Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerSARS-COV-OC43SARS-COV-2
Drug N.A.
Main interacting RNAs ncRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq DataSet_01_383 DataSet_01_86 DataSet_02_37 DataSet_02_38 DataSet_02_39

Description

Ensembl ID ENSG00000174720 Gene ID 51574 Accession 24912
Symbol LARP7 Alias ALAZS;PIP7S;hLARP7;HDCMA18P Full Name La ribonucleoprotein 7, transcriptional regulator
Status Confidence Length 20589 bases Strand Plus strand
Position 4 : 112637107 - 112657695 RNA binding domain RRM_3 , RRM_1 , La
Summary This gene encodes a protein which is found in the 7SK snRNP (small nuclear ribonucleoprotein). This snRNP complex inhibits a cyclin-dependent kinase, positive transcription elongation factor b, which is required for paused RNA polymerase II at a promoter to begin transcription elongation. A pseudogene of this gene is located on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000508585 RRM_1 PF00076 9.1e-18 1
ENSP00000508585 RRM_3 PF08777 1.8e-29 2
ENSP00000509527 RRM_1 PF00076 9.1e-18 1
ENSP00000509527 RRM_3 PF08777 1.8e-29 2
ENSP00000511571 RRM_1 PF00076 1.3e-17 1
ENSP00000511571 RRM_3 PF08777 2.3e-29 2
ENSP00000511571 La PF05383 2.7e-21 3
ENSP00000511577 RRM_1 PF00076 1.3e-17 1
ENSP00000511577 RRM_3 PF08777 2.3e-29 2
ENSP00000511577 La PF05383 2.7e-21 3
ENSP00000511578 RRM_1 PF00076 1.3e-17 1
ENSP00000511578 RRM_3 PF08777 2.3e-29 2
ENSP00000511578 La PF05383 2.7e-21 3
ENSP00000426376 RRM_1 PF00076 1.3e-17 1
ENSP00000426376 RRM_3 PF08777 2.3e-29 2
ENSP00000426376 La PF05383 2.8e-21 3
ENSP00000511573 RRM_1 PF00076 1.3e-17 1
ENSP00000511573 RRM_3 PF08777 2.3e-29 2
ENSP00000511573 La PF05383 2.7e-21 3
ENSP00000344950 RRM_1 PF00076 1.3e-17 1
ENSP00000344950 RRM_3 PF08777 2.3e-29 2
ENSP00000344950 La PF05383 2.7e-21 3
ENSP00000421541 RRM_1 PF00076 1.3e-17 1
ENSP00000421541 RRM_3 PF08777 2.3e-29 2
ENSP00000421541 La PF05383 2.7e-21 3
ENSP00000422626 RRM_1 PF00076 1.3e-17 1
ENSP00000422626 RRM_3 PF08777 2.3e-29 2
ENSP00000422626 La PF05383 2.7e-21 3
ENSP00000499190 RRM_1 PF00076 1.3e-17 1
ENSP00000499190 RRM_3 PF08777 2.3e-29 2
ENSP00000499190 La PF05383 2.7e-21 3
ENSP00000511572 RRM_1 PF00076 1.3e-17 1
ENSP00000511572 RRM_3 PF08777 2.3e-29 2
ENSP00000511572 La PF05383 2.7e-21 3
ENSP00000511574 RRM_1 PF00076 1.4e-17 1
ENSP00000511574 RRM_3 PF08777 2.3e-29 2
ENSP00000511574 La PF05383 2.8e-21 3
ENSP00000511576 RRM_1 PF00076 1.4e-17 1
ENSP00000511576 RRM_3 PF08777 2.4e-29 2
ENSP00000511576 La PF05383 2.8e-21 3
ENSP00000511575 RRM_1 PF00076 1.6e-16 1
ENSP00000511575 La PF05383 1.5e-21 2
ENSP00000509975 RRM_1 PF00076 3e-16 1
ENSP00000509975 La PF05383 2.1e-21 2
ENSP00000509899 RRM_1 PF00076 3.1e-16 1
ENSP00000509899 La PF05383 2.2e-21 2
ENSP00000509993 RRM_1 PF00076 4.2e-16 1
ENSP00000509993 La PF05383 1.9e-21 2
ENSP00000426646 La PF05383 4.1e-22 1
ENSP00000426709 La PF05383 5.6e-09 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
29422501 LARP7 family proteins have conserved function in telomerase assembly. C Laura Collopy 2018-02-08 Nature communications
19723344 P-TEFb- the final frontier. Jiri Kohoutek 2009-09-02 Cell division
26501340 The La-Related Proteins, a Family with Connections to Cancer. Chara Stavraka 2015-10-16 Biomolecules
32401147 Stabilize and connect: the role of LARP7 in nuclear non-coding RNA metabolism. Daniele Hasler 2021-02-01 RNA biology
27095572 Inhibition of PHLPP2/cyclin D1 protein translation contributes to the tumor suppressive effect of NFκB2 (p100). Jiawei Xu 2016-06-07 Oncotarget
33131423 Structure of S. pombe telomerase protein Pof8 C-terminal domain is an xRRM conserved among LARP7 proteins. Ritwika Basu 2021-08-01 RNA biology
37051324 Progress in 7SK ribonucleoprotein structural biology. B Momodou Camara 2023-01-01 Frontiers in molecular biosciences
29422503 LARP7-like protein Pof8 regulates telomerase assembly and poly(A)+TERRA expression in fission yeast. K Amanda Mennie 2018-02-08 Nature communications
34591954 The BRCA1/BARD1 ubiquitin ligase and its substrates. R Samuel Witus 2021-09-30 The Biochemical journal
35320752 Structural basis of RNA conformational switching in the transcriptional regulator 7SK RNP. Yuan Yang 2022-05-05 Molecular cell
