Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerFlavivirusesDengue
Drug Drug
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000181222 Gene ID 5430 Accession 9187
Symbol POLR2A Alias RPB1;RPO2;POLR2;POLRA;RPBh1;RPOL2;NEDHIB;RpIILS;hsRPB1;hRPB220 Full Name RNA polymerase II subunit A
Status Confidence Length 29814 bases Strand Plus strand
Position 17 : 7484366 - 7514179 RNA binding domain RNA_pol_Rpb1_4 , RNA_pol_Rpb1_1 , RNA_pol_Rpb1_5 , RNA_pol_Rpb1_2 , RNA_pol_Rpb1_3 , RNA_pol_Rpb1_R , RNA_pol_Rpb1_6 , RNA_pol_Rpb1_7
Summary This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000502190 RNA_pol_Rpb1_7 PF04990 9.9e-54 1
ENSP00000502190 RNA_pol_Rpb1_6 PF04992 1.1e-67 2
ENSP00000502190 RNA_pol_Rpb1_1 PF04997 2.7e-108 3
ENSP00000502190 RNA_pol_Rpb1_3 PF04983 4.2e-49 4
ENSP00000502190 RNA_pol_Rpb1_4 PF05000 1.8e-37 5
ENSP00000502190 RNA_pol_Rpb1_2 PF00623 5.7e-74 6
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 7
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 8
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 9
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 10
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 11
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 12
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 13
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 14
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 15
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 16
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 17
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 18
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 19
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 20
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 21
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 22
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 23
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 24
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 25
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 26
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 27
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 28
ENSP00000502190 RNA_pol_Rpb1_R PF05001 6.4e-27 29
ENSP00000502190 RNA_pol_Rpb1_5 PF04998 3.2e-100 30

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
36172261 Identification of the key immune-related genes in aneurysmal subarachnoid hemorrhage. Xing Wang 2022-01-01 Frontiers in molecular neuroscience
28975155 Genome-wide scan in Hispanics highlights candidate loci for brain white matter hyperintensities. Ashley Beecham 2017-10-01 Neurology. Genetics
36357561 Immune and spermatogenesis-related loci are involved in the development of extreme patterns of male infertility. Miriam Cerván-Martín 2022-11-10 Communications biology
31948478 CHROMATIX: computing the functional landscape of many-body chromatin interactions in transcriptionally active loci from deconvolved single cells. Alan Perez-Rathke 2020-01-16 Genome biology
37248388 Learning consistent subcellular landmarks to quantify changes in multiplexed protein maps. Hannah Spitzer 2023-07-01 Nature methods
26071189 Regulation and function of the human HSP90AA1 gene. D Abbey Zuehlke 2015-10-01 Gene
28240266 Genome-wide identification of splicing QTLs in the human brain and their enrichment among schizophrenia-associated loci. Atsushi Takata 2017-02-27 Nature communications
