RBPWorld - a comprehensive database of RNA Binding Proteins

Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	CancerFlavivirusesHIVRVSARS-COV-2SINVDengueZika
Drug	N.A.
Main interacting RNAs	mRNA
Moonlighting functions	N.A.
Localizations	Stress granucleP-body
BulkPerturb-seq	DataSet_01_209 DataSet_01_430 DataSet_02_127 DataSet_02_45

Description

Ensembl ID	ENSG00000159217	Gene ID	10642	Accession	28866
Symbol	IGF2BP1	Alias	IMP1;ZBP1;CRDBP;IMP-1;CRD-BP;VICKZ1	Full Name	insulin like growth factor 2 mRNA binding protein 1
Status	Confidence	Length	58761 bases	Strand	Plus strand
Position	17 : 48997385 - 49056145	RNA binding domain	KH_1 , RRM_1
Summary	This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000290341	RRM_1	PF00076	2.8e-15	1
ENSP00000290341	RRM_1	PF00076	2.8e-15	2
ENSP00000290341	KH_1	PF00013	3.1e-55	3
ENSP00000290341	KH_1	PF00013	3.1e-55	4
ENSP00000290341	KH_1	PF00013	3.1e-55	5
ENSP00000290341	KH_1	PF00013	3.1e-55	6
ENSP00000389135	RRM_1	PF00076	1.1e-10	1
ENSP00000389135	KH_1	PF00013	1.4e-41	2
ENSP00000389135	KH_1	PF00013	1.4e-41	3
ENSP00000389135	KH_1	PF00013	1.4e-41	4

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal
25889892	miRNA-196b inhibits cell proliferation and induces apoptosis in HepG2 cells by targeting IGF2BP1.	Magali Rebucci	2015-04-08	Molecular cancer
35565249	IGF2BP1 Promotes Proliferation of Neuroendocrine Neoplasms by Post-Transcriptional Enhancement of EZH2.	Florian Sperling	2022-04-24	Cancers
31727877	Lnc-THOR silencing inhibits human glioma cell survival by activating MAGEA6-AMPK signaling.	Jun Xue	2019-11-14	Cell death & disease
34779401	Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation.	Xiao-Tong Lin	2021-11-15	eLife
33391523	IGF2BP1 overexpression stabilizes PEG10 mRNA in an m6A-dependent manner and promotes endometrial cancer progression.	Lin Zhang	2021-01-01	Theranostics
34638933	RNA Modifications and Epigenetics in Modulation of Lung Cancer and Pulmonary Diseases.	Pai-Chi Teng	2021-09-30	International journal of molecular sciences
30296493	It's complicated… m⁶A-dependent regulation of gene expression in cancer.	M Christina Fitzsimmons	2019-03-01	Biochimica et biophysica acta. Gene regulatory mechanisms
34232536	Interactomes of SARS-CoV-2 and human coronaviruses reveal host factors potentially affecting pathogenesis.	Zhen Chen	2021-09-01	The EMBO journal
29476150	An additional class of m⁶A readers.	I Katherine Zhou	2018-03-01	Nature cell biology
35014946	Insulin-like growth factor 2 mRNA-binding protein 2-stabilized long non-coding RNA Taurine up-regulated gene 1 (TUG1) promotes cisplatin-resistance of colorectal cancer via modulating autophagy.	Cuifeng Xia	2022-02-01	Bioengineered
36771276	Human Milk-Derived Levels of let-7g-5p May Serve as a Diagnostic and Prognostic Marker of Low Milk Supply in Breastfeeding Women.	D Steven Hicks	2023-01-21	Nutrients
36728962	Circular RNA circ_0005667 promotes cisplatin resistance of endometrial carcinoma cells by regulating IGF2BP1 through miR-145-5p.	Guihua Sun	2023-08-01	Anti-cancer drugs
34203267	Insulin-Like Growth Factor 2 mRNA-Binding Protein 1 (IGF2BP1) Is a Prognostic Biomarker and Associated with Chemotherapy Responsiveness in Colorectal Cancer.	Hung-Ming Chen	2021-06-28	International journal of molecular sciences
22427968	Two isoforms of the mRNA binding protein IGF2BP2 are generated by alternative translational initiation.	T T Hang Le	2012-01-01	PloS one
33623109	Predicting dynamic cellular protein-RNA interactions by deep learning using in vivo RNA structures.	Lei Sun	2021-05-01	Cell research
37515119	IGF2BP1-An Oncofetal RNA-Binding Protein Fuels Tumor Virus Propagation.	Markus Glaß	2023-06-24	Viruses
32876513	IGF2BP1 is a targetable SRC/MAPK-dependent driver of invasive growth in ovarian cancer.	Nadine Bley	2021-03-01	RNA biology
34231297	Posttranscriptional regulation of colonic epithelial repair by RNA binding protein IMP1/IGF2BP1.	Priya Chatterji	2021-08-04	EMBO reports