22705372 Structural basis for telomerase RNA recognition and RNP assembly by the holoenzyme La family protein p65. Mahavir Singh 2012-07-13 Molecular cell
23471002 RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP. Lisa Muniz 2013-04-01 Nucleic acids research
29620212 LARP7 in papillary thyroid carcinoma induces NIS expression through suppression of the SHH signaling pathway. Xiaomei Sui 2018-06-01 Molecular medicine reports
22488152 LARP7 is a potential tumor suppressor gene in gastric cancer. Yulan Cheng 2012-07-01 Laboratory investigation; a journal of technical methods and pathology
33292040 The isolated La-module of LARP1 mediates 3' poly(A) protection and mRNA stabilization, dependent on its intrinsic PAM2 binding to PABPC1. Sandy Mattijssen 2021-02-01 RNA biology
25753663 Structural insight into the mechanism of stabilization of the 7SK small nuclear RNA by LARP7. Emiko Uchikawa 2015-03-31 Nucleic acids research
22379134 The Drosophila 7SK snRNP and the essential role of dHEXIM in development. Duy Nguyen 2012-07-01 Nucleic acids research
28782243 The La and related RNA-binding proteins (LARPs): structures, functions, and evolving perspectives. J Richard Maraia 2017-11-01 Wiley interdisciplinary reviews. RNA

Transcripts

Name Transcript ID bp Protein Translation ID
LARP7-223 ENST00000692075 2339 No protein -
LARP7-213 ENST00000512589 2109 101aa ENSP00000426709
LARP7-222 ENST00000690008 2525 45aa ENSP00000508938
LARP7-228 ENST00000694891 2101 581aa ENSP00000511571
LARP7-209 ENST00000509061 2332 582aa ENSP00000422626
LARP7-210 ENST00000509622 2020 45aa ENSP00000422451
LARP7-212 ENST00000512361 2670 No protein -
LARP7-221 ENST00000689844 1981 406aa ENSP00000509899
LARP7-201 ENST00000344442 2107 582aa ENSP00000344950
LARP7-225 ENST00000692416 1963 503aa ENSP00000509527
LARP7-211 ENST00000511529 1954 594aa ENSP00000426376
LARP7-208 ENST00000508577 579 119aa ENSP00000426646
LARP7-214 ENST00000513553 528 155aa ENSP00000422013
LARP7-204 ENST00000504079 424 No protein -
LARP7-205 ENST00000505034 2164 582aa ENSP00000421541
LARP7-229 ENST00000694892 1005 No protein -
LARP7-230 ENST00000694893 933 No protein -
LARP7-224 ENST00000692168 2148 No protein -
LARP7-231 ENST00000694894 3145 582aa ENSP00000511572
LARP7-227 ENST00000693442 1656 393aa ENSP00000509975
LARP7-216 ENST00000684864 2075 478aa ENSP00000509993
LARP7-232 ENST00000694895 2063 581aa ENSP00000511573
LARP7-226 ENST00000693375 1864 503aa ENSP00000508585
LARP7-220 ENST00000689262 3081 No protein -
LARP7-233 ENST00000694896 3169 594aa ENSP00000511574
LARP7-234 ENST00000694897 3204 223aa ENSP00000511575
LARP7-235 ENST00000694898 3172 595aa ENSP00000511576
LARP7-236 ENST00000694899 3130 581aa ENSP00000511577
LARP7-237 ENST00000694900 3127 580aa ENSP00000511578
LARP7-206 ENST00000505216 2095 45aa ENSP00000424116
LARP7-215 ENST00000651579 2076 582aa ENSP00000499190
LARP7-238 ENST00000694901 2288 45aa ENSP00000511579
LARP7-207 ENST00000507443 753 No protein -
LARP7-239 ENST00000694902 1185 No protein -
LARP7-219 ENST00000688617 2258 No protein -
LARP7-202 ENST00000503316 278 No protein -
LARP7-218 ENST00000685716 1429 No protein -
LARP7-217 ENST00000685424 1472 No protein -
LARP7-203 ENST00000503898 494 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000174720homo_sapiensENSP0000042858915.87597.20803homo_sapiensENSP0000034495029.896913.5739
ENSG00000174720homo_sapiensENSP0000026095645.588226.4706homo_sapiensENSP0000034495031.958818.5567
ENSG00000174720homo_sapiensENSP0000032612822.899711.9241homo_sapiensENSP0000034495029.037815.1203
ENSG00000174720homo_sapiensENSP0000029921332.993917.9226homo_sapiensENSP0000034495027.835115.1203
ENSG00000174720homo_sapiensENSP0000032199717.94318.20569homo_sapiensENSP0000034495028.178712.8866
ENSG00000174720homo_sapiensENSP0000038149022.237611.6022homo_sapiensENSP0000034495027.663214.433

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000174720homo_sapiensENSP0000034495099.140998.11nomascus_leucogenysENSNLEP0000001987498.129297.1088
ENSG00000174720homo_sapiensENSP0000034495099.656499.3127pan_paniscusENSPPAP0000003095498.639598.2993
