Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions E3 ligase
Localizations N.A.
BulkPerturb-seq DataSet_02_75

Description

Ensembl ID ENSG00000179526 Gene ID 81858 Accession 25321
Symbol SHARPIN Alias SIPL1 Full Name SHANK associated RH domain interactor
Status Confidence Length 5605 bases Strand Minus strand
Position 8 : 144098633 - 144104237 RNA binding domain zf-RanBP
Summary Enables polyubiquitin modification-dependent protein binding activity. Involved in protein linear polyubiquitination and regulation of signal transduction. Located in cytosol. Part of LUBAC complex. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000432355 zf-RanBP PF00641 2.4e-06 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
SHARPIN-206 ENST00000532536 533 95aa ENSP00000432355
SHARPIN-202 ENST00000398712 1348 387aa ENSP00000381698
SHARPIN-201 ENST00000359551 1687 326aa ENSP00000352551
SHARPIN-204 ENST00000530216 673 No protein -
SHARPIN-209 ENST00000534242 933 No protein -
SHARPIN-203 ENST00000525275 521 No protein -
SHARPIN-208 ENST00000533948 981 No protein -
SHARPIN-210 ENST00000534435 656 No protein -
SHARPIN-205 ENST00000531375 613 No protein -
SHARPIN-207 ENST00000533184 352 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
75849Metabolism6E-11024816252

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000179526homo_sapiensENSP0000034863224.509818.4314homo_sapiensENSP0000038169832.299724.2894
ENSG00000179526homo_sapiensENSP0000037455210.07585.95883homo_sapiensENSP0000038169824.03114.2119

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000179526homo_sapiensENSP0000038169883.720983.2041nomascus_leucogenysENSNLEP0000001273695.294194.7059
ENSG00000179526homo_sapiensENSP0000038169898.70898.4496pan_paniscusENSPPAP0000002742998.70898.4496
ENSG00000179526homo_sapiensENSP0000038169897.157696.6408pongo_abeliiENSPPYP0000002126797.157696.6408
ENSG00000179526homo_sapiensENSP0000038169898.966498.708pan_troglodytesENSPTRP0000005937098.966498.708
ENSG00000179526homo_sapiensENSP0000038169897.932897.9328gorilla_gorillaENSGGOP0000002063197.932897.9328
ENSG00000179526homo_sapiensENSP0000038169863.565951.938sarcophilus_harrisiiENSSHAP0000000695059.708748.7864
ENSG00000179526homo_sapiensENSP0000038169858.397947.5452notamacropus_eugeniiENSMEUP0000000295067.867955.2553
ENSG00000179526homo_sapiensENSP0000038169853.488446.77dasypus_novemcinctusENSDNOP0000002177564.285756.2112
ENSG00000179526homo_sapiensENSP0000038169857.881150.9044erinaceus_europaeusENSEEUP0000000462958.792751.706
ENSG00000179526homo_sapiensENSP0000038169870.025863.8243echinops_telfairiENSETEP0000001238969.309563.1714
ENSG00000179526homo_sapiensENSP0000038169893.798491.7313callithrix_jacchusENSCJAP0000003992793.556791.4948
ENSG00000179526homo_sapiensENSP0000038169895.090494.3152cercocebus_atysENSCATP0000002589996.083595.3003
ENSG00000179526homo_sapiensENSP0000038169871.576268.2171macaca_fascicularisENSMFAP0000003904865.023561.9718
ENSG00000179526homo_sapiensENSP0000038169894.83293.7984macaca_mulattaENSMMUP0000000937396.073395.0262
ENSG00000179526homo_sapiensENSP0000038169894.573693.5401macaca_nemestrinaENSMNEP0000000074795.811594.7644
ENSG00000179526homo_sapiensENSP0000038169894.83294.0568papio_anubisENSPANP0000003106896.073395.288
ENSG00000179526homo_sapiensENSP0000038169879.84579.0698mandrillus_leucophaeusENSMLEP0000000370596.261795.3271
ENSG00000179526homo_sapiensENSP0000038169861.498756.0723tursiops_truncatusENSTTRP0000000607071.471565.1652
ENSG00000179526homo_sapiensENSP0000038169881.136972.6098mus_spretusMGP_SPRETEiJ_P004044582.631673.9474
ENSG00000179526homo_sapiensENSP0000038169887.855383.4625equus_asinusENSEASP0000501459353.968351.2698
ENSG00000179526homo_sapiensENSP0000038169885.271380.8786capra_hircusENSCHIP0000002939565.868362.475
ENSG00000179526homo_sapiensENSP0000038169886.046581.3953panthera_leoENSPLOP0000002952181.617677.2059
ENSG00000179526homo_sapiensENSP0000038169887.596983.2041equus_caballusENSECAP0000000126084.119179.9007
ENSG00000179526homo_sapiensENSP0000038169884.237779.845equus_caballusENSECAP0000000169977.61973.5714
ENSG00000179526homo_sapiensENSP0000038169874.67766.9251canis_lupus_familiarisENSCAFP0084501093535.243931.5854
ENSG00000179526homo_sapiensENSP0000038169886.046581.3953panthera_pardusENSPPRP0000002562988.328983.5544
ENSG00000179526homo_sapiensENSP0000038169884.754577.5194marmota_marmota_marmotaENSMMMP0000000814985.194877.9221
ENSG00000179526homo_sapiensENSP0000038169874.160268.4754balaenoptera_musculusENSBMSP0001002365768.009562.7962
ENSG00000179526homo_sapiensENSP0000038169883.462576.2274cavia_porcellusENSCPOP0000001192284.334277.0235
ENSG00000179526homo_sapiensENSP0000038169886.821782.1705felis_catusENSFCAP0000001072282.352977.9412