37169843 A sense-antisense RNA interaction promotes breast cancer metastasis via regulation of NQO1 expression. Bruce Culbertson 2023-05-01 Nature cancer
31092820 Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus. A Christopher Odhams 2019-05-15 Nature communications
36768794 A Comprehensive Investigation of Genomic Variants in Prostate Cancer Reveals 30 Putative Regulatory Variants. Mahdieh Labani 2023-01-27 International journal of molecular sciences
27503294 Epigenetic Variability across Human Populations: A Focus on DNA Methylation Profiles of the KRTCAP3, MAD1L1 and BRSK2 Genes. Cristina Giuliani 2016-09-19 Genome biology and evolution

Transcripts

Name Transcript ID bp Protein Translation ID
POLR2A-210 ENST00000674977 6312 1970aa ENSP00000502190
POLR2A-209 ENST00000617998 6751 No protein -
POLR2A-201 ENST00000572844 2083 No protein -
POLR2A-208 ENST00000576952 532 No protein -
POLR2A-204 ENST00000575547 702 No protein -
POLR2A-205 ENST00000576114 245 No protein -
POLR2A-207 ENST00000576718 548 No protein -
POLR2A-203 ENST00000574158 461 No protein -
POLR2A-202 ENST00000573603 648 No protein -
POLR2A-206 ENST00000576553 602 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000181222homo_sapiensENSP0000036144655.395736.4748homo_sapiensENSP0000050219039.086325.736
ENSG00000181222homo_sapiensENSP0000026385739.069824.3605homo_sapiensENSP0000050219034.111721.269
ENSG00000181222homo_sapiensENSP0000049484099.949299.9492homo_sapiensENSP0000050219099.949299.9492

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000181222homo_sapiensENSP0000050219091.624491.2183nomascus_leucogenysENSNLEP0000001155592.091891.6837
ENSG00000181222homo_sapiensENSP0000050219093.604192.7919pan_paniscusENSPPAP0000004234891.513690.7196
ENSG00000181222homo_sapiensENSP0000050219098.527998.4264pongo_abeliiENSPPYP0000000891198.527998.4264
ENSG00000181222homo_sapiensENSP0000050219091.624491.2183pan_troglodytesENSPTRP0000004246892.091891.6837
ENSG00000181222homo_sapiensENSP0000050219091.218390.6091gorilla_gorillaENSGGOP0000001445091.683791.0714
ENSG00000181222homo_sapiensENSP0000050219028.121828.0203ornithorhynchus_anatinusENSOANP0000000523699.283298.9247
ENSG00000181222homo_sapiensENSP0000050219099.847799.4924sarcophilus_harrisiiENSSHAP0000000324099.847799.4924
ENSG00000181222homo_sapiensENSP0000050219074.771674.264notamacropus_eugeniiENSMEUP0000000789687.783187.1871
ENSG00000181222homo_sapiensENSP0000050219097.461997.0558dasypus_novemcinctusENSDNOP0000001278198.663998.2528
ENSG00000181222homo_sapiensENSP0000050219078.477278.2741erinaceus_europaeusENSEEUP0000000104194.44194.1967
ENSG00000181222homo_sapiensENSP000005021908079.0355echinops_telfairiENSETEP0000000207383.254182.2504
ENSG00000181222homo_sapiensENSP0000050219098.527998.4264callithrix_jacchusENSCJAP0000002801398.527998.4264
ENSG00000181222homo_sapiensENSP0000050219098.527998.3756cercocebus_atysENSCATP0000000430698.527998.3756
ENSG00000181222homo_sapiensENSP0000050219028.629428.3756macaca_fascicularisENSMFAP0000001035399.646698.7633
ENSG00000181222homo_sapiensENSP0000050219098.527998.3756macaca_mulattaENSMMUP0000006030798.527998.3756
ENSG00000181222homo_sapiensENSP0000050219099.644799.5431macaca_nemestrinaENSMNEP0000003452099.291999.1907
ENSG00000181222homo_sapiensENSP0000050219028.629428.3756papio_anubisENSPANP0000003238799.646698.7633
ENSG00000181222homo_sapiensENSP0000050219095.888395.1269mandrillus_leucophaeusENSMLEP0000001271797.572396.7975
