Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerSARS-COV-OC43FlavivirusesSARS-COV-2SINVDengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq DataSet_02_41 DataSet_02_42

Description

Ensembl ID ENSG00000204842 Gene ID 6311 Accession 10555
Symbol ATXN2 Alias ATX2;SCA2;TNRC13 Full Name ataxin 2
Status Confidence Length 156192 bases Strand Minus strand
Position 12 : 111443485 - 111599676 RNA binding domain LsmAD , PAM2 , SM-ATX
Summary This gene belongs to a group of genes that is associated with microsatellite-expansion diseases, a class of neurological and neuromuscular disorders caused by expansion of short stretches of repetitive DNA. The protein encoded by this gene has two globular domains near the N-terminus, one of which contains a clathrin-mediated trans-Golgi signal and an endoplasmic reticulum exit signal. The encoded cytoplasmic protein localizes to the endoplasmic reticulum and plasma membrane, is involved in endocytosis, and modulates mTOR signals, modifying ribosomal translation and mitochondrial function. The N-terminal region of the protein contains a polyglutamine tract of 14-31 residues that can be expanded in the pathogenic state to 32-200 residues. Intermediate length expansions of this tract increase susceptibility to amyotrophic lateral sclerosis, while long expansions of this tract result in spinocerebellar ataxia-2, an autosomal-dominantly inherited, neurodegenerative disorder. Genome-wide association studies indicate that loss-of-function mutations in this gene may be associated with susceptibility to type I diabetes, obesity and hypertension. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000500090 SM-ATX PF14438 6e-21 1
ENSP00000500090 LsmAD PF06741 1.6e-15 2
ENSP00000446512 SM-ATX PF14438 1.6e-20 1
ENSP00000446512 PAM2 PF07145 1.3e-05 2
ENSP00000446512 LsmAD PF06741 1.4e-14 3
ENSP00000496279 SM-ATX PF14438 2e-20 1
ENSP00000496279 PAM2 PF07145 1.5e-05 2
ENSP00000496279 LsmAD PF06741 1.6e-14 3
ENSP00000493897 SM-ATX PF14438 2.1e-20 1
ENSP00000493897 PAM2 PF07145 1.5e-05 2
ENSP00000493897 LsmAD PF06741 1.7e-14 3
ENSP00000500313 SM-ATX PF14438 2.3e-20 1
ENSP00000500313 PAM2 PF07145 1.7e-05 2
ENSP00000500313 LsmAD PF06741 5.3e-15 3
ENSP00000373805 SM-ATX PF14438 2.4e-20 1
ENSP00000373805 PAM2 PF07145 1.7e-05 2
ENSP00000373805 LsmAD PF06741 5.7e-15 3
ENSP00000476504 SM-ATX PF14438 2.6e-20 1
ENSP00000476504 PAM2 PF07145 1.9e-05 2
ENSP00000476504 LsmAD PF06741 6.3e-15 3
ENSP00000500649 SM-ATX PF14438 2.6e-20 1
ENSP00000500649 PAM2 PF07145 1.9e-05 2
ENSP00000500649 LsmAD PF06741 6.3e-15 3
ENSP00000500925 SM-ATX PF14438 2.6e-20 1
ENSP00000500925 PAM2 PF07145 1.9e-05 2
ENSP00000500925 LsmAD PF06741 6.3e-15 3
ENSP00000496055 SM-ATX PF14438 2.6e-20 1
ENSP00000496055 PAM2 PF07145 1.9e-05 2
ENSP00000496055 LsmAD PF06741 6.3e-15 3
ENSP00000500766 SM-ATX PF14438 2.7e-20 1
ENSP00000500766 PAM2 PF07145 1.9e-05 2
ENSP00000500766 LsmAD PF06741 6.4e-15 3
ENSP00000494663 SM-ATX PF14438 2.7e-20 1
ENSP00000494663 PAM2 PF07145 1.9e-05 2
ENSP00000494663 LsmAD PF06741 6.4e-15 3
ENSP00000500646 SM-ATX PF14438 2.7e-20 1
ENSP00000500646 PAM2 PF07145 1.9e-05 2
ENSP00000500646 LsmAD PF06741 6.5e-15 3
ENSP00000446576 SM-ATX PF14438 3.2e-20 1
ENSP00000446576 PAM2 PF07145 2.1e-05 2
ENSP00000446576 LsmAD PF06741 7.7e-15 3
ENSP00000445583 SM-ATX PF14438 6.7e-20 1
ENSP00000445583 PAM2 PF07145 1.7e-05 2
ENSP00000445583 LsmAD PF06741 7.4e-15 3
ENSP00000474442 PAM2 PF07145 9.5e-07 1
ENSP00000373806 PAM2 PF07145 2.2e-06 1
ENSP00000447225 PAM2 PF07145 1.4e-05 1
ENSP00000447225 LsmAD PF06741 5.6e-15 2
ENSP00000439338 PAM2 PF07145 1.6e-05 1
ENSP00000439338 LsmAD PF06741 6.6e-15 2
ENSP00000481448 PAM2 PF07145 1.6e-05 1
ENSP00000481448 LsmAD PF06741 6.6e-15 2
ENSP00000448640 LsmAD PF06741 1.1e-15 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
ATXN2-227 ENST00000642389 4438 1158aa ENSP00000496055
ATXN2-202 ENST00000389154 1794 424aa ENSP00000373806
ATXN2-238 ENST00000672613 4341 1153aa ENSP00000500649
ATXN2-241 ENST00000673436 4347 1155aa ENSP00000500925
ATXN2-229 ENST00000643669 4380 1166aa ENSP00000494663
ATXN2-225 ENST00000608853 4376 1153aa ENSP00000476504
ATXN2-201 ENST00000389153 3941 1087aa ENSP00000373805
