Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerCHIKVFlavivirusesHIVRVSARS-COV-2SINVVEEVDengue
Drug Drug
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000196924 Gene ID 2316 Accession 3754
Symbol FLNA Alias FLN;FMD;MNS;OPD;ABPX;CSBS;CVD1;FGS2;FLN1;NHBP;OPD1;OPD2;XLVD;XMVD;FLN-A;ABP-280 Full Name filamin A
Status Confidence Length 26111 bases Strand Minus strand
Position X : 154348524 - 154374634 RNA binding domain N.A.
Summary The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
36806943 The force-dependent filamin A-G3BP1 interaction regulates phase-separated stress granule formation. Ziyi Feng 2023-03-15 Journal of cell science
37169020 Interaction of LARP4 to filamin A mechanosensing domain regulates cell migrations. Zhenfeng Mao 2023-01-01 Frontiers in cell and developmental biology

Transcripts

Name Transcript ID bp Protein Translation ID
FLNA-205 ENST00000420627 8225 604aa ENSP00000408921
FLNA-221 ENST00000678304 3982 No protein -
FLNA-206 ENST00000422373 5083 1574aa ENSP00000416926
FLNA-201 ENST00000360319 8278 2639aa ENSP00000353467
FLNA-216 ENST00000498411 368 No protein -
FLNA-203 ENST00000369856 8240 2620aa ENSP00000358872
FLNA-220 ENST00000676696 8541 556aa ENSP00000503392
FLNA-218 ENST00000610817 8319 482aa ENSP00000480593
FLNA-202 ENST00000369850 8507 2647aa ENSP00000358866
FLNA-219 ENST00000673639 435 96aa ENSP00000501210
FLNA-215 ENST00000490936 5374 No protein -
FLNA-217 ENST00000498491 914 No protein -
FLNA-209 ENST00000462590 1026 No protein -
FLNA-208 ENST00000444578 843 281aa ENSP00000397824
FLNA-214 ENST00000474358 696 No protein -
FLNA-212 ENST00000466325 828 No protein -
FLNA-204 ENST00000415241 704 90aa ENSP00000405458
FLNA-207 ENST00000438732 696 232aa ENSP00000398215
FLNA-213 ENST00000474072 430 No protein -
FLNA-211 ENST00000466319 460 No protein -
FLNA-210 ENST00000465144 398 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000196924homo_sapiensENSP000004508318.397283.88012homo_sapiensENSP0000035886621.911610.1247
ENSG00000196924homo_sapiensENSP0000047452929.204517.2727homo_sapiensENSP000003588669.70915.74235
ENSG00000196924homo_sapiensENSP0000044895544.236326.513homo_sapiensENSP0000035886611.5986.95127
ENSG00000196924homo_sapiensENSP0000034484813.08566.42182homo_sapiensENSP0000035886622.478311.0314
ENSG00000196924homo_sapiensENSP0000036912912.33025.32915homo_sapiensENSP0000035886613.37365.78013
ENSG00000196924homo_sapiensENSP0000035492317.93769.11805homo_sapiensENSP0000035886624.971712.6936
ENSG00000196924homo_sapiensENSP0000046924218.25279.24337homo_sapiensENSP0000035886617.68048.95353
ENSG00000196924homo_sapiensENSP0000049590921.091111.0825homo_sapiensENSP0000035886618.54939.74688
ENSG00000196924homo_sapiensENSP0000036182414.57415.53088homo_sapiensENSP0000035886613.63815.17567
ENSG00000196924homo_sapiensENSP0000041601516.18386.94306homo_sapiensENSP0000035886612.24035.25123
ENSG00000196924homo_sapiensENSP0000031779010.88735.25313homo_sapiensENSP0000035886615.11147.29127
ENSG00000196924homo_sapiensENSP000003601587.241043.60825homo_sapiensENSP0000035886611.14475.55346
ENSG00000196924homo_sapiensENSP0000050706717.61578.00712homo_sapiensENSP000003588667.480173.40008
ENSG00000196924homo_sapiensENSP0000025269943.688324.5884homo_sapiensENSP0000035886615.03598.46241
ENSG00000196924homo_sapiensENSP0000038408419.93629.2504homo_sapiensENSP000003588664.722332.19116
ENSG00000196924homo_sapiensENSP0000034925920.939110.4061homo_sapiensENSP0000035886618.70049.29354
ENSG00000196924homo_sapiensENSP000004844727.330983.67531homo_sapiensENSP0000035886614.09147.0646
ENSG00000196924homo_sapiensENSP0000036765517.6299.85152homo_sapiensENSP0000035886628.258415.7915
ENSG00000196924homo_sapiensENSP0000040581916.23387.92208homo_sapiensENSP000003588664.722332.3045
ENSG00000196924homo_sapiensENSP0000049521415.37836.32493homo_sapiensENSP0000035886614.05365.78013
ENSG00000196924homo_sapiensENSP0000039659321.97239.86159homo_sapiensENSP000003588664.797882.15338
ENSG00000196924homo_sapiensENSP0000043256820.334710.5858homo_sapiensENSP0000035886618.36049.55799
ENSG00000196924homo_sapiensENSP000005050985.986192.95472homo_sapiensENSP0000035886617.68048.72686
