Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Cancer Disease
Drug Drug
Main interacting RNAs N.A.
Moonlighting functions Kinase
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000175054 Gene ID 545 Accession 882
Symbol ATR Alias FRP1;MEC1;SCKL;FCTCS;SCKL1 Full Name ATR serine/threonine kinase
Status Confidence Length 129499 bases Strand Minus strand
Position 3 : 142449235 - 142578733 RNA binding domain N.A.
Summary The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
ATR-217 ENST00000658083 3537 No protein -
ATR-213 ENST00000656114 3220 No protein -
ATR-215 ENST00000656590 7056 2193aa ENSP00000499225
ATR-201 ENST00000350721 8158 2644aa ENSP00000343741
ATR-208 ENST00000515810 553 39aa ENSP00000421870
ATR-205 ENST00000513291 6835 No protein -
ATR-212 ENST00000654170 2961 No protein -
ATR-211 ENST00000653893 2940 No protein -
ATR-221 ENST00000666447 4534 No protein -
ATR-222 ENST00000666943 4763 No protein -
ATR-220 ENST00000665483 5569 No protein -
ATR-219 ENST00000661310 7838 2580aa ENSP00000499589
ATR-204 ENST00000511016 681 No protein -
ATR-210 ENST00000653868 8096 No protein -
ATR-206 ENST00000514393 552 No protein -
ATR-203 ENST00000507620 837 No protein -
ATR-214 ENST00000656582 2174 No protein -
ATR-207 ENST00000515149 2816 115aa ENSP00000425897
ATR-218 ENST00000659195 5945 No protein -
ATR-216 ENST00000657914 4678 No protein -
ATR-209 ENST00000515863 641 No protein -
ATR-202 ENST00000507148 724 100aa ENSP00000426595

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000175054homo_sapiensENSP0000040251517.23578.60421homo_sapiensENSP0000034374123.865411.9138
ENSG00000175054homo_sapiensENSP0000031342025.847913.0087homo_sapiensENSP0000034374140.355520.3101
ENSG00000175054homo_sapiensENSP0000035455823.77410.6709homo_sapiensENSP0000034374122.919810.2874
ENSG00000175054homo_sapiensENSP0000050160628.89414.7251homo_sapiensENSP0000034374133.396417.0197
ENSG00000175054homo_sapiensENSP0000039464521.40469.45004homo_sapiensENSP0000034374131.35413.8427

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000175054homo_sapiensENSP0000034374198.373797.6551nomascus_leucogenysENSNLEP0000002562999.274898.5496
ENSG00000175054homo_sapiensENSP0000034374197.692997.239pan_paniscusENSPPAP0000004034998.814198.355
ENSG00000175054homo_sapiensENSP0000034374199.659699.357pongo_abeliiENSPPYP0000001585399.659699.357
ENSG00000175054homo_sapiensENSP0000034374199.735399.584pan_troglodytesENSPTRP0000005101799.735399.584
ENSG00000175054homo_sapiensENSP0000034374199.773199.5461gorilla_gorillaENSGGOP0000003800699.773199.5461
ENSG00000175054homo_sapiensENSP0000034374189.031880.8245ornithorhynchus_anatinusENSOANP0000004176988.46380.3082
ENSG00000175054homo_sapiensENSP0000034374192.17185.9682sarcophilus_harrisiiENSSHAP0000001870191.685585.5154
ENSG00000175054homo_sapiensENSP0000034374161.308656.4675notamacropus_eugeniiENSMEUP0000000950562.418257.4894
ENSG00000175054homo_sapiensENSP0000034374159.94757.4887choloepus_hoffmanniENSCHOP0000000797163.425460.8243
ENSG00000175054homo_sapiensENSP0000034374196.974394.3268dasypus_novemcinctusENSDNOP0000000363896.937694.2911
ENSG00000175054homo_sapiensENSP0000034374174.546171.7095erinaceus_europaeusENSEEUP0000001096276.63373.7169
ENSG00000175054homo_sapiensENSP0000034374172.428169.1755echinops_telfairiENSETEP0000000282472.428169.1755
ENSG00000175054homo_sapiensENSP0000034374198.411597.239callithrix_jacchusENSCJAP0000000335598.411597.239