ATXN2-209 ENST00000483311 4159 835aa ENSP00000446512
ATXN2-237 ENST00000672335 3797 No protein -
ATXN2-210 ENST00000484991 793 No protein -
ATXN2-234 ENST00000647445 1263 298aa ENSP00000493566
ATXN2-208 ENST00000482777 4369 No protein -
ATXN2-211 ENST00000492467 2996 908aa ENSP00000447225
ATXN2-243 ENST00000673557 3926 1167aa ENSP00000500766
ATXN2-240 ENST00000673283 3526 1065aa ENSP00000500313
ATXN2-239 ENST00000673273 1525 317aa ENSP00000500376
ATXN2-242 ENST00000673449 3754 1178aa ENSP00000500646
ATXN2-213 ENST00000535949 3205 1006aa ENSP00000439338
ATXN2-214 ENST00000542287 3443 1073aa ENSP00000445583
ATXN2-206 ENST00000475132 610 119aa ENSP00000474645
ATXN2-220 ENST00000550844 3104 196aa ENSP00000447741
ATXN2-204 ENST00000468920 568 No protein -
ATXN2-228 ENST00000643474 765 255aa ENSP00000496329
ATXN2-230 ENST00000643694 447 149aa ENSP00000495833
ATXN2-222 ENST00000551551 1256 No protein -
ATXN2-221 ENST00000550889 1703 No protein -
ATXN2-232 ENST00000645162 1444 No protein -
ATXN2-223 ENST00000551755 695 107aa ENSP00000474442
ATXN2-231 ENST00000644883 4674 957aa ENSP00000496279
ATXN2-233 ENST00000647305 3639 968aa ENSP00000493897
ATXN2-212 ENST00000495342 813 No protein -
ATXN2-224 ENST00000552323 430 No protein -
ATXN2-215 ENST00000546483 2098 No protein -
ATXN2-219 ENST00000550236 704 235aa ENSP00000448640
ATXN2-235 ENST00000671792 1239 347aa ENSP00000500090
ATXN2-203 ENST00000392645 2842 No protein -
ATXN2-236 ENST00000672105 2134 No protein -
ATXN2-207 ENST00000481331 381 No protein -
ATXN2-205 ENST00000471866 836 No protein -
ATXN2-217 ENST00000549455 568 No protein -
ATXN2-216 ENST00000548492 556 No protein -
ATXN2-218 ENST00000550104 4648 1313aa ENSP00000446576
ATXN2-226 ENST00000616825 4575 1006aa ENSP00000481448

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
47166Blood Pressure9.3027860E-010-
47220Blood Pressure1.6434877E-014-
47242Blood Pressure4.1816894E-014-
47252Blood Pressure4.3116197E-014-
47253Blood Pressure3.4344220E-012-
47319Arterial Pressure1.7430628E-011-
47333Arterial Pressure3.9127351E-011-
47338Arterial Pressure3.8098464E-011-
47342Arterial Pressure1.8210550E-009-
59324Blood Pressure1.0520000E-02027618452
59344Blood Pressure5.1010000E-01927618452
59357Blood Pressure2.2230000E-02027618452
59456Blood Pressure9.3519280E-020-
59480Blood Pressure1.3764519E-018-
59483Blood Pressure3.0140867E-016-
59562Blood Pressure4.3698678E-022-
59587Blood Pressure6.7684277E-020-
59590Blood Pressure4.8229821E-018-
59665Blood Pressure2.0929512E-018-
59685Blood Pressure1.3610822E-017-
59688Blood Pressure4.8045734E-014-
59768Blood Pressure5.2930360E-020-
59789Blood Pressure1.2441670E-018-
59792Blood Pressure6.9094673E-016-
59836Hypertension2.7643760E-008-
59856Hypertension6.9467264E-007-
59858Hypertension2.9578814E-006-
59926Hypertension2.5959074E-009-
59945Hypertension9.1919744E-007-
59946Hypertension7.7411636E-007-
60031Arterial Pressure2.8330700E-021-
60053Arterial Pressure8.6825579E-021-
60056Arterial Pressure6.0952178E-017-
60139Arterial Pressure1.1113761E-023-
60161Arterial Pressure5.3770299E-022-
60164Arterial Pressure3.8833927E-019-
60867Hemoglobins1E-1119862010
61055Hematocrit1E-1219862010
62625Tetralogy of Fallot8E-1123297363
64643Blood Pressure3E-1819430483
67360Body Mass Index1E-625673413
68752Vitiligo4E-1822561518
70334Celiac Disease7E-2120190752
73683Myocardial Infarction3E-1126343387
75868Blood Pressure5E-726390057
79718Cholesterol, LDL2E-920686565
80971Liver Cirrhosis, Biliary3E-826394269
83114Coronary Disease3E-1024262325
83115Stroke3E-1024262325
83551Cholesterol7E-1220686565
84117Peripheral Arterial Disease6E-725009551
84164Hematocrit1E-828017375
86365Crohn Disease7E-826192919
86466Inflammatory Bowel Diseases1E-826192919
87665Lupus Erythematosus, Systemic4E-926502338
87827Hypothyroidism1E-2627182965
89760Glaucoma, Open-Angle9E-1026752265
90506Inflammatory Bowel Diseases2E-928067908
94196Body Mass Index1E-625673413
94850Celiac Disease8E-818311140
96333Lupus Erythematosus, Systemic9E-827399966
97571thyroid microsomal antibodies1E-724586183
98129Cholesterol, LDL1E-1124097068
98229thyroid microsomal antibodies1E-924586183
98800Lupus Erythematosus, Systemic6E-1026502338