ENSG00000181222homo_sapiensENSP0000050219098.73198.3756tursiops_truncatusENSTTRP0000001353099.285398.928
ENSG00000181222homo_sapiensENSP0000050219097.106697.0051vulpes_vulpesENSVVUP0000003910998.506798.4037
ENSG00000181222homo_sapiensENSP0000050219098.477298.3756mus_spretusMGP_SPRETEiJ_P002899398.477298.3756
ENSG00000181222homo_sapiensENSP0000050219099.898599.8985equus_asinusENSEASP0000502825199.898599.8985
ENSG00000181222homo_sapiensENSP0000050219098.527998.3756capra_hircusENSCHIP0000003374498.527998.3756
ENSG00000181222homo_sapiensENSP0000050219099.898599.8985loxodonta_africanaENSLAFP0000001947799.898599.8985
ENSG00000181222homo_sapiensENSP0000050219086.700584.6193panthera_leoENSPLOP0000002930682.792180.8047
ENSG00000181222homo_sapiensENSP0000050219099.949299.797ailuropoda_melanoleucaENSAMEP0000001721999.949299.797
ENSG00000181222homo_sapiensENSP0000050219099.949299.8985bos_indicus_hybridENSBIXP0000504031797.523597.474
ENSG00000181222homo_sapiensENSP0000050219091.979791.5228equus_caballusENSECAP0000005770993.114192.6516
ENSG00000181222homo_sapiensENSP0000050219099.949299.8985canis_lupus_familiarisENSCAFP0084503129099.949299.8985
ENSG00000181222homo_sapiensENSP0000050219028.578728.4264panthera_pardusENSPPRP0000000475799.294598.7654
ENSG00000181222homo_sapiensENSP0000050219098.527998.4264marmota_marmota_marmotaENSMMMP0000002234698.527998.4264
ENSG00000181222homo_sapiensENSP0000050219098.527998.3756balaenoptera_musculusENSBMSP0001001910198.527998.3756
ENSG00000181222homo_sapiensENSP0000050219092.385891.4213cavia_porcellusENSCPOP0000001334799.290898.2542
ENSG00000181222homo_sapiensENSP0000050219086.497585.533felis_catusENSFCAP0000003890874.93474.0985
ENSG00000181222homo_sapiensENSP0000050219090.964590ursus_americanusENSUAMP0000001938997.550496.5161
ENSG00000181222homo_sapiensENSP0000050219099.847799.4924monodelphis_domesticaENSMODP0000000869199.847799.4924
ENSG00000181222homo_sapiensENSP0000050219098.883298.6294bison_bison_bisonENSBBBP0000000696698.284698.0323
ENSG00000181222homo_sapiensENSP0000050219094.720894.1117monodon_monocerosENSMMNP0001502339494.48193.8734
ENSG00000181222homo_sapiensENSP0000050219099.847799.8477sus_scrofaENSSSCP0000002432699.949299.9492
ENSG00000181222homo_sapiensENSP0000050219099.289398.8832microcebus_murinusENSMICP0000003336699.03898.6329
ENSG00000181222homo_sapiensENSP0000050219095.482295.1269octodon_degusENSODEP0000002414998.533398.1666
ENSG00000181222homo_sapiensENSP0000050219099.949299.8477jaculus_jaculusENSJJAP0000000910099.949299.8477
ENSG00000181222homo_sapiensENSP0000050219098.527998.3756ovis_aries_rambouilletENSOARP0002001783398.527998.3756
ENSG00000181222homo_sapiensENSP0000050219091.06690.7614ursus_maritimusENSUMAP0000002250399.280698.9485
ENSG00000181222homo_sapiensENSP0000050219080.20380.1523ochotona_princepsENSOPRP0000001382499.936899.8735
ENSG00000181222homo_sapiensENSP0000050219098.527998.3756delphinapterus_leucasENSDLEP0000002942298.527998.3756
ENSG00000181222homo_sapiensENSP0000050219098.984898.8832physeter_catodonENSPCTP0000502106699.948799.8462
ENSG00000181222homo_sapiensENSP0000050219098.477298.3756mus_caroliMGP_CAROLIEiJ_P002761298.477298.3756
ENSG00000181222homo_sapiensENSP0000050219098.477298.3756mus_musculusENSMUSP0000005077198.477298.3756
ENSG00000181222homo_sapiensENSP0000050219098.527998.4264dipodomys_ordiiENSDORP0000002609798.527998.4264
