Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerFlavivirusesSARS-COV-2DengueZika
Drug Drug
Main interacting RNAs N.A.
Moonlighting functions Metabolic enzyme
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000185624 Gene ID 5034 Accession 8548
Symbol P4HB Alias DSI;GIT;PDI;PHDB;PDIA1;PO4DB;PO4HB;PROHB;CLCRP1;ERBA2L;P4Hbeta Full Name prolyl 4-hydroxylase subunit beta
Status Confidence Length 17698 bases Strand Minus strand
Position 17 : 81843159 - 81860856 RNA binding domain N.A.
Summary This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
P4HB-234 ENST00000680083 2376 74aa ENSP00000505575
P4HB-256 ENST00000681030 2872 62aa ENSP00000505707
P4HB-220 ENST00000575069 2485 54aa ENSP00000459211
P4HB-242 ENST00000680416 3217 128aa ENSP00000506306
P4HB-215 ENST00000571507 1684 No protein -
P4HB-238 ENST00000680226 2451 521aa ENSP00000505635
P4HB-231 ENST00000679688 2429 126aa ENSP00000505272
P4HB-216 ENST00000571617 2302 466aa ENSP00000458300
P4HB-229 ENST00000679470 2780 No protein -
P4HB-263 ENST00000681515 2040 48aa ENSP00000505872
P4HB-259 ENST00000681161 2309 439aa ENSP00000505659
P4HB-252 ENST00000680884 2631 542aa ENSP00000505953
P4HB-267 ENST00000681693 2299 481aa ENSP00000505096
P4HB-201 ENST00000331483 2437 508aa ENSP00000327801
P4HB-254 ENST00000680914 2377 488aa ENSP00000505149
P4HB-245 ENST00000680593 2371 486aa ENSP00000505754
P4HB-261 ENST00000681420 2510 479aa ENSP00000505993
P4HB-219 ENST00000574914 2367 472aa ENSP00000460612
P4HB-241 ENST00000680400 2386 185aa ENSP00000505382
P4HB-260 ENST00000681259 3386 No protein -
P4HB-272 ENST00000681954 3878 No protein -
P4HB-269 ENST00000681835 4175 No protein -
P4HB-223 ENST00000576390 2288 463aa ENSP00000461718
P4HB-208 ENST00000473021 2010 No protein -
P4HB-209 ENST00000474712 3562 No protein -
P4HB-240 ENST00000680368 5270 No protein -
P4HB-235 ENST00000680105 2615 135aa ENSP00000506284
P4HB-233 ENST00000680076 2596 No protein -
P4HB-264 ENST00000681566 2609 270aa ENSP00000506218
P4HB-213 ENST00000484286 2691 No protein -
P4HB-270 ENST00000681872 3916 No protein -
P4HB-204 ENST00000466567 8201 No protein -
P4HB-202 ENST00000415593 2157 418aa ENSP00000388117
P4HB-226 ENST00000679396 2822 No protein -
P4HB-265 ENST00000681571 3438 No protein -
P4HB-232 ENST00000679889 2471 304aa ENSP00000506718
P4HB-246 ENST00000680719 2879 No protein -
P4HB-236 ENST00000680191 2487 533aa ENSP00000506544
P4HB-243 ENST00000680547 3508 No protein -
P4HB-248 ENST00000680799 3905 No protein -
P4HB-237 ENST00000680208 2907 No protein -
P4HB-227 ENST00000679439 2280 479aa ENSP00000505377
P4HB-207 ENST00000472244 2370 No protein -
P4HB-203 ENST00000439918 2299 464aa ENSP00000388374
P4HB-258 ENST00000681068 2977 No protein -
P4HB-250 ENST00000680846 2394 123aa ENSP00000506612
P4HB-257 ENST00000681031 2469 66aa ENSP00000505466
P4HB-211 ENST00000477607 2527 No protein -
P4HB-225 ENST00000679366 2711 270aa ENSP00000506375
P4HB-255 ENST00000681020 3432 557aa ENSP00000506014
P4HB-266 ENST00000681614 2721 No protein -
P4HB-262 ENST00000681485 2555 No protein -
P4HB-230 ENST00000679628 4068 No protein -
P4HB-210 ENST00000476482 1615 No protein -
P4HB-228 ENST00000679455 2346 54aa ENSP00000505971
P4HB-244 ENST00000680559 3654 No protein -
P4HB-239 ENST00000680259 3007 54aa ENSP00000504869
P4HB-253 ENST00000680909 2785 62aa ENSP00000505545
P4HB-268 ENST00000681760 2289 59aa ENSP00000506555
P4HB-271 ENST00000681933 2218 54aa ENSP00000504864
P4HB-214 ENST00000570907 2253 537aa ENSP00000461362
P4HB-247 ENST00000680732 1989 135aa ENSP00000505727
P4HB-249 ENST00000680838 2708 No protein -
P4HB-251 ENST00000680847 1881 222aa ENSP00000506451
P4HB-218 ENST00000574007 2196 No protein -
P4HB-217 ENST00000573778 1568 54aa ENSP00000460088
P4HB-212 ENST00000478034 811 No protein -
P4HB-222 ENST00000576380 943 54aa ENSP00000460285
P4HB-221 ENST00000576052 834 118aa ENSP00000461791
P4HB-206 ENST00000471535 969 No protein -
P4HB-224 ENST00000576541 1285 128aa ENSP00000460741