ENSG00000175054homo_sapiensENSP0000034374195.650594.705cercocebus_atysENSCATP0000002124298.289997.3183
ENSG00000175054homo_sapiensENSP0000034374199.508398.7519macaca_fascicularisENSMFAP0000000858899.508398.7519
ENSG00000175054homo_sapiensENSP0000034374199.470598.7141macaca_mulattaENSMMUP0000001040999.470598.7141
ENSG00000175054homo_sapiensENSP0000034374199.546198.7897macaca_nemestrinaENSMNEP0000000157499.546198.7897
ENSG00000175054homo_sapiensENSP0000034374199.546198.8654papio_anubisENSPANP0000001187499.546198.8654
ENSG00000175054homo_sapiensENSP0000034374199.432798.7141mandrillus_leucophaeusENSMLEP0000001300999.432798.7141
ENSG00000175054homo_sapiensENSP0000034374184.909282.0726tursiops_truncatusENSTTRP0000000951285.58982.7297
ENSG00000175054homo_sapiensENSP0000034374196.709594.2511vulpes_vulpesENSVVUP0000003369496.966294.5013
ENSG00000175054homo_sapiensENSP0000034374195.234590.6581mus_spretusMGP_SPRETEiJ_P009279895.342790.7611
ENSG00000175054homo_sapiensENSP0000034374196.785294.4781equus_asinusENSEASP0000500330293.190190.9687
ENSG00000175054homo_sapiensENSP0000034374196.217893.2678capra_hircusENSCHIP0000002504896.217893.2678
ENSG00000175054homo_sapiensENSP0000034374196.520493.7973loxodonta_africanaENSLAFP0000001294996.556993.8328
ENSG00000175054homo_sapiensENSP0000034374195.423693.1921panthera_leoENSPLOP0000002107097.225494.9518
ENSG00000175054homo_sapiensENSP0000034374197.428194.9697ailuropoda_melanoleucaENSAMEP0000001327197.428194.9697
ENSG00000175054homo_sapiensENSP0000034374196.82393.7595bos_indicus_hybridENSBIXP0000502812496.82393.7595
ENSG00000175054homo_sapiensENSP0000034374196.520493.1921oryctolagus_cuniculusENSOCUP0000000162696.556993.2274
ENSG00000175054homo_sapiensENSP0000034374197.428195.1589equus_caballusENSECAP0000002295793.367291.1925
ENSG00000175054homo_sapiensENSP0000034374197.23994.9319canis_lupus_familiarisENSCAFP0084503987297.23994.9319
ENSG00000175054homo_sapiensENSP0000034374197.23994.9697panthera_pardusENSPPRP0000000834897.275895.0057
ENSG00000175054homo_sapiensENSP0000034374194.856392.2844marmota_marmota_marmotaENSMMMP0000001958096.610293.9908
ENSG00000175054homo_sapiensENSP0000034374197.617294.6293balaenoptera_musculusENSBMSP0001000402697.617294.6293
ENSG00000175054homo_sapiensENSP0000034374191.338987.292cavia_porcellusENSCPOP0000000631395.116290.9019
ENSG00000175054homo_sapiensENSP0000034374197.276995.0076felis_catusENSFCAP0000001575497.313795.0435
ENSG00000175054homo_sapiensENSP0000034374116.754915.8094ursus_americanusENSUAMP0000000038193.067287.8151
ENSG00000175054homo_sapiensENSP000003437414.236013.66868monodelphis_domesticaENSMODP0000005241270.440361.0063
ENSG00000175054homo_sapiensENSP0000034374196.747493.7595bison_bison_bisonENSBBBP0000000886296.747493.7595
ENSG00000175054homo_sapiensENSP0000034374197.503894.5915monodon_monocerosENSMMNP0001500104697.466994.5558
ENSG00000175054homo_sapiensENSP0000034374196.709593.6838sus_scrofaENSSSCP0000007821796.417893.4012
ENSG00000175054homo_sapiensENSP0000034374197.692995.5371microcebus_murinusENSMICP0000005078697.729995.5732
ENSG00000175054homo_sapiensENSP0000034374194.099889.4478octodon_degusENSODEP0000001564194.78190.0952
ENSG00000175054homo_sapiensENSP0000034374193.494788.9939jaculus_jaculusENSJJAP0000001206794.821690.257
ENSG00000175054homo_sapiensENSP0000034374196.558293.4947ovis_aries_rambouilletENSOARP0002000887296.558293.4947
ENSG00000175054homo_sapiensENSP0000034374196.82394.3646ursus_maritimusENSUMAP0000001853697.0894.6151
