Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerFlavivirusesSARS-COV-2DengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000162231 Gene ID 10482 Accession 8071
Symbol NXF1 Alias TAP;MEX67 Full Name nuclear RNA export factor 1
Status Confidence Length 14180 bases Strand Minus strand
Position 11 : 62792123 - 62806302 RNA binding domain NTF2 , Tap-RNA_bind , TAP_C
Summary This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000453885 Tap-RNA_bind PF09162 9.7e-39 1
ENSP00000435742 Tap-RNA_bind PF09162 1.8e-38 1
ENSP00000435742 NTF2 PF02136 2.8e-27 2
ENSP00000294172 Tap-RNA_bind PF09162 1.9e-38 1
ENSP00000294172 TAP_C PF03943 4.3e-24 2
ENSP00000294172 NTF2 PF02136 3.1e-27 3
ENSP00000436679 Tap-RNA_bind PF09162 1.9e-38 1
ENSP00000436679 TAP_C PF03943 4.3e-24 2
ENSP00000436679 NTF2 PF02136 3.1e-27 3
ENSP00000431381 Tap-RNA_bind PF09162 1.9e-29 1
ENSP00000477375 Tap-RNA_bind PF09162 2.4e-24 1
ENSP00000434301 TAP_C PF03943 3.7e-25 1
ENSP00000434301 NTF2 PF02136 6.7e-06 2

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
11356964 Retroviral constitutive transport element evolved from cellular TAP(NXF1)-binding sequences. S A Zolotukhin 2001-06-01 Journal of virology
28977534 Fractionation iCLIP detects persistent SR protein binding to conserved, retained introns in chromatin, nucleoplasm and cytoplasm. Mattia Brugiolo 2017-10-13 Nucleic acids research
27679854 The role of TREX in gene expression and disease. G Catherine Heath 2016-10-01 The Biochemical journal
33033226 Molecular mechanism underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10. Han Feng 2020-10-27 Proceedings of the National Academy of Sciences of the United States of America
19834549 Probing the HIV-1 genomic RNA trafficking pathway and dimerization by genetic recombination and single virion analyses. D Michael Moore 2009-10-01 PLoS pathogens
25605961 Evolutionary conservation of a molecular machinery for export and expression of mRNAs with retained introns. Baomin Wang 2015-03-01 RNA (New York, N.Y.)
19019956 Efficient nuclear export of herpes simplex virus 1 transcripts requires both RNA binding by ICP27 and ICP27 interaction with TAP/NXF1. A Lisa Johnson 2009-02-01 Journal of virology
18615016 Drosophila RNAi screen identifies host genes important for influenza virus replication. Linhui Hao 2008-08-14 Nature
22505578 Epstein-Barr virus protein EB2 stimulates cytoplasmic mRNA accumulation by counteracting the deleterious effects of SRp20 on viral mRNAs. Franceline Juillard 2012-08-01 Nucleic acids research
23951221 A masked PY-NLS in Drosophila TIS11 and its mammalian homolog tristetraprolin. Laure Twyffels 2013-01-01 PloS one
24073193 Highly pathogenic avian influenza virus nucleoprotein interacts with TREX complex adaptor protein Aly/REF. T M R Vinod Balasubramaniam 2013-01-01 PloS one
29508942 Intron retention in viruses and cellular genes: Detention, border controls and passports. David Rekosh 2018-05-01 Wiley interdisciplinary reviews. RNA
15210956 A molecular link between SR protein dephosphorylation and mRNA export. Yingqun Huang 2004-06-29 Proceedings of the National Academy of Sciences of the United States of America
20227104 SR proteins SRp20 and 9G8 contribute to efficient export of herpes simplex virus 1 mRNAs. Laurimar Escudero-Paunetto 2010-06-05 Virology
33461637 Nuclear mRNA maturation and mRNA export control: from trypanosomes to opisthokonts. Susanne Kramer 2021-09-01 Parasitology
31375530 Imaging within single NPCs reveals NXF1's role in mRNA export on the cytoplasmic side of the pore. Rakefet Ben-Yishay 2019-09-02 The Journal of cell biology
34753509 An ancient retroviral RNA element hidden in mammalian genomes and its involvement in co-opted retroviral gene regulation. Koichi Kitao 2021-11-10 Retrovirology
24550725 Competitive and cooperative interactions mediate RNA transfer from herpesvirus saimiri ORF57 to the mammalian export adaptor ALYREF. B Richard Tunnicliffe 2014-02-01 PLoS pathogens
