Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerSARS-COV-OC43FlavivirusesHIVRVSARS-COV-2SINVVEEVDengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000162613 Gene ID 8880 Accession 4004
Symbol FUBP1 Alias FBP;FUBP;hDHV Full Name far upstream element binding protein 1
Status Confidence Length 35056 bases Strand Minus strand
Position 1 : 77944055 - 77979110 RNA binding domain KH_2 , DUF1897 , KH_1
Summary The protein encoded by this gene is a single stranded DNA-binding protein that binds to multiple DNA elements, including the far upstream element (FUSE) located upstream of c-myc. Binding to FUSE occurs on the non-coding strand, and is important to the regulation of c-myc in undifferentiated cells. This protein contains three domains, an amphipathic helix N-terminal domain, a DNA-binding central domain, and a C-terminal transactivation domain that contains three tyrosine-rich motifs. The N-terminal domain is thought to repress the activity of the C-terminal domain. This protein is also thought to bind RNA, and contains 3'-5' helicase activity with in vitro activity on both DNA-DNA and RNA-RNA duplexes. Aberrant expression of this gene has been found in malignant tissues, and this gene is important to neural system and lung development. Binding of this protein to viral RNA is thought to play a role in several viral diseases, including hepatitis C and hand, foot and mouth disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000359804 KH_2 PF07650 4e-22 1
ENSP00000359804 KH_2 PF07650 4e-22 2
ENSP00000359804 KH_1 PF00013 1.2e-68 3
ENSP00000359804 KH_1 PF00013 1.2e-68 4
ENSP00000359804 KH_1 PF00013 1.2e-68 5
ENSP00000359804 KH_1 PF00013 1.2e-68 6
ENSP00000359804 DUF1897 PF09005 1.8e-10 7
ENSP00000359804 DUF1897 PF09005 1.8e-10 8
ENSP00000359803 KH_2 PF07650 4.4e-22 1
ENSP00000359803 KH_2 PF07650 4.4e-22 2
ENSP00000359803 KH_1 PF00013 1.3e-68 3
ENSP00000359803 KH_1 PF00013 1.3e-68 4
ENSP00000359803 KH_1 PF00013 1.3e-68 5
ENSP00000359803 KH_1 PF00013 1.3e-68 6
ENSP00000359803 DUF1897 PF09005 2e-10 7
ENSP00000359803 DUF1897 PF09005 2e-10 8
ENSP00000294623 KH_2 PF07650 4.7e-22 1
ENSP00000294623 KH_2 PF07650 4.7e-22 2
ENSP00000294623 KH_1 PF00013 1.2e-68 3
ENSP00000294623 KH_1 PF00013 1.2e-68 4
ENSP00000294623 KH_1 PF00013 1.2e-68 5
ENSP00000294623 KH_1 PF00013 1.2e-68 6
ENSP00000294623 DUF1897 PF09005 2e-10 7
ENSP00000294623 DUF1897 PF09005 2e-10 8
ENSP00000515388 KH_2 PF07650 5.2e-22 1
ENSP00000515388 KH_2 PF07650 5.2e-22 2
ENSP00000515388 KH_1 PF00013 1.4e-68 3
ENSP00000515388 KH_1 PF00013 1.4e-68 4
ENSP00000515388 KH_1 PF00013 1.4e-68 5
ENSP00000515388 KH_1 PF00013 1.4e-68 6
ENSP00000515388 DUF1897 PF09005 2.1e-10 7
ENSP00000515388 DUF1897 PF09005 2.1e-10 8
ENSP00000402630 KH_2 PF07650 6.1e-22 1
ENSP00000402630 KH_2 PF07650 6.1e-22 2
ENSP00000402630 KH_1 PF00013 1.6e-68 3
ENSP00000402630 KH_1 PF00013 1.6e-68 4
ENSP00000402630 KH_1 PF00013 1.6e-68 5
ENSP00000402630 KH_1 PF00013 1.6e-68 6
ENSP00000402630 DUF1897 PF09005 2.4e-10 7
ENSP00000402630 DUF1897 PF09005 2.4e-10 8
ENSP00000515389 DUF1897 PF09005 4.8e-10 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
36418423 A mass spectrometry-based approach for the identification of Kpnβ1 binding partners in cancer cells. O Michael Okpara 2022-11-23 Scientific reports
36932454 circMMD reduction following tumor treating fields inhibits glioblastoma progression through FUBP1/FIR/DVL1 and miR-15b-5p/FZD6 signaling. Shengchao Xu 2023-03-17 Journal of experimental & clinical cancer research : CR
27899653 Control of the negative IRES trans-acting factor KHSRP by ubiquitination. Yu-An Kung 2017-01-09 Nucleic acids research
33999210 dSPRINT: predicting DNA, RNA, ion, peptide and small molecule interaction sites within protein domains. Anat Etzion-Fuchs 2021-07-21 Nucleic acids research
