GO:0062023located_in collagen-containing extracellular matrix1IEAHomo_sapiens(9606)Component
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component
GO:0070182enables DNA polymerase binding1IPIHomo_sapiens(9606)Function
GO:0071682located_in endocytic vesicle lumen1TASHomo_sapiens(9606)Component
GO:0097110enables scaffold protein binding1IPIHomo_sapiens(9606)Function
GO:0097226located_in sperm mitochondrial sheath1IEAHomo_sapiens(9606)Component
GO:0097524located_in sperm plasma membrane1IEAHomo_sapiens(9606)Component
GO:0097718enables disordered domain specific binding2IBA,IPIHomo_sapiens(9606)Function
GO:0098586involved_in cellular response to virus1IDAHomo_sapiens(9606)Process
GO:0099072involved_in regulation of postsynaptic membrane neurotransmitter receptor levels1IEAHomo_sapiens(9606)Process
GO:0140662enables ATP-dependent protein folding chaperone1IEAHomo_sapiens(9606)Function
GO:1902949involved_in positive regulation of tau-protein kinase activity1IDAHomo_sapiens(9606)Process
GO:1904813located_in ficolin-1-rich granule lumen1TASHomo_sapiens(9606)Component
GO:1905323involved_in telomerase holoenzyme complex assembly1IDAHomo_sapiens(9606)Process
GO:1990782enables protein tyrosine kinase binding1IPIHomo_sapiens(9606)Function

Expression