P4HB-205 ENST00000467086 1371 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000185624homo_sapiensENSP000002194066445.9048homo_sapiensENSP0000032780166.141747.4409
ENSG00000185624homo_sapiensENSP0000030546546.575328.0822homo_sapiensENSP0000032780153.543332.2835
ENSG00000185624homo_sapiensENSP0000030028949.70331.4851homo_sapiensENSP0000032780149.409531.2992
ENSG00000185624homo_sapiensENSP0000028303318.68489.70772homo_sapiensENSP0000032780135.236218.3071
ENSG00000185624homo_sapiensENSP0000039331633.928618.9286homo_sapiensENSP0000032780118.700810.4331
ENSG00000185624homo_sapiensENSP0000026639749.816830.0366homo_sapiensENSP0000032780126.771716.1417
ENSG00000185624homo_sapiensENSP0000029960835.682819.163homo_sapiensENSP0000032780131.889817.126
ENSG00000185624homo_sapiensENSP0000024602427.220614.6132homo_sapiensENSP0000032780118.700810.0394
ENSG00000185624homo_sapiensENSP0000036908134.027822.4537homo_sapiensENSP0000032780128.93719.0945
ENSG00000185624homo_sapiensENSP0000049912939.224825.4264homo_sapiensENSP0000032780149.803232.2835
ENSG00000185624homo_sapiensENSP0000026245543.349823.8916homo_sapiensENSP0000032780134.645719.0945
ENSG00000185624homo_sapiensENSP0000032331332.94820.2312homo_sapiensENSP0000032780133.661420.6693
ENSG00000185624homo_sapiensENSP0000027222733.863619.3182homo_sapiensENSP0000032780129.330716.7323

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000185624homo_sapiensENSP0000032780198.62298.0315nomascus_leucogenysENSNLEP0000003603496.718196.139
ENSG00000185624homo_sapiensENSP0000032780199.015798.622pan_paniscusENSPPAP0000002477298.050797.6608
ENSG00000185624homo_sapiensENSP0000032780199.606399.2126pongo_abeliiENSPPYP0000000981899.606399.2126
ENSG00000185624homo_sapiensENSP0000032780199.803199.6063pan_troglodytesENSPTRP0000001663699.803199.6063
ENSG00000185624homo_sapiensENSP0000032780199.803199.8031gorilla_gorillaENSGGOP0000002542599.803199.8031
ENSG00000185624homo_sapiensENSP0000032780195.078789.1732ornithorhynchus_anatinusENSOANP0000000977094.335988.4766
ENSG00000185624homo_sapiensENSP0000032780194.68587.9921sarcophilus_harrisiiENSSHAP0000003337194.313787.6471
ENSG00000185624homo_sapiensENSP0000032780175.984359.4488sarcophilus_harrisiiENSSHAP0000001612374.373858.1888
ENSG00000185624homo_sapiensENSP0000032780173.818960.0394notamacropus_eugeniiENSMEUP0000001055780.128265.1709
ENSG00000185624homo_sapiensENSP0000032780173.425267.9134notamacropus_eugeniiENSMEUP0000001528877.225771.4286
ENSG00000185624homo_sapiensENSP0000032780189.566987.2047dasypus_novemcinctusENSDNOP0000000910496.808594.2553
ENSG00000185624homo_sapiensENSP0000032780152.559151.1811erinaceus_europaeusENSEEUP000000021478986.6667
ENSG00000185624homo_sapiensENSP0000032780167.913463.7795echinops_telfairiENSETEP0000001548678.054373.3032
ENSG00000185624homo_sapiensENSP0000032780199.212697.4409callithrix_jacchusENSCJAP0000008787792.138990.4936
ENSG00000185624homo_sapiensENSP0000032780198.818998.2283cercocebus_atysENSCATP0000003146688.22587.6977
ENSG00000185624homo_sapiensENSP0000032780199.212698.0315macaca_mulattaENSMMUP0000006077898.823597.6471
ENSG00000185624homo_sapiensENSP0000032780199.212698.4252macaca_nemestrinaENSMNEP0000003768988.576487.8735
ENSG00000185624homo_sapiensENSP0000032780199.212698.622papio_anubisENSPANP0000001636498.823598.2353
ENSG00000185624homo_sapiensENSP0000032780189.960689.3701mandrillus_leucophaeusENSMLEP0000003622599.564398.9107
ENSG00000185624homo_sapiensENSP0000032780178.740276.5748tursiops_truncatusENSTTRP0000001164178.431476.2745
ENSG00000185624homo_sapiensENSP0000032780190.551286.6142vulpes_vulpesENSVVUP0000002733787.286583.4915
ENSG00000185624homo_sapiensENSP0000032780196.653593.8976mus_spretusMGP_SPRETEiJ_P003302096.463793.7132
ENSG00000185624homo_sapiensENSP0000032780193.897690.3543equus_asinusENSEASP0000505768788.007484.6863
ENSG00000185624homo_sapiensENSP0000032780197.834695.6693capra_hircusENSCHIP0000003264087.964686.0177
ENSG00000185624homo_sapiensENSP0000032780192.322887.9921loxodonta_africanaENSLAFP0000000117592.141587.8193
ENSG00000185624homo_sapiensENSP0000032780196.06392.5197panthera_leoENSPLOP0000002055595.686392.1569