29606613 Far Upstream Element-Binding Protein 1 Regulates LSD1 Alternative Splicing to Promote Terminal Differentiation of Neural Progenitors. Inah Hwang 2018-04-10 Stem cell reports
25662218 FUBP1: a new protagonist in splicing regulation of the DMD gene. Julie Miro 2015-02-27 Nucleic acids research
35274005 Pan-Cancer Transcriptome and Immune Infiltration Analyses Reveal the Oncogenic Role of Far Upstream Element-Binding Protein 1 (FUBP1). Huan Wang 2022-01-01 Frontiers in molecular biosciences
32481602 Multiple Functions of Fubp1 in Cell Cycle Progression and Cell Survival. Mingyu Kang 2020-05-28 Cells
23818605 Far upstream element-binding protein 1 and RNA secondary structure both mediate second-step splicing repression. Huang Li 2013-07-16 Proceedings of the National Academy of Sciences of the United States of America
34116677 The circACTN4 interacts with FUBP1 to promote tumorigenesis and progression of breast cancer by regulating the expression of proto-oncogene MYC. Xiaosong Wang 2021-06-11 Molecular cancer
37506698 FUBP1 is a general splicing factor facilitating 3' splice site recognition and splicing of long introns. Stefanie Ebersberger 2023-08-03 Molecular cell
28937658 Extracellular Vesicle-Associated RNA as a Carrier of Epigenetic Information. Maria Carlo CM Di 2017-09-22 Genes
26253612 Genetic Predisposition to Weight Loss and Regain With Lifestyle Intervention: Analyses From the Diabetes Prevention Program and the Look AHEAD Randomized Controlled Trials. D George Papandonatos 2015-12-01 Diabetes
31553912 Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing. S Jessica Elman 2019-09-24 Cell reports
32555178 NORAD orchestrates endometrial cancer progression by sequestering FUBP1 nuclear localization to promote cell apoptosis. Tong Han 2020-06-18 Cell death & disease
35558282 Selective enrichment of sialylated glycopeptides with a d-allose@SiO2 matrix. Na Sun 2018-11-16 RSC advances
34430595 Identifying a possible new target for diagnosis and treatment of postmenopausal osteoporosis through bioinformatics and clinical sample analysis. Ting Liu 2021-07-01 Annals of translational medicine
30343319 The master regulator FUBP1: its emerging role in normal cell function and malignant development. Lydie Debaize 2019-01-01 Cellular and molecular life sciences : CMLS
35546072 Far upstream element -binding protein 1 (FUBP1) participates in the malignant process and glycolysis of colon cancer cells by combining with c-Myc. Shanwei Wang 2022-05-01 Bioengineered
24086756 Novel CIC point mutations and an exon-spanning, homozygous deletion identified in oligodendroglial tumors by a comprehensive genomic approach including transcriptome sequencing. Sophie Eisenreich 2013-01-01 PloS one
33676361 Far Upstream Binding Protein 1 (FUBP1) participates in translational regulation of Nrf2 protein under oxidative stress. Wujing Dai 2021-05-01 Redox biology
27157613 MiR-16 mediates trastuzumab and lapatinib response in ErbB-2-positive breast and gastric cancer via its novel targets CCNJ and FUBP1. L Venturutti 2016-12-01 Oncogene
27566151 Alternative splicing of U2AF1 reveals a shared repression mechanism for duplicated exons. Jana Kralovicova 2017-01-09 Nucleic acids research
36082445 A pleiotropic variant in DNAJB4 is associated with multiple myeloma risk. Marco Dicanio 2023-01-15 International journal of cancer
29643205 In vitro iCLIP-based modeling uncovers how the splicing factor U2AF2 relies on regulation by cofactors. Reymond X F Sutandy 2018-05-01 Genome research
28535583 Molecular Testing of Brain Tumor. Sung-Hye Park 2017-05-01 Journal of pathology and translational medicine
33185955 Using protein microarray to identify and evaluate autoantibodies to tumor-associated antigens in ovarian cancer. Yan Ma 2021-02-01 Cancer science