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
IGF2BP1-201	ENST00000290341	8796	577aa	ENSP00000290341
IGF2BP1-205	ENST00000510023	754	No protein	-
IGF2BP1-202	ENST00000431824	1317	438aa	ENSP00000389135
IGF2BP1-206	ENST00000515586	768	No protein	-
IGF2BP1-203	ENST00000499130	568	No protein	-
IGF2BP1-204	ENST00000505562	461	No protein	-

Gene Model

Click here to download ENSG00000159217's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
63758	Odontogenesis	2E-8	20195514
68665	Odontogenesis	7E-16	23704328
69267	Tooth Eruption	2E-14	23704328
77253	Odontogenesis	8E-7	20195514
94364	Body Fat Distribution	3E-8	26833246
100315	Body Fat Distribution	2E-8	26833246

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000159217's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000159217	homo_sapiens	ENSP00000417196	37.9653	21.34	homo_sapiens	ENSP00000290341	26.5165	14.9047
ENSG00000159217	homo_sapiens	ENSP00000263257	26.626	14.2276	homo_sapiens	ENSP00000290341	22.7036	12.1317
ENSG00000159217	homo_sapiens	ENSP00000505796	40.1617	22.6415	homo_sapiens	ENSP00000290341	25.8232	14.5581
ENSG00000159217	homo_sapiens	ENSP00000365439	31.681	18.319	homo_sapiens	ENSP00000290341	25.4766	14.7314
ENSG00000159217	homo_sapiens	ENSP00000448762	42.2652	24.0331	homo_sapiens	ENSP00000290341	26.5165	15.078
ENSG00000159217	homo_sapiens	ENSP00000371634	78.2972	65.2755	homo_sapiens	ENSP00000290341	81.2825	67.7643
ENSG00000159217	homo_sapiens	ENSP00000359804	29.8137	16.7702	homo_sapiens	ENSP00000290341	33.2756	18.7175
ENSG00000159217	homo_sapiens	ENSP00000258729	83.247	73.057	homo_sapiens	ENSP00000290341	83.5355	73.3102
ENSG00000159217	homo_sapiens	ENSP00000318177	33.9161	17.6573	homo_sapiens	ENSP00000290341	33.6222	17.5043
ENSG00000159217	homo_sapiens	ENSP00000305556	42.4157	24.4382	homo_sapiens	ENSP00000290341	26.1698	15.078
ENSG00000159217	homo_sapiens	ENSP00000438875	26.6272	13.8067	homo_sapiens	ENSP00000290341	23.3969	12.1317
ENSG00000159217	homo_sapiens	ENSP00000471146	27.7108	16.1981	homo_sapiens	ENSP00000290341	35.8752	20.9705