ENSG00000185624homo_sapiensENSP0000032780196.850493.7008ailuropoda_melanoleucaENSAMEP0000001847496.470693.3333
ENSG00000185624homo_sapiensENSP0000032780197.834695.6693bos_indicus_hybridENSBIXP0000501045887.964686.0177
ENSG00000185624homo_sapiensENSP0000032780193.897690.3543equus_caballusENSECAP0000006537988.007484.6863
ENSG00000185624homo_sapiensENSP0000032780196.456793.5039canis_lupus_familiarisENSCAFP0084501275596.078493.1373
ENSG00000185624homo_sapiensENSP0000032780190.354386.811panthera_pardusENSPPRP0000001798595.426291.684
ENSG00000185624homo_sapiensENSP0000032780187.795386.0236marmota_marmota_marmotaENSMMMP0000000614187.622885.8546
ENSG00000185624homo_sapiensENSP0000032780197.047294.2913balaenoptera_musculusENSBMSP0001002360487.256684.7788
ENSG00000185624homo_sapiensENSP0000032780196.456794.0945cavia_porcellusENSCPOP0000001101696.267293.9096
ENSG00000185624homo_sapiensENSP0000032780196.06392.5197felis_catusENSFCAP0000002439295.686392.1569
ENSG00000185624homo_sapiensENSP0000032780197.244194.2913ursus_americanusENSUAMP0000002156696.862793.9216
ENSG00000185624homo_sapiensENSP0000032780194.881987.5984monodelphis_domesticaENSMODP0000000364594.509887.2549
ENSG00000185624homo_sapiensENSP0000032780127.755926.1811monodelphis_domesticaENSMODP0000005714589.808984.7134
ENSG00000185624homo_sapiensENSP0000032780127.165425.3937monodelphis_domesticaENSMODP0000005728384.662679.1411
ENSG00000185624homo_sapiensENSP0000032780177.362257.0866monodelphis_domesticaENSMODP0000001074176.310756.3107
ENSG00000185624homo_sapiensENSP0000032780110.82689.84252monodelphis_domesticaENSMODP0000005503884.615476.9231
ENSG00000185624homo_sapiensENSP0000032780197.834695.6693bison_bison_bisonENSBBBP0000000767197.45195.2941
ENSG00000185624homo_sapiensENSP0000032780197.047294.2913monodon_monocerosENSMMNP0001502648496.666793.9216
ENSG00000185624homo_sapiensENSP0000032780193.700887.9921sus_scrofaENSSSCP0000006871976.527371.865
ENSG00000185624homo_sapiensENSP0000032780197.440994.685microcebus_murinusENSMICP0000000104297.058894.3137
ENSG00000185624homo_sapiensENSP0000032780196.653594.0945octodon_degusENSODEP0000001291696.463793.9096
ENSG00000185624homo_sapiensENSP0000032780197.047293.8976jaculus_jaculusENSJJAP0000000975696.856693.7132
ENSG00000185624homo_sapiensENSP0000032780197.834695.6693ovis_aries_rambouilletENSOARP0002003279497.45195.2941
ENSG00000185624homo_sapiensENSP0000032780186.023681.2992ursus_maritimusENSUMAP0000002239092.194187.1308
ENSG00000185624homo_sapiensENSP0000032780197.244194.4882delphinapterus_leucasENSDLEP0000000429596.862794.1176
ENSG00000185624homo_sapiensENSP0000032780197.440993.8976physeter_catodonENSPCTP0000503056897.058893.5294
ENSG00000185624homo_sapiensENSP0000032780196.653593.8976mus_caroliMGP_CAROLIEiJ_P003156996.463793.7132
ENSG00000185624homo_sapiensENSP0000032780196.456793.8976mus_musculusENSMUSP0000002612296.267293.7132
ENSG00000185624homo_sapiensENSP0000032780190.354387.2047dipodomys_ordiiENSDORP0000001108894.639291.3402
ENSG00000185624homo_sapiensENSP0000032780132.283531.2992aotus_nancymaaeENSANAP0000001011395.906492.9825
ENSG00000185624homo_sapiensENSP0000032780188.18986.2205aotus_nancymaaeENSANAP0000002335584.688182.7977
ENSG00000185624homo_sapiensENSP0000032780188.582787.5984saimiri_boliviensis_boliviensisENSSBOP0000001148198.039296.9499
ENSG00000185624homo_sapiensENSP0000032780199.212698.622chlorocebus_sabaeusENSCSAP0000001581598.823598.2353
ENSG00000185624homo_sapiensENSP0000032780156.299251.9685tupaia_belangeriENSTBEP0000000179357.252.8
ENSG00000185624homo_sapiensENSP0000032780197.047293.8976mesocricetus_auratusENSMAUP0000002020696.856693.7132
ENSG00000185624homo_sapiensENSP0000032780192.716589.7638phocoena_sinusENSPSNP0000001913591.812988.8889
ENSG00000185624homo_sapiensENSP0000032780195.866190.748camelus_dromedariusENSCDRP0000501344382.542478.1356
ENSG00000185624homo_sapiensENSP0000032780197.244195.6693carlito_syrichtaENSTSYP0000001839496.862795.2941
ENSG00000185624homo_sapiensENSP0000032780124.409422.6378panthera_tigris_altaicaENSPTIP0000000188487.323980.9859