35158909 RBM22, a Key Player of Pre-mRNA Splicing and Gene Expression Regulation, Is Altered in Cancer. Benoît Soubise 2022-01-27 Cancers
37180822 Far upstream element-binding protein 1 confers lobaplatin resistance by transcriptionally activating PTGES and facilitating the arachidonic acid metabolic pathway in osteosarcoma. Qiong Ma 2023-06-01 MedComm

Transcripts

Name Transcript ID bp Protein Translation ID
FUBP1-208 ENST00000483894 605 No protein -
FUBP1-207 ENST00000480673 262 No protein -
FUBP1-206 ENST00000474632 639 No protein -
FUBP1-211 ENST00000489495 2156 No protein -
FUBP1-210 ENST00000488814 612 No protein -
FUBP1-212 ENST00000492405 668 No protein -
FUBP1-213 ENST00000492724 583 No protein -
FUBP1-203 ENST00000370768 6714 644aa ENSP00000359804
FUBP1-214 ENST00000703586 3330 666aa ENSP00000515388
FUBP1-204 ENST00000421641 3426 687aa ENSP00000402630
FUBP1-201 ENST00000294623 2201 653aa ENSP00000294623
FUBP1-215 ENST00000703600 576 71aa ENSP00000515389
FUBP1-202 ENST00000370767 2524 655aa ENSP00000359803
FUBP1-209 ENST00000487684 535 No protein -
FUBP1-205 ENST00000470287 726 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
87383Body Mass Index6E-1025673413
94161Body Mass Index1E-1025673413
103628Body Mass Index2E-1025673413

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000162613homo_sapiensENSP0000029034133.275618.7175homo_sapiensENSP0000035980429.813716.7702
ENSG00000162613homo_sapiensENSP0000041719639.20623.3251homo_sapiensENSP0000035980424.534214.5963
ENSG00000162613homo_sapiensENSP0000026325737.601622.9675homo_sapiensENSP0000035980428.726717.5466
ENSG00000162613homo_sapiensENSP0000050579639.892225.3369homo_sapiensENSP0000035980422.981414.5963
ENSG00000162613homo_sapiensENSP0000036543939.655223.7069homo_sapiensENSP0000035980428.571417.0807
ENSG00000162613homo_sapiensENSP0000044876241.160225.1381homo_sapiensENSP0000035980423.136614.1304
ENSG00000162613homo_sapiensENSP0000037163433.722918.5309homo_sapiensENSP0000035980431.366517.236
ENSG00000162613homo_sapiensENSP0000025872933.160618.8256homo_sapiensENSP0000035980429.813716.9255
ENSG00000162613homo_sapiensENSP0000031817770.804259.4406homo_sapiensENSP0000035980462.888252.795
ENSG00000162613homo_sapiensENSP0000030555640.168525.2809homo_sapiensENSP0000035980422.20513.9752
ENSG00000162613homo_sapiensENSP0000043887538.658823.4714homo_sapiensENSP0000035980430.434818.4783
ENSG00000162613homo_sapiensENSP0000047114664.792557.162homo_sapiensENSP0000035980475.155366.3043

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000162613homo_sapiensENSP0000035980496.11895.9627nomascus_leucogenysENSNLEP0000001193294.072993.921
ENSG00000162613homo_sapiensENSP0000035980499.844799.8447pongo_abeliiENSPPYP0000003488296.837396.8373
ENSG00000162613homo_sapiensENSP0000035980467.080766.4596notamacropus_eugeniiENSMEUP0000000724670.243969.5935
ENSG00000162613homo_sapiensENSP0000035980499.223699.0683choloepus_hoffmanniENSCHOP0000000723397.557397.4046
ENSG00000162613homo_sapiensENSP0000035980459.006252.9503dasypus_novemcinctusENSDNOP0000002024074.074166.4717
ENSG00000162613homo_sapiensENSP0000035980485.714385.559erinaceus_europaeusENSEEUP0000000115684.274884.1221
ENSG00000162613homo_sapiensENSP0000035980459.47259.1615echinops_telfairiENSETEP0000000077059.013958.7057
ENSG00000162613homo_sapiensENSP0000035980436.64632.9193echinops_telfairiENSETEP0000001341246.365441.6503
ENSG00000162613homo_sapiensENSP0000035980499.534299.3789callithrix_jacchusENSCJAP0000007415396.246296.0961
ENSG00000162613homo_sapiensENSP0000035980499.844799.8447cercocebus_atysENSCATP0000003894398.167998.1679
ENSG00000162613homo_sapiensENSP0000035980499.534299.5342macaca_fascicularisENSMFAP0000001813196.10296.102
