Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations P-body
BulkPerturb-seq DataSet_01_224 DataSet_01_422

Description

Ensembl ID ENSG00000198791 Gene ID 29883 Accession 14101
Symbol CNOT7 Alias CAF1;CAF-1;Caf1a;hCAF-1 Full Name CCR4-NOT transcription complex subunit 7
Status Confidence Length 21913 bases Strand Minus strand
Position 8 : 17224966 - 17246878 RNA binding domain CAF1
Summary The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Apr 2016]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000429093 CAF1 PF04857 9.2e-22 1
ENSP00000429093 CAF1 PF04857 9.2e-22 2
ENSP00000355279 CAF1 PF04857 1.8e-21 1
ENSP00000355279 CAF1 PF04857 1.8e-21 2
ENSP00000428147 CAF1 PF04857 3.7e-18 1
ENSP00000428147 CAF1 PF04857 3.7e-18 2
ENSP00000430160 CAF1 PF04857 6.7e-12 1
ENSP00000430263 CAF1 PF04857 5.3e-05 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
26518565 Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach. Yuwei Bai 2015-12-01 Protein & cell
29185492 Interaction profiling of RNA-binding ubiquitin ligases reveals a link between posttranscriptional regulation and the ubiquitin system. Andrea Hildebrandt 2017-11-29 Scientific reports
30349044 Engineering protein-protein devices for multilayered regulation of mRNA translation using orthogonal proteases in mammalian cells. Federica Cella 2018-10-22 Nature communications
28525643 Synthetic mRNA devices that detect endogenous proteins and distinguish mammalian cells. Shunsuke Kawasaki 2017-07-07 Nucleic acids research

Transcripts

Name Transcript ID bp Protein Translation ID
CNOT7-201 ENST00000361272 6890 285aa ENSP00000355279
CNOT7-203 ENST00000518541 426 91aa ENSP00000430263
CNOT7-211 ENST00000523917 1885 244aa ENSP00000429093
CNOT7-206 ENST00000519954 1209 51aa ENSP00000429632
CNOT7-205 ENST00000519918 680 208aa ENSP00000428147
CNOT7-209 ENST00000522062 444 No protein -
CNOT7-212 ENST00000524358 700 147aa ENSP00000430160
CNOT7-207 ENST00000519998 1909 No protein -
CNOT7-202 ENST00000518021 768 62aa ENSP00000428783
CNOT7-208 ENST00000520178 568 40aa ENSP00000429079
CNOT7-204 ENST00000518885 477 No protein -
CNOT7-210 ENST00000523649 699 No protein -
CNOT7-213 ENST00000628418 432 51aa ENSP00000487113

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000198791homo_sapiensENSP0000028589686.301474.3151homo_sapiensENSP0000035527988.421176.1404

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000198791homo_sapiensENSP00000355279100100nomascus_leucogenysENSNLEP00000003079100100
ENSG00000198791homo_sapiensENSP00000355279100100pan_paniscusENSPPAP00000028144100100
ENSG00000198791homo_sapiensENSP00000355279100100pongo_abeliiENSPPYP00000020597100100
ENSG00000198791homo_sapiensENSP00000355279100100pan_troglodytesENSPTRP00000078280100100
ENSG00000198791homo_sapiensENSP00000355279100100gorilla_gorillaENSGGOP00000018858100100
ENSG00000198791homo_sapiensENSP0000035527910099.2982ornithorhynchus_anatinusENSOANP0000001647010099.2982
ENSG00000198791homo_sapiensENSP0000035527999.298298.5965sarcophilus_harrisiiENSSHAP0000004512595.286294.6128
ENSG00000198791homo_sapiensENSP0000035527991.578986.6667sarcophilus_harrisiiENSSHAP0000000112494.565289.4928
ENSG00000198791homo_sapiensENSP0000035527992.982592.2807choloepus_hoffmanniENSCHOP0000000060092.982592.2807
ENSG00000198791homo_sapiensENSP00000355279100100dasypus_novemcinctusENSDNOP00000024278100100
ENSG00000198791homo_sapiensENSP0000035527984.210584.2105erinaceus_europaeusENSEEUP0000001000999.173699.1736