ENSG00000185624homo_sapiensENSP0000032780196.259893.8976rattus_norvegicusENSRNOP0000005184196.070793.7132
ENSG00000185624homo_sapiensENSP0000032780197.637895.2756prolemur_simusENSPSMP0000001910597.254994.902
ENSG00000185624homo_sapiensENSP0000032780196.850494.2913microtus_ochrogasterENSMOCP0000001748996.660194.1061
ENSG00000185624homo_sapiensENSP0000032780196.456794.0945peromyscus_maniculatus_bairdiiENSPEMP0000000422696.267293.9096
ENSG00000185624homo_sapiensENSP0000032780197.834695.6693bos_mutusENSBMUP0000003551287.964686.0177
ENSG00000185624homo_sapiensENSP0000032780196.456793.7008mus_spicilegusENSMSIP0000001636496.267293.5167
ENSG00000185624homo_sapiensENSP0000032780196.653593.3071cricetulus_griseus_chok1gshdENSCGRP0000101180896.463793.1238
ENSG00000185624homo_sapiensENSP0000032780194.881990.748pteropus_vampyrusENSPVAP0000001685394.695590.5697
ENSG00000185624homo_sapiensENSP0000032780197.047293.8976myotis_lucifugusENSMLUP0000001720996.101492.9825
ENSG00000185624homo_sapiensENSP0000032780175.196959.0551vombatus_ursinusENSVURP0001002289073.603157.8035
ENSG00000185624homo_sapiensENSP0000032780194.68588.189vombatus_ursinusENSVURP0001001127794.313787.8431
ENSG00000185624homo_sapiensENSP0000032780196.06392.126rhinolophus_ferrumequinumENSRFEP0001000798995.874391.945
ENSG00000185624homo_sapiensENSP0000032780195.866192.3228neovison_visonENSNVIP0000002089595.490291.9608
ENSG00000185624homo_sapiensENSP0000032780197.834695.4724bos_taurusENSBTAP0000000794387.964685.8407
ENSG00000185624homo_sapiensENSP0000032780188.385884.0551heterocephalus_glaber_femaleENSHGLP0000005269880.755476.7986
ENSG00000185624homo_sapiensENSP0000032780190.157588.7795rhinopithecus_bietiENSRBIP0000002620088.58887.234
ENSG00000185624homo_sapiensENSP0000032780196.259893.3071canis_lupus_dingoENSCAFP0002001216795.882492.9412
ENSG00000185624homo_sapiensENSP0000032780187.992186.0236sciurus_vulgarisENSSVLP0000502315383.551481.6822
ENSG00000185624homo_sapiensENSP0000032780165.157551.378phascolarctos_cinereusENSPCIP0000002569975.227359.3182
ENSG00000185624homo_sapiensENSP0000032780184.645778.1496phascolarctos_cinereusENSPCIP0000005173585.828379.2415
ENSG00000185624homo_sapiensENSP0000032780196.456790.9449procavia_capensisENSPCAP0000001222596.267290.7662
ENSG00000185624homo_sapiensENSP0000032780181.102475.7874nannospalax_galiliENSNGAP0000000773888.602182.7957
ENSG00000185624homo_sapiensENSP0000032780197.244194.4882nannospalax_galiliENSNGAP0000002380597.05394.3026
ENSG00000185624homo_sapiensENSP0000032780197.834695.6693bos_grunniensENSBGRP0000000615087.964686.0177
ENSG00000185624homo_sapiensENSP0000032780196.850494.8819chinchilla_lanigeraENSCLAP0000001042396.660194.6955
ENSG00000185624homo_sapiensENSP0000032780197.440995.2756cervus_hanglu_yarkandensisENSCHYP0000003613997.058894.902
ENSG00000185624homo_sapiensENSP0000032780195.866190.3543catagonus_wagneriENSCWAP0000001040895.866190.3543
ENSG00000185624homo_sapiensENSP0000032780196.850495.2756ictidomys_tridecemlineatusENSSTOP0000002186696.660195.0884
ENSG00000185624homo_sapiensENSP0000032780196.850493.3071otolemur_garnettiiENSOGAP0000000212196.470692.9412
ENSG00000185624homo_sapiensENSP0000032780199.212698.2283cebus_imitatorENSCCAP0000003687098.823597.8431
ENSG00000185624homo_sapiensENSP0000032780197.047295.2756urocitellus_parryiiENSUPAP0001000039784.417882.8767
ENSG00000185624homo_sapiensENSP0000032780197.834695.6693moschus_moschiferusENSMMSP0000003160997.45195.2941
ENSG00000185624homo_sapiensENSP0000032780199.015798.2283rhinopithecus_roxellanaENSRROP0000000755498.627497.8431
ENSG00000185624homo_sapiensENSP0000032780196.259894.2913mus_pahariMGP_PahariEiJ_P003828296.070794.1061
ENSG00000185624homo_sapiensENSP0000032780197.440995.4724propithecus_coquereliENSPCOP0000001411597.058895.098
ENSG00000185624homo_sapiensENSP0000032780130.118117.5197caenorhabditis_elegansM04D5.1.146.084326.8072
ENSG00000185624homo_sapiensENSP0000032780162.007941.1417caenorhabditis_elegansC14B1.1.164.948543.0928