ENSG00000162613homo_sapiensENSP0000035980499.844799.8447macaca_mulattaENSMMUP0000006050089.930189.9301
ENSG00000162613homo_sapiensENSP0000035980499.689499.6894macaca_nemestrinaENSMNEP0000004547094.134994.1349
ENSG00000162613homo_sapiensENSP0000035980499.534299.5342papio_anubisENSPANP0000004884396.10296.102
ENSG00000162613homo_sapiensENSP0000035980499.689499.5342tursiops_truncatusENSTTRP0000000008898.015397.8626
ENSG00000162613homo_sapiensENSP0000035980498.136697.9814mus_spretusMGP_SPRETEiJ_P006348296.636196.4832
ENSG00000162613homo_sapiensENSP0000035980499.378999.2236loxodonta_africanaENSLAFP0000000272094.955594.8071
ENSG00000162613homo_sapiensENSP0000035980499.689499.3789bos_indicus_hybridENSBIXP0000502426695.111194.8148
ENSG00000162613homo_sapiensENSP0000035980499.844799.6894panthera_pardusENSPPRP0000000420498.167998.0153
ENSG00000162613homo_sapiensENSP0000035980499.844799.6894marmota_marmota_marmotaENSMMMP0000000187897.720497.5684
ENSG00000162613homo_sapiensENSP0000035980499.689499.5342balaenoptera_musculusENSBMSP0001001252796.686796.5361
ENSG00000162613homo_sapiensENSP0000035980499.223698.913cavia_porcellusENSCPOP0000000250397.112596.8085
ENSG00000162613homo_sapiensENSP0000035980485.869684.0062monodelphis_domesticaENSMODP0000004584675.753474.1096
ENSG00000162613homo_sapiensENSP0000035980499.689499.5342bison_bison_bisonENSBBBP0000000314398.015397.8626
ENSG00000162613homo_sapiensENSP0000035980499.689499.5342sus_scrofaENSSSCP0000000407596.686796.5361
ENSG00000162613homo_sapiensENSP0000035980499.378999.0683octodon_degusENSODEP0000000338997.709997.4046
ENSG00000162613homo_sapiensENSP0000035980469.409966.3043octodon_degusENSODEP0000000481785.468581.6444
ENSG00000162613homo_sapiensENSP0000035980499.223698.6025jaculus_jaculusENSJJAP0000001900098.916498.2972
ENSG00000162613homo_sapiensENSP0000035980499.689499.5342ovis_aries_rambouilletENSOARP0002002449196.686796.5361
ENSG00000162613homo_sapiensENSP0000035980482.453482.2981ochotona_princepsENSOPRP0000000110081.566881.4132
ENSG00000162613homo_sapiensENSP0000035980499.534299.3789physeter_catodonENSPCTP0000502289297.862697.7099
ENSG00000162613homo_sapiensENSP0000035980498.291998.1366mus_caroliMGP_CAROLIEiJ_P006103996.78996.6361
ENSG00000162613homo_sapiensENSP0000035980498.136697.8261mus_musculusENSMUSP0000014335496.636196.3303
ENSG00000162613homo_sapiensENSP0000035980499.534299.2236dipodomys_ordiiENSDORP0000002615897.862697.5573
ENSG00000162613homo_sapiensENSP0000035980499.844799.6894saimiri_boliviensis_boliviensisENSSBOP0000002211898.167998.0153
ENSG00000162613homo_sapiensENSP0000035980499.689499.5342vicugna_pacosENSVPAP0000000436798.769298.6154
ENSG00000162613homo_sapiensENSP00000359804100100chlorocebus_sabaeusENSCSAP00000016616100100
ENSG00000162613homo_sapiensENSP0000035980462.267162.1118tupaia_belangeriENSTBEP0000001508265.203365.0406
ENSG00000162613homo_sapiensENSP0000035980499.378999.0683mesocricetus_auratusENSMAUP0000001772697.264496.9605
ENSG00000162613homo_sapiensENSP0000035980499.844799.6894phocoena_sinusENSPSNP0000000329096.691796.5414
ENSG00000162613homo_sapiensENSP0000035980492.080791.3043carlito_syrichtaENSTSYP0000002736190.811690.0459
ENSG00000162613homo_sapiensENSP0000035980499.844799.6894panthera_tigris_altaicaENSPTIP0000002277498.167998.0153
ENSG00000162613homo_sapiensENSP0000035980498.447298.2919rattus_norvegicusENSRNOP0000007753193.925993.7778
ENSG00000162613homo_sapiensENSP0000035980499.689499.5342prolemur_simusENSPSMP0000002150298.015397.8626
ENSG00000162613homo_sapiensENSP0000035980499.068398.913microtus_ochrogasterENSMOCP0000001561297.553597.4006
ENSG00000162613homo_sapiensENSP0000035980483.540483.3851sorex_araneusENSSARP0000001061682.137481.9847
ENSG00000162613homo_sapiensENSP0000035980498.447298.1366peromyscus_maniculatus_bairdiiENSPEMP0000002534197.090496.7841