ENSG00000181222homo_sapiensENSP0000050219098.527998.3249mustela_putorius_furoENSMPUP0000000957298.527998.3249
ENSG00000181222homo_sapiensENSP0000050219098.527998.4264aotus_nancymaaeENSANAP0000000445998.527998.4264
ENSG00000181222homo_sapiensENSP0000050219098.527998.4264saimiri_boliviensis_boliviensisENSSBOP0000000030198.527998.4264
ENSG00000181222homo_sapiensENSP0000050219051.675151.4213vicugna_pacosENSVPAP0000000822771.438671.0877
ENSG00000181222homo_sapiensENSP0000050219094.111792.8934chlorocebus_sabaeusENSCSAP0000000772494.063992.8463
ENSG00000181222homo_sapiensENSP0000050219058.274158.2234tupaia_belangeriENSTBEP0000001154458.36358.3121
ENSG00000181222homo_sapiensENSP0000050219049.949249.8477mesocricetus_auratusENSMAUP0000002410599.69699.4934
ENSG00000181222homo_sapiensENSP0000050219098.527998.3756phocoena_sinusENSPSNP0000001585998.527998.3756
ENSG00000181222homo_sapiensENSP0000050219098.121898.0203camelus_dromedariusENSCDRP0000501079698.471798.3698
ENSG00000181222homo_sapiensENSP0000050219097.969597.9695carlito_syrichtaENSTSYP0000001573999.896599.8965
ENSG00000181222homo_sapiensENSP0000050219027.309627.2081panthera_tigris_altaicaENSPTIP0000000262998.354797.989
ENSG00000181222homo_sapiensENSP0000050219099.949299.8477rattus_norvegicusENSRNOP0000006149299.949299.8477
ENSG00000181222homo_sapiensENSP0000050219028.578728.4264prolemur_simusENSPSMP0000002779999.294598.7654
ENSG00000181222homo_sapiensENSP0000050219096.59996.3452microtus_ochrogasterENSMOCP0000002070196.403296.1499
ENSG00000181222homo_sapiensENSP0000050219081.218380.6599sorex_araneusENSSARP0000000537095.522494.8657
ENSG00000181222homo_sapiensENSP0000050219098.527998.4264peromyscus_maniculatus_bairdiiENSPEMP0000001210498.527998.4264
ENSG00000181222homo_sapiensENSP0000050219087.66586.9543bos_mutusENSBMUP0000000819594.114493.3515
ENSG00000181222homo_sapiensENSP0000050219098.477298.3756mus_spicilegusENSMSIP0000003056398.477298.3756
ENSG00000181222homo_sapiensENSP0000050219095.685395.533cricetulus_griseus_chok1gshdENSCGRP0000100306698.023997.8679
ENSG00000181222homo_sapiensENSP0000050219099.695499.6954pteropus_vampyrusENSPVAP0000000479699.898399.8983
ENSG00000181222homo_sapiensENSP0000050219099.695499.5431myotis_lucifugusENSMLUP0000000829999.594399.4422
ENSG00000181222homo_sapiensENSP0000050219096.497595.5838vombatus_ursinusENSVURP0001000379599.685498.7415
ENSG00000181222homo_sapiensENSP0000050219098.527998.4264rhinolophus_ferrumequinumENSRFEP0001001976998.527998.4264
ENSG00000181222homo_sapiensENSP0000050219098.527998.3249neovison_visonENSNVIP0000000418698.527998.3249
ENSG00000181222homo_sapiensENSP0000050219098.527998.3756bos_taurusENSBTAP0000006584898.527998.3756
ENSG00000181222homo_sapiensENSP0000050219093.147292.335rhinopithecus_bietiENSRBIP0000000056394.538993.7146
ENSG00000181222homo_sapiensENSP0000050219099.340199.0355canis_lupus_dingoENSCAFP0002001029899.643699.3381
ENSG00000181222homo_sapiensENSP0000050219098.527998.4264sciurus_vulgarisENSSVLP0000502173098.527998.4264
ENSG00000181222homo_sapiensENSP0000050219095.989895.0761phascolarctos_cinereusENSPCIP0000003930996.038695.1244
ENSG00000181222homo_sapiensENSP0000050219091.573691.5228procavia_capensisENSPCAP0000000656091.759991.7091
ENSG00000181222homo_sapiensENSP0000050219098.527998.4264nannospalax_galiliENSNGAP0000000275998.527998.4264
ENSG00000181222homo_sapiensENSP0000050219091.167590.5584bos_grunniensENSBGRP0000002938198.464997.807
