RBPWorld - a comprehensive database of RNA Binding Proteins

Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	CancerCHIKVSARS-COV-OC43FlavivirusesHIVIAVRVSARS-COV-2SINVDengueZika
Drug	N.A.
Main interacting RNAs	snRNA
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	DataSet_01_115 DataSet_01_368

Description

Ensembl ID	ENSG00000174231	Gene ID	10594	Accession	17340
Symbol	PRPF8	Alias	PRP8;RP13;HPRP8;PRPC8;SNRNP220	Full Name	pre-mRNA processing factor 8
Status	Confidence	Length	34239 bases	Strand	Minus strand
Position	17 : 1650629 - 1684867	RNA binding domain	PROCT , PRP8_domainIV , PRO8NT , U6-snRNA_bdg , PROCN , RRM_4 , U5_2-snRNA_bdg
Summary	Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000460849	RRM_4	PF10598	2.5e-47	1
ENSP00000460849	U5_2-snRNA_bdg	PF10597	1e-70	2
ENSP00000460849	U6-snRNA_bdg	PF10596	1.3e-88	3
ENSP00000460849	PROCT	PF08084	1.2e-51	4
ENSP00000460849	PROCN	PF08083	1.6e-233	5
ENSP00000460849	PRO8NT	PF08082	5e-85	6
ENSP00000460849	PRP8_domainIV	PF12134	1.1e-128	7
ENSP00000515362	RRM_4	PF10598	2.5e-47	1
ENSP00000515362	U5_2-snRNA_bdg	PF10597	2.4e-72	2
ENSP00000515362	U6-snRNA_bdg	PF10596	1.2e-88	3
ENSP00000515362	PROCT	PF08084	1.2e-51	4
ENSP00000515362	PROCN	PF08083	1.1e-233	5
ENSP00000515362	PRO8NT	PF08082	5e-85	6
ENSP00000515362	PRP8_domainIV	PF12134	1.1e-128	7
ENSP00000515363	RRM_4	PF10598	2.6e-47	1
ENSP00000515363	U5_2-snRNA_bdg	PF10597	2.4e-72	2
ENSP00000515363	U6-snRNA_bdg	PF10596	1.3e-88	3
ENSP00000515363	PROCT	PF08084	1.2e-51	4
ENSP00000515363	PROCN	PF08083	1.2e-192	5
ENSP00000515363	PROCN	PF08083	1.2e-192	6
ENSP00000515363	PRO8NT	PF08082	5e-85	7
ENSP00000515363	PRP8_domainIV	PF12134	1e-128	8
ENSP00000304350	RRM_4	PF10598	2.6e-47	1
ENSP00000304350	U5_2-snRNA_bdg	PF10597	2.5e-72	2
ENSP00000304350	U6-snRNA_bdg	PF10596	1.3e-88	3
ENSP00000304350	PROCT	PF08084	1.2e-51	4
ENSP00000304350	PROCN	PF08083	1.7e-233	5
ENSP00000304350	PRO8NT	PF08082	5.1e-85	6
ENSP00000304350	PRP8_domainIV	PF12134	1.1e-128	7
ENSP00000460348	RRM_4	PF10598	2.6e-47	1
ENSP00000460348	U5_2-snRNA_bdg	PF10597	2.5e-72	2
ENSP00000460348	U6-snRNA_bdg	PF10596	1.3e-88	3
ENSP00000460348	PROCT	PF08084	1.2e-51	4
ENSP00000460348	PROCN	PF08083	1.7e-233	5
ENSP00000460348	PRO8NT	PF08082	5.1e-85	6
ENSP00000460348	PRP8_domainIV	PF12134	1.1e-128	7
ENSP00000458151	RRM_4	PF10598	1e-42	1
ENSP00000458151	PROCN	PF08083	2.6e-234	2
ENSP00000458151	PRO8NT	PF08082	2.3e-42	3
ENSP00000458151	PRO8NT	PF08082	2.3e-42	4
ENSP00000515360	U6-snRNA_bdg	PF10596	4.2e-89	1
ENSP00000515360	PROCT	PF08084	4e-52	2
ENSP00000515360	PRP8_domainIV	PF12134	6.8e-109	3
ENSP00000515360	PRP8_domainIV	PF12134	6.8e-109	4
ENSP00000459095	PROCT	PF08084	6e-22	1

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal
24825008	Influenza viruses and mRNA splicing: doing more with less.	Julia Dubois	2014-05-13	mBio
31642809	Discovery proteomics in aging human skeletal muscle finds change in spliceosome, immunity, proteostasis and mitochondria.	Ceereena Ubaida-Mohien	2019-10-23	eLife
36609600	PRPF8 increases the aggressiveness of hepatocellular carcinoma by regulating FAK/AKT pathway via fibronectin 1 splicing.	L Juan López-Cánovas	2023-01-01	Experimental & molecular medicine
26593421	RNA mis-splicing in disease.	M Marina Scotti	2016-01-01	Nature reviews. Genetics
32365829	Exomes of Ductal Luminal Breast Cancer Patients from Southwest Colombia: Gene Mutational Profile and Related Expression Alterations.	Carolina Cortes-Urrea	2020-04-30	Biomolecules

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
PRPF8-203	ENST00000571958	380	116aa	ENSP00000459095
PRPF8-201	ENST00000304992	7280	2335aa	ENSP00000304350
PRPF8-205	ENST00000572621	7445	2335aa	ENSP00000460348
PRPF8-209	ENST00000573725	7073	2275aa	ENSP00000460849
PRPF8-217	ENST00000703537	2904	918aa	ENSP00000515360
PRPF8-218	ENST00000703538	7212	35aa	ENSP00000515361
PRPF8-219	ENST00000703539	3463	No protein	-
