RBP Type	Canonical_RBPs
Diseases	Cancer
Drug	N.A.
Main interacting RNAs	diverse
Moonlighting functions	N.A.
Localizations	Nucleoli
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000181026	Gene ID	64782	Accession	25722
Symbol	AEN	Alias	ISG20L1;pp12744	Full Name	apoptosis enhancing nuclease
Status	Confidence	Length	10942 bases	Strand	Plus strand
Position	15 : 88621340 - 88632281	RNA binding domain	RNase_T
Summary	Enables exonuclease activity. Involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and response to ionizing radiation. Located in nuclear membrane; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000331944	RNase_T	PF00929	4.5e-16	1
ENSP00000453631	RNase_T	PF00929	1e-07	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
35883600	Exonucleases: Degrading DNA to Deal with Genome Damage, Cell Death, Inflammation and Cancer.	Joan Manils	2022-07-09	Cells

Name	Transcript ID	bp	Protein	Translation ID
AEN-201	ENST00000332810	3072	325aa	ENSP00000331944
AEN-202	ENST00000557787	1242	No protein	-
AEN-205	ENST00000559528	895	179aa	ENSP00000453631
AEN-206	ENST00000560174	461	No protein	-
AEN-204	ENST00000558327	883	No protein	-
AEN-203	ENST00000557927	5039	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
14642	Alzheimer Disease	2.4138175E-005	17998437
96922	Sleep	9E-6	27126917

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000181026	homo_sapiens	ENSP00000361010	32.4645	19.6682	homo_sapiens	ENSP00000331944	42.1538	25.5385
ENSG00000181026	homo_sapiens	ENSP00000306565	63.5359	53.5912	homo_sapiens	ENSP00000331944	35.3846	29.8462
ENSG00000181026	homo_sapiens	ENSP00000261377	14.3411	8.65633	homo_sapiens	ENSP00000331944	34.1538	20.6154
ENSG00000181026	homo_sapiens	ENSP00000170168	9.41851	5.81491	homo_sapiens	ENSP00000331944	35.3846	21.8462
ENSG00000181026	homo_sapiens	ENSP00000357202	50.1416	37.6771	homo_sapiens	ENSP00000331944	54.4615	40.9231

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000181026	homo_sapiens	ENSP00000331944	98.4615	97.8462	nomascus_leucogenys	ENSNLEP00000028329	98.4615	97.8462
ENSG00000181026	homo_sapiens	ENSP00000331944	99.6923	99.3846	pan_paniscus	ENSPPAP00000033468	99.6923	99.3846
ENSG00000181026	homo_sapiens	ENSP00000331944	98.1538	97.5385	pongo_abelii	ENSPPYP00000007664	98.1538	97.5385
ENSG00000181026	homo_sapiens	ENSP00000331944	99.6923	99.3846	pan_troglodytes	ENSPTRP00000051293	99.6923	99.3846
ENSG00000181026	homo_sapiens	ENSP00000331944	99.6923	99.3846	gorilla_gorilla	ENSGGOP00000019404	99.6923	99.3846
ENSG00000181026	homo_sapiens	ENSP00000331944	62.1538	52	ornithorhynchus_anatinus	ENSOANP00000046621	57.0621	47.7401
ENSG00000181026	homo_sapiens	ENSP00000331944	68.3077	57.2308	sarcophilus_harrisii	ENSSHAP00000032130	62.0112	51.9553
ENSG00000181026	homo_sapiens	ENSP00000331944	65.2308	55.3846	notamacropus_eugenii	ENSMEUP00000004848	68.3871	58.0645
ENSG00000181026	homo_sapiens	ENSP00000331944	82.7692	79.0769	dasypus_novemcinctus	ENSDNOP00000001429	88.1967	84.2623
ENSG00000181026	homo_sapiens	ENSP00000331944	48.3077	42.7692	dasypus_novemcinctus	ENSDNOP00000022827	75.1196	66.5072
ENSG00000181026	homo_sapiens	ENSP00000331944	71.6923	63.6923	erinaceus_europaeus	ENSEEUP00000006388	84.4203	75
ENSG00000181026	homo_sapiens	ENSP00000331944	74.7692	68.3077	echinops_telfairi	ENSETEP00000005008	83.2192	76.0274
ENSG00000181026	homo_sapiens	ENSP00000331944	96	92	callithrix_jacchus	ENSCJAP00000023813	96	92
ENSG00000181026	homo_sapiens	ENSP00000331944	96.3077	94.4615	cercocebus_atys	ENSCATP00000021726	96.3077	94.4615
ENSG00000181026	homo_sapiens	ENSP00000331944	96.9231	94.7692	macaca_fascicularis	ENSMFAP00000003384	70.7865	69.2135
ENSG00000181026	homo_sapiens	ENSP00000331944	96.9231	94.7692	macaca_mulatta	ENSMMUP00000064241	96.9231	94.7692
ENSG00000181026	homo_sapiens	ENSP00000331944	96.9231	95.0769	macaca_nemestrina	ENSMNEP00000033783	96.9231	95.0769