ENSG00000198791homo_sapiensENSP0000035527984.561484.2105echinops_telfairiENSETEP0000000121699.586899.1736
ENSG00000198791homo_sapiensENSP00000355279100100callithrix_jacchusENSCJAP00000021686100100
ENSG00000198791homo_sapiensENSP00000355279100100cercocebus_atysENSCATP00000028359100100
ENSG00000198791homo_sapiensENSP00000355279100100macaca_fascicularisENSMFAP00000037373100100
ENSG00000198791homo_sapiensENSP0000035527978.245671.9298macaca_mulattaENSMMUP0000005567855.61151.1222
ENSG00000198791homo_sapiensENSP00000355279100100macaca_nemestrinaENSMNEP00000014665100100
ENSG00000198791homo_sapiensENSP00000355279100100papio_anubisENSPANP00000008270100100
ENSG00000198791homo_sapiensENSP0000035527998.947498.9474mandrillus_leucophaeusENSMLEP00000018329100100
ENSG00000198791homo_sapiensENSP00000355279100100tursiops_truncatusENSTTRP00000011922100100
ENSG00000198791homo_sapiensENSP00000355279100100vulpes_vulpesENSVVUP00000010055100100
ENSG00000198791homo_sapiensENSP0000035527910099.6491mus_spretusMGP_SPRETEiJ_P008771110099.6491
ENSG00000198791homo_sapiensENSP00000355279100100equus_asinusENSEASP00005025114100100
ENSG00000198791homo_sapiensENSP0000035527910099.6491capra_hircusENSCHIP0000000882310099.6491
ENSG00000198791homo_sapiensENSP00000355279100100loxodonta_africanaENSLAFP00000000195100100
ENSG00000198791homo_sapiensENSP00000355279100100panthera_leoENSPLOP00000029646100100
ENSG00000198791homo_sapiensENSP00000355279100100ailuropoda_melanoleucaENSAMEP00000014507100100
ENSG00000198791homo_sapiensENSP0000035527910099.6491bos_indicus_hybridENSBIXP0000500728710099.6491
ENSG00000198791homo_sapiensENSP0000035527981.052681.0526oryctolagus_cuniculusENSOCUP00000019787100100
ENSG00000198791homo_sapiensENSP00000355279100100oryctolagus_cuniculusENSOCUP00000012542100100
ENSG00000198791homo_sapiensENSP0000035527985.964985.614equus_caballusENSECAP0000000407288.768188.4058
ENSG00000198791homo_sapiensENSP00000355279100100canis_lupus_familiarisENSCAFP00845020574100100
ENSG00000198791homo_sapiensENSP00000355279100100panthera_pardusENSPPRP00000004873100100
ENSG00000198791homo_sapiensENSP0000035527981.052681.0526marmota_marmota_marmotaENSMMMP0000002677198.297998.2979
ENSG00000198791homo_sapiensENSP00000355279100100marmota_marmota_marmotaENSMMMP00000010338100100
ENSG00000198791homo_sapiensENSP0000035527910099.6491balaenoptera_musculusENSBMSP0001003064710099.6491
ENSG00000198791homo_sapiensENSP00000355279100100cavia_porcellusENSCPOP00000023165100100
ENSG00000198791homo_sapiensENSP00000355279100100felis_catusENSFCAP00000000549100100
ENSG00000198791homo_sapiensENSP00000355279100100ursus_americanusENSUAMP00000014659100100
ENSG00000198791homo_sapiensENSP0000035527947.719344.2105monodelphis_domesticaENSMODP0000004528582.424276.3636
ENSG00000198791homo_sapiensENSP0000035527978.596574.0351monodelphis_domesticaENSMODP0000004333990.322685.0806
ENSG00000198791homo_sapiensENSP0000035527910099.2982monodelphis_domesticaENSMODP0000002378910099.2982
ENSG00000198791homo_sapiensENSP0000035527910099.6491bison_bison_bisonENSBBBP0000000503510099.6491
ENSG00000198791homo_sapiensENSP00000355279100100monodon_monocerosENSMMNP00015015175100100
ENSG00000198791homo_sapiensENSP00000355279100100sus_scrofaENSSSCP00000039703100100
ENSG00000198791homo_sapiensENSP0000035527984.912384.5614microcebus_murinusENSMICP0000002723299.588599.177
ENSG00000198791homo_sapiensENSP00000355279100100microcebus_murinusENSMICP00000033799100100
ENSG00000198791homo_sapiensENSP00000355279100100octodon_degusENSODEP00000008688100100