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000159217	homo_sapiens	ENSP00000290341	100	100	nomascus_leucogenys	ENSNLEP00000003444	100	100
ENSG00000159217	homo_sapiens	ENSP00000290341	100	99.8267	pan_paniscus	ENSPPAP00000034839	100	99.8267
ENSG00000159217	homo_sapiens	ENSP00000290341	100	100	pongo_abelii	ENSPPYP00000010002	100	100
ENSG00000159217	homo_sapiens	ENSP00000290341	100	99.8267	pan_troglodytes	ENSPTRP00000015920	100	99.8267
ENSG00000159217	homo_sapiens	ENSP00000290341	100	100	gorilla_gorilla	ENSGGOP00000042111	100	100
ENSG00000159217	homo_sapiens	ENSP00000290341	92.0277	88.7348	ornithorhynchus_anatinus	ENSOANP00000023395	94.3162	90.9414
ENSG00000159217	homo_sapiens	ENSP00000290341	98.9601	97.4003	sarcophilus_harrisii	ENSSHAP00000016760	98.9601	97.4003
ENSG00000159217	homo_sapiens	ENSP00000290341	65.338	63.7782	notamacropus_eugenii	ENSMEUP00000001967	70.2048	68.5289
ENSG00000159217	homo_sapiens	ENSP00000290341	68.1109	67.9376	choloepus_hoffmanni	ENSCHOP00000002077	81.7048	81.4969
ENSG00000159217	homo_sapiens	ENSP00000290341	96.7071	96.1872	dasypus_novemcinctus	ENSDNOP00000005283	97.7233	97.1979
ENSG00000159217	homo_sapiens	ENSP00000290341	85.4419	85.4419	erinaceus_europaeus	ENSEEUP00000009996	85.4419	85.4419
ENSG00000159217	homo_sapiens	ENSP00000290341	74.1768	72.617	echinops_telfairi	ENSETEP00000002764	82.9457	81.2016
ENSG00000159217	homo_sapiens	ENSP00000290341	100	100	callithrix_jacchus	ENSCJAP00000013583	100	100
ENSG00000159217	homo_sapiens	ENSP00000290341	98.0936	97.747	cercocebus_atys	ENSCATP00000038021	97.084	96.741
ENSG00000159217	homo_sapiens	ENSP00000290341	100	100	macaca_fascicularis	ENSMFAP00000003806	100	100
ENSG00000159217	homo_sapiens	ENSP00000290341	100	100	macaca_mulatta	ENSMMUP00000015143	100	100
ENSG00000159217	homo_sapiens	ENSP00000290341	98.0936	97.747	macaca_nemestrina	ENSMNEP00000020045	97.084	96.741
ENSG00000159217	homo_sapiens	ENSP00000290341	96.5338	96.5338	papio_anubis	ENSPANP00000020122	100	100
ENSG00000159217	homo_sapiens	ENSP00000290341	98.0936	97.747	mandrillus_leucophaeus	ENSMLEP00000006223	97.084	96.741
ENSG00000159217	homo_sapiens	ENSP00000290341	96.5338	96.3605	tursiops_truncatus	ENSTTRP00000006811	96.5338	96.3605
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.8267	vulpes_vulpes	ENSVVUP00000004386	99.8267	99.8267
ENSG00000159217	homo_sapiens	ENSP00000290341	99.4801	99.3068	mus_spretus	MGP_SPRETEiJ_P0030818	99.4801	99.3068
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.6534	equus_asinus	ENSEASP00005000374	99.8267	99.6534
ENSG00000159217	homo_sapiens	ENSP00000290341	99.6534	99.4801	capra_hircus	ENSCHIP00000025650	99.6534	99.4801
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.6534	loxodonta_africana	ENSLAFP00000001714	99.8267	99.6534
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.8267	panthera_leo	ENSPLOP00000029041	99.8267	99.8267
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.8267	ailuropoda_melanoleuca	ENSAMEP00000005385	77.4194	77.4194
ENSG00000159217	homo_sapiens	ENSP00000290341	99.6534	99.4801	bos_indicus_hybrid	ENSBIXP00005028304	99.6534	99.4801
ENSG00000159217	homo_sapiens	ENSP00000290341	98.6135	98.2669	oryctolagus_cuniculus	ENSOCUP00000003814	99.8246	99.4737
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.6534	equus_caballus	ENSECAP00000026537	99.8267	99.6534