ENSG00000175054homo_sapiensENSP0000034374154.425151.9289ochotona_princepsENSOPRP0000001288756.123253.5491
ENSG00000175054homo_sapiensENSP0000034374178.214876.4372delphinapterus_leucasENSDLEP0000000363097.685495.4653
ENSG00000175054homo_sapiensENSP000003437413.555223.25265delphinapterus_leucasENSDLEP0000000365090.384682.6923
ENSG00000175054homo_sapiensENSP0000034374197.390394.5159physeter_catodonENSPCTP0000500013997.390394.5159
ENSG00000175054homo_sapiensENSP0000034374143.419142.171mus_caroliMGP_CAROLIEiJ_P008910896.63393.8552
ENSG00000175054homo_sapiensENSP0000034374195.158990.469mus_musculusENSMUSP0000014995395.266990.5718
ENSG00000175054homo_sapiensENSP0000034374190.015184.6067dipodomys_ordiiENSDORP0000000036791.82186.304
ENSG00000175054homo_sapiensENSP0000034374197.087794.4024mustela_putorius_furoENSMPUP0000001193097.087794.4024
ENSG00000175054homo_sapiensENSP0000034374198.108996.7095aotus_nancymaaeENSANAP0000001500198.183296.7827
ENSG00000175054homo_sapiensENSP0000034374197.730796.407saimiri_boliviensis_boliviensisENSSBOP0000003144497.95396.6262
ENSG00000175054homo_sapiensENSP0000034374178.139276.0212vicugna_pacosENSVPAP0000000435378.168776.0499
ENSG00000175054homo_sapiensENSP0000034374199.508398.8275chlorocebus_sabaeusENSCSAP0000000748299.508398.8275
ENSG00000175054homo_sapiensENSP0000034374176.664173.1846tupaia_belangeriENSTBEP0000001205677.307473.7986
ENSG00000175054homo_sapiensENSP0000034374173.903269.2133mesocricetus_auratusENSMAUP0000001357990.968385.1955
ENSG00000175054homo_sapiensENSP0000034374197.617294.6672phocoena_sinusENSPSNP0000001210797.580394.6314
ENSG00000175054homo_sapiensENSP0000034374197.276994.4781camelus_dromedariusENSCDRP0000501528297.276994.4781
ENSG00000175054homo_sapiensENSP0000034374196.898694.3646carlito_syrichtaENSTSYP0000000250696.898694.3646
ENSG00000175054homo_sapiensENSP0000034374197.125694.8941panthera_tigris_altaicaENSPTIP0000002143797.162394.93
ENSG00000175054homo_sapiensENSP0000034374195.045490.7337rattus_norvegicusENSRNOP0000004376095.333891.0091
ENSG00000175054homo_sapiensENSP0000034374197.352595.1589prolemur_simusENSPSMP0000000950197.389395.1949
ENSG00000175054homo_sapiensENSP0000034374193.343489.0696microtus_ochrogasterENSMOCP0000001601795.289690.9266
ENSG00000175054homo_sapiensENSP0000034374181.505376.8911sorex_araneusENSSARP0000000411581.659777.0368
ENSG00000175054homo_sapiensENSP0000034374195.423691.1498peromyscus_maniculatus_bairdiiENSPEMP0000002623295.495891.2188
ENSG00000175054homo_sapiensENSP0000034374196.82393.7973bos_mutusENSBMUP0000002731696.82393.7973
ENSG00000175054homo_sapiensENSP0000034374195.045490.5446mus_spicilegusENSMSIP0000001928195.3790.8539
ENSG00000175054homo_sapiensENSP0000034374194.478190.5825cricetulus_griseus_chok1gshdENSCGRP0000101901495.672291.7273
ENSG00000175054homo_sapiensENSP0000034374193.456990.6581pteropus_vampyrusENSPVAP0000001535793.492290.6924
ENSG00000175054homo_sapiensENSP0000034374193.608290.6959myotis_lucifugusENSMLUP0000001541896.453693.4528
ENSG00000175054homo_sapiensENSP0000034374191.906285.8926vombatus_ursinusENSVURP0001001309791.49185.5045
ENSG00000175054homo_sapiensENSP0000034374196.898693.8729rhinolophus_ferrumequinumENSRFEP0001000751596.898693.8729
ENSG00000175054homo_sapiensENSP0000034374197.163494.6293neovison_visonENSNVIP0000001704197.200194.6652
ENSG00000175054homo_sapiensENSP0000034374195.726292.587bos_taurusENSBTAP0000006655395.043291.9264
