Ensembl ID ENSG00000205937 Gene ID 10921 Accession 10080
Gene Symbol RNPS1 Alias E5.1 Full Name RNA binding protein with serine rich domain 1
Position 16 : 2253116 - 2268397 Length 15282 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

ENSG00000205937 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000205937 RNPS1 0.28 1.44e-11 KIRC
ENSG00000205937 RNPS1 0.75 2.42e-57 BRCA
ENSG00000205937 RNPS1 0.62 1.90e-24 COAD
ENSG00000205937 RNPS1 0.75 3.46e-19 KICH
ENSG00000205937 RNPS1 0.76 1.97e-36 LUSC
ENSG00000205937 RNPS1 0.57 3.90e-17 KIRP
ENSG00000205937 RNPS1 0.59 7.81e-29 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000205937 RNPS1 tumor 11477570
ENSG00000205937 RNPS1 cancer 30809433
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000205937 RNPS1 MESO 0.00029 high
ENSG00000205937 RNPS1 SARC 0.05 high
ENSG00000205937 RNPS1 STAD 0.0087 low
ENSG00000205937 RNPS1 CHOL 0.046 high
ENSG00000205937 RNPS1 UCEC 0.0027 high
ENSG00000205937 RNPS1 THCA 0.044 high
ENSG00000205937 RNPS1 ACC 0.017 high
ENSG00000205937 RNPS1 HNSC 0.022 high
ENSG00000205937 RNPS1 READ 0.0085 low
ENSG00000205937 RNPS1 KIRP 0.00023 high
ENSG00000205937 RNPS1 KICH 0.013 low
ENSG00000205937 RNPS1 PCPG 0.00077 low
ENSG00000205937 RNPS1 THYM 0.038 low
ENSG00000205937 RNPS1 BRCA 0.034 low
ENSG00000205937 RNPS1 UCS 0.02 high
ENSG00000205937 RNPS1 PRAD 0.047 high
ENSG00000205937 RNPS1 BLCA 0.044 low
ENSG00000205937 RNPS1 CESC 0.0036 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000205937 RNPS1 LUSC Del 1.812469 0.080821 0.348961 0.369261
ENSG00000205937 RNPS1 BLCA Del 6.881578 0.152314 0.386475 0.414216
ENSG00000205937 RNPS1 STAD Del 1.504249 0.072177 0.382577 0.244898