ENSG00000198791homo_sapiensENSP0000035527978.596576.1404octodon_degusENSODEP0000000022095.319192.3404
ENSG00000198791homo_sapiensENSP0000035527968.771967.0175octodon_degusENSODEP0000001658593.779991.3876
ENSG00000198791homo_sapiensENSP0000035527910099.6491jaculus_jaculusENSJJAP0000001138210099.6491
ENSG00000198791homo_sapiensENSP0000035527988.070287.3684jaculus_jaculusENSJJAP0000002363189.642988.9286
ENSG00000198791homo_sapiensENSP0000035527910099.6491ovis_aries_rambouilletENSOARP0002002958810099.6491
ENSG00000198791homo_sapiensENSP00000355279100100ursus_maritimusENSUMAP00000028376100100
ENSG00000198791homo_sapiensENSP0000035527958.596558.5965ochotona_princepsENSOPRP00000000506100100
ENSG00000198791homo_sapiensENSP00000355279100100delphinapterus_leucasENSDLEP00000009628100100
ENSG00000198791homo_sapiensENSP0000035527978.596578.2456physeter_catodonENSPCTP0000502349696.137395.7082
ENSG00000198791homo_sapiensENSP00000355279100100physeter_catodonENSPCTP00005006733100100
ENSG00000198791homo_sapiensENSP0000035527997.543997.193mus_caroliMGP_CAROLIEiJ_P008423297.543997.193
ENSG00000198791homo_sapiensENSP0000035527910099.6491mus_musculusENSMUSP0000011730410099.6491
ENSG00000198791homo_sapiensENSP00000355279100100dipodomys_ordiiENSDORP00000025955100100
ENSG00000198791homo_sapiensENSP00000355279100100mustela_putorius_furoENSMPUP00000017861100100
ENSG00000198791homo_sapiensENSP0000035527985.964983.8596aotus_nancymaaeENSANAP0000001991194.961292.6357
ENSG00000198791homo_sapiensENSP00000355279100100aotus_nancymaaeENSANAP00000006531100100
ENSG00000198791homo_sapiensENSP00000355279100100saimiri_boliviensis_boliviensisENSSBOP00000025061100100
ENSG00000198791homo_sapiensENSP00000355279100100vicugna_pacosENSVPAP00000011115100100
ENSG00000198791homo_sapiensENSP00000355279100100chlorocebus_sabaeusENSCSAP00000012834100100
ENSG00000198791homo_sapiensENSP00000355279100100tupaia_belangeriENSTBEP00000005242100100
ENSG00000198791homo_sapiensENSP00000355279100100mesocricetus_auratusENSMAUP00000019777100100
ENSG00000198791homo_sapiensENSP00000355279100100phocoena_sinusENSPSNP00000022227100100
ENSG00000198791homo_sapiensENSP00000355279100100camelus_dromedariusENSCDRP00005028866100100
ENSG00000198791homo_sapiensENSP00000355279100100carlito_syrichtaENSTSYP00000034506100100
ENSG00000198791homo_sapiensENSP0000035527910099.6491panthera_tigris_altaicaENSPTIP0000001201310099.6491
ENSG00000198791homo_sapiensENSP0000035527910099.6491rattus_norvegicusENSRNOP0000001688210099.6491
ENSG00000198791homo_sapiensENSP00000355279100100prolemur_simusENSPSMP00000009175100100
ENSG00000198791homo_sapiensENSP00000355279100100microtus_ochrogasterENSMOCP00000016962100100
ENSG00000198791homo_sapiensENSP0000035527984.561484.5614sorex_araneusENSSARP0000000293184.561484.5614
ENSG00000198791homo_sapiensENSP0000035527936.491236.1404peromyscus_maniculatus_bairdiiENSPEMP0000003455610099.0385
ENSG00000198791homo_sapiensENSP0000035527995.438695.4386peromyscus_maniculatus_bairdiiENSPEMP0000002365096.453996.4539
ENSG00000198791homo_sapiensENSP0000035527910099.6491bos_mutusENSBMUP0000003178110099.6491
ENSG00000198791homo_sapiensENSP0000035527910099.6491mus_spicilegusENSMSIP0000001353510099.6491
ENSG00000198791homo_sapiensENSP00000355279100100cricetulus_griseus_chok1gshdENSCGRP00001009005100100
ENSG00000198791homo_sapiensENSP0000035527985.263285.2632pteropus_vampyrusENSPVAP00000011050100100
ENSG00000198791homo_sapiensENSP00000355279100100myotis_lucifugusENSMLUP00000001480100100