ENSG00000175054homo_sapiensENSP0000034374196.217892.7761heterocephalus_glaber_femaleENSHGLP0000003620196.254392.8112
ENSG00000175054homo_sapiensENSP0000034374195.839694.8941rhinopithecus_bietiENSRBIP0000002729298.293397.3235
ENSG00000175054homo_sapiensENSP0000034374196.1893.7973canis_lupus_dingoENSCAFP0002001217695.673493.3032
ENSG00000175054homo_sapiensENSP0000034374197.049994.289sciurus_vulgarisENSSVLP0000501215597.049994.289
ENSG00000175054homo_sapiensENSP000003437413.101362.79879phascolarctos_cinereusENSPCIP0000003909772.566465.4867
ENSG00000175054homo_sapiensENSP0000034374180.408576.8154procavia_capensisENSPCAP0000001353683.60279.8663
ENSG00000175054homo_sapiensENSP0000034374194.553790.5068nannospalax_galiliENSNGAP0000002464494.876790.8159
ENSG00000175054homo_sapiensENSP0000034374196.82393.7973bos_grunniensENSBGRP0000000096196.82393.7973
ENSG00000175054homo_sapiensENSP0000034374195.953192.0575chinchilla_lanigeraENSCLAP0000000153895.953192.0575
ENSG00000175054homo_sapiensENSP0000034374196.898693.8351cervus_hanglu_yarkandensisENSCHYP0000003471896.898693.8351
ENSG00000175054homo_sapiensENSP0000034374197.087794.2511catagonus_wagneriENSCWAP0000001801797.234894.3939
ENSG00000175054homo_sapiensENSP0000034374196.633993.9486ictidomys_tridecemlineatusENSSTOP0000001576796.633993.9486
ENSG00000175054homo_sapiensENSP0000034374197.049993.9864otolemur_garnettiiENSOGAP0000000015297.123494.0575
ENSG00000175054homo_sapiensENSP0000034374198.487197.3525cebus_imitatorENSCCAP0000003960798.487197.3525
ENSG00000175054homo_sapiensENSP0000034374196.520493.7216urocitellus_parryiiENSUPAP0001001042596.520493.7216
ENSG00000175054homo_sapiensENSP0000034374196.785293.8729moschus_moschiferusENSMMSP0000000798696.785293.8729
ENSG00000175054homo_sapiensENSP0000034374194.251193.0787rhinopithecus_roxellanaENSRROP0000002449496.664195.4616
ENSG00000175054homo_sapiensENSP0000034374195.272390.8472mus_pahariMGP_PahariEiJ_P002476695.344490.916
ENSG00000175054homo_sapiensENSP0000034374197.730795.4992propithecus_coquereliENSPCOP0000001612097.767795.5354
ENSG00000175054homo_sapiensENSP0000034374143.608224.3949drosophila_melanogasterFBpp007404745.808525.6257
ENSG00000175054homo_sapiensENSP000003437414.765513.85779ciona_intestinalisENSCINP0000003105779.746864.557
ENSG00000175054homo_sapiensENSP000003437413.706512.76097ciona_intestinalisENSCINP0000000857966.666749.6599
ENSG00000175054homo_sapiensENSP000003437414.689862.9879ciona_intestinalisENSCINP0000003353356.62136.0731
ENSG00000175054homo_sapiensENSP0000034374167.776152.0802petromyzon_marinusENSPMAP0000000339767.015751.4959
ENSG00000175054homo_sapiensENSP0000034374110.43878.0938eptatretus_burgeriENSEBUP0000002491369.346753.7688
ENSG00000175054homo_sapiensENSP0000034374178.403966.112callorhinchus_miliiENSCMIP0000001406979.608367.1275
ENSG00000175054homo_sapiensENSP0000034374182.866972.0877latimeria_chalumnaeENSLACP0000001123782.554671.8161
ENSG00000175054homo_sapiensENSP0000034374178.063564.5991lepisosteus_oculatusENSLOCP0000000963677.916264.4772
ENSG00000175054homo_sapiensENSP0000034374175.41660.7413clupea_harengusENSCHAP0000003824176.019861.2276
ENSG00000175054homo_sapiensENSP0000034374177.571964.7882danio_rerioENSDARP0000011830477.836865.0095
ENSG00000175054homo_sapiensENSP0000034374177.571964.1452carassius_auratusENSCARP0000003731577.866464.3888
ENSG00000175054homo_sapiensENSP0000034374172.23959.7579astyanax_mexicanusENSAMXP0000005116078.439464.8871