ENSG00000162613homo_sapiensENSP0000035980497.981497.8261mus_spicilegusENSMSIP0000002892894.744794.5946
ENSG00000162613homo_sapiensENSP0000035980498.447298.1366cricetulus_griseus_chok1gshdENSCGRP0000100547395.481995.1807
ENSG00000162613homo_sapiensENSP0000035980495.341695.1863pteropus_vampyrusENSPVAP0000001380193.883893.7309
ENSG00000162613homo_sapiensENSP0000035980499.223699.0683myotis_lucifugusENSMLUP0000001347695.515795.3662
ENSG00000162613homo_sapiensENSP0000035980498.136697.205vombatus_ursinusENSVURP0001001442592.128391.2536
ENSG00000162613homo_sapiensENSP0000035980499.844799.5342rhinolophus_ferrumequinumENSRFEP0001000973796.691796.391
ENSG00000162613homo_sapiensENSP0000035980483.695780.1242heterocephalus_glaber_femaleENSHGLP0000000381484.482880.8777
ENSG00000162613homo_sapiensENSP0000035980499.534299.2236heterocephalus_glaber_femaleENSHGLP0000001174095.958195.6587
ENSG00000162613homo_sapiensENSP0000035980498.291998.2919rhinopithecus_bietiENSRBIP0000003906995.04595.045
ENSG00000162613homo_sapiensENSP0000035980499.844799.6894sciurus_vulgarisENSSVLP0000502763198.167998.0153
ENSG00000162613homo_sapiensENSP0000035980499.223698.913procavia_capensisENSPCAP0000001182297.706497.4006
ENSG00000162613homo_sapiensENSP0000035980495.186395.0311nannospalax_galiliENSNGAP0000001245997.611597.4522
ENSG00000162613homo_sapiensENSP0000035980499.534299.2236chinchilla_lanigeraENSCLAP0000000801997.862697.5573
ENSG00000162613homo_sapiensENSP0000035980499.378999.2236cervus_hanglu_yarkandensisENSCHYP0000003912695.95295.8021
ENSG00000162613homo_sapiensENSP0000035980499.378999.2236catagonus_wagneriENSCWAP0000000612997.709997.5573
ENSG00000162613homo_sapiensENSP0000035980499.844799.6894ictidomys_tridecemlineatusENSSTOP0000002968197.720497.5684
ENSG00000162613homo_sapiensENSP0000035980410099.8447otolemur_garnettiiENSOGAP0000001276295.976295.8271
ENSG00000162613homo_sapiensENSP0000035980481.832381.8323cebus_imitatorENSCCAP0000003735697.773797.7737
ENSG00000162613homo_sapiensENSP0000035980496.11895.9627urocitellus_parryiiENSUPAP0001001969097.788397.6303
ENSG00000162613homo_sapiensENSP0000035980498.291998.2919rhinopithecus_roxellanaENSRROP0000004084295.04595.045
ENSG00000162613homo_sapiensENSP0000035980498.757898.6025mus_pahariMGP_PahariEiJ_P007197197.099296.9466
ENSG00000162613homo_sapiensENSP0000035980499.844799.6894propithecus_coquereliENSPCOP0000002555598.167998.0153
ENSG00000162613homo_sapiensENSP0000035980417.701911.1801caenorhabditis_elegansY119D3B.17.226.388916.6667
ENSG00000162613homo_sapiensENSP0000035980420.496912.1118caenorhabditis_elegansY59A8B.10d.131.654718.705
ENSG00000162613homo_sapiensENSP0000035980441.459626.8634caenorhabditis_elegansC36E6.1b.141.653726.9891
ENSG00000162613homo_sapiensENSP0000035980440.683224.8447caenorhabditis_elegansM01A10.1.144.709927.3038
ENSG00000162613homo_sapiensENSP0000035980423.602513.6646caenorhabditis_elegansM88.5c.117.798610.3045
ENSG00000162613homo_sapiensENSP0000035980425.155316.1491drosophila_melanogasterFBpp029352128.272318.1501
ENSG00000162613homo_sapiensENSP0000035980425.621115.2174drosophila_melanogasterFBpp030641921.153812.5641
ENSG00000162613homo_sapiensENSP0000035980423.291914.2857drosophila_melanogasterFBpp029368023.51114.4201
ENSG00000162613homo_sapiensENSP0000035980418.012411.4907ciona_intestinalisENSCINP0000000198432.49320.7283
ENSG00000162613homo_sapiensENSP0000035980415.5289.16149ciona_intestinalisENSCINP0000002595035.211320.7746
ENSG00000162613homo_sapiensENSP0000035980427.484514.1304ciona_intestinalisENSCINP0000000872629.949215.3976
ENSG00000162613homo_sapiensENSP0000035980437.267131.2112petromyzon_marinusENSPMAP0000000912974.766462.6168
ENSG00000162613homo_sapiensENSP0000035980427.950322.9814petromyzon_marinusENSPMAP0000000180472.874559.919