ENSG00000198791homo_sapiensENSP0000035527910099.2982vombatus_ursinusENSVURP0001000721910099.2982
ENSG00000198791homo_sapiensENSP00000355279100100rhinolophus_ferrumequinumENSRFEP00010006547100100
ENSG00000198791homo_sapiensENSP00000355279100100neovison_visonENSNVIP00000009256100100
ENSG00000198791homo_sapiensENSP0000035527910099.6491bos_taurusENSBTAP0000002400910099.6491
ENSG00000198791homo_sapiensENSP0000035527988.070283.8596heterocephalus_glaber_femaleENSHGLP0000002287290.94286.5942
ENSG00000198791homo_sapiensENSP0000035527910099.6491heterocephalus_glaber_femaleENSHGLP0000004141898.615998.2699
ENSG00000198791homo_sapiensENSP00000355279100100rhinopithecus_bietiENSRBIP00000009804100100
ENSG00000198791homo_sapiensENSP00000355279100100canis_lupus_dingoENSCAFP00020000395100100
ENSG00000198791homo_sapiensENSP0000035527998.947498.5965sciurus_vulgarisENSSVLP0000501367098.947498.5965
ENSG00000198791homo_sapiensENSP0000035527999.649199.2982sciurus_vulgarisENSSVLP0000501757399.649199.2982
ENSG00000198791homo_sapiensENSP00000355279100100sciurus_vulgarisENSSVLP00005018069100100
ENSG00000198791homo_sapiensENSP0000035527924.561424.2105phascolarctos_cinereusENSPCIP0000000871689.743688.4615
ENSG00000198791homo_sapiensENSP0000035527910099.2982phascolarctos_cinereusENSPCIP0000000332610099.2982
ENSG00000198791homo_sapiensENSP0000035527959.298258.5965procavia_capensisENSPCAP0000001486668.979668.1633
ENSG00000198791homo_sapiensENSP00000355279100100nannospalax_galiliENSNGAP00000013928100100
ENSG00000198791homo_sapiensENSP0000035527989.824688.0702bos_grunniensENSBGRP0000001575085.618783.9465
ENSG00000198791homo_sapiensENSP00000355279100100chinchilla_lanigeraENSCLAP00000000993100100
ENSG00000198791homo_sapiensENSP0000035527910099.6491cervus_hanglu_yarkandensisENSCHYP0000002727910099.6491
ENSG00000198791homo_sapiensENSP00000355279100100catagonus_wagneriENSCWAP00000022938100100
ENSG00000198791homo_sapiensENSP00000355279100100ictidomys_tridecemlineatusENSSTOP00000026570100100
ENSG00000198791homo_sapiensENSP0000035527929.824628.4211ictidomys_tridecemlineatusENSSTOP0000002711493.406689.011
ENSG00000198791homo_sapiensENSP00000355279100100otolemur_garnettiiENSOGAP00000005652100100
ENSG00000198791homo_sapiensENSP00000355279100100cebus_imitatorENSCCAP00000028246100100
ENSG00000198791homo_sapiensENSP0000035527967.368464.5614cebus_imitatorENSCCAP0000001304093.203989.3204
ENSG00000198791homo_sapiensENSP00000355279100100urocitellus_parryiiENSUPAP00010011192100100
ENSG00000198791homo_sapiensENSP0000035527910099.6491moschus_moschiferusENSMMSP0000000775610099.6491
ENSG00000198791homo_sapiensENSP00000355279100100rhinopithecus_roxellanaENSRROP00000021465100100
ENSG00000198791homo_sapiensENSP0000035527910099.6491mus_pahariMGP_PahariEiJ_P004712910099.6491
ENSG00000198791homo_sapiensENSP0000035527983.157982.4561propithecus_coquereliENSPCOP0000000247796.734795.9184
ENSG00000198791homo_sapiensENSP0000035527998.947498.9474propithecus_coquereliENSPCOP0000002855993.069393.0693
ENSG00000198791homo_sapiensENSP0000035527984.912384.9123propithecus_coquereliENSPCOP0000002976997.188897.1888
ENSG00000198791homo_sapiensENSP0000035527965.964946.3158caenorhabditis_elegansY56A3A.20.160.645242.5806
ENSG00000198791homo_sapiensENSP0000035527982.80768.4211drosophila_melanogasterFBpp031108965.37454.0166
ENSG00000198791homo_sapiensENSP0000035527982.456170.8772ciona_intestinalisENSCINP0000000609684.532472.6619
ENSG00000198791homo_sapiensENSP0000035527950.175439.2982eptatretus_burgeriENSEBUP0000002428365.596351.3761