ENSG00000196924homo_sapiensENSP0000035651513.80726.02971homo_sapiensENSP0000035886617.90717.82017
ENSG00000196924homo_sapiensENSP0000037863527.899715.1515homo_sapiensENSP0000035886610.08695.4779
ENSG00000196924homo_sapiensENSP0000050750121.230810.359homo_sapiensENSP000003588667.820173.81564
ENSG00000196924homo_sapiensENSP0000037396444.251625.1627homo_sapiensENSP000003588667.706844.38232
ENSG00000196924homo_sapiensENSP0000035166419.306510.403homo_sapiensENSP000003588667.78244.19343
ENSG00000196924homo_sapiensENSP0000029595683.205270.2921homo_sapiensENSP0000035886681.790769.0971
ENSG00000196924homo_sapiensENSP000004552747.902053.86499homo_sapiensENSP0000035886622.553811.0314
ENSG00000196924homo_sapiensENSP000003562246.991023.29658homo_sapiensENSP0000035886623.233910.9558
ENSG00000196924homo_sapiensENSP0000037794144.748424.07homo_sapiensENSP0000035886615.45158.3113
ENSG00000196924homo_sapiensENSP0000035553745.30223.8255homo_sapiensENSP0000035886615.30038.04685
ENSG00000196924homo_sapiensENSP0000042679744.839124.4173homo_sapiensENSP0000035886615.26268.3113
ENSG00000196924homo_sapiensENSP0000029891225.349313.6727homo_sapiensENSP000003588669.595775.17567
ENSG00000196924homo_sapiensENSP0000032714582.311970.6422homo_sapiensENSP0000035886684.737472.7238

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000196924homo_sapiensENSP0000035886697.128896.411nomascus_leucogenysENSNLEP0000001714197.905697.182
ENSG00000196924homo_sapiensENSP0000035886680.770780.5062pan_paniscusENSPPAP0000000387197.714897.3949
ENSG00000196924homo_sapiensENSP0000035886699.962299.7355pongo_abeliiENSPPYP0000002336099.962299.7355
ENSG00000196924homo_sapiensENSP0000035886697.242296.9777pan_troglodytesENSPTRP0000006342094.946594.6883
ENSG00000196924homo_sapiensENSP0000035886699.886799.7355gorilla_gorillaENSGGOP0000000413699.886799.7355
ENSG00000196924homo_sapiensENSP0000035886693.842188.0997ornithorhynchus_anatinusENSOANP0000001745196.055790.1779
ENSG00000196924homo_sapiensENSP0000035886694.786689.4975sarcophilus_harrisiiENSSHAP0000000118294.500989.2279
ENSG00000196924homo_sapiensENSP0000035886690.177685.0019notamacropus_eugeniiENSMEUP0000000389190.79585.5839
ENSG00000196924homo_sapiensENSP0000035886690.706589.3087dasypus_novemcinctusENSDNOP0000002119093.715892.2717
ENSG00000196924homo_sapiensENSP0000035886677.672876.5395erinaceus_europaeusENSEEUP0000000547577.790476.6553
ENSG00000196924homo_sapiensENSP0000035886675.141773.6305echinops_telfairiENSETEP0000001185675.255473.742
ENSG00000196924homo_sapiensENSP0000035886699.3298.7533callithrix_jacchusENSCJAP0000003329899.24598.6787
ENSG00000196924homo_sapiensENSP0000035886699.735599.2444cercocebus_atysENSCATP0000003762099.735599.2444
ENSG00000196924homo_sapiensENSP0000035886699.735599.1689macaca_fascicularisENSMFAP0000002219598.802498.241
ENSG00000196924homo_sapiensENSP0000035886699.773399.32macaca_mulattaENSMMUP0000001798699.773399.32
ENSG00000196924homo_sapiensENSP0000035886699.735599.2822macaca_nemestrinaENSMNEP0000003805799.735599.2822
ENSG00000196924homo_sapiensENSP0000035886670.872770.5327papio_anubisENSPANP0000000156499.840399.3614
ENSG00000196924homo_sapiensENSP0000035886694.144393.1999mandrillus_leucophaeusENSMLEP0000002791897.15496.1793
ENSG00000196924homo_sapiensENSP0000035886693.162192.142tursiops_truncatusENSTTRP0000001320293.621992.5968
ENSG00000196924homo_sapiensENSP0000035886698.6497.9977vulpes_vulpesENSVVUP0000004155098.677298.0348
ENSG00000196924homo_sapiensENSP0000035886698.488997.3555mus_spretusMGP_SPRETEiJ_P009559398.488997.3555
ENSG00000196924homo_sapiensENSP0000035886698.715597.9977equus_asinusENSEASP0000502812298.715597.9977
ENSG00000196924homo_sapiensENSP0000035886698.488997.5066capra_hircusENSCHIP0000000794598.488997.5066
ENSG00000196924homo_sapiensENSP0000035886693.804393.1621loxodonta_africanaENSLAFP0000000534798.492797.8183
ENSG00000196924homo_sapiensENSP0000035886698.602297.8088panthera_leoENSPLOP0000001463398.602297.8088
ENSG00000196924homo_sapiensENSP0000035886698.488997.6955ailuropoda_melanoleucaENSAMEP0000000772298.488997.6955
ENSG00000196924homo_sapiensENSP0000035886698.337797.4311bos_indicus_hybridENSBIXP0000503277798.337797.4311
