Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations P-body
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000185650 Gene ID 677 Accession 1107
Symbol ZFP36L1 Alias BRF1;ERF1;cMG1;ERF-1;Berg36;TIS11B;RNF162B Full Name ZFP36 ring finger protein like 1
Status Confidence Length 8592 bases Strand Minus strand
Position 14 : 68787662 - 68796253 RNA binding domain zf-CCCH , zf-CCCH_2
Summary This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000450600 zf-CCCH PF00642 8.7e-23 1
ENSP00000450600 zf-CCCH PF00642 8.7e-23 2
ENSP00000450600 zf-CCCH_2 PF14608 7e-06 3
ENSP00000450600 zf-CCCH_2 PF14608 7e-06 4
ENSP00000450784 zf-CCCH PF00642 1.4e-22 1
ENSP00000450784 zf-CCCH PF00642 1.4e-22 2
ENSP00000450784 zf-CCCH_2 PF14608 1.1e-05 3
ENSP00000450784 zf-CCCH_2 PF14608 1.1e-05 4
ENSP00000337386 zf-CCCH PF00642 8.3e-22 1
ENSP00000337386 zf-CCCH PF00642 8.3e-22 2
ENSP00000337386 zf-CCCH_2 PF14608 3.6e-05 3
ENSP00000337386 zf-CCCH_2 PF14608 3.6e-05 4
ENSP00000388402 zf-CCCH PF00642 8.3e-22 1
ENSP00000388402 zf-CCCH PF00642 8.3e-22 2
ENSP00000388402 zf-CCCH_2 PF14608 3.6e-05 3
ENSP00000388402 zf-CCCH_2 PF14608 3.6e-05 4

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
32687160 Nuclear accumulation of ZFP36L1 is cell cycle-dependent and determined by a C-terminal serine-rich cluster. Yuki Matsuura 2020-11-01 Journal of biochemistry
36963393 A miR-124-mediated post-transcriptional mechanism controlling the cell fate switch of astrocytes to induced neurons. Elsa Papadimitriou 2023-04-11 Stem cell reports
29993187 Levamisole suppresses adipogenesis of aplastic anaemia-derived bone marrow mesenchymal stem cells through ZFP36L1-PPARGC1B axis. Lu-Lu Liu 2018-09-01 Journal of cellular and molecular medicine
34643435 Zinc Finger Protein ZFP36L1 Inhibits Flavivirus Infection by both 5'-3' XRN1 and 3'-5' RNA-Exosome RNA Decay Pathways. Han Chiu 2022-01-12 Journal of virology
31999936 Overexpression of microRNA-129-5p in glioblastoma inhibits cell proliferation, migration, and colony-forming ability by targeting ZFP36L1. Xu Guo 2020-11-02 Bosnian journal of basic medical sciences
22903503 Identification of a novel flow-mediated gene expression signature in patients with bicuspid aortic valve. Shohreh Maleki 2013-01-01 Journal of molecular medicine (Berlin, Germany)
27102483 RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence. Alison Galloway 2016-04-22 Science (New York, N.Y.)
33427197 Use of signals of positive and negative selection to distinguish cancer genes and passenger genes. László Bányai 2021-01-11 eLife
35611776 ZFP36L1 Promotes Gastric Cancer Progression via Regulating JNK and p38 MAPK Signaling Pathways. Kang Ding 2023-01-01 Recent patents on anti-cancer drug discovery
32556261 Zinc finger protein ZFP36L1 inhibits influenza A virus through translational repression by targeting HA, M and NS RNA transcripts. Ren-Jye Lin 2020-07-27 Nucleic acids research
31551365 RNA-Binding Protein ZFP36L1 Suppresses Hypoxia and Cell-Cycle Signaling. Xin-Yi Loh 2020-01-15 Cancer research
30755618 Whole-genome sequencing identifies ADGRG6 enhancer mutations and FRS2 duplications as angiogenesis-related drivers in bladder cancer. Song Wu 2019-02-12 Nature communications
36100056 Silencing of RNA binding protein, ZFP36L1, promotes epithelial-mesenchymal transition in liver cancer cells by regulating transcription factor ZEB2. Jian Chen 2022-09-12 Cellular signalling
33711487 Proteomic analysis of Laodelphax striatellus in response to Rice stripe virus infection reveal a potential role of ZFP36L1 in restriction of viral proliferation. Hai-Jian Huang 2021-05-15 Journal of proteomics
35642067 The multifaceted role of the SASP in atherosclerosis: from mechanisms to therapeutic opportunities. Yu Sun 2022-05-31 Cell & bioscience
29257272 High expression of FLT3 is a risk factor in leukemia. Jie Cheng 2018-02-01 Molecular medicine reports
30777893 Quantification and discovery of sequence determinants of protein-per-mRNA amount in 29 human tissues. Basak Eraslan 2019-02-18 Molecular systems biology
36008402 Regulation of neuroendocrine plasticity by the RNA-binding protein ZFP36L1. Hsiao-Yun Chen 2022-08-25 Nature communications
29868023 The Interplay Between Innate-Like B Cells and Other Cell Types in Autoimmunity. J Gregory Tsay 2018-01-01 Frontiers in immunology
30622281 RNA-binding protein ZFP36L1 regulates osteoarthritis by modulating members of the heat shock protein 70 family. Young-Ok Son 2019-01-08 Nature communications
37355988 Understanding heterogeneity of human bone marrow plasma cell maturation and survival pathways by single-cell analyses. Meixue Duan 2023-07-25 Cell reports