ENSG00000175054homo_sapiensENSP0000034374176.777663.1241ictalurus_punctatusENSIPUP0000002287877.599463.7997
ENSG00000175054homo_sapiensENSP0000034374177.042464.1452electrophorus_electricusENSEEEP0000003327877.540964.5603
ENSG00000175054homo_sapiensENSP0000034374174.58460.2118oncorhynchus_kisutchENSOKIP0000504735374.35960.0302
ENSG00000175054homo_sapiensENSP0000034374174.546160.2874oncorhynchus_mykissENSOMYP0000010802775.22960.8397
ENSG00000175054homo_sapiensENSP000003437413.1772.72315salmo_salarENSSSAP0000010341179.245367.9245
ENSG00000175054homo_sapiensENSP0000034374174.810960.7035salmo_salarENSSSAP0000007449274.726160.6347
ENSG00000175054homo_sapiensENSP000003437413.025722.49622salmo_truttaENSSTUP0000007556380.808166.6667
ENSG00000175054homo_sapiensENSP0000034374173.411559.4554salmo_truttaENSSTUP0000002296873.774259.7491
ENSG00000175054homo_sapiensENSP0000034374170.650556.5809gadus_morhuaENSGMOP0000001379073.863259.1538
ENSG00000175054homo_sapiensENSP0000034374169.894157.5265fundulus_heteroclitusENSFHEP0000001573276.553463.0075
ENSG00000175054homo_sapiensENSP0000034374173.751959.9849poecilia_reticulataENSPREP0000001695575.318761.2592
ENSG00000175054homo_sapiensENSP0000034374169.478156.6566xiphophorus_maculatusENSXMAP0000000930875.194461.3181
ENSG00000175054homo_sapiensENSP0000034374164.031853.2905oryzias_latipesENSORLP0000001525178.379665.2315
ENSG00000175054homo_sapiensENSP0000034374173.033359.6067cyclopterus_lumpusENSCLMP0000504701674.642460.92
ENSG00000175054homo_sapiensENSP0000034374172.276958.2073oreochromis_niloticusENSONIP0000000097274.823860.2584
ENSG00000175054homo_sapiensENSP0000034374169.024256.5053haplochromis_burtoniENSHBUP0000001269758.139547.5948
ENSG00000175054homo_sapiensENSP0000034374171.369157.6021astatotilapia_callipteraENSACLP0000000838474.762360.3407
ENSG00000175054homo_sapiensENSP0000034374171.974358.5098sparus_aurataENSSAUP0001003280774.075560.218
ENSG00000175054homo_sapiensENSP0000034374172.579459.115lates_calcariferENSLCAP0001002918875.195961.2461
ENSG00000175054homo_sapiensENSP0000034374183.358672.7685xenopus_tropicalisENSXETP0000000134182.085771.6574
ENSG00000175054homo_sapiensENSP0000034374188.918379.9168chrysemys_picta_belliiENSCPBP0000001172188.350279.4062
ENSG00000175054homo_sapiensENSP000003437412.45842.118sphenodon_punctatusENSSPUP0000001387192.857180
ENSG00000175054homo_sapiensENSP0000034374110.24969.30408sphenodon_punctatusENSSPUP0000001388787.702379.6116
ENSG00000175054homo_sapiensENSP000003437413.403933.06354sphenodon_punctatusENSSPUP0000001389892.783583.5052
ENSG00000175054homo_sapiensENSP0000034374111.686811.1952sphenodon_punctatusENSSPUP0000001392996.261792.2118
ENSG00000175054homo_sapiensENSP000003437413.51742.6475sphenodon_punctatusENSSPUP0000001385073.228355.1181
ENSG00000175054homo_sapiensENSP0000034374113.615712.2542sphenodon_punctatusENSSPUP0000001391490.909181.8182
ENSG00000175054homo_sapiensENSP0000034374111.68689.03933sphenodon_punctatusENSSPUP0000001385979.230861.2821
ENSG00000175054homo_sapiensENSP000003437413.593043.21483sphenodon_punctatusENSSPUP0000001384090.476280.9524
ENSG00000175054homo_sapiensENSP0000034374188.010678.6687crocodylus_porosusENSCPRP0000500230787.977378.6389
ENSG00000175054homo_sapiensENSP0000034374152.042443.2678laticauda_laticaudataENSLLTP0000000792678.673565.4088
ENSG00000175054homo_sapiensENSP0000034374183.547772.3525notechis_scutatusENSNSUP0000002518684.024372.7653