ENSG00000162613homo_sapiensENSP0000035980459.316849.2236petromyzon_marinusENSPMAP0000000762863.140552.3967
ENSG00000162613homo_sapiensENSP0000035980457.453446.118eptatretus_burgeriENSEBUP0000002622559.485547.7492
ENSG00000162613homo_sapiensENSP0000035980480.745375.7764callorhinchus_miliiENSCMIP0000002050177.611972.8358
ENSG00000162613homo_sapiensENSP0000035980483.850977.1739lepisosteus_oculatusENSLOCP0000000448678.488472.2384
ENSG00000162613homo_sapiensENSP0000035980482.76477.3292clupea_harengusENSCHAP0000002163076.91271.8615
ENSG00000162613homo_sapiensENSP0000035980482.298175.6211danio_rerioENSDARP0000007588382.554575.8567
ENSG00000162613homo_sapiensENSP0000035980476.242269.4099carassius_auratusENSCARP0000011310575.076568.3486
ENSG00000162613homo_sapiensENSP0000035980481.211274.0683carassius_auratusENSCARP0000007013471.742165.4321
ENSG00000162613homo_sapiensENSP0000035980470.652265.8385astyanax_mexicanusENSAMXP0000000566385.687479.8493
ENSG00000162613homo_sapiensENSP0000035980482.298176.087ictalurus_punctatusENSIPUP0000001456381.163975.0383
ENSG00000162613homo_sapiensENSP0000035980482.608775.4658esox_luciusENSELUP0000000720180.362573.4139
ENSG00000162613homo_sapiensENSP0000035980481.832374.2236oncorhynchus_kisutchENSOKIP0000509428879.969772.5341
ENSG00000162613homo_sapiensENSP0000035980481.987674.5342oncorhynchus_kisutchENSOKIP0000506377178.923871.7489
ENSG00000162613homo_sapiensENSP0000035980481.987674.5342oncorhynchus_mykissENSOMYP0000011665076.744269.7674
ENSG00000162613homo_sapiensENSP0000035980448.291939.5963oncorhynchus_mykissENSOMYP0000014160529.367324.0793
ENSG00000162613homo_sapiensENSP0000035980481.67774.2236salmo_salarENSSSAP0000003687475.574768.6782
ENSG00000162613homo_sapiensENSP0000035980481.832374.8447salmo_salarENSSSAP0000012337978.892272.1557
ENSG00000162613homo_sapiensENSP0000035980481.67774.5342salmo_truttaENSSTUP0000005456578.742571.8563
ENSG00000162613homo_sapiensENSP0000035980479.037371.7391salmo_truttaENSSTUP0000008666976.656669.5783
ENSG00000162613homo_sapiensENSP0000035980478.571470.3416gadus_morhuaENSGMOP0000004522478.086469.9074
ENSG00000162613homo_sapiensENSP0000035980482.608776.7081fundulus_heteroclitusENSFHEP0000000423281.345675.5352
ENSG00000162613homo_sapiensENSP0000035980482.608776.5528poecilia_reticulataENSPREP0000002651681.097675.1524
ENSG00000162613homo_sapiensENSP0000035980477.639871.5839xiphophorus_maculatusENSXMAP0000000727883.333376.8333
ENSG00000162613homo_sapiensENSP0000035980479.503173.2919oryzias_latipesENSORLP0000000441383.797177.2504
ENSG00000162613homo_sapiensENSP0000035980483.074576.2422cyclopterus_lumpusENSCLMP0000505089676.319570.0428
ENSG00000162613homo_sapiensENSP0000035980482.76476.7081oreochromis_niloticusENSONIP0000002314179.433773.6215
ENSG00000162613homo_sapiensENSP0000035980482.76476.7081haplochromis_burtoniENSHBUP0000000834879.433773.6215
ENSG00000162613homo_sapiensENSP0000035980482.919376.7081astatotilapia_callipteraENSACLP0000000984879.582773.6215
ENSG00000162613homo_sapiensENSP0000035980483.540477.1739sparus_aurataENSSAUP0001002211177.298971.408
ENSG00000162613homo_sapiensENSP0000035980483.540477.4845lates_calcariferENSLCAP0001005460979.234273.4904
ENSG00000162613homo_sapiensENSP0000035980493.788893.0124sphenodon_punctatusENSSPUP0000001090087.409686.686
ENSG00000162613homo_sapiensENSP0000035980460.093258.6957laticauda_laticaudataENSLLTP0000000380687.954585.9091
ENSG00000162613homo_sapiensENSP0000035980493.788892.3913notechis_scutatusENSNSUP0000000894090.827189.4737
ENSG00000162613homo_sapiensENSP0000035980495.496994.0994pseudonaja_textilisENSPTXP0000000878390.17688.8563
ENSG00000162613homo_sapiensENSP0000035980491.304389.9068anas_platyrhynchos_platyrhynchosENSAPLP0000000564195.765594.2997
ENSG00000162613homo_sapiensENSP0000035980497.360296.5839gallus_gallusENSGALP0001003262291.532890.8029
