Ensembl ID ENSG00000159217 Gene ID 10642 Accession 28866
Gene Symbol IGF2BP1 Alias IMP1;ZBP1;CRDBP;IMP-1;CRD-BP;VICKZ1 Full Name insulin like growth factor 2 mRNA binding protein 1
Position 17 : 48997385 - 49056145 Length 58761 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

ENSG00000159217 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000159217 IGF2BP1 6.01 5.47e-54 HNSC
ENSG00000159217 IGF2BP1 6.75 1.17e-19 BLCA
ENSG00000159217 IGF2BP1 3.03 1.15e-47 BRCA
ENSG00000159217 IGF2BP1 4.41 7.32e-23 COAD
ENSG00000159217 IGF2BP1 -2.6 2.46e-14 KICH
ENSG00000159217 IGF2BP1 6.07 2.81e-11 READ
ENSG00000159217 IGF2BP1 7.05 5.72e-84 LUSC
ENSG00000159217 IGF2BP1 7.00 3.39e-65 LIHC
ENSG00000159217 IGF2BP1 6.03 1.58e-30 STAD
ENSG00000159217 IGF2BP1 4.31 1.20e-18 UCEC
ENSG00000159217 IGF2BP1 6.60 7.97e-54 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000159217 IGF2BP1 cancer 10190901
ENSG00000159217 IGF2BP1 breast cancers 10850408
ENSG00000159217 IGF2BP1 cancer 11641779
ENSG00000159217 IGF2BP1 malignant mesenchymal tumors 11745432
ENSG00000159217 IGF2BP1 tumors 12532419
ENSG00000159217 IGF2BP1 tumor 12894594
ENSG00000159217 IGF2BP1 tumors 14729626
ENSG00000159217 IGF2BP1 ovarian cancer 14767552
ENSG00000159217 IGF2BP1 tumors 15159028
ENSG00000159217 IGF2BP1 tumors 15355996
ENSG00000159217 IGF2BP1 tumors 15574765
ENSG00000159217 IGF2BP1 cancer 15601260
ENSG00000159217 IGF2BP1 cancer 15769738
ENSG00000159217 IGF2BP1 colorectal cancer 16778892
ENSG00000159217 IGF2BP1 cancers 17264115
ENSG00000159217 IGF2BP1 colon cancer 17415713
ENSG00000159217 IGF2BP1 tumor 17878234
ENSG00000159217 IGF2BP1 breast cancer 18490442
ENSG00000159217 IGF2BP1 breast-cancer 19461076
ENSG00000159217 IGF2BP1 Tumor 19661680
ENSG00000159217 IGF2BP1 soft tissue tumors 21414819
ENSG00000159217 IGF2BP1 tumors 21779431
ENSG00000159217 IGF2BP1 tumor 21853155
ENSG00000159217 IGF2BP1 cancer 21981993
ENSG00000159217 IGF2BP1 breast cancer 22266909
ENSG00000159217 IGF2BP1 tumor 22279049
ENSG00000159217 IGF2BP1 tumor 22983196
ENSG00000159217 IGF2BP1 tumor 23038779
ENSG00000159217 IGF2BP1 cancer 23069990
ENSG00000159217 IGF2BP1 cancers 23072359
ENSG00000159217 IGF2BP1 tumor 23677615
ENSG00000159217 IGF2BP1 tumors 23930849
ENSG00000159217 IGF2BP1 liver cancer 24395596
ENSG00000159217 IGF2BP1 cancer 24457969
ENSG00000159217 IGF2BP1 tumors 24468749
ENSG00000159217 IGF2BP1 tumour 24622399
ENSG00000159217 IGF2BP1 tumour 24632613
ENSG00000159217 IGF2BP1 tumours 24704827
ENSG00000159217 IGF2BP1 tumor 24814803
ENSG00000159217 IGF2BP1 tumor 24965446
ENSG00000159217 IGF2BP1 cancers 25068994
ENSG00000159217 IGF2BP1 tumor 25114832
ENSG00000159217 IGF2BP1 cancer 25588836
ENSG00000159217 IGF2BP1 tumors 25753434
ENSG00000159217 IGF2BP1 tumor 25861239
ENSG00000159217 IGF2BP1 Breast Tumor 25861986
ENSG00000159217 IGF2BP1 cancers 25878333
ENSG00000159217 IGF2BP1 tumor 25889892
ENSG00000159217 IGF2BP1 cancers 26244988
ENSG00000159217 IGF2BP1 tumour 26332146
ENSG00000159217 IGF2BP1 tumor 26547929
ENSG00000159217 IGF2BP1 tumor 26561465
ENSG00000159217 IGF2BP1 tumor 26692944