99271Coronary Disease4E-1424262325
99272Stroke4E-1424262325
99804Cholesterol2E-1624097068
100929Corneal Pachymetry2E-1321060863
103997Autoimmune Diseases3E-1921383967
104176Renal Insufficiency, Chronic4E-1120383146
104177Cystatin C4E-1120383146
104371Blood Pressure1E-826390057
104503Arterial Pressure7E-2021909110
104668Uric Acid7E-1223263486
104781Crohn Disease7E-728067908
105909Adenocarcinoma of lung5E-627197191
105910Breast Neoplasms5E-627197191
105911Carcinoma, Non-Small-Cell Lung5E-627197191
105912Lung Neoplasms5E-627197191
105913Ovarian Neoplasms5E-627197191
105914Prostatic Neoplasms5E-627197191
105915Colorectal Neoplasms5E-627197191
105916Carcinoma, Endometrioid5E-627197191

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000204842homo_sapiensENSP0000033871855.255840.3721homo_sapiensENSP0000050092551.428637.5758

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000204842homo_sapiensENSP0000050092598.96198.6147nomascus_leucogenysENSNLEP0000000062291.513291.193
ENSG00000204842homo_sapiensENSP0000050092594.285793.7662pan_paniscusENSPPAP0000000976187.259686.7788
ENSG00000204842homo_sapiensENSP0000050092596.7196.1039pongo_abeliiENSPPYP0000003718485.072484.5392
ENSG00000204842homo_sapiensENSP0000050092599.047698.8745pan_troglodytesENSPTRP0000005730899.133498.9601
ENSG00000204842homo_sapiensENSP0000050092593.333392.6407gorilla_gorillaENSGGOP0000002519396.078495.3654
ENSG00000204842homo_sapiensENSP0000050092588.917784.0693ornithorhynchus_anatinusENSOANP0000004387178.098973.8403
ENSG00000204842homo_sapiensENSP0000050092587.792282.7706sarcophilus_harrisiiENSSHAP0000003361888.713983.6395
ENSG00000204842homo_sapiensENSP0000050092566.147262.5974notamacropus_eugeniiENSMEUP0000001118172.485868.5958
ENSG00000204842homo_sapiensENSP0000050092565.36864.1558choloepus_hoffmanniENSCHOP0000000379775.575674.1742
ENSG00000204842homo_sapiensENSP0000050092596.017394.1991dasypus_novemcinctusENSDNOP0000001217585.902484.2758
ENSG00000204842homo_sapiensENSP0000050092563.376660.8658erinaceus_europaeusENSEEUP0000001338468.475265.7624
ENSG00000204842homo_sapiensENSP0000050092578.96176.7965echinops_telfairiENSETEP0000000425169.565267.6583
ENSG00000204842homo_sapiensENSP0000050092597.748997.316callithrix_jacchusENSCJAP0000002179586.513486.1303
ENSG00000204842homo_sapiensENSP0000050092598.35598.0087cercocebus_atysENSCATP0000000555091.760991.4378
ENSG00000204842homo_sapiensENSP0000050092596.450295.7576macaca_fascicularisENSMFAP0000004561696.617595.9237
ENSG00000204842homo_sapiensENSP0000050092598.35598.0952macaca_mulattaENSMMUP0000004513685.413585.188
ENSG00000204842homo_sapiensENSP0000050092598.095297.8355macaca_nemestrinaENSMNEP0000002457893.097892.8513
ENSG00000204842homo_sapiensENSP0000050092598.614798.4416papio_anubisENSPANP0000004968687.146186.9931
ENSG00000204842homo_sapiensENSP0000050092590.476290.3896mandrillus_leucophaeusENSMLEP0000000572097.390597.2973
ENSG00000204842homo_sapiensENSP0000050092584.069383.1169tursiops_truncatusENSTTRP0000000089776.456775.5906
ENSG00000204842homo_sapiensENSP0000050092589.004388.1385vulpes_vulpesENSVVUP0000002192596.164695.2292
ENSG00000204842homo_sapiensENSP0000050092594.199190.8225mus_spretusMGP_SPRETEiJ_P007316787.812884.6651
ENSG00000204842homo_sapiensENSP0000050092596.883195.4113equus_asinusENSEASP0000501756485.944784.639
ENSG00000204842homo_sapiensENSP0000050092595.67193.9394capra_hircusENSCHIP0000000919485.065483.5258
ENSG00000204842homo_sapiensENSP0000050092591.601789.9567loxodonta_africanaENSLAFP0000000624898.510296.7412
ENSG00000204842homo_sapiensENSP0000050092595.584493.9394panthera_leoENSPLOP0000000934385.053983.5901
ENSG00000204842homo_sapiensENSP0000050092593.852892.5541ailuropoda_melanoleucaENSAMEP0000003910892.570491.2895
ENSG00000204842homo_sapiensENSP0000050092596.536894.7186bos_indicus_hybridENSBIXP0000503957986.03484.4136
ENSG00000204842homo_sapiensENSP0000050092589.870187.0996oryctolagus_cuniculusENSOCUP0000001717091.373288.5563
ENSG00000204842homo_sapiensENSP0000050092596.363694.9784equus_caballusENSECAP0000002612294.965993.6007
ENSG00000204842homo_sapiensENSP0000050092596.103994.5455canis_lupus_familiarisENSCAFP0084504175384.992383.6141