ENSG00000198791homo_sapiensENSP0000035527998.947497.8947callorhinchus_miliiENSCMIP0000003200298.601497.5524
ENSG00000198791homo_sapiensENSP0000035527999.649198.9474latimeria_chalumnaeENSLACP0000001074499.300798.6014
ENSG00000198791homo_sapiensENSP0000035527998.947496.1404lepisosteus_oculatusENSLOCP0000001718398.601495.8042
ENSG00000198791homo_sapiensENSP0000035527998.245696.1404clupea_harengusENSCHAP0000001069697.902195.8042
ENSG00000198791homo_sapiensENSP0000035527998.947495.7895danio_rerioENSDARP0000008738598.601495.4545
ENSG00000198791homo_sapiensENSP0000035527998.596596.1404carassius_auratusENSCARP0000002852998.251795.8042
ENSG00000198791homo_sapiensENSP0000035527998.245695.4386carassius_auratusENSCARP0000008325897.902195.1049
ENSG00000198791homo_sapiensENSP0000035527998.596595.7895carassius_auratusENSCARP0000009238398.251795.4545
ENSG00000198791homo_sapiensENSP0000035527998.947496.4912astyanax_mexicanusENSAMXP0000000829098.601496.1538
ENSG00000198791homo_sapiensENSP0000035527998.596594.7368ictalurus_punctatusENSIPUP0000003179798.251794.4056
ENSG00000198791homo_sapiensENSP0000035527998.947494.386esox_luciusENSELUP0000003209698.601494.0559
ENSG00000198791homo_sapiensENSP0000035527998.947496.4912electrophorus_electricusENSEEEP0000004256898.601496.1538
ENSG00000198791homo_sapiensENSP0000035527998.596596.1404oncorhynchus_kisutchENSOKIP0000501615298.251795.8042
ENSG00000198791homo_sapiensENSP0000035527998.596596.1404oncorhynchus_mykissENSOMYP0000008770798.251795.8042
ENSG00000198791homo_sapiensENSP0000035527991.228185.9649salmo_salarENSSSAP0000010459366.666762.8205
ENSG00000198791homo_sapiensENSP0000035527998.596596.1404salmo_truttaENSSTUP0000008945698.251795.8042
ENSG00000198791homo_sapiensENSP0000035527998.596593.6842gadus_morhuaENSGMOP0000000523892.131187.541
ENSG00000198791homo_sapiensENSP0000035527989.824684.5614fundulus_heteroclitusENSFHEP0000001409284.210579.2763
ENSG00000198791homo_sapiensENSP0000035527999.298295.4386poecilia_reticulataENSPREP0000003265798.95195.1049
ENSG00000198791homo_sapiensENSP0000035527999.298295.7895xiphophorus_maculatusENSXMAP0000003947298.95195.4545
ENSG00000198791homo_sapiensENSP0000035527997.894793.6842oryzias_latipesENSORLP0000004226197.552493.3566
ENSG00000198791homo_sapiensENSP0000035527997.894793.6842cyclopterus_lumpusENSCLMP0000500155297.552493.3566
ENSG00000198791homo_sapiensENSP0000035527998.947494.7368oreochromis_niloticusENSONIP0000005238298.601494.4056
ENSG00000198791homo_sapiensENSP0000035527998.947494.7368haplochromis_burtoniENSHBUP0000000076498.601494.4056
ENSG00000198791homo_sapiensENSP0000035527998.947494.7368astatotilapia_callipteraENSACLP0000003473290.967787.0968
ENSG00000198791homo_sapiensENSP0000035527986.666781.7544sparus_aurataENSSAUP0001003627185.763980.9028
ENSG00000198791homo_sapiensENSP0000035527998.947495.0877lates_calcariferENSLCAP0001000226698.601494.7552
ENSG00000198791homo_sapiensENSP0000035527998.947496.8421xenopus_tropicalisENSXETP0000000156493.687791.6944
ENSG00000198791homo_sapiensENSP00000355279100100chrysemys_picta_belliiENSCPBP00000026597100100
ENSG00000198791homo_sapiensENSP0000035527999.298299.2982sphenodon_punctatusENSSPUP0000002231199.298299.2982
ENSG00000198791homo_sapiensENSP00000355279100100crocodylus_porosusENSCPRP00005015359100100
ENSG00000198791homo_sapiensENSP0000035527910099.6491laticauda_laticaudataENSLLTP0000001633410099.6491
ENSG00000198791homo_sapiensENSP0000035527910099.6491notechis_scutatusENSNSUP0000001226610099.6491