ENSG00000159217 IGF2BP1 cancer 26840568
ENSG00000159217 IGF2BP1 cancers 26852652
ENSG00000159217 IGF2BP1 tumor 26917013
ENSG00000159217 IGF2BP1 colorectal cancer 27036131
ENSG00000159217 IGF2BP1 non-small cell lung cancer 27158341
ENSG00000159217 IGF2BP1 tumors 27239736
ENSG00000159217 IGF2BP1 tumour 27499093
ENSG00000159217 IGF2BP1 cervical cancer 27588393
ENSG00000159217 IGF2BP1 tumors 27655671
ENSG00000159217 IGF2BP1 tumors 27799869
ENSG00000159217 IGF2BP1 tumours 27966453
ENSG00000159217 IGF2BP1 tumor 28011484
ENSG00000159217 IGF2BP1 tumour 28085133
ENSG00000159217 IGF2BP1 cancers 28147274
ENSG00000159217 IGF2BP1 cancers 28182633
ENSG00000159217 IGF2BP1 Cancer 28381175
ENSG00000159217 IGF2BP1 tumor 28486549
ENSG00000159217 IGF2BP1 cancer 28497370
ENSG00000159217 IGF2BP1 cancer 28673325
ENSG00000159217 IGF2BP1 tumor 28677801
ENSG00000159217 IGF2BP1 ovarian cancer 28685895
ENSG00000159217 IGF2BP1 AML 28693523
ENSG00000159217 IGF2BP1 gastric cancer 28768706
ENSG00000159217 IGF2BP1 tumor 28787442
ENSG00000159217 IGF2BP1 cancer 28798901
ENSG00000159217 IGF2BP1 bladder cancer 28882129
ENSG00000159217 IGF2BP1 cancer 29026081
ENSG00000159217 IGF2BP1 tumor 29236673
ENSG00000159217 IGF2BP1 tumor 29383160
ENSG00000159217 IGF2BP1 cervical cancer 29399123
ENSG00000159217 IGF2BP1 ovarian cancer 29660014
ENSG00000159217 IGF2BP1 tumor 29721152
ENSG00000159217 IGF2BP1 tumor 29753746
ENSG00000159217 IGF2BP1 cancer 29954406
ENSG00000159217 IGF2BP1 breast cancer 29987229
ENSG00000159217 IGF2BP1 tumor 30220021
ENSG00000159217 IGF2BP1 cancer 30353165
ENSG00000159217 IGF2BP1 tumor 30371874
ENSG00000159217 IGF2BP1 tumor 30558204
ENSG00000159217 IGF2BP1 colorectal cancer 30569605
ENSG00000159217 IGF2BP1 tumor 30700831
ENSG00000159217 IGF2BP1 tumor 30718359
ENSG00000159217 IGF2BP1 tumor 30936459
ENSG00000159217 IGF2BP1 cancer 31061170
ENSG00000159217 IGF2BP1 cancer 31178721
ENSG00000159217 IGF2BP1 tumor 31427725
ENSG00000159217 IGF2BP1 tumor 31440515
ENSG00000159217 IGF2BP1 cancer 31570709
ENSG00000159217 IGF2BP1 Tumour 31615341
ENSG00000159217 IGF2BP1 pancreatic cancer 31686763
ENSG00000159217 IGF2BP1 cancer 31727877
ENSG00000159217 IGF2BP1 cancers 31768017
ENSG00000159217 IGF2BP1 cancers 9801297
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000159217 IGF2BP1 MESO 0.00011 high
ENSG00000159217 IGF2BP1 SARC 0.01 high
ENSG00000159217 IGF2BP1 STAD 0.0059 high
ENSG00000159217 IGF2BP1 CHOL 0.011 high
ENSG00000159217 IGF2BP1 UVM 0.011 high
ENSG00000159217 IGF2BP1 PAAD 0.00015 high
ENSG00000159217 IGF2BP1 HNSC 0.0066 high
ENSG00000159217 IGF2BP1 READ 0.037 high
ENSG00000159217 IGF2BP1 KICH 0.00092 high
ENSG00000159217 IGF2BP1 THYM 0.03 low
ENSG00000159217 IGF2BP1 BRCA 0.00028 high
ENSG00000159217 IGF2BP1 COAD 0.008 high
ENSG00000159217 IGF2BP1 DLBC 0.021 low
ENSG00000159217 IGF2BP1 KIRC 0.0014 high
ENSG00000159217 IGF2BP1 GBM 0.014 high
ENSG00000159217 IGF2BP1 LIHC 0.003 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000159217 IGF2BP1 SKCM Amp 1.363297 0.142294 0.532421 0.267030
ENSG00000159217 IGF2BP1 BRCA Amp 33.501013 0.444949 0.911683 0.304630