ENSG00000204842homo_sapiensENSP0000050092595.238193.6797panthera_pardusENSPPRP0000000870296.660895.0791
ENSG00000204842homo_sapiensENSP0000050092590.649489.6104marmota_marmota_marmotaENSMMMP0000000551193.149592.0818
ENSG00000204842homo_sapiensENSP0000050092595.757694.1126balaenoptera_musculusENSBMSP0001001992185.076983.6154
ENSG00000204842homo_sapiensENSP0000050092595.064993.0736cavia_porcellusENSCPOP0000000125684.396682.6287
ENSG00000204842homo_sapiensENSP0000050092593.766291.8615felis_catusENSFCAP0000004051792.406190.529
ENSG00000204842homo_sapiensENSP0000050092595.930794.5455ursus_americanusENSUAMP0000003318096.937995.5381
ENSG00000204842homo_sapiensENSP0000050092586.493581.8182monodelphis_domesticaENSMODP0000005255794.691989.5735
ENSG00000204842homo_sapiensENSP0000050092591.601790.3896bison_bison_bisonENSBBBP0000002213482.850481.7541
ENSG00000204842homo_sapiensENSP0000050092596.450294.8918monodon_monocerosENSMMNP0001500416085.298683.9204
ENSG00000204842homo_sapiensENSP0000050092595.844293.9394sus_scrofaENSSSCP0000003118282.921381.2734
ENSG00000204842homo_sapiensENSP0000050092589.783589.2641microcebus_murinusENSMICP0000001759397.279596.7167
ENSG00000204842homo_sapiensENSP0000050092589.264187.5325octodon_degusENSODEP0000001459598.097196.1941
ENSG00000204842homo_sapiensENSP0000050092518.095217.4026jaculus_jaculusENSJJAP0000002288089.316285.8974
ENSG00000204842homo_sapiensENSP0000050092594.891893.0736ovis_aries_rambouilletENSOARP0002002264785.75984.1158
ENSG00000204842homo_sapiensENSP0000050092587.272786.3203ursus_maritimusENSUMAP0000000967993.680392.658
ENSG00000204842homo_sapiensENSP0000050092585.800983.5498ochotona_princepsENSOPRP0000001333393.844791.3826
ENSG00000204842homo_sapiensENSP0000050092596.450294.8918delphinapterus_leucasENSDLEP0000001074185.36483.9847
ENSG00000204842homo_sapiensENSP0000050092587.878886.7533physeter_catodonENSPCTP0000502675794.243393.0362
ENSG00000204842homo_sapiensENSP0000050092594.112690.7359mus_caroliMGP_CAROLIEiJ_P007047884.328981.3033
ENSG00000204842homo_sapiensENSP0000050092594.02690.5628mus_musculusENSMUSP0000005671584.447981.3375
ENSG00000204842homo_sapiensENSP0000050092583.722980.1732dipodomys_ordiiENSDORP0000002759692.359188.4432
ENSG00000204842homo_sapiensENSP0000050092589.69788.8312mustela_putorius_furoENSMPUP0000000219097.185796.2477
ENSG00000204842homo_sapiensENSP0000050092596.623495.7576aotus_nancymaaeENSANAP0000000905686.377785.6037
ENSG00000204842homo_sapiensENSP0000050092590.389690.1299saimiri_boliviensis_boliviensisENSSBOP0000003090697.297397.0177
ENSG00000204842homo_sapiensENSP0000050092585.454584.2424vicugna_pacosENSVPAP0000000551492.589191.2758
ENSG00000204842homo_sapiensENSP0000050092598.874598.7879chlorocebus_sabaeusENSCSAP0000001545699.218199.1312
ENSG00000204842homo_sapiensENSP0000050092579.653778.2684tupaia_belangeriENSTBEP0000000176385.981384.486
ENSG00000204842homo_sapiensENSP0000050092556.103954.1126mesocricetus_auratusENSMAUP0000000621798.181894.697
ENSG00000204842homo_sapiensENSP0000050092596.103994.9784phocoena_sinusENSPSNP0000000672285.714384.7104
ENSG00000204842homo_sapiensENSP0000050092597.229496.0173camelus_dromedariusENSCDRP0000501244096.893995.6859
ENSG00000204842homo_sapiensENSP0000050092592.034691.1688carlito_syrichtaENSTSYP0000002474280.959680.198
ENSG00000204842homo_sapiensENSP0000050092590.909189.7835panthera_tigris_altaicaENSPTIP0000002536091.145890.0174
ENSG00000204842homo_sapiensENSP0000050092592.034688.3983rattus_norvegicusENSRNOP0000009561676.091673.0852
ENSG00000204842homo_sapiensENSP0000050092596.190594.7186prolemur_simusENSPSMP0000003746985.924284.6094
ENSG00000204842homo_sapiensENSP0000050092576.190573.2467microtus_ochrogasterENSMOCP0000000570794.827691.1638
ENSG00000204842homo_sapiensENSP0000050092569.870167.7922sorex_araneusENSSARP0000000574776.71174.4297
ENSG00000204842homo_sapiensENSP0000050092590.562887.7056peromyscus_maniculatus_bairdiiENSPEMP0000001596581.400878.8327
ENSG00000204842homo_sapiensENSP0000050092591.688390.4762bos_mutusENSBMUP0000002851580.901579.8319
ENSG00000204842homo_sapiensENSP0000050092590.129987.2727mus_spicilegusENSMSIP0000001453593.783890.8108