PRPF8-220	ENST00000703540	7086	2286aa	ENSP00000515362
PRPF8-221	ENST00000703541	6942	2290aa	ENSP00000515363
PRPF8-206	ENST00000572723	959	No protein	-
PRPF8-212	ENST00000575116	460	No protein	-
PRPF8-214	ENST00000576585	2157	No protein	-
PRPF8-207	ENST00000573681	1044	No protein	-
PRPF8-204	ENST00000572445	648	No protein	-
PRPF8-210	ENST00000574217	310	No protein	-
PRPF8-216	ENST00000577001	3274	1012aa	ENSP00000458151
PRPF8-215	ENST00000576958	416	No protein	-
PRPF8-213	ENST00000576407	566	No protein	-
PRPF8-208	ENST00000573716	542	No protein	-
PRPF8-222	ENST00000703542	1398	No protein	-
PRPF8-211	ENST00000574728	466	No protein	-
PRPF8-202	ENST00000571346	865	No protein	-

Gene Model

Click here to download ENSG00000174231's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000174231's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000174231	homo_sapiens	ENSP00000488611	100	100	homo_sapiens	ENSP00000304350	100	100

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000174231	homo_sapiens	ENSP00000304350	94.6039	94.0471	nomascus_leucogenys	ENSNLEP00000001053	96.9285	96.3581
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	pan_paniscus	ENSPPAP00000040194	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	pongo_abelii	ENSPPYP00000008763	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	pan_troglodytes	ENSPTRP00000060306	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	gorilla_gorilla	ENSGGOP00000005411	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	99.8715	99.7002	ornithorhynchus_anatinus	ENSOANP00000006752	99.8715	99.7002
ENSG00000174231	homo_sapiens	ENSP00000304350	99.9572	99.8287	sarcophilus_harrisii	ENSSHAP00000007096	99.9572	99.8287
ENSG00000174231	homo_sapiens	ENSP00000304350	96.788	96.6167	notamacropus_eugenii	ENSMEUP00000014641	98.3892	98.2151
ENSG00000174231	homo_sapiens	ENSP00000304350	77.773	77.773	choloepus_hoffmanni	ENSCHOP00000007615	86.3118	86.3118
ENSG00000174231	homo_sapiens	ENSP00000304350	92.9764	92.9764	dasypus_novemcinctus	ENSDNOP00000014344	99.223	99.223
ENSG00000174231	homo_sapiens	ENSP00000304350	66.0385	66.0385	erinaceus_europaeus	ENSEEUP00000011134	66.0952	66.0952
ENSG00000174231	homo_sapiens	ENSP00000304350	94.6467	94.5182	echinops_telfairi	ENSETEP00000014290	94.7278	94.5992
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	callithrix_jacchus	ENSCJAP00000003619	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	cercocebus_atys	ENSCATP00000030901	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	97.9015	97.8158	macaca_fascicularis	ENSMFAP00000042832	99.7818	99.6945
ENSG00000174231	homo_sapiens	ENSP00000304350	99.6146	99.5717	macaca_mulatta	ENSMMUP00000069673	99.4442	99.4015
ENSG00000174231	homo_sapiens	ENSP00000304350	99.6146	99.5717	macaca_nemestrina	ENSMNEP00000024684	99.4442	99.4015
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	papio_anubis	ENSPANP00000019479	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	mandrillus_leucophaeus	ENSMLEP00000027497	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	99.4861	99.4004	tursiops_truncatus	ENSTTRP00000006495	99.4861	99.4004
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	vulpes_vulpes	ENSVVUP00000029660	98.9407	98.9407
ENSG00000174231	homo_sapiens	ENSP00000304350	99.9572	99.9143	mus_spretus	MGP_SPRETEiJ_P0029649	99.9572	99.9143
ENSG00000174231	homo_sapiens	ENSP00000304350	99.5289	99.3576	equus_asinus	ENSEASP00005013671	93.9749	93.8132
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	capra_hircus	ENSCHIP00000017874	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	loxodonta_africana	ENSLAFP00000012947	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	panthera_leo	ENSPLOP00000017874	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	ailuropoda_melanoleuca	ENSAMEP00000008409	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	bos_indicus_hybrid	ENSBIXP00005007965	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	oryctolagus_cuniculus	ENSOCUP00000000075	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	equus_caballus	ENSECAP00000018808	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	10.621	9.33619	equus_caballus	ENSECAP00000078080	71.6763	63.0058