ENSG00000179526homo_sapiensENSP0000038169883.720978.553ursus_americanusENSUAMP0000003672860.22356.5056
ENSG00000179526homo_sapiensENSP0000038169864.341152.9716monodelphis_domesticaENSMODP0000001314660.583949.8783
ENSG00000179526homo_sapiensENSP0000038169884.237780.1034bison_bison_bisonENSBBBP0000001300185.789581.5789
ENSG00000179526homo_sapiensENSP0000038169884.754579.845monodon_monocerosENSMMNP0001502220470.995766.8831
ENSG00000179526homo_sapiensENSP0000038169883.720978.2946sus_scrofaENSSSCP000000063238175.75
ENSG00000179526homo_sapiensENSP0000038169887.080181.3953microcebus_murinusENSMICP0000001421487.532581.8182
ENSG00000179526homo_sapiensENSP0000038169884.237776.7442octodon_degusENSODEP0000001748685.117577.5457
ENSG00000179526homo_sapiensENSP0000038169879.84572.093jaculus_jaculusENSJJAP0000000688282.620374.5989
ENSG00000179526homo_sapiensENSP0000038169861.498756.5891ursus_maritimusENSUMAP0000002865757.487952.8986
ENSG00000179526homo_sapiensENSP0000038169884.496179.5866delphinapterus_leucasENSDLEP0000002484470.779266.6667
ENSG00000179526homo_sapiensENSP0000038169885.012980.3618physeter_catodonENSPCTP0000501578480.637376.2255
ENSG00000179526homo_sapiensENSP0000038169880.620272.093mus_caroliMGP_CAROLIEiJ_P003863582.978774.2021
ENSG00000179526homo_sapiensENSP0000038169881.136972.6098mus_musculusENSMUSP0000002321182.631673.9474
ENSG00000179526homo_sapiensENSP0000038169869.250661.2403dipodomys_ordiiENSDORP0000000795282.208672.6994
ENSG00000179526homo_sapiensENSP0000038169877.002669.509mustela_putorius_furoENSMPUP0000000707678.83671.164
ENSG00000179526homo_sapiensENSP0000038169889.405787.5969aotus_nancymaaeENSANAP0000001952393.513591.6216
ENSG00000179526homo_sapiensENSP0000038169892.764990.4393saimiri_boliviensis_boliviensisENSSBOP0000001149193.005290.6736
ENSG00000179526homo_sapiensENSP0000038169894.315293.5401chlorocebus_sabaeusENSCSAP0000000502195.300394.517
ENSG00000179526homo_sapiensENSP0000038169871.576264.8579tupaia_belangeriENSTBEP0000001192669.59863.0653
ENSG00000179526homo_sapiensENSP0000038169884.237778.8114phocoena_sinusENSPSNP0000002919070.562866.0173
ENSG00000179526homo_sapiensENSP0000038169885.788179.5866camelus_dromedariusENSCDRP0000502130181.173675.3056
ENSG00000179526homo_sapiensENSP0000038169880.103475.7106carlito_syrichtaENSTSYP0000002512782.666778.1333
ENSG00000179526homo_sapiensENSP0000038169870.025865.6331panthera_tigris_altaicaENSPTIP0000001887371.693167.1958
ENSG00000179526homo_sapiensENSP0000038169879.328272.093rattus_norvegicusENSRNOP0000001803280.577473.2283
ENSG00000179526homo_sapiensENSP0000038169887.596982.1705prolemur_simusENSPSMP0000003680688.743583.2461
ENSG00000179526homo_sapiensENSP0000038169880.620274.677microtus_ochrogasterENSMOCP0000001477882.539776.455
ENSG00000179526homo_sapiensENSP0000038169834.883731.7829sorex_araneusENSSARP0000000510543.269239.4231
ENSG00000179526homo_sapiensENSP0000038169880.620274.9354peromyscus_maniculatus_bairdiiENSPEMP0000000677082.321976.5172
ENSG00000179526homo_sapiensENSP0000038169874.418670.5426bos_mutusENSBMUP0000003205272.180568.4211
ENSG00000179526homo_sapiensENSP0000038169880.103471.5762mus_spicilegusENSMSIP0000002808482.010673.2804
ENSG00000179526homo_sapiensENSP0000038169879.84574.677cricetulus_griseus_chok1gshdENSCGRP0000101507981.962976.6578
ENSG00000179526homo_sapiensENSP0000038169877.777871.3178pteropus_vampyrusENSPVAP0000000670175.062368.8279
ENSG00000179526homo_sapiensENSP0000038169884.496179.845myotis_lucifugusENSMLUP0000000625187.433282.6203
ENSG00000179526homo_sapiensENSP0000038169862.532351.938vombatus_ursinusENSVURP0001003251461.734751.2755
ENSG00000179526homo_sapiensENSP0000038169885.271380.8786rhinolophus_ferrumequinumENSRFEP0001002995980.29276.1557
ENSG00000179526homo_sapiensENSP0000038169847.545243.4109neovison_visonENSNVIP0000003121878.9772.103
ENSG00000179526homo_sapiensENSP0000038169883.979380.1034bos_taurusENSBTAP0000004653079.462175.7946
ENSG00000179526homo_sapiensENSP0000038169886.821780.1034heterocephalus_glaber_femaleENSHGLP0000000810580.769274.5192
ENSG00000179526homo_sapiensENSP0000038169894.83294.3152rhinopithecus_bietiENSRBIP0000003561095.572995.0521
ENSG00000179526homo_sapiensENSP0000038169874.67766.9251canis_lupus_dingoENSCAFP0002002392135.243931.5854
ENSG00000179526homo_sapiensENSP0000038169861.757151.6796phascolarctos_cinereusENSPCIP0000001131363.733353.3333
ENSG00000179526homo_sapiensENSP0000038169861.757156.0723procavia_capensisENSPCAP0000000723260.506354.9367
ENSG00000179526homo_sapiensENSP0000038169880.361874.677nannospalax_galiliENSNGAP0000001162282.05876.2533
ENSG00000179526homo_sapiensENSP0000038169884.237780.3618bos_grunniensENSBGRP0000001842079.318775.6691