ENSG00000204842homo_sapiensENSP0000050092591.774987.7056cricetulus_griseus_chok1gshdENSCGRP0000102480383.662279.9526
ENSG00000204842homo_sapiensENSP0000050092590.216588.8312pteropus_vampyrusENSPVAP0000001243280.153878.9231
ENSG00000204842homo_sapiensENSP0000050092590.476289.1775myotis_lucifugusENSMLUP0000001419397.299895.9032
ENSG00000204842homo_sapiensENSP0000050092585.97481.4719vombatus_ursinusENSVURP0001003140389.620984.9278
ENSG00000204842homo_sapiensENSP0000050092596.103994.3723rhinolophus_ferrumequinumENSRFEP0001001339496.858695.1134
ENSG00000204842homo_sapiensENSP0000050092596.103994.8918neovison_visonENSNVIP0000002123685.450384.3726
ENSG00000204842homo_sapiensENSP0000050092595.844293.9394bos_taurusENSBTAP0000002961884.246682.5723
ENSG00000204842homo_sapiensENSP0000050092593.939491.9481heterocephalus_glaber_femaleENSHGLP0000003046083.848582.0711
ENSG00000204842homo_sapiensENSP0000050092589.350689.2641rhinopithecus_bietiENSRBIP0000003077897.175197.081
ENSG00000204842homo_sapiensENSP0000050092589.437288.658canis_lupus_dingoENSCAFP0002002155898.568797.7099
ENSG00000204842homo_sapiensENSP0000050092596.277194.632sciurus_vulgarisENSSVLP0000500854486.134884.6631
ENSG00000204842homo_sapiensENSP0000050092585.281480.7792phascolarctos_cinereusENSPCIP0000000855893.631288.6882
ENSG00000204842homo_sapiensENSP0000050092556.883156.2771procavia_capensisENSPCAP0000000404150.19149.6562
ENSG00000204842homo_sapiensENSP0000050092518.268417.6623nannospalax_galiliENSNGAP0000001868290.170987.1795
ENSG00000204842homo_sapiensENSP0000050092596.277194.4589bos_grunniensENSBGRP0000002344186.001584.3774
ENSG00000204842homo_sapiensENSP0000050092591.34289.7835chinchilla_lanigeraENSCLAP0000001349196.78995.1376
ENSG00000204842homo_sapiensENSP0000050092596.536894.7186cervus_hanglu_yarkandensisENSCHYP0000000475785.901484.2835
ENSG00000204842homo_sapiensENSP0000050092596.363694.1126catagonus_wagneriENSCWAP0000001254985.418383.4229
ENSG00000204842homo_sapiensENSP0000050092592.207891.0823ictidomys_tridecemlineatusENSSTOP0000003089586.585485.5285
ENSG00000204842homo_sapiensENSP0000050092596.363695.4978otolemur_garnettiiENSOGAP0000000054786.212285.4376
ENSG00000204842homo_sapiensENSP0000050092597.922197.316cebus_imitatorENSCCAP0000001716386.401885.8671
ENSG00000204842homo_sapiensENSP0000050092595.324793.7662urocitellus_parryiiENSUPAP0001000824684.627283.2437
ENSG00000204842homo_sapiensENSP0000050092596.536894.632moschus_moschiferusENSMMSP0000002861686.100484.4015
ENSG00000204842homo_sapiensENSP0000050092592.034691.4286rhinopithecus_roxellanaENSRROP0000001395684.768784.2105
ENSG00000204842homo_sapiensENSP0000050092587.878884.2424mus_pahariMGP_PahariEiJ_P005869183.333379.8851
ENSG00000204842homo_sapiensENSP0000050092595.064993.7662propithecus_coquereliENSPCOP0000002017586.117684.9412
ENSG00000204842homo_sapiensENSP0000050092529.783620.7792caenorhabditis_elegansD2045.1d.132.149522.4299
ENSG00000204842homo_sapiensENSP0000050092535.584424.7619petromyzon_marinusENSPMAP0000000793542.723529.7297
ENSG00000204842homo_sapiensENSP0000050092529.264119.0476petromyzon_marinusENSPMAP0000000506935.466923.085
ENSG00000204842homo_sapiensENSP0000050092514.545510.4762eptatretus_burgeriENSEBUP0000002113448.554934.9711
ENSG00000204842homo_sapiensENSP0000050092525.714316.1905eptatretus_burgeriENSEBUP0000000970037.738223.7611
ENSG00000204842homo_sapiensENSP0000050092554.891847.7056callorhinchus_miliiENSCMIP0000001458359.307851.5435
ENSG00000204842homo_sapiensENSP0000050092579.047670.6494latimeria_chalumnaeENSLACP0000001422984.147575.2074
ENSG00000204842homo_sapiensENSP0000050092574.545565.368lepisosteus_oculatusENSLOCP0000000957278.70269.0128
ENSG00000204842homo_sapiensENSP0000050092563.722953.7662clupea_harengusENSCHAP0000001676870.97459.8843
ENSG00000204842homo_sapiensENSP0000050092569.437259.0476danio_rerioENSDARP0000007809172.122361.3309
ENSG00000204842homo_sapiensENSP0000050092562.424252.6407carassius_auratusENSCARP0000009261569.661858.744
ENSG00000204842homo_sapiensENSP0000050092565.108254.8918carassius_auratusENSCARP0000013454470.083959.0867
ENSG00000204842homo_sapiensENSP0000050092564.32953.7662astyanax_mexicanusENSAMXP0000002993868.102756.9203