ENSG00000162613homo_sapiensENSP0000035980485.714382.9193meleagris_gallopavoENSMGAP0000002669264.561462.4561
ENSG00000162613homo_sapiensENSP0000035980496.894495.8075serinus_canariaENSSCAP0000001992196.744295.6589
ENSG00000162613homo_sapiensENSP0000035980497.049795.9627parus_majorENSPMJP0000002667394.553793.4947
ENSG00000162613homo_sapiensENSP0000035980488.509386.8012anolis_carolinensisENSACAP0000003346383.823582.2059
ENSG00000162613homo_sapiensENSP0000035980479.813773.7578neolamprologus_brichardiENSNBRP0000001963086.097279.5645
ENSG00000162613homo_sapiensENSP0000035980495.496994.0994naja_najaENSNNAP0000000223186.987385.7143
ENSG00000162613homo_sapiensENSP0000035980495.496993.9441podarcis_muralisENSPMRP0000001504186.987385.5728
ENSG00000162613homo_sapiensENSP0000035980489.44188.9752geospiza_fortisENSGFOP0000002105694.271793.7807
ENSG00000162613homo_sapiensENSP0000035980496.894495.8075taeniopygia_guttataENSTGUP0000002848096.744295.6589
ENSG00000162613homo_sapiensENSP0000035980486.180180.7453erpetoichthys_calabaricusENSECRP0000001019083.208477.961
ENSG00000162613homo_sapiensENSP0000035980482.919376.8634kryptolebias_marmoratusENSKMAP0000002562481.15575.228
ENSG00000162613homo_sapiensENSP0000035980495.652294.0994salvator_merianaeENSSMRP0000002614689.017387.5723
ENSG00000162613homo_sapiensENSP0000035980482.76476.5528oryzias_javanicusENSOJAP0000002942577.810271.9708
ENSG00000162613homo_sapiensENSP0000035980479.192573.7578amphilophus_citrinellusENSACIP0000002587282.125676.4895
ENSG00000162613homo_sapiensENSP0000035980482.919376.3975dicentrarchus_labraxENSDLAP0000506268282.534876.0433
ENSG00000162613homo_sapiensENSP0000035980480.124274.0683amphiprion_perculaENSAPEP0000001716784.590278.1967
ENSG00000162613homo_sapiensENSP0000035980482.142976.087oryzias_sinensisENSOSIP0000004303375.463669.9001
ENSG00000162613homo_sapiensENSP0000035980491.614990.9938pelodiscus_sinensisENSPSIP0000001460196.721396.0656
ENSG00000162613homo_sapiensENSP0000035980483.229877.0186seriola_dumeriliENSSDUP0000001017276.571470.8571
ENSG00000162613homo_sapiensENSP0000035980480.900674.8447cottoperca_gobioENSCGOP0000000676882.047275.9055
ENSG00000162613homo_sapiensENSP0000035980492.391391.1491struthio_camelus_australisENSSCUP0000001149491.397990.169
ENSG00000162613homo_sapiensENSP0000035980497.20596.2733anser_brachyrhynchusENSABRP0000002145294.70593.7973
ENSG00000162613homo_sapiensENSP0000035980481.987675.7764gasterosteus_aculeatusENSGACP0000002187382.629176.3693
ENSG00000162613homo_sapiensENSP0000035980482.298175.9317cynoglossus_semilaevisENSCSEP0000003337182.812576.4062
ENSG00000162613homo_sapiensENSP0000035980482.919377.0186poecilia_formosaENSPFOP0000000031981.651475.841
ENSG00000162613homo_sapiensENSP0000035980482.76476.5528myripristis_murdjanENSMMDP0000504718677.583771.7613
ENSG00000162613homo_sapiensENSP0000035980483.540476.8634sander_luciopercaENSSLUP0000000163980.298573.8806
ENSG00000162613homo_sapiensENSP0000035980497.049796.2733strigops_habroptilaENSSHBP0000501626392.182991.4454
ENSG00000162613homo_sapiensENSP0000035980496.894495.9627terrapene_carolina_triunguisENSTMTP0000001110394.259893.3535
ENSG00000162613homo_sapiensENSP0000035980491.459690.3727terrapene_carolina_triunguisENSTMTP0000002254390.615489.5385
ENSG00000162613homo_sapiensENSP000003598048.850937.76398hucho_huchoENSHHUP0000001804164.772756.8182
ENSG00000162613homo_sapiensENSP0000035980429.347824.8447hucho_huchoENSHHUP0000001804883.628370.7965
ENSG00000162613homo_sapiensENSP0000035980411.18019.78261hucho_huchoENSHHUP0000000514781.818271.5909
ENSG00000162613homo_sapiensENSP0000035980412.111811.0248hucho_huchoENSHHUP0000000515673.584966.9811
ENSG00000162613homo_sapiensENSP0000035980483.074576.3975betta_splendensENSBSLP0000005109980.209973.7631