ENSG00000185624homo_sapiensENSP0000032780173.62255.315caenorhabditis_elegansC07A12.4.175.862156.998
ENSG00000185624homo_sapiensENSP0000032780130.31518.5039caenorhabditis_elegansZK973.11.134.451921.0291
ENSG00000185624homo_sapiensENSP0000032780147.637830.9055caenorhabditis_elegansH06O01.1.149.590232.1721
ENSG00000185624homo_sapiensENSP0000032780171.456752.9528drosophila_melanogasterFBpp031222473.185554.2339
ENSG00000185624homo_sapiensENSP0000032780133.661418.3071drosophila_melanogasterFBpp007521239.767421.6279
ENSG00000185624homo_sapiensENSP0000032780147.047230.315drosophila_melanogasterFBpp008716448.875331.4928
ENSG00000185624homo_sapiensENSP0000032780168.503950ciona_intestinalisENSCINP0000000634269.184950.497
ENSG00000185624homo_sapiensENSP0000032780145.078730.7087ciona_intestinalisENSCINP0000000577346.926231.9672
ENSG00000185624homo_sapiensENSP0000032780132.480326.378petromyzon_marinusENSPMAP0000001022185.492269.4301
ENSG00000185624homo_sapiensENSP0000032780178.740262.2047eptatretus_burgeriENSEBUP0000002692975.614459.7354
ENSG00000185624homo_sapiensENSP0000032780182.480369.0945callorhinchus_miliiENSCMIP0000004875377.592665
ENSG00000185624homo_sapiensENSP0000032780185.433177.3622latimeria_chalumnaeENSLACP0000000412085.940677.8218
ENSG00000185624homo_sapiensENSP0000032780183.858373.2283lepisosteus_oculatusENSLOCP0000001713481.765871.4012
ENSG00000185624homo_sapiensENSP0000032780182.086670.8661clupea_harengusENSCHAP0000000795182.086670.8661
ENSG00000185624homo_sapiensENSP0000032780185.039472.4409danio_rerioENSDARP0000013865784.872372.2986
ENSG00000185624homo_sapiensENSP0000032780181.889871.063carassius_auratusENSCARP0000005080375.362365.3986
ENSG00000185624homo_sapiensENSP0000032780183.661472.4409carassius_auratusENSCARP0000000358280.645269.8292
ENSG00000185624homo_sapiensENSP0000032780183.858372.6378astyanax_mexicanusENSAMXP0000003886683.693572.4951
ENSG00000185624homo_sapiensENSP0000032780184.055173.4252ictalurus_punctatusENSIPUP0000003328983.725573.1373
ENSG00000185624homo_sapiensENSP0000032780183.070972.2441esox_luciusENSELUP0000003126477.573567.4632
ENSG00000185624homo_sapiensENSP0000032780183.661470.8661electrophorus_electricusENSEEEP0000001200378.849766.7904
ENSG00000185624homo_sapiensENSP0000032780181.889871.2598oncorhynchus_kisutchENSOKIP0000500517677.323467.2862
ENSG00000185624homo_sapiensENSP0000032780182.283571.063oncorhynchus_kisutchENSOKIP0000507372977.695267.1004
ENSG00000185624homo_sapiensENSP0000032780182.283571.6535oncorhynchus_mykissENSOMYP0000012421581.481570.9552
ENSG00000185624homo_sapiensENSP0000032780181.889870.6693oncorhynchus_mykissENSOMYP0000001813481.568670.3922
ENSG00000185624homo_sapiensENSP0000032780120.078716.7323oncorhynchus_mykissENSOMYP0000002019866.666755.5556
ENSG00000185624homo_sapiensENSP0000032780183.267771.4567salmo_salarENSSSAP0000004508779.511368.2331
ENSG00000185624homo_sapiensENSP0000032780181.692970.4724salmo_salarENSSSAP0000004539479.654568.714
ENSG00000185624homo_sapiensENSP0000032780181.299270.2756salmo_truttaENSSTUP0000009861776.908866.4804
ENSG00000185624homo_sapiensENSP0000032780183.661472.0472salmo_truttaENSSTUP0000004941683.007871.4844
ENSG00000185624homo_sapiensENSP0000032780183.464669.2913gadus_morhuaENSGMOP0000003599775.579362.7451
ENSG00000185624homo_sapiensENSP0000032780184.448872.2441fundulus_heteroclitusENSFHEP0000002251784.282972.1022
ENSG00000185624homo_sapiensENSP0000032780184.448872.2441poecilia_reticulataENSPREP0000000473684.282972.1022
ENSG00000185624homo_sapiensENSP0000032780184.448872.0472xiphophorus_maculatusENSXMAP0000003091584.282971.9057
ENSG00000185624homo_sapiensENSP0000032780185.236271.8504oryzias_latipesENSORLP0000000211184.735871.4286
ENSG00000185624homo_sapiensENSP0000032780181.102469.8819cyclopterus_lumpusENSCLMP0000500855978.178467.3624
ENSG00000185624homo_sapiensENSP0000032780183.464671.2598oreochromis_niloticusENSONIP0000000416661.538552.5399
ENSG00000185624homo_sapiensENSP0000032780117.12613.3858haplochromis_burtoniENSHBUP000000332085845.3333