ENSG00000204842homo_sapiensENSP0000050092561.818251.6017ictalurus_punctatusENSIPUP0000002461567.935356.7079
ENSG00000204842homo_sapiensENSP0000050092566.147255.2381esox_luciusENSELUP0000002031171.069859.3488
ENSG00000204842homo_sapiensENSP0000050092556.623448.2251electrophorus_electricusENSEEEP0000004691369.797259.445
ENSG00000204842homo_sapiensENSP0000050092561.385350.7359oncorhynchus_kisutchENSOKIP0000508453271.113358.7763
ENSG00000204842homo_sapiensENSP0000050092560.865850.9957oncorhynchus_kisutchENSOKIP0000501627870.938459.4349
ENSG00000204842homo_sapiensENSP0000050092558.268448.8312oncorhynchus_mykissENSOMYP0000010322064.898754.3877
ENSG00000204842homo_sapiensENSP0000050092563.982754.2857oncorhynchus_mykissENSOMYP0000007228271.887260.9922
ENSG00000204842homo_sapiensENSP0000050092562.337752.6407salmo_salarENSSSAP0000009122270.726959.725
ENSG00000204842homo_sapiensENSP0000050092562.251151.4286salmo_salarENSSSAP0000011045171.959.4
ENSG00000204842homo_sapiensENSP0000050092563.030352.2078salmo_truttaENSSTUP0000003577270.886158.7147
ENSG00000204842homo_sapiensENSP0000050092565.36854.7186salmo_truttaENSSTUP0000006681570.560759.0654
ENSG00000204842homo_sapiensENSP0000050092564.935153.9394gadus_morhuaENSGMOP0000000793870.422558.4977
ENSG00000204842homo_sapiensENSP0000050092561.471950.1299fundulus_heteroclitusENSFHEP0000003284570.29757.3267
ENSG00000204842homo_sapiensENSP0000050092567.359356.7965poecilia_reticulataENSPREP0000002211373.120361.6541
ENSG00000204842homo_sapiensENSP0000050092564.155852.7273xiphophorus_maculatusENSXMAP0000002753371.456158.7271
ENSG00000204842homo_sapiensENSP0000050092561.991351.1688oryzias_latipesENSORLP0000003052370.82158.457
ENSG00000204842homo_sapiensENSP0000050092562.943753.8528cyclopterus_lumpusENSCLMP0000502642968.007558.1852
ENSG00000204842homo_sapiensENSP0000050092564.32953.5065oreochromis_niloticusENSONIP0000002946569.504257.811
ENSG00000204842homo_sapiensENSP0000050092564.761953.9394haplochromis_burtoniENSHBUP0000000176371.035159.1643
ENSG00000204842homo_sapiensENSP0000050092563.030352.987astatotilapia_callipteraENSACLP0000001969668.485457.5729
ENSG00000204842homo_sapiensENSP0000050092564.32953.7662sparus_aurataENSSAUP0001001795469.634558.2006
ENSG00000204842homo_sapiensENSP0000050092565.108255.2381lates_calcariferENSLCAP0001001081870.676759.9624
ENSG00000204842homo_sapiensENSP0000050092582.251174.1126xenopus_tropicalisENSXETP0000008870884.294675.9539
ENSG00000204842homo_sapiensENSP0000050092579.307475.0649chrysemys_picta_belliiENSCPBP0000000426992.900687.931
ENSG00000204842homo_sapiensENSP0000050092587.445981.7316sphenodon_punctatusENSSPUP0000001353587.521781.8024
ENSG00000204842homo_sapiensENSP0000050092585.281480.7792crocodylus_porosusENSCPRP0000501920289.464184.7411
ENSG00000204842homo_sapiensENSP0000050092543.549837.5758laticauda_laticaudataENSLLTP0000001012071.959962.0887
ENSG00000204842homo_sapiensENSP0000050092557.575852.1212notechis_scutatusENSNSUP0000001716379.450471.9235
ENSG00000204842homo_sapiensENSP0000050092563.376656.6234pseudonaja_textilisENSPTXP0000002323972.763465.0099
ENSG00000204842homo_sapiensENSP0000050092585.627781.039anas_platyrhynchos_platyrhynchosENSAPLP0000000845693.655388.6364
ENSG00000204842homo_sapiensENSP0000050092584.069379.1342gallus_gallusENSGALP0001003887591.776986.3894
ENSG00000204842homo_sapiensENSP0000050092584.675379.0476meleagris_gallopavoENSMGAP0000002540186.167480.4405
ENSG00000204842homo_sapiensENSP0000050092579.826875.1515serinus_canariaENSSCAP0000001166493.509188.0325
ENSG00000204842homo_sapiensENSP0000050092579.567174.8918parus_majorENSPMJP0000000528592.547887.1098
ENSG00000204842homo_sapiensENSP0000050092582.251175.7576anolis_carolinensisENSACAP0000002792084.594877.9163
ENSG00000204842homo_sapiensENSP0000050092565.281455.671neolamprologus_brichardiENSNBRP0000002063471.266560.775
ENSG00000204842homo_sapiensENSP0000050092546.406942.3377naja_najaENSNNAP0000002855386.035378.4912
ENSG00000204842homo_sapiensENSP0000050092585.800979.9134podarcis_muralisENSPMRP0000001190183.207477.4979
ENSG00000204842homo_sapiensENSP0000050092578.181873.5931geospiza_fortisENSGFOP0000000273594.258988.7265
ENSG00000204842homo_sapiensENSP0000050092580.432975.3247taeniopygia_guttataENSTGUP0000003104990.989285.2106