ENSG00000181222homo_sapiensENSP0000050219094.619394.0102chinchilla_lanigeraENSCLAP0000001777594.619394.0102
ENSG00000181222homo_sapiensENSP0000050219098.527998.4264cervus_hanglu_yarkandensisENSCHYP0000001388998.527998.4264
ENSG00000181222homo_sapiensENSP0000050219098.527998.4264catagonus_wagneriENSCWAP0000000485298.527998.4264
ENSG00000181222homo_sapiensENSP0000050219098.527998.4264ictidomys_tridecemlineatusENSSTOP0000003108998.527998.4264
ENSG00000181222homo_sapiensENSP0000050219099.847799.797otolemur_garnettiiENSOGAP0000002030299.847799.797
ENSG00000181222homo_sapiensENSP0000050219098.527998.4264cebus_imitatorENSCCAP0000000648798.527998.4264
ENSG00000181222homo_sapiensENSP0000050219098.527998.4264urocitellus_parryiiENSUPAP0001001917198.527998.4264
ENSG00000181222homo_sapiensENSP0000050219028.629428.5279moschus_moschiferusENSMMSP0000001565598.947498.5965
ENSG00000181222homo_sapiensENSP0000050219099.593999.5431rhinopithecus_roxellanaENSRROP0000001035898.49498.4438
ENSG00000181222homo_sapiensENSP0000050219098.883298.4772mus_pahariMGP_PahariEiJ_P003436098.833198.4272
ENSG00000181222homo_sapiensENSP0000050219099.492499.4416propithecus_coquereliENSPCOP0000002596499.0999.0394
ENSG00000181222homo_sapiensENSP0000050219080.659967.4619caenorhabditis_elegansF36A4.7.185.614271.6056
ENSG00000181222homo_sapiensENSP0000050219083.350371.269drosophila_melanogasterFBpp007338787.016474.4038
ENSG00000181222homo_sapiensENSP0000050219081.06670.203ciona_intestinalisENSCINP0000001616688.037576.2404
ENSG00000181222homo_sapiensENSP0000050219094.365587.2081eptatretus_burgeriENSEBUP0000002267394.461487.2967
ENSG00000181222homo_sapiensENSP000005021908.274117.96954callorhinchus_miliiENSCMIP0000000414789.560486.2637
ENSG00000181222homo_sapiensENSP0000050219091.218388.2234latimeria_chalumnaeENSLACP0000001371693.593890.5208
ENSG00000181222homo_sapiensENSP0000050219094.974691.8274lepisosteus_oculatusENSLOCP0000001710595.507992.343
ENSG00000181222homo_sapiensENSP0000050219096.852893.2487clupea_harengusENSCHAP0000004161396.951293.3435
ENSG00000181222homo_sapiensENSP0000050219097.918894.9746danio_rerioENSDARP0000013503898.167995.2163
ENSG00000181222homo_sapiensENSP0000050219097.86894.7716carassius_auratusENSCARP0000003690498.117195.0127
ENSG00000181222homo_sapiensENSP0000050219097.817394.9239carassius_auratusENSCARP0000003332098.066295.1654
ENSG00000181222homo_sapiensENSP0000050219098.223495.1777astyanax_mexicanusENSAMXP0000003905298.423295.3713
ENSG00000181222homo_sapiensENSP0000050219097.969594.6701ictalurus_punctatusENSIPUP0000000378298.168994.8627
ENSG00000181222homo_sapiensENSP0000050219097.411293.8579esox_luciusENSELUP0000004590197.361793.8102
ENSG00000181222homo_sapiensENSP0000050219098.020395.1269electrophorus_electricusENSEEEP0000003532098.219795.3204
ENSG00000181222homo_sapiensENSP0000050219097.563593.7563oncorhynchus_kisutchENSOKIP0000506716497.712293.8993
ENSG00000181222homo_sapiensENSP0000050219088.883284.1117oncorhynchus_kisutchENSOKIP0000502387888.523883.7715
ENSG00000181222homo_sapiensENSP0000050219097.563593.7563oncorhynchus_mykissENSOMYP0000001773497.712293.8993
ENSG00000181222homo_sapiensENSP0000050219097.66593.6548oncorhynchus_mykissENSOMYP0000010802997.66593.6548
ENSG00000181222homo_sapiensENSP0000050219091.319886.8528salmo_salarENSSSAP0000011814593.260888.6988
ENSG00000181222homo_sapiensENSP0000050219086.548282.1827salmo_salarENSSSAP0000000732888.204983.7558