34793452 Nucleoporin TPR promotes tRNA nuclear export and protein synthesis in lung cancer cells. Miao Chen 2021-11-01 PLoS genetics
36768958 Non-Coding RNAs Regulating Mitochondrial Functions and the Oxidative Stress Response as Putative Targets against Age-Related Macular Degeneration (AMD). T M Juha Hyttinen 2023-01-30 International journal of molecular sciences
31940815 The Ebola Virus Nucleoprotein Recruits the Nuclear RNA Export Factor NXF1 into Inclusion Bodies to Facilitate Viral Protein Expression. Lisa Wendt 2020-01-11 Cells
36593289 De novo genes with an lncRNA origin encode unique human brain developmental functionality. A Ni An 2023-02-01 Nature ecology & evolution
29552131 Integrated analysis of microarray data to identify the genes critical for the rupture of intracranial aneurysm. Liang Wei 2018-04-01 Oncology letters
30218090 The m6A-methylase complex recruits TREX and regulates mRNA export. Simon Lesbirel 2018-09-14 Scientific reports
28592444 Cellular differentiation state modulates the mRNA export activity of SR proteins. Valentina Botti 2017-07-03 The Journal of cell biology

Transcripts

Name Transcript ID bp Protein Translation ID
NXF1-211 ENST00000531709 4128 356aa ENSP00000453885
NXF1-201 ENST00000294172 2290 619aa ENSP00000294172
NXF1-213 ENST00000532297 2795 619aa ENSP00000436679
NXF1-206 ENST00000527902 619 124aa ENSP00000434301
NXF1-214 ENST00000533048 922 No protein -
NXF1-216 ENST00000533499 936 No protein -
NXF1-205 ENST00000527497 529 No protein -
NXF1-207 ENST00000530875 1922 603aa ENSP00000435742
NXF1-215 ENST00000533440 579 No protein -
NXF1-212 ENST00000531872 390 No protein -
NXF1-210 ENST00000531579 590 No protein -
NXF1-203 ENST00000526163 569 No protein -
NXF1-208 ENST00000531131 1023 219aa ENSP00000477375
NXF1-217 ENST00000533671 589 115aa ENSP00000431381
NXF1-202 ENST00000525576 572 76aa ENSP00000432530
NXF1-209 ENST00000531474 548 63aa ENSP00000437296
NXF1-204 ENST00000527064 572 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000162231homo_sapiensENSP0000047253072.044757.508homo_sapiensENSP0000029417272.859558.1583
ENSG00000162231homo_sapiensENSP0000037850466.478350.8475homo_sapiensENSP0000029417257.027543.6187
ENSG00000162231homo_sapiensENSP0000048558672.044757.508homo_sapiensENSP0000029417272.859558.1583

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000162231homo_sapiensENSP0000029417265.10565.105nomascus_leucogenysENSNLEP0000000504799.752599.7525
ENSG00000162231homo_sapiensENSP00000294172100100pan_paniscusENSPPAP00000037493100100
ENSG00000162231homo_sapiensENSP0000029417299.515499.3538pongo_abeliiENSPPYP0000000363199.515499.3538
ENSG00000162231homo_sapiensENSP00000294172100100pan_troglodytesENSPTRP00000006511100100
ENSG00000162231homo_sapiensENSP0000029417210099.8384gorilla_gorillaENSGGOP0000001769110099.8384
ENSG00000162231homo_sapiensENSP0000029417289.176180.2908ornithorhynchus_anatinusENSOANP0000004159671.13464.0464
ENSG00000162231homo_sapiensENSP0000029417291.599483.1987sarcophilus_harrisiiENSSHAP0000000737188.455580.3432
ENSG00000162231homo_sapiensENSP0000029417280.93766.0743sarcophilus_harrisiiENSSHAP0000000199876.605562.5382
ENSG00000162231homo_sapiensENSP0000029417275.121268.1745notamacropus_eugeniiENSMEUP0000001210674.879267.9549
ENSG00000162231homo_sapiensENSP0000029417250.242340.8724notamacropus_eugeniiENSMEUP0000000434487.853171.4689
ENSG00000162231homo_sapiensENSP0000029417296.445992.5687dasypus_novemcinctusENSDNOP0000001744796.601992.7184
ENSG00000162231homo_sapiensENSP0000029417296.930592.4071erinaceus_europaeusENSEEUP0000000218197.087492.5566
ENSG00000162231homo_sapiensENSP0000029417275.767470.1131echinops_telfairiENSETEP0000000917877.392771.6172
ENSG00000162231homo_sapiensENSP0000029417299.353898.3845callithrix_jacchusENSCJAP0000009382499.353898.3845
ENSG00000162231homo_sapiensENSP00000294172100100cercocebus_atysENSCATP00000042951100100
ENSG00000162231homo_sapiensENSP00000294172100100macaca_fascicularisENSMFAP00000028107100100
ENSG00000162231homo_sapiensENSP00000294172100100macaca_mulattaENSMMUP00000000265100100
ENSG00000162231homo_sapiensENSP00000294172100100macaca_nemestrinaENSMNEP00000021941100100
ENSG00000162231homo_sapiensENSP00000294172100100papio_anubisENSPANP00000011419100100
ENSG00000162231homo_sapiensENSP00000294172100100mandrillus_leucophaeusENSMLEP00000006490100100
ENSG00000162231homo_sapiensENSP0000029417287.560684.0065tursiops_truncatusENSTTRP0000000232687.702384.1424
ENSG00000162231homo_sapiensENSP0000029417296.122892.5687vulpes_vulpesENSVVUP0000004198784.51781.392
ENSG00000162231homo_sapiensENSP0000029417297.092193.6995equus_asinusENSEASP0000501641797.249293.8511
ENSG00000162231homo_sapiensENSP0000029417297.092192.5687capra_hircusENSCHIP0000000626993.034188.6997
ENSG00000162231homo_sapiensENSP0000029417296.122893.0533loxodonta_africanaENSLAFP0000000569996.434493.3549
ENSG00000162231homo_sapiensENSP0000029417297.899894.9919panthera_leoENSPLOP0000001099598.058395.1456
ENSG00000162231homo_sapiensENSP0000029417298.061494.1842ailuropoda_melanoleucaENSAMEP0000003537091.141187.5375
ENSG00000162231homo_sapiensENSP0000029417297.253693.0533bos_indicus_hybridENSBIXP0000500577897.096892.9032
ENSG00000162231homo_sapiensENSP0000029417295.476691.5994oryctolagus_cuniculusENSOCUP0000003608289.545585.9091
ENSG00000162231homo_sapiensENSP0000029417288.045285.622equus_caballusENSECAP0000000361697.495594.8122
ENSG00000162231homo_sapiensENSP0000029417296.930593.3764canis_lupus_familiarisENSCAFP0084501081795.087291.6006
ENSG00000162231homo_sapiensENSP0000029417297.899894.9919panthera_pardusENSPPRP0000001006598.058395.1456
ENSG00000162231homo_sapiensENSP0000029417297.092192.8918marmota_marmota_marmotaENSMMMP0000000378597.092192.8918
ENSG00000162231homo_sapiensENSP0000029417296.122892.4071balaenoptera_musculusENSBMSP0001001181690.978687.4618
ENSG00000162231homo_sapiensENSP0000029417298.384595.4766cavia_porcellusENSCPOP0000000552698.543795.6311
ENSG00000162231homo_sapiensENSP0000029417297.899894.9919felis_catusENSFCAP0000001370598.058395.1456
ENSG00000162231homo_sapiensENSP0000029417293.376489.0145ursus_americanusENSUAMP0000003407493.225888.871
ENSG00000162231homo_sapiensENSP0000029417291.760983.1987monodelphis_domesticaENSMODP0000001005991.025682.5321
ENSG00000162231homo_sapiensENSP0000029417278.029160.5816monodelphis_domesticaENSMODP0000002767773.181856.8182
ENSG00000162231homo_sapiensENSP0000029417295.638191.5994bison_bison_bisonENSBBBP0000001168895.483991.4516
ENSG00000162231homo_sapiensENSP0000029417296.122892.7302monodon_monocerosENSMMNP0001502730495.967792.5806
ENSG00000162231homo_sapiensENSP0000029417295.638191.7609sus_scrofaENSSSCP0000006095882.108278.7795
ENSG00000162231homo_sapiensENSP0000029417299.030797.4152microcebus_murinusENSMICP0000003875299.190997.5728
ENSG00000162231homo_sapiensENSP0000029417296.284390.6301octodon_degusENSODEP0000000207298.026392.2697
ENSG00000162231homo_sapiensENSP0000029417295.961292.7302jaculus_jaculusENSJJAP0000001528095.498492.283
ENSG00000162231homo_sapiensENSP0000029417297.092192.7302ovis_aries_rambouilletENSOARP0002002743496.935592.5806
ENSG00000162231homo_sapiensENSP0000029417297.092192.8918ursus_maritimusENSUMAP0000001987694.79590.694
ENSG00000162231homo_sapiensENSP0000029417272.213269.9515ochotona_princepsENSOPRP0000000217172.330170.0647
ENSG00000162231homo_sapiensENSP0000029417296.122892.4071delphinapterus_leucasENSDLEP0000002510187.628984.2415
ENSG00000162231homo_sapiensENSP0000029417295.31592.2456physeter_catodonENSPCTP0000502417296.721393.6066
ENSG00000162231homo_sapiensENSP0000029417295.153590.6301mus_caroliMGP_CAROLIEiJ_P004801395.307490.7767
ENSG00000162231homo_sapiensENSP0000029417295.153591.1147mus_musculusENSMUSP0000001024195.307491.2621
ENSG00000162231homo_sapiensENSP0000029417276.575173.8288dipodomys_ordiiENSDORP0000002573489.43486.2264
ENSG00000162231homo_sapiensENSP0000029417297.576793.8611mustela_putorius_furoENSMPUP0000001355597.734694.0129