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	canis_lupus_familiaris	ENSCAFP00845020526	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	panthera_pardus	ENSPPRP00000016477	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	marmota_marmota_marmota	ENSMMMP00000027612	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	balaenoptera_musculus	ENSBMSP00010026319	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	cavia_porcellus	ENSCPOP00000009323	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	felis_catus	ENSFCAP00000033246	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	55.546	54.9036	ursus_americanus	ENSUAMP00000019788	96.9357	95.8147
ENSG00000174231	homo_sapiens	ENSP00000304350	41.9272	41.9272	ursus_americanus	ENSUAMP00000037248	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1863	99.0578	monodelphis_domestica	ENSMODP00000013136	99.9568	99.8274
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	bison_bison_bison	ENSBBBP00000014439	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	monodon_monoceros	ENSMMNP00015028209	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	sus_scrofa	ENSSSCP00000018877	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	99.9572	99.9572	microcebus_murinus	ENSMICP00000009418	99.9572	99.9572
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	octodon_degus	ENSODEP00000011385	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	97.9872	97.8158	jaculus_jaculus	ENSJJAP00000020556	99.3487	99.175
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	ovis_aries_rambouillet	ENSOARP00020029535	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	99.743	99.743	ursus_maritimus	ENSUMAP00000012872	99.9571	99.9571
ENSG00000174231	homo_sapiens	ENSP00000304350	98.6724	98.4582	ochotona_princeps	ENSOPRP00000002913	99.1394	98.9243
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	delphinapterus_leucas	ENSDLEP00000015479	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	13.7901	13.7901	physeter_catodon	ENSPCTP00005009729	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	55.2463	54.6895	physeter_catodon	ENSPCTP00005017722	97.0655	96.0873
ENSG00000174231	homo_sapiens	ENSP00000304350	99.9572	99.9143	mus_caroli	MGP_CAROLIEiJ_P0028257	99.9572	99.9143
ENSG00000174231	homo_sapiens	ENSP00000304350	99.9572	99.9143	mus_musculus	ENSMUSP00000018449	99.9572	99.9143
ENSG00000174231	homo_sapiens	ENSP00000304350	80.985	80.0428	dipodomys_ordii	ENSDORP00000005792	96.1852	95.0661
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	mustela_putorius_furo	ENSMPUP00000013129	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	aotus_nancymaae	ENSANAP00000030076	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	saimiri_boliviensis_boliviensis	ENSSBOP00000026587	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	66.5525	66.424	vicugna_pacos	ENSVPAP00000005625	66.8387	66.7097
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	chlorocebus_sabaeus	ENSCSAP00000010070	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	87.0236	86.8951	tupaia_belangeri	ENSTBEP00000005608	87.0236	86.8951
ENSG00000174231	homo_sapiens	ENSP00000304350	13.7473	13.7473	mesocricetus_auratus	ENSMAUP00000014659	99.6894	99.6894
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	phocoena_sinus	ENSPSNP00000029711	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	camelus_dromedarius	ENSCDRP00005015476	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	carlito_syrichta	ENSTSYP00000012964	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	99.9143	99.9143	panthera_tigris_altaica	ENSPTIP00000022410	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	99.9572	99.9143	rattus_norvegicus	ENSRNOP00000005016	99.9572	99.9143