ENSG00000162613homo_sapiensENSP0000035980483.385177.3292pygocentrus_nattereriENSPNAP0000001060881.610975.6839
ENSG00000162613homo_sapiensENSP0000035980483.229876.8634anabas_testudineusENSATEP0000002695780.601574.4361
ENSG00000162613homo_sapiensENSP0000035980413.81998.54037ciona_savignyiENSCSAVP0000000475542.38126.1905
ENSG00000162613homo_sapiensENSP000003598049.316775.59006ciona_savignyiENSCSAVP0000000721449.180329.5082
ENSG00000162613homo_sapiensENSP0000035980427.639814.1304ciona_savignyiENSCSAVP0000001881330.689715.6897
ENSG00000162613homo_sapiensENSP0000035980483.540477.3292seriola_lalandi_dorsalisENSSLDP0000002969779.117673.2353
ENSG00000162613homo_sapiensENSP0000035980483.385176.5528labrus_bergyltaENSLBEP0000001652077.826171.4493
ENSG00000162613homo_sapiensENSP0000035980483.229877.0186pundamilia_nyerereiENSPNYP0000000593082.334976.1905
ENSG00000162613homo_sapiensENSP0000035980483.540477.6398mastacembelus_armatusENSMAMP0000001104281.146375.4148
ENSG00000162613homo_sapiensENSP0000035980483.074576.8634stegastes_partitusENSSPAP0000001341981.554975.4573
ENSG00000162613homo_sapiensENSP0000035980458.229847.205oncorhynchus_tshawytschaENSOTSP0000507983757.164646.3415
ENSG00000162613homo_sapiensENSP0000035980477.484569.7205oncorhynchus_tshawytschaENSOTSP0000505238075.606168.0303
ENSG00000162613homo_sapiensENSP0000035980479.503172.5155acanthochromis_polyacanthusENSAPOP0000002913375.40568.7776
ENSG00000162613homo_sapiensENSP0000035980497.360296.5839aquila_chrysaetos_chrysaetosENSACCP0002000594797.663696.8847
ENSG00000162613homo_sapiensENSP0000035980482.453476.087nothobranchius_furzeriENSNFUP0001502240877.631671.6374
ENSG00000162613homo_sapiensENSP0000035980482.453477.0186cyprinodon_variegatusENSCVAP0000001198080.945175.6098
ENSG00000162613homo_sapiensENSP0000035980483.385176.7081larimichthys_croceaENSLCRP0000506061773.46167.5787
ENSG00000162613homo_sapiensENSP0000035980482.919375.4658takifugu_rubripesENSTRUP0000001097579.464372.3214
ENSG00000162613homo_sapiensENSP0000035980497.049795.9627ficedula_albicollisENSFALP0000003038394.69793.6364
ENSG00000162613homo_sapiensENSP0000035980483.074575.9317hippocampus_comesENSHCOP0000000016680.089873.2036
ENSG00000162613homo_sapiensENSP0000035980497.049796.2733coturnix_japonicaENSCJPP0000500961696.749295.9752
ENSG00000162613homo_sapiensENSP0000035980481.211275.4658poecilia_latipinnaENSPLAP0000003020481.591375.819
ENSG00000162613homo_sapiensENSP0000035980457.453450sinocyclocheilus_grahamiENSSGRP0000002081373.705264.1434
ENSG00000162613homo_sapiensENSP0000035980482.76474.5342sinocyclocheilus_grahamiENSSGRP0000001674280.757672.7273
ENSG00000162613homo_sapiensENSP0000035980483.229877.0186maylandia_zebraENSMZEP0000503261182.334976.1905
ENSG00000162613homo_sapiensENSP0000035980422.670820.0311tetraodon_nigroviridisENSTNIP0000002308286.390576.3314
ENSG00000162613homo_sapiensENSP0000035980424.844722.205tetraodon_nigroviridisENSTNIP0000000659559.925153.5581
ENSG00000162613homo_sapiensENSP0000035980481.987675.9317scleropages_formosusENSSFOP0001504126179.279373.4234
ENSG00000162613homo_sapiensENSP0000035980483.385177.0186scophthalmus_maximusENSSMAP0000001959775.847570.0565
ENSG00000162613homo_sapiensENSP0000035980482.298176.087oryzias_melastigmaENSOMEP0000002009178.751972.8083

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003697enables single-stranded DNA binding1TASHomo_sapiens(9606)Function
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003729enables mRNA binding1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus2IBA,IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm1IBAHomo_sapiens(9606)Component
GO:0010468involved_in regulation of gene expression2IBA,TASHomo_sapiens(9606)Process
GO:0010628involved_in positive regulation of gene expression1IDAHomo_sapiens(9606)Process

Expression