ENSG00000174720homo_sapiensENSP0000034495099.484598.9691pongo_abeliiENSPPYP0000001676398.302297.7929
ENSG00000174720homo_sapiensENSP0000034495099.828299.3127pan_troglodytesENSPTRP0000007911698.641898.1324
ENSG00000174720homo_sapiensENSP0000034495099.828299.4845gorilla_gorillaENSGGOP0000004441598.641898.3022
ENSG00000174720homo_sapiensENSP0000034495087.113485.9107gorilla_gorillaENSGGOP0000004444995.121993.8086
ENSG00000174720homo_sapiensENSP0000034495086.254378.0069ornithorhynchus_anatinusENSOANP0000001479583.806375.793
ENSG00000174720homo_sapiensENSP0000034495086.941677.6632sarcophilus_harrisiiENSSHAP0000000942485.617676.4805
ENSG00000174720homo_sapiensENSP0000034495074.742366.323notamacropus_eugeniiENSMEUP0000000433786.653476.8924
ENSG00000174720homo_sapiensENSP0000034495076.116870.1031choloepus_hoffmanniENSCHOP0000000793083.742977.1267
ENSG00000174720homo_sapiensENSP0000034495092.26885.9107choloepus_hoffmanniENSCHOP0000000211093.881187.4126
ENSG00000174720homo_sapiensENSP0000034495092.955388.3162dasypus_novemcinctusENSDNOP0000001066392.795988.1647
ENSG00000174720homo_sapiensENSP0000034495085.395280.4124erinaceus_europaeusENSEEUP0000001167991.360386.0294
ENSG00000174720homo_sapiensENSP0000034495088.316282.646echinops_telfairiENSETEP0000000948690.973485.1327
ENSG00000174720homo_sapiensENSP0000034495098.1195.8763callithrix_jacchusENSCJAP0000000673997.941795.7118
ENSG00000174720homo_sapiensENSP0000034495098.625497.9381cercocebus_atysENSCATP0000004172998.795298.1067
ENSG00000174720homo_sapiensENSP0000034495098.453697.7663macaca_fascicularisENSMFAP0000000118998.623197.9346
ENSG00000174720homo_sapiensENSP0000034495098.453697.7663macaca_mulattaENSMMUP0000006955398.623197.9346
ENSG00000174720homo_sapiensENSP0000034495098.453697.9381macaca_nemestrinaENSMNEP0000002216698.623198.1067
ENSG00000174720homo_sapiensENSP0000034495098.797298.2818papio_anubisENSPANP0000000481797.623197.1138
ENSG00000174720homo_sapiensENSP0000034495098.625498.11mandrillus_leucophaeusENSMLEP0000000621998.795298.2788
ENSG00000174720homo_sapiensENSP0000034495082.64678.3505tursiops_truncatusENSTTRP0000000493792.678287.8613
ENSG00000174720homo_sapiensENSP0000034495092.955389.1753vulpes_vulpesENSVVUP0000000291593.43789.6373
ENSG00000174720homo_sapiensENSP0000034495089.003482.1306mus_spretusMGP_SPRETEiJ_P006282290.401483.4206
ENSG00000174720homo_sapiensENSP0000034495093.29988.6598equus_asinusENSEASP0000500767093.138988.5077
ENSG00000174720homo_sapiensENSP0000034495092.955387.1134capra_hircusENSCHIP0000001241593.43787.5648
ENSG00000174720homo_sapiensENSP0000034495077.147870.9622capra_hircusENSCHIP0000001206088.560281.4596
ENSG00000174720homo_sapiensENSP0000034495092.955387.9725loxodonta_africanaENSLAFP0000001322393.598688.5813
ENSG00000174720homo_sapiensENSP0000034495093.642690.0344panthera_leoENSPLOP0000003117193.642690.0344
ENSG00000174720homo_sapiensENSP0000034495093.29990.378ailuropoda_melanoleucaENSAMEP0000001651093.459590.5336
ENSG00000174720homo_sapiensENSP0000034495092.26886.7698bos_indicus_hybridENSBIXP0000502406892.906687.3702
ENSG00000174720homo_sapiensENSP0000034495093.29987.8007oryctolagus_cuniculusENSOCUP0000000611893.782488.2556
ENSG00000174720homo_sapiensENSP0000034495090.721685.3952equus_caballusENSECAP0000000138789.340184.0948
ENSG00000174720homo_sapiensENSP0000034495093.29989.3471canis_lupus_familiarisENSCAFP0084502393693.620789.6552
ENSG00000174720homo_sapiensENSP0000034495093.642690.0344panthera_pardusENSPPRP0000000268793.642690.0344
ENSG00000174720homo_sapiensENSP0000034495092.26888.488marmota_marmota_marmotaENSMMMP0000001266194.210590.3509
ENSG00000174720homo_sapiensENSP0000034495058.591154.6392balaenoptera_musculusENSBMSP0001001584690.933384.8
ENSG00000174720homo_sapiensENSP0000034495088.144382.4742cavia_porcellusENSCPOP0000001064190.476284.6561
ENSG00000174720homo_sapiensENSP0000034495093.470889.8625felis_catusENSFCAP0000002618493.470889.8625
ENSG00000174720homo_sapiensENSP0000034495092.955389.3471ursus_americanusENSUAMP0000000127593.115389.5009
ENSG00000174720homo_sapiensENSP0000034495087.972578.866monodelphis_domesticaENSMODP0000000702485.049876.2458
ENSG00000174720homo_sapiensENSP0000034495092.611786.9416bison_bison_bisonENSBBBP0000000271193.091587.3921