ENSG00000174231	homo_sapiens	ENSP00000304350	99.9572	99.9572	prolemur_simus	ENSPSMP00000029945	99.9572	99.9572
ENSG00000174231	homo_sapiens	ENSP00000304350	99.9572	99.9572	microtus_ochrogaster	ENSMOCP00000018592	99.9572	99.9572
ENSG00000174231	homo_sapiens	ENSP00000304350	84.6253	84.4968	sorex_araneus	ENSSARP00000002691	84.7341	84.6055
ENSG00000174231	homo_sapiens	ENSP00000304350	99.9572	99.9572	peromyscus_maniculatus_bairdii	ENSPEMP00000025204	99.9572	99.9572
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	bos_mutus	ENSBMUP00000013447	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	99.9572	99.9143	mus_spicilegus	ENSMSIP00000028599	99.9572	99.9143
ENSG00000174231	homo_sapiens	ENSP00000304350	44.0685	43.8116	cricetulus_griseus_chok1gshd	ENSCGRP00001017705	98.7524	98.1766
ENSG00000174231	homo_sapiens	ENSP00000304350	13.7473	13.7473	cricetulus_griseus_chok1gshd	ENSCGRP00001009412	99.6894	99.6894
ENSG00000174231	homo_sapiens	ENSP00000304350	92.3769	92.3769	pteropus_vampyrus	ENSPVAP00000002016	92.6546	92.6546
ENSG00000174231	homo_sapiens	ENSP00000304350	99.9572	99.9143	myotis_lucifugus	ENSMLUP00000002433	99.8289	99.7861
ENSG00000174231	homo_sapiens	ENSP00000304350	99.9572	99.8287	vombatus_ursinus	ENSVURP00010010468	99.9572	99.8287
ENSG00000174231	homo_sapiens	ENSP00000304350	99.2291	99.1863	rhinolophus_ferrumequinum	ENSRFEP00010012434	99.8707	99.8276
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	neovison_vison	ENSNVIP00000013195	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	bos_taurus	ENSBTAP00000043577	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	99.9572	99.9572	heterocephalus_glaber_female	ENSHGLP00000016821	99.9572	99.9572
ENSG00000174231	homo_sapiens	ENSP00000304350	99.6146	99.5717	rhinopithecus_bieti	ENSRBIP00000014861	99.4442	99.4015
ENSG00000174231	homo_sapiens	ENSP00000304350	95.9743	95.9743	canis_lupus_dingo	ENSCAFP00020012353	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	99.2719	99.2291	sciurus_vulgaris	ENSSVLP00005014330	99.9138	99.8707
ENSG00000174231	homo_sapiens	ENSP00000304350	99.9143	99.7859	phascolarctos_cinereus	ENSPCIP00000030389	99.9572	99.8286
ENSG00000174231	homo_sapiens	ENSP00000304350	87.666	87.5803	procavia_capensis	ENSPCAP00000008490	88.0809	87.9948
ENSG00000174231	homo_sapiens	ENSP00000304350	98.3298	98.1585	nannospalax_galili	ENSNGAP00000004283	99.5663	99.3929
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	bos_grunniens	ENSBGRP00000018534	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	chinchilla_lanigera	ENSCLAP00000006197	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	cervus_hanglu_yarkandensis	ENSCHYP00000017767	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	99.3148	99.2719	catagonus_wagneri	ENSCWAP00000002024	99.9138	99.8707
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	ictidomys_tridecemlineatus	ENSSTOP00000004647	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	5.52463	5.52463	otolemur_garnettii	ENSOGAP00000011462	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	13.0193	12.7195	cebus_imitator	ENSCCAP00000039342	95	92.8125
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	cebus_imitator	ENSCCAP00000028168	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	urocitellus_parryii	ENSUPAP00010022798	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	100	100	moschus_moschiferus	ENSMMSP00000007715	100	100
ENSG00000174231	homo_sapiens	ENSP00000304350	99.6146	99.5717	rhinopithecus_roxellana	ENSRROP00000028539	99.4442	99.4015
ENSG00000174231	homo_sapiens	ENSP00000304350	99.9572	99.8287	mus_pahari	MGP_PahariEiJ_P0034998	99.9572	99.8287
ENSG00000174231	homo_sapiens	ENSP00000304350	99.9572	99.9572	propithecus_coquereli	ENSPCOP00000007853	99.9572	99.9572
ENSG00000174231	homo_sapiens	ENSP00000304350	94.3041	86.5953	caenorhabditis_elegans	C50C3.6.1	94.547	86.8184