ENSG00000179526homo_sapiensENSP0000038169886.304979.5866chinchilla_lanigeraENSCLAP0000001803087.206380.4178
ENSG00000179526homo_sapiensENSP0000038169885.271380.6202cervus_hanglu_yarkandensisENSCHYP0000001721475.170871.0706
ENSG00000179526homo_sapiensENSP0000038169886.046578.8114ictidomys_tridecemlineatusENSSTOP0000000241587.172879.8429
ENSG00000179526homo_sapiensENSP0000038169885.788180.8786otolemur_garnettiiENSOGAP0000000663486.91181.9372
ENSG00000179526homo_sapiensENSP0000038169893.281791.4729cebus_imitatorENSCCAP0000003653493.523391.7098
ENSG00000179526homo_sapiensENSP0000038169886.563380.1034urocitellus_parryiiENSUPAP0001002994888.390581.7942
ENSG00000179526homo_sapiensENSP0000038169894.83294.3152rhinopithecus_roxellanaENSRROP0000003562195.572995.0521
ENSG00000179526homo_sapiensENSP0000038169880.878672.8682mus_pahariMGP_PahariEiJ_P004200782.804274.6032
ENSG00000179526homo_sapiensENSP0000038169881.136975.7106propithecus_coquereliENSPCOP0000003033982.849677.3087
ENSG00000179526homo_sapiensENSP0000038169817.57118.78553ciona_intestinalisENSCINP0000003383113.38586.69291
ENSG00000179526homo_sapiensENSP0000038169849.870833.5917callorhinchus_miliiENSCMIP0000000448226.547517.8817
ENSG00000179526homo_sapiensENSP0000038169847.803633.5917latimeria_chalumnaeENSLACP0000001242827.165919.0896
ENSG00000179526homo_sapiensENSP0000038169827.90720.6718lepisosteus_oculatusENSLOCP0000000804221.862316.1943
ENSG00000179526homo_sapiensENSP0000038169850.64637.9845lepisosteus_oculatusENSLOCP0000001085827.722820.7921
ENSG00000179526homo_sapiensENSP0000038169829.19919.8966clupea_harengusENSCHAP0000003906921.941714.9515
ENSG00000179526homo_sapiensENSP0000038169848.578838.5013clupea_harengusENSCHAP0000004021346.766237.0647
ENSG00000179526homo_sapiensENSP0000038169827.648617.8295danio_rerioENSDARP0000004744320.776713.3981
ENSG00000179526homo_sapiensENSP0000038169849.870836.6925danio_rerioENSDARP0000007815427.030819.888
ENSG00000179526homo_sapiensENSP0000038169846.253236.6925danio_rerioENSDARP0000012824745.431536.0406
ENSG00000179526homo_sapiensENSP0000038169827.648618.3463carassius_auratusENSCARP0000010600621.104514.0039
ENSG00000179526homo_sapiensENSP0000038169827.648618.6047carassius_auratusENSCARP0000008830621.104514.2012
ENSG00000179526homo_sapiensENSP0000038169823.255815.2455carassius_auratusENSCARP0000013043917.751511.6371
ENSG00000179526homo_sapiensENSP0000038169827.648618.6047carassius_auratusENSCARP0000009124821.104514.2012
ENSG00000179526homo_sapiensENSP0000038169849.35436.6925carassius_auratusENSCARP0000012451626.67619.8324
ENSG00000179526homo_sapiensENSP0000038169845.47836.4341carassius_auratusENSCARP0000002040544.332535.5164
ENSG00000179526homo_sapiensENSP0000038169824.289415.5039astyanax_mexicanusENSAMXP0000003666217.184610.9689
ENSG00000179526homo_sapiensENSP0000038169849.612437.7261astyanax_mexicanusENSAMXP0000004346826.482820.1379
ENSG00000179526homo_sapiensENSP0000038169847.803638.7597astyanax_mexicanusENSAMXP0000000639049.071639.7878
ENSG00000179526homo_sapiensENSP0000038169826.61517.3127ictalurus_punctatusENSIPUP0000001474220.07813.0604
ENSG00000179526homo_sapiensENSP0000038169846.511636.1757ictalurus_punctatusENSIPUP0000002102525.423719.774
ENSG00000179526homo_sapiensENSP0000038169846.253237.7261ictalurus_punctatusENSIPUP0000001764449.311340.2204
ENSG00000179526homo_sapiensENSP0000038169828.940619.3798esox_luciusENSELUP0000006749019.649113.1579
ENSG00000179526homo_sapiensENSP0000038169849.612436.6925esox_luciusENSELUP0000001616927.467820.3147
ENSG00000179526homo_sapiensENSP0000038169851.162839.0181esox_luciusENSELUP0000002196444.89834.2404
ENSG00000179526homo_sapiensENSP0000038169827.390217.8295electrophorus_electricusENSEEEP0000001577520.22913.1679
ENSG00000179526homo_sapiensENSP0000038169847.545235.6589electrophorus_electricusENSEEEP0000002698326.062319.5467
ENSG00000179526homo_sapiensENSP0000038169829.715824.5478electrophorus_electricusENSEEEP0000002323449.356240.7725
ENSG00000179526homo_sapiensENSP0000038169829.19919.3798oncorhynchus_kisutchENSOKIP0000505233921.899214.5349
ENSG00000179526homo_sapiensENSP0000038169822.480613.4367oncorhynchus_kisutchENSOKIP0000509394621.065412.5908
ENSG00000179526homo_sapiensENSP0000038169843.669333.3333oncorhynchus_kisutchENSOKIP0000506311525.528719.4864
ENSG00000179526homo_sapiensENSP0000038169845.219634.3669oncorhynchus_kisutchENSOKIP0000506348336.610927.8243
ENSG00000179526homo_sapiensENSP0000038169850.387638.7597oncorhynchus_kisutchENSOKIP0000500797227.464821.1268
ENSG00000179526homo_sapiensENSP0000038169829.19919.3798oncorhynchus_mykissENSOMYP0000001789421.899214.5349
ENSG00000179526homo_sapiensENSP0000038169841.085329.9742oncorhynchus_mykissENSOMYP0000006734828.342220.6774