ENSG00000175054homo_sapiensENSP0000034374182.677871.5204pseudonaja_textilisENSPTXP0000000622583.403372.148
ENSG00000175054homo_sapiensENSP000003437413.744333.29047anas_platyrhynchos_platyrhynchosENSAPLP0000001784479.269.6
ENSG00000175054homo_sapiensENSP0000034374186.838177.7988gallus_gallusENSGALP0001002188686.315877.3308
ENSG00000175054homo_sapiensENSP000003437413.366112.72315meleagris_gallopavoENSMGAP0000002876777.391362.6087
ENSG00000175054homo_sapiensENSP0000034374164.031858.7746meleagris_gallopavoENSMGAP0000003452589.058481.7465
ENSG00000175054homo_sapiensENSP0000034374184.682375.7564serinus_canariaENSSCAP0000000093286.414577.3061
ENSG00000175054homo_sapiensENSP0000034374149.886545.9909anolis_carolinensisENSACAP0000000484890.404483.3448
ENSG00000175054homo_sapiensENSP0000034374172.995558.9259neolamprologus_brichardiENSNBRP0000001165475.214360.7171
ENSG00000175054homo_sapiensENSP0000034374111.91389.22844podarcis_muralisENSPMRP0000001250175.903658.7952
ENSG00000175054homo_sapiensENSP0000034374182.526573.7141geospiza_fortisENSGFOP0000001152886.518677.2799
ENSG00000175054homo_sapiensENSP0000034374187.065177.761taeniopygia_guttataENSTGUP0000000884086.606577.3514
ENSG00000175054homo_sapiensENSP0000034374177.231565.5446erpetoichthys_calabaricusENSECRP0000002158980.967568.7153
ENSG00000175054homo_sapiensENSP000003437413.366112.53404kryptolebias_marmoratusENSKMAP0000000105381.651461.4679
ENSG00000175054homo_sapiensENSP0000034374184.720174.5461salvator_merianaeENSSMRP0000002108284.115774.0143
ENSG00000175054homo_sapiensENSP0000034374172.163458.7368amphilophus_citrinellusENSACIP0000000695375.714361.627
ENSG00000175054homo_sapiensENSP0000034374174.205760.0983dicentrarchus_labraxENSDLAP0000506564175.143660.8579
ENSG00000175054homo_sapiensENSP0000034374172.201259.115amphiprion_perculaENSAPEP0000001735474.980461.3904
ENSG00000175054homo_sapiensENSP0000034374188.577979.6142pelodiscus_sinensisENSPSIP0000002019988.01279.1056
ENSG00000175054homo_sapiensENSP0000034374188.804879.8411gopherus_evgoodeiENSGEVP0000501257888.237579.3311
ENSG00000175054homo_sapiensENSP0000034374188.237579.1225chelonoidis_abingdoniiENSCABP0000000942388.137579.0329
ENSG00000175054homo_sapiensENSP0000034374167.057555.7867seriola_dumeriliENSSDUP0000001648478.870165.6139
ENSG00000175054homo_sapiensENSP0000034374149.243642.3222cottoperca_gobioENSCGOP0000005520780.669169.3309
ENSG00000175054homo_sapiensENSP0000034374184.53175.6808struthio_camelus_australisENSSCUP0000001993086.96577.8599
ENSG00000175054homo_sapiensENSP0000034374186.951677.7988anser_brachyrhynchusENSABRP0000001067686.689377.5641
ENSG00000175054homo_sapiensENSP0000034374173.714160.0227gasterosteus_aculeatusENSGACP0000001432273.408759.774
ENSG00000175054homo_sapiensENSP0000034374168.154355.0681cynoglossus_semilaevisENSCSEP0000000572874.186959.9424
ENSG00000175054homo_sapiensENSP0000034374174.508360.0605poecilia_formosaENSPFOP0000001368774.032359.6768
ENSG00000175054homo_sapiensENSP0000034374173.94160.2496myripristis_murdjanENSMMDP0000504133075.04861.1516
ENSG00000175054homo_sapiensENSP0000034374174.092360.0227sander_luciopercaENSSLUP0000005871975.812761.4164
ENSG00000175054homo_sapiensENSP0000034374187.254278.0257strigops_habroptilaENSSHBP0000502274486.729377.5564
ENSG00000175054homo_sapiensENSP0000034374172.125659.0393amphiprion_ocellarisENSAOCP0000002905374.931261.336
ENSG00000175054homo_sapiensENSP0000034374188.653679.8033terrapene_carolina_triunguisENSTMTP0000002740588.653679.8033