ENSG00000174231	homo_sapiens	ENSP00000304350	96.4454	91.6488	drosophila_melanogaster	FBpp0087124	93.99	89.3155
ENSG00000174231	homo_sapiens	ENSP00000304350	19.1006	17.5161	ciona_intestinalis	ENSCINP00000035652	91.7695	84.1564
ENSG00000174231	homo_sapiens	ENSP00000304350	93.3619	90.2784	petromyzon_marinus	ENSPMAP00000006044	97.278	94.0651
ENSG00000174231	homo_sapiens	ENSP00000304350	96.1028	93.5332	eptatretus_burgeri	ENSEBUP00000010303	97.8631	95.2464
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1006	97.6017	callorhinchus_milii	ENSCMIP00000043521	99.1431	97.6435
ENSG00000174231	homo_sapiens	ENSP00000304350	92.5482	91.0492	latimeria_chalumnae	ENSLACP00000011906	97.6502	96.0687
ENSG00000174231	homo_sapiens	ENSP00000304350	99.015	97.9015	lepisosteus_oculatus	ENSLOCP00000006539	98.8879	97.7759
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1863	97.7302	clupea_harengus	ENSCHAP00000030590	99.059	97.6048
ENSG00000174231	homo_sapiens	ENSP00000304350	99.3148	97.9443	danio_rerio	ENSDARP00000121091	99.0179	97.6516
ENSG00000174231	homo_sapiens	ENSP00000304350	18.03	17.2163	carassius_auratus	ENSCARP00000130278	91.9214	87.7729
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1863	97.6017	carassius_auratus	ENSCARP00000126721	98.8898	97.31
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1435	97.6874	carassius_auratus	ENSCARP00000049911	98.8471	97.3954
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1435	97.7302	astyanax_mexicanus	ENSAMXP00000020894	99.2285	97.814
ENSG00000174231	homo_sapiens	ENSP00000304350	99.3148	97.773	ictalurus_punctatus	ENSIPUP00000034607	99.1873	97.6476
ENSG00000174231	homo_sapiens	ENSP00000304350	99.0578	97.6874	esox_lucius	ENSELUP00000030003	98.9307	97.562
ENSG00000174231	homo_sapiens	ENSP00000304350	98.9722	97.6874	electrophorus_electricus	ENSEEEP00000019161	98.9722	97.6874
ENSG00000174231	homo_sapiens	ENSP00000304350	98.9293	97.6017	oncorhynchus_kisutch	ENSOKIP00005029188	98.8024	97.4765
ENSG00000174231	homo_sapiens	ENSP00000304350	98.9722	97.6017	oncorhynchus_kisutch	ENSOKIP00005038200	98.8452	97.4765
ENSG00000174231	homo_sapiens	ENSP00000304350	98.9722	97.6445	oncorhynchus_mykiss	ENSOMYP00000047160	98.8452	97.5192
ENSG00000174231	homo_sapiens	ENSP00000304350	98.9293	97.5589	oncorhynchus_mykiss	ENSOMYP00000095285	98.8024	97.4337
ENSG00000174231	homo_sapiens	ENSP00000304350	98.4154	97.0021	salmo_salar	ENSSSAP00000055771	98.7962	97.3775
ENSG00000174231	homo_sapiens	ENSP00000304350	98.9722	97.6017	salmo_salar	ENSSSAP00000142862	98.8452	97.4765
ENSG00000174231	homo_sapiens	ENSP00000304350	98.6295	97.2163	salmo_trutta	ENSSTUP00000051930	98.3768	96.9671
ENSG00000174231	homo_sapiens	ENSP00000304350	98.5439	97.1306	salmo_trutta	ENSSTUP00000105749	98.5017	97.089
ENSG00000174231	homo_sapiens	ENSP00000304350	98.9722	97.4732	gadus_morhua	ENSGMOP00000002222	98.8452	97.3482
ENSG00000174231	homo_sapiens	ENSP00000304350	99.0578	97.7302	fundulus_heteroclitus	ENSFHEP00000019061	98.7617	97.4381
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1863	97.8158	poecilia_reticulata	ENSPREP00000032359	98.2188	96.8617
ENSG00000174231	homo_sapiens	ENSP00000304350	99.0578	97.7302	xiphophorus_maculatus	ENSXMAP00000008559	98.8039	97.4797
ENSG00000174231	homo_sapiens	ENSP00000304350	97.9872	96.7024	oryzias_latipes	ENSORLP00000029385	96.7033	95.4353
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1863	98.1585	oreochromis_niloticus	ENSONIP00000010265	98.5532	97.5319
ENSG00000174231	homo_sapiens	ENSP00000304350	98.758	97.7302	haplochromis_burtoni	ENSHBUP00000014199	98.8427	97.814
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1435	98.0728	astatotilapia_calliptera	ENSACLP00000031052	98.5106	97.4468
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1435	97.7302	sparus_aurata	ENSSAUP00010051754	99.0163	97.6048