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.8267	canis_lupus_familiaris	ENSCAFP00845014586	99.8267	99.8267
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.8267	panthera_pardus	ENSPPRP00000015454	99.8267	99.8267
ENSG00000159217	homo_sapiens	ENSP00000290341	99.6534	99.6534	marmota_marmota_marmota	ENSMMMP00000000668	99.6534	99.6534
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.6534	balaenoptera_musculus	ENSBMSP00010023363	99.8267	99.6534
ENSG00000159217	homo_sapiens	ENSP00000290341	94.4541	93.5875	cavia_porcellus	ENSCPOP00000014618	99.6344	98.7203
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.8267	felis_catus	ENSFCAP00000002259	99.8267	99.8267
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.8267	ursus_americanus	ENSUAMP00000030329	99.8267	99.8267
ENSG00000159217	homo_sapiens	ENSP00000290341	99.1334	97.5737	monodelphis_domestica	ENSMODP00000015362	87.4618	86.0856
ENSG00000159217	homo_sapiens	ENSP00000290341	74.87	74.6967	bison_bison_bison	ENSBBBP00000025859	99.5392	99.3088
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.6534	monodon_monoceros	ENSMMNP00015030302	99.8267	99.6534
ENSG00000159217	homo_sapiens	ENSP00000290341	99.6534	99.6534	sus_scrofa	ENSSSCP00000020836	99.6534	99.6534
ENSG00000159217	homo_sapiens	ENSP00000290341	93.9341	93.2409	microcebus_murinus	ENSMICP00000012152	97.6577	96.9369
ENSG00000159217	homo_sapiens	ENSP00000290341	62.7383	61.6984	microcebus_murinus	ENSMICP00000046433	92.3469	90.8163
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.3068	octodon_degus	ENSODEP00000023170	99.8267	99.3068
ENSG00000159217	homo_sapiens	ENSP00000290341	73.3102	69.1508	octodon_degus	ENSODEP00000019693	85.8012	80.9331
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	98.9601	jaculus_jaculus	ENSJJAP00000001817	99.8267	98.9601
ENSG00000159217	homo_sapiens	ENSP00000290341	99.6534	99.4801	ovis_aries_rambouillet	ENSOARP00020029227	99.6534	99.4801
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.6534	ursus_maritimus	ENSUMAP00000021494	99.8267	99.6534
ENSG00000159217	homo_sapiens	ENSP00000290341	85.2686	84.922	ochotona_princeps	ENSOPRP00000009328	94.9807	94.5946
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.6534	delphinapterus_leucas	ENSDLEP00000006581	99.8267	99.6534
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.8267	physeter_catodon	ENSPCTP00005006277	99.8267	99.8267
ENSG00000159217	homo_sapiens	ENSP00000290341	99.4801	99.3068	mus_caroli	MGP_CAROLIEiJ_P0029397	99.4801	99.3068
ENSG00000159217	homo_sapiens	ENSP00000290341	99.4801	99.3068	mus_musculus	ENSMUSP00000013559	99.4801	99.3068
ENSG00000159217	homo_sapiens	ENSP00000290341	92.0277	91.3345	dipodomys_ordii	ENSDORP00000013516	96.7213	95.9927
ENSG00000159217	homo_sapiens	ENSP00000290341	84.2288	83.1889	mustela_putorius_furo	ENSMPUP00000015248	96.0474	94.8617
ENSG00000159217	homo_sapiens	ENSP00000290341	97.9203	97.747	aotus_nancymaae	ENSANAP00000009251	96.9125	96.741
ENSG00000159217	homo_sapiens	ENSP00000290341	97.9203	97.747	saimiri_boliviensis_boliviensis	ENSSBOP00000008158	96.9125	96.741
ENSG00000159217	homo_sapiens	ENSP00000290341	71.5771	71.2305	vicugna_pacos	ENSVPAP00000007122	75.7798	75.4128
ENSG00000159217	homo_sapiens	ENSP00000290341	100	100	chlorocebus_sabaeus	ENSCSAP00000015561	100	100