35318269 Killing SCLC: insights into how to target a shapeshifting tumor. D Kate Sutherland 2022-03-01 Genes & development
34540682 Brain Microenvironment Heterogeneity: Potential Value for Brain Tumors. Laura Álvaro-Espinosa 2021-01-01 Frontiers in oncology
34295816 The RNA-Binding Protein NELFE Promotes Gastric Cancer Growth and Metastasis Through E2F2. Changyu Chen 2021-01-01 Frontiers in oncology
33397444 Comprehensive integrative profiling of upper tract urothelial carcinomas. Xiaoping Su 2021-01-04 Genome biology
36685529 Comprehensive bulk and single-cell transcriptome profiling give useful insights into the characteristics of osteoarthritis associated synovial macrophages. Shengyou Liao 2022-01-01 Frontiers in immunology

Transcripts

Name Transcript ID bp Protein Translation ID
ZFP36L1-204 ENST00000555997 3094 No protein -
ZFP36L1-202 ENST00000439696 3017 338aa ENSP00000388402
ZFP36L1-201 ENST00000336440 4539 338aa ENSP00000337386
ZFP36L1-206 ENST00000557086 727 207aa ENSP00000450784
ZFP36L1-205 ENST00000557022 577 176aa ENSP00000450600
ZFP36L1-203 ENST00000553375 633 189aa ENSP00000452119

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
46502Platelet Function Tests1.2086900E-005-
62247Age-Related Hearing Impairment 18E-924939585
66389Inflammatory Bowel Diseases1E-826192919
73285Diabetes Mellitus, Type 12E-1219430480
83688Fibrinogen1E-823969696
83748Fibrinogen4E-1328107422
85688Inflammatory Bowel Diseases3E-1023128233
99278Crohn Disease1E-726192919
99791Fibrinogen8E-1428107422
101561Fibrinogen2E-1226561523
101901Celiac Disease4E-720190752
104772Multiple Sclerosis9E-1221833088

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000185650homo_sapiensENSP0000028238846.761140.081homo_sapiensENSP0000038840268.343258.5799
ENSG00000185650homo_sapiensENSP0000046964739.263832.8221homo_sapiensENSP0000038840237.869831.6568

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000185650homo_sapiensENSP0000038840210099.7041nomascus_leucogenysENSNLEP0000000122510099.7041
ENSG00000185650homo_sapiensENSP0000038840299.704199.7041pan_paniscusENSPPAP0000000843699.704199.7041
ENSG00000185650homo_sapiensENSP0000038840210099.7041pongo_abeliiENSPPYP0000000674410099.7041
ENSG00000185650homo_sapiensENSP0000038840299.704199.7041pan_troglodytesENSPTRP0000006144299.704199.7041
ENSG00000185650homo_sapiensENSP00000388402100100gorilla_gorillaENSGGOP00000034936100100
ENSG00000185650homo_sapiensENSP0000038840293.195390.5325ornithorhynchus_anatinusENSOANP0000004506693.7591.0714
ENSG00000185650homo_sapiensENSP0000038840293.491191.4201sarcophilus_harrisiiENSSHAP0000002797176.69975
ENSG00000185650homo_sapiensENSP0000038840296.153894.9704notamacropus_eugeniiENSMEUP0000000279796.153894.9704
ENSG00000185650homo_sapiensENSP0000038840276.035575.7396dasypus_novemcinctusENSDNOP0000000399198.467498.0843
ENSG00000185650homo_sapiensENSP0000038840299.408399.4083callithrix_jacchusENSCJAP0000007403699.408399.4083
ENSG00000185650homo_sapiensENSP0000038840299.408399.4083cercocebus_atysENSCATP0000004169799.408399.4083
ENSG00000185650homo_sapiensENSP0000038840299.704199.7041macaca_fascicularisENSMFAP0000006180599.704199.7041
ENSG00000185650homo_sapiensENSP0000038840295.562194.9704macaca_mulattaENSMMUP0000004760593.895393.314
ENSG00000185650homo_sapiensENSP0000038840298.224997.929macaca_nemestrinaENSMNEP0000001721398.224997.929
ENSG00000185650homo_sapiensENSP0000038840299.704199.7041papio_anubisENSPANP0000001713699.704199.7041
ENSG00000185650homo_sapiensENSP0000038840299.408399.4083mandrillus_leucophaeusENSMLEP0000004046299.408399.4083
ENSG00000185650homo_sapiensENSP0000038840299.112499.1124tursiops_truncatusENSTTRP0000000325799.112499.1124
ENSG00000185650homo_sapiensENSP0000038840299.112497.929vulpes_vulpesENSVVUP0000000453199.112497.929
ENSG00000185650homo_sapiensENSP0000038840298.816698.5207mus_spretusMGP_SPRETEiJ_P003416398.816698.5207
ENSG00000185650homo_sapiensENSP0000038840298.816698.8166equus_asinusENSEASP0000506188198.816698.8166
ENSG00000185650homo_sapiensENSP0000038840299.112499.1124capra_hircusENSCHIP0000002633999.112499.1124
ENSG00000185650homo_sapiensENSP0000038840298.816698.5207loxodonta_africanaENSLAFP0000002601598.816698.5207
ENSG00000185650homo_sapiensENSP0000038840299.112498.8166panthera_leoENSPLOP0000002061499.112498.8166
ENSG00000185650homo_sapiensENSP0000038840289.053388.4615ailuropoda_melanoleucaENSAMEP0000002729876.590376.0814
ENSG00000185650homo_sapiensENSP0000038840294.674694.6746bos_indicus_hybridENSBIXP0000500097799.071299.0712
ENSG00000185650homo_sapiensENSP0000038840242.011837.8698oryctolagus_cuniculusENSOCUP0000003721569.607862.7451
ENSG00000185650homo_sapiensENSP0000038840298.816698.8166equus_caballusENSECAP0000001639098.816698.8166
ENSG00000185650homo_sapiensENSP0000038840299.408398.2249canis_lupus_familiarisENSCAFP0084500526899.408398.2249
ENSG00000185650homo_sapiensENSP0000038840299.408399.1124panthera_pardusENSPPRP0000002489199.408399.1124
ENSG00000185650homo_sapiensENSP0000038840299.408399.4083marmota_marmota_marmotaENSMMMP0000000049099.408399.4083
ENSG00000185650homo_sapiensENSP0000038840299.408399.4083balaenoptera_musculusENSBMSP0001000259599.408399.4083
ENSG00000185650homo_sapiensENSP0000038840299.112498.5207cavia_porcellusENSCPOP0000002870799.112498.5207
ENSG00000185650homo_sapiensENSP0000038840299.408399.1124felis_catusENSFCAP0000002383199.408399.1124
ENSG00000185650homo_sapiensENSP0000038840299.408399.1124ursus_americanusENSUAMP0000001336599.408399.1124
ENSG00000185650homo_sapiensENSP0000038840287.57485.503monodelphis_domesticaENSMODP0000001267494.267592.0382
ENSG00000185650homo_sapiensENSP0000038840299.112499.1124monodon_monocerosENSMMNP0001501783999.112499.1124
ENSG00000185650homo_sapiensENSP0000038840297.633195.2663sus_scrofaENSSSCP0000006003694.827692.5287
ENSG00000185650homo_sapiensENSP0000038840299.112499.1124microcebus_murinusENSMICP0000003642499.112499.1124
ENSG00000185650homo_sapiensENSP0000038840298.816698.5207octodon_degusENSODEP0000001919998.816698.5207
ENSG00000185650homo_sapiensENSP0000038840292.899492.0118jaculus_jaculusENSJJAP0000001490591.545290.6706
ENSG00000185650homo_sapiensENSP0000038840299.112499.1124ovis_aries_rambouilletENSOARP0002000454399.112499.1124
ENSG00000185650homo_sapiensENSP0000038840299.408399.1124ursus_maritimusENSUMAP0000001375399.408399.1124
ENSG00000185650homo_sapiensENSP0000038840261.834358.284ochotona_princepsENSOPRP0000000550066.349262.5397
ENSG00000185650homo_sapiensENSP0000038840299.112499.1124delphinapterus_leucasENSDLEP0000001585099.112499.1124
ENSG00000185650homo_sapiensENSP0000038840299.112499.1124physeter_catodonENSPCTP0000502172799.112499.1124
ENSG00000185650homo_sapiensENSP0000038840298.816698.5207mus_caroliMGP_CAROLIEiJ_P003265598.816698.5207
ENSG00000185650homo_sapiensENSP0000038840298.816698.5207mus_musculusENSMUSP0000002155298.816698.5207
ENSG00000185650homo_sapiensENSP0000038840299.408398.8166dipodomys_ordiiENSDORP0000001605799.408398.8166
ENSG00000185650homo_sapiensENSP0000038840292.603692.3077mustela_putorius_furoENSMPUP0000000722598.738298.4227
ENSG00000185650homo_sapiensENSP0000038840299.408399.4083aotus_nancymaaeENSANAP0000003947899.408399.4083
ENSG00000185650homo_sapiensENSP0000038840299.704199.7041saimiri_boliviensis_boliviensisENSSBOP0000001808599.704199.7041
ENSG00000185650homo_sapiensENSP0000038840299.704199.7041chlorocebus_sabaeusENSCSAP0000000929099.704199.7041
ENSG00000185650homo_sapiensENSP0000038840299.112498.8166mesocricetus_auratusENSMAUP0000002273499.112498.8166
ENSG00000185650homo_sapiensENSP0000038840299.112499.1124phocoena_sinusENSPSNP0000001067499.112499.1124
ENSG00000185650homo_sapiensENSP0000038840299.408399.1124camelus_dromedariusENSCDRP0000500426199.408399.1124
ENSG00000185650homo_sapiensENSP0000038840298.224998.2249carlito_syrichtaENSTSYP0000003329298.224998.2249
ENSG00000185650homo_sapiensENSP0000038840287.278186.6864panthera_tigris_altaicaENSPTIP0000002229898.006697.3422
ENSG00000185650homo_sapiensENSP0000038840298.520798.5207rattus_norvegicusENSRNOP0000007541298.520798.5207
ENSG00000185650homo_sapiensENSP0000038840299.112499.1124prolemur_simusENSPSMP0000001587999.112499.1124
ENSG00000185650homo_sapiensENSP0000038840299.112498.5207microtus_ochrogasterENSMOCP0000000398399.112498.5207
ENSG00000185650homo_sapiensENSP0000038840299.112498.5207peromyscus_maniculatus_bairdiiENSPEMP0000001035099.112498.5207
ENSG00000185650homo_sapiensENSP0000038840299.112499.1124bos_mutusENSBMUP0000001685099.112499.1124
ENSG00000185650homo_sapiensENSP0000038840261.242660.9467mus_spicilegusENSMSIP0000000201598.571498.0952
ENSG00000185650homo_sapiensENSP0000038840299.112498.8166cricetulus_griseus_chok1gshdENSCGRP0000100868599.112498.8166
ENSG00000185650homo_sapiensENSP0000038840293.195392.3077pteropus_vampyrusENSPVAP0000001101798.746197.8056
ENSG00000185650homo_sapiensENSP0000038840295.562194.3787vombatus_ursinusENSVURP0001003055395.562194.3787
ENSG00000185650homo_sapiensENSP0000038840299.112499.1124rhinolophus_ferrumequinumENSRFEP0001000725599.112499.1124
ENSG00000185650homo_sapiensENSP0000038840299.112499.1124neovison_visonENSNVIP0000001213599.112499.1124
ENSG00000185650homo_sapiensENSP0000038840299.112499.1124bos_taurusENSBTAP0000003561199.112499.1124
ENSG00000185650homo_sapiensENSP0000038840298.816698.5207heterocephalus_glaber_femaleENSHGLP0000004685498.816698.5207
ENSG00000185650homo_sapiensENSP0000038840294.970494.3787rhinopithecus_bietiENSRBIP0000003350098.165197.5535
ENSG00000185650homo_sapiensENSP0000038840299.408398.2249canis_lupus_dingoENSCAFP0002000734499.408398.2249
ENSG00000185650homo_sapiensENSP0000038840299.408399.4083sciurus_vulgarisENSSVLP0000501646499.408399.4083
ENSG00000185650homo_sapiensENSP0000038840293.491191.4201phascolarctos_cinereusENSPCIP000000511788078.2279
ENSG00000185650homo_sapiensENSP0000038840299.112499.1124procavia_capensisENSPCAP0000000497299.112499.1124
ENSG00000185650homo_sapiensENSP0000038840299.112498.8166nannospalax_galiliENSNGAP0000002685499.112498.8166
ENSG00000185650homo_sapiensENSP0000038840299.112499.1124bos_grunniensENSBGRP0000001048499.112499.1124
ENSG00000185650homo_sapiensENSP0000038840298.816698.2249chinchilla_lanigeraENSCLAP0000000520698.816698.2249
ENSG00000185650homo_sapiensENSP0000038840299.112498.8166cervus_hanglu_yarkandensisENSCHYP0000001999199.112498.8166
ENSG00000185650homo_sapiensENSP0000038840299.408399.4083catagonus_wagneriENSCWAP0000002950199.408399.4083
ENSG00000185650homo_sapiensENSP0000038840299.408399.4083ictidomys_tridecemlineatusENSSTOP0000000874599.408399.4083
ENSG00000185650homo_sapiensENSP0000038840297.92997.929otolemur_garnettiiENSOGAP0000000896497.92997.929
ENSG00000185650homo_sapiensENSP0000038840299.704199.7041cebus_imitatorENSCCAP0000000116999.704199.7041
ENSG00000185650homo_sapiensENSP0000038840298.520798.5207urocitellus_parryiiENSUPAP0001001540397.368497.3684
ENSG00000185650homo_sapiensENSP0000038840299.112499.1124moschus_moschiferusENSMMSP0000001972499.112499.1124
ENSG00000185650homo_sapiensENSP0000038840299.704199.7041rhinopithecus_roxellanaENSRROP0000003407099.704199.7041
ENSG00000185650homo_sapiensENSP0000038840298.816698.5207mus_pahariMGP_PahariEiJ_P008276598.816698.5207
ENSG00000185650homo_sapiensENSP0000038840299.112498.8166propithecus_coquereliENSPCOP0000002105299.112498.8166
ENSG00000185650homo_sapiensENSP0000038840225.739617.1598caenorhabditis_elegansF52E1.1.132.954521.9697
ENSG00000185650homo_sapiensENSP0000038840221.301815.0888caenorhabditis_elegansY60A9.3.135.46825.1232
ENSG00000185650homo_sapiensENSP0000038840223.668616.2722caenorhabditis_elegansY116A8C.17.139.024426.8293
ENSG00000185650homo_sapiensENSP0000038840223.668617.1598caenorhabditis_elegansF38C2.5.143.010831.1828
ENSG00000185650homo_sapiensENSP0000038840220.710114.497caenorhabditis_elegansC35D6.4.134.482824.1379
ENSG00000185650homo_sapiensENSP0000038840223.372816.2722caenorhabditis_elegansY116A8C.20.139.303527.3632
ENSG00000185650homo_sapiensENSP0000038840221.597615.0888caenorhabditis_elegansY116A8C.19.137.244926.0204
ENSG00000185650homo_sapiensENSP0000038840221.301814.7929caenorhabditis_elegansF38C2.7.135.46824.6305
ENSG00000185650homo_sapiensENSP0000038840222.781115.3846caenorhabditis_elegansY57G11C.25.138.693526.1307
ENSG00000185650homo_sapiensENSP0000038840226.035516.568caenorhabditis_elegansW02A2.7.118.803411.9658
ENSG00000185650homo_sapiensENSP0000038840225.443815.9763caenorhabditis_elegansAH6.5.118.415411.5632
ENSG00000185650homo_sapiensENSP0000038840228.402419.2308caenorhabditis_elegansC09G9.6.123.587215.9705
ENSG00000185650homo_sapiensENSP0000038840230.177518.9349caenorhabditis_elegansF32A11.6.127.792917.4387
ENSG00000185650homo_sapiensENSP0000038840228.698217.7515caenorhabditis_elegansZC513.6.124.681915.2672
ENSG00000185650homo_sapiensENSP0000038840241.124328.4024caenorhabditis_elegansF38B7.1a.130.217420.8696
ENSG00000185650homo_sapiensENSP0000038840212.72197.39645caenorhabditis_elegansF02E11.4.131.159418.1159
ENSG00000185650homo_sapiensENSP0000038840213.01787.98817caenorhabditis_elegansY110A2AL.1.130.985919.0141
ENSG00000185650homo_sapiensENSP0000038840210.05926.50888caenorhabditis_elegansY110A2AL.10.130.630619.8198
ENSG00000185650homo_sapiensENSP0000038840236.390524.5562caenorhabditis_elegansT02E1.3b.118.114912.2239
ENSG00000185650homo_sapiensENSP0000038840274.852163.3136callorhinchus_miliiENSCMIP0000003881077.846265.8462
ENSG00000185650homo_sapiensENSP0000038840279.881770.4142latimeria_chalumnaeENSLACP0000002212378.034768.7861
ENSG00000185650homo_sapiensENSP0000038840276.035566.8639lepisosteus_oculatusENSLOCP0000001720971.787763.1285
ENSG00000185650homo_sapiensENSP0000038840275.739665.6805danio_rerioENSDARP0000002520568.449259.3583
ENSG00000185650homo_sapiensENSP0000038840272.781163.0177danio_rerioENSDARP0000001115070.689761.2069
ENSG00000185650homo_sapiensENSP0000038840275.443865.9763carassius_auratusENSCARP0000007646368.364659.7855
ENSG00000185650homo_sapiensENSP0000038840271.597660.9467carassius_auratusENSCARP0000010251768.945958.6895
ENSG00000185650homo_sapiensENSP0000038840271.301860.355carassius_auratusENSCARP0000012368162.435252.8497
ENSG00000185650homo_sapiensENSP0000038840271.005960.355carassius_auratusENSCARP0000002358468.965558.6207
ENSG00000185650homo_sapiensENSP0000038840275.739666.2722carassius_auratusENSCARP0000011963268.632760.0536
ENSG00000185650homo_sapiensENSP0000038840276.035566.568astyanax_mexicanusENSAMXP0000005412268.716660.1604
ENSG00000185650homo_sapiensENSP0000038840267.751556.8047astyanax_mexicanusENSAMXP0000004837067.352956.4706
ENSG00000185650homo_sapiensENSP0000038840275.147965.3846ictalurus_punctatusENSIPUP0000003531768.279659.4086
ENSG00000185650homo_sapiensENSP0000038840273.372865.3846esox_luciusENSELUP0000000795967.208759.8916
ENSG00000185650homo_sapiensENSP0000038840276.331466.8639esox_luciusENSELUP0000002255765.316557.2152
ENSG00000185650homo_sapiensENSP0000038840260.650952.9586electrophorus_electricusENSEEEP0000001330371.180662.1528
ENSG00000185650homo_sapiensENSP0000038840261.538551.4793electrophorus_electricusENSEEEP0000002279359.259349.5727
ENSG00000185650homo_sapiensENSP0000038840272.781163.6095oncorhynchus_kisutchENSOKIP0000503146162.121254.2929
ENSG00000185650homo_sapiensENSP0000038840275.443866.2722oncorhynchus_kisutchENSOKIP0000511114058.086651.0251
ENSG00000185650homo_sapiensENSP0000038840274.556265.3846oncorhynchus_kisutchENSOKIP0000503585965.796357.7024
ENSG00000185650homo_sapiensENSP0000038840268.934960.6509oncorhynchus_kisutchENSOKIP0000507741767.34159.2486
ENSG00000185650homo_sapiensENSP0000038840272.781163.9053oncorhynchus_mykissENSOMYP0000006566666.666758.5366
ENSG00000185650homo_sapiensENSP0000038840274.556266.2722oncorhynchus_mykissENSOMYP0000006295664.948557.732
ENSG00000185650homo_sapiensENSP0000038840275.443866.2722oncorhynchus_mykissENSOMYP0000008050961.004853.5885
ENSG00000185650homo_sapiensENSP0000038840269.526660.9467oncorhynchus_mykissENSOMYP0000001603368.31459.8837
ENSG00000185650homo_sapiensENSP0000038840273.076964.7929salmo_salarENSSSAP0000014467958.669852.019
ENSG00000185650homo_sapiensENSP0000038840274.852165.3846salmo_salarENSSSAP0000016667664.050655.9494
ENSG00000185650homo_sapiensENSP0000038840274.556265.3846salmo_salarENSSSAP0000012865364.615456.6667
ENSG00000185650homo_sapiensENSP0000038840269.526660.9467salmo_salarENSSSAP0000012680059.94952.551
ENSG00000185650homo_sapiensENSP0000038840274.556265.3846salmo_truttaENSSTUP0000011024965.796357.7024
ENSG00000185650homo_sapiensENSP0000038840274.852165.0888salmo_truttaENSSTUP0000003748254.525947.4138
ENSG00000185650homo_sapiensENSP0000038840269.230860.355salmo_truttaENSSTUP0000008952367.826159.1304
ENSG00000185650homo_sapiensENSP0000038840273.372865.3846salmo_truttaENSSTUP0000011427867.208759.8916
ENSG00000185650homo_sapiensENSP0000038840271.893563.6095gadus_morhuaENSGMOP0000003763955.733949.3119
ENSG00000185650homo_sapiensENSP0000038840272.485262.7219fundulus_heteroclitusENSFHEP0000002154066.939957.9235
ENSG00000185650homo_sapiensENSP0000038840272.485262.7219poecilia_reticulataENSPREP0000001992668.435859.2179
ENSG00000185650homo_sapiensENSP0000038840273.076962.7219xiphophorus_maculatusENSXMAP0000002374966.576857.1429
ENSG00000185650homo_sapiensENSP0000038840274.260464.2012oryzias_latipesENSORLP0000004418468.579259.2896
ENSG00000185650homo_sapiensENSP0000038840268.343257.3965cyclopterus_lumpusENSCLMP0000501526064.705954.3417
ENSG00000185650homo_sapiensENSP0000038840271.301861.8343cyclopterus_lumpusENSCLMP0000502362165.489156.7935
ENSG00000185650homo_sapiensENSP0000038840274.852162.7219oreochromis_niloticusENSONIP0000003109268.010756.9892
ENSG00000185650homo_sapiensENSP0000038840274.852162.7219haplochromis_burtoniENSHBUP0000003079668.010756.9892
ENSG00000185650homo_sapiensENSP0000038840274.852162.7219astatotilapia_callipteraENSACLP0000001134868.010756.9892
ENSG00000185650homo_sapiensENSP0000038840276.035566.2722sparus_aurataENSSAUP0001006858157.366150
ENSG00000185650homo_sapiensENSP0000038840267.159856.8047sparus_aurataENSSAUP0001000607263.943754.0845
ENSG00000185650homo_sapiensENSP0000038840271.893561.5385lates_calcariferENSLCAP0001002556667.877158.1006
ENSG00000185650homo_sapiensENSP0000038840274.852164.497lates_calcariferENSLCAP0001000454159.952651.6588
ENSG00000185650homo_sapiensENSP0000038840281.360972.7811xenopus_tropicalisENSXETP0000003700785.139376.161
ENSG00000185650homo_sapiensENSP0000038840291.124387.2781chrysemys_picta_belliiENSCPBP0000003056191.940388.0597
ENSG00000185650homo_sapiensENSP0000038840292.011887.2781sphenodon_punctatusENSSPUP0000000264192.559587.7976
ENSG00000185650homo_sapiensENSP0000038840292.899489.9408crocodylus_porosusENSCPRP0000502536193.731390.7463
ENSG00000185650homo_sapiensENSP0000038840289.053384.6154laticauda_laticaudataENSLLTP0000000841889.583385.119
ENSG00000185650homo_sapiensENSP0000038840289.349184.9112notechis_scutatusENSNSUP0000002447389.88185.4167
ENSG00000185650homo_sapiensENSP0000038840289.053384.6154pseudonaja_textilisENSPTXP0000001759489.583385.119
ENSG00000185650homo_sapiensENSP0000038840291.124387.574anas_platyrhynchos_platyrhynchosENSAPLP0000003242591.940388.3582
ENSG00000185650homo_sapiensENSP0000038840291.124387.2781gallus_gallusENSGALP0001002931791.940388.0597
ENSG00000185650homo_sapiensENSP0000038840286.390582.5444meleagris_gallopavoENSMGAP0000002053692.405188.2911
ENSG00000185650homo_sapiensENSP0000038840274.260470.1183serinus_canariaENSSCAP0000001820985.084780.339
ENSG00000185650homo_sapiensENSP0000038840291.124387.8698parus_majorENSPMJP0000002021491.940388.6567
ENSG00000185650homo_sapiensENSP0000038840274.852162.7219neolamprologus_brichardiENSNBRP0000001400468.010756.9892
ENSG00000185650homo_sapiensENSP0000038840289.64585.2071naja_najaENSNNAP0000001853190.178685.7143
ENSG00000185650homo_sapiensENSP0000038840290.532586.9822podarcis_muralisENSPMRP0000000530791.071487.5
ENSG00000185650homo_sapiensENSP0000038840291.71688.1657taeniopygia_guttataENSTGUP0000003063092.537388.9552
ENSG00000185650homo_sapiensENSP0000038840276.331469.2308erpetoichthys_calabaricusENSECRP0000002432372.881466.1017
ENSG00000185650homo_sapiensENSP0000038840274.260463.3136kryptolebias_marmoratusENSKMAP0000001763668.767158.6301
ENSG00000185650homo_sapiensENSP0000038840290.532585.503salvator_merianaeENSSMRP0000001223191.071486.0119
ENSG00000185650homo_sapiensENSP0000038840274.260464.497oryzias_javanicusENSOJAP0000003268468.206559.2391
ENSG00000185650homo_sapiensENSP0000038840273.076962.7219amphilophus_citrinellusENSACIP0000002099271.802361.6279
ENSG00000185650homo_sapiensENSP0000038840274.852164.7929dicentrarchus_labraxENSDLAP0000502979068.7559.5109
ENSG00000185650homo_sapiensENSP0000038840268.934960.9467dicentrarchus_labraxENSDLAP0000507940063.143655.8266
ENSG00000185650homo_sapiensENSP0000038840274.852164.497amphiprion_perculaENSAPEP0000001436268.010758.6021
ENSG00000185650homo_sapiensENSP0000038840274.260464.2012oryzias_sinensisENSOSIP0000002064468.579259.2896
ENSG00000185650homo_sapiensENSP0000038840292.603689.0533pelodiscus_sinensisENSPSIP0000000895293.432889.8507
ENSG00000185650homo_sapiensENSP0000038840291.124387.2781gopherus_evgoodeiENSGEVP0000502418692.215688.3234
ENSG00000185650homo_sapiensENSP0000038840290.828486.6864chelonoidis_abingdoniiENSCABP0000002304891.641887.4627
ENSG00000185650homo_sapiensENSP0000038840274.556264.497seriola_dumeriliENSSDUP0000001331867.741958.6021
ENSG00000185650homo_sapiensENSP0000038840268.343259.1716seriola_dumeriliENSSDUP0000000126964.887656.1798
ENSG00000185650homo_sapiensENSP0000038840275.147964.497cottoperca_gobioENSCGOP0000005332768.648758.9189
ENSG00000185650homo_sapiensENSP0000038840271.301861.5385cottoperca_gobioENSCGOP0000000801866.944457.7778
ENSG00000185650homo_sapiensENSP0000038840277.218974.5562anser_brachyrhynchusENSABRP0000001785693.884990.6475
ENSG00000185650homo_sapiensENSP0000038840274.852164.2012gasterosteus_aculeatusENSGACP0000001489567.287257.7128
ENSG00000185650homo_sapiensENSP0000038840274.260463.9053cynoglossus_semilaevisENSCSEP0000001097567.112357.754
ENSG00000185650homo_sapiensENSP0000038840272.485262.1302poecilia_formosaENSPFOP0000002528365.683656.3003
ENSG00000185650homo_sapiensENSP0000038840273.668665.0888myripristis_murdjanENSMMDP0000502200570.33962.1469
ENSG00000185650homo_sapiensENSP0000038840275.443865.6805myripristis_murdjanENSMMDP0000505464968.364659.5174
ENSG00000185650homo_sapiensENSP0000038840276.035565.3846sander_luciopercaENSSLUP0000003504268.900859.2493
ENSG00000185650homo_sapiensENSP0000038840269.526658.284sander_luciopercaENSSLUP0000003504965.642555.0279
ENSG00000185650homo_sapiensENSP0000038840291.124387.574strigops_habroptilaENSSHBP0000502319491.940388.3582
ENSG00000185650homo_sapiensENSP0000038840274.852164.497amphiprion_ocellarisENSAOCP0000002913168.010758.6021
ENSG00000185650homo_sapiensENSP0000038840291.124387.2781terrapene_carolina_triunguisENSTMTP0000001107691.940388.0597
ENSG00000185650homo_sapiensENSP0000038840275.443865.0888hucho_huchoENSHHUP0000008131664.231755.4156
ENSG00000185650homo_sapiensENSP0000038840272.781164.2012hucho_huchoENSHHUP0000005603356.551749.8851
ENSG00000185650homo_sapiensENSP0000038840273.964565.0888hucho_huchoENSHHUP0000007008265.104257.2917
ENSG00000185650homo_sapiensENSP0000038840269.230860.0592hucho_huchoENSHHUP0000005270967.630158.6705
ENSG00000185650homo_sapiensENSP0000038840274.260465.3846betta_splendensENSBSLP0000005411368.206560.0543
ENSG00000185650homo_sapiensENSP0000038840263.017752.6627betta_splendensENSBSLP0000002711164.93954.2683
ENSG00000185650homo_sapiensENSP0000038840266.56857.6923pygocentrus_nattereriENSPNAP0000002312166.964358.0357
ENSG00000185650homo_sapiensENSP0000038840276.035566.568pygocentrus_nattereriENSPNAP0000001020468.716660.1604
ENSG00000185650homo_sapiensENSP0000038840274.852164.497anabas_testudineusENSATEP0000000643168.010758.6021
ENSG00000185650homo_sapiensENSP0000038840270.118360.9467anabas_testudineusENSATEP0000002019766.57357.8652
ENSG00000185650homo_sapiensENSP0000038840274.556264.497seriola_lalandi_dorsalisENSSLDP0000002756467.741958.6021
ENSG00000185650homo_sapiensENSP0000038840266.863957.9882seriola_lalandi_dorsalisENSSLDP0000001385463.483155.0562
ENSG00000185650homo_sapiensENSP0000038840272.189362.7219labrus_bergyltaENSLBEP0000001048164.893656.383
ENSG00000185650homo_sapiensENSP0000038840274.852162.7219pundamilia_nyerereiENSPNYP0000000643168.194157.1429
ENSG00000185650homo_sapiensENSP0000038840274.556264.497mastacembelus_armatusENSMAMP0000000040660.287152.1531
ENSG00000185650homo_sapiensENSP0000038840275.147964.7929stegastes_partitusENSSPAP0000001370068.279658.871
ENSG00000185650homo_sapiensENSP0000038840273.076964.2012oncorhynchus_tshawytschaENSOTSP0000501118966.937758.8076
ENSG00000185650homo_sapiensENSP0000038840273.076964.2012oncorhynchus_tshawytschaENSOTSP0000506038166.937758.8076
ENSG00000185650homo_sapiensENSP0000038840274.556265.3846oncorhynchus_tshawytschaENSOTSP0000509077565.796357.7024
ENSG00000185650homo_sapiensENSP0000038840269.230860.9467oncorhynchus_tshawytschaENSOTSP0000502004067.630159.5376
ENSG00000185650homo_sapiensENSP0000038840275.443866.568oncorhynchus_tshawytschaENSOTSP0000501367163.7556.25
ENSG00000185650homo_sapiensENSP0000038840274.852164.497acanthochromis_polyacanthusENSAPOP0000001770667.828458.445
ENSG00000185650homo_sapiensENSP0000038840290.828487.574aquila_chrysaetos_chrysaetosENSACCP0002000618491.641888.3582
ENSG00000185650homo_sapiensENSP0000038840275.147963.6095nothobranchius_furzeriENSNFUP0001504330868.834758.2656
ENSG00000185650homo_sapiensENSP0000038840273.076963.3136cyprinodon_variegatusENSCVAP0000002441667.119658.1522
ENSG00000185650homo_sapiensENSP0000038840268.047358.5799denticeps_clupeoidesENSDCDP0000000362966.666757.3913
ENSG00000185650homo_sapiensENSP0000038840274.852165.0888larimichthys_croceaENSLCRP0000501802168.010759.1398
ENSG00000185650homo_sapiensENSP0000038840264.201255.0296larimichthys_croceaENSLCRP0000503716364.970155.6886
ENSG00000185650homo_sapiensENSP0000038840274.852164.497takifugu_rubripesENSTRUP0000008053159.112150.9346
ENSG00000185650homo_sapiensENSP0000038840286.390583.1361ficedula_albicollisENSFALP0000001576192.405188.924
ENSG00000185650homo_sapiensENSP0000038840239.349135.2071hippocampus_comesENSHCOP0000002387166.169259.204
ENSG00000185650homo_sapiensENSP0000038840274.852166.2722hippocampus_comesENSHCOP0000001116868.194160.3774
ENSG00000185650homo_sapiensENSP0000038840274.556265.0888cyprinus_carpio_carpioENSCCRP0000017357261.613753.7897
ENSG00000185650homo_sapiensENSP0000038840272.189361.2426cyprinus_carpio_carpioENSCCRP0000015867670.114959.4828
ENSG00000185650homo_sapiensENSP0000038840275.739666.568cyprinus_carpio_carpioENSCCRP0000016635468.632760.3217
ENSG00000185650homo_sapiensENSP0000038840272.189361.8343cyprinus_carpio_carpioENSCCRP0000012569769.515759.5442
ENSG00000185650homo_sapiensENSP0000038840291.124387.2781coturnix_japonicaENSCJPP0000502195491.940388.0597
ENSG00000185650homo_sapiensENSP0000038840272.189361.8343poecilia_latipinnaENSPLAP0000000403667.966658.2173
ENSG00000185650homo_sapiensENSP0000038840273.372862.1302sinocyclocheilus_grahamiENSSGRP0000001605170.655359.8291
ENSG00000185650homo_sapiensENSP0000038840275.443865.6805sinocyclocheilus_grahamiENSSGRP0000000697468.364659.5174
ENSG00000185650homo_sapiensENSP0000038840275.443866.2722sinocyclocheilus_grahamiENSSGRP0000000362568.548460.2151
ENSG00000185650homo_sapiensENSP0000038840274.852162.7219maylandia_zebraENSMZEP0000501955468.010756.9892
ENSG00000185650homo_sapiensENSP0000038840273.372863.3136tetraodon_nigroviridisENSTNIP0000000474672.727362.7566
ENSG00000185650homo_sapiensENSP0000038840275.147965.3846paramormyrops_kingsleyaeENSPKIP0000002744371.348362.0787
ENSG00000185650homo_sapiensENSP0000038840273.668665.9763paramormyrops_kingsleyaeENSPKIP0000002380868.975161.7729
ENSG00000185650homo_sapiensENSP0000038840272.781163.6095scleropages_formosusENSSFOP0001506688166.847858.4239
ENSG00000185650homo_sapiensENSP0000038840276.331467.4556scleropages_formosusENSSFOP0001504720470.879162.6374
ENSG00000185650homo_sapiensENSP0000038840258.28448.5207scophthalmus_maximusENSSMAP0000002969859.69749.697
ENSG00000185650homo_sapiensENSP0000038840273.372863.6095scophthalmus_maximusENSSMAP0000005376564.921556.2827
ENSG00000185650homo_sapiensENSP0000038840274.260464.497oryzias_melastigmaENSOMEP0000001664867.837858.9189

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000165involved_in MAPK cascade1IDAHomo_sapiens(9606)Process
GO:0000288involved_in nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay1IEAHomo_sapiens(9606)Process
GO:0000932located_in P-body1IDAHomo_sapiens(9606)Component
GO:0001570involved_in vasculogenesis1IEAHomo_sapiens(9606)Process
GO:0003342involved_in proepicardium development1IEAHomo_sapiens(9606)Process
GO:0003677enables DNA binding1IEAHomo_sapiens(9606)Function
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003729enables mRNA binding1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0006397involved_in mRNA processing1IEAHomo_sapiens(9606)Process
GO:0006915involved_in apoptotic process1IEAHomo_sapiens(9606)Process
GO:0007507involved_in heart development1IEAHomo_sapiens(9606)Process
GO:0008283involved_in cell population proliferation1IEAHomo_sapiens(9606)Process
GO:0009611involved_in response to wounding1IDAHomo_sapiens(9606)Process
GO:0010468involved_in regulation of gene expression1IDAHomo_sapiens(9606)Process
GO:0010837involved_in regulation of keratinocyte proliferation1IMPHomo_sapiens(9606)Process
GO:0014065involved_in phosphatidylinositol 3-kinase signaling1IDAHomo_sapiens(9606)Process
GO:0021915involved_in neural tube development1IEAHomo_sapiens(9606)Process
GO:0031086involved_in nuclear-transcribed mRNA catabolic process, deadenylation-independent decay1ISSHomo_sapiens(9606)Process
GO:0031440involved_in regulation of mRNA 3-end processing1IDAHomo_sapiens(9606)Process
GO:0032869involved_in cellular response to insulin stimulus1IDAHomo_sapiens(9606)Process
GO:0033077involved_in T cell differentiation in thymus1ISSHomo_sapiens(9606)Process
GO:0035264involved_in multicellular organism growth1IEAHomo_sapiens(9606)Process
GO:0035925enables mRNA 3-UTR AU-rich region binding1IDAHomo_sapiens(9606)Function
GO:0038066involved_in p38MAPK cascade1ISSHomo_sapiens(9606)Process
GO:0043488acts_upstream_of_or_within regulation of mRNA stability3IDA,IMPHomo_sapiens(9606)Process
GO:0043491involved_in protein kinase B signaling1ISSHomo_sapiens(9606)Process
GO:0044344involved_in cellular response to fibroblast growth factor stimulus1ISSHomo_sapiens(9606)Process
GO:0045577involved_in regulation of B cell differentiation1ISSHomo_sapiens(9606)Process
GO:0045600involved_in positive regulation of fat cell differentiation1ISSHomo_sapiens(9606)Process
GO:0045616involved_in regulation of keratinocyte differentiation1IMPHomo_sapiens(9606)Process
GO:0045647involved_in negative regulation of erythrocyte differentiation1IDAHomo_sapiens(9606)Process
GO:0045657involved_in positive regulation of monocyte differentiation1IDAHomo_sapiens(9606)Process
GO:0045661involved_in regulation of myoblast differentiation1ISSHomo_sapiens(9606)Process
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function
GO:0048382involved_in mesendoderm development1ISSHomo_sapiens(9606)Process
GO:0051028involved_in mRNA transport1IMPHomo_sapiens(9606)Process
GO:0060710involved_in chorio-allantoic fusion1IEAHomo_sapiens(9606)Process
GO:0061158involved_in 3-UTR-mediated mRNA destabilization2IDA,IMPHomo_sapiens(9606)Process
GO:0070371involved_in ERK1 and ERK2 cascade1IDAHomo_sapiens(9606)Process
GO:0071320involved_in cellular response to cAMP1IDAHomo_sapiens(9606)Process
GO:0071356involved_in cellular response to tumor necrosis factor1IDAHomo_sapiens(9606)Process
GO:0071364involved_in cellular response to epidermal growth factor stimulus1IDAHomo_sapiens(9606)Process
GO:0071375involved_in cellular response to peptide hormone stimulus1IDAHomo_sapiens(9606)Process
GO:0071385involved_in cellular response to glucocorticoid stimulus1IDAHomo_sapiens(9606)Process
GO:0071456involved_in cellular response to hypoxia1IMPHomo_sapiens(9606)Process
GO:0071472involved_in cellular response to salt stress1ISSHomo_sapiens(9606)Process
GO:0071560involved_in cellular response to transforming growth factor beta stimulus1IDAHomo_sapiens(9606)Process
GO:0071889enables 14-3-3 protein binding1IDAHomo_sapiens(9606)Function
GO:0072091involved_in regulation of stem cell proliferation1ISSHomo_sapiens(9606)Process
GO:0097403involved_in cellular response to raffinose1ISSHomo_sapiens(9606)Process
GO:1900153involved_in positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay1ISSHomo_sapiens(9606)Process
GO:1901991involved_in negative regulation of mitotic cell cycle phase transition1ISSHomo_sapiens(9606)Process
GO:1902172involved_in regulation of keratinocyte apoptotic process1IMPHomo_sapiens(9606)Process
GO:1904582involved_in positive regulation of intracellular mRNA localization1IMPHomo_sapiens(9606)Process
GO:1990904part_of ribonucleoprotein complex1IDAHomo_sapiens(9606)Component

Expression