ENSG00000196924homo_sapiensENSP0000035886697.582296.8644oryctolagus_cuniculusENSOCUP0000000076198.700897.9748
ENSG00000196924homo_sapiensENSP0000035886698.753398.0355equus_caballusENSECAP0000000942998.753398.0355
ENSG00000196924homo_sapiensENSP0000035886698.677797.9222canis_lupus_familiarisENSCAFP0084503909698.71597.9592
ENSG00000196924homo_sapiensENSP0000035886698.6497.8466panthera_pardusENSPPRP0000001582998.6497.8466
ENSG00000196924homo_sapiensENSP0000035886681.639680.4685marmota_marmota_marmotaENSMMMP0000001602594.120292.77
ENSG00000196924homo_sapiensENSP0000035886698.715597.7711balaenoptera_musculusENSBMSP0001002897598.715597.7711
ENSG00000196924homo_sapiensENSP0000035886698.526697.5444cavia_porcellusENSCPOP0000002713798.601197.6181
ENSG00000196924homo_sapiensENSP0000035886698.564497.6955felis_catusENSFCAP0000003943992.913192.094
ENSG00000196924homo_sapiensENSP0000035886657.574656.6301ursus_americanusENSUAMP0000000288991.807290.3012
ENSG00000196924homo_sapiensENSP0000035886692.066586.7019monodelphis_domesticaENSMODP0000004446395.269789.7185
ENSG00000196924homo_sapiensENSP000003588665.515685.28901bison_bison_bisonENSBBBP0000001681879.347876.087
ENSG00000196924homo_sapiensENSP0000035886698.866697.7711monodon_monocerosENSMMNP0001501784498.866697.7711
ENSG00000196924homo_sapiensENSP0000035886697.431196.1844sus_scrofaENSSSCP0000004838889.023187.884
ENSG00000196924homo_sapiensENSP0000035886698.866697.8844microcebus_murinusENSMICP0000000425998.866697.8844
ENSG00000196924homo_sapiensENSP0000035886698.866697.5444octodon_degusENSODEP0000000536398.866697.5444
ENSG00000196924homo_sapiensENSP0000035886697.279996.2977jaculus_jaculusENSJJAP0000001250597.760196.773
ENSG00000196924homo_sapiensENSP0000035886698.413397.4688ovis_aries_rambouilletENSOARP0002002772998.413397.4688
ENSG00000196924homo_sapiensENSP0000035886691.008789.5731ursus_maritimusENSUMAP0000002846494.507793.0169
ENSG00000196924homo_sapiensENSP0000035886672.87571.8927ochotona_princepsENSOPRP0000001255977.345676.3031
ENSG00000196924homo_sapiensENSP0000035886698.866697.8088delphinapterus_leucasENSDLEP0000001494898.866697.8088
ENSG00000196924homo_sapiensENSP0000035886698.828997.7333physeter_catodonENSPCTP0000501843298.828997.7333
ENSG00000196924homo_sapiensENSP0000035886698.526697.3177mus_caroliMGP_CAROLIEiJ_P009183998.526697.3177
ENSG00000196924homo_sapiensENSP0000035886698.451197.3177mus_musculusENSMUSP0000003369998.451197.3177
ENSG00000196924homo_sapiensENSP0000035886698.564497.3933dipodomys_ordiiENSDORP0000001729498.564497.3933
ENSG00000196924homo_sapiensENSP0000035886698.564497.5066mustela_putorius_furoENSMPUP0000000921998.564497.5066
ENSG00000196924homo_sapiensENSP0000035886629.958429.6184aotus_nancymaaeENSANAP0000002644096.237995.1456
ENSG00000196924homo_sapiensENSP0000035886683.604183.1885aotus_nancymaaeENSANAP0000002287599.282298.7887
ENSG00000196924homo_sapiensENSP0000035886699.206698.7533saimiri_boliviensis_boliviensisENSSBOP0000003935899.206698.7533
ENSG00000196924homo_sapiensENSP0000035886699.395598.7911chlorocebus_sabaeusENSCSAP0000000305999.696999.0906
ENSG00000196924homo_sapiensENSP0000035886669.512768.7571tupaia_belangeriENSTBEP0000000986774.044373.2394
ENSG00000196924homo_sapiensENSP0000035886629.467328.9762mesocricetus_auratusENSMAUP0000001385495.588293.9951
ENSG00000196924homo_sapiensENSP0000035886698.753397.6577phocoena_sinusENSPSNP0000003073498.753397.6577
ENSG00000196924homo_sapiensENSP0000035886698.904498.0733camelus_dromedariusENSCDRP0000501685198.904498.0733
ENSG00000196924homo_sapiensENSP0000035886694.71194.1065carlito_syrichtaENSTSYP0000002029194.71194.1065
ENSG00000196924homo_sapiensENSP0000035886698.488997.3555rattus_norvegicusENSRNOP0000008203598.488997.3555
ENSG00000196924homo_sapiensENSP0000035886699.131198.6022prolemur_simusENSPSMP0000002168099.131198.6022
ENSG00000196924homo_sapiensENSP0000035886698.6497.5444microtus_ochrogasterENSMOCP0000000795898.6497.5444
ENSG00000196924homo_sapiensENSP0000035886683.528582.1307sorex_araneusENSSARP0000000356584.324982.9138
ENSG00000196924homo_sapiensENSP0000035886698.526697.2799peromyscus_maniculatus_bairdiiENSPEMP0000000772998.526697.2799
ENSG00000196924homo_sapiensENSP0000035886698.375597.4688bos_mutusENSBMUP0000001828498.375597.4688