ENSG00000198791homo_sapiensENSP0000035527910099.6491pseudonaja_textilisENSPTXP0000000542010099.6491
ENSG00000198791homo_sapiensENSP00000355279100100anas_platyrhynchos_platyrhynchosENSAPLP00000011100100100
ENSG00000198791homo_sapiensENSP00000355279100100gallus_gallusENSGALP00010022291100100
ENSG00000198791homo_sapiensENSP0000035527975.789575.0877meleagris_gallopavoENSMGAP0000001214094.323193.4498
ENSG00000198791homo_sapiensENSP00000355279100100serinus_canariaENSSCAP00000012715100100
ENSG00000198791homo_sapiensENSP0000035527987.719386.6667parus_majorENSPMJP0000000713487.412686.3636
ENSG00000198791homo_sapiensENSP0000035527910099.6491anolis_carolinensisENSACAP0000000612410099.6491
ENSG00000198791homo_sapiensENSP0000035527998.947494.7368neolamprologus_brichardiENSNBRP0000002684098.601494.4056
ENSG00000198791homo_sapiensENSP0000035527910099.2982naja_najaENSNNAP0000001031489.905489.2744
ENSG00000198791homo_sapiensENSP0000035527910099.2982podarcis_muralisENSPMRP0000001931610099.2982
ENSG00000198791homo_sapiensENSP00000355279100100geospiza_fortisENSGFOP00000009824100100
ENSG00000198791homo_sapiensENSP00000355279100100taeniopygia_guttataENSTGUP00000007471100100
ENSG00000198791homo_sapiensENSP0000035527999.298296.8421erpetoichthys_calabaricusENSECRP0000000189198.95196.5035
ENSG00000198791homo_sapiensENSP0000035527999.298295.7895kryptolebias_marmoratusENSKMAP0000002014998.95195.4545
ENSG00000198791homo_sapiensENSP0000035527910099.6491salvator_merianaeENSSMRP0000001218410099.6491
ENSG00000198791homo_sapiensENSP0000035527998.245694.0351oryzias_javanicusENSOJAP0000001726697.902193.7063
ENSG00000198791homo_sapiensENSP0000035527998.947494.7368amphilophus_citrinellusENSACIP0000002788498.601494.4056
ENSG00000198791homo_sapiensENSP0000035527998.947494.7368dicentrarchus_labraxENSDLAP0000507294396.907292.7835
ENSG00000198791homo_sapiensENSP0000035527998.947494.7368amphiprion_perculaENSAPEP0000001303398.601494.4056
ENSG00000198791homo_sapiensENSP00000355279100100pelodiscus_sinensisENSPSIP00000014007100100
ENSG00000198791homo_sapiensENSP0000035527976.140474.0351gopherus_evgoodeiENSGEVP0000500121088.571486.1225
ENSG00000198791homo_sapiensENSP00000355279100100chelonoidis_abingdoniiENSCABP00000018815100100
ENSG00000198791homo_sapiensENSP0000035527998.947495.0877seriola_dumeriliENSSDUP0000001695598.601494.7552
ENSG00000198791homo_sapiensENSP0000035527998.245694.0351cottoperca_gobioENSCGOP0000001125897.902193.7063
ENSG00000198791homo_sapiensENSP00000355279100100struthio_camelus_australisENSSCUP00000000837100100
ENSG00000198791homo_sapiensENSP00000355279100100anser_brachyrhynchusENSABRP00000023733100100
ENSG00000198791homo_sapiensENSP0000035527998.596592.2807gasterosteus_aculeatusENSGACP0000002459497.231891.0035
ENSG00000198791homo_sapiensENSP0000035527998.947495.0877cynoglossus_semilaevisENSCSEP0000002867198.601494.7552
ENSG00000198791homo_sapiensENSP0000035527999.298295.4386poecilia_formosaENSPFOP0000000154298.95195.1049
ENSG00000198791homo_sapiensENSP0000035527998.947496.1404myripristis_murdjanENSMMDP0000503923298.601495.8042
ENSG00000198791homo_sapiensENSP0000035527998.596594.0351sander_luciopercaENSSLUP0000006012798.251793.7063
ENSG00000198791homo_sapiensENSP00000355279100100strigops_habroptilaENSSHBP00005012590100100
ENSG00000198791homo_sapiensENSP0000035527998.947495.0877amphiprion_ocellarisENSAOCP0000001372198.601494.7552
ENSG00000198791homo_sapiensENSP00000355279100100terrapene_carolina_triunguisENSTMTP00000010245100100