ENSG00000174231	homo_sapiens	ENSP00000304350	99.015	97.7302	lates_calcarifer	ENSLCAP00010026303	99.0574	97.7721
ENSG00000174231	homo_sapiens	ENSP00000304350	99.5289	98.758	xenopus_tropicalis	ENSXETP00000048189	99.5289	98.758
ENSG00000174231	homo_sapiens	ENSP00000304350	99.6574	99.5289	chrysemys_picta_bellii	ENSCPBP00000028998	99.6574	99.5289
ENSG00000174231	homo_sapiens	ENSP00000304350	99.5717	99.3148	sphenodon_punctatus	ENSSPUP00000009627	99.5717	99.3148
ENSG00000174231	homo_sapiens	ENSP00000304350	98.9293	98.7152	crocodylus_porosus	ENSCPRP00005022946	99.4832	99.2679
ENSG00000174231	homo_sapiens	ENSP00000304350	99.7002	99.3576	laticauda_laticaudata	ENSLLTP00000011651	99.7002	99.3576
ENSG00000174231	homo_sapiens	ENSP00000304350	41.9272	41.7559	notechis_scutatus	ENSNSUP00000009166	100	99.5914
ENSG00000174231	homo_sapiens	ENSP00000304350	42.955	42.6981	notechis_scutatus	ENSNSUP00000009168	98.8177	98.2266
ENSG00000174231	homo_sapiens	ENSP00000304350	90.4069	89.7645	pseudonaja_textilis	ENSPTXP00000016789	93.3658	92.7023
ENSG00000174231	homo_sapiens	ENSP00000304350	95.8458	95.6745	anas_platyrhynchos_platyrhynchos	ENSAPLP00000010131	99.8661	99.6876
ENSG00000174231	homo_sapiens	ENSP00000304350	99.6574	99.4433	gallus_gallus	ENSGALP00010043664	98.1442	97.9334
ENSG00000174231	homo_sapiens	ENSP00000304350	99.6574	99.4433	meleagris_gallopavo	ENSMGAP00000004718	93.3414	93.1408
ENSG00000174231	homo_sapiens	ENSP00000304350	99.6574	99.4861	serinus_canaria	ENSSCAP00000009307	99.6574	99.4861
ENSG00000174231	homo_sapiens	ENSP00000304350	99.6574	99.4861	parus_major	ENSPMJP00000026024	99.6574	99.4861
ENSG00000174231	homo_sapiens	ENSP00000304350	80	79.2719	anolis_carolinensis	ENSACAP00000014503	97.7499	96.8603
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1863	98.1156	neolamprologus_brichardi	ENSNBRP00000017120	98.5532	97.4894
ENSG00000174231	homo_sapiens	ENSP00000304350	99.7002	99.3576	naja_naja	ENSNNAP00000001084	99.7002	99.3576
ENSG00000174231	homo_sapiens	ENSP00000304350	99.7002	99.2719	podarcis_muralis	ENSPMRP00000032045	99.7002	99.2719
ENSG00000174231	homo_sapiens	ENSP00000304350	98.2869	98.1156	geospiza_fortis	ENSGFOP00000005982	99.8695	99.6954
ENSG00000174231	homo_sapiens	ENSP00000304350	99.6574	99.4861	taeniopygia_guttata	ENSTGUP00000005862	99.6574	99.4861
ENSG00000174231	homo_sapiens	ENSP00000304350	98.8865	97.8158	erpetoichthys_calabaricus	ENSECRP00000012673	98.8442	97.774
ENSG00000174231	homo_sapiens	ENSP00000304350	98.8009	97.6874	kryptolebias_marmoratus	ENSKMAP00000021759	98.5056	97.3954
ENSG00000174231	homo_sapiens	ENSP00000304350	19.6146	18.8865	oryzias_javanicus	ENSOJAP00000012055	92.5253	89.0909
ENSG00000174231	homo_sapiens	ENSP00000304350	98.1585	96.6595	amphilophus_citrinellus	ENSACIP00000023611	97.4904	96.0017
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1006	97.6874	dicentrarchus_labrax	ENSDLAP00005013414	98.9735	97.562
ENSG00000174231	homo_sapiens	ENSP00000304350	99.2291	97.9872	amphiprion_percula	ENSAPEP00000020313	99.1018	97.8614
ENSG00000174231	homo_sapiens	ENSP00000304350	99.0578	97.8158	oryzias_sinensis	ENSOSIP00000028247	98.2583	97.0263
ENSG00000174231	homo_sapiens	ENSP00000304350	99.6574	99.4861	pelodiscus_sinensis	ENSPSIP00000015324	99.6574	99.4861
ENSG00000174231	homo_sapiens	ENSP00000304350	99.6146	99.4861	gopherus_evgoodei	ENSGEVP00005011800	99.6146	99.4861
ENSG00000174231	homo_sapiens	ENSP00000304350	99.6146	99.4433	chelonoidis_abingdonii	ENSCABP00000028243	99.6146	99.4433
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1863	97.9443	seriola_dumerili	ENSSDUP00000004138	99.059	97.8186
ENSG00000174231	homo_sapiens	ENSP00000304350	98.2869	96.8737	cottoperca_gobio	ENSCGOP00000016018	98.4134	96.9983
ENSG00000174231	homo_sapiens	ENSP00000304350	98.7152	98.3726	struthio_camelus_australis	ENSSCUP00000012532	98.6307	98.2884
ENSG00000174231	homo_sapiens	ENSP00000304350	99.6574	99.4861	anser_brachyrhynchus	ENSABRP00000012669	99.6574	99.4861