ENSG00000174720homo_sapiensENSP0000034495092.439987.8007monodon_monocerosENSMMNP0001501354992.758688.1034
ENSG00000174720homo_sapiensENSP0000034495092.439988.488sus_scrofaENSSSCP0000008133092.59988.6403
ENSG00000174720homo_sapiensENSP0000034495094.845491.7526microcebus_murinusENSMICP0000004642994.35991.2821
ENSG00000174720homo_sapiensENSP0000034495087.113481.4433octodon_degusENSODEP0000001507090.860284.9462
ENSG00000174720homo_sapiensENSP0000034495090.549885.0515jaculus_jaculusENSJJAP0000000030491.493185.9375
ENSG00000174720homo_sapiensENSP0000034495023.195920.2749ovis_aries_rambouilletENSOARP0002001160087.662376.6234
ENSG00000174720homo_sapiensENSP0000034495091.924487.9725ursus_maritimusENSUMAP0000000254791.766787.8216
ENSG00000174720homo_sapiensENSP0000034495070.790466.1512ochotona_princepsENSOPRP0000000878173.179468.3837
ENSG00000174720homo_sapiensENSP0000034495092.611787.9725delphinapterus_leucasENSDLEP0000002437993.091588.4283
ENSG00000174720homo_sapiensENSP0000034495093.642689.1753physeter_catodonENSPCTP0000500526486.097981.9905
ENSG00000174720homo_sapiensENSP0000034495088.48881.6151mus_caroliMGP_CAROLIEiJ_P006042190.350983.3333
ENSG00000174720homo_sapiensENSP0000034495088.48881.4433mus_musculusENSMUSP0000002958890.350983.1579
ENSG00000174720homo_sapiensENSP0000034495037.113433.1615mus_musculusENSMUSP0000012221285.039475.9843
ENSG00000174720homo_sapiensENSP0000034495089.175385.2234dipodomys_ordiiENSDORP0000002030589.94885.9619
ENSG00000174720homo_sapiensENSP0000034495092.439988.8316mustela_putorius_furoENSMPUP0000000826893.079689.4464
ENSG00000174720homo_sapiensENSP0000034495082.64678.5223mustela_putorius_furoENSMPUP0000001794193.762289.0838
ENSG00000174720homo_sapiensENSP0000034495083.161577.3196aotus_nancymaaeENSANAP0000000861091.493485.0662
ENSG00000174720homo_sapiensENSP0000034495096.735494.1581aotus_nancymaaeENSANAP0000002685698.083695.4704
ENSG00000174720homo_sapiensENSP0000034495075.257770.7904saimiri_boliviensis_boliviensisENSSBOP0000001174489.754184.4262
ENSG00000174720homo_sapiensENSP0000034495097.766395.3608saimiri_boliviensis_boliviensisENSSBOP0000002912797.598695.1973
ENSG00000174720homo_sapiensENSP0000034495093.986389.8625vicugna_pacosENSVPAP0000000977294.14890.0172
ENSG00000174720homo_sapiensENSP0000034495098.625497.7663chlorocebus_sabaeusENSCSAP0000000017698.795297.9346
ENSG00000174720homo_sapiensENSP0000034495087.800780.756tupaia_belangeriENSTBEP0000000796988.561581.4558
ENSG00000174720homo_sapiensENSP0000034495074.398669.244mesocricetus_auratusENSMAUP0000000444587.122781.0865
ENSG00000174720homo_sapiensENSP0000034495092.783587.8007phocoena_sinusENSPSNP0000000576292.943287.9518
ENSG00000174720homo_sapiensENSP0000034495094.158189.8625camelus_dromedariusENSCDRP0000501075194.320190.0172
ENSG00000174720homo_sapiensENSP0000034495082.989775.945carlito_syrichtaENSTSYP0000003384888.299880.8044
ENSG00000174720homo_sapiensENSP0000034495087.972584.1924carlito_syrichtaENSTSYP0000000621594.29190.2394
ENSG00000174720homo_sapiensENSP0000034495090.034485.9107panthera_tigris_altaicaENSPTIP0000002532590.972286.8056
ENSG00000174720homo_sapiensENSP0000034495088.48881.2715rattus_norvegicusENSRNOP0000006535785.976678.9649
ENSG00000174720homo_sapiensENSP0000034495095.017291.2371prolemur_simusENSPSMP0000000458294.691890.9247
ENSG00000174720homo_sapiensENSP0000034495076.460570.2749microtus_ochrogasterENSMOCP0000001703888.293681.1508
ENSG00000174720homo_sapiensENSP0000034495089.347182.8179microtus_ochrogasterENSMOCP0000001241390.592383.9721
ENSG00000174720homo_sapiensENSP0000034495043.986339.8625sorex_araneusENSSARP0000000017584.210576.3158
ENSG00000174720homo_sapiensENSP0000034495088.48882.1306peromyscus_maniculatus_bairdiiENSPEMP0000001409590.350983.8596
ENSG00000174720homo_sapiensENSP0000034495092.096286.4261bos_mutusENSBMUP0000002833193.217487.4783
ENSG00000174720homo_sapiensENSP0000034495088.831681.6151mus_spicilegusENSMSIP0000003365590.384683.042
ENSG00000174720homo_sapiensENSP0000034495072.336866.323cricetulus_griseus_chok1gshdENSCGRP0000101099284.708377.666
ENSG00000174720homo_sapiensENSP0000034495088.831683.3333cricetulus_griseus_chok1gshdENSCGRP0000102830090.701885.0877
ENSG00000174720homo_sapiensENSP0000034495090.37884.7079pteropus_vampyrusENSPVAP0000000025890.533684.8537
ENSG00000174720homo_sapiensENSP0000034495073.711367.1821myotis_lucifugusENSMLUP0000001626185.458277.8884
ENSG00000174720homo_sapiensENSP0000034495088.144379.2096vombatus_ursinusENSVURP0001000714386.363677.6094
ENSG00000174720homo_sapiensENSP0000034495088.659882.646rhinolophus_ferrumequinumENSRFEP0001002662087.606181.6638
ENSG00000174720homo_sapiensENSP0000034495092.611788.8316neovison_visonENSNVIP0000001799993.091589.2919
ENSG00000174720homo_sapiensENSP0000034495092.26886.7698bos_taurusENSBTAP0000006184090.40485.0168
ENSG00000174720homo_sapiensENSP0000034495091.237186.0825heterocephalus_glaber_femaleENSHGLP0000005283892.027786.8284
ENSG00000174720homo_sapiensENSP0000034495083.848883.5052rhinopithecus_bietiENSRBIP0000001563596.633796.2376
ENSG00000174720homo_sapiensENSP0000034495093.127289.0034canis_lupus_dingoENSCAFP0002002179193.609789.4646
ENSG00000174720homo_sapiensENSP0000034495093.470890.0344sciurus_vulgarisENSSVLP0000503318492.832889.4198
ENSG00000174720homo_sapiensENSP0000034495079.725175.945sciurus_vulgarisENSSVLP0000502322590.62586.3281
ENSG00000174720homo_sapiensENSP0000034495087.800778.5223phascolarctos_cinereusENSPCIP0000002714578.85870.5247
ENSG00000174720homo_sapiensENSP0000034495053.608249.1409procavia_capensisENSPCAP0000000319262.457.2
ENSG00000174720homo_sapiensENSP0000034495088.831682.646nannospalax_galiliENSNGAP0000000526289.137982.931
ENSG00000174720homo_sapiensENSP0000034495092.611786.9416bos_grunniensENSBGRP0000000417893.091587.3921
ENSG00000174720homo_sapiensENSP0000034495089.347185.3952chinchilla_lanigeraENSCLAP0000000842191.549387.5
ENSG00000174720homo_sapiensENSP0000034495092.783587.1134cervus_hanglu_yarkandensisENSCHYP0000002439693.103487.4138
ENSG00000174720homo_sapiensENSP0000034495092.096287.1134catagonus_wagneriENSCWAP0000001508191.623986.6667
ENSG00000174720homo_sapiensENSP0000034495094.158189.8625ictidomys_tridecemlineatusENSSTOP0000001057494.97490.6413
ENSG00000174720homo_sapiensENSP0000034495095.360890.378otolemur_garnettiiENSOGAP0000000146795.034290.0685
ENSG00000174720homo_sapiensENSP0000034495086.941680.9278cebus_imitatorENSCCAP0000001162293.703787.2222
ENSG00000174720homo_sapiensENSP0000034495098.1196.3918cebus_imitatorENSCCAP0000001796297.941796.2264
ENSG00000174720homo_sapiensENSP0000034495092.439988.6598urocitellus_parryiiENSUPAP0001001798294.38690.5263
ENSG00000174720homo_sapiensENSP0000034495092.611787.1134moschus_moschiferusENSMMSP0000003257292.93187.4138
ENSG00000174720homo_sapiensENSP0000034495097.938197.5945rhinopithecus_roxellanaENSRROP0000001876198.106797.7625
ENSG00000174720homo_sapiensENSP0000034495088.48881.0997mus_pahariMGP_PahariEiJ_P007134490.192682.662
ENSG00000174720homo_sapiensENSP0000034495077.319674.5704propithecus_coquereliENSPCOP0000002360487.378684.2718
ENSG00000174720homo_sapiensENSP0000034495046.735427.6632drosophila_melanogasterFBpp029049045.714327.0588
ENSG00000174720homo_sapiensENSP0000034495044.329923.7113ciona_intestinalisENSCINP0000003121954.088128.9308
ENSG00000174720homo_sapiensENSP0000034495055.154636.0825petromyzon_marinusENSPMAP0000000591654.778235.8362
ENSG00000174720homo_sapiensENSP0000034495059.106540.7216eptatretus_burgeriENSEBUP0000002240959.106540.7216
ENSG00000174720homo_sapiensENSP0000034495075.085960.8247callorhinchus_miliiENSCMIP0000001548073.445459.4958
ENSG00000174720homo_sapiensENSP0000034495076.460563.7457latimeria_chalumnaeENSLACP0000001561073.432361.2211
ENSG00000174720homo_sapiensENSP0000034495066.151250.1718lepisosteus_oculatusENSLOCP0000001426863.847448.4245
ENSG00000174720homo_sapiensENSP0000034495025.601421.4777clupea_harengusENSCHAP0000005607683.240269.8324
ENSG00000174720homo_sapiensENSP0000034495064.43350.8591clupea_harengusENSCHAP0000005606569.444454.8148
ENSG00000174720homo_sapiensENSP0000034495065.635752.4055danio_rerioENSDARP0000009250768.828854.955
ENSG00000174720homo_sapiensENSP0000034495014.776612.543carassius_auratusENSCARP0000008944383.495170.8738
ENSG00000174720homo_sapiensENSP0000034495036.426127.8351carassius_auratusENSCARP0000007049174.38656.8421