ENSG00000159217	homo_sapiens	ENSP00000290341	80.5893	80.4159	tupaia_belangeri	ENSTBEP00000003708	81.5789	81.4035
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.6534	phocoena_sinus	ENSPSNP00000022395	99.8267	99.6534
ENSG00000159217	homo_sapiens	ENSP00000290341	96.8804	96.8804	camelus_dromedarius	ENSCDRP00005024491	99.6435	99.6435
ENSG00000159217	homo_sapiens	ENSP00000290341	100	100	carlito_syrichta	ENSTSYP00000032946	100	100
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.8267	panthera_tigris_altaica	ENSPTIP00000013646	99.8267	99.8267
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.6534	rattus_norvegicus	ENSRNOP00000008139	99.8267	99.6534
ENSG00000159217	homo_sapiens	ENSP00000290341	92.201	91.1612	prolemur_simus	ENSPSMP00000029427	98.155	97.048
ENSG00000159217	homo_sapiens	ENSP00000290341	100	100	microtus_ochrogaster	ENSMOCP00000010058	100	100
ENSG00000159217	homo_sapiens	ENSP00000290341	54.766	54.5927	sorex_araneus	ENSSARP00000011918	61.0039	60.8108
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.6534	peromyscus_maniculatus_bairdii	ENSPEMP00000025594	99.8267	99.6534
ENSG00000159217	homo_sapiens	ENSP00000290341	99.6534	99.3068	bos_mutus	ENSBMUP00000000625	99.6534	99.3068
ENSG00000159217	homo_sapiens	ENSP00000290341	99.4801	98.9601	mus_spicilegus	ENSMSIP00000022604	99.4801	98.9601
ENSG00000159217	homo_sapiens	ENSP00000290341	67.9376	66.3778	cricetulus_griseus_chok1gshd	ENSCGRP00001003050	95.6098	93.4146
ENSG00000159217	homo_sapiens	ENSP00000290341	85.0953	82.149	cricetulus_griseus_chok1gshd	ENSCGRP00001005146	89.9267	86.8132
ENSG00000159217	homo_sapiens	ENSP00000290341	100	100	cricetulus_griseus_chok1gshd	ENSCGRP00001000354	100	100
ENSG00000159217	homo_sapiens	ENSP00000290341	79.7227	79.7227	pteropus_vampyrus	ENSPVAP00000001622	79.5848	79.5848
ENSG00000159217	homo_sapiens	ENSP00000290341	68.9775	68.4575	myotis_lucifugus	ENSMLUP00000015400	98.0296	97.2906
ENSG00000159217	homo_sapiens	ENSP00000290341	62.9116	61.3518	myotis_lucifugus	ENSMLUP00000021986	92.602	90.3061
ENSG00000159217	homo_sapiens	ENSP00000290341	98.9601	97.5737	vombatus_ursinus	ENSVURP00010010025	98.9601	97.5737
ENSG00000159217	homo_sapiens	ENSP00000290341	99.6534	99.3068	rhinolophus_ferrumequinum	ENSRFEP00010033031	99.6534	99.3068
ENSG00000159217	homo_sapiens	ENSP00000290341	95.8406	95.3206	neovison_vison	ENSNVIP00000008066	95.8406	95.3206
ENSG00000159217	homo_sapiens	ENSP00000290341	99.6534	99.4801	bos_taurus	ENSBTAP00000015586	99.6534	99.4801
ENSG00000159217	homo_sapiens	ENSP00000290341	99.6534	98.7868	heterocephalus_glaber_female	ENSHGLP00000014656	99.6534	98.7868
ENSG00000159217	homo_sapiens	ENSP00000290341	98.0936	97.747	rhinopithecus_bieti	ENSRBIP00000023659	97.084	96.741
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.8267	canis_lupus_dingo	ENSCAFP00020030005	99.8267	99.8267
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.6534	sciurus_vulgaris	ENSSVLP00005026213	99.8267	99.6534
ENSG00000159217	homo_sapiens	ENSP00000290341	98.7868	97.4003	phascolarctos_cinereus	ENSPCIP00000017346	98.9583	97.5694
ENSG00000159217	homo_sapiens	ENSP00000290341	91.3345	90.9879	procavia_capensis	ENSPCAP00000015550	91.8118	91.4634
ENSG00000159217	homo_sapiens	ENSP00000290341	100	100	nannospalax_galili	ENSNGAP00000014348	100	100
ENSG00000159217	homo_sapiens	ENSP00000290341	96.3605	95.4939	bos_grunniens	ENSBGRP00000035932	95.2055	94.3493
ENSG00000159217	homo_sapiens	ENSP00000290341	99.3068	98.4402	chinchilla_lanigera	ENSCLAP00000023092	99.3068	98.4402
ENSG00000159217	homo_sapiens	ENSP00000290341	99.6534	99.4801	cervus_hanglu_yarkandensis	ENSCHYP00000007033	99.6534	99.4801
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.6534	catagonus_wagneri	ENSCWAP00000029462	99.8267	99.6534
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.8267	ictidomys_tridecemlineatus	ENSSTOP00000009560	99.8267	99.8267
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.6534	otolemur_garnettii	ENSOGAP00000001134	99.8267	99.6534
ENSG00000159217	homo_sapiens	ENSP00000290341	96.7071	96.7071	cebus_imitator	ENSCCAP00000027974	99.6429	99.6429
ENSG00000159217	homo_sapiens	ENSP00000290341	99.6534	99.6534	urocitellus_parryii	ENSUPAP00010007601	99.6534	99.6534
ENSG00000159217	homo_sapiens	ENSP00000290341	99.6534	99.3068	moschus_moschiferus	ENSMMSP00000033238	99.6534	99.3068
ENSG00000159217	homo_sapiens	ENSP00000290341	98.0936	97.747	rhinopithecus_roxellana	ENSRROP00000031838	97.084	96.741
ENSG00000159217	homo_sapiens	ENSP00000290341	32.409	25.3033	mus_pahari	MGP_PahariEiJ_P0036110	33.8156	26.4014
ENSG00000159217	homo_sapiens	ENSP00000290341	99.8267	99.6534	propithecus_coquereli	ENSPCOP00000002112	99.8267	99.6534
ENSG00000159217	homo_sapiens	ENSP00000290341	20.104	9.35875	caenorhabditis_elegans	Y119D3B.17.2	26.8519	12.5
ENSG00000159217	homo_sapiens	ENSP00000290341	15.2513	8.31889	caenorhabditis_elegans	Y59A8B.10d.1	21.1031	11.5108
ENSG00000159217	homo_sapiens	ENSP00000290341	26.5165	13.6915	caenorhabditis_elegans	C36E6.1b.1	23.869	12.3245
ENSG00000159217	homo_sapiens	ENSP00000290341	25.8232	12.825	caenorhabditis_elegans	M01A10.1.1	25.4266	12.628
ENSG00000159217	homo_sapiens	ENSP00000290341	44.5407	27.0364	caenorhabditis_elegans	M88.5c.1	30.0937	18.267
ENSG00000159217	homo_sapiens	ENSP00000290341	26.5165	14.9047	caenorhabditis_elegans	C12D8.1b.1	25.0409	14.0753
ENSG00000159217	homo_sapiens	ENSP00000290341	26.1698	14.5581	drosophila_melanogaster	FBpp0293521	26.3525	14.6597
ENSG00000159217	homo_sapiens	ENSP00000290341	22.0104	10.3986	drosophila_melanogaster	FBpp0306419	16.2821	7.69231
ENSG00000159217	homo_sapiens	ENSP00000290341	51.9931	36.0485	drosophila_melanogaster	FBpp0293680	47.0219	32.6019
ENSG00000159217	homo_sapiens	ENSP00000290341	30.6759	15.4246	drosophila_melanogaster	FBpp0428307	22.2083	11.1669
ENSG00000159217	homo_sapiens	ENSP00000290341	20.4506	11.2652	ciona_intestinalis	ENSCINP00000001984	33.0532	18.2073
ENSG00000159217	homo_sapiens	ENSP00000290341	17.851	7.97227	ciona_intestinalis	ENSCINP00000025950	36.2676	16.1972
ENSG00000159217	homo_sapiens	ENSP00000290341	62.2184	46.2738	ciona_intestinalis	ENSCINP00000008726	60.7445	45.1777
ENSG00000159217	homo_sapiens	ENSP00000290341	18.0243	10.052	ciona_intestinalis	ENSCINP00000019569	32.7044	18.239
ENSG00000159217	homo_sapiens	ENSP00000290341	16.1179	7.79896	ciona_intestinalis	ENSCINP00000030435	35.3612	17.1103
ENSG00000159217	homo_sapiens	ENSP00000290341	24.6101	12.305	astyanax_mexicanus	ENSAMXP00000028943	45.2229	22.6115
ENSG00000159217	homo_sapiens	ENSP00000290341	87.8683	84.4021	chrysemys_picta_bellii	ENSCPBP00000039669	91.0233	87.4327