ENSG00000174231	homo_sapiens	ENSP00000304350	99.015	97.6017	gasterosteus_aculeatus	ENSGACP00000011278	98.6348	97.227
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1435	97.8158	cynoglossus_semilaevis	ENSCSEP00000012332	98.9739	97.6486
ENSG00000174231	homo_sapiens	ENSP00000304350	99.2719	97.9872	poecilia_formosa	ENSPFOP00000007460	98.3036	97.0314
ENSG00000174231	homo_sapiens	ENSP00000304350	71.1349	69.8929	myripristis_murdjan	ENSMMDP00005006973	98.6342	96.9121
ENSG00000174231	homo_sapiens	ENSP00000304350	99.015	97.773	sander_lucioperca	ENSSLUP00000029116	98.8879	97.6476
ENSG00000174231	homo_sapiens	ENSP00000304350	99.6574	99.4861	strigops_habroptila	ENSSHBP00005007936	99.6574	99.4861
ENSG00000174231	homo_sapiens	ENSP00000304350	99.2291	97.9872	amphiprion_ocellaris	ENSAOCP00000024074	99.1018	97.8614
ENSG00000174231	homo_sapiens	ENSP00000304350	99.6574	99.5289	terrapene_carolina_triunguis	ENSTMTP00000014129	99.6574	99.5289
ENSG00000174231	homo_sapiens	ENSP00000304350	98.9722	97.6017	hucho_hucho	ENSHHUP00000026547	98.8452	97.4765
ENSG00000174231	homo_sapiens	ENSP00000304350	98.9293	97.5589	hucho_hucho	ENSHHUP00000052505	98.8024	97.4337
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1863	97.9015	betta_splendens	ENSBSLP00000018472	98.8898	97.6089
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1863	97.8158	pygocentrus_nattereri	ENSPNAP00000002818	99.059	97.6903
ENSG00000174231	homo_sapiens	ENSP00000304350	99.2291	97.9872	anabas_testudineus	ENSATEP00000066484	99.1018	97.8614
ENSG00000174231	homo_sapiens	ENSP00000304350	95.2463	91.1349	ciona_savignyi	ENSCSAVP00000013332	89.8949	86.0145
ENSG00000174231	homo_sapiens	ENSP00000304350	78.2441	62.7837	saccharomyces_cerevisiae	YHR165C	75.7149	60.7542
ENSG00000174231	homo_sapiens	ENSP00000304350	68.137	67.7088	seriola_lalandi_dorsalis	ENSSLDP00000021912	99.562	98.9362
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1006	97.6017	labrus_bergylta	ENSLBEP00000035930	98.9735	97.4765
ENSG00000174231	homo_sapiens	ENSP00000304350	98.758	97.7302	pundamilia_nyererei	ENSPNYP00000021743	98.8427	97.814
ENSG00000174231	homo_sapiens	ENSP00000304350	99.2291	97.9443	mastacembelus_armatus	ENSMAMP00000013255	99.1018	97.8186
ENSG00000174231	homo_sapiens	ENSP00000304350	98.7152	97.4304	stegastes_partitus	ENSSPAP00000020819	98.927	97.6395
ENSG00000174231	homo_sapiens	ENSP00000304350	98.9293	97.6017	oncorhynchus_tshawytscha	ENSOTSP00005007725	98.8024	97.4765
ENSG00000174231	homo_sapiens	ENSP00000304350	98.9722	97.6017	oncorhynchus_tshawytscha	ENSOTSP00005017688	98.8452	97.4765
ENSG00000174231	homo_sapiens	ENSP00000304350	98.9722	97.6017	oncorhynchus_tshawytscha	ENSOTSP00005022686	98.8452	97.4765
ENSG00000174231	homo_sapiens	ENSP00000304350	99.2291	97.9872	acanthochromis_polyacanthus	ENSAPOP00000007911	99.1018	97.8614
ENSG00000174231	homo_sapiens	ENSP00000304350	43.1692	43.1263	aquila_chrysaetos_chrysaetos	ENSACCP00020007649	99.9009	99.8018
ENSG00000174231	homo_sapiens	ENSP00000304350	44.5824	44.1542	aquila_chrysaetos_chrysaetos	ENSACCP00020007679	98.9544	98.0038
ENSG00000174231	homo_sapiens	ENSP00000304350	99.3148	98.0728	nothobranchius_furzeri	ENSNFUP00015002281	98.555	97.3226
ENSG00000174231	homo_sapiens	ENSP00000304350	13.4904	13.1906	cyprinodon_variegatus	ENSCVAP00000025302	97.8261	95.6522
ENSG00000174231	homo_sapiens	ENSP00000304350	19.0578	18.4154	cyprinodon_variegatus	ENSCVAP00000025291	95.6989	92.4731
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1863	97.7302	denticeps_clupeoides	ENSDCDP00000006479	99.059	97.6048
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1435	97.8158	larimichthys_crocea	ENSLCRP00005003482	99.0163	97.6903
ENSG00000174231	homo_sapiens	ENSP00000304350	99.015	97.6874	takifugu_rubripes	ENSTRUP00000040670	98.8879	97.562
ENSG00000174231	homo_sapiens	ENSP00000304350	99.6574	99.4861	ficedula_albicollis	ENSFALP00000006913	99.6574	99.4861