ENSG00000162231homo_sapiensENSP0000029417298.061496.2843aotus_nancymaaeENSANAP0000001342097.275695.5128
ENSG00000162231homo_sapiensENSP0000029417299.192298.2229saimiri_boliviensis_boliviensisENSSBOP0000000560999.192298.2229
ENSG00000162231homo_sapiensENSP0000029417210099.8384chlorocebus_sabaeusENSCSAP0000000302410099.8384
ENSG00000162231homo_sapiensENSP0000029417277.059875.4443tupaia_belangeriENSTBEP0000001184181.678179.9658
ENSG00000162231homo_sapiensENSP0000029417296.607494.1842mesocricetus_auratusENSMAUP0000001499496.763894.3366
ENSG00000162231homo_sapiensENSP0000029417295.799791.7609phocoena_sinusENSPSNP0000002690295.645291.6129
ENSG00000162231homo_sapiensENSP0000029417297.092193.6995camelus_dromedariusENSCDRP0000500694997.249293.8511
ENSG00000162231homo_sapiensENSP0000029417298.384596.769carlito_syrichtaENSTSYP0000001926098.543796.9256
ENSG00000162231homo_sapiensENSP0000029417296.122893.2149panthera_tigris_altaicaENSPTIP0000000724896.122893.2149
ENSG00000162231homo_sapiensENSP0000029417294.507391.4378rattus_norvegicusENSRNOP0000008181294.507391.4378
ENSG00000162231homo_sapiensENSP0000029417298.707697.2536prolemur_simusENSPSMP0000003348298.867397.411
ENSG00000162231homo_sapiensENSP0000029417294.991990.4685microtus_ochrogasterENSMOCP0000000124995.454590.9091
ENSG00000162231homo_sapiensENSP0000029417268.497666.559sorex_araneusENSSARP0000001248985.483983.0645
ENSG00000162231homo_sapiensENSP0000029417294.184289.8223peromyscus_maniculatus_bairdiiENSPEMP0000000412494.489590.1134
ENSG00000162231homo_sapiensENSP0000029417297.253693.0533bos_mutusENSBMUP0000003153197.096892.9032
ENSG00000162231homo_sapiensENSP0000029417295.31591.2763mus_spicilegusENSMSIP0000003745795.469391.424
ENSG00000162231homo_sapiensENSP0000029417296.76993.8611cricetulus_griseus_chok1gshdENSCGRP0000101229796.925694.0129
ENSG00000162231homo_sapiensENSP0000029417297.092193.8611pteropus_vampyrusENSPVAP0000000330697.249294.0129
ENSG00000162231homo_sapiensENSP0000029417295.799791.7609myotis_lucifugusENSMLUP0000001016495.799791.7609
ENSG00000162231homo_sapiensENSP0000029417292.568783.5218vombatus_ursinusENSVURP0001000172391.826982.8526
ENSG00000162231homo_sapiensENSP0000029417293.53889.3376rhinolophus_ferrumequinumENSRFEP0001001775993.086888.9068
ENSG00000162231homo_sapiensENSP0000029417296.76993.0533neovison_visonENSNVIP0000002664394.479590.8517
ENSG00000162231homo_sapiensENSP0000029417292.407187.8837bos_taurusENSBTAP0000001248691.373886.901
ENSG00000162231homo_sapiensENSP0000029417295.476691.9225heterocephalus_glaber_femaleENSHGLP0000000398996.097692.5203
ENSG00000162231homo_sapiensENSP00000294172100100rhinopithecus_bietiENSRBIP00000037915100100
ENSG00000162231homo_sapiensENSP0000029417297.738394.5073canis_lupus_dingoENSCAFP0002001638397.896494.6602
ENSG00000162231homo_sapiensENSP0000029417297.415294.8304sciurus_vulgarisENSSVLP0000500612197.572894.9838
ENSG00000162231homo_sapiensENSP0000029417249.757736.5105phascolarctos_cinereusENSPCIP0000004255061.723445.2906
ENSG00000162231homo_sapiensENSP0000029417292.730284.3296phascolarctos_cinereusENSPCIP0000001997791.987283.6538
ENSG00000162231homo_sapiensENSP0000029417250.080839.58phascolarctos_cinereusENSPCIP0000005018078.282861.8687
ENSG00000162231homo_sapiensENSP0000029417294.830491.1147procavia_capensisENSPCAP0000001555495.137891.41
ENSG00000162231homo_sapiensENSP0000029417296.122894.1842nannospalax_galiliENSNGAP0000000213096.122894.1842
ENSG00000162231homo_sapiensENSP0000029417298.384595.1535chinchilla_lanigeraENSCLAP0000000205098.543795.3074
ENSG00000162231homo_sapiensENSP0000029417295.638191.7609cervus_hanglu_yarkandensisENSCHYP0000002807895.024191.1718
ENSG00000162231homo_sapiensENSP0000029417296.76992.7302catagonus_wagneriENSCWAP0000002415577.994874.7396
ENSG00000162231homo_sapiensENSP0000029417294.184290.1454ictidomys_tridecemlineatusENSSTOP0000002774093.13189.1374
ENSG00000162231homo_sapiensENSP0000029417296.122893.6995otolemur_garnettiiENSOGAP0000000798395.967793.5484
ENSG00000162231homo_sapiensENSP0000029417299.353898.3845cebus_imitatorENSCCAP0000002561799.353898.3845
ENSG00000162231homo_sapiensENSP0000029417295.961292.2456urocitellus_parryiiENSUPAP0001000667862.39559.979
ENSG00000162231homo_sapiensENSP0000029417249.757745.7189moschus_moschiferusENSMMSP0000000437387.005779.9435
ENSG00000162231homo_sapiensENSP0000029417296.284391.2763moschus_moschiferusENSMMSP0000001635393.416988.558
ENSG00000162231homo_sapiensENSP00000294172100100rhinopithecus_roxellanaENSRROP00000041969100100
ENSG00000162231homo_sapiensENSP0000029417295.638192.2456mus_pahariMGP_PahariEiJ_P002101795.948192.5446
ENSG00000162231homo_sapiensENSP0000029417298.707697.0921propithecus_coquereliENSPCOP0000002450798.867397.2492
ENSG00000162231homo_sapiensENSP0000029417232.794818.0937caenorhabditis_elegansC15H11.6.150.123527.6543
ENSG00000162231homo_sapiensENSP0000029417242.972524.8788caenorhabditis_elegansC15H11.3.143.678225.2874
ENSG00000162231homo_sapiensENSP0000029417239.5821.6478drosophila_melanogasterFBpp042432339.837421.7886
ENSG00000162231homo_sapiensENSP0000029417221.970913.2472drosophila_melanogasterFBpp008110245.182727.2425
ENSG00000162231homo_sapiensENSP0000029417251.696332.1486drosophila_melanogasterFBpp007326747.61929.6131
ENSG00000162231homo_sapiensENSP0000029417243.618724.7173drosophila_melanogasterFBpp008848332.104618.1926
ENSG00000162231homo_sapiensENSP0000029417252.827133.1179ciona_intestinalisENSCINP0000002648253.606633.6066
ENSG00000162231homo_sapiensENSP0000029417229.402324.7173petromyzon_marinusENSPMAP0000000950771.936860.4743
ENSG00000162231homo_sapiensENSP0000029417251.534739.4184eptatretus_burgeriENSEBUP0000002246276.498858.5132
ENSG00000162231homo_sapiensENSP0000029417215.185810.8239callorhinchus_miliiENSCMIP0000000489255.952439.881
ENSG00000162231homo_sapiensENSP0000029417286.591372.3748latimeria_chalumnaeENSLACP0000000137485.350371.3376
ENSG00000162231homo_sapiensENSP0000029417265.428152.3425lepisosteus_oculatusENSLOCP0000000142978.488462.7907
ENSG00000162231homo_sapiensENSP0000029417273.505761.5509clupea_harengusENSCHAP0000002251172.683760.8626
ENSG00000162231homo_sapiensENSP0000029417273.990359.1276clupea_harengusENSCHAP0000005936171.11856.8323
ENSG00000162231homo_sapiensENSP0000029417266.074348.7884danio_rerioENSDARP0000010945767.049249.5082
ENSG00000162231homo_sapiensENSP0000029417278.352263.0048danio_rerioENSDARP0000007184875.545260.7477
ENSG00000162231homo_sapiensENSP0000029417270.759353.6349carassius_auratusENSCARP0000006170667.697151.3138
ENSG00000162231homo_sapiensENSP0000029417273.02158.4814carassius_auratusENSCARP0000013249869.753155.8642
ENSG00000162231homo_sapiensENSP0000029417273.828858.9661carassius_auratusENSCARP0000013269571.294956.9423
ENSG00000162231homo_sapiensENSP0000029417272.536358.1583carassius_auratusENSCARP0000006764469.828955.9876
ENSG00000162231homo_sapiensENSP0000029417273.990360.5816astyanax_mexicanusENSAMXP0000004720771.339658.4112
ENSG00000162231homo_sapiensENSP0000029417276.090562.6817astyanax_mexicanusENSAMXP0000005132371.14858.6103
ENSG00000162231homo_sapiensENSP0000029417271.243956.3813ictalurus_punctatusENSIPUP0000002952367.021353.0395
ENSG00000162231homo_sapiensENSP0000029417275.444360.9047ictalurus_punctatusENSIPUP0000003091873.659359.4637
ENSG00000162231homo_sapiensENSP0000029417276.736762.1971esox_luciusENSELUP0000007035375.878661.5016
ENSG00000162231homo_sapiensENSP0000029417261.712448.1422esox_luciusENSELUP0000005993172.761956.7619
ENSG00000162231homo_sapiensENSP0000029417274.959661.0662electrophorus_electricusENSEEEP0000003445573.534159.9049
ENSG00000162231homo_sapiensENSP0000029417271.890158.9661electrophorus_electricusENSEEEP0000003963069.640157.1205
ENSG00000162231homo_sapiensENSP0000029417276.413661.7124oncorhynchus_kisutchENSOKIP0000508970674.723560.3475
ENSG00000162231homo_sapiensENSP0000029417264.620451.5347oncorhynchus_kisutchENSOKIP0000503054275.901360.5313
ENSG00000162231homo_sapiensENSP0000029417276.413661.2278oncorhynchus_kisutchENSOKIP0000509298474.488259.685
ENSG00000162231homo_sapiensENSP0000029417275.121260.42oncorhynchus_mykissENSOMYP0000002008174.281259.7444
ENSG00000162231homo_sapiensENSP0000029417276.413661.5509oncorhynchus_mykissENSOMYP0000007216274.605760.0946
ENSG00000162231homo_sapiensENSP0000029417277.867562.5202oncorhynchus_mykissENSOMYP0000009645276.386761.3312
ENSG00000162231homo_sapiensENSP0000029417275.605861.3893salmo_salarENSSSAP0000008992372.445858.8235
ENSG00000162231homo_sapiensENSP0000029417274.959659.6123salmo_salarENSSSAP0000005181170.94856.422
ENSG00000162231homo_sapiensENSP0000029417277.867562.6817salmo_salarENSSSAP0000005151376.265861.3924
ENSG00000162231homo_sapiensENSP0000029417276.575161.5509salmo_truttaENSSTUP0000007414873.716959.2535
ENSG00000162231homo_sapiensENSP0000029417275.928961.2278salmo_truttaENSSTUP0000005726774.015759.685
ENSG00000162231homo_sapiensENSP0000029417269.7955.7351salmo_truttaENSSTUP0000000282075.524560.3147
ENSG00000162231homo_sapiensENSP0000029417276.413660.2585gadus_morhuaENSGMOP0000002932968.950454.3732
ENSG00000162231homo_sapiensENSP0000029417276.736758.3199fundulus_heteroclitusENSFHEP0000002218772.852855.3681
ENSG00000162231homo_sapiensENSP0000029417277.70659.7738poecilia_reticulataENSPREP0000002267572.113955.4723
ENSG00000162231homo_sapiensENSP0000029417274.636558.3199xiphophorus_maculatusENSXMAP0000000317473.217157.2108
ENSG00000162231homo_sapiensENSP0000029417277.221359.2892oryzias_latipesENSORLP0000000306271.879755.188
ENSG00000162231homo_sapiensENSP0000029417275.928959.6123cyclopterus_lumpusENSCLMP0000501892374.249658.2938
ENSG00000162231homo_sapiensENSP0000029417278.513761.2278oreochromis_niloticusENSONIP0000003577973.748157.5114
ENSG00000162231homo_sapiensENSP0000029417278.029161.5509haplochromis_burtoniENSHBUP0000001126775.586959.6244
ENSG00000162231homo_sapiensENSP0000029417277.382961.3893astatotilapia_callipteraENSACLP0000002527073.241658.104
ENSG00000162231homo_sapiensENSP0000029417271.728656.5428sparus_aurataENSSAUP0001004533974.621858.8235
ENSG00000162231homo_sapiensENSP0000029417277.70661.0662lates_calcariferENSLCAP0001004346267.937953.3898
ENSG00000162231homo_sapiensENSP0000029417275.282760.0969xenopus_tropicalisENSXETP0000008723375.040359.9034
ENSG00000162231homo_sapiensENSP0000029417286.591372.8595chrysemys_picta_belliiENSCPBP0000003413584.944571.4739
ENSG00000162231homo_sapiensENSP0000029417284.16870.4362sphenodon_punctatusENSSPUP0000001037482.698469.2064
ENSG00000162231homo_sapiensENSP0000029417271.082455.7351laticauda_laticaudataENSLLTP0000000211073.578657.6923
ENSG00000162231homo_sapiensENSP0000029417275.928961.874notechis_scutatusENSNSUP0000001769077.943663.5158
ENSG00000162231homo_sapiensENSP0000029417267.851453.3118pseudonaja_textilisENSPTXP0000001357477.490860.8856
ENSG00000162231homo_sapiensENSP0000029417273.505764.2973anas_platyrhynchos_platyrhynchosENSAPLP0000002099869.465760.7634
ENSG00000162231homo_sapiensENSP0000029417285.783575.6058gallus_gallusENSGALP0001000153671.853963.3288
ENSG00000162231homo_sapiensENSP0000029417270.274658.3199anolis_carolinensisENSACAP0000001563871.194859.0835
ENSG00000162231homo_sapiensENSP0000029417278.513762.3586neolamprologus_brichardiENSNBRP0000000146175.232259.7523
ENSG00000162231homo_sapiensENSP0000029417279.967765.7512naja_najaENSNNAP0000001371465.737154.0505
ENSG00000162231homo_sapiensENSP0000029417275.444363.0048podarcis_muralisENSPMRP0000002748979.692866.5529
ENSG00000162231homo_sapiensENSP0000029417284.16871.8901taeniopygia_guttataENSTGUP0000001928045.581838.9326
ENSG00000162231homo_sapiensENSP0000029417281.098569.1438taeniopygia_guttataENSTGUP0000002974351.699344.0783
ENSG00000162231homo_sapiensENSP0000029417277.221364.7819erpetoichthys_calabaricusENSECRP0000001560274.804462.7543
ENSG00000162231homo_sapiensENSP0000029417277.70660.9047kryptolebias_marmoratusENSKMAP0000000535572.54956.8627
ENSG00000162231homo_sapiensENSP0000029417279.321563.0048salvator_merianaeENSSMRP0000001335678.5662.4
ENSG00000162231homo_sapiensENSP0000029417276.25258.8045oryzias_javanicusENSOJAP0000002796970.553154.4096
ENSG00000162231homo_sapiensENSP0000029417277.70661.5509amphilophus_citrinellusENSACIP0000002911876.228260.3803
ENSG00000162231homo_sapiensENSP0000029417266.882152.3425dicentrarchus_labraxENSDLAP0000500971568.092153.2895
ENSG00000162231homo_sapiensENSP0000029417276.575159.9354amphiprion_perculaENSAPEP0000001377174.763458.5173
ENSG00000162231homo_sapiensENSP0000029417277.221359.2892oryzias_sinensisENSOSIP0000004381071.771855.1051
ENSG00000162231homo_sapiensENSP0000029417281.744868.6591pelodiscus_sinensisENSPSIP0000000687982.950869.6721
ENSG00000162231homo_sapiensENSP0000029417285.460472.2132gopherus_evgoodeiENSGEVP0000501148570.627559.6796
ENSG00000162231homo_sapiensENSP0000029417285.298971.4055chelonoidis_abingdoniiENSCABP0000002972183.544369.9367
ENSG00000162231homo_sapiensENSP0000029417277.70661.2278seriola_dumeriliENSSDUP0000002380571.79156.5672
ENSG00000162231homo_sapiensENSP0000029417274.959658.3199cottoperca_gobioENSCGOP0000002881073.417757.1203
ENSG00000162231homo_sapiensENSP0000029417286.914477.2213anser_brachyrhynchusENSABRP0000002545386.774277.0968
ENSG00000162231homo_sapiensENSP0000029417276.575159.9354gasterosteus_aculeatusENSGACP000000223977558.7025
ENSG00000162231homo_sapiensENSP0000029417277.867561.5509cynoglossus_semilaevisENSCSEP0000000901574.039958.5253
ENSG00000162231homo_sapiensENSP0000029417277.867560.0969poecilia_formosaENSPFOP0000000931977.1259.52
ENSG00000162231homo_sapiensENSP0000029417267.528353.6349myripristis_murdjanENSMMDP0000504398572.443757.539
ENSG00000162231homo_sapiensENSP0000029417278.513761.0662sander_luciopercaENSSLUP0000003822272.645756.5022
ENSG00000162231homo_sapiensENSP0000029417285.62274.475strigops_habroptilaENSSHBP0000500907883.728372.8278
ENSG00000162231homo_sapiensENSP0000029417275.121258.4814amphiprion_ocellarisENSAOCP0000001246275.48758.7662
ENSG00000162231homo_sapiensENSP0000029417286.752873.3441terrapene_carolina_triunguisENSTMTP0000000927884.834171.722
ENSG00000162231homo_sapiensENSP0000029417276.575161.874hucho_huchoENSHHUP0000008271074.881560.5055
ENSG00000162231homo_sapiensENSP0000029417275.121260.2585hucho_huchoENSHHUP0000002102570.454556.5152
ENSG00000162231homo_sapiensENSP0000029417277.70662.3586hucho_huchoENSHHUP0000004138775.987460.9795
ENSG00000162231homo_sapiensENSP0000029417277.382960.7431betta_splendensENSBSLP0000004264973.579157.7573
ENSG00000162231homo_sapiensENSP0000029417276.413662.1971pygocentrus_nattereriENSPNAP0000000470174.371160.5346
ENSG00000162231homo_sapiensENSP0000029417275.767461.2278pygocentrus_nattereriENSPNAP0000002011473.974859.7792
ENSG00000162231homo_sapiensENSP0000029417277.867560.42anabas_testudineusENSATEP0000004753574.497757.8053
ENSG00000162231homo_sapiensENSP0000029417246.04228.5945ciona_savignyiENSCSAVP0000001329658.044836.0489
ENSG00000162231homo_sapiensENSP0000029417241.195522.294saccharomyces_cerevisiaeYPL169C42.57123.0384
ENSG00000162231homo_sapiensENSP0000029417272.213256.8659seriola_lalandi_dorsalisENSSLDP0000002055979.679162.7451
ENSG00000162231homo_sapiensENSP0000029417278.029160.7431labrus_bergyltaENSLBEP0000000777075.116658.4759
ENSG00000162231homo_sapiensENSP0000029417278.513762.1971pundamilia_nyerereiENSPNYP0000001944477.142961.1111
ENSG00000162231homo_sapiensENSP0000029417274.798159.1276mastacembelus_armatusENSMAMP0000005540373.375658.0032
ENSG00000162231homo_sapiensENSP0000029417268.659152.6656stegastes_partitusENSSPAP0000000962572.898855.9177
ENSG00000162231homo_sapiensENSP0000029417276.413661.7124oncorhynchus_tshawytschaENSOTSP0000506816074.605760.2524
ENSG00000162231homo_sapiensENSP0000029417277.867562.5202oncorhynchus_tshawytschaENSOTSP0000501906776.386761.3312
ENSG00000162231homo_sapiensENSP0000029417273.667258.4814oncorhynchus_tshawytschaENSOTSP0000507909169.300955.0152
ENSG00000162231homo_sapiensENSP0000029417276.736760.0969acanthochromis_polyacanthusENSAPOP0000001390875.039558.7678
ENSG00000162231homo_sapiensENSP0000029417286.591376.252aquila_chrysaetos_chrysaetosENSACCP0002001785987.154576.748
ENSG00000162231homo_sapiensENSP0000029417275.767459.9354nothobranchius_furzeriENSNFUP0001501251575.0459.36
ENSG00000162231homo_sapiensENSP0000029417275.282758.8045cyprinodon_variegatusENSCVAP0000000506875.161358.7097
ENSG00000162231homo_sapiensENSP0000029417273.505759.4507denticeps_clupeoidesENSDCDP0000001682173.743959.6434
ENSG00000162231homo_sapiensENSP0000029417273.505759.2892denticeps_clupeoidesENSDCDP0000001732073.983759.6748
ENSG00000162231homo_sapiensENSP0000029417275.767461.3893denticeps_clupeoidesENSDCDP0000004252875.0460.8
ENSG00000162231homo_sapiensENSP0000029417278.190660.9047larimichthys_croceaENSLCRP0000505195573.001556.8627
ENSG00000162231homo_sapiensENSP0000029417276.413659.7738takifugu_rubripesENSTRUP0000007790275.801359.2949
ENSG00000162231homo_sapiensENSP0000029417264.135749.4346hippocampus_comesENSHCOP0000002819677.690859.8826
ENSG00000162231homo_sapiensENSP0000029417233.117922.294cyprinus_carpio_carpioENSCCRP0000014284255.405437.2973
ENSG00000162231homo_sapiensENSP0000029417274.959660.9047cyprinus_carpio_carpioENSCCRP0000013132673.534159.7464
ENSG00000162231homo_sapiensENSP0000029417270.113153.1502cyprinus_carpio_carpioENSCCRP0000004115269.108352.3885
ENSG00000162231homo_sapiensENSP0000029417276.413662.3586cyprinus_carpio_carpioENSCCRP0000017230670.282357.3551
ENSG00000162231homo_sapiensENSP0000029417278.029160.0969poecilia_latipinnaENSPLAP0000003145672.197355.6054
ENSG00000162231homo_sapiensENSP0000029417249.27337.8029sinocyclocheilus_grahamiENSSGRP0000007235763.807548.954
ENSG00000162231homo_sapiensENSP0000029417277.867563.3279sinocyclocheilus_grahamiENSSGRP0000010635975.667261.5385
ENSG00000162231homo_sapiensENSP0000029417277.544463.3279sinocyclocheilus_grahamiENSSGRP0000006962274.188660.5873
ENSG00000162231homo_sapiensENSP0000029417246.203633.1179sinocyclocheilus_grahamiENSSGRP0000003967056.299240.3543
ENSG00000162231homo_sapiensENSP0000029417277.382961.3893maylandia_zebraENSMZEP0000500635273.241658.104
ENSG00000162231homo_sapiensENSP0000029417256.058242.6494tetraodon_nigroviridisENSTNIP0000001991570.10153.3333
ENSG00000162231homo_sapiensENSP0000029417215.508912.9241tetraodon_nigroviridisENSTNIP0000000314582.051368.3761
ENSG00000162231homo_sapiensENSP0000029417280.290865.5897paramormyrops_kingsleyaeENSPKIP0000001053779.140164.6497
ENSG00000162231homo_sapiensENSP0000029417279.967766.3974scleropages_formosusENSSFOP0001501163377.952864.7244
ENSG00000162231homo_sapiensENSP0000029417265.589750.2423leptobrachium_leishanenseENSLLEP0000004423668.465452.4452
ENSG00000162231homo_sapiensENSP0000029417227.140519.5477leptobrachium_leishanenseENSLLEP0000004441360.869643.8406
ENSG00000162231homo_sapiensENSP0000029417272.051755.8966leptobrachium_leishanenseENSLLEP0000004066270.458154.6603
ENSG00000162231homo_sapiensENSP0000029417264.943550.0808leptobrachium_leishanenseENSLLEP0000004451666.336651.1551
ENSG00000162231homo_sapiensENSP0000029417275.282759.7738scophthalmus_maximusENSSMAP0000005058769.656255.3064
ENSG00000162231homo_sapiensENSP0000029417277.221359.2892oryzias_melastigmaENSOMEP0000001682771.98855.2711

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding2HDA,IBAHomo_sapiens(9606)Function
GO:0003729enables mRNA binding1IEAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus3IBA,IDA,ISSHomo_sapiens(9606)Component
GO:0005643part_of nuclear pore1IEAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0006406involved_in mRNA export from nucleus2IDA,ISSHomo_sapiens(9606)Process
GO:0010494located_in cytoplasmic stress granule1IEAHomo_sapiens(9606)Component
GO:0015031involved_in protein transport1IEAHomo_sapiens(9606)Process
GO:0016607located_in nuclear speck1IDAHomo_sapiens(9606)Component
GO:0016973involved_in poly(A)+ mRNA export from nucleus1IBAHomo_sapiens(9606)Process
GO:0042272part_of nuclear RNA export factor complex1IPIHomo_sapiens(9606)Component
GO:0042405located_in nuclear inclusion body1IEAHomo_sapiens(9606)Component

Expression