ENSG00000204842homo_sapiensENSP0000050092568.051958.7013erpetoichthys_calabaricusENSECRP0000003158175.795665.3809
ENSG00000204842homo_sapiensENSP0000050092564.415653.8528kryptolebias_marmoratusENSKMAP0000000122370.924759.2946
ENSG00000204842homo_sapiensENSP0000050092583.549878.0952salvator_merianaeENSSMRP0000001166089.600783.7512
ENSG00000204842homo_sapiensENSP0000050092534.285728.5714oryzias_javanicusENSOJAP0000003173464.600353.8336
ENSG00000204842homo_sapiensENSP0000050092521.125517.9221oryzias_javanicusENSOJAP0000003175176.971665.2997
ENSG00000204842homo_sapiensENSP0000050092562.770653.2468amphilophus_citrinellusENSACIP0000000635971.288160.472
ENSG00000204842homo_sapiensENSP0000050092564.415653.6797dicentrarchus_labraxENSDLAP0000504619170.722458.9354
ENSG00000204842homo_sapiensENSP0000050092564.069353.1602amphiprion_perculaENSAPEP0000002852469.614357.7611
ENSG00000204842homo_sapiensENSP0000050092564.502253.0736oryzias_sinensisENSOSIP0000004678568.223456.1355
ENSG00000204842homo_sapiensENSP0000050092525.194824.6753pelodiscus_sinensisENSPSIP0000001810495.09893.1373
ENSG00000204842homo_sapiensENSP0000050092586.406981.1255pelodiscus_sinensisENSPSIP0000000238593.010387.3253
ENSG00000204842homo_sapiensENSP0000050092520.519518.2684pelodiscus_sinensisENSPSIP0000001533486.181876.7273
ENSG00000204842homo_sapiensENSP0000050092584.588779.3074gopherus_evgoodeiENSGEVP0000502927789.63384.0367
ENSG00000204842homo_sapiensENSP0000050092586.233881.3853chelonoidis_abingdoniiENSCABP0000002074093.171287.9326
ENSG00000204842homo_sapiensENSP0000050092564.32953.9394seriola_dumeriliENSSDUP0000000153869.439358.2243
ENSG00000204842homo_sapiensENSP0000050092569.69758.8745cottoperca_gobioENSCGOP0000000038271.238960.177
ENSG00000204842homo_sapiensENSP0000050092579.134274.8918struthio_camelus_australisENSSCUP0000000237692.791987.8173
ENSG00000204842homo_sapiensENSP0000050092587.359382.684anser_brachyrhynchusENSABRP0000002123092.73987.7757
ENSG00000204842homo_sapiensENSP0000050092566.060656.5368gasterosteus_aculeatusENSGACP0000000833071.57661.257
ENSG00000204842homo_sapiensENSP0000050092562.770651.8615cynoglossus_semilaevisENSCSEP0000001409566.574855.0046
ENSG00000204842homo_sapiensENSP0000050092562.857152.4675cynoglossus_semilaevisENSCSEP0000002868968.815257.4408
ENSG00000204842homo_sapiensENSP0000050092561.471951.342poecilia_formosaENSPFOP0000000624671.500559.718
ENSG00000204842homo_sapiensENSP0000050092538.441632.1212myripristis_murdjanENSMMDP0000503859378.445265.5477
ENSG00000204842homo_sapiensENSP0000050092565.541155.8442sander_luciopercaENSSLUP0000005193170.484260.0559
ENSG00000204842homo_sapiensENSP0000050092586.060681.2987strigops_habroptilaENSSHBP0000501059891.192786.1468
ENSG00000204842homo_sapiensENSP0000050092564.32953.6797amphiprion_ocellarisENSAOCP0000002730070.560358.8794
ENSG00000204842homo_sapiensENSP0000050092586.233881.8182terrapene_carolina_triunguisENSTMTP0000002088791.966887.2576
ENSG00000204842homo_sapiensENSP0000050092560.086649.0043hucho_huchoENSHHUP0000000786469.123556.3745
ENSG00000204842homo_sapiensENSP0000050092566.926456.2771hucho_huchoENSHHUP0000003488671.640460.241
ENSG00000204842homo_sapiensENSP0000050092566.147255.671betta_splendensENSBSLP0000000569970.349959.2081
ENSG00000204842homo_sapiensENSP0000050092565.36855.0649pygocentrus_nattereriENSPNAP0000002569072.387360.9779
ENSG00000204842homo_sapiensENSP0000050092566.580155.9307anabas_testudineusENSATEP0000002696971.40259.9814
ENSG00000204842homo_sapiensENSP0000050092524.588715.5844saccharomyces_cerevisiaeYGR178C39.335224.9307
ENSG00000204842homo_sapiensENSP0000050092564.502254.8918seriola_lalandi_dorsalisENSSLDP0000002558772.050361.3153
ENSG00000204842homo_sapiensENSP0000050092533.246828.4848labrus_bergyltaENSLBEP0000002283764.429555.2013
ENSG00000204842homo_sapiensENSP0000050092529.264122.7706labrus_bergyltaENSLBEP0000002289573.638357.2985
ENSG00000204842homo_sapiensENSP0000050092531.601727.0996pundamilia_nyerereiENSPNYP0000002254268.224358.5047
ENSG00000204842homo_sapiensENSP0000050092532.813927.2727pundamilia_nyerereiENSPNYP0000002245877.189464.1548
ENSG00000204842homo_sapiensENSP0000050092564.415654.3723mastacembelus_armatusENSMAMP0000002848771.060259.9809