ENSG00000181222homo_sapiensENSP0000050219097.512793.6041salmo_truttaENSSTUP0000010628397.661493.7468
ENSG00000181222homo_sapiensENSP0000050219097.66593.6548salmo_truttaENSSTUP0000007026297.66593.6548
ENSG00000181222homo_sapiensENSP0000050219097.411294.0102gadus_morhuaENSGMOP0000000827598.008294.5863
ENSG00000181222homo_sapiensENSP0000050219095.076191.1675fundulus_heteroclitusENSFHEP0000002179497.755793.737
ENSG00000181222homo_sapiensENSP0000050219097.918894.9746poecilia_reticulataENSPREP0000001950898.11895.1679
ENSG00000181222homo_sapiensENSP0000050219097.918894.9746xiphophorus_maculatusENSXMAP0000001573798.11895.1679
ENSG00000181222homo_sapiensENSP0000050219097.918894.7716oryzias_latipesENSORLP0000003812198.11894.9644
ENSG00000181222homo_sapiensENSP0000050219096.700593.198cyclopterus_lumpusENSCLMP0000503085596.897393.3876
ENSG00000181222homo_sapiensENSP0000050219095.025490.6599oreochromis_niloticusENSONIP0000007070796.994892.5389
ENSG00000181222homo_sapiensENSP0000050219094.517890.3046haplochromis_burtoniENSHBUP0000001683497.691593.3368
ENSG00000181222homo_sapiensENSP0000050219097.208194.0102astatotilapia_callipteraENSACLP0000000991797.405994.2014
ENSG00000181222homo_sapiensENSP0000050219092.436589.3401sparus_aurataENSSAUP0001002980392.624689.5219
ENSG00000181222homo_sapiensENSP0000050219098.121895.0761lates_calcariferENSLCAP0001001614698.321595.2696
ENSG00000181222homo_sapiensENSP0000050219099.086396.9036xenopus_tropicalisENSXETP0000008159799.18797.002
ENSG00000181222homo_sapiensENSP0000050219095.177793.9086chrysemys_picta_belliiENSCPBP0000001772197.758196.4546
ENSG00000181222homo_sapiensENSP0000050219020.761420.5076sphenodon_punctatusENSSPUP0000002314696.462395.283
ENSG00000181222homo_sapiensENSP0000050219026.395926.1421sphenodon_punctatusENSSPUP0000002315798.859397.9087
ENSG00000181222homo_sapiensENSP0000050219098.477297.3604laticauda_laticaudataENSLLTP0000002124298.878797.7574
ENSG00000181222homo_sapiensENSP0000050219080.609176.3959notechis_scutatusENSNSUP0000002365182.837878.5081
ENSG00000181222homo_sapiensENSP0000050219098.223497.1574pseudonaja_textilisENSPTXP0000002059098.623997.5535
ENSG00000181222homo_sapiensENSP0000050219064.010263.2995gallus_gallusENSGALP0001000290499.213298.1117
ENSG00000181222homo_sapiensENSP0000050219099.390998.3756anolis_carolinensisENSACAP0000001448799.441398.4256
ENSG00000181222homo_sapiensENSP0000050219095.431592.335neolamprologus_brichardiENSNBRP0000000257897.510494.3465
ENSG00000181222homo_sapiensENSP0000050219099.289398.2234podarcis_muralisENSPMRP0000001774599.339898.2732
ENSG00000181222homo_sapiensENSP0000050219097.86896.599taeniopygia_guttataENSTGUP0000002727298.871897.5897
ENSG00000181222homo_sapiensENSP0000050219097.86896.3959taeniopygia_guttataENSTGUP0000002445698.871897.3846
ENSG00000181222homo_sapiensENSP0000050219098.223495.4822erpetoichthys_calabaricusENSECRP0000001565498.323295.5793
ENSG00000181222homo_sapiensENSP0000050219075.888372.9442kryptolebias_marmoratusENSKMAP0000002204584.130680.8666
ENSG00000181222homo_sapiensENSP0000050219099.289398.3756salvator_merianaeENSSMRP0000000388599.339898.4256
ENSG00000181222homo_sapiensENSP0000050219097.918894.8223oryzias_javanicusENSOJAP0000003098198.11895.0153
ENSG00000181222homo_sapiensENSP0000050219096.192993.2995amphilophus_citrinellusENSACIP0000002065098.288495.3319
ENSG00000181222homo_sapiensENSP0000050219096.80293.7563dicentrarchus_labraxENSDLAP0000501901098.096795.0103
ENSG00000181222homo_sapiensENSP0000050219098.020394.9746amphiprion_perculaENSAPEP0000001777698.219795.1679
ENSG00000181222homo_sapiensENSP0000050219093.19890oryzias_sinensisENSOSIP0000000170194.541791.2976
ENSG00000181222homo_sapiensENSP0000050219081.675180.6599pelodiscus_sinensisENSPSIP0000001588998.4797.246
ENSG00000181222homo_sapiensENSP0000050219089.137187.3604chelonoidis_abingdoniiENSCABP0000001896795.799293.8898
ENSG00000181222homo_sapiensENSP0000050219097.66594.5178seriola_dumeriliENSSDUP0000002841197.863794.7101
ENSG00000181222homo_sapiensENSP0000050219095.329991.4213cottoperca_gobioENSCGOP0000001496896.754292.7872
ENSG00000181222homo_sapiensENSP0000050219063.705658.6294struthio_camelus_australisENSSCUP0000000022069.76164.2023
ENSG00000181222homo_sapiensENSP0000050219080.20376.5482gasterosteus_aculeatusENSGACP0000002559995.583891.2281
ENSG00000181222homo_sapiensENSP0000050219096.59993.2995cynoglossus_semilaevisENSCSEP0000000408196.844893.5369
ENSG00000181222homo_sapiensENSP0000050219094.974692.0812poecilia_formosaENSPFOP0000000810698.112295.1232
ENSG00000181222homo_sapiensENSP0000050219098.020394.8731myripristis_murdjanENSMMDP0000505127098.219795.0661
ENSG00000181222homo_sapiensENSP0000050219098.020394.6193sander_luciopercaENSSLUP0000003827598.219794.8118
ENSG00000181222homo_sapiensENSP0000050219097.66596.0406strigops_habroptilaENSSHBP0000501470899.328997.6768
ENSG00000181222homo_sapiensENSP0000050219092.182788.1218amphiprion_ocellarisENSAOCP0000000127591.902887.8542
ENSG00000181222homo_sapiensENSP0000050219084.771683.0457terrapene_carolina_triunguisENSTMTP0000002840088.782686.975
ENSG00000181222homo_sapiensENSP0000050219083.756380.2538hucho_huchoENSHHUP0000000023897.460193.3845
ENSG00000181222homo_sapiensENSP0000050219082.639679.1371hucho_huchoENSHHUP0000006146395.483991.437
ENSG00000181222homo_sapiensENSP0000050219098.071194.8223betta_splendensENSBSLP0000001848298.270695.0153
ENSG00000181222homo_sapiensENSP0000050219098.071195.0254pygocentrus_nattereriENSPNAP0000000482198.270695.2187
ENSG00000181222homo_sapiensENSP0000050219098.071194.8731anabas_testudineusENSATEP0000002855998.270695.0661
ENSG00000181222homo_sapiensENSP0000050219088.832577.3096ciona_savignyiENSCSAVP0000001421188.787477.2704
ENSG00000181222homo_sapiensENSP0000050219063.908649.2386saccharomyces_cerevisiaeYDL140C72.648655.9723
ENSG00000181222homo_sapiensENSP0000050219097.66594.5178seriola_lalandi_dorsalisENSSLDP0000002658897.863794.7101
ENSG00000181222homo_sapiensENSP0000050219098.020394.6701labrus_bergyltaENSLBEP0000003704798.269794.9109
ENSG00000181222homo_sapiensENSP0000050219097.208194.0609pundamilia_nyerereiENSPNYP0000002967397.405994.2523
ENSG00000181222homo_sapiensENSP0000050219096.903693.6041mastacembelus_armatusENSMAMP0000000514396.854493.5566
ENSG00000181222homo_sapiensENSP0000050219092.233589.1371stegastes_partitusENSSPAP0000002222092.941289.821
ENSG00000181222homo_sapiensENSP0000050219088.121883.7056oncorhynchus_tshawytschaENSOTSP0000501384292.242387.6196
ENSG00000181222homo_sapiensENSP0000050219092.690488.6802acanthochromis_polyacanthusENSAPOP0000000491692.596488.5903
ENSG00000181222homo_sapiensENSP0000050219085.025482.6396aquila_chrysaetos_chrysaetosENSACCP0002002462995.116492.4475
ENSG00000181222homo_sapiensENSP0000050219096.80293.7563nothobranchius_furzeriENSNFUP0001500359496.851293.804
ENSG00000181222homo_sapiensENSP0000050219097.614294.7716cyprinodon_variegatusENSCVAP0000000390197.812894.9644
ENSG00000181222homo_sapiensENSP0000050219093.553388.8832denticeps_clupeoidesENSDCDP0000003327791.64687.0711
ENSG00000181222homo_sapiensENSP0000050219097.360494.3147larimichthys_croceaENSLCRP0000501270198.258295.1844
ENSG00000181222homo_sapiensENSP0000050219097.66594.4162takifugu_rubripesENSTRUP0000008721097.913594.6565
ENSG00000181222homo_sapiensENSP0000050219096.649793.3503hippocampus_comesENSHCOP0000002339296.846493.5402
ENSG00000181222homo_sapiensENSP0000050219097.918894.6701cyprinus_carpio_carpioENSCCRP0000010353598.167994.9109
ENSG00000181222homo_sapiensENSP0000050219097.817394.8731cyprinus_carpio_carpioENSCCRP0000017561098.066295.1145
ENSG00000181222homo_sapiensENSP0000050219094.974692.0812poecilia_latipinnaENSPLAP0000000538498.112295.1232
ENSG00000181222homo_sapiensENSP0000050219097.918894.6193sinocyclocheilus_grahamiENSSGRP0000004920098.167994.8601
ENSG00000181222homo_sapiensENSP0000050219097.817394.5685sinocyclocheilus_grahamiENSSGRP0000002735298.066294.8092
ENSG00000181222homo_sapiensENSP0000050219097.208194.0102maylandia_zebraENSMZEP0000502873397.405994.2014
ENSG00000181222homo_sapiensENSP0000050219084.720881.6751tetraodon_nigroviridisENSTNIP0000001303497.374693.874
ENSG00000181222homo_sapiensENSP0000050219077.614274.6193paramormyrops_kingsleyaeENSPKIP0000002129282.60479.4165
ENSG00000181222homo_sapiensENSP0000050219098.172695.0254scleropages_formosusENSSFOP0001503662398.272495.1219
ENSG00000181222homo_sapiensENSP0000050219099.035597.1574leptobrachium_leishanenseENSLLEP0000001306799.136297.2561
ENSG00000181222homo_sapiensENSP0000050219097.918894.467scophthalmus_maximusENSSMAP0000001492498.11894.6592
ENSG00000181222homo_sapiensENSP0000050219075.939173.198oryzias_melastigmaENSOMEP0000002787591.948488.6294

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0001055contributes_to RNA polymerase II activity1IBAHomo_sapiens(9606)Function
GO:0001172involved_in RNA-templated transcription1IEAHomo_sapiens(9606)Process
GO:0003677enables DNA binding1NASHomo_sapiens(9606)Function
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003899enables DNA-directed 5-3 RNA polymerase activity1NASHomo_sapiens(9606)Function
GO:0003968enables RNA-dependent RNA polymerase activity1IEAHomo_sapiens(9606)Function
GO:0005515contributes_to protein binding2IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus2IDA,NASHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1TASHomo_sapiens(9606)Component
GO:0005665part_of RNA polymerase II, core complex2IBA,IDAHomo_sapiens(9606)Component
GO:0005694located_in chromosome1IEAHomo_sapiens(9606)Component
GO:0005730NOT located_in nucleolus1IDAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IEAHomo_sapiens(9606)Component
GO:0006353involved_in DNA-templated transcription termination1IMPHomo_sapiens(9606)Process
GO:0006355involved_in regulation of DNA-templated transcription1NASHomo_sapiens(9606)Process
GO:0006366involved_in transcription by RNA polymerase II2IDA,NASHomo_sapiens(9606)Process
GO:0019900enables kinase binding1IPIHomo_sapiens(9606)Function
GO:0031625enables ubiquitin protein ligase binding1IPIHomo_sapiens(9606)Function
GO:0033120involved_in positive regulation of RNA splicing1IDAHomo_sapiens(9606)Process
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function
GO:1990841enables promoter-specific chromatin binding1IDAHomo_sapiens(9606)Function

Expression