Ensembl ID
ENSG00000181026
Gene ID
64782
Accession
25722
Gene Symbol
AEN
Alias
ISG20L1;pp12744
Full Name
apoptosis enhancing nuclease
Position
15 : 88621340 - 88632281
Length
10942 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs diverse RBP type
Canonical_RBPs
Summary
Enables exonuclease activity. Involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and response to ionizing radiation. Located in nuclear membrane; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
ENSG00000181026 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000181026
AEN
1.38
1.60e-86
KIRC
ENSG00000181026
AEN
0.42
4.61e-13
BRCA
ENSG00000181026
AEN
1.37
5.36e-44
COAD
ENSG00000181026
AEN
1.62
5.08e-21
KICH
ENSG00000181026
AEN
1.22
1.73e-44
KIRP
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000181026
AEN
tumour
19382019
ENSG00000181026
AEN
cancer
20429933
ENSG00000181026
AEN
tumor
24748736
ENSG00000181026
AEN
breast cancer
26921029
ENSG00000181026
AEN
cancer
27158268
ENSG00000181026
AEN
tumour
29463228
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000181026
AEN
MESO
0.0016
high
show
ENSG00000181026
AEN
STAD
0.0051
low
show
ENSG00000181026
AEN
UVM
0.00057
high
show
ENSG00000181026
AEN
THCA
0.016
high
show
ENSG00000181026
AEN
HNSC
0.041
high
show
ENSG00000181026
AEN
KIRP
0.0042
low
show
ENSG00000181026
AEN
LUAD
0.049
high
show
ENSG00000181026
AEN
THYM
0.0013
low
show
ENSG00000181026
AEN
COAD
0.012
high
show
ENSG00000181026
AEN
UCS
0.024
high
show
ENSG00000181026
AEN
OV
0.023
low
show
ENSG00000181026
AEN
KIRC
0.0023
low
show
ENSG00000181026
AEN
PRAD
0.035
high
show
ENSG00000181026
AEN
BLCA
0.0047
high
show
ENSG00000181026
AEN
GBM
0.033
high
show
ENSG00000181026
AEN
SKCM
0.002
high
show
ENSG00000181026
AEN
CESC
0.035
low
show
ENSG00000181026
AEN
LIHC
0.033
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000181026
AEN
CESC
Amp
1.595064
0.163303
0.545523
0.250847
ENSG00000181026
AEN
SKCM
Amp
3.549693
0.204249
0.542140
0.318801
ENSG00000181026
AEN
BRCA
Amp
1.269855
0.157156
0.565901
0.162963
ENSG00000181026
AEN
STAD
Amp
4.209120
0.221085
0.566590
0.213152
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