ENSG00000185624homo_sapiensENSP0000032780183.858372.2441astatotilapia_callipteraENSACLP0000001497883.203171.6797
ENSG00000185624homo_sapiensENSP0000032780182.283571.063sparus_aurataENSSAUP0001000239280.69569.6911
ENSG00000185624homo_sapiensENSP0000032780184.25273.0315lates_calcariferENSLCAP0001002226883.106872.0388
ENSG00000185624homo_sapiensENSP0000032780185.826876.5748xenopus_tropicalisENSXETP0000001192083.365274.3786
ENSG00000185624homo_sapiensENSP0000032780189.370181.4961chrysemys_picta_belliiENSCPBP0000001554490.258482.3062
ENSG00000185624homo_sapiensENSP0000032780190.354383.8583sphenodon_punctatusENSSPUP0000001420789.473783.0409
ENSG00000185624homo_sapiensENSP0000032780184.055174.4094laticauda_laticaudataENSLLTP0000001127988.958378.75
ENSG00000185624homo_sapiensENSP0000032780187.992178.5433notechis_scutatusENSNSUP0000001435686.96577.6265
ENSG00000185624homo_sapiensENSP0000032780187.992178.5433pseudonaja_textilisENSPTXP0000000446786.96577.6265
ENSG00000185624homo_sapiensENSP0000032780186.417378.7402anas_platyrhynchos_platyrhynchosENSAPLP0000001409493.603485.2878
ENSG00000185624homo_sapiensENSP0000032780184.448875.9843gallus_gallusENSGALP0001004486582.026873.805
ENSG00000185624homo_sapiensENSP0000032780172.834666.5354meleagris_gallopavoENSMGAP0000001729893.908685.7868
ENSG00000185624homo_sapiensENSP0000032780183.464674.4094serinus_canariaENSSCAP0000001527488.702979.0795
ENSG00000185624homo_sapiensENSP0000032780188.18978.937parus_majorENSPMJP000000204967062.6562
ENSG00000185624homo_sapiensENSP0000032780188.976480.7087anolis_carolinensisENSACAP0000001042488.45480.2348
ENSG00000185624homo_sapiensENSP0000032780116.732313.5827neolamprologus_brichardiENSNBRP0000000299966.929154.3307
ENSG00000185624homo_sapiensENSP0000032780173.818963.189neolamprologus_brichardiENSNBRP0000002292377.319666.1856
ENSG00000185624homo_sapiensENSP0000032780187.795378.3465naja_najaENSNNAP0000001874286.770477.4319
ENSG00000185624homo_sapiensENSP0000032780189.173282.2835podarcis_muralisENSPMRP0000000855687.790781.0078
ENSG00000185624homo_sapiensENSP0000032780182.086672.8346geospiza_fortisENSGFOP0000001258287.789577.8947
ENSG00000185624homo_sapiensENSP0000032780190.354381.8898taeniopygia_guttataENSTGUP0000002441289.299680.9339
ENSG00000185624homo_sapiensENSP0000032780185.039475.9843erpetoichthys_calabaricusENSECRP0000003408885.714376.5873
ENSG00000185624homo_sapiensENSP0000032780183.661471.2598kryptolebias_marmoratusENSKMAP0000001579183.007870.7031
ENSG00000185624homo_sapiensENSP0000032780189.763880.1181salvator_merianaeENSSMRP0000003046888.71679.1829
ENSG00000185624homo_sapiensENSP0000032780184.055171.8504oryzias_javanicusENSOJAP0000001502781.644469.7897
ENSG00000185624homo_sapiensENSP0000032780183.464671.8504amphilophus_citrinellusENSACIP0000002619982.974671.4286
ENSG00000185624homo_sapiensENSP0000032780182.480371.6535dicentrarchus_labraxENSDLAP0000502661378.759468.4211
ENSG00000185624homo_sapiensENSP0000032780183.858372.8346amphiprion_perculaENSAPEP0000001980783.203172.2656
ENSG00000185624homo_sapiensENSP0000032780183.070970.6693oryzias_sinensisENSOSIP0000004496779.924267.9924
ENSG00000185624homo_sapiensENSP0000032780177.952871.063pelodiscus_sinensisENSPSIP000000200218880.2222
ENSG00000185624homo_sapiensENSP0000032780191.732382.874gopherus_evgoodeiENSGEVP0000502118989.101380.4971
ENSG00000185624homo_sapiensENSP0000032780191.535482.874chelonoidis_abingdoniiENSCABP0000001288889.251480.8061
ENSG00000185624homo_sapiensENSP0000032780183.858373.4252seriola_dumeriliENSSDUP0000000532782.398572.147
ENSG00000185624homo_sapiensENSP0000032780181.889869.0945cottoperca_gobioENSCGOP0000001584666.24255.8917
ENSG00000185624homo_sapiensENSP0000032780175.590668.3071struthio_camelus_australisENSSCUP0000000858288.275979.7701
ENSG00000185624homo_sapiensENSP0000032780192.12683.8583anser_brachyrhynchusENSABRP0000001254590.173482.0809
ENSG00000185624homo_sapiensENSP0000032780182.677269.2913gasterosteus_aculeatusENSGACP0000002403980.614267.5624
ENSG00000185624homo_sapiensENSP0000032780181.889868.8976cynoglossus_semilaevisENSCSEP0000002415081.40968.4931
ENSG00000185624homo_sapiensENSP0000032780183.858372.2441poecilia_formosaENSPFOP0000001701583.529471.9608
ENSG00000185624homo_sapiensENSP0000032780181.889871.4567myripristis_murdjanENSMMDP0000501778978.048868.1051
ENSG00000185624homo_sapiensENSP0000032780181.692969.685sander_luciopercaENSSLUP0000002842374.506363.5548
ENSG00000185624homo_sapiensENSP0000032780191.338682.874strigops_habroptilaENSSHBP0000501799390.448382.0663
ENSG00000185624homo_sapiensENSP0000032780182.480371.6535amphiprion_ocellarisENSAOCP0000001043282.156971.3726
ENSG00000185624homo_sapiensENSP0000032780186.417378.937terrapene_carolina_triunguisENSTMTP0000001657475.820469.2573
ENSG00000185624homo_sapiensENSP0000032780183.267772.2441hucho_huchoENSHHUP0000005699782.295771.4008
ENSG00000185624homo_sapiensENSP0000032780183.267771.8504hucho_huchoENSHHUP0000004542380.879569.7897
ENSG00000185624homo_sapiensENSP0000032780182.677272.2441betta_splendensENSBSLP0000003224378.947468.985
ENSG00000185624homo_sapiensENSP0000032780184.842572.6378pygocentrus_nattereriENSPNAP0000003677484.344472.2113
ENSG00000185624homo_sapiensENSP0000032780182.086671.063anabas_testudineusENSATEP0000006439076.654466.3603
ENSG00000185624homo_sapiensENSP0000032780168.700850ciona_savignyiENSCSAVP0000001906270.221351.1066
ENSG00000185624homo_sapiensENSP0000032780120.472412.5984ciona_savignyiENSCSAVP0000001588651.231531.5271
ENSG00000185624homo_sapiensENSP0000032780146.259827.7559saccharomyces_cerevisiaeYCL043C45.019227.0115
ENSG00000185624homo_sapiensENSP0000032780142.322824.0157saccharomyces_cerevisiaeYDR518W41.586123.5977
ENSG00000185624homo_sapiensENSP0000032780183.858373.4252seriola_lalandi_dorsalisENSSLDP0000000188982.398572.147
ENSG00000185624homo_sapiensENSP0000032780183.070970.8661labrus_bergyltaENSLBEP0000001683882.421970.3125
ENSG00000185624homo_sapiensENSP0000032780183.858372.2441pundamilia_nyerereiENSPNYP0000000376883.203171.6797
ENSG00000185624homo_sapiensENSP0000032780182.283570.0787mastacembelus_armatusENSMAMP0000003963780.851168.8588
ENSG00000185624homo_sapiensENSP0000032780183.464671.6535stegastes_partitusENSSPAP0000002193182.974671.2329
ENSG00000185624homo_sapiensENSP0000032780181.889871.4567oncorhynchus_tshawytschaENSOTSP0000505925977.323467.4721
ENSG00000185624homo_sapiensENSP0000032780178.149666.9291oncorhynchus_tshawytschaENSOTSP0000509064174.344663.6704
ENSG00000185624homo_sapiensENSP0000032780177.755966.7323oncorhynchus_tshawytschaENSOTSP0000507531775.525864.8184
ENSG00000185624homo_sapiensENSP0000032780181.889871.4567oncorhynchus_tshawytschaENSOTSP0000505671577.323467.4721
ENSG00000185624homo_sapiensENSP0000032780184.645772.6378acanthochromis_polyacanthusENSAPOP0000000008683.820771.9298
ENSG00000185624homo_sapiensENSP0000032780191.535483.6614aquila_chrysaetos_chrysaetosENSACCP0002000112190.820383.0078
ENSG00000185624homo_sapiensENSP0000032780184.055171.063nothobranchius_furzeriENSNFUP0001504329574.003562.565
ENSG00000185624homo_sapiensENSP0000032780184.645772.0472cyprinodon_variegatusENSCVAP0000000604283.984471.4844
ENSG00000185624homo_sapiensENSP0000032780183.267772.2441denticeps_clupeoidesENSDCDP0000001852978.333367.963
ENSG00000185624homo_sapiensENSP0000032780181.889870.2756larimichthys_croceaENSLCRP0000505990780.464269.0522
ENSG00000185624homo_sapiensENSP0000032780182.87470.8661takifugu_rubripesENSTRUP0000008293674.119763.3803
ENSG00000185624homo_sapiensENSP0000032780188.582779.7244ficedula_albicollisENSFALP0000003411881.227473.1047
ENSG00000185624homo_sapiensENSP0000032780183.661471.8504hippocampus_comesENSHCOP0000001116681.573970.0576
ENSG00000185624homo_sapiensENSP0000032780182.480371.8504cyprinus_carpio_carpioENSCCRP0000012301180.422370.0576
ENSG00000185624homo_sapiensENSP0000032780181.692970.6693cyprinus_carpio_carpioENSCCRP0000011934779.807769.0385
ENSG00000185624homo_sapiensENSP0000032780191.929183.4646coturnix_japonicaENSCJPP0000502727490.679682.3301
ENSG00000185624homo_sapiensENSP0000032780184.055172.2441poecilia_latipinnaENSPLAP0000001145683.8972.1022