ENSG00000179526homo_sapiensENSP0000038169849.35437.9845oncorhynchus_mykissENSOMYP0000005778439.958230.7531
ENSG00000179526homo_sapiensENSP0000038169850.387638.7597oncorhynchus_mykissENSOMYP0000014291126.069520.0535
ENSG00000179526homo_sapiensENSP0000038169829.715819.6382salmo_salarENSSSAP0000004038519.327712.7731
ENSG00000179526homo_sapiensENSP0000038169850.387638.7597salmo_salarENSSSAP0000016724344.018133.86
ENSG00000179526homo_sapiensENSP0000038169845.47834.6253salmo_salarENSSSAP0000009156136.590427.8586
ENSG00000179526homo_sapiensENSP0000038169850.387638.5013salmo_salarENSSSAP0000011673027.464820.9859
ENSG00000179526homo_sapiensENSP0000038169850.64639.2765salmo_salarENSSSAP0000000410344.851334.7826
ENSG00000179526homo_sapiensENSP0000038169829.715819.8966salmo_truttaENSSTUP0000000751922.286814.9225
ENSG00000179526homo_sapiensENSP0000038169851.162839.7933salmo_truttaENSSTUP0000011487344.695334.763
ENSG00000179526homo_sapiensENSP0000038169850.387638.5013salmo_truttaENSSTUP0000002990927.464820.9859
ENSG00000179526homo_sapiensENSP0000038169850.387639.2765salmo_truttaENSSTUP0000003953844.622434.7826
ENSG00000179526homo_sapiensENSP0000038169829.974218.863gadus_morhuaENSGMOP0000000074422.612114.23
ENSG00000179526homo_sapiensENSP0000038169850.904439.0181gadus_morhuaENSGMOP0000002888540.204130.8163
ENSG00000179526homo_sapiensENSP0000038169848.578835.9173gadus_morhuaENSGMOP0000003124826.934119.914
ENSG00000179526homo_sapiensENSP0000038169830.749421.7054fundulus_heteroclitusENSFHEP0000003118823.333316.4706
ENSG00000179526homo_sapiensENSP0000038169850.64637.9845fundulus_heteroclitusENSFHEP0000000336626.739420.0546
ENSG00000179526homo_sapiensENSP0000038169848.06235.9173fundulus_heteroclitusENSFHEP0000002906242.660531.8807
ENSG00000179526homo_sapiensENSP0000038169829.457419.8966poecilia_reticulataENSPREP0000001397522.529615.2174
ENSG00000179526homo_sapiensENSP0000038169847.803635.1421poecilia_reticulataENSPREP0000001429542.431231.1927
ENSG00000179526homo_sapiensENSP0000038169848.837236.6925poecilia_reticulataENSPREP0000002174327.077420.3438
ENSG00000179526homo_sapiensENSP0000038169831.007820.4134xiphophorus_maculatusENSXMAP0000000591523.30115.3398
ENSG00000179526homo_sapiensENSP0000038169847.545235.1421xiphophorus_maculatusENSXMAP0000003374242.298931.2644
ENSG00000179526homo_sapiensENSP0000038169846.511634.8837xiphophorus_maculatusENSXMAP0000001901726.200919.6507
ENSG00000179526homo_sapiensENSP0000038169831.524521.447oryzias_latipesENSORLP0000000758623.552116.0232
ENSG00000179526homo_sapiensENSP0000038169848.837237.4677oryzias_latipesENSORLP0000003374939.705930.4622
ENSG00000179526homo_sapiensENSP0000038169848.06235.9173oryzias_latipesENSORLP0000000926326.234119.6051
ENSG00000179526homo_sapiensENSP0000038169822.480614.9871cyclopterus_lumpusENSCLMP0000500155319.037212.6915
ENSG00000179526homo_sapiensENSP0000038169824.806220.155cyclopterus_lumpusENSCLMP0000503027919.712516.0164
ENSG00000179526homo_sapiensENSP0000038169849.612438.5013cyclopterus_lumpusENSCLMP0000504945841.921432.5328
ENSG00000179526homo_sapiensENSP0000038169830.232621.447oreochromis_niloticusENSONIP0000000858622.543415.9923
ENSG00000179526homo_sapiensENSP0000038169849.35437.4677oreochromis_niloticusENSONIP0000001810526.977420.4802
ENSG00000179526homo_sapiensENSP0000038169850.129238.2429oreochromis_niloticusENSONIP0000001209244.495433.945
ENSG00000179526homo_sapiensENSP0000038169830.232621.447haplochromis_burtoniENSHBUP0000000676222.543415.9923
ENSG00000179526homo_sapiensENSP0000038169850.129238.2429haplochromis_burtoniENSHBUP0000000517044.495433.945
ENSG00000179526homo_sapiensENSP0000038169849.095637.7261haplochromis_burtoniENSHBUP0000001973226.722920.5345
ENSG00000179526homo_sapiensENSP0000038169830.232621.447astatotilapia_callipteraENSACLP0000003008122.543415.9923
ENSG00000179526homo_sapiensENSP0000038169833.850125.323astatotilapia_callipteraENSACLP0000002977348.339536.1624
ENSG00000179526homo_sapiensENSP0000038169849.095637.7261astatotilapia_callipteraENSACLP0000003339626.722920.5345
ENSG00000179526homo_sapiensENSP0000038169830.749421.447sparus_aurataENSSAUP0001004094222.666715.8095
ENSG00000179526homo_sapiensENSP0000038169849.35437.9845sparus_aurataENSSAUP0001003725426.825820.6461
ENSG00000179526homo_sapiensENSP0000038169850.64639.0181sparus_aurataENSSAUP0001005598944.954134.633
ENSG00000179526homo_sapiensENSP0000038169825.064616.7959lates_calcariferENSLCAP0001003493020.726513.8889
ENSG00000179526homo_sapiensENSP0000038169850.387637.7261lates_calcariferENSLCAP0001004732127.464820.5634
ENSG00000179526homo_sapiensENSP0000038169850.64638.7597lates_calcariferENSLCAP0001001988245.057534.4828
ENSG00000179526homo_sapiensENSP0000038169845.219630.2326xenopus_tropicalisENSXETP0000006709726.080517.4367