ENSG00000159217	homo_sapiens	ENSP00000290341	95.1473	92.0277	sphenodon_punctatus	ENSSPUP00000008436	95.6446	92.5087
ENSG00000159217	homo_sapiens	ENSP00000290341	89.0815	86.6551	crocodylus_porosus	ENSCPRP00005010262	95.0092	92.4214
ENSG00000159217	homo_sapiens	ENSP00000290341	74.1768	72.0971	laticauda_laticaudata	ENSLLTP00000004930	97.2727	94.5455
ENSG00000159217	homo_sapiens	ENSP00000290341	95.1473	91.8544	notechis_scutatus	ENSNSUP00000009713	95.4783	92.1739
ENSG00000159217	homo_sapiens	ENSP00000290341	95.1473	91.8544	pseudonaja_textilis	ENSPTXP00000020060	95.4783	92.1739
ENSG00000159217	homo_sapiens	ENSP00000290341	97.0537	94.2808	anas_platyrhynchos_platyrhynchos	ENSAPLP00000025875	97.2222	94.4444
ENSG00000159217	homo_sapiens	ENSP00000290341	96.8804	94.4541	gallus_gallus	ENSGALP00010037058	91.9408	89.6382
ENSG00000159217	homo_sapiens	ENSP00000290341	88.0416	85.4419	meleagris_gallopavo	ENSMGAP00000002112	93.7269	90.9594
ENSG00000159217	homo_sapiens	ENSP00000290341	97.0537	94.2808	anolis_carolinensis	ENSACAP00000006134	97.2222	94.4444
ENSG00000159217	homo_sapiens	ENSP00000290341	97.227	94.4541	naja_naja	ENSNNAP00000014318	97.3958	94.6181
ENSG00000159217	homo_sapiens	ENSP00000290341	97.0537	94.2808	podarcis_muralis	ENSPMRP00000020098	97.2222	94.4444
ENSG00000159217	homo_sapiens	ENSP00000290341	67.591	61.3518	geospiza_fortis	ENSGFOP00000005172	82.9787	75.3191
ENSG00000159217	homo_sapiens	ENSP00000290341	93.5875	88.0416	taeniopygia_guttata	ENSTGUP00000016545	94.7368	89.1228
ENSG00000159217	homo_sapiens	ENSP00000290341	97.0537	94.1075	salvator_merianae	ENSSMRP00000028387	97.2222	94.2708
ENSG00000159217	homo_sapiens	ENSP00000290341	76.0832	71.2305	pelodiscus_sinensis	ENSPSIP00000005576	87.6247	82.0359
ENSG00000159217	homo_sapiens	ENSP00000290341	94.2808	91.8544	gopherus_evgoodei	ENSGEVP00005025714	96.7971	94.3061
ENSG00000159217	homo_sapiens	ENSP00000290341	94.4541	91.6811	chelonoidis_abingdonii	ENSCABP00000003647	97.3214	94.4643
ENSG00000159217	homo_sapiens	ENSP00000290341	72.617	69.6707	struthio_camelus_australis	ENSSCUP00000011600	92.6991	88.938
ENSG00000159217	homo_sapiens	ENSP00000290341	97.0537	94.2808	anser_brachyrhynchus	ENSABRP00000000180	97.2222	94.4444
ENSG00000159217	homo_sapiens	ENSP00000290341	96.8804	94.6274	strigops_habroptila	ENSSHBP00005016634	97.0486	94.7917
ENSG00000159217	homo_sapiens	ENSP00000290341	95.4939	92.201	terrapene_carolina_triunguis	ENSTMTP00000010967	95	91.7241
ENSG00000159217	homo_sapiens	ENSP00000290341	17.331	9.35875	ciona_savignyi	ENSCSAVP00000004755	47.619	25.7143
ENSG00000159217	homo_sapiens	ENSP00000290341	9.70537	4.85269	ciona_savignyi	ENSCSAVP00000007214	45.9016	22.9508
ENSG00000159217	homo_sapiens	ENSP00000290341	61.6984	44.8873	ciona_savignyi	ENSCSAVP00000018813	61.3793	44.6552
ENSG00000159217	homo_sapiens	ENSP00000290341	17.851	8.4922	ciona_savignyi	ENSCSAVP00000007375	33.3333	15.8576
ENSG00000159217	homo_sapiens	ENSP00000290341	23.3969	12.9983	ciona_savignyi	ENSCSAVP00000005505	24.9538	13.8632
ENSG00000159217	homo_sapiens	ENSP00000290341	14.0381	8.14558	ciona_savignyi	ENSCSAVP00000005450	23.9645	13.9053
ENSG00000159217	homo_sapiens	ENSP00000290341	97.0537	94.4541	aquila_chrysaetos_chrysaetos	ENSACCP00020008814	97.2222	94.6181
ENSG00000159217	homo_sapiens	ENSP00000290341	96.8804	94.4541	coturnix_japonica	ENSCJPP00005024576	97.0486	94.6181