ENSG00000174231	homo_sapiens	ENSP00000304350	99.015	97.6445	hippocampus_comes	ENSHCOP00000025869	98.8457	97.4776
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1435	97.7302	cyprinus_carpio_carpio	ENSCCRP00000068954	97.6793	96.2869
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1863	97.773	cyprinus_carpio_carpio	ENSCCRP00000069103	98.8898	97.4808
ENSG00000174231	homo_sapiens	ENSP00000304350	99.5289	99.1863	coturnix_japonica	ENSCJPP00005013340	98.9779	98.6371
ENSG00000174231	homo_sapiens	ENSP00000304350	97.9443	96.4882	poecilia_latipinna	ENSPLAP00000029997	98.4503	96.9867
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1435	97.6017	sinocyclocheilus_grahami	ENSSGRP00000064131	98.8471	97.31
ENSG00000174231	homo_sapiens	ENSP00000304350	97.9015	96.1456	sinocyclocheilus_grahami	ENSSGRP00000080948	98.4496	96.6839
ENSG00000174231	homo_sapiens	ENSP00000304350	99.1435	98.0728	maylandia_zebra	ENSMZEP00005020112	98.5106	97.4468
ENSG00000174231	homo_sapiens	ENSP00000304350	94.0471	92.6338	tetraodon_nigroviridis	ENSTNIP00000006047	98.4753	96.9955
ENSG00000174231	homo_sapiens	ENSP00000304350	99.2291	97.9443	paramormyrops_kingsleyae	ENSPKIP00000030374	98.7639	97.4851
ENSG00000174231	homo_sapiens	ENSP00000304350	99.0578	97.8587	scleropages_formosus	ENSSFOP00015021696	98.7617	97.5662
ENSG00000174231	homo_sapiens	ENSP00000304350	99.5717	98.758	leptobrachium_leishanense	ENSLLEP00000013479	99.5717	98.758
ENSG00000174231	homo_sapiens	ENSP00000304350	70.2784	68.9936	scophthalmus_maximus	ENSSMAP00000029323	98.7365	96.9314
ENSG00000174231	homo_sapiens	ENSP00000304350	97.8158	96.4454	oryzias_melastigma	ENSOMEP00000031784	97.8158	96.4454

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000244	involved_in spliceosomal tri-snRNP complex assembly	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0000375	involved_in RNA splicing, via transesterification reactions	1	TAS	Homo_sapiens(9606)	Process
GO:0000398	involved_in mRNA splicing, via spliceosome	3	IC,IDA,NAS	Homo_sapiens(9606)	Process
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	2	IDA,NAS	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	TAS	Homo_sapiens(9606)	Component
GO:0005682	part_of U5 snRNP	1	IBA	Homo_sapiens(9606)	Component
GO:0006397	involved_in mRNA processing	1	TAS	Homo_sapiens(9606)	Process
GO:0008233	NOT enables peptidase activity	1	IKR	Homo_sapiens(9606)	Function
GO:0008380	involved_in RNA splicing	1	TAS	Homo_sapiens(9606)	Process
GO:0016020	located_in membrane	1	HDA	Homo_sapiens(9606)	Component
GO:0016607	located_in nuclear speck	1	IEA	Homo_sapiens(9606)	Component
GO:0017070	enables U6 snRNA binding	1	IBA	Homo_sapiens(9606)	Function
GO:0030619	enables U1 snRNA binding	1	IBA	Homo_sapiens(9606)	Function
GO:0030620	enables U2 snRNA binding	1	IBA	Homo_sapiens(9606)	Function
GO:0030623	enables U5 snRNA binding	1	IBA	Homo_sapiens(9606)	Function
GO:0046540	part_of U4/U6 x U5 tri-snRNP complex	2	IDA,IPI	Homo_sapiens(9606)	Component
GO:0070530	enables K63-linked polyubiquitin modification-dependent protein binding	1	IDA	Homo_sapiens(9606)	Function
GO:0071005	part_of U2-type precatalytic spliceosome	1	IDA	Homo_sapiens(9606)	Component
GO:0071006	part_of U2-type catalytic step 1 spliceosome	1	IDA	Homo_sapiens(9606)	Component
GO:0071007	part_of U2-type catalytic step 2 spliceosome	1	IDA	Homo_sapiens(9606)	Component
GO:0071013	part_of catalytic step 2 spliceosome	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0071222	involved_in cellular response to lipopolysaccharide	1	IEA	Homo_sapiens(9606)	Process
GO:0071356	involved_in cellular response to tumor necrosis factor	1	IEA	Homo_sapiens(9606)	Process
GO:0097157	enables pre-mRNA intronic binding	1	IBA	Homo_sapiens(9606)	Function
GO:0140492	NOT enables metal-dependent deubiquitinase activity	1	IKR	Homo_sapiens(9606)	Function

Welcome to

RBP World!

Functions and Diseases

Description

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression