Ensembl ID ENSG00000162613 Gene ID 8880 Accession 4004
Gene Symbol FUBP1 Alias FBP;FUBP;hDHV Full Name far upstream element binding protein 1
Position 1 : 77944055 - 77979110 Length 35056 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary The protein encoded by this gene is a single stranded DNA-binding protein that binds to multiple DNA elements, including the far upstream element (FUSE) located upstream of c-myc. Binding to FUSE occurs on the non-coding strand, and is important to the regulation of c-myc in undifferentiated cells. This protein contains three domains, an amphipathic helix N-terminal domain, a DNA-binding central domain, and a C-terminal transactivation domain that contains three tyrosine-rich motifs. The N-terminal domain is thought to repress the activity of the C-terminal domain. This protein is also thought to bind RNA, and contains 3'-5' helicase activity with in vitro activity on both DNA-DNA and RNA-RNA duplexes. Aberrant expression of this gene has been found in malignant tissues, and this gene is important to neural system and lung development. Binding of this protein to viral RNA is thought to play a role in several viral diseases, including hepatitis C and hand, foot and mouth disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

ENSG00000162613 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000162613 FUBP1 0.49 4.17e-12 STAD
ENSG00000162613 FUBP1 0.91 2.42e-13 CHOL
ENSG00000162613 FUBP1 0.58 4.31e-22 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000162613 FUBP1 tumor 19637194
ENSG00000162613 FUBP1 tumors 21817013
ENSG00000162613 FUBP1 primary brain tumors 22588899
ENSG00000162613 FUBP1 tumor 22869205
ENSG00000162613 FUBP1 tumor 23071531
ENSG00000162613 FUBP1 liver cancer 23338277
ENSG00000162613 FUBP1 tumor 23527265
ENSG00000162613 FUBP1 oligodendroglial tumors 24030748
ENSG00000162613 FUBP1 tumor 24086756
ENSG00000162613 FUBP1 tumours 24117486
ENSG00000162613 FUBP1 gastric cancer 24192769
ENSG00000162613 FUBP1 tumors 24202336
ENSG00000162613 FUBP1 GBMs 24445767
ENSG00000162613 FUBP1 tumors 24559763
ENSG00000162613 FUBP1 tumor 24963357
ENSG00000162613 FUBP1 colorectal cancer 25030436
ENSG00000162613 FUBP1 tumors 25054579
ENSG00000162613 FUBP1 oligodendroglial tumors 25257301
ENSG00000162613 FUBP1 GBMs 25461780
ENSG00000162613 FUBP1 tumors 25468223
ENSG00000162613 FUBP1 tumor 25694352
ENSG00000162613 FUBP1 tumors 25943885
ENSG00000162613 FUBP1 tumour 26068201
ENSG00000162613 FUBP1 tumor 26100984
ENSG00000162613 FUBP1 tumors 26354927
ENSG00000162613 FUBP1 cancers 26469968
ENSG00000162613 FUBP1 tumor 26490982
ENSG00000162613 FUBP1 tumors 26545048
ENSG00000162613 FUBP1 tumor 26699864
ENSG00000162613 FUBP1 tumors 26925132
ENSG00000162613 FUBP1 Cancer 27148582
ENSG00000162613 FUBP1 gastric cancer 27157613
ENSG00000162613 FUBP1 tumor 27197155
ENSG00000162613 FUBP1 tumor 27852048
ENSG00000162613 FUBP1 Tumor 28076379
ENSG00000162613 FUBP1 tumors 28270234
ENSG00000162613 FUBP1 tumor 28381186
ENSG00000162613 FUBP1 cancer 28398229
ENSG00000162613 FUBP1 tumor 28535583
ENSG00000162613 FUBP1 tumor 28588622
ENSG00000162613 FUBP1 Gastric Cancer 28667493
ENSG00000162613 FUBP1 tumor 28780352
ENSG00000162613 FUBP1 tumor 29031818
ENSG00000162613 FUBP1 epithelial ovarian cancer 29113212
ENSG00000162613 FUBP1 cancer 29133573
ENSG00000162613 FUBP1 DLBCL 29245897
ENSG00000162613 FUBP1 tumor 29606613
ENSG00000162613 FUBP1 tumor 29616301
ENSG00000162613 FUBP1 tumors 29631562
ENSG00000162613 FUBP1 tumors 29752851
ENSG00000162613 FUBP1 tumor 29890994
ENSG00000162613 FUBP1 tumors 30279357
ENSG00000162613 FUBP1 pancreatic cancer 30301530
ENSG00000162613 FUBP1 tumor 30343319
ENSG00000162613 FUBP1 tumor 30417117
ENSG00000162613 FUBP1 tumor 30635626
ENSG00000162613 FUBP1 tumors 30697074
ENSG00000162613 FUBP1 tumor 31217899
ENSG00000162613 FUBP1 tumor 31423172
ENSG00000162613 FUBP1 tumour 31511046
ENSG00000162613 FUBP1 Tumor 31553912
ENSG00000162613 FUBP1 tumors 31587040
ENSG00000162613 FUBP1 bladder cancer 31725767
ENSG00000162613 FUBP1 tumor 31870915
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
ENSG00000162613 FUBP1 anaplastic oligodendroglioma sequence_alteration 19.28% (48/249) 5 entries
ENSG00000162613 FUBP1 colorectal adenocarcinoma missense_variant 2.997% (35/1168) 2 entries
ENSG00000162613 FUBP1 cecum adenocarcinoma missense_variant 4.943% (13/263) 2 entries
ENSG00000162613 FUBP1 anaplastic oligodendroglioma stop_gained 19.28% (48/249) 7 entries
ENSG00000162613 FUBP1 cecum adenocarcinoma frameshift_variant 4.943% (13/263) 2 entries
ENSG00000162613 FUBP1 colorectal adenocarcinoma frameshift_variant 2.997% (35/1168) 3 entries
ENSG00000162613 FUBP1 colon adenocarcinoma missense_variant 3.489% (44/1261) 5 entries
ENSG00000162613 FUBP1 colon adenocarcinoma frameshift_variant 3.489% (44/1261) 3 entries
ENSG00000162613 FUBP1 anaplastic oligodendroglioma missense_variant 19.28% (48/249) 2 entries
ENSG00000162613 FUBP1 anaplastic oligodendroglioma frameshift_variant 19.28% (48/249) 8 entries
ENSG00000162613 FUBP1 colon adenocarcinoma sequence_alteration 3.489% (44/1261) 3 entries
ENSG00000162613 FUBP1 colorectal adenocarcinoma sequence_alteration 2.997% (35/1168) 1 entry
ENSG00000162613 FUBP1 cecum adenocarcinoma sequence_alteration 4.943% (13/263) 1 entry
ENSG00000162613 FUBP1 urothelial carcinoma frameshift_variant 4.651% (4/86) 1 entry
ENSG00000162613 FUBP1 breast ductal adenocarcinoma missense_variant 0.8531% (14/1641) 1 entry
ENSG00000162613 FUBP1 colon adenocarcinoma stop_gained 3.489% (44/1261) 1 entry
ENSG00000162613 FUBP1 brain glioblastoma sequence_alteration 0.7988% (11/1377) 4 entries
ENSG00000162613 FUBP1 esophageal squamous cell carcinoma missense_variant 1.308% (9/688) 4 entries
ENSG00000162613 FUBP1 rectal adenocarcinoma stop_gained 0.9158% (5/546) 1 entry
ENSG00000162613 FUBP1 bile duct adenocarcinoma missense_variant 0.5141% (2/389) 2 entries
ENSG00000162613 FUBP1 skin melanoma missense_variant 1.293% (15/1160) 3 entries
ENSG00000162613 FUBP1 prostate adenocarcinoma missense_variant 0.8841% (19/2149) 2 entries
ENSG00000162613 FUBP1 osteosarcoma sequence_alteration 1.948% (3/154) 2 entries
ENSG00000162613 FUBP1 oligoastrocytoma frameshift_variant 6.25% (5/80) 2 entries
ENSG00000162613 FUBP1 chronic lymphocytic leukemia stop_gained 1.205% (11/913) 2 entries
ENSG00000162613 FUBP1 clear cell renal carcinoma frameshift_variant 0.4003% (6/1499) 2 entries
ENSG00000162613 FUBP1 small cell lung carcinoma stop_gained 0.905% (4/442) 2 entries
ENSG00000162613 FUBP1 lung adenocarcinoma sequence_alteration 0.9456% (24/2538) 1 entry
ENSG00000162613 FUBP1 prostate adenocarcinoma sequence_alteration 0.8841% (19/2149) 1 entry
ENSG00000162613 FUBP1 melanoma missense_variant 2.055% (3/146) 2 entries
ENSG00000162613 FUBP1 skin melanoma frameshift_variant 1.293% (15/1160) 1 entry
ENSG00000162613 FUBP1 bladder transitional cell carcinoma missense_variant 1.525% (7/459) 1 entry
ENSG00000162613 FUBP1 anaplastic oligodendroglioma transcript_ablation 19.28% (48/249) 1 entry
ENSG00000162613 FUBP1 Endometrial Endometrioid Adenocarcinoma missense_variant 1.855% (12/647) 1 entry
ENSG00000162613 FUBP1 lobular breast carcinoma frameshift_variant 1.158% (3/259) 2 entries
ENSG00000162613 FUBP1 urothelial carcinoma missense_variant 4.651% (4/86) 1 entry
ENSG00000162613 FUBP1 anaplastic oligoastrocytoma sequence_alteration 3.81% (4/105) 2 entries
ENSG00000162613 FUBP1 prostate carcinoma frameshift_variant 1.643% (7/426) 1 entry
ENSG00000162613 FUBP1 bladder transitional cell carcinoma stop_gained 1.525% (7/459) 1 entry
ENSG00000162613 FUBP1 hemangioblastoma sequence_alteration 11.43% (4/35) 1 entry
ENSG00000162613 FUBP1 Endometrial Endometrioid Adenocarcinoma frameshift_variant 1.855% (12/647) 1 entry
ENSG00000162613 FUBP1 esophageal adenocarcinoma sequence_alteration 1.463% (8/547) 1 entry
ENSG00000162613 FUBP1 clear cell renal carcinoma sequence_alteration 0.4003% (6/1499) 2 entries
ENSG00000162613 FUBP1 breast carcinoma missense_variant 0.3795% (6/1581) 1 entry
ENSG00000162613 FUBP1 lung adenocarcinoma stop_gained 0.9456% (24/2538) 1 entry
ENSG00000162613 FUBP1 chronic lymphocytic leukemia sequence_alteration 1.205% (11/913) 1 entry
ENSG00000162613 FUBP1 brain glioblastoma missense_variant 0.7988% (11/1377) 3 entries
ENSG00000162613 FUBP1 prostate carcinoma sequence_alteration 1.643% (7/426) 1 entry
ENSG00000162613 FUBP1 ovarian serous adenocarcinoma missense_variant 1.074% (9/838) 1 entry
ENSG00000162613 FUBP1 chronic lymphocytic leukemia frameshift_variant 1.205% (11/913) 1 entry
ENSG00000162613 FUBP1 diffuse large B-cell lymphoma stop_gained 1.078% (4/371) 2 entries
ENSG00000162613 FUBP1 Duodenal Adenocarcinoma frameshift_variant 17.65% (3/17) 1 entry
ENSG00000162613 FUBP1 squamous cell lung carcinoma missense_variant 1.073% (10/932) 2 entries
ENSG00000162613 FUBP1 clear cell renal carcinoma missense_variant 0.4003% (6/1499) 1 entry
ENSG00000162613 FUBP1 lung adenocarcinoma missense_variant 0.9456% (24/2538) 5 entries
ENSG00000162613 FUBP1 rectal adenocarcinoma missense_variant 0.9158% (5/546) 2 entries
ENSG00000162613 FUBP1 brain glioblastoma frameshift_variant 0.7988% (11/1377) 1 entry
ENSG00000162613 FUBP1 anaplastic astrocytoma missense_variant 0.5128% (1/195) 1 entry
ENSG00000162613 FUBP1 oligoastrocytoma sequence_alteration 6.25% (5/80) 1 entry
ENSG00000162613 FUBP1 alveolar rhabdomyosarcoma frameshift_variant 3.125% (2/64) 1 entry
ENSG00000162613 FUBP1 papillary thyroid carcinoma frameshift_variant 0.5917% (3/507) 1 entry
ENSG00000162613 FUBP1 neoplasm of mature B-cells frameshift_variant 1.667% (1/60) 1 entry
ENSG00000162613 FUBP1 endometrium adenocarcinoma missense_variant 3.704% (1/27) 1 entry
ENSG00000162613 FUBP1 breast carcinoma stop_gained 0.3795% (6/1581) 1 entry
ENSG00000162613 FUBP1 prostate carcinoma missense_variant 1.643% (7/426) 1 entry
ENSG00000162613 FUBP1 bladder transitional cell carcinoma frameshift_variant 1.525% (7/459) 1 entry
ENSG00000162613 FUBP1 marginal zone B-cell lymphoma sequence_alteration 3.333% (1/30) 1 entry
ENSG00000162613 FUBP1 anaplastic oligoastrocytoma frameshift_variant 3.81% (4/105) 1 entry
ENSG00000162613 FUBP1 small cell lung carcinoma missense_variant 0.905% (4/442) 1 entry
ENSG00000162613 FUBP1 testicular seminoma missense_variant 1.282% (1/78) 1 entry
ENSG00000162613 FUBP1 hemangioblastoma frameshift_variant 11.43% (4/35) 1 entry
ENSG00000162613 FUBP1 melanoma stop_gained 2.055% (3/146) 1 entry
ENSG00000162613 FUBP1 anaplastic astrocytoma sequence_alteration 0.5128% (1/195) 1 entry
ENSG00000162613 FUBP1 carcinoid tumor missense_variant 25.0% (1/4) 1 entry
ENSG00000162613 FUBP1 basal cell carcinoma stop_gained 2.941% (2/68) 1 entry
ENSG00000162613 FUBP1 hepatocellular carcinoma frameshift_variant 0.5071% (5/986) 1 entry
ENSG00000162613 FUBP1 ovarian serous adenocarcinoma sequence_alteration 1.074% (9/838) 1 entry
ENSG00000162613 FUBP1 oral squamous cell carcinoma missense_variant 0.7634% (2/262) 1 entry
ENSG00000162613 FUBP1 anaplastic astrocytoma stop_gained 0.5128% (1/195) 1 entry
ENSG00000162613 FUBP1 Merkel cell skin cancer stop_gained 1.064% (1/94) 1 entry
ENSG00000162613 FUBP1 papillary thyroid carcinoma missense_variant 0.5917% (3/507) 1 entry
ENSG00000162613 FUBP1 diffuse large B-cell lymphoma missense_variant 1.078% (4/371) 1 entry
ENSG00000162613 FUBP1 diffuse gastric adenocarcinoma missense_variant 1.22% (1/82) 1 entry
ENSG00000162613 FUBP1 non-small cell lung carcinoma stop_gained 0.9615% (1/104) 1 entry
ENSG00000162613 FUBP1 oral squamous cell carcinoma stop_gained 0.7634% (2/262) 1 entry
ENSG00000162613 FUBP1 skin melanoma sequence_alteration 1.293% (15/1160) 1 entry
ENSG00000162613 FUBP1 Mixed Lobular and Ductal Breast Carcinoma missense_variant 1.562% (1/64) 1 entry
ENSG00000162613 FUBP1 Ampulla of Vater Carcinoma sequence_alteration 2.353% (2/85) 1 entry
ENSG00000162613 FUBP1 acute myeloid leukemia missense_variant 0.3304% (3/908) 1 entry
ENSG00000162613 FUBP1 renal carcinoma stop_gained 5.0% (1/20) 1 entry
ENSG00000162613 FUBP1 gastric intestinal type adenocarcinoma missense_variant 1.176% (1/85) 1 entry
ENSG00000162613 FUBP1 basal cell carcinoma missense_variant 2.941% (2/68) 1 entry
ENSG00000162613 FUBP1 alveolar rhabdomyosarcoma missense_variant 3.125% (2/64) 1 entry
ENSG00000162613 FUBP1 osteosarcoma missense_variant 1.948% (3/154) 1 entry
ENSG00000162613 FUBP1 prostate adenocarcinoma frameshift_variant 0.8841% (19/2149) 1 entry
ENSG00000162613 FUBP1 small cell lung carcinoma sequence_alteration 0.905% (4/442) 1 entry
ENSG00000162613 FUBP1 breast carcinoma frameshift_variant 0.3795% (6/1581) 1 entry
ENSG00000162613 FUBP1 Ampulla of Vater Carcinoma missense_variant 2.353% (2/85) 1 entry
ENSG00000162613 FUBP1 anaplastic oligoastrocytoma stop_gained 3.81% (4/105) 1 entry
ENSG00000162613 FUBP1 oligoastrocytoma stop_gained 6.25% (5/80) 1 entry
ENSG00000162613 FUBP1 schwannoma missense_variant 25.0% (1/4) 1 entry
ENSG00000162613 FUBP1 papillary thyroid carcinoma sequence_alteration 0.5917% (3/507) 1 entry
ENSG00000162613 FUBP1 lung adenocarcinoma frameshift_variant 0.9456% (24/2538) 1 entry
ENSG00000162613 FUBP1 esophageal squamous cell carcinoma stop_gained 1.308% (9/688) 1 entry
ENSG00000162613 FUBP1 diffuse large B-cell lymphoma sequence_alteration 1.078% (4/371) 1 entry
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000162613 FUBP1 MESO 0.022 low
ENSG00000162613 FUBP1 PAAD 0.0069 high
ENSG00000162613 FUBP1 UCEC 0.017 high
ENSG00000162613 FUBP1 ACC 0.0029 high
ENSG00000162613 FUBP1 LGG 0.0099 high
ENSG00000162613 FUBP1 HNSC 0.021 high
ENSG00000162613 FUBP1 READ 0.0035 low
ENSG00000162613 FUBP1 KIRP 0.0013 high
ENSG00000162613 FUBP1 LUAD 0.013 high
ENSG00000162613 FUBP1 THYM 0.024 low
ENSG00000162613 FUBP1 BRCA 0.027 high
ENSG00000162613 FUBP1 COAD 0.015 low
ENSG00000162613 FUBP1 UCS 0.012 low
ENSG00000162613 FUBP1 KIRC 0.012 low
ENSG00000162613 FUBP1 PRAD 0.0047 high
ENSG00000162613 FUBP1 LAML 0.00013 low
ENSG00000162613 FUBP1 SKCM 3e-04 low
ENSG00000162613 FUBP1 CESC 0.022 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000162613 FUBP1 LUAD Del 3.517562 0.081409 0.313319 0.267442
ENSG00000162613 FUBP1 READ Del 1.970331 0.103672 0.420497 0.351515
ENSG00000162613 FUBP1 COAD Del 5.498492 0.084259 0.425127 0.288248
ENSG00000162613 FUBP1 SKCM Del 1.902439 0.085255 0.427314 0.215259
ENSG00000162613 FUBP1 HNSC Del 1.267271 0.061184 0.343128 0.180077
ENSG00000162613 FUBP1 PCPG Del 10.589301 0.197149 0.684118 0.734568
ENSG00000162613 FUBP1 BRCA Del 0.690868 0.063155 0.385631 0.300926
ENSG00000162613 FUBP1 STAD Del 1.538129 0.072668 0.365661 0.204082
ENSG00000162613 FUBP1 PRAD Del 1.609416 0.083839 0.445785 0.123984
ENSG00000162613 FUBP1 MESO Del 3.601791 0.228974 0.561850 0.298851