ENSG00000181026	homo_sapiens	ENSP00000331944	96.6154	95.0769	papio_anubis	ENSPANP00000059814	70.5618	69.4382
ENSG00000181026	homo_sapiens	ENSP00000331944	96.6154	94.7692	mandrillus_leucophaeus	ENSMLEP00000017296	96.6154	94.7692
ENSG00000181026	homo_sapiens	ENSP00000331944	81.2308	75.6923	tursiops_truncatus	ENSTTRP00000013906	83.5443	77.8481
ENSG00000181026	homo_sapiens	ENSP00000331944	88	83.0769	vulpes_vulpes	ENSVVUP00000016371	82.1839	77.5862
ENSG00000181026	homo_sapiens	ENSP00000331944	61.5385	58.1538	mus_spretus	MGP_SPRETEiJ_P0083537	78.125	73.8281
ENSG00000181026	homo_sapiens	ENSP00000331944	86.1538	80.3077	equus_asinus	ENSEASP00005022480	80.6916	75.2161
ENSG00000181026	homo_sapiens	ENSP00000331944	84.6154	78.1538	capra_hircus	ENSCHIP00000000991	84.0979	77.6758
ENSG00000181026	homo_sapiens	ENSP00000331944	80	76.3077	loxodonta_africana	ENSLAFP00000012711	85.2459	81.3115
ENSG00000181026	homo_sapiens	ENSP00000331944	84.6154	80	panthera_leo	ENSPLOP00000030077	84.6154	80
ENSG00000181026	homo_sapiens	ENSP00000331944	84.9231	80.6154	ailuropoda_melanoleuca	ENSAMEP00000043584	85.1852	80.8642
ENSG00000181026	homo_sapiens	ENSP00000331944	83.6923	79.6923	bos_indicus_hybrid	ENSBIXP00005039032	83.1804	79.2049
ENSG00000181026	homo_sapiens	ENSP00000331944	40	37.5385	oryctolagus_cuniculus	ENSOCUP00000024849	81.761	76.7296
ENSG00000181026	homo_sapiens	ENSP00000331944	86.4615	80.6154	equus_caballus	ENSECAP00000041946	69.9005	65.1741
ENSG00000181026	homo_sapiens	ENSP00000331944	88	83.0769	canis_lupus_familiaris	ENSCAFP00845005192	54.1667	51.1364
ENSG00000181026	homo_sapiens	ENSP00000331944	84.6154	80	panthera_pardus	ENSPPRP00000003457	83.5866	79.0274
ENSG00000181026	homo_sapiens	ENSP00000331944	87.0769	82.7692	marmota_marmota_marmota	ENSMMMP00000023049	86.8098	82.5153
ENSG00000181026	homo_sapiens	ENSP00000331944	84.9231	79.0769	balaenoptera_musculus	ENSBMSP00010005444	65.2482	60.7565
ENSG00000181026	homo_sapiens	ENSP00000331944	83.6923	77.5385	cavia_porcellus	ENSCPOP00000015351	85	78.75
ENSG00000181026	homo_sapiens	ENSP00000331944	85.2308	80.6154	felis_catus	ENSFCAP00000019215	67.7262	64.0587
ENSG00000181026	homo_sapiens	ENSP00000331944	49.5385	47.6923	ursus_americanus	ENSUAMP00000024386	92	88.5714
ENSG00000181026	homo_sapiens	ENSP00000331944	69.2308	59.3846	monodelphis_domestica	ENSMODP00000048307	67.3653	57.7844
ENSG00000181026	homo_sapiens	ENSP00000331944	84	79.6923	bison_bison_bison	ENSBBBP00000008029	84	79.6923
ENSG00000181026	homo_sapiens	ENSP00000331944	84.3077	78.4615	monodon_monoceros	ENSMMNP00015011816	86.7089	80.6962
ENSG00000181026	homo_sapiens	ENSP00000331944	88.6154	82.7692	sus_scrofa	ENSSSCP00000005483	88.6154	82.7692
ENSG00000181026	homo_sapiens	ENSP00000331944	89.5385	85.5385	microcebus_murinus	ENSMICP00000022179	90.3727	86.3354
ENSG00000181026	homo_sapiens	ENSP00000331944	47.3846	44.3077	octodon_degus	ENSODEP00000020710	92.2156	86.2275
ENSG00000181026	homo_sapiens	ENSP00000331944	48.3077	45.2308	jaculus_jaculus	ENSJJAP00000022634	90.2299	84.4828
ENSG00000181026	homo_sapiens	ENSP00000331944	84.6154	78.4615	ovis_aries_rambouillet	ENSOARP00020010004	65.9472	61.1511
ENSG00000181026	homo_sapiens	ENSP00000331944	23.0769	21.2308	ursus_maritimus	ENSUMAP00000008185	90.3614	83.1325
ENSG00000181026	homo_sapiens	ENSP00000331944	18.4615	17.2308	delphinapterus_leucas	ENSDLEP00000002291	68.9655	64.3678
ENSG00000181026	homo_sapiens	ENSP00000331944	84.3077	78.7692	delphinapterus_leucas	ENSDLEP00000008284	86.7089	81.0127
ENSG00000181026	homo_sapiens	ENSP00000331944	21.2308	19.0769	physeter_catodon	ENSPCTP00005003746	71.134	63.9175
ENSG00000181026	homo_sapiens	ENSP00000331944	84.9231	79.3846	physeter_catodon	ENSPCTP00005014192	87.3418	81.6456
ENSG00000181026	homo_sapiens	ENSP00000331944	78.7692	72.6154	mus_caroli	MGP_CAROLIEiJ_P0080185	76.1905	70.2381
ENSG00000181026	homo_sapiens	ENSP00000331944	78.7692	72.3077	mus_musculus	ENSMUSP00000103048	76.1905	69.9405
ENSG00000181026	homo_sapiens	ENSP00000331944	76	66.1538	dipodomys_ordii	ENSDORP00000014630	81.25	70.7237
ENSG00000181026	homo_sapiens	ENSP00000331944	86.7692	80.3077	mustela_putorius_furo	ENSMPUP00000015713	74.4063	68.8654
ENSG00000181026	homo_sapiens	ENSP00000331944	97.2308	93.5385	aotus_nancymaae	ENSANAP00000017655	83.1579	80
ENSG00000181026	homo_sapiens	ENSP00000331944	94.4615	90.7692	saimiri_boliviensis_boliviensis	ENSSBOP00000009989	94.7531	91.0494
ENSG00000181026	homo_sapiens	ENSP00000331944	95.6923	94.4615	chlorocebus_sabaeus	ENSCSAP00000013233	95.6923	94.4615
ENSG00000181026	homo_sapiens	ENSP00000331944	82.7692	77.8462	tupaia_belangeri	ENSTBEP00000014103	84.326	79.3103
ENSG00000181026	homo_sapiens	ENSP00000331944	81.2308	75.6923	mesocricetus_auratus	ENSMAUP00000000603	81.7337	76.161
ENSG00000181026	homo_sapiens	ENSP00000331944	84	78.4615	phocoena_sinus	ENSPSNP00000004675	86.3924	80.6962
ENSG00000181026	homo_sapiens	ENSP00000331944	19.0769	17.2308	phocoena_sinus	ENSPSNP00000016808	70.4545	63.6364
ENSG00000181026	homo_sapiens	ENSP00000331944	88	81.2308	camelus_dromedarius	ENSCDRP00005029878	77.5068	71.5447
ENSG00000181026	homo_sapiens	ENSP00000331944	89.2308	85.2308	carlito_syrichta	ENSTSYP00000011389	89.2308	85.2308
ENSG00000181026	homo_sapiens	ENSP00000331944	70.1538	64.9231	panthera_tigris_altaica	ENSPTIP00000022010	65.896	60.9827
ENSG00000181026	homo_sapiens	ENSP00000331944	80.3077	74.1538	rattus_norvegicus	ENSRNOP00000062841	78.6145	72.5904
ENSG00000181026	homo_sapiens	ENSP00000331944	89.8462	85.2308	prolemur_simus	ENSPSMP00000007466	89.8462	85.2308
ENSG00000181026	homo_sapiens	ENSP00000331944	79.6923	74.7692	microtus_ochrogaster	ENSMOCP00000011479	79.4479	74.5399
ENSG00000181026	homo_sapiens	ENSP00000331944	83.0769	75.6923	peromyscus_maniculatus_bairdii	ENSPEMP00000023398	83.0769	75.6923
ENSG00000181026	homo_sapiens	ENSP00000331944	76.9231	71.3846	bos_mutus	ENSBMUP00000003849	71.6332	66.4756
ENSG00000181026	homo_sapiens	ENSP00000331944	78.7692	72.3077	mus_spicilegus	ENSMSIP00000021888	76.1905	69.9405
ENSG00000181026	homo_sapiens	ENSP00000331944	80.3077	74.7692	cricetulus_griseus_chok1gshd	ENSCGRP00001023277	81.5625	75.9375
ENSG00000181026	homo_sapiens	ENSP00000331944	84.6154	78.7692	pteropus_vampyrus	ENSPVAP00000006784	84.0979	78.2875
ENSG00000181026	homo_sapiens	ENSP00000331944	67.3846	62.7692	myotis_lucifugus	ENSMLUP00000019405	89.3878	83.2653
ENSG00000181026	homo_sapiens	ENSP00000331944	68.9231	59.0769	vombatus_ursinus	ENSVURP00010009644	61.8785	53.0387
ENSG00000181026	homo_sapiens	ENSP00000331944	87.0769	80.3077	rhinolophus_ferrumequinum	ENSRFEP00010013157	75.8713	69.9732
ENSG00000181026	homo_sapiens	ENSP00000331944	85.8462	78.7692	neovison_vison	ENSNVIP00000023210	73.6148	67.5462
ENSG00000181026	homo_sapiens	ENSP00000331944	83.6923	79.6923	bos_taurus	ENSBTAP00000023454	83.1804	79.2049
ENSG00000181026	homo_sapiens	ENSP00000331944	79.6923	72.3077	heterocephalus_glaber_female	ENSHGLP00000041955	84.6405	76.7974
ENSG00000181026	homo_sapiens	ENSP00000331944	52	47.0769	heterocephalus_glaber_female	ENSHGLP00000054189	86.6667	78.4615
ENSG00000181026	homo_sapiens	ENSP00000331944	95.0769	92.9231	rhinopithecus_bieti	ENSRBIP00000014841	95.0769	92.9231
ENSG00000181026	homo_sapiens	ENSP00000331944	87.3846	82.4615	canis_lupus_dingo	ENSCAFP00020023928	87.6543	82.716
ENSG00000181026	homo_sapiens	ENSP00000331944	86.4615	81.5385	sciurus_vulgaris	ENSSVLP00005004377	86.1963	81.2883
ENSG00000181026	homo_sapiens	ENSP00000331944	68	57.2308	phascolarctos_cinereus	ENSPCIP00000007629	61.9048	52.1008
ENSG00000181026	homo_sapiens	ENSP00000331944	63.3846	57.8462	procavia_capensis	ENSPCAP00000014445	65.8147	60.0639
ENSG00000181026	homo_sapiens	ENSP00000331944	83.0769	76.6154	nannospalax_galili	ENSNGAP00000008684	84.1122	77.5701
ENSG00000181026	homo_sapiens	ENSP00000331944	75.0769	67.3846	bos_grunniens	ENSBGRP00000020426	67.2176	60.3306
ENSG00000181026	homo_sapiens	ENSP00000331944	83.3846	77.8462	chinchilla_lanigera	ENSCLAP00000012734	84.6875	79.0625
ENSG00000181026	homo_sapiens	ENSP00000331944	85.2308	80	cervus_hanglu_yarkandensis	ENSCHYP00000013216	84.7095	79.5107
ENSG00000181026	homo_sapiens	ENSP00000331944	87.6923	81.8462	catagonus_wagneri	ENSCWAP00000004794	87.6923	81.8462
ENSG00000181026	homo_sapiens	ENSP00000331944	49.2308	47.6923	ictidomys_tridecemlineatus	ENSSTOP00000010373	89.8876	87.0787
ENSG00000181026	homo_sapiens	ENSP00000331944	87.6923	84.6154	otolemur_garnettii	ENSOGAP00000016927	85.8434	82.8313
ENSG00000181026	homo_sapiens	ENSP00000331944	95.0769	91.3846	cebus_imitator	ENSCCAP00000038659	95.0769	91.3846
ENSG00000181026	homo_sapiens	ENSP00000331944	86.4615	82.1538	urocitellus_parryii	ENSUPAP00010020685	77.6243	73.7569
ENSG00000181026	homo_sapiens	ENSP00000331944	86.4615	80.9231	moschus_moschiferus	ENSMMSP00000016279	85.9327	80.4281
ENSG00000181026	homo_sapiens	ENSP00000331944	95.3846	93.5385	rhinopithecus_roxellana	ENSRROP00000039975	95.3846	93.5385
ENSG00000181026	homo_sapiens	ENSP00000331944	80.6154	73.2308	mus_pahari	MGP_PahariEiJ_P0017039	77.9762	70.8333
ENSG00000181026	homo_sapiens	ENSP00000331944	90.7692	87.3846	propithecus_coquereli	ENSPCOP00000018109	90.7692	87.3846
ENSG00000181026	homo_sapiens	ENSP00000331944	38.4615	22.4615	caenorhabditis_elegans	F52C9.8b.1	7.58956	4.4323
ENSG00000181026	homo_sapiens	ENSP00000331944	28.6154	17.5385	drosophila_melanogaster	FBpp0099868	9.38446	5.75177
ENSG00000181026	homo_sapiens	ENSP00000331944	38.7692	22.4615	drosophila_melanogaster	FBpp0301696	14.7887	8.56808
ENSG00000181026	homo_sapiens	ENSP00000331944	22.4615	13.5385	ciona_intestinalis	ENSCINP00000016565	47.0968	28.3871
ENSG00000181026	homo_sapiens	ENSP00000331944	33.8462	21.5385	lepisosteus_oculatus	ENSLOCP00000003775	10.4662	6.66032
ENSG00000181026	homo_sapiens	ENSP00000331944	36	22.1538	lepisosteus_oculatus	ENSLOCP00000001371	9.799	6.03015
ENSG00000181026	homo_sapiens	ENSP00000331944	31.3846	19.6923	clupea_harengus	ENSCHAP00000028109	9.19748	5.77096
ENSG00000181026	homo_sapiens	ENSP00000331944	33.8462	19.6923	danio_rerio	ENSDARP00000122980	8.79297	5.11591
ENSG00000181026	homo_sapiens	ENSP00000331944	36.6154	21.8462	danio_rerio	ENSDARP00000074070	9.85915	5.88235
ENSG00000181026	homo_sapiens	ENSP00000331944	32.6154	18.1538	carassius_auratus	ENSCARP00000051015	8.70279	4.84401
ENSG00000181026	homo_sapiens	ENSP00000331944	36.6154	21.5385	carassius_auratus	ENSCARP00000071025	9.81039	5.77082
ENSG00000181026	homo_sapiens	ENSP00000331944	36.9231	21.8462	carassius_auratus	ENSCARP00000082235	9.85222	5.82923
ENSG00000181026	homo_sapiens	ENSP00000331944	29.2308	17.5385	carassius_auratus	ENSCARP00000123768	29.595	17.757
ENSG00000181026	homo_sapiens	ENSP00000331944	32.6154	19.3846	astyanax_mexicanus	ENSAMXP00000046967	8.3007	4.93344
ENSG00000181026	homo_sapiens	ENSP00000331944	37.2308	21.8462	astyanax_mexicanus	ENSAMXP00000016956	9.43102	5.53391
ENSG00000181026	homo_sapiens	ENSP00000331944	33.2308	19.6923	ictalurus_punctatus	ENSIPUP00000006687	12.8419	7.60999
ENSG00000181026	homo_sapiens	ENSP00000331944	37.5385	21.8462	ictalurus_punctatus	ENSIPUP00000020162	9.91064	5.76767
ENSG00000181026	homo_sapiens	ENSP00000331944	30.1538	19.0769	esox_lucius	ENSELUP00000014204	8.72663	5.52093
ENSG00000181026	homo_sapiens	ENSP00000331944	36.9231	21.8462	esox_lucius	ENSELUP00000014000	9.18133	5.43229
ENSG00000181026	homo_sapiens	ENSP00000331944	27.3846	16.6154	electrophorus_electricus	ENSEEEP00000012781	20	12.1348
ENSG00000181026	homo_sapiens	ENSP00000331944	38.1538	23.0769	electrophorus_electricus	ENSEEEP00000011996	10.2564	6.20347
ENSG00000181026	homo_sapiens	ENSP00000331944	29.2308	17.5385	oncorhynchus_kisutch	ENSOKIP00005044867	20.2991	12.1795
ENSG00000181026	homo_sapiens	ENSP00000331944	37.5385	22.4615	oncorhynchus_kisutch	ENSOKIP00005100342	9.58366	5.73449
ENSG00000181026	homo_sapiens	ENSP00000331944	37.2308	23.0769	oncorhynchus_kisutch	ENSOKIP00005092488	9.25076	5.73394
ENSG00000181026	homo_sapiens	ENSP00000331944	28.6154	17.5385	oncorhynchus_mykiss	ENSOMYP00000127002	21.0407	12.8959
ENSG00000181026	homo_sapiens	ENSP00000331944	37.5385	22.4615	oncorhynchus_mykiss	ENSOMYP00000034998	9.54617	5.71205
ENSG00000181026	homo_sapiens	ENSP00000331944	37.2308	23.0769	oncorhynchus_mykiss	ENSOMYP00000024732	9.21554	5.71211
ENSG00000181026	homo_sapiens	ENSP00000331944	28.6154	17.5385	salmo_salar	ENSSSAP00000164321	22.0903	13.5392
ENSG00000181026	homo_sapiens	ENSP00000331944	37.5385	22.7692	salmo_salar	ENSSSAP00000168470	9.39908	5.70108
ENSG00000181026	homo_sapiens	ENSP00000331944	30.7692	20	salmo_salar	ENSSSAP00000026396	20.5761	13.3745
ENSG00000181026	homo_sapiens	ENSP00000331944	33.5385	19.0769	salmo_trutta	ENSSTUP00000020960	10.1584	5.77819
ENSG00000181026	homo_sapiens	ENSP00000331944	37.2308	23.0769	salmo_trutta	ENSSTUP00000098822	9.20852	5.70776
ENSG00000181026	homo_sapiens	ENSP00000331944	37.5385	22.7692	salmo_trutta	ENSSTUP00000054287	9.2917	5.63595
ENSG00000181026	homo_sapiens	ENSP00000331944	29.8462	16.6154	gadus_morhua	ENSGMOP00000019087	21.7489	12.1076
ENSG00000181026	homo_sapiens	ENSP00000331944	36.6154	20.9231	gadus_morhua	ENSGMOP00000011909	9.21053	5.26316
ENSG00000181026	homo_sapiens	ENSP00000331944	32.6154	19.0769	fundulus_heteroclitus	ENSFHEP00000022933	9.33099	5.45775
ENSG00000181026	homo_sapiens	ENSP00000331944	32.6154	19.6923	fundulus_heteroclitus	ENSFHEP00000034341	8.7531	5.28489
ENSG00000181026	homo_sapiens	ENSP00000331944	32	19.0769	poecilia_reticulata	ENSPREP00000010991	9.48905	5.65693
ENSG00000181026	homo_sapiens	ENSP00000331944	36.9231	22.1538	poecilia_reticulata	ENSPREP00000012247	9.69305	5.81583
ENSG00000181026	homo_sapiens	ENSP00000331944	32	19.3846	xiphophorus_maculatus	ENSXMAP00000036036	9.22804	5.59006
ENSG00000181026	homo_sapiens	ENSP00000331944	37.2308	22.7692	xiphophorus_maculatus	ENSXMAP00000002688	9.79757	5.9919
ENSG00000181026	homo_sapiens	ENSP00000331944	36.3077	21.2308	oryzias_latipes	ENSORLP00000011268	9.68801	5.66502
ENSG00000181026	homo_sapiens	ENSP00000331944	28.3077	18.4615	cyclopterus_lumpus	ENSCLMP00005000162	17.4242	11.3636
ENSG00000181026	homo_sapiens	ENSP00000331944	34.7692	19.6923	oreochromis_niloticus	ENSONIP00000043343	9.7079	5.49828
ENSG00000181026	homo_sapiens	ENSP00000331944	36.9231	22.4615	oreochromis_niloticus	ENSONIP00000052687	9.53137	5.79825
ENSG00000181026	homo_sapiens	ENSP00000331944	30.4615	16	haplochromis_burtoni	ENSHBUP00000006152	8.55661	4.49438
ENSG00000181026	homo_sapiens	ENSP00000331944	37.8462	22.4615	haplochromis_burtoni	ENSHBUP00000023903	9.76966	5.79825
ENSG00000181026	homo_sapiens	ENSP00000331944	34.1538	19.6923	astatotilapia_calliptera	ENSACLP00000030355	9.56897	5.51724
ENSG00000181026	homo_sapiens	ENSP00000331944	37.8462	22.4615	astatotilapia_calliptera	ENSACLP00000017186	9.76966	5.79825
ENSG00000181026	homo_sapiens	ENSP00000331944	34.1538	19.3846	sparus_aurata	ENSSAUP00010008671	9.15087	5.19373
ENSG00000181026	homo_sapiens	ENSP00000331944	36.6154	21.8462	sparus_aurata	ENSSAUP00010053947	9.41456	5.61709
ENSG00000181026	homo_sapiens	ENSP00000331944	32.3077	18.4615	lates_calcarifer	ENSLCAP00010036711	12.6506	7.22892
ENSG00000181026	homo_sapiens	ENSP00000331944	36.6154	22.4615	lates_calcarifer	ENSLCAP00010015476	9.35535	5.73899
ENSG00000181026	homo_sapiens	ENSP00000331944	64.3077	50.7692	chrysemys_picta_bellii	ENSCPBP00000025141	50.1199	39.5683
ENSG00000181026	homo_sapiens	ENSP00000331944	65.2308	50.7692	serinus_canaria	ENSSCAP00000007466	57.2973	44.5946
ENSG00000181026	homo_sapiens	ENSP00000331944	63.6923	51.6923	parus_major	ENSPMJP00000001496	57.9832	47.0588
ENSG00000181026	homo_sapiens	ENSP00000331944	6.46154	4	neolamprologus_brichardi	ENSNBRP00000030488	4.7191	2.92135
ENSG00000181026	homo_sapiens	ENSP00000331944	32.9231	19.0769	neolamprologus_brichardi	ENSNBRP00000028188	8.79211	5.09449
ENSG00000181026	homo_sapiens	ENSP00000331944	64.9231	52.9231	geospiza_fortis	ENSGFOP00000000782	61.8768	50.4399
ENSG00000181026	homo_sapiens	ENSP00000331944	63.0769	50.4615	taeniopygia_guttata	ENSTGUP00000008584	57.7465	46.1972
ENSG00000181026	homo_sapiens	ENSP00000331944	35.3846	21.8462	erpetoichthys_calabaricus	ENSECRP00000033489	9.60735	5.9315
ENSG00000181026	homo_sapiens	ENSP00000331944	31.3846	18.1538	kryptolebias_marmoratus	ENSKMAP00000010761	10.8165	6.25663
ENSG00000181026	homo_sapiens	ENSP00000331944	37.5385	22.1538	kryptolebias_marmoratus	ENSKMAP00000019162	9.78348	5.77386
ENSG00000181026	homo_sapiens	ENSP00000331944	23.0769	11.6923	oryzias_javanicus	ENSOJAP00000036177	7.95334	4.02969
ENSG00000181026	homo_sapiens	ENSP00000331944	35.3846	20.6154	oryzias_javanicus	ENSOJAP00000035684	9.63149	5.61139
ENSG00000181026	homo_sapiens	ENSP00000331944	32.6154	17.5385	amphilophus_citrinellus	ENSACIP00000003193	11.3006	6.07676
ENSG00000181026	homo_sapiens	ENSP00000331944	36	22.4615	amphilophus_citrinellus	ENSACIP00000016153	9.48136	5.91572
ENSG00000181026	homo_sapiens	ENSP00000331944	34.1538	20	dicentrarchus_labrax	ENSDLAP00005081968	9.12829	5.34539
ENSG00000181026	homo_sapiens	ENSP00000331944	36.9231	21.2308	dicentrarchus_labrax	ENSDLAP00005063765	9.46372	5.44164
ENSG00000181026	homo_sapiens	ENSP00000331944	32	17.5385	amphiprion_percula	ENSAPEP00000017595	9.66543	5.2974
ENSG00000181026	homo_sapiens	ENSP00000331944	37.2308	22.1538	amphiprion_percula	ENSAPEP00000010743	9.55766	5.6872
ENSG00000181026	homo_sapiens	ENSP00000331944	28.6154	17.8462	oryzias_sinensis	ENSOSIP00000006412	25.4098	15.847
ENSG00000181026	homo_sapiens	ENSP00000331944	36	20.9231	oryzias_sinensis	ENSOSIP00000026461	9.47368	5.50607
ENSG00000181026	homo_sapiens	ENSP00000331944	61.8462	49.8462	pelodiscus_sinensis	ENSPSIP00000016018	66.5563	53.6424
ENSG00000181026	homo_sapiens	ENSP00000331944	65.2308	51.3846	gopherus_evgoodei	ENSGEVP00005009266	53.1328	41.8546
ENSG00000181026	homo_sapiens	ENSP00000331944	33.5385	19.0769	seriola_dumerili	ENSSDUP00000031036	9.40466	5.34944
ENSG00000181026	homo_sapiens	ENSP00000331944	36.6154	22.1538	seriola_dumerili	ENSSDUP00000014875	9.36271	5.66483
ENSG00000181026	homo_sapiens	ENSP00000331944	33.8462	19.3846	cottoperca_gobio	ENSCGOP00000028928	9.16667	5.25
ENSG00000181026	homo_sapiens	ENSP00000331944	34.1538	20.3077	cottoperca_gobio	ENSCGOP00000017560	9.32773	5.54622
ENSG00000181026	homo_sapiens	ENSP00000331944	63.0769	50.7692	anser_brachyrhynchus	ENSABRP00000026175	65.2866	52.5478
ENSG00000181026	homo_sapiens	ENSP00000331944	28.9231	16.3077	gasterosteus_aculeatus	ENSGACP00000018317	27.1676	15.3179
ENSG00000181026	homo_sapiens	ENSP00000331944	36	21.2308	gasterosteus_aculeatus	ENSGACP00000010233	10.354	6.10619
ENSG00000181026	homo_sapiens	ENSP00000331944	32	18.4615	cynoglossus_semilaevis	ENSCSEP00000029627	9.88593	5.70342
ENSG00000181026	homo_sapiens	ENSP00000331944	24.3077	14.1538	cynoglossus_semilaevis	ENSCSEP00000022080	14.4424	8.40951
ENSG00000181026	homo_sapiens	ENSP00000331944	36.3077	21.5385	cynoglossus_semilaevis	ENSCSEP00000026132	9.33544	5.53797
ENSG00000181026	homo_sapiens	ENSP00000331944	32	19.0769	poecilia_formosa	ENSPFOP00000006035	9.22804	5.50133
ENSG00000181026	homo_sapiens	ENSP00000331944	36.9231	22.4615	poecilia_formosa	ENSPFOP00000015627	9.69305	5.89661
ENSG00000181026	homo_sapiens	ENSP00000331944	33.5385	20.9231	myripristis_murdjan	ENSMMDP00005018191	9.16737	5.71909
ENSG00000181026	homo_sapiens	ENSP00000331944	36	20.9231	myripristis_murdjan	ENSMMDP00005015014	9.01387	5.23883
ENSG00000181026	homo_sapiens	ENSP00000331944	32.6154	19.3846	sander_lucioperca	ENSSLUP00000017928	11.3856	6.76692
ENSG00000181026	homo_sapiens	ENSP00000331944	29.8462	18.7692	sander_lucioperca	ENSSLUP00000015061	18.9453	11.9141
ENSG00000181026	homo_sapiens	ENSP00000331944	66.4615	52.9231	strigops_habroptila	ENSSHBP00005012485	60	47.7778
ENSG00000181026	homo_sapiens	ENSP00000331944	32.6154	17.8462	amphiprion_ocellaris	ENSAOCP00000028415	9.34744	5.11464
ENSG00000181026	homo_sapiens	ENSP00000331944	37.2308	22.1538	amphiprion_ocellaris	ENSAOCP00000019555	9.55766	5.6872
ENSG00000181026	homo_sapiens	ENSP00000331944	50.7692	43.0769	terrapene_carolina_triunguis	ENSTMTP00000029751	77.8302	66.0377
ENSG00000181026	homo_sapiens	ENSP00000331944	28.3077	17.5385	hucho_hucho	ENSHHUP00000079348	21.8527	13.5392
ENSG00000181026	homo_sapiens	ENSP00000331944	37.2308	22.7692	hucho_hucho	ENSHHUP00000084352	9.19453	5.6231
ENSG00000181026	homo_sapiens	ENSP00000331944	37.5385	23.0769	hucho_hucho	ENSHHUP00000036058	9.33435	5.73833
ENSG00000181026	homo_sapiens	ENSP00000331944	35.0769	20.6154	betta_splendens	ENSBSLP00000021267	9.87868	5.80589
ENSG00000181026	homo_sapiens	ENSP00000331944	36.9231	21.8462	betta_splendens	ENSBSLP00000052673	9.52381	5.63492
ENSG00000181026	homo_sapiens	ENSP00000331944	32	19.0769	pygocentrus_nattereri	ENSPNAP00000012974	8.24742	4.91673
ENSG00000181026	homo_sapiens	ENSP00000331944	36.6154	21.5385	pygocentrus_nattereri	ENSPNAP00000035449	9.53526	5.60897
ENSG00000181026	homo_sapiens	ENSP00000331944	32.6154	18.7692	anabas_testudineus	ENSATEP00000067738	11.349	6.53105
ENSG00000181026	homo_sapiens	ENSP00000331944	36.9231	21.8462	anabas_testudineus	ENSATEP00000025414	9.48617	5.61265
ENSG00000181026	homo_sapiens	ENSP00000331944	30.7692	17.2308	saccharomyces_cerevisiae	YLR107W	24.7525	13.8614
ENSG00000181026	homo_sapiens	ENSP00000331944	32.6154	18.1538	seriola_lalandi_dorsalis	ENSSLDP00000024133	10.1049	5.6244
ENSG00000181026	homo_sapiens	ENSP00000331944	36.6154	22.1538	seriola_lalandi_dorsalis	ENSSLDP00000003813	9.36271	5.66483
ENSG00000181026	homo_sapiens	ENSP00000331944	32.3077	19.3846	labrus_bergylta	ENSLBEP00000035304	10.8696	6.52174
ENSG00000181026	homo_sapiens	ENSP00000331944	36.3077	20.3077	labrus_bergylta	ENSLBEP00000035876	10.7566	6.01641
ENSG00000181026	homo_sapiens	ENSP00000331944	6.76923	4	pundamilia_nyererei	ENSPNYP00000023193	4.72103	2.7897
ENSG00000181026	homo_sapiens	ENSP00000331944	37.5385	22.4615	pundamilia_nyererei	ENSPNYP00000018351	9.69023	5.79825
ENSG00000181026	homo_sapiens	ENSP00000331944	31.3846	18.7692	mastacembelus_armatus	ENSMAMP00000008744	11.5124	6.88488
ENSG00000181026	homo_sapiens	ENSP00000331944	35.6923	21.5385	mastacembelus_armatus	ENSMAMP00000010741	9.19905	5.55115
ENSG00000181026	homo_sapiens	ENSP00000331944	32.9231	19.0769	stegastes_partitus	ENSSPAP00000010025	10.5419	6.10837
ENSG00000181026	homo_sapiens	ENSP00000331944	34.1538	20.3077	stegastes_partitus	ENSSPAP00000027363	8.75394	5.20505
ENSG00000181026	homo_sapiens	ENSP00000331944	37.2308	23.0769	oncorhynchus_tshawytscha	ENSOTSP00005058465	9.21554	5.71211
ENSG00000181026	homo_sapiens	ENSP00000331944	37.5385	22.4615	oncorhynchus_tshawytscha	ENSOTSP00005034250	9.33435	5.58531
ENSG00000181026	homo_sapiens	ENSP00000331944	32.6154	17.5385	acanthochromis_polyacanthus	ENSAPOP00000023339	12.5592	6.75355
ENSG00000181026	homo_sapiens	ENSP00000331944	37.2308	22.4615	acanthochromis_polyacanthus	ENSAPOP00000009914	9.55766	5.76619
ENSG00000181026	homo_sapiens	ENSP00000331944	37.5385	21.2308	nothobranchius_furzeri	ENSNFUP00015035415	10.2607	5.8032
ENSG00000181026	homo_sapiens	ENSP00000331944	33.2308	18.7692	cyprinodon_variegatus	ENSCVAP00000012920	12.1485	6.86164
ENSG00000181026	homo_sapiens	ENSP00000331944	36.9231	22.4615	cyprinodon_variegatus	ENSCVAP00000008965	9.72447	5.91572
ENSG00000181026	homo_sapiens	ENSP00000331944	29.8462	16.9231	denticeps_clupeoides	ENSDCDP00000039220	9.0739	5.145
ENSG00000181026	homo_sapiens	ENSP00000331944	36.6154	21.5385	denticeps_clupeoides	ENSDCDP00000038904	9.58904	5.64061
ENSG00000181026	homo_sapiens	ENSP00000331944	33.2308	19.3846	larimichthys_crocea	ENSLCRP00005060589	9.04523	5.27638
ENSG00000181026	homo_sapiens	ENSP00000331944	36	21.8462	larimichthys_crocea	ENSLCRP00005041474	9.271	5.62599
ENSG00000181026	homo_sapiens	ENSP00000331944	33.2308	18.1538	takifugu_rubripes	ENSTRUP00000048660	13.8284	7.55442
ENSG00000181026	homo_sapiens	ENSP00000331944	37.5385	22.7692	takifugu_rubripes	ENSTRUP00000012490	9.77564	5.92949
ENSG00000181026	homo_sapiens	ENSP00000331944	56.3077	41.2308	ficedula_albicollis	ENSFALP00000020575	48.0315	35.1706
ENSG00000181026	homo_sapiens	ENSP00000331944	29.8462	20.3077	hippocampus_comes	ENSHCOP00000028027	10.2537	6.97674
ENSG00000181026	homo_sapiens	ENSP00000331944	36.9231	21.2308	hippocampus_comes	ENSHCOP00000020894	10	5.75
ENSG00000181026	homo_sapiens	ENSP00000331944	6.76923	1.84615	cyprinus_carpio_carpio	ENSCCRP00000049523	5.40541	1.4742
ENSG00000181026	homo_sapiens	ENSP00000331944	32.6154	18.1538	cyprinus_carpio_carpio	ENSCCRP00000051012	8.70994	4.84799
ENSG00000181026	homo_sapiens	ENSP00000331944	36.9231	21.8462	cyprinus_carpio_carpio	ENSCCRP00000087538	9.91736	5.86777
ENSG00000181026	homo_sapiens	ENSP00000331944	37.5385	21.5385	cyprinus_carpio_carpio	ENSCCRP00000144765	9.81496	5.63154
ENSG00000181026	homo_sapiens	ENSP00000331944	32.3077	19.3846	poecilia_latipinna	ENSPLAP00000021342	9.75836	5.85502
ENSG00000181026	homo_sapiens	ENSP00000331944	36.9231	22.4615	poecilia_latipinna	ENSPLAP00000004651	9.70089	5.90137
ENSG00000181026	homo_sapiens	ENSP00000331944	33.2308	18.7692	sinocyclocheilus_grahami	ENSSGRP00000062620	8.90355	5.02885
ENSG00000181026	homo_sapiens	ENSP00000331944	36.9231	21.8462	sinocyclocheilus_grahami	ENSSGRP00000031256	10.0251	5.9315
ENSG00000181026	homo_sapiens	ENSP00000331944	36.9231	21.8462	sinocyclocheilus_grahami	ENSSGRP00000026258	9.85222	5.82923
ENSG00000181026	homo_sapiens	ENSP00000331944	34.1538	19.6923	maylandia_zebra	ENSMZEP00005018364	9.56897	5.51724
ENSG00000181026	homo_sapiens	ENSP00000331944	37.8462	22.4615	maylandia_zebra	ENSMZEP00005025319	9.76966	5.79825
ENSG00000181026	homo_sapiens	ENSP00000331944	36.6154	22.1538	tetraodon_nigroviridis	ENSTNIP00000013065	9.79424	5.92593
ENSG00000181026	homo_sapiens	ENSP00000331944	33.2308	20	paramormyrops_kingsleyae	ENSPKIP00000033928	9.31034	5.60345
ENSG00000181026	homo_sapiens	ENSP00000331944	36	21.2308	paramormyrops_kingsleyae	ENSPKIP00000034626	9.14062	5.39062
ENSG00000181026	homo_sapiens	ENSP00000331944	36.6154	22.4615	scleropages_formosus	ENSSFOP00015001808	9.36271	5.74351
ENSG00000181026	homo_sapiens	ENSP00000331944	32.9231	19.6923	scophthalmus_maximus	ENSSMAP00000013257	8.93155	5.34224
ENSG00000181026	homo_sapiens	ENSP00000331944	35.0769	20	scophthalmus_maximus	ENSSMAP00000038360	8.8993	5.07416
ENSG00000181026	homo_sapiens	ENSP00000331944	31.3846	17.2308	oryzias_melastigma	ENSOMEP00000007689	11.8605	6.51163
ENSG00000181026	homo_sapiens	ENSP00000331944	35.6923	20.9231	oryzias_melastigma	ENSOMEP00000004227	9.37753	5.49717

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0003676	enables nucleic acid binding	1	IEA	Homo_sapiens(9606)	Function
GO:0004527	enables exonuclease activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0004529	enables DNA exonuclease activity	1	IDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	1	IBA	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0005730	located_in nucleolus	1	IDA	Homo_sapiens(9606)	Component
GO:0006259	involved_in DNA metabolic process	1	IEA	Homo_sapiens(9606)	Process
GO:0010212	involved_in response to ionizing radiation	1	IDA	Homo_sapiens(9606)	Process
GO:0031965	located_in nuclear membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0042771	involved_in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	2	IBA,IDA	Homo_sapiens(9606)	Process