ENSG00000179526homo_sapiensENSP0000038169848.837235.1421chrysemys_picta_belliiENSCPBP0000002655529.485221.2168
ENSG00000179526homo_sapiensENSP0000038169840.826930.7494sphenodon_punctatusENSSPUP0000002337039.59929.8246
ENSG00000179526homo_sapiensENSP0000038169826.356619.6382laticauda_laticaudataENSLLTP0000001693922.921317.0787
ENSG00000179526homo_sapiensENSP0000038169826.098219.6382notechis_scutatusENSNSUP0000002575722.954517.2727
ENSG00000179526homo_sapiensENSP0000038169829.715822.4806pseudonaja_textilisENSPTXP0000002657224.520318.5501
ENSG00000179526homo_sapiensENSP0000038169828.682222.739anas_platyrhynchos_platyrhynchosENSAPLP0000002440825.113119.9095
ENSG00000179526homo_sapiensENSP0000038169851.679640.5685gallus_gallusENSGALP0001001319442.918533.691
ENSG00000179526homo_sapiensENSP0000038169810.85278.52713meleagris_gallopavoENSMGAP0000002452212.4269.76331
ENSG00000179526homo_sapiensENSP0000038169853.488440.3101anolis_carolinensisENSACAP0000000713129.403422.1591
ENSG00000179526homo_sapiensENSP0000038169828.940620.6718neolamprologus_brichardiENSNBRP0000000796623.333316.6667
ENSG00000179526homo_sapiensENSP0000038169849.35437.9845neolamprologus_brichardiENSNBRP0000000285726.863620.6751
ENSG00000179526homo_sapiensENSP0000038169848.837237.2093neolamprologus_brichardiENSNBRP0000001604243.64933.2564
ENSG00000179526homo_sapiensENSP0000038169825.581419.1214naja_najaENSNNAP0000000285022.706416.9725
ENSG00000179526homo_sapiensENSP0000038169831.524523.5142podarcis_muralisENSPMRP0000001592725.311218.8797
ENSG00000179526homo_sapiensENSP0000038169843.152534.8837taeniopygia_guttataENSTGUP0000003251943.947435.5263
ENSG00000179526homo_sapiensENSP0000038169829.457418.6047erpetoichthys_calabaricusENSECRP0000001399621.388413.5084
ENSG00000179526homo_sapiensENSP0000038169848.837232.5581erpetoichthys_calabaricusENSECRP0000001813026.06917.3793
ENSG00000179526homo_sapiensENSP0000038169830.49121.447kryptolebias_marmoratusENSKMAP0000001860322.82416.0542
ENSG00000179526homo_sapiensENSP0000038169848.837236.6925kryptolebias_marmoratusENSKMAP0000002051235.931626.9962
ENSG00000179526homo_sapiensENSP0000038169847.803635.1421kryptolebias_marmoratusENSKMAP0000002050225.730218.9152
ENSG00000179526homo_sapiensENSP0000038169854.52241.3437salvator_merianaeENSSMRP0000001281830.05722.792
ENSG00000179526homo_sapiensENSP0000038169831.524521.7054oryzias_javanicusENSOJAP0000003715023.371616.092
ENSG00000179526homo_sapiensENSP0000038169848.320436.4341oryzias_javanicusENSOJAP0000002977039.534929.8097
ENSG00000179526homo_sapiensENSP0000038169847.545236.1757oryzias_javanicusENSOJAP0000004848426.248219.9715
ENSG00000179526homo_sapiensENSP0000038169828.165419.6382amphilophus_citrinellusENSACIP0000001975921.931615.2918
ENSG00000179526homo_sapiensENSP0000038169849.870838.5013amphilophus_citrinellusENSACIP0000000273427.259921.0452
ENSG00000179526homo_sapiensENSP0000038169840.051729.4574amphilophus_citrinellusENSACIP0000002300853.264639.1753
ENSG00000179526homo_sapiensENSP0000038169831.524522.4806dicentrarchus_labraxENSDLAP0000502832423.781716.9591
ENSG00000179526homo_sapiensENSP0000038169843.410933.5917dicentrarchus_labraxENSDLAP0000505065532.748525.3411
ENSG00000179526homo_sapiensENSP0000038169848.837238.2429dicentrarchus_labraxENSDLAP0000504118326.732720.9335
ENSG00000179526homo_sapiensENSP0000038169829.457419.8966amphiprion_perculaENSAPEP0000002948921.965314.8362
ENSG00000179526homo_sapiensENSP0000038169850.129238.5013amphiprion_perculaENSAPEP0000000562944.393634.0961
ENSG00000179526homo_sapiensENSP0000038169849.35437.4677amphiprion_perculaENSAPEP0000003279827.363920.7736
ENSG00000179526homo_sapiensENSP0000038169832.041321.7054oryzias_sinensisENSOSIP0000002415722.222215.0538
ENSG00000179526homo_sapiensENSP0000038169848.320436.4341oryzias_sinensisENSOSIP0000004914240.215130.3226
ENSG00000179526homo_sapiensENSP0000038169825.581420.155oryzias_sinensisENSOSIP0000003779419.721115.5378
ENSG00000179526homo_sapiensENSP0000038169843.669330.7494gopherus_evgoodeiENSGEVP0000500220126.080218.3642
ENSG00000179526homo_sapiensENSP0000038169829.974223.7726chelonoidis_abingdoniiENSCABP0000001513624.733519.6162
ENSG00000179526homo_sapiensENSP0000038169830.749421.1886seriola_dumeriliENSSDUP0000003289222.666715.619
ENSG00000179526homo_sapiensENSP0000038169842.635733.0749seriola_dumeriliENSSDUP0000002626544.959134.8774
ENSG00000179526homo_sapiensENSP0000038169848.837237.9845seriola_dumeriliENSSDUP0000000396726.808520.8511
ENSG00000179526homo_sapiensENSP0000038169831.524520.9302cottoperca_gobioENSCGOP0000003737423.461515.5769
ENSG00000179526homo_sapiensENSP0000038169848.578838.5013cottoperca_gobioENSCGOP0000003904226.591221.075
ENSG00000179526homo_sapiensENSP0000038169849.870838.2429cottoperca_gobioENSCGOP0000005046537.475728.7379
ENSG00000179526homo_sapiensENSP0000038169824.547818.0879struthio_camelus_australisENSSCUP0000001019532.094623.6486
ENSG00000179526homo_sapiensENSP0000038169855.297240.5685anser_brachyrhynchusENSABRP0000000887530.397722.3011
ENSG00000179526homo_sapiensENSP0000038169818.087913.1783gasterosteus_aculeatusENSGACP0000000801816.746412.201
ENSG00000179526homo_sapiensENSP0000038169814.211910.3359gasterosteus_aculeatusENSGACP0000000333541.984730.5344
ENSG00000179526homo_sapiensENSP0000038169830.49124.5478gasterosteus_aculeatusENSGACP0000000333023.274218.7377
ENSG00000179526homo_sapiensENSP0000038169848.837238.2429gasterosteus_aculeatusENSGACP0000002356546.898336.7246
ENSG00000179526homo_sapiensENSP0000038169823.772615.5039cynoglossus_semilaevisENSCSEP0000002987519.700212.848
ENSG00000179526homo_sapiensENSP0000038169847.803635.6589cynoglossus_semilaevisENSCSEP0000001763026.390919.6862
ENSG00000179526homo_sapiensENSP0000038169840.310129.7158cynoglossus_semilaevisENSCSEP0000001494747.852835.2761
ENSG00000179526homo_sapiensENSP0000038169830.232620.6718poecilia_formosaENSPFOP0000000223022.851615.625
ENSG00000179526homo_sapiensENSP0000038169849.612436.9509poecilia_formosaENSPFOP0000000406127.23420.2837
ENSG00000179526homo_sapiensENSP0000038169847.545235.4005poecilia_formosaENSPFOP0000001529142.298931.4943
ENSG00000179526homo_sapiensENSP0000038169828.940619.1214myripristis_murdjanENSMMDP0000502719823.43115.4812
ENSG00000179526homo_sapiensENSP0000038169851.162840.0517myripristis_murdjanENSMMDP0000502310345.308935.4691
ENSG00000179526homo_sapiensENSP0000038169849.095637.9845myripristis_murdjanENSMMDP0000501371526.573420.5594
ENSG00000179526homo_sapiensENSP0000038169831.524522.739sander_luciopercaENSSLUP0000000101923.689317.0874
ENSG00000179526homo_sapiensENSP0000038169849.612437.9845sander_luciopercaENSSLUP0000000795544.137933.7931
ENSG00000179526homo_sapiensENSP0000038169848.320437.2093sander_luciopercaENSSLUP0000004522626.906520.7194
ENSG00000179526homo_sapiensENSP0000038169845.219633.3333strigops_habroptilaENSSHBP0000500128928.830321.2521
ENSG00000179526homo_sapiensENSP0000038169829.715820.155amphiprion_ocellarisENSAOCP0000003015222.15815.0289
ENSG00000179526homo_sapiensENSP0000038169850.129238.5013amphiprion_ocellarisENSAOCP0000001293644.393634.0961
ENSG00000179526homo_sapiensENSP0000038169849.870837.9845amphiprion_ocellarisENSAOCP0000001948027.106720.6461
ENSG00000179526homo_sapiensENSP0000038169835.917326.0982terrapene_carolina_triunguisENSTMTP0000000273028.600820.7819
ENSG00000179526homo_sapiensENSP0000038169829.457419.6382hucho_huchoENSHHUP0000005411022.09314.7287
ENSG00000179526homo_sapiensENSP0000038169818.604713.6951hucho_huchoENSHHUP0000007410813.766710.1338
ENSG00000179526homo_sapiensENSP0000038169847.545237.7261hucho_huchoENSHHUP0000008291138.983130.9322
ENSG00000179526homo_sapiensENSP0000038169850.387639.5349hucho_huchoENSHHUP0000004053744.318234.7727
ENSG00000179526homo_sapiensENSP0000038169850.387638.5013hucho_huchoENSHHUP0000004234527.464820.9859
ENSG00000179526homo_sapiensENSP0000038169829.715820.4134betta_splendensENSBSLP0000005539922.373515.3696
ENSG00000179526homo_sapiensENSP0000038169848.578837.7261betta_splendensENSBSLP0000001771426.293720.4196
ENSG00000179526homo_sapiensENSP0000038169849.870837.7261betta_splendensENSBSLP0000001335846.28335.012
ENSG00000179526homo_sapiensENSP0000038169827.131818.0879pygocentrus_nattereriENSPNAP0000002248920.309513.5397
ENSG00000179526homo_sapiensENSP0000038169848.06237.9845pygocentrus_nattereriENSPNAP0000002330825.797520.3883
ENSG00000179526homo_sapiensENSP0000038169845.736437.2093pygocentrus_nattereriENSPNAP0000002813951.603541.9825
ENSG00000179526homo_sapiensENSP0000038169830.232621.9638anabas_testudineusENSATEP0000003754922.413816.2835
ENSG00000179526homo_sapiensENSP0000038169847.803636.1757anabas_testudineusENSATEP0000002094226.504320.0573
ENSG00000179526homo_sapiensENSP0000038169850.904438.5013anabas_testudineusENSATEP0000001128845.81434.6512
ENSG00000179526homo_sapiensENSP0000038169800ciona_savignyiENSCSAVP0000001548000
ENSG00000179526homo_sapiensENSP0000038169830.749421.1886seriola_lalandi_dorsalisENSSLDP0000001041122.709915.6489
ENSG00000179526homo_sapiensENSP0000038169848.837237.7261seriola_lalandi_dorsalisENSSLDP0000001138026.657320.5924
ENSG00000179526homo_sapiensENSP0000038169829.715820.155labrus_bergyltaENSLBEP0000003104822.286815.1163
ENSG00000179526homo_sapiensENSP0000038169851.162839.5349labrus_bergyltaENSLBEP0000002163845.412835.0917
ENSG00000179526homo_sapiensENSP0000038169838.242928.9406labrus_bergyltaENSLBEP0000001663549.498337.4582
ENSG00000179526homo_sapiensENSP0000038169850.129238.2429labrus_bergyltaENSLBEP0000002196627.323920.8451
ENSG00000179526homo_sapiensENSP0000038169828.682220.4134pundamilia_nyerereiENSPNYP0000001678921.511615.3101
ENSG00000179526homo_sapiensENSP0000038169850.129238.2429pundamilia_nyerereiENSPNYP0000001897944.495433.945
ENSG00000179526homo_sapiensENSP0000038169849.35437.9845pundamilia_nyerereiENSPNYP0000002996726.863620.6751
ENSG00000179526homo_sapiensENSP0000038169831.782921.1886mastacembelus_armatusENSMAMP0000001247523.563215.7088
ENSG00000179526homo_sapiensENSP0000038169849.35437.7261mastacembelus_armatusENSMAMP0000002183238.047829.0837
ENSG00000179526homo_sapiensENSP0000038169848.578836.1757mastacembelus_armatusENSMAMP0000003410526.742519.9147
ENSG00000179526homo_sapiensENSP0000038169829.457420.6718stegastes_partitusENSSPAP0000001241821.965315.4143
ENSG00000179526homo_sapiensENSP0000038169847.545236.4341stegastes_partitusENSSPAP0000002136826.744220.4942
ENSG00000179526homo_sapiensENSP0000038169840.051729.7158stegastes_partitusENSSPAP0000002900547.987635.6037
ENSG00000179526homo_sapiensENSP0000038169815.24559.30233oncorhynchus_tshawytschaENSOTSP0000504298916.809110.2564
ENSG00000179526homo_sapiensENSP0000038169829.19919.3798oncorhynchus_tshawytschaENSOTSP0000500994619.894413.2042
ENSG00000179526homo_sapiensENSP0000038169825.581420.9302oncorhynchus_tshawytschaENSOTSP0000509520322.44918.3673
ENSG00000179526homo_sapiensENSP0000038169825.581420.9302oncorhynchus_tshawytschaENSOTSP0000509410622.44918.3673
ENSG00000179526homo_sapiensENSP0000038169850.387638.7597oncorhynchus_tshawytschaENSOTSP0000505631727.464821.1268
ENSG00000179526homo_sapiensENSP0000038169850.387638.7597oncorhynchus_tshawytschaENSOTSP0000501704927.464821.1268
ENSG00000179526homo_sapiensENSP0000038169850.64639.7933oncorhynchus_tshawytschaENSOTSP0000509556344.545535
ENSG00000179526homo_sapiensENSP0000038169829.974220.155acanthochromis_polyacanthusENSAPOP0000003312322.350715.0289
ENSG00000179526homo_sapiensENSP0000038169850.129238.5013acanthochromis_polyacanthusENSAPOP0000003423644.393634.0961
ENSG00000179526homo_sapiensENSP0000038169849.612439.0181acanthochromis_polyacanthusENSAPOP0000003386727.080421.2976
ENSG00000179526homo_sapiensENSP0000038169854.52239.7933aquila_chrysaetos_chrysaetosENSACCP0002000476530.18622.0315
ENSG00000179526homo_sapiensENSP0000038169829.974219.8966nothobranchius_furzeriENSNFUP0001504931722.612115.0097
ENSG00000179526homo_sapiensENSP0000038169848.578836.4341nothobranchius_furzeriENSNFUP0001503650026.780620.0855
ENSG00000179526homo_sapiensENSP0000038169831.007821.9638cyprinodon_variegatusENSCVAP0000002093223.255816.4729
ENSG00000179526homo_sapiensENSP0000038169847.286834.8837cyprinodon_variegatusENSCVAP0000002332842.06931.0345
ENSG00000179526homo_sapiensENSP0000038169849.095634.8837cyprinodon_variegatusENSCVAP0000002370626.874119.0948
ENSG00000179526homo_sapiensENSP0000038169828.682220.4134denticeps_clupeoidesENSDCDP0000005647121.807515.5206
ENSG00000179526homo_sapiensENSP0000038169849.095636.6925denticeps_clupeoidesENSDCDP0000004346826.798320.0282
ENSG00000179526homo_sapiensENSP0000038169848.320437.7261denticeps_clupeoidesENSDCDP0000001739145.833335.7843
ENSG00000179526homo_sapiensENSP0000038169832.299722.739larimichthys_croceaENSLCRP0000506004622.727316
ENSG00000179526homo_sapiensENSP0000038169850.64638.7597larimichthys_croceaENSLCRP0000504146944.343933.9367
ENSG00000179526homo_sapiensENSP0000038169849.35438.5013larimichthys_croceaENSLCRP0000503582126.977421.0452
ENSG00000179526homo_sapiensENSP0000038169832.041320.9302takifugu_rubripesENSTRUP0000002967123.984515.6673
ENSG00000179526homo_sapiensENSP0000038169849.612436.6925takifugu_rubripesENSTRUP0000007975827.042320
ENSG00000179526homo_sapiensENSP0000038169851.93840.0517takifugu_rubripesENSTRUP0000005997640.770831.4402
ENSG00000179526homo_sapiensENSP0000038169829.457420.6718hippocampus_comesENSHCOP0000001117522.61915.873
ENSG00000179526homo_sapiensENSP0000038169847.028435.1421hippocampus_comesENSHCOP0000002368026.804120.0295
ENSG00000179526homo_sapiensENSP0000038169849.095637.4677hippocampus_comesENSHCOP0000001523938.775529.5918
ENSG00000179526homo_sapiensENSP0000038169828.165418.863cyprinus_carpio_carpioENSCCRP0000007233821.49914.3984
ENSG00000179526homo_sapiensENSP0000038169827.90719.1214cyprinus_carpio_carpioENSCCRP0000007242521.218114.5383
ENSG00000179526homo_sapiensENSP0000038169849.095635.9173cyprinus_carpio_carpioENSCCRP0000000693826.760619.5775
ENSG00000179526homo_sapiensENSP0000038169849.612436.4341cyprinus_carpio_carpioENSCCRP0000006345326.815619.6927
ENSG00000179526homo_sapiensENSP0000038169844.702835.6589cyprinus_carpio_carpioENSCCRP0000013703941.686733.253
ENSG00000179526homo_sapiensENSP000003816989.560727.23514coturnix_japonicaENSCJPP0000500245111.17828.45921
ENSG00000179526homo_sapiensENSP0000038169825.064620.6718coturnix_japonicaENSCJPP0000500244939.271332.3887
ENSG00000179526homo_sapiensENSP0000038169830.232620.6718poecilia_latipinnaENSPLAP0000000226422.851615.625
ENSG00000179526homo_sapiensENSP0000038169849.612436.9509poecilia_latipinnaENSPLAP0000001640127.23420.2837
ENSG00000179526homo_sapiensENSP0000038169847.545235.1421poecilia_latipinnaENSPLAP0000001489442.298931.2644
ENSG00000179526homo_sapiensENSP0000038169826.873418.3463sinocyclocheilus_grahamiENSSGRP0000001653820.392213.9216
ENSG00000179526homo_sapiensENSP0000038169827.648619.1214sinocyclocheilus_grahamiENSSGRP0000004827521.529214.8893
ENSG00000179526homo_sapiensENSP0000038169848.837235.9173sinocyclocheilus_grahamiENSSGRP0000006474726.396619.4134
ENSG00000179526homo_sapiensENSP0000038169849.612436.4341sinocyclocheilus_grahamiENSSGRP0000009267026.815619.6927
ENSG00000179526homo_sapiensENSP0000038169830.232621.447maylandia_zebraENSMZEP0000500690122.543415.9923
ENSG00000179526homo_sapiensENSP0000038169849.095637.7261maylandia_zebraENSMZEP0000502850126.722920.5345
ENSG00000179526homo_sapiensENSP0000038169850.129238.2429maylandia_zebraENSMZEP0000503358744.495433.945
ENSG00000179526homo_sapiensENSP0000038169830.232619.8966tetraodon_nigroviridisENSTNIP0000001787223.168315.2475
ENSG00000179526homo_sapiensENSP0000038169849.612438.5013tetraodon_nigroviridisENSTNIP0000000441551.474539.9464
ENSG00000179526homo_sapiensENSP0000038169827.90721.447tetraodon_nigroviridisENSTNIP0000001097621.643316.6333
ENSG00000179526homo_sapiensENSP0000038169821.963814.9871tetraodon_nigroviridisENSTNIP0000000494240.094327.3585
ENSG00000179526homo_sapiensENSP0000038169831.782921.447paramormyrops_kingsleyaeENSPKIP0000003845123.076915.5722
ENSG00000179526homo_sapiensENSP0000038169851.162840.0517paramormyrops_kingsleyaeENSPKIP0000004194741.772232.7004
ENSG00000179526homo_sapiensENSP0000038169851.162839.7933paramormyrops_kingsleyaeENSPKIP0000002322627.653621.5084
ENSG00000179526homo_sapiensENSP0000038169830.749419.8966scleropages_formosusENSSFOP0001505814322.495314.5558
ENSG00000179526homo_sapiensENSP0000038169850.129239.7933scleropages_formosusENSSFOP0001504211840.416732.0833
ENSG00000179526homo_sapiensENSP0000038169852.713240.0517scleropages_formosusENSSFOP0001502198629.059822.0798
ENSG00000179526homo_sapiensENSP0000038169848.320432.5581leptobrachium_leishanenseENSLLEP0000002537526.600317.9232
ENSG00000179526homo_sapiensENSP0000038169827.648617.5711scophthalmus_maximusENSSMAP0000001831622.431914.2558
ENSG00000179526homo_sapiensENSP0000038169850.129238.5013scophthalmus_maximusENSSMAP0000002954027.132920.8392
ENSG00000179526homo_sapiensENSP0000038169831.266121.7054oryzias_melastigmaENSOMEP0000003179123.224616.1228
ENSG00000179526homo_sapiensENSP0000038169849.095636.6925oryzias_melastigmaENSOMEP0000001143225.956319.3989
ENSG00000179526homo_sapiensENSP0000038169843.152533.5917oryzias_melastigmaENSOMEP0000002484445.135135.1351

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0004842enables ubiquitin-protein transferase activity1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0007005involved_in mitochondrion organization1IEAHomo_sapiens(9606)Process
GO:0010803involved_in regulation of tumor necrosis factor-mediated signaling pathway1IDAHomo_sapiens(9606)Process
GO:0030262involved_in apoptotic nuclear changes1IEAHomo_sapiens(9606)Process
GO:0030425located_in dendrite1IEAHomo_sapiens(9606)Component
GO:0031424involved_in keratinization1IEAHomo_sapiens(9606)Process
GO:0031593enables polyubiquitin modification-dependent protein binding1IDAHomo_sapiens(9606)Function
GO:0042742involved_in defense response to bacterium1IDAHomo_sapiens(9606)Process
GO:0042802enables identical protein binding1IEAHomo_sapiens(9606)Function
GO:0043123involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling2IBA,IDAHomo_sapiens(9606)Process
GO:0043130enables ubiquitin binding1IBAHomo_sapiens(9606)Function
GO:0043161involved_in proteasome-mediated ubiquitin-dependent protein catabolic process1IBAHomo_sapiens(9606)Process
GO:0044877enables protein-containing complex binding1IEAHomo_sapiens(9606)Function
GO:0045202located_in synapse1IEAHomo_sapiens(9606)Component
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function
GO:0050728involved_in negative regulation of inflammatory response1ISSHomo_sapiens(9606)Process
GO:0071797part_of LUBAC complex3IBA,IDA,IPIHomo_sapiens(9606)Component
GO:0097039involved_in protein linear polyubiquitination2IBA,IDAHomo_sapiens(9606)Process
GO:2000348involved_in regulation of CD40 signaling pathway1IDAHomo_sapiens(9606)Process

Expression