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000932	located_in P-body	1	IDA	Homo_sapiens(9606)	Component
GO:0001817	involved_in regulation of cytokine production	1	IC	Homo_sapiens(9606)	Process
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0003729	enables mRNA binding	1	IDA	Homo_sapiens(9606)	Function
GO:0003730	enables mRNA 3-UTR binding	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	1	IBA	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0005737	is_active_in cytoplasm	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005829	is_active_in cytosol	3	IBA,IDA,TAS	Homo_sapiens(9606)	Component
GO:0007399	involved_in nervous system development	1	IBA	Homo_sapiens(9606)	Process
GO:0010468	involved_in regulation of gene expression	1	IBA	Homo_sapiens(9606)	Process
GO:0010494	located_in cytoplasmic stress granule	1	IDA	Homo_sapiens(9606)	Component
GO:0010610	involved_in regulation of mRNA stability involved in response to stress	1	IMP	Homo_sapiens(9606)	Process
GO:0017148	involved_in negative regulation of translation	1	IDA	Homo_sapiens(9606)	Process
GO:0022013	involved_in pallium cell proliferation in forebrain	1	IEA	Homo_sapiens(9606)	Process
GO:0030027	located_in lamellipodium	1	IEA	Homo_sapiens(9606)	Component
GO:0030175	located_in filopodium	1	IEA	Homo_sapiens(9606)	Component
GO:0030426	located_in growth cone	1	IEA	Homo_sapiens(9606)	Component
GO:0043025	located_in neuronal cell body	1	IEA	Homo_sapiens(9606)	Component
GO:0043197	located_in dendritic spine	1	IEA	Homo_sapiens(9606)	Component
GO:0045182	enables translation regulator activity	1	IDA	Homo_sapiens(9606)	Function
GO:0048027	enables mRNA 5-UTR binding	1	IDA	Homo_sapiens(9606)	Function
GO:0048471	located_in perinuclear region of cytoplasm	1	IEA	Homo_sapiens(9606)	Component
GO:0051028	involved_in mRNA transport	1	IEA	Homo_sapiens(9606)	Process
GO:0070934	involved_in CRD-mediated mRNA stabilization	1	IDA	Homo_sapiens(9606)	Process
GO:0070937	part_of CRD-mediated mRNA stability complex	2	IDA,IPI	Homo_sapiens(9606)	Component
GO:0097150	involved_in neuronal stem cell population maintenance	1	IEA	Homo_sapiens(9606)	Process
GO:0140059	involved_in dendrite arborization	1	IEA	Homo_sapiens(9606)	Process
GO:1900152	involved_in negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	1	IDA	Homo_sapiens(9606)	Process
GO:1990247	enables N6-methyladenosine-containing RNA binding	1	IDA	Homo_sapiens(9606)	Function
GO:1990904	part_of ribonucleoprotein complex	1	IDA	Homo_sapiens(9606)	Component
GO:2000767	involved_in positive regulation of cytoplasmic translation	1	IDA	Homo_sapiens(9606)	Process

Welcome to

RBP World!

Functions and Diseases

Description

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression