Ensembl ID ENSG00000179526 Gene ID 81858 Accession 25321
Gene Symbol SHARPIN Alias SIPL1 Full Name SHANK associated RH domain interactor
Position 8 : 144098633 - 144104237 Length 5605 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary Enables polyubiquitin modification-dependent protein binding activity. Involved in protein linear polyubiquitination and regulation of signal transduction. Located in cytosol. Part of LUBAC complex. [provided by Alliance of Genome Resources, Apr 2022]

ENSG00000179526 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000179526 SHARPIN 0.58 9.15e-14 KIRC
ENSG00000179526 SHARPIN 1.00 7.59e-40 BRCA
ENSG00000179526 SHARPIN 1.02 1.69e-13 KICH
ENSG00000179526 SHARPIN 0.95 5.02e-16 LIHC
ENSG00000179526 SHARPIN 0.77 9.75e-11 UCEC
ENSG00000179526 SHARPIN 0.70 2.05e-13 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000179526 SHARPIN tumor 20179993
ENSG00000179526 SHARPIN tumor 20458142
ENSG00000179526 SHARPIN tumour 21455181
ENSG00000179526 SHARPIN cancer 21947080
ENSG00000179526 SHARPIN tumor 24506958
ENSG00000179526 SHARPIN prostate cancer 24925528
ENSG00000179526 SHARPIN prostate cancer 25550157
ENSG00000179526 SHARPIN Breast Cancer 25992689
ENSG00000179526 SHARPIN tumor 26506596
ENSG00000179526 SHARPIN cancer 26600301
ENSG00000179526 SHARPIN tumour 26931177
ENSG00000179526 SHARPIN breast cancer 27792127
ENSG00000179526 SHARPIN tumor 27941932
ENSG00000179526 SHARPIN cancer 27974362
ENSG00000179526 SHARPIN Breast Cancer 28063307
ENSG00000179526 SHARPIN prostate cancer 28221687
ENSG00000179526 SHARPIN ovarian cancer 28230260
ENSG00000179526 SHARPIN breast cancer 28879097
ENSG00000179526 SHARPIN lung cancer 28903384
ENSG00000179526 SHARPIN breast cancer 29100376
ENSG00000179526 SHARPIN cancers 29227283
ENSG00000179526 SHARPIN breast cancer 29248549
ENSG00000179526 SHARPIN breast tumors 29763465
ENSG00000179526 SHARPIN breast cancer 30148069
ENSG00000179526 SHARPIN tumors 30546455
ENSG00000179526 SHARPIN tumor 30850498
ENSG00000179526 SHARPIN nonmelanoma skin cancer 30936956
ENSG00000179526 SHARPIN tumors 31401046
ENSG00000179526 SHARPIN tumors 31461795
ENSG00000179526 SHARPIN breast cancer 31518875
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000179526 SHARPIN SARC 0.048 high
ENSG00000179526 SHARPIN STAD 0.035 low
ENSG00000179526 SHARPIN UVM 0.0046 high
ENSG00000179526 SHARPIN PAAD 0.046 high
ENSG00000179526 SHARPIN LGG 0.043 low
ENSG00000179526 SHARPIN READ 0.042 high
ENSG00000179526 SHARPIN THYM 0.016 low
ENSG00000179526 SHARPIN BRCA 0.037 low
ENSG00000179526 SHARPIN COAD 0.019 high
ENSG00000179526 SHARPIN UCS 0.024 high
ENSG00000179526 SHARPIN ESCA 0.026 low
ENSG00000179526 SHARPIN OV 0.006 low
ENSG00000179526 SHARPIN PRAD 0.0075 low
ENSG00000179526 SHARPIN BLCA 0.035 low
ENSG00000179526 SHARPIN LAML 0.013 high
ENSG00000179526 SHARPIN GBM 0.0091 high
ENSG00000179526 SHARPIN SKCM 0.00078 high
ENSG00000179526 SHARPIN CESC 0.027 high
ENSG00000179526 SHARPIN LIHC 0.0024 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000179526 SHARPIN LUSC Amp 7.893654 0.361888 0.580329 0.660679
ENSG00000179526 SHARPIN LUAD Amp 5.893053 0.217474 0.620329 0.569767
ENSG00000179526 SHARPIN LGG Amp 10.971340 0.160031 0.701236 0.177388
ENSG00000179526 SHARPIN LGG Del 1.685039 0.049384 0.554899 0.052632
ENSG00000179526 SHARPIN CESC Amp 2.979236 0.211316 0.634779 0.406780
ENSG00000179526 SHARPIN READ Amp 3.821167 0.262633 0.834453 0.624242
ENSG00000179526 SHARPIN COAD Amp 5.805710 0.153305 0.773983 0.556541
ENSG00000179526 SHARPIN PAAD Amp 2.554263 0.142787 0.442016 0.358696
ENSG00000179526 SHARPIN ESCA Amp 4.615119 0.459903 0.698802 0.663043
ENSG00000179526 SHARPIN SKCM Amp 4.353501 0.226150 0.772184 0.523161
ENSG00000179526 SHARPIN HNSC Amp 10.114269 0.279473 0.608046 0.720307
ENSG00000179526 SHARPIN LIHC Amp 17.883832 0.395842 1.181105 0.597297
ENSG00000179526 SHARPIN DLBC Amp 1.416472 0.258396 0.609102 0.291667
ENSG00000179526 SHARPIN BLCA Amp 2.752051 0.232125 0.583150 0.585784
ENSG00000179526 SHARPIN BRCA Amp 32.279236 0.436791 1.002267 0.571296
ENSG00000179526 SHARPIN STAD Amp 3.622314 0.208292 0.585365 0.634921
ENSG00000179526 SHARPIN PRAD Amp 1.261535 0.053984 0.694419 0.274390
ENSG00000179526 SHARPIN UCEC Amp 1.754975 0.127896 0.731315 0.339518
ENSG00000179526 SHARPIN UVM Amp 11.732583 0.660526 1.518657 0.762500
ENSG00000179526 SHARPIN OV Amp 103.864949 1.525542 1.235346 0.754750