ENSG00000174720homo_sapiensENSP0000034495067.869454.2955astyanax_mexicanusENSAMXP0000000260969.911555.9292
ENSG00000174720homo_sapiensENSP0000034495069.072254.1237ictalurus_punctatusENSIPUP0000002944369.310354.3103
ENSG00000174720homo_sapiensENSP0000034495069.759553.6082esox_luciusENSELUP0000003611470.36454.0728
ENSG00000174720homo_sapiensENSP0000034495066.151251.0309electrophorus_electricusENSEEEP0000003891569.620353.7071
ENSG00000174720homo_sapiensENSP0000034495069.587654.6392oncorhynchus_kisutchENSOKIP0000502198468.760653.9898
ENSG00000174720homo_sapiensENSP0000034495012.02759.96564oncorhynchus_kisutchENSOKIP0000506365578.651765.1685
ENSG00000174720homo_sapiensENSP0000034495069.759554.4674oncorhynchus_mykissENSOMYP0000006438668.697153.6379
ENSG00000174720homo_sapiensENSP0000034495046.391835.0515oncorhynchus_mykissENSOMYP0000010795157.692343.5897
ENSG00000174720homo_sapiensENSP0000034495016.838511.512salmo_salarENSSSAP0000003227064.900744.3709
ENSG00000174720homo_sapiensENSP0000034495069.759554.1237salmo_salarENSSSAP0000013666569.165253.6627
ENSG00000174720homo_sapiensENSP0000034495015.807611.8557salmo_truttaENSSTUP0000010779082.142961.6071
ENSG00000174720homo_sapiensENSP0000034495069.759554.1237salmo_truttaENSSTUP0000007417069.165253.6627
ENSG00000174720homo_sapiensENSP0000034495019.072214.433salmo_truttaENSSTUP0000010777570.700653.5032
ENSG00000174720homo_sapiensENSP0000034495014.089310.6529gadus_morhuaENSGMOP0000006308649.397637.3494
ENSG00000174720homo_sapiensENSP0000034495043.814431.2715gadus_morhuaENSGMOP0000003409960.141542.9245
ENSG00000174720homo_sapiensENSP0000034495015.979412.543gadus_morhuaENSGMOP0000001492083.783865.7658
ENSG00000174720homo_sapiensENSP0000034495013.917510.4811gadus_morhuaENSGMOP0000005374748.795236.747
ENSG00000174720homo_sapiensENSP0000034495060.652948.2818fundulus_heteroclitusENSFHEP0000003412062.699849.9112
ENSG00000174720homo_sapiensENSP0000034495067.35452.7491poecilia_reticulataENSPREP000000288447054.8214
ENSG00000174720homo_sapiensENSP0000034495067.010353.0928xiphophorus_maculatusENSXMAP0000000850569.642955.1786
ENSG00000174720homo_sapiensENSP0000034495066.666750.8591oryzias_latipesENSORLP0000000627671.323554.4118
ENSG00000174720homo_sapiensENSP0000034495062.886649.4845cyclopterus_lumpusENSCLMP0000502271865.709251.7056
ENSG00000174720homo_sapiensENSP0000034495064.261250.8591oreochromis_niloticusENSONIP0000004145665.845152.1127
ENSG00000174720homo_sapiensENSP0000034495068.213153.9519haplochromis_burtoniENSHBUP0000003274670.766555.9715
ENSG00000174720homo_sapiensENSP0000034495068.041253.7801astatotilapia_callipteraENSACLP0000003423270.588255.7932
ENSG00000174720homo_sapiensENSP0000034495066.494853.2646sparus_aurataENSSAUP0001006739068.374654.7703
ENSG00000174720homo_sapiensENSP0000034495068.213155.6701lates_calcariferENSLCAP0001003649470.141357.2438
ENSG00000174720homo_sapiensENSP0000034495076.116862.3711xenopus_tropicalisENSXETP0000005199474.704961.2142
ENSG00000174720homo_sapiensENSP0000034495084.707975.2577chrysemys_picta_belliiENSCPBP0000000687483.136673.8617
ENSG00000174720homo_sapiensENSP0000034495083.333373.3677crocodylus_porosusENSCPRP0000500728673.820464.9924
ENSG00000174720homo_sapiensENSP0000034495076.632363.9175laticauda_laticaudataENSLLTP0000000698378.798665.7244
ENSG00000174720homo_sapiensENSP0000034495078.86666.1512notechis_scutatusENSNSUP0000000518179.549466.7244
ENSG00000174720homo_sapiensENSP0000034495080.240566.8385pseudonaja_textilisENSPTXP0000002534179.421866.1565
ENSG00000174720homo_sapiensENSP0000034495083.505273.5395anas_platyrhynchos_platyrhynchosENSAPLP0000001269881.680771.9328
ENSG00000174720homo_sapiensENSP0000034495081.786970.6186gallus_gallusENSGALP0001000547873.230863.2308
ENSG00000174720homo_sapiensENSP0000034495081.615171.4777meleagris_gallopavoENSMGAP0000001142383.922373.4982
ENSG00000174720homo_sapiensENSP0000034495083.161573.1959serinus_canariaENSSCAP0000001221982.033972.2034
ENSG00000174720homo_sapiensENSP0000034495078.350568.2131parus_majorENSPMJP0000000685080.994770.5151
ENSG00000174720homo_sapiensENSP0000034495081.443371.134anolis_carolinensisENSACAP0000001049677.073267.3171
ENSG00000174720homo_sapiensENSP0000034495031.786925.4296neolamprologus_brichardiENSNBRP000000102207459.2
ENSG00000174720homo_sapiensENSP0000034495013.058410.4811neolamprologus_brichardiENSNBRP0000001023882.608766.3043
ENSG00000174720homo_sapiensENSP0000034495078.522365.2921naja_najaENSNNAP0000000641779.065765.7439
ENSG00000174720homo_sapiensENSP0000034495082.302470.7904podarcis_muralisENSPMRP0000001468681.049169.7123
ENSG00000174720homo_sapiensENSP0000034495082.989773.1959geospiza_fortisENSGFOP0000001588481.864472.2034
ENSG00000174720homo_sapiensENSP0000034495083.333373.3677taeniopygia_guttataENSTGUP0000001945082.203472.3729
ENSG00000174720homo_sapiensENSP0000034495075.429659.622erpetoichthys_calabaricusENSECRP0000001524474.533158.9134
ENSG00000174720homo_sapiensENSP0000034495065.635751.5464kryptolebias_marmoratusENSKMAP0000000667568.953154.1516
ENSG00000174720homo_sapiensENSP0000034495079.896968.2131salvator_merianaeENSSMRP0000001972280.172468.4483
ENSG00000174720homo_sapiensENSP0000034495068.213152.4055oryzias_javanicusENSOJAP0000002532772.577755.7587
ENSG00000174720homo_sapiensENSP0000034495067.010351.3746amphilophus_citrinellusENSACIP0000003085572.490755.5762
ENSG00000174720homo_sapiensENSP0000034495067.869453.7801dicentrarchus_labraxENSDLAP0000505109665.074151.5651
ENSG00000174720homo_sapiensENSP0000034495067.697654.4674amphiprion_perculaENSAPEP0000003072669.611356.0071
ENSG00000174720homo_sapiensENSP0000034495067.182151.0309oryzias_sinensisENSOSIP0000003538071.743154.4954
ENSG00000174720homo_sapiensENSP0000034495084.364373.0241pelodiscus_sinensisENSPSIP0000001616382.52171.4286
ENSG00000174720homo_sapiensENSP0000034495084.879775.0859gopherus_evgoodeiENSGEVP0000501199881.518272.1122
ENSG00000174720homo_sapiensENSP0000034495084.707974.9141chelonoidis_abingdoniiENSCABP0000000547782.579673.0318
ENSG00000174720homo_sapiensENSP0000034495067.697654.2955seriola_dumeriliENSSDUP0000000960069.858256.0284
ENSG00000174720homo_sapiensENSP0000034495066.494852.2337cottoperca_gobioENSCGOP0000002659268.25453.6155
ENSG00000174720homo_sapiensENSP0000034495083.848874.055struthio_camelus_australisENSSCUP0000000151871.659363.2893
ENSG00000174720homo_sapiensENSP0000034495083.333373.1959anser_brachyrhynchusENSABRP0000002106582.623572.5724
ENSG00000174720homo_sapiensENSP0000034495066.666752.4055gasterosteus_aculeatusENSGACP0000002594067.713853.2286
ENSG00000174720homo_sapiensENSP0000034495068.728552.921cynoglossus_semilaevisENSCSEP0000001412070.796554.5133
ENSG00000174720homo_sapiensENSP0000034495066.838553.2646poecilia_formosaENSPFOP0000000027169.713355.5556
ENSG00000174720homo_sapiensENSP0000034495069.931355.1546myripristis_murdjanENSMMDP0000503317371.654956.5141
ENSG00000174720homo_sapiensENSP0000034495068.556753.7801sander_luciopercaENSSLUP0000005492270.494755.3004
ENSG00000174720homo_sapiensENSP0000034495083.67772.5086strigops_habroptilaENSSHBP0000502073082.124871.1636
ENSG00000174720homo_sapiensENSP0000034495067.869454.6392amphiprion_ocellarisENSAOCP0000001179769.78856.1837
ENSG00000174720homo_sapiensENSP0000034495081.786971.8213terrapene_carolina_triunguisENSTMTP0000000875581.646771.6981
ENSG00000174720homo_sapiensENSP0000034495069.759554.6392hucho_huchoENSHHUP0000006506268.120853.3557
ENSG00000174720homo_sapiensENSP000003449509.621997.38832hucho_huchoENSHHUP0000005481581.159462.3188
ENSG00000174720homo_sapiensENSP0000034495066.838553.2646betta_splendensENSBSLP0000003920570.216655.9567
ENSG00000174720homo_sapiensENSP0000034495067.35453.6082pygocentrus_nattereriENSPNAP0000001187269.135855.0265
ENSG00000174720homo_sapiensENSP0000034495067.697655.1546anabas_testudineusENSATEP0000002342668.048455.4404
ENSG00000174720homo_sapiensENSP0000034495015.635712.7148seriola_lalandi_dorsalisENSSLDP0000000641281.98266.6667
ENSG00000174720homo_sapiensENSP0000034495029.553325.0859seriola_lalandi_dorsalisENSSLDP0000000642877.477565.7658
ENSG00000174720homo_sapiensENSP0000034495030.75623.8832labrus_bergyltaENSLBEP0000002455477.826160.4348
ENSG00000174720homo_sapiensENSP0000034495067.182152.2337labrus_bergyltaENSLBEP0000002633268.118552.9617
ENSG00000174720homo_sapiensENSP0000034495013.230210.6529pundamilia_nyerereiENSPNYP0000003155082.795766.6667
ENSG00000174720homo_sapiensENSP0000034495031.958825.4296pundamilia_nyerereiENSPNYP0000003155274.459.2
ENSG00000174720homo_sapiensENSP0000034495068.041254.1237mastacembelus_armatusENSMAMP0000000860369.841355.5556
ENSG00000174720homo_sapiensENSP0000034495068.900354.811stegastes_partitusENSSPAP0000002130970.848156.3604
ENSG00000174720homo_sapiensENSP0000034495069.24453.9519oncorhynchus_tshawytschaENSOTSP0000510502768.421153.3107
ENSG00000174720homo_sapiensENSP0000034495042.611733.677oncorhynchus_tshawytschaENSOTSP0000500321461.386148.5149
ENSG00000174720homo_sapiensENSP0000034495068.213154.4674acanthochromis_polyacanthusENSAPOP0000001194170.141356.0071
ENSG00000174720homo_sapiensENSP0000034495084.364373.0241aquila_chrysaetos_chrysaetosENSACCP0002002155582.799371.6695
ENSG00000174720homo_sapiensENSP0000034495068.556753.2646nothobranchius_furzeriENSNFUP0001502266468.205152.9915
ENSG00000174720homo_sapiensENSP0000034495066.838553.4364cyprinodon_variegatusENSCVAP0000001418670.47156.3406
ENSG00000174720homo_sapiensENSP0000034495068.556754.6392denticeps_clupeoidesENSDCDP0000004872070.370456.0847
ENSG00000174720homo_sapiensENSP0000034495067.869454.4674larimichthys_croceaENSLCRP0000503108569.542355.8099
ENSG00000174720homo_sapiensENSP0000034495081.443371.3058ficedula_albicollisENSFALP0000000100777.832568.1445
ENSG00000174720homo_sapiensENSP0000034495063.745751.7182hippocampus_comesENSHCOP0000001202068.576755.6377
ENSG00000174720homo_sapiensENSP0000034495067.525852.7491cyprinus_carpio_carpioENSCCRP0000005254965.939651.5101
ENSG00000174720homo_sapiensENSP0000034495084.192473.3677coturnix_japonicaENSCJPP0000500734982.352971.7647
ENSG00000174720homo_sapiensENSP0000034495066.838553.2646poecilia_latipinnaENSPLAP0000000943069.713355.5556
ENSG00000174720homo_sapiensENSP0000034495067.869453.4364sinocyclocheilus_grahamiENSSGRP0000003345869.542354.7535
ENSG00000174720homo_sapiensENSP0000034495068.041253.7801maylandia_zebraENSMZEP0000500264270.588255.7932
ENSG00000174720homo_sapiensENSP0000034495060.309345.8763tetraodon_nigroviridisENSTNIP0000000998565.853750.0938
ENSG00000174720homo_sapiensENSP0000034495070.962255.6701paramormyrops_kingsleyaeENSPKIP0000000769671.206955.8621
ENSG00000174720homo_sapiensENSP0000034495070.618654.6392scleropages_formosusENSSFOP0001503012771.97955.6918
ENSG00000174720homo_sapiensENSP0000034495075.085961.512leptobrachium_leishanenseENSLLEP0000000600970.483957.7419
ENSG00000174720homo_sapiensENSP0000034495066.32352.0619scophthalmus_maximusENSSMAP0000001843267.013952.6042
ENSG00000174720homo_sapiensENSP0000034495067.697652.5773oryzias_melastigmaENSOMEP0000000588372.161256.044

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000122involved_in negative regulation of transcription by RNA polymerase II1IMPHomo_sapiens(9606)Process
GO:0000494involved_in box C/D RNA 3-end processing1IMPHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003729enables mRNA binding1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus2IBA,IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0005844part_of polysome1IBAHomo_sapiens(9606)Component
GO:0006397involved_in mRNA processing1IEAHomo_sapiens(9606)Process
GO:0007283involved_in spermatogenesis1ISSHomo_sapiens(9606)Process
GO:0008380involved_in RNA splicing1IEAHomo_sapiens(9606)Process
GO:0017070enables U6 snRNA binding1IDAHomo_sapiens(9606)Function
GO:0030154involved_in cell differentiation1IEAHomo_sapiens(9606)Process
GO:0032897involved_in negative regulation of viral transcription1IMPHomo_sapiens(9606)Process
GO:0034244involved_in negative regulation of transcription elongation by RNA polymerase II1ICHomo_sapiens(9606)Process
GO:0048024involved_in regulation of mRNA splicing, via spliceosome1IMPHomo_sapiens(9606)Process
GO:0097322enables 7SK snRNA binding1IDAHomo_sapiens(9606)Function
GO:0120259part_of 7SK snRNP1IDAHomo_sapiens(9606)Component
GO:1904871involved_in positive regulation of protein localization to Cajal body1IDAHomo_sapiens(9606)Process
GO:1905382involved_in positive regulation of snRNA transcription by RNA polymerase II1IDAHomo_sapiens(9606)Process
GO:1990438involved_in U6 2-O-snRNA methylation1IMPHomo_sapiens(9606)Process
GO:1990904part_of ribonucleoprotein complex1IDAHomo_sapiens(9606)Component

Expression