ENSG00000175054homo_sapiensENSP0000034374150.756443.7216hucho_huchoENSHHUP0000002696081.087669.8489
ENSG00000175054homo_sapiensENSP000003437414.04692.79879hucho_huchoENSHHUP0000007865367.295646.5409
ENSG00000175054homo_sapiensENSP000003437415.521944.00908hucho_huchoENSHHUP0000002993073.737453.5354
ENSG00000175054homo_sapiensENSP000003437413.593042.9879hucho_huchoENSHHUP0000008693783.333369.2982
ENSG00000175054homo_sapiensENSP0000034374176.323863.0862pygocentrus_nattereriENSPNAP0000001396877.70564.228
ENSG00000175054homo_sapiensENSP0000034374124.394917.6626ciona_savignyiENSCSAVP0000001867468.181849.3657
ENSG00000175054homo_sapiensENSP000003437412.836612.26929seriola_lalandi_dorsalisENSSLDP0000003153770.754756.6038
ENSG00000175054homo_sapiensENSP0000034374158.320750.0378seriola_lalandi_dorsalisENSSLDP0000003151185.099373.0132
ENSG00000175054homo_sapiensENSP0000034374170.461457.7912labrus_bergyltaENSLBEP0000003785476.446462.7
ENSG00000175054homo_sapiensENSP0000034374170.007657.4508pundamilia_nyerereiENSPNYP0000000913775.736562.1522
ENSG00000175054homo_sapiensENSP0000034374173.600659.8714mastacembelus_armatusENSMAMP0000003999875.397161.3328
ENSG00000175054homo_sapiensENSP0000034374171.217858.3207stegastes_partitusENSSPAP0000000368375.440761.7788
ENSG00000175054homo_sapiensENSP0000034374170.158957.8669acanthochromis_polyacanthusENSAPOP0000000835077.066963.5646
ENSG00000175054homo_sapiensENSP0000034374187.70878.4796aquila_chrysaetos_chrysaetosENSACCP0002000648887.840978.5985
ENSG00000175054homo_sapiensENSP0000034374171.898658.6611cyprinodon_variegatusENSCVAP0000003088975.979261.9904
ENSG00000175054homo_sapiensENSP0000034374176.891163.5401denticeps_clupeoidesENSDCDP0000004083077.477164.0244
ENSG00000175054homo_sapiensENSP0000034374174.092360.2874larimichthys_croceaENSLCRP0000503714675.491361.4258
ENSG00000175054homo_sapiensENSP0000034374173.903259.3797takifugu_rubripesENSTRUP0000003541975.182860.4078
ENSG00000175054homo_sapiensENSP000003437414.122543.32829ficedula_albicollisENSFALP0000003212842.578134.375
ENSG00000175054homo_sapiensENSP000003437413.290472.53404hippocampus_comesENSHCOP0000002513582.075563.2075
ENSG00000175054homo_sapiensENSP0000034374178.025764.2587cyprinus_carpio_carpioENSCCRP0000013020078.262564.4537
ENSG00000175054homo_sapiensENSP0000034374186.270877.4962coturnix_japonicaENSCJPP0000501329586.79677.968
ENSG00000175054homo_sapiensENSP0000034374166.94455.5219poecilia_latipinnaENSPLAP0000000622777.699764.4425
ENSG00000175054homo_sapiensENSP0000034374157.564348.7897sinocyclocheilus_grahamiENSSGRP0000002451479.644267.5039
ENSG00000175054homo_sapiensENSP000003437413.403932.79879sinocyclocheilus_grahamiENSSGRP0000003965977.586263.7931
ENSG00000175054homo_sapiensENSP000003437413.214832.6475sinocyclocheilus_grahamiENSSGRP0000000563078.703764.8148
ENSG00000175054homo_sapiensENSP0000034374172.579458.6989maylandia_zebraENSMZEP0000500420475.13760.7674
ENSG00000175054homo_sapiensENSP0000034374160.627851.3616tetraodon_nigroviridisENSTNIP0000002264082.714170.0722
ENSG00000175054homo_sapiensENSP0000034374176.248163.767paramormyrops_kingsleyaeENSPKIP0000000514678.321765.5012
ENSG00000175054homo_sapiensENSP0000034374178.17765.2799scleropages_formosusENSSFOP0001501335178.354865.4284
ENSG00000175054homo_sapiensENSP0000034374183.05672.466leptobrachium_leishanenseENSLLEP0000001474782.805472.2474
ENSG00000175054homo_sapiensENSP0000034374172.012158.3585scophthalmus_maximusENSSMAP0000004698875.947361.5477
ENSG00000175054homo_sapiensENSP000003437413.555222.95008oryzias_melastigmaENSOMEP0000003119281.034567.2414

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000077involved_in DNA damage checkpoint signaling2IBA,IDAHomo_sapiens(9606)Process
GO:0000723involved_in telomere maintenance1IBAHomo_sapiens(9606)Process
GO:0000781colocalizes_with chromosome, telomeric region1ICHomo_sapiens(9606)Component
GO:0003677enables DNA binding1IEAHomo_sapiens(9606)Function
GO:0004672enables protein kinase activity1IDAHomo_sapiens(9606)Function
GO:0004674enables protein serine/threonine kinase activity3IBA,IDA,TASHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IEAHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus2IBA,NASHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005694located_in chromosome1ISSHomo_sapiens(9606)Component
GO:0005794located_in Golgi apparatus1IDAHomo_sapiens(9606)Component
GO:0006139involved_in nucleobase-containing compound metabolic process1NASHomo_sapiens(9606)Process
GO:0006260involved_in DNA replication1TASHomo_sapiens(9606)Process
GO:0006281involved_in DNA repair1TASHomo_sapiens(9606)Process
GO:0006468involved_in protein phosphorylation1IBAHomo_sapiens(9606)Process
GO:0006974involved_in DNA damage response2IDA,TASHomo_sapiens(9606)Process
GO:0008156involved_in negative regulation of DNA replication1IMPHomo_sapiens(9606)Process
GO:0009410involved_in response to xenobiotic stimulus1IEAHomo_sapiens(9606)Process
GO:0016605located_in PML body1IDAHomo_sapiens(9606)Component
GO:0018105involved_in peptidyl-serine phosphorylation1IDAHomo_sapiens(9606)Process
GO:0031297involved_in replication fork processing1ISSHomo_sapiens(9606)Process
GO:0032212involved_in positive regulation of telomere maintenance via telomerase1ISSHomo_sapiens(9606)Process
GO:0032405enables MutLalpha complex binding1IDAHomo_sapiens(9606)Function
GO:0032407enables MutSalpha complex binding1IDAHomo_sapiens(9606)Function
GO:0034644involved_in cellular response to UV1IMPHomo_sapiens(9606)Process
GO:0036297involved_in interstrand cross-link repair1TASHomo_sapiens(9606)Process
GO:0043517involved_in positive regulation of DNA damage response, signal transduction by p53 class mediator1IMPHomo_sapiens(9606)Process
GO:0046685involved_in response to arsenic-containing substance1IEAHomo_sapiens(9606)Process
GO:0046777involved_in protein autophosphorylation1IDAHomo_sapiens(9606)Process
GO:0070198involved_in protein localization to chromosome, telomeric region1IMPHomo_sapiens(9606)Process
GO:0070310part_of ATR-ATRIP complex1IPIHomo_sapiens(9606)Component
GO:0071480involved_in cellular response to gamma radiation1IDAHomo_sapiens(9606)Process
GO:0090399involved_in replicative senescence1IMPHomo_sapiens(9606)Process
GO:0097694involved_in establishment of RNA localization to telomere1IMPHomo_sapiens(9606)Process
GO:0097695involved_in establishment of protein-containing complex localization to telomere1ICHomo_sapiens(9606)Process
GO:0106310enables protein serine kinase activity1IEAHomo_sapiens(9606)Function
GO:1900034involved_in regulation of cellular response to heat1TASHomo_sapiens(9606)Process
GO:1904884involved_in positive regulation of telomerase catalytic core complex assembly1IMPHomo_sapiens(9606)Process
GO:2000779involved_in regulation of double-strand break repair1NASHomo_sapiens(9606)Process

Expression