ENSG00000204842homo_sapiensENSP0000050092565.108254.7186stegastes_partitusENSSPAP0000000055769.565258.4644
ENSG00000204842homo_sapiensENSP0000050092545.97436.8831oncorhynchus_tshawytschaENSOTSP0000503198469.68555.9055
ENSG00000204842homo_sapiensENSP0000050092555.497847.013oncorhynchus_tshawytschaENSOTSP0000508487871.301460.4004
ENSG00000204842homo_sapiensENSP0000050092564.242453.4199acanthochromis_polyacanthusENSAPOP0000002903969.802458.0433
ENSG00000204842homo_sapiensENSP0000050092587.532582.5974aquila_chrysaetos_chrysaetosENSACCP0002000702690.187385.1026
ENSG00000204842homo_sapiensENSP0000050092567.532555.0649nothobranchius_furzeriENSNFUP0001502586366.83854.4987
ENSG00000204842homo_sapiensENSP0000050092566.839855.0649cyprinodon_variegatusENSCVAP0000003100469.175656.9892
ENSG00000204842homo_sapiensENSP0000050092562.424252.2078denticeps_clupeoidesENSDCDP0000000762869.661858.2609
ENSG00000204842homo_sapiensENSP0000050092566.493555.9307larimichthys_croceaENSLCRP0000500722068.085157.2695
ENSG00000204842homo_sapiensENSP0000050092565.627754.8918takifugu_rubripesENSTRUP0000004303867.198656.2057
ENSG00000204842homo_sapiensENSP0000050092578.35573.8528ficedula_albicollisENSFALP0000000940194.270888.8542
ENSG00000204842homo_sapiensENSP0000050092562.077951.0823hippocampus_comesENSHCOP0000001973666.450454.6803
ENSG00000204842homo_sapiensENSP0000050092565.281454.8052cyprinus_carpio_carpioENSCCRP0000007170868.35957.3889
ENSG00000204842homo_sapiensENSP0000050092565.454556.0173cyprinus_carpio_carpioENSCCRP0000013799867.557.7679
ENSG00000204842homo_sapiensENSP0000050092579.653774.8918coturnix_japonicaENSCJPP0000500011293.781988.1753
ENSG00000204842homo_sapiensENSP0000050092563.982752.5541poecilia_latipinnaENSPLAP0000001202371.539258.7609
ENSG00000204842homo_sapiensENSP0000050092565.36856.3636sinocyclocheilus_grahamiENSSGRP0000008681173.658563.5122
ENSG00000204842homo_sapiensENSP0000050092565.108255.2381sinocyclocheilus_grahamiENSSGRP0000010754369.117658.6397
ENSG00000204842homo_sapiensENSP0000050092564.761953.9394maylandia_zebraENSMZEP0000501126871.035159.1643
ENSG00000204842homo_sapiensENSP000005009256.839835.45455tetraodon_nigroviridisENSTNIP0000000868156.028444.6809
ENSG00000204842homo_sapiensENSP000005009257.965376.66667tetraodon_nigroviridisENSTNIP0000000490569.172957.8947
ENSG00000204842homo_sapiensENSP0000050092566.839856.8831paramormyrops_kingsleyaeENSPKIP0000000714173.664162.6908
ENSG00000204842homo_sapiensENSP0000050092566.666756.4502scleropages_formosusENSSFOP0001507363574.684863.2396
ENSG00000204842homo_sapiensENSP0000050092583.116976.1039leptobrachium_leishanenseENSLLEP0000001697584.880677.7188
ENSG00000204842homo_sapiensENSP0000050092563.636453.1602scophthalmus_maximusENSSMAP0000004385168.308557.0632
ENSG00000204842homo_sapiensENSP0000050092562.857151.9481oryzias_melastigmaENSOMEP0000001838169.407357.3614

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0002091involved_in negative regulation of receptor internalization1IMPHomo_sapiens(9606)Process
GO:0003723enables RNA binding2HDA,NASHomo_sapiens(9606)Function
GO:0003729enables mRNA binding1IBAHomo_sapiens(9606)Function
GO:0005154enables epidermal growth factor receptor binding1IPIHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005794located_in Golgi apparatus1IDAHomo_sapiens(9606)Component
GO:0005802located_in trans-Golgi network1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0005844part_of polysome1IDAHomo_sapiens(9606)Component
GO:0006417involved_in regulation of translation1NASHomo_sapiens(9606)Process
GO:0010494is_active_in cytoplasmic stress granule2IBA,IDAHomo_sapiens(9606)Component
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0016070involved_in RNA metabolic process1NASHomo_sapiens(9606)Process
GO:0033962involved_in P-body assembly1IMPHomo_sapiens(9606)Process
GO:0034063involved_in stress granule assembly2IBA,IMPHomo_sapiens(9606)Process
GO:0048471located_in perinuclear region of cytoplasm1IDAHomo_sapiens(9606)Component
GO:0050658involved_in RNA transport1NASHomo_sapiens(9606)Process
GO:1990904part_of ribonucleoprotein complex1IDAHomo_sapiens(9606)Component

Expression