ENSG00000185624homo_sapiensENSP0000032780183.858373.0315sinocyclocheilus_grahamiENSSGRP0000008096783.693572.888
ENSG00000185624homo_sapiensENSP0000032780181.102470.2756sinocyclocheilus_grahamiENSSGRP0000003377979.383468.7861
ENSG00000185624homo_sapiensENSP0000032780183.858372.2441maylandia_zebraENSMZEP0000501608583.203171.6797
ENSG00000185624homo_sapiensENSP0000032780184.055172.0472tetraodon_nigroviridisENSTNIP0000001714783.235971.345
ENSG00000185624homo_sapiensENSP0000032780184.645774.0157paramormyrops_kingsleyaeENSPKIP0000002222877.477567.7477
ENSG00000185624homo_sapiensENSP0000032780184.448873.0315scleropages_formosusENSSFOP0001505877080.79169.8682
ENSG00000185624homo_sapiensENSP0000032780186.023675.5906leptobrachium_leishanenseENSLLEP0000003831986.363675.8893
ENSG00000185624homo_sapiensENSP0000032780182.480370.8661scophthalmus_maximusENSSMAP0000003727370.184360.3015
ENSG00000185624homo_sapiensENSP0000032780185.039472.4409oryzias_melastigmaENSOMEP0000000574084.540172.0157

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003756enables protein disulfide isomerase activity3EXP,IBA,IDAHomo_sapiens(9606)Function
GO:0003779enables actin binding1IPIHomo_sapiens(9606)Function
GO:0004656contributes_to procollagen-proline 4-dioxygenase activity1IDAHomo_sapiens(9606)Function
GO:0005178enables integrin binding1IPIHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005576located_in extracellular region1NASHomo_sapiens(9606)Component
GO:0005783is_active_in endoplasmic reticulum2IBA,IDAHomo_sapiens(9606)Component
GO:0005788located_in endoplasmic reticulum lumen1TASHomo_sapiens(9606)Component
GO:0005793located_in endoplasmic reticulum-Golgi intermediate compartment1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0005856located_in cytoskeleton1IDAHomo_sapiens(9606)Component
GO:0005925located_in focal adhesion1HDAHomo_sapiens(9606)Component
GO:0006457involved_in protein folding1IBAHomo_sapiens(9606)Process
GO:0006888involved_in endoplasmic reticulum to Golgi vesicle-mediated transport1IEAHomo_sapiens(9606)Process
GO:0009897is_active_in external side of plasma membrane2IBA,IDAHomo_sapiens(9606)Component
GO:0015035enables protein-disulfide reductase activity2EXP,IDAHomo_sapiens(9606)Function
GO:0016222part_of procollagen-proline 4-dioxygenase complex1IDAHomo_sapiens(9606)Component
GO:0016972enables thiol oxidase activity1IDAHomo_sapiens(9606)Function
GO:0018401acts_upstream_of_or_within peptidyl-proline hydroxylation to 4-hydroxy-L-proline1IDAHomo_sapiens(9606)Process
GO:0019899enables enzyme binding1IEAHomo_sapiens(9606)Function
GO:0030027located_in lamellipodium1IDAHomo_sapiens(9606)Component
GO:0030070involved_in insulin processing1TASHomo_sapiens(9606)Process
GO:0032991part_of protein-containing complex1IDAHomo_sapiens(9606)Component
GO:0034663part_of endoplasmic reticulum chaperone complex1IEAHomo_sapiens(9606)Component
GO:0034975involved_in protein folding in endoplasmic reticulum1IDAHomo_sapiens(9606)Process
GO:0034976involved_in response to endoplasmic reticulum stress2IBA,IMPHomo_sapiens(9606)Process
GO:0035722involved_in interleukin-12-mediated signaling pathway1TASHomo_sapiens(9606)Process
GO:0038155involved_in interleukin-23-mediated signaling pathway1TASHomo_sapiens(9606)Process
GO:0042470located_in melanosome1IEAHomo_sapiens(9606)Component
GO:0045785involved_in positive regulation of cell adhesion1IMPHomo_sapiens(9606)Process
GO:0046598involved_in positive regulation of viral entry into host cell1IMPHomo_sapiens(9606)Process
GO:0046982enables protein heterodimerization activity1IDAHomo_sapiens(9606)Function
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component
GO:0071456involved_in cellular response to hypoxia1IMPHomo_sapiens(9606)Process
GO:0098761involved_in cellular response to interleukin-71IEAHomo_sapiens(9606)Process
GO:1900026involved_in positive regulation of substrate adhesion-dependent cell spreading1IMPHomo_sapiens(9606)Process
GO:1902175involved_in regulation of oxidative stress-induced intrinsic apoptotic signaling pathway1IMPHomo_sapiens(9606)Process

Expression