Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerSARS-COV-2Dengue
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000205937 Gene ID 10921 Accession 10080
Symbol RNPS1 Alias E5.1 Full Name RNA binding protein with serine rich domain 1
Status Confidence Length 15282 bases Strand Minus strand
Position 16 : 2253116 - 2268397 RNA binding domain RRM_1
Summary This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000457987 RRM_1 PF00076 1.1e-17 1
ENSP00000454461 RRM_1 PF00076 1.8e-17 1
ENSP00000456352 RRM_1 PF00076 1.8e-17 1
ENSP00000457110 RRM_1 PF00076 2e-17 1
ENSP00000301730 RRM_1 PF00076 2e-17 1
ENSP00000315859 RRM_1 PF00076 2e-17 1
ENSP00000380275 RRM_1 PF00076 2e-17 1
ENSP00000457723 RRM_1 PF00076 2e-17 1
ENSP00000457820 RRM_1 PF00076 2e-17 1
ENSP00000454513 RRM_1 PF00076 3.4e-15 1
ENSP00000455306 RRM_1 PF00076 1.9e-13 1
ENSP00000455379 RRM_1 PF00076 1.9e-13 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
27943637 Quantitative proteomic profiling of paired cancerous and normal colon epithelial cells isolated freshly from colorectal cancer patients. Chengjian Tu 2017-05-01 Proteomics. Clinical applications
31363108 A bioinformatic analysis identifies circadian expression of splicing factors and time-dependent alternative splicing events in the HD-MY-Z cell line. Nikolai Genov 2019-07-30 Scientific reports
27207777 Cyclin-Dependent Kinase 11 (CDK11) Is Required for Ovarian Cancer Cell Growth In Vitro and In Vivo, and Its Inhibition Causes Apoptosis and Sensitizes Cells to Paclitaxel. Xianzhe Liu 2016-07-01 Molecular cancer therapeutics
35939184 Molecular cloning, expression and generation of a polyclonal antibody specific for RNPS1. Bhagyashree Deka 2022-09-01 Molecular biology reports
22363630 Post-transcriptional regulation of 5-lipoxygenase mRNA expression via alternative splicing and nonsense-mediated mRNA decay. J Meike Ochs 2012-01-01 PloS one
35482923 RNPS1 inhibits excessive tumor necrosis factor/tumor necrosis factor receptor signaling to support hematopoiesis in mice. Xue Zhong 2022-05-03 Proceedings of the National Academy of Sciences of the United States of America
30466796 The Exon Junction Complex Undergoes a Compositional Switch that Alters mRNP Structure and Nonsense-Mediated mRNA Decay Activity. W Justin Mabin 2018-11-27 Cell reports
28539829 Multifaceted Regulation of Gene Expression by the Apoptosis- and Splicing-Associated Protein Complex and Its Components. Bhagyashree Deka 2017-01-01 International journal of biological sciences
11477570 Binding of a SART3 tumor-rejection antigen to a pre-mRNA splicing factor RNPS1: a possible regulation of splicing by a complex formation. K Harada 2001-09-01 International journal of cancer
32575694 Suppression of Nonsense Mutations by New Emerging Technologies. Pedro Morais 2020-06-20 International journal of molecular sciences
35551602 No-nonsense: insights into the functional interplay of nonsense-mediated mRNA decay factors. Justine Mailliot 2022-05-13 The Biochemical journal
35640609 Exon junction complex-associated multi-adapter RNPS1 nucleates splicing regulatory complexes to maintain transcriptome surveillance. P Lena Schlautmann 2022-06-10 Nucleic acids research
19744340 Glucocorticoids with different chemical structures but similar glucocorticoid receptor potency regulate subsets of common and unique genes in human trabecular meshwork cells. Alissar Nehmé 2009-09-10 BMC medical genomics
32467309 Chemical crosslinking enhances RNA immunoprecipitation for efficient identification of binding sites of proteins that photo-crosslink poorly with RNA. D Robert Patton 2020-09-01 RNA (New York, N.Y.)
30388412 Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons. Thomas Gonatopoulos-Pournatzis 2018-11-01 Molecular cell
24353314 NKAP is a novel RS-related protein that interacts with RNA and RNA binding proteins. D Bhagyashri Burgute 2014-03-01 Nucleic acids research

Transcripts

Name Transcript ID bp Protein Translation ID
RNPS1-203 ENST00000397086 2069 305aa ENSP00000380275
RNPS1-220 ENST00000566458 2037 282aa ENSP00000456352
RNPS1-202 ENST00000320225 1951 305aa ENSP00000315859
RNPS1-206 ENST00000562205 2223 No protein -
RNPS1-219 ENST00000566397 1685 128aa ENSP00000455379
RNPS1-216 ENST00000565678 2298 305aa ENSP00000457723
RNPS1-205 ENST00000561718 1806 128aa ENSP00000455306
RNPS1-223 ENST00000568631 1792 305aa ENSP00000457820
RNPS1-224 ENST00000569598 918 211aa ENSP00000457987
RNPS1-201 ENST00000301730 1276 305aa ENSP00000301730
RNPS1-222 ENST00000567147 830 257aa ENSP00000454513
RNPS1-213 ENST00000565243 3337 No protein -
RNPS1-217 ENST00000565870 1514 302aa ENSP00000457110
RNPS1-204 ENST00000561518 1092 284aa ENSP00000454461
RNPS1-209 ENST00000564311 870 156aa ENSP00000455013
RNPS1-226 ENST00000570051 735 No protein -
RNPS1-210 ENST00000564601 903 169aa ENSP00000457690
RNPS1-211 ENST00000564764 639 150aa ENSP00000457378
RNPS1-218 ENST00000566180 814 139aa ENSP00000457618
RNPS1-207 ENST00000562690 582 127aa ENSP00000457296
RNPS1-225 ENST00000569709 574 98aa ENSP00000455195
RNPS1-214 ENST00000565333 479 85aa ENSP00000454867
RNPS1-208 ENST00000563857 739 No protein -
RNPS1-215 ENST00000565589 666 45aa ENSP00000457338
RNPS1-212 ENST00000564822 314 29aa ENSP00000456283
RNPS1-221 ENST00000566783 1826 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
14926Hemoglobin A, Glycosylated5.8350000E-00519875614

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000205937

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000205937homo_sapiensENSP0000031585987.868987.541nomascus_leucogenysENSNLEP0000004597198.529498.1618
ENSG00000205937homo_sapiensENSP0000031585993.770593.4426pan_paniscusENSPPAP0000000273897.945297.6027
ENSG00000205937homo_sapiensENSP00000315859100100pongo_abeliiENSPPYP00000029940100100
ENSG00000205937homo_sapiensENSP0000031585999.672199.6721pan_troglodytesENSPTRP0000006711199.672199.6721
ENSG00000205937homo_sapiensENSP00000315859100100gorilla_gorillaENSGGOP00000048160100100
ENSG00000205937homo_sapiensENSP0000031585985.573880.6557ornithorhynchus_anatinusENSOANP0000003684257.743454.4248
ENSG00000205937homo_sapiensENSP0000031585999.672198.0328sarcophilus_harrisiiENSSHAP0000003954799.346497.7124
ENSG00000205937homo_sapiensENSP0000031585998.360796.7213notamacropus_eugeniiENSMEUP0000000810498.360796.7213
ENSG00000205937homo_sapiensENSP0000031585999.344398.3607choloepus_hoffmanniENSCHOP0000000430810099.0099
ENSG00000205937homo_sapiensENSP00000315859100100dasypus_novemcinctusENSDNOP00000012471100100
ENSG00000205937homo_sapiensENSP0000031585980.983680.9836erinaceus_europaeusENSEEUP0000000540280.983680.9836
ENSG00000205937homo_sapiensENSP0000031585980.655779.3443echinops_telfairiENSETEP000000025288280.6667
ENSG00000205937homo_sapiensENSP00000315859100100callithrix_jacchusENSCJAP00000027582100100
ENSG00000205937homo_sapiensENSP00000315859100100cercocebus_atysENSCATP00000003619100100
ENSG00000205937homo_sapiensENSP00000315859100100macaca_fascicularisENSMFAP00000029846100100
ENSG00000205937homo_sapiensENSP00000315859100100macaca_mulattaENSMMUP00000073148100100
ENSG00000205937homo_sapiensENSP0000031585989.836187.8689macaca_nemestrinaENSMNEP0000000545296.140494.0351
ENSG00000205937homo_sapiensENSP00000315859100100papio_anubisENSPANP00000013692100100
ENSG00000205937homo_sapiensENSP00000315859100100mandrillus_leucophaeusENSMLEP00000025458100100
ENSG00000205937homo_sapiensENSP00000315859100100tursiops_truncatusENSTTRP00000007784100100
ENSG00000205937homo_sapiensENSP00000315859100100vulpes_vulpesENSVVUP00000012617100100
ENSG00000205937homo_sapiensENSP00000315859100100mus_spretusMGP_SPRETEiJ_P0044961100100
ENSG00000205937homo_sapiensENSP0000031585997.049293.7705equus_asinusENSEASP0000500657872.195169.7561
ENSG00000205937homo_sapiensENSP0000031585968.524659.3443capra_hircusENSCHIP0000003375372.06962.4138
ENSG00000205937homo_sapiensENSP0000031585973.114862.623capra_hircusENSCHIP0000002109376.896665.8621
ENSG00000205937homo_sapiensENSP0000031585990.491888.8525loxodonta_africanaENSLAFP0000000061588.178986.5815
ENSG00000205937homo_sapiensENSP0000031585910099.6721panthera_leoENSPLOP0000002912010099.6721
ENSG00000205937homo_sapiensENSP0000031585996.065693.1148ailuropoda_melanoleucaENSAMEP0000002591787.202484.5238
ENSG00000205937homo_sapiensENSP0000031585987.868984.2623bos_indicus_hybridENSBIXP0000500101175.49372.3944
ENSG00000205937homo_sapiensENSP0000031585944.262339.6721oryctolagus_cuniculusENSOCUP0000002341761.643855.2511
ENSG00000205937homo_sapiensENSP0000031585997.049293.7705equus_caballusENSECAP0000004926472.195169.7561
ENSG00000205937homo_sapiensENSP00000315859100100canis_lupus_familiarisENSCAFP00845006331100100
ENSG00000205937homo_sapiensENSP0000031585910099.6721panthera_pardusENSPPRP0000002006910099.6721
ENSG00000205937homo_sapiensENSP0000031585999.672199.3443marmota_marmota_marmotaENSMMMP0000001070999.672199.3443
ENSG00000205937homo_sapiensENSP00000315859100100balaenoptera_musculusENSBMSP00010016410100100
ENSG00000205937homo_sapiensENSP0000031585999.672199.6721cavia_porcellusENSCPOP0000002655799.672199.6721
ENSG00000205937homo_sapiensENSP0000031585910099.6721felis_catusENSFCAP0000004581110099.6721
ENSG00000205937homo_sapiensENSP0000031585974.426272.1311ursus_americanusENSUAMP0000000492480.21277.7385
ENSG00000205937homo_sapiensENSP0000031585999.344397.7049monodelphis_domesticaENSMODP0000001982899.344397.7049
ENSG00000205937homo_sapiensENSP0000031585999.344399.3443bison_bison_bisonENSBBBP0000002504199.344399.3443
ENSG00000205937homo_sapiensENSP00000315859100100monodon_monocerosENSMMNP00015009380100100
ENSG00000205937homo_sapiensENSP0000031585985.901682.9508sus_scrofaENSSSCP0000000859676.832874.1936
ENSG00000205937homo_sapiensENSP0000031585999.672199.3443microcebus_murinusENSMICP0000002345899.672199.3443
ENSG00000205937homo_sapiensENSP0000031585949.508247.8689octodon_degusENSODEP0000002355886.285783.4286
ENSG00000205937homo_sapiensENSP0000031585933.442631.8033octodon_degusENSODEP0000000509089.473785.0877
ENSG00000205937homo_sapiensENSP0000031585950.163945.5738octodon_degusENSODEP0000000327085.955178.0899
ENSG00000205937homo_sapiensENSP0000031585987.213182.9508jaculus_jaculusENSJJAP0000001777278.466174.6313
ENSG00000205937homo_sapiensENSP0000031585999.672199.3443ovis_aries_rambouilletENSOARP0002003414599.672199.3443
ENSG00000205937homo_sapiensENSP00000315859100100ursus_maritimusENSUMAP00000030898100100
ENSG00000205937homo_sapiensENSP0000031585998.032896.7213ochotona_princepsENSOPRP0000001499398.679997.3597
ENSG00000205937homo_sapiensENSP0000031585986.229584.2623delphinapterus_leucasENSDLEP0000001547891.95889.8601
ENSG00000205937homo_sapiensENSP0000031585961.967260physeter_catodonENSPCTP0000500104684.753482.0628
ENSG00000205937homo_sapiensENSP0000031585934.098431.8033physeter_catodonENSPCTP0000500356272.727367.8322
ENSG00000205937homo_sapiensENSP0000031585976.393476.3934mus_caroliMGP_CAROLIEiJ_P004305186.940386.9403
ENSG00000205937homo_sapiensENSP00000315859100100mus_musculusENSMUSP00000126345100100
ENSG00000205937homo_sapiensENSP0000031585999.344399.3443dipodomys_ordiiENSDORP0000002022099.344399.3443
ENSG00000205937homo_sapiensENSP0000031585999.672199.6721aotus_nancymaaeENSANAP0000002211199.672199.6721
ENSG00000205937homo_sapiensENSP00000315859100100saimiri_boliviensis_boliviensisENSSBOP00000022808100100
ENSG00000205937homo_sapiensENSP0000031585992.131192.1311vicugna_pacosENSVPAP0000000928592.131192.1311
ENSG00000205937homo_sapiensENSP0000031585990.491890.4918chlorocebus_sabaeusENSCSAP0000000153992.617492.6174
ENSG00000205937homo_sapiensENSP0000031585989.180389.1803tupaia_belangeriENSTBEP00000007880100100
ENSG00000205937homo_sapiensENSP0000031585941.967241.9672mesocricetus_auratusENSMAUP00000003563100100
ENSG00000205937homo_sapiensENSP00000315859100100phocoena_sinusENSPSNP00000023610100100
ENSG00000205937homo_sapiensENSP0000031585999.672199.6721camelus_dromedariusENSCDRP0000502262299.672199.6721
ENSG00000205937homo_sapiensENSP00000315859100100carlito_syrichtaENSTSYP00000022444100100
ENSG00000205937homo_sapiensENSP0000031585957.37757.0492panthera_tigris_altaicaENSPTIP0000001712192.105391.5789
ENSG00000205937homo_sapiensENSP0000031585999.672199.6721rattus_norvegicusENSRNOP0000008957299.672199.6721
ENSG00000205937homo_sapiensENSP0000031585987.54184.5902rattus_norvegicusENSRNOP0000007783387.254984.3137
ENSG00000205937homo_sapiensENSP0000031585999.672199.6721prolemur_simusENSPSMP0000003306699.672199.6721
ENSG00000205937homo_sapiensENSP00000315859100100microtus_ochrogasterENSMOCP00000004225100100
ENSG00000205937homo_sapiensENSP0000031585988.524688.1967sorex_araneusENSSARP0000000142696.428696.0714
ENSG00000205937homo_sapiensENSP00000315859100100peromyscus_maniculatus_bairdiiENSPEMP00000012469100100
ENSG00000205937homo_sapiensENSP0000031585957.37750.4918bos_mutusENSBMUP0000003582366.793958.7786
ENSG00000205937homo_sapiensENSP0000031585933.770529.1803bos_mutusENSBMUP0000003498079.230868.4615
ENSG00000205937homo_sapiensENSP0000031585994.426293.1148mus_spicilegusENSMSIP0000000647093.811192.5081
ENSG00000205937homo_sapiensENSP00000315859100100cricetulus_griseus_chok1gshdENSCGRP00001021650100100
ENSG00000205937homo_sapiensENSP0000031585910099.6721pteropus_vampyrusENSPVAP0000000483010099.6721
ENSG00000205937homo_sapiensENSP00000315859100100myotis_lucifugusENSMLUP00000015315100100
ENSG00000205937homo_sapiensENSP0000031585910097.7049vombatus_ursinusENSVURP0001001245910097.7049
ENSG00000205937homo_sapiensENSP00000315859100100rhinolophus_ferrumequinumENSRFEP00010032903100100
ENSG00000205937homo_sapiensENSP0000031585999.344399.0164neovison_visonENSNVIP0000002967299.344399.0164
ENSG00000205937homo_sapiensENSP0000031585995.08293.1148bos_taurusENSBTAP0000006132279.019177.3842
ENSG00000205937homo_sapiensENSP0000031585958.688557.7049heterocephalus_glaber_femaleENSHGLP0000004363593.229291.6667
ENSG00000205937homo_sapiensENSP0000031585991.475491.1475rhinopithecus_bietiENSRBIP0000003017498.936298.5816
ENSG00000205937homo_sapiensENSP00000315859100100canis_lupus_dingoENSCAFP00020033697100100
ENSG00000205937homo_sapiensENSP0000031585999.672199.3443sciurus_vulgarisENSSVLP0000503041799.672199.3443
ENSG00000205937homo_sapiensENSP0000031585964.91864.2623phascolarctos_cinereusENSPCIP0000002124096.585495.6098
ENSG00000205937homo_sapiensENSP0000031585999.672198.0328phascolarctos_cinereusENSPCIP0000003371999.672198.0328
ENSG00000205937homo_sapiensENSP0000031585999.344397.7049procavia_capensisENSPCAP0000000421499.344397.7049
ENSG00000205937homo_sapiensENSP0000031585999.672199.6721nannospalax_galiliENSNGAP00000025895100100
ENSG00000205937homo_sapiensENSP0000031585986.557483.6066bos_grunniensENSBGRP0000003187383.280880.4416
ENSG00000205937homo_sapiensENSP0000031585999.672199.6721chinchilla_lanigeraENSCLAP0000002267699.672199.6721
ENSG00000205937homo_sapiensENSP0000031585999.672199.6721cervus_hanglu_yarkandensisENSCHYP0000000639099.672199.6721
ENSG00000205937homo_sapiensENSP0000031585910099.6721catagonus_wagneriENSCWAP0000001891610099.6721
ENSG00000205937homo_sapiensENSP0000031585988.524688.1967ictidomys_tridecemlineatusENSSTOP0000001183299.63199.262
ENSG00000205937homo_sapiensENSP0000031585942.950842.9508otolemur_garnettiiENSOGAP0000002256399.242499.2424
ENSG00000205937homo_sapiensENSP0000031585999.672199.6721cebus_imitatorENSCCAP0000003291699.672199.6721
ENSG00000205937homo_sapiensENSP0000031585999.672199.3443urocitellus_parryiiENSUPAP0001002239699.672199.3443
ENSG00000205937homo_sapiensENSP0000031585999.672199.3443moschus_moschiferusENSMMSP0000001738099.672199.3443
ENSG00000205937homo_sapiensENSP0000031585989.180389.1803rhinopithecus_roxellanaENSRROP0000003554089.473789.4737
ENSG00000205937homo_sapiensENSP0000031585999.672199.3443mus_pahariMGP_PahariEiJ_P005535010099.6711
ENSG00000205937homo_sapiensENSP0000031585999.672199.6721propithecus_coquereliENSPCOP0000000176499.672199.6721
ENSG00000205937homo_sapiensENSP0000031585949.836140.3279caenorhabditis_elegansK02F3.11.152.595242.5606
ENSG00000205937homo_sapiensENSP0000031585955.08242.2951drosophila_melanogasterFBpp011144823.728818.2203
ENSG00000205937homo_sapiensENSP0000031585943.278733.4426ciona_intestinalisENSCINP0000002834667.346952.0408
ENSG00000205937homo_sapiensENSP0000031585958.688544.918eptatretus_burgeriENSEBUP0000000736766.542750.9294
ENSG00000205937homo_sapiensENSP0000031585988.196777.3771callorhinchus_miliiENSCMIP0000001866692.439981.0997
ENSG00000205937homo_sapiensENSP0000031585988.196781.9672latimeria_chalumnaeENSLACP0000000803794.718388.0282
ENSG00000205937homo_sapiensENSP0000031585986.557478.6885lepisosteus_oculatusENSLOCP0000000202693.61785.1064
ENSG00000205937homo_sapiensENSP0000031585970.163963.2787clupea_harengusENSCHAP0000004329791.063882.1277
ENSG00000205937homo_sapiensENSP0000031585982.950874.0984clupea_harengusENSCHAP0000000028089.399379.8587
ENSG00000205937homo_sapiensENSP0000031585984.262374.4262danio_rerioENSDARP0000013156590.812780.212
ENSG00000205937homo_sapiensENSP0000031585984.262374.4262danio_rerioENSDARP0000014484290.812780.212
ENSG00000205937homo_sapiensENSP0000031585974.098465.5738carassius_auratusENSCARP0000007067975.083166.4452
ENSG00000205937homo_sapiensENSP0000031585976.721367.541carassius_auratusENSCARP0000007004875.728266.6667
ENSG00000205937homo_sapiensENSP0000031585975.08265.5738carassius_auratusENSCARP0000000704077.891268.0272
ENSG00000205937homo_sapiensENSP0000031585983.278775.082astyanax_mexicanusENSAMXP0000002802089.752680.9187
ENSG00000205937homo_sapiensENSP0000031585978.032867.541astyanax_mexicanusENSAMXP0000004700473.456863.5802
ENSG00000205937homo_sapiensENSP0000031585985.573876.3934ictalurus_punctatusENSIPUP0000001731485.294176.1438
ENSG00000205937homo_sapiensENSP0000031585955.409846.5574esox_luciusENSELUP0000003585266.274555.6863
ENSG00000205937homo_sapiensENSP0000031585983.934475.4098electrophorus_electricusENSEEEP0000004294386.779777.9661
ENSG00000205937homo_sapiensENSP0000031585976.393467.8689oncorhynchus_kisutchENSOKIP0000506124287.265977.5281
ENSG00000205937homo_sapiensENSP0000031585971.147562.9508oncorhynchus_kisutchENSOKIP0000511511486.111176.1905
ENSG00000205937homo_sapiensENSP0000031585971.803359.6721oncorhynchus_kisutchENSOKIP0000509744661.002850.6964
ENSG00000205937homo_sapiensENSP0000031585944.91839.3443oncorhynchus_mykissENSOMYP0000007311880.588270.5882
ENSG00000205937homo_sapiensENSP0000031585968.524658.0328oncorhynchus_mykissENSOMYP0000000767159.039550
ENSG00000205937homo_sapiensENSP0000031585968.524658.0328oncorhynchus_mykissENSOMYP0000000703459.039550
ENSG00000205937homo_sapiensENSP0000031585949.836142.623salmo_salarENSSSAP0000014565074.146363.4146
ENSG00000205937homo_sapiensENSP0000031585983.934474.7541salmo_salarENSSSAP0000000812278.287569.7248
ENSG00000205937homo_sapiensENSP0000031585981.639373.1148salmo_salarENSSSAP0000003632184.121675.3378
ENSG00000205937homo_sapiensENSP0000031585982.950870.4918salmo_salarENSSSAP0000007891074.852163.6095
ENSG00000205937homo_sapiensENSP0000031585983.278770.8197salmo_truttaENSSTUP0000006823475.147963.9053
ENSG00000205937homo_sapiensENSP0000031585982.622973.7705salmo_truttaENSSTUP0000002289181.553472.8155
ENSG00000205937homo_sapiensENSP0000031585981.967273.7705salmo_truttaENSSTUP0000009608589.285780.3571
ENSG00000205937homo_sapiensENSP0000031585966.229556.3934gadus_morhuaENSGMOP0000000156975.092963.9405
ENSG00000205937homo_sapiensENSP0000031585973.442664.918fundulus_heteroclitusENSFHEP0000001036376.450567.5768
ENSG00000205937homo_sapiensENSP0000031585981.967274.4262poecilia_reticulataENSPREP0000000254089.285781.0714
ENSG00000205937homo_sapiensENSP0000031585981.639374.0984xiphophorus_maculatusENSXMAP0000000483489.247381.0036
ENSG00000205937homo_sapiensENSP000003158598072.1311oryzias_latipesENSORLP0000003814889.377380.5861
ENSG00000205937homo_sapiensENSP0000031585978.688570.4918cyclopterus_lumpusENSCLMP0000504800786.330977.3381
ENSG00000205937homo_sapiensENSP0000031585974.754165.9016cyclopterus_lumpusENSCLMP0000503312879.442570.0348
ENSG00000205937homo_sapiensENSP0000031585981.311573.4426oreochromis_niloticusENSONIP0000003008689.208680.5755
ENSG00000205937homo_sapiensENSP0000031585980.327972.7869oreochromis_niloticusENSONIP0000002471188.768180.4348
ENSG00000205937homo_sapiensENSP0000031585980.983673.4426haplochromis_burtoniENSHBUP0000000131688.848980.5755
ENSG00000205937homo_sapiensENSP0000031585980.655773.4426haplochromis_burtoniENSHBUP0000001543588.489280.5755
ENSG00000205937homo_sapiensENSP0000031585971.475463.6066astatotilapia_callipteraENSACLP0000003176582.575873.4848
ENSG00000205937homo_sapiensENSP0000031585974.098464.5902astatotilapia_callipteraENSACLP0000003843475.838966.1074
ENSG00000205937homo_sapiensENSP0000031585962.62352.459sparus_aurataENSSAUP0001005987874.90262.7451
ENSG00000205937homo_sapiensENSP0000031585984.262376.0656sparus_aurataENSSAUP0001004469789.54780.8362
ENSG00000205937homo_sapiensENSP0000031585936.721333.1148lates_calcariferENSLCAP0001003584972.727365.5844
ENSG00000205937homo_sapiensENSP0000031585983.934475.7377lates_calcariferENSLCAP0001005992989.510580.7692
ENSG00000205937homo_sapiensENSP0000031585988.852581.6393xenopus_tropicalisENSXETP0000007603585.220178.3019
ENSG00000205937homo_sapiensENSP0000031585967.213163.2787chrysemys_picta_belliiENSCPBP0000000022698.086192.3445
ENSG00000205937homo_sapiensENSP0000031585998.360794.0984sphenodon_punctatusENSSPUP0000002159797.719993.4853
ENSG00000205937homo_sapiensENSP0000031585998.688594.7541crocodylus_porosusENSCPRP0000500095798.045694.1368
ENSG00000205937homo_sapiensENSP0000031585997.377192.459laticauda_laticaudataENSLLTP0000000539296.742791.8567
ENSG00000205937homo_sapiensENSP0000031585997.377192.1311notechis_scutatusENSNSUP0000000132196.742791.5309
ENSG00000205937homo_sapiensENSP0000031585997.377192.7869pseudonaja_textilisENSPTXP0000000592496.742792.1824
ENSG00000205937homo_sapiensENSP0000031585993.770590.1639anas_platyrhynchos_platyrhynchosENSAPLP0000002642991.082887.5796
ENSG00000205937homo_sapiensENSP0000031585991.147588.5246gallus_gallusENSGALP0001002463897.887395.0704
ENSG00000205937homo_sapiensENSP0000031585998.360794.7541meleagris_gallopavoENSMGAP0000001038797.719994.1368
ENSG00000205937homo_sapiensENSP0000031585993.770589.5082serinus_canariaENSSCAP0000000315293.770589.5082
ENSG00000205937homo_sapiensENSP0000031585993.114889.1803parus_majorENSPMJP0000001043190.445986.6242
ENSG00000205937homo_sapiensENSP0000031585976.065670.4918anolis_carolinensisENSACAP0000000400694.693987.7551
ENSG00000205937homo_sapiensENSP0000031585972.786962.9508neolamprologus_brichardiENSNBRP0000001886782.222271.1111
ENSG00000205937homo_sapiensENSP0000031585980.655772.459neolamprologus_brichardiENSNBRP0000003082390.109980.9524
ENSG00000205937homo_sapiensENSP0000031585997.377193.1148naja_najaENSNNAP0000001600496.742792.5081
ENSG00000205937homo_sapiensENSP0000031585998.032894.4262podarcis_muralisENSPMRP0000002320497.394193.8111
ENSG00000205937homo_sapiensENSP0000031585993.770589.1803geospiza_fortisENSGFOP0000001356292.258187.7419
ENSG00000205937homo_sapiensENSP0000031585994.754189.5082taeniopygia_guttataENSTGUP0000002451980.055475.6233
ENSG00000205937homo_sapiensENSP0000031585981.639373.7705erpetoichthys_calabaricusENSECRP0000001796572.80765.7895
ENSG00000205937homo_sapiensENSP0000031585982.950875.082kryptolebias_marmoratusENSKMAP0000001215690.68182.0788
ENSG00000205937homo_sapiensENSP0000031585998.360794.0984salvator_merianaeENSSMRP0000002150897.719993.4853
ENSG00000205937homo_sapiensENSP0000031585980.655772.1311oryzias_javanicusENSOJAP0000000767187.857178.5714
ENSG00000205937homo_sapiensENSP0000031585975.737768.8525amphilophus_citrinellusENSACIP0000002673989.189281.0811
ENSG00000205937homo_sapiensENSP0000031585979.672171.4754amphilophus_citrinellusENSACIP0000001842388.686179.562
ENSG00000205937homo_sapiensENSP0000031585984.262375.4098dicentrarchus_labraxENSDLAP0000507013391.785782.1429
ENSG00000205937homo_sapiensENSP0000031585981.967273.1148dicentrarchus_labraxENSDLAP0000507064885.910776.6323
ENSG00000205937homo_sapiensENSP0000031585982.950874.4262amphiprion_perculaENSAPEP0000000902187.543378.5467
ENSG00000205937homo_sapiensENSP0000031585982.622974.0984amphiprion_perculaENSAPEP0000002709486.896677.931
ENSG00000205937homo_sapiensENSP0000031585980.983672.459oryzias_sinensisENSOSIP0000002280888.530579.2115
ENSG00000205937homo_sapiensENSP0000031585998.688593.7705pelodiscus_sinensisENSPSIP0000000653598.045693.1596
ENSG00000205937homo_sapiensENSP0000031585998.688594.0984gopherus_evgoodeiENSGEVP0000502922198.045693.4853
ENSG00000205937homo_sapiensENSP0000031585998.360793.7705chelonoidis_abingdoniiENSCABP0000000689197.719993.1596
ENSG00000205937homo_sapiensENSP0000031585983.934474.7541seriola_dumeriliENSSDUP0000001569291.428681.4286
ENSG00000205937homo_sapiensENSP0000031585984.91875.4098seriola_dumeriliENSSDUP0000000877886.333376.6667
ENSG00000205937homo_sapiensENSP0000031585984.91875.4098cottoperca_gobioENSCGOP0000002071486.622176.9231
ENSG00000205937homo_sapiensENSP0000031585999.672195.4098struthio_camelus_australisENSSCUP0000000916599.022894.7883
ENSG00000205937homo_sapiensENSP0000031585992.45988.8525anser_brachyrhynchusENSABRP0000000442896.245792.4915
ENSG00000205937homo_sapiensENSP0000031585983.606674.7541gasterosteus_aculeatusENSGACP0000001488590.747381.1388
ENSG00000205937homo_sapiensENSP0000031585976.393469.5082gasterosteus_aculeatusENSGACP0000000745980.068772.8522
ENSG00000205937homo_sapiensENSP0000031585982.950874.4262cynoglossus_semilaevisENSCSEP0000000057684.333375.6667
ENSG00000205937homo_sapiensENSP0000031585982.622974.0984cynoglossus_semilaevisENSCSEP0000002504488.111979.021
ENSG00000205937homo_sapiensENSP0000031585981.967274.4262poecilia_formosaENSPFOP0000000993689.285781.0714
ENSG00000205937homo_sapiensENSP0000031585984.262376.7213myripristis_murdjanENSMMDP0000504975889.236181.25
ENSG00000205937homo_sapiensENSP0000031585971.803364.2623myripristis_murdjanENSMMDP0000501980590.871481.3278
ENSG00000205937homo_sapiensENSP0000031585964.91857.377sander_luciopercaENSSLUP0000005365388.392978.125
ENSG00000205937homo_sapiensENSP0000031585985.901676.0656sander_luciopercaENSSLUP0000003470482.131772.7273
ENSG00000205937homo_sapiensENSP0000031585999.016495.082strigops_habroptilaENSSHBP0000500307598.371394.4625
ENSG00000205937homo_sapiensENSP0000031585982.622974.0984amphiprion_ocellarisENSAOCP000000071399080.7143
ENSG00000205937homo_sapiensENSP0000031585998.688594.4262terrapene_carolina_triunguisENSTMTP0000000360798.045693.8111
ENSG00000205937homo_sapiensENSP0000031585981.639373.4426hucho_huchoENSHHUP0000006608888.928680
ENSG00000205937homo_sapiensENSP0000031585980.983673.1148hucho_huchoENSHHUP0000004086789.169780.5054
ENSG00000205937homo_sapiensENSP0000031585981.311572.459hucho_huchoENSHHUP0000002282086.713377.2727
ENSG00000205937homo_sapiensENSP0000031585981.311572.459betta_splendensENSBSLP0000003746780.781871.987
ENSG00000205937homo_sapiensENSP0000031585980.655772.1311betta_splendensENSBSLP0000005521387.23478.0142
ENSG00000205937homo_sapiensENSP0000031585964.262358.3607betta_splendensENSBSLP0000005460392.89184.3602
ENSG00000205937homo_sapiensENSP0000031585984.262375.7377pygocentrus_nattereriENSPNAP0000003082489.54780.4878
ENSG00000205937homo_sapiensENSP0000031585983.278775.4098pygocentrus_nattereriENSPNAP0000001895791.696883.0325
ENSG00000205937homo_sapiensENSP0000031585981.967272.7869anabas_testudineusENSATEP0000000117679.113970.2532
ENSG00000205937homo_sapiensENSP0000031585981.967273.7705anabas_testudineusENSATEP0000006161987.412678.6713
ENSG00000205937homo_sapiensENSP0000031585950.163940ciona_savignyiENSCSAVP0000000217567.699153.9823
ENSG00000205937homo_sapiensENSP0000031585976.065668.5246seriola_lalandi_dorsalisENSSLDP0000002353682.562374.3772
ENSG00000205937homo_sapiensENSP0000031585981.311572.459seriola_lalandi_dorsalisENSSLDP0000002757390.510980.6569
ENSG00000205937homo_sapiensENSP0000031585964.590260labrus_bergyltaENSLBEP0000002067293.364986.7299
ENSG00000205937homo_sapiensENSP0000031585981.967272.459labrus_bergyltaENSLBEP0000003192491.575180.9524
ENSG00000205937homo_sapiensENSP0000031585950.163942.9508pundamilia_nyerereiENSPNYP0000000814468.918959.009
ENSG00000205937homo_sapiensENSP0000031585981.311573.4426pundamilia_nyerereiENSPNYP0000000073489.208680.5755
ENSG00000205937homo_sapiensENSP0000031585973.114864.918mastacembelus_armatusENSMAMP0000003140276.632368.0412
ENSG00000205937homo_sapiensENSP0000031585982.950873.4426mastacembelus_armatusENSMAMP0000003213390.357180
ENSG00000205937homo_sapiensENSP0000031585983.278774.7541stegastes_partitusENSSPAP0000001236890.714381.4286
ENSG00000205937homo_sapiensENSP0000031585976.721369.1803stegastes_partitusENSSPAP0000000705090.697781.7829
ENSG00000205937homo_sapiensENSP0000031585959.016454.0984oncorhynchus_tshawytschaENSOTSP0000508050989.108981.6832
ENSG00000205937homo_sapiensENSP0000031585965.573856.7213oncorhynchus_tshawytschaENSOTSP0000504143577.519467.0543
ENSG00000205937homo_sapiensENSP0000031585981.639373.7705acanthochromis_polyacanthusENSAPOP0000002902590.545581.8182
ENSG00000205937homo_sapiensENSP0000031585982.950873.4426acanthochromis_polyacanthusENSAPOP0000001442879.559770.4403
ENSG00000205937homo_sapiensENSP0000031585999.016495.082aquila_chrysaetos_chrysaetosENSACCP0002001853898.371394.4625
ENSG00000205937homo_sapiensENSP0000031585982.295175.4098nothobranchius_furzeriENSNFUP0001500765189.964282.4373
ENSG00000205937homo_sapiensENSP0000031585983.278775.4098cyprinodon_variegatusENSCVAP0000000897188.194479.8611
ENSG00000205937homo_sapiensENSP0000031585965.573861.6393denticeps_clupeoidesENSDCDP0000001029793.896788.2629
ENSG00000205937homo_sapiensENSP0000031585985.573875.7377denticeps_clupeoidesENSDCDP0000003375490.62580.2083
ENSG00000205937homo_sapiensENSP0000031585982.622973.7705larimichthys_croceaENSLCRP0000501826079.746871.2025
ENSG00000205937homo_sapiensENSP0000031585981.639370.1639takifugu_rubripesENSTRUP0000007590568.032858.4699
ENSG00000205937homo_sapiensENSP0000031585982.950873.1148takifugu_rubripesENSTRUP0000002157989.716379.078
ENSG00000205937homo_sapiensENSP0000031585991.475488.8525ficedula_albicollisENSFALP0000000506798.239495.4225
ENSG00000205937homo_sapiensENSP0000031585971.803361.9672hippocampus_comesENSHCOP0000000157285.21473.5409
ENSG00000205937homo_sapiensENSP0000031585982.950873.4426hippocampus_comesENSHCOP0000001925988.771978.5965
ENSG00000205937homo_sapiensENSP0000031585984.262375.7377cyprinus_carpio_carpioENSCCRP0000015439372.804565.4391
ENSG00000205937homo_sapiensENSP0000031585984.262375.4098cyprinus_carpio_carpioENSCCRP0000015193788.316279.0378
ENSG00000205937homo_sapiensENSP0000031585973.770569.8361coturnix_japonicaENSCJPP0000502321697.402692.2078
ENSG00000205937homo_sapiensENSP0000031585981.967274.4262poecilia_latipinnaENSPLAP0000000708289.285781.0714
ENSG00000205937homo_sapiensENSP0000031585984.590275.082sinocyclocheilus_grahamiENSSGRP000000508738676.3333
ENSG00000205937homo_sapiensENSP0000031585983.606675.082sinocyclocheilus_grahamiENSSGRP0000009062787.93178.9655
ENSG00000205937homo_sapiensENSP0000031585980.327973.1148maylandia_zebraENSMZEP0000500821688.768180.7971
ENSG00000205937homo_sapiensENSP0000031585981.311573.4426maylandia_zebraENSMZEP0000501696689.208680.5755
ENSG00000205937homo_sapiensENSP0000031585976.065667.2131tetraodon_nigroviridisENSTNIP0000001021782.562372.9537
ENSG00000205937homo_sapiensENSP0000031585983.278774.0984tetraodon_nigroviridisENSTNIP0000001264088.501778.7456
ENSG00000205937homo_sapiensENSP0000031585974.426268.1967paramormyrops_kingsleyaeENSPKIP0000001026871.608865.6151
ENSG00000205937homo_sapiensENSP0000031585985.245976.0656paramormyrops_kingsleyaeENSPKIP0000000765091.549381.6901
ENSG00000205937homo_sapiensENSP0000031585976.721367.2131scleropages_formosusENSSFOP0001503574884.782674.2754
ENSG00000205937homo_sapiensENSP0000031585972.786966.8852scleropages_formosusENSSFOP0001503013487.058880
ENSG00000205937homo_sapiensENSP0000031585976.065667.2131leptobrachium_leishanenseENSLLEP0000004719290.62580.0781
ENSG00000205937homo_sapiensENSP0000031585982.295174.4262scophthalmus_maximusENSSMAP0000004867190.613781.9495
ENSG00000205937homo_sapiensENSP0000031585953.442649.1803oryzias_melastigmaENSOMEP0000000756782.741176.1421
ENSG00000205937homo_sapiensENSP000003158598072.1311oryzias_melastigmaENSOMEP0000000826587.769879.1367

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000184involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay2IDA,IMPHomo_sapiens(9606)Process
GO:0000381involved_in regulation of alternative mRNA splicing, via spliceosome1IMPHomo_sapiens(9606)Process
GO:0000398involved_in mRNA splicing, via spliceosome1IBAHomo_sapiens(9606)Process
GO:0003723enables RNA binding2HDA,IDAHomo_sapiens(9606)Function
GO:0003730enables mRNA 3-UTR binding1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005654is_active_in nucleoplasm3IBA,IDA,TASHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0006351involved_in DNA-templated transcription1TASHomo_sapiens(9606)Process
GO:0008380involved_in RNA splicing1TASHomo_sapiens(9606)Process
GO:0016607located_in nuclear speck1IEAHomo_sapiens(9606)Component
GO:0043065involved_in positive regulation of apoptotic process1IDAHomo_sapiens(9606)Process
GO:0048025involved_in negative regulation of mRNA splicing, via spliceosome1IDAHomo_sapiens(9606)Process
GO:0061574part_of ASAP complex2IBA,IDAHomo_sapiens(9606)Component

Expression