Ensembl ID
ENSG00000185650
Gene ID
677
Accession
1107
Gene Symbol
ZFP36L1
Alias
BRF1;ERF1;cMG1;ERF-1;Berg36;TIS11B;RNF162B
Full Name
ZFP36 ring finger protein like 1
Position
14 : 68787662 - 68796253
Length
8592 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
ENSG00000185650 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000185650
ZFP36L1
-0.6
2.94e-20
BRCA
ENSG00000185650
ZFP36L1
-0.9
1.55e-18
PRAD
ENSG00000185650
ZFP36L1
-1.1
9.50e-31
LIHC
ENSG00000185650
ZFP36L1
-0.7
3.40e-11
STAD
ENSG00000185650
ZFP36L1
-1.0
9.30e-15
UCEC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000185650
ZFP36L1
breast cancer
15128281
ENSG00000185650
ZFP36L1
tumor
17058241
ENSG00000185650
ZFP36L1
renal cancer
19801654
ENSG00000185650
ZFP36L1
tumor
20802528
ENSG00000185650
ZFP36L1
tumour
25014217
ENSG00000185650
ZFP36L1
tumour
26280535
ENSG00000185650
ZFP36L1
acute myeloid leukemia (AML)
26542173
ENSG00000185650
ZFP36L1
tumors
28591699
ENSG00000185650
ZFP36L1
tumor
28882690
ENSG00000185650
ZFP36L1
colorectal cancer
29426877
ENSG00000185650
ZFP36L1
cancers
29531215
ENSG00000185650
ZFP36L1
tumor
30655376
ENSG00000185650
ZFP36L1
cancer
31551365
ENSG00000185650
ZFP36L1
breast cancer
9113991
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000185650
ZFP36L1
SARC
0.04
high
show
ENSG00000185650
ZFP36L1
STAD
0.0035
high
show
ENSG00000185650
ZFP36L1
CHOL
0.015
high
show
ENSG00000185650
ZFP36L1
UVM
0.04
low
show
ENSG00000185650
ZFP36L1
PAAD
0.00013
high
show
ENSG00000185650
ZFP36L1
UCEC
0.02
high
show
ENSG00000185650
ZFP36L1
ACC
0.016
high
show
ENSG00000185650
ZFP36L1
LGG
0.0017
high
show
ENSG00000185650
ZFP36L1
KIRP
0.00074
high
show
ENSG00000185650
ZFP36L1
KICH
0.024
low
show
ENSG00000185650
ZFP36L1
THYM
0.0031
high
show
ENSG00000185650
ZFP36L1
BRCA
0.012
low
show
ENSG00000185650
ZFP36L1
COAD
0.043
high
show
ENSG00000185650
ZFP36L1
UCS
0.00021
low
show
ENSG00000185650
ZFP36L1
OV
0.0022
high
show
ENSG00000185650
ZFP36L1
BLCA
0.038
high
show
ENSG00000185650
ZFP36L1
LAML
0.022
low
show
ENSG00000185650
ZFP36L1
GBM
0.025
high
show
ENSG00000185650
ZFP36L1
SKCM
0.013
low
show
ENSG00000185650
ZFP36L1
LIHC
0.014
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000185650
ZFP36L1
CHOL
Del
2.188176
0.330810
0.606633
0.583333
ENSG00000185650
ZFP36L1
LGG
Del
10.718496
0.108054
0.545094
0.231969
ENSG00000185650
ZFP36L1
SARC
Del
1.248834
0.137754
0.574422
0.307393
ENSG00000185650
ZFP36L1
GBM
Del
2.653875
0.073553
0.594992
0.298094
ENSG00000185650
ZFP36L1
LIHC
Del
3.466724
0.104168
0.518272
0.343243
ENSG00000185650
ZFP36L1
BLCA
Del
0.870089
0.079872
0.394233
0.330882
ENSG00000185650
ZFP36L1
BRCA
Del
9.212599
0.111673
0.432094
0.328704
ENSG00000185650
ZFP36L1
KIRC
Del
0.693182
0.024196
0.427303
0.429924
ENSG00000185650
ZFP36L1
OV
Del
4.613165
0.241773
0.538609
0.506045
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