ENSG00000198791homo_sapiensENSP0000035527998.245696.4912hucho_huchoENSHHUP0000006380597.902196.1538
ENSG00000198791homo_sapiensENSP0000035527998.947495.0877betta_splendensENSBSLP0000001674690.675287.1383
ENSG00000198791homo_sapiensENSP0000035527998.947496.8421pygocentrus_nattereriENSPNAP0000003269398.601496.5035
ENSG00000198791homo_sapiensENSP0000035527998.596594.7368anabas_testudineusENSATEP0000002766498.251794.4056
ENSG00000198791homo_sapiensENSP0000035527983.508870.5263ciona_savignyiENSCSAVP000000034878571.7857
ENSG00000198791homo_sapiensENSP0000035527958.947438.5965saccharomyces_cerevisiaeYNR052C38.799125.4042
ENSG00000198791homo_sapiensENSP0000035527998.947495.0877seriola_lalandi_dorsalisENSSLDP0000003087798.601494.7552
ENSG00000198791homo_sapiensENSP0000035527998.596594.386labrus_bergyltaENSLBEP0000002124998.251794.0559
ENSG00000198791homo_sapiensENSP0000035527998.947494.7368pundamilia_nyerereiENSPNYP0000000012498.601494.4056
ENSG00000198791homo_sapiensENSP0000035527998.947495.0877mastacembelus_armatusENSMAMP0000002385698.601494.7552
ENSG00000198791homo_sapiensENSP0000035527985.964982.1053stegastes_partitusENSSPAP0000002513398.393693.9759
ENSG00000198791homo_sapiensENSP0000035527985.263281.4035stegastes_partitusENSSPAP0000001592197.983993.5484
ENSG00000198791homo_sapiensENSP0000035527998.596596.1404oncorhynchus_tshawytschaENSOTSP0000507489698.251795.8042
ENSG00000198791homo_sapiensENSP0000035527935.789534.0351acanthochromis_polyacanthusENSAPOP0000003183698.076993.2692
ENSG00000198791homo_sapiensENSP0000035527998.947494.7368acanthochromis_polyacanthusENSAPOP0000000475298.601494.4056
ENSG00000198791homo_sapiensENSP00000355279100100aquila_chrysaetos_chrysaetosENSACCP00020011628100100
ENSG00000198791homo_sapiensENSP0000035527998.596594.7368nothobranchius_furzeriENSNFUP0001500464698.251794.4056
ENSG00000198791homo_sapiensENSP0000035527998.947494.0351cyprinodon_variegatusENSCVAP0000003029698.601493.7063
ENSG00000198791homo_sapiensENSP0000035527998.596595.4386denticeps_clupeoidesENSDCDP0000004351698.251795.1049
ENSG00000198791homo_sapiensENSP0000035527998.947494.7368larimichthys_croceaENSLCRP0000504915498.601494.4056
ENSG00000198791homo_sapiensENSP0000035527998.596593.6842takifugu_rubripesENSTRUP0000005223898.596593.6842
ENSG00000198791homo_sapiensENSP0000035527987.368487.0175ficedula_albicollisENSFALP0000001186587.062986.7133
ENSG00000198791homo_sapiensENSP0000035527935.789534.0351hippocampus_comesENSHCOP0000001849298.076993.2692
ENSG00000198791homo_sapiensENSP0000035527998.596596.1404cyprinus_carpio_carpioENSCCRP0000005015198.251795.8042
ENSG00000198791homo_sapiensENSP0000035527998.596595.7895cyprinus_carpio_carpioENSCCRP0000000811198.251795.4545
ENSG00000198791homo_sapiensENSP00000355279100100coturnix_japonicaENSCJPP00005012439100100
ENSG00000198791homo_sapiensENSP0000035527999.298295.4386poecilia_latipinnaENSPLAP0000000745398.95195.1049
ENSG00000198791homo_sapiensENSP0000035527947.368443.8596sinocyclocheilus_grahamiENSSGRP0000003322893.7586.8056
ENSG00000198791homo_sapiensENSP0000035527966.315861.7544sinocyclocheilus_grahamiENSSGRP0000003322785.135179.2793
ENSG00000198791homo_sapiensENSP0000035527998.245695.4386sinocyclocheilus_grahamiENSSGRP0000007249797.902195.1049
ENSG00000198791homo_sapiensENSP0000035527935.438634.386sinocyclocheilus_grahamiENSSGRP0000000774197.115494.2308
ENSG00000198791homo_sapiensENSP0000035527998.947494.7368maylandia_zebraENSMZEP0000500848998.601494.4056
ENSG00000198791homo_sapiensENSP0000035527999.649195.7895paramormyrops_kingsleyaeENSPKIP0000002197899.300795.4545
ENSG00000198791homo_sapiensENSP0000035527999.298296.1404scleropages_formosusENSSFOP0001502043598.95195.8042
ENSG00000198791homo_sapiensENSP0000035527987.719383.5088leptobrachium_leishanenseENSLLEP0000000450985.616481.5069
ENSG00000198791homo_sapiensENSP0000035527998.947494.7368scophthalmus_maximusENSSMAP0000005744898.601494.4056
ENSG00000198791homo_sapiensENSP0000035527998.245693.6842oryzias_melastigmaENSOMEP0000003072897.902193.3566

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000175enables 3-5-RNA exonuclease activity1IDAHomo_sapiens(9606)Function
GO:0000289involved_in nuclear-transcribed mRNA poly(A) tail shortening1NASHomo_sapiens(9606)Process
GO:0000290involved_in deadenylation-dependent decapping of nuclear-transcribed mRNA1IDAHomo_sapiens(9606)Process
GO:0000932is_active_in P-body2IBA,ISSHomo_sapiens(9606)Component
GO:0003714enables transcription corepressor activity1IMPHomo_sapiens(9606)Function
GO:0003723enables RNA binding1IEAHomo_sapiens(9606)Function
GO:0004532enables RNA exonuclease activity1IDAHomo_sapiens(9606)Function
GO:0004535enables poly(A)-specific ribonuclease activity2IBA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IMPHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0008284involved_in positive regulation of cell population proliferation1IMPHomo_sapiens(9606)Process
GO:0008285involved_in negative regulation of cell population proliferation1IDAHomo_sapiens(9606)Process
GO:0010629involved_in negative regulation of gene expression1IMPHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0016604located_in nuclear body1IDAHomo_sapiens(9606)Component
GO:0016607located_in nuclear speck1IMPHomo_sapiens(9606)Component
GO:0030014part_of CCR4-NOT complex2IDA,NASHomo_sapiens(9606)Component
GO:0030015part_of CCR4-NOT core complex1IBAHomo_sapiens(9606)Component
GO:0031047involved_in regulatory ncRNA-mediated gene silencing1ISSHomo_sapiens(9606)Process
GO:0033962involved_in P-body assembly1IEAHomo_sapiens(9606)Process
GO:0035195involved_in miRNA-mediated gene silencing1TASHomo_sapiens(9606)Process
GO:0042509involved_in regulation of tyrosine phosphorylation of STAT protein1IMPHomo_sapiens(9606)Process
GO:0043232is_active_in intracellular non-membrane-bounded organelle1IDAHomo_sapiens(9606)Component
GO:0043928involved_in exonucleolytic catabolism of deadenylated mRNA2IBA,IDAHomo_sapiens(9606)Process
GO:0045070involved_in positive regulation of viral genome replication1IMPHomo_sapiens(9606)Process
GO:0045892involved_in negative regulation of DNA-templated transcription1IMPHomo_sapiens(9606)Process
GO:0045944involved_in positive regulation of transcription by RNA polymerase II1IEAHomo_sapiens(9606)Process
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function
GO:0051607involved_in defense response to virus1IMPHomo_sapiens(9606)Process
GO:0060213involved_in positive regulation of nuclear-transcribed mRNA poly(A) tail shortening1IMPHomo_sapiens(9606)Process
GO:0060339involved_in negative regulation of type I interferon-mediated signaling pathway1IMPHomo_sapiens(9606)Process
GO:0061014involved_in positive regulation of mRNA catabolic process1IMPHomo_sapiens(9606)Process
GO:0140297enables DNA-binding transcription factor binding1IPIHomo_sapiens(9606)Function
GO:1900153involved_in positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay1IMPHomo_sapiens(9606)Process

Expression