ENSG00000196924homo_sapiensENSP0000035886631.280730.7518mus_spicilegusENSMSIP0000001646598.806797.136
ENSG00000196924homo_sapiensENSP0000035886698.488997.3177cricetulus_griseus_chok1gshdENSCGRP0000101168198.488997.3177
ENSG00000196924homo_sapiensENSP0000035886693.728893.0487pteropus_vampyrusENSPVAP0000000353793.906193.2248
ENSG00000196924homo_sapiensENSP0000035886697.9697.0155myotis_lucifugusENSMLUP0000001303798.443497.4943
ENSG00000196924homo_sapiensENSP0000035886694.748889.3087vombatus_ursinusENSVURP0001002437794.463389.0396
ENSG00000196924homo_sapiensENSP0000035886698.828998.0733rhinolophus_ferrumequinumENSRFEP0001000603698.828998.0733
ENSG00000196924homo_sapiensENSP0000035886698.6497.6577neovison_visonENSNVIP0000003100098.6497.6577
ENSG00000196924homo_sapiensENSP0000035886698.375597.4688bos_taurusENSBTAP0000003017998.375597.4688
ENSG00000196924homo_sapiensENSP0000035886630.03429.5807rhinopithecus_bietiENSRBIP0000003032197.069695.6044
ENSG00000196924homo_sapiensENSP0000035886695.806694.711canis_lupus_dingoENSCAFP0002002784695.123894.036
ENSG00000196924homo_sapiensENSP0000035886699.206698.4889sciurus_vulgarisENSSVLP0000502457999.206698.4889
ENSG00000196924homo_sapiensENSP0000035886694.106588.6664phascolarctos_cinereusENSPCIP0000003583795.14989.6486
ENSG00000196924homo_sapiensENSP0000035886696.373395.2399procavia_capensisENSPCAP0000001233896.592295.4563
ENSG00000196924homo_sapiensENSP0000035886699.131198.1111nannospalax_galiliENSNGAP0000001148899.131198.1111
ENSG00000196924homo_sapiensENSP0000035886698.397.3555bos_grunniensENSBGRP0000003754598.397.3555
ENSG00000196924homo_sapiensENSP0000035886698.526697.5444chinchilla_lanigeraENSCLAP0000000437198.825397.8401
ENSG00000196924homo_sapiensENSP0000035886698.6497.7333cervus_hanglu_yarkandensisENSCHYP0000003206998.6497.7333
ENSG00000196924homo_sapiensENSP0000035886699.093398.3755ictidomys_tridecemlineatusENSSTOP0000000458299.093398.3755
ENSG00000196924homo_sapiensENSP0000035886698.866698.0355otolemur_garnettiiENSOGAP0000001368698.866698.0355
ENSG00000196924homo_sapiensENSP0000035886680.657380.1662cebus_imitatorENSCCAP0000001888097.399696.8066
ENSG00000196924homo_sapiensENSP0000035886699.055598.3377urocitellus_parryiiENSUPAP0001000072999.055598.3377
ENSG00000196924homo_sapiensENSP0000035886698.715597.7711moschus_moschiferusENSMMSP0000002013698.715597.7711
ENSG00000196924homo_sapiensENSP0000035886699.697899.0933rhinopithecus_roxellanaENSRROP0000003620899.697899.0933
ENSG00000196924homo_sapiensENSP0000035886698.526697.2422mus_pahariMGP_PahariEiJ_P008946598.526697.2422
ENSG00000196924homo_sapiensENSP0000035886698.904498.1866propithecus_coquereliENSPCOP0000000372498.904498.1866
ENSG00000196924homo_sapiensENSP000003588666.00685.28901ciona_intestinalisENSCINP0000003062586.41376.087
ENSG00000196924homo_sapiensENSP0000035886664.072552.1723ciona_intestinalisENSCINP0000000674271.051557.855
ENSG00000196924homo_sapiensENSP000003588663.928983.28674petromyzon_marinusENSPMAP0000000723977.03764.4444
ENSG00000196924homo_sapiensENSP000003588665.47794.57121callorhinchus_miliiENSCMIP0000000502578.378465.4054
ENSG00000196924homo_sapiensENSP0000035886691.159882.8863latimeria_chalumnaeENSLACP0000000268791.505583.2006
ENSG00000196924homo_sapiensENSP0000035886688.175379.184lepisosteus_oculatusENSLOCP0000001908588.677879.6353
ENSG00000196924homo_sapiensENSP0000035886687.041977.6728clupea_harengusENSCHAP0000003093189.859680.1872
ENSG00000196924homo_sapiensENSP0000035886687.19378.3529danio_rerioENSDARP0000011380890.403581.2378
ENSG00000196924homo_sapiensENSP0000035886687.19378.1262carassius_auratusENSCARP0000013242588.125278.9614
ENSG00000196924homo_sapiensENSP0000035886687.19377.6728carassius_auratusENSCARP0000008735889.875480.0623
ENSG00000196924homo_sapiensENSP0000035886685.757576.8417astyanax_mexicanusENSAMXP0000001379990.402281.0036
ENSG00000196924homo_sapiensENSP0000035886686.890878.3906ictalurus_punctatusENSIPUP0000002849090.090181.2769
ENSG00000196924homo_sapiensENSP0000035886685.417475.9728esox_luciusENSELUP0000007202088.423978.6469
ENSG00000196924homo_sapiensENSP0000035886685.266376.0106oncorhynchus_kisutchENSOKIP0000510708188.718679.0881
ENSG00000196924homo_sapiensENSP0000035886683.679674.4239oncorhynchus_mykissENSOMYP0000001707085.455276.0031
ENSG00000196924homo_sapiensENSP0000035886680.128470.6082oncorhynchus_mykissENSOMYP0000011320582.754672.9224
ENSG00000196924homo_sapiensENSP0000035886682.319672.0816salmo_salarENSSSAP0000013515885.922775.2366
ENSG00000196924homo_sapiensENSP0000035886685.15375.8217salmo_salarENSSSAP0000005797886.825977.3112
ENSG00000196924homo_sapiensENSP0000035886685.644176.2373salmo_truttaENSSTUP0000002995288.210178.5214
ENSG00000196924homo_sapiensENSP0000035886673.252764.1481salmo_truttaENSSTUP0000001383985.531574.9007
ENSG00000196924homo_sapiensENSP0000035886685.417476.4639fundulus_heteroclitusENSFHEP0000002774189.438380.0633
ENSG00000196924homo_sapiensENSP0000035886685.984176.955poecilia_reticulataENSPREP0000000858989.500680.1022
ENSG00000196924homo_sapiensENSP0000035886684.81375.935xiphophorus_maculatusENSXMAP0000000479089.087379.7619
ENSG00000196924homo_sapiensENSP0000035886685.83376.6528oryzias_latipesENSORLP0000003700089.308279.7563
ENSG00000196924homo_sapiensENSP0000035886684.661976.1995oreochromis_niloticusENSONIP0000002258089.568380.6155
ENSG00000196924homo_sapiensENSP000003588664.193433.92898haplochromis_burtoniENSHBUP0000002203979.285774.2857
ENSG00000196924homo_sapiensENSP0000035886628.787326.2184haplochromis_burtoniENSHBUP0000002204591.91883.7153
ENSG00000196924homo_sapiensENSP0000035886629.127326.4828astatotilapia_callipteraENSACLP0000000061592.335383.9521
ENSG00000196924homo_sapiensENSP0000035886684.095275.0283sparus_aurataENSSAUP0001000124085.714376.4729
ENSG00000196924homo_sapiensENSP0000035886685.908677.2951lates_calcariferENSLCAP0001002935187.427978.6621
ENSG00000196924homo_sapiensENSP0000035886692.104385.4552xenopus_tropicalisENSXETP0000007307392.208885.5522
ENSG00000196924homo_sapiensENSP0000035886691.348784.5863chrysemys_picta_belliiENSCPBP0000002233392.714785.8512
ENSG00000196924homo_sapiensENSP0000035886628.069525.8784sphenodon_punctatusENSSPUP0000001902891.053983.9461
ENSG00000196924homo_sapiensENSP0000035886684.964178.504laticauda_laticaudataENSLLTP0000000053092.627785.5848
ENSG00000196924homo_sapiensENSP0000035886692.633285.3419notechis_scutatusENSNSUP0000002130291.595184.3855
ENSG00000196924homo_sapiensENSP0000035886693.162185.9841pseudonaja_textilisENSPTXP0000000685992.986485.822
ENSG00000196924homo_sapiensENSP0000035886692.935485.9086anolis_carolinensisENSACAP0000000999490.774983.9114
ENSG00000196924homo_sapiensENSP000003588664.533434.19343neolamprologus_brichardiENSNBRP0000000526081.632775.5102
ENSG00000196924homo_sapiensENSP0000035886622.856119.6449neolamprologus_brichardiENSNBRP0000000525184.615472.7273
ENSG00000196924homo_sapiensENSP0000035886629.127326.4828neolamprologus_brichardiENSNBRP0000000520992.335383.9521
ENSG00000196924homo_sapiensENSP0000035886691.688784.4352naja_najaENSNNAP0000002896292.211284.9164
ENSG00000196924homo_sapiensENSP0000035886693.199986.173podarcis_muralisENSPMRP0000003256092.814185.8164
ENSG00000196924homo_sapiensENSP0000035886686.021976.6528taeniopygia_guttataENSTGUP0000001934783.376174.2951
ENSG00000196924homo_sapiensENSP0000035886687.986480.0151erpetoichthys_calabaricusENSECRP0000002795290.693182.4766
ENSG00000196924homo_sapiensENSP0000035886628.976226.4073kryptolebias_marmoratusENSKMAP0000000680391.856383.7126
ENSG00000196924homo_sapiensENSP0000035886692.859886.0975salvator_merianaeENSSMRP0000000290192.719785.9676
ENSG00000196924homo_sapiensENSP0000035886685.984176.8039amphilophus_citrinellusENSACIP0000000773289.924980.324
ENSG00000196924homo_sapiensENSP0000035886686.059776.9173dicentrarchus_labraxENSDLAP0000505094688.810979.3762
ENSG00000196924homo_sapiensENSP0000035886681.412972.8372amphiprion_perculaENSAPEP0000002516490.660581.1106
ENSG00000196924homo_sapiensENSP000003588662.908952.68228pelodiscus_sinensisENSPSIP0000000907887.580.6818
ENSG00000196924homo_sapiensENSP000003588667.78246.76237pelodiscus_sinensisENSPSIP0000000908987.659676.1702
ENSG00000196924homo_sapiensENSP0000035886684.284177.3328gopherus_evgoodeiENSGEVP0000502832888.112280.8452
ENSG00000196924homo_sapiensENSP0000035886684.170877.2951chelonoidis_abingdoniiENSCABP0000003091586.089679.0572
ENSG00000196924homo_sapiensENSP0000035886684.019675.3683seriola_dumeriliENSSDUP0000001886489.102679.9279
ENSG00000196924homo_sapiensENSP0000035886685.266375.935cottoperca_gobioENSCGOP0000002789785.850176.4549
ENSG00000196924homo_sapiensENSP0000035886617.491516.0559gasterosteus_aculeatusENSGACP0000001733591.683284.1584
ENSG00000196924homo_sapiensENSP0000035886635.927531.6585gasterosteus_aculeatusENSGACP0000001732489.128478.538
ENSG00000196924homo_sapiensENSP0000035886686.210877.6728cynoglossus_semilaevisENSCSEP0000000490089.701380.8176
ENSG00000196924homo_sapiensENSP0000035886686.097577.0684poecilia_formosaENSPFOP0000000191489.618680.2202
ENSG00000196924homo_sapiensENSP0000035886684.321975.5572myripristis_murdjanENSMMDP0000505066287.221678.1555
ENSG00000196924homo_sapiensENSP0000035886686.059777.0306sander_luciopercaENSSLUP0000003282385.929876.9144
ENSG00000196924homo_sapiensENSP0000035886683.301874.5372amphiprion_ocellarisENSAOCP0000002889290.703481.16
ENSG00000196924homo_sapiensENSP000003588663.17342.98451hucho_huchoENSHHUP0000002609890.322684.9462
ENSG00000196924homo_sapiensENSP0000035886674.688366.6415pygocentrus_nattereriENSPNAP0000002867689.53879.8913
ENSG00000196924homo_sapiensENSP0000035886685.984177.3328anabas_testudineusENSATEP0000006654688.457179.5569
ENSG00000196924homo_sapiensENSP0000035886656.214644.881ciona_savignyiENSCSAVP0000001757768.698154.8476
ENSG00000196924homo_sapiensENSP0000035886611.97589.82244ciona_savignyiENSCSAVP0000001785359.031748.4171
ENSG00000196924homo_sapiensENSP0000035886680.430771.9683seriola_lalandi_dorsalisENSSLDP0000000171489.378779.9748
ENSG00000196924homo_sapiensENSP0000035886684.095274.6128labrus_bergyltaENSLBEP0000001469190.857180.6122
ENSG00000196924homo_sapiensENSP0000035886628.787326.2184pundamilia_nyerereiENSPNYP0000003193991.91883.7153
ENSG00000196924homo_sapiensENSP000003588666.00685.36456pundamilia_nyerereiENSPNYP0000003194178.325169.9507
ENSG00000196924homo_sapiensENSP000003588664.533434.15565pundamilia_nyerereiENSPNYP0000003194381.632774.8299
ENSG00000196924homo_sapiensENSP0000035886686.777577.7484mastacembelus_armatusENSMAMP0000002337590.255480.8644
ENSG00000196924homo_sapiensENSP0000035886685.530876.5017stegastes_partitusENSSPAP0000000061290.814381.2274
ENSG00000196924homo_sapiensENSP000003588664.760113.77786oncorhynchus_tshawytschaENSOTSP0000504153263.959450.7614
ENSG00000196924homo_sapiensENSP0000035886626.10523.5739oncorhynchus_tshawytschaENSOTSP0000508483990.091381.3559
ENSG00000196924homo_sapiensENSP0000035886629.01426.2939acanthochromis_polyacanthusENSAPOP0000003101791.976183.3533
ENSG00000196924homo_sapiensENSP000003588664.042313.81564acanthochromis_polyacanthusENSAPOP0000000638783.593878.9062
ENSG00000196924homo_sapiensENSP000003588664.306763.96675cyprinodon_variegatusENSCVAP0000000947188.372181.3953
ENSG00000196924homo_sapiensENSP000003588666.913496.08236cyprinodon_variegatusENSCVAP0000000956285.51475.2336
ENSG00000196924homo_sapiensENSP0000035886654.590147.7522cyprinodon_variegatusENSCVAP0000002613985.705874.9703
ENSG00000196924homo_sapiensENSP0000035886686.966478.0884denticeps_clupeoidesENSDCDP0000002487290.380881.1543
ENSG00000196924homo_sapiensENSP0000035886686.361977.3706larimichthys_croceaENSLCRP0000505057487.318678.2277
ENSG00000196924homo_sapiensENSP0000035886626.558423.7628hippocampus_comesENSHCOP0000001159387.437878.2338
ENSG00000196924homo_sapiensENSP0000035886687.495378.5417cyprinus_carpio_carpioENSCCRP0000007965290.716881.4336
ENSG00000196924homo_sapiensENSP0000035886687.268678.2395cyprinus_carpio_carpioENSCCRP0000015422490.730681.3433
ENSG00000196924homo_sapiensENSP0000035886651.001142.0854coturnix_japonicaENSCJPP0000500319864.408453.1489
ENSG00000196924homo_sapiensENSP000003588664.080093.8912poecilia_latipinnaENSPLAP0000002836783.720979.845
ENSG00000196924homo_sapiensENSP0000035886628.862926.0672poecilia_latipinnaENSPLAP0000001404791.387682.5359
ENSG00000196924homo_sapiensENSP0000035886686.097577.0684sinocyclocheilus_grahamiENSSGRP0000005095088.780779.4702
ENSG00000196924homo_sapiensENSP000003588665.175674.19343sinocyclocheilus_grahamiENSSGRP0000000527486.708970.2532
ENSG00000196924homo_sapiensENSP0000035886686.550877.1062sinocyclocheilus_grahamiENSSGRP0000004904289.109379.3855
ENSG00000196924homo_sapiensENSP0000035886628.67426.0672maylandia_zebraENSMZEP0000503551092.223683.8396
ENSG00000196924homo_sapiensENSP000003588664.533434.15565maylandia_zebraENSMZEP0000503551181.632774.8299
ENSG00000196924homo_sapiensENSP000003588664.495664.11787tetraodon_nigroviridisENSTNIP0000000438896.74888.6179
ENSG00000196924homo_sapiensENSP0000035886687.079778.0128paramormyrops_kingsleyaeENSPKIP0000002279390.534281.1076
ENSG00000196924homo_sapiensENSP0000035886684.359675.5195scleropages_formosusENSSFOP0001505056985.785676.796
ENSG00000196924homo_sapiensENSP0000035886689.384282.1685leptobrachium_leishanenseENSLLEP0000004721692.857185.3611
ENSG00000196924homo_sapiensENSP0000035886684.624175.4061scophthalmus_maximusENSSMAP0000000278487.465877.9383
ENSG00000196924homo_sapiensENSP0000035886628.862926.0295oryzias_melastigmaENSOMEP0000001036991.49782.515
ENSG00000196924homo_sapiensENSP000003588664.268984.00453oryzias_melastigmaENSOMEP0000002855280.141875.1773
ENSG00000196924homo_sapiensENSP000003588666.800155.70457oryzias_melastigmaENSOMEP0000001038681.818268.6364

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0001525involved_in angiogenesis1IEAHomo_sapiens(9606)Process
GO:0001664enables G protein-coupled receptor binding1IPIHomo_sapiens(9606)Function
GO:0001837involved_in epithelial to mesenchymal transition1IEAHomo_sapiens(9606)Process
GO:0001974involved_in blood vessel remodeling1IEAHomo_sapiens(9606)Process
GO:0003007involved_in heart morphogenesis1IEAHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0005080enables protein kinase C binding1IEAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005576located_in extracellular region1TASHomo_sapiens(9606)Component
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005730located_in nucleolus1IMPHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005802located_in trans-Golgi network1IEAHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0005884located_in actin filament1IEAHomo_sapiens(9606)Component
GO:0005886located_in plasma membrane1IDAHomo_sapiens(9606)Component
GO:0005903located_in brush border1IEAHomo_sapiens(9606)Component
GO:0005911located_in cell-cell junction1IDAHomo_sapiens(9606)Component
GO:0005925located_in focal adhesion1HDAHomo_sapiens(9606)Component
GO:0007195involved_in adenylate cyclase-inhibiting dopamine receptor signaling pathway1IMPHomo_sapiens(9606)Process
GO:0007597involved_in blood coagulation, intrinsic pathway1NASHomo_sapiens(9606)Process
GO:0010572involved_in positive regulation of platelet activation1NASHomo_sapiens(9606)Process
GO:0010977involved_in negative regulation of neuron projection development1IEAHomo_sapiens(9606)Process
GO:0015459enables potassium channel regulator activity1IDAHomo_sapiens(9606)Function
GO:0015629located_in actin cytoskeleton2IC,IDAHomo_sapiens(9606)Component
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0016479involved_in negative regulation of transcription by RNA polymerase I1IDAHomo_sapiens(9606)Process
GO:0019900enables kinase binding1IPIHomo_sapiens(9606)Function
GO:0021943involved_in formation of radial glial scaffolds1IEAHomo_sapiens(9606)Process
GO:0021987involved_in cerebral cortex development1IEAHomo_sapiens(9606)Process
GO:0030018located_in Z disc1ISSHomo_sapiens(9606)Component
GO:0030036involved_in actin cytoskeleton organization1IDAHomo_sapiens(9606)Process
GO:0030334involved_in regulation of cell migration1IDAHomo_sapiens(9606)Process
GO:0030863located_in cortical cytoskeleton1IEAHomo_sapiens(9606)Component
GO:0031267enables small GTPase binding1IDAHomo_sapiens(9606)Function
GO:0031523part_of Myb complex1IDAHomo_sapiens(9606)Component
GO:0032233involved_in positive regulation of actin filament bundle assembly1IEAHomo_sapiens(9606)Process
GO:0032432located_in actin filament bundle1IEAHomo_sapiens(9606)Component
GO:0034394involved_in protein localization to cell surface1IDAHomo_sapiens(9606)Process
GO:0034988enables Fc-gamma receptor I complex binding1IDAHomo_sapiens(9606)Function
GO:0035855involved_in megakaryocyte development1NASHomo_sapiens(9606)Process
GO:0042177involved_in negative regulation of protein catabolic process1IMPHomo_sapiens(9606)Process
GO:0042307involved_in positive regulation of protein import into nucleus1IMPHomo_sapiens(9606)Process
GO:0042789involved_in mRNA transcription by RNA polymerase II1IEAHomo_sapiens(9606)Process
GO:0042803enables protein homodimerization activity1IDAHomo_sapiens(9606)Function
GO:0043066involved_in negative regulation of apoptotic process1IMPHomo_sapiens(9606)Process
GO:0043113involved_in receptor clustering1IDAHomo_sapiens(9606)Process
GO:0043123involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling1HMPHomo_sapiens(9606)Process
GO:0043198located_in dendritic shaft1IEAHomo_sapiens(9606)Component
GO:0043204located_in perikaryon1IEAHomo_sapiens(9606)Component
GO:0043433involved_in negative regulation of DNA-binding transcription factor activity1IDAHomo_sapiens(9606)Process
GO:0044295located_in axonal growth cone1IEAHomo_sapiens(9606)Component
GO:0044319involved_in wound healing, spreading of cells1IDAHomo_sapiens(9606)Process
GO:0044325enables transmembrane transporter binding1IPIHomo_sapiens(9606)Function
GO:0045022involved_in early endosome to late endosome transport1IEAHomo_sapiens(9606)Process
GO:0045184involved_in establishment of protein localization1IDAHomo_sapiens(9606)Process
GO:0045216involved_in cell-cell junction organization1IEAHomo_sapiens(9606)Process
GO:0045296enables cadherin binding1HDAHomo_sapiens(9606)Function
GO:0046332enables SMAD binding1IEAHomo_sapiens(9606)Function
GO:0048471located_in perinuclear region of cytoplasm1IEAHomo_sapiens(9606)Component
GO:0048680involved_in positive regulation of axon regeneration1IEAHomo_sapiens(9606)Process
GO:0050808involved_in synapse organization1IEAHomo_sapiens(9606)Process
GO:0050821involved_in protein stabilization1IMPHomo_sapiens(9606)Process
GO:0051015enables actin filament binding1IDAHomo_sapiens(9606)Function
GO:0051020enables GTPase binding1IPIHomo_sapiens(9606)Function
GO:0051209involved_in release of sequestered calcium ion into cytosol1NASHomo_sapiens(9606)Process
GO:0051220involved_in cytoplasmic sequestering of protein1IMPHomo_sapiens(9606)Process
GO:0051764involved_in actin crosslink formation1IDAHomo_sapiens(9606)Process
GO:0060271involved_in cilium assembly1IMPHomo_sapiens(9606)Process
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component
GO:0070527involved_in platelet aggregation1HMPHomo_sapiens(9606)Process
GO:0071526involved_in semaphorin-plexin signaling pathway1IGIHomo_sapiens(9606)Process
GO:0072659involved_in protein localization to plasma membrane1IDAHomo_sapiens(9606)Process
GO:0090042involved_in tubulin deacetylation1IMPHomo_sapiens(9606)Process
GO:0090307acts_upstream_of_or_within mitotic spindle assembly1IDAHomo_sapiens(9606)Process
GO:0097368involved_in establishment of Sertoli cell barrier1IEAHomo_sapiens(9606)Process
GO:0097440located_in apical dendrite1IEAHomo_sapiens(9606)Component
GO:0098794located_in postsynapse1IEAHomo_sapiens(9606)Component
GO:0098978located_in glutamatergic synapse1IEAHomo_sapiens(9606)Component
GO:0140297enables DNA-binding transcription factor binding1IPIHomo_sapiens(9606)Function
GO:1900026involved_in positive regulation of substrate adhesion-dependent cell spreading1IMPHomo_sapiens(9606)Process
GO:1901381involved_in positive regulation of potassium ion transmembrane transport1IDAHomo_sapiens(9606)Process
GO:1902396involved_in protein localization to bicellular tight junction1IEAHomo_sapiens(9606)Process
GO:1905000involved_in regulation of membrane repolarization during atrial cardiac muscle cell action potential1ICHomo_sapiens(9606)Process
GO:1905031involved_in regulation of membrane repolarization during cardiac muscle cell action potential1ISSHomo_sapiens(9606)Process
GO:1990779part_of glycoprotein Ib-IX-V complex1NASHomo_sapiens(9606)Component
GO:2000179involved_in positive regulation of neural precursor cell proliferation1IEAHomo_sapiens(9606)Process
GO:2001046involved_in positive regulation of integrin-mediated signaling pathway1IMPHomo_sapiens(9606)Process
GO:2001224involved_in positive regulation of neuron migration1IEAHomo_sapiens(9606)Process

Expression