RBP Type	Canonical_RBPs
Diseases	CancerSARS-COV-OC43FlavivirusesHIVRVSARS-COV-2SINVDengueZika
Drug	Drug
Main interacting RNAs	rRNA
Moonlighting functions	Metabolic enzyme
Localizations	Stress granucleP-body
BulkPerturb-seq	DataSet_02_106

Ensembl ID	ENSG00000149273	Gene ID	6188	Accession	10420
Symbol	RPS3	Alias	S3;uS3	Full Name	ribosomal protein S3
Status	Confidence	Length	22763 bases	Strand	Plus strand
Position	11 : 75399518 - 75422280	RNA binding domain	KH_2 , Ribosomal_S3_C
Summary	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. The protein belongs to the S3P family of ribosomal proteins. Studies of the mouse and rat proteins have demonstrated that the protein has an extraribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus. Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed. This gene is co-transcribed with the small nucleolar RNA genes U15A and U15B, which are located in its first and fifth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000433155	KH_2	PF07650	1.9e-11	1
ENSP00000437105	KH_2	PF07650	2.2e-11	1
ENSP00000431737	KH_2	PF07650	2.7e-11	1
ENSP00000436335	KH_2	PF07650	4.4e-11	1
ENSP00000433821	KH_2	PF07650	8.8e-11	1
ENSP00000433821	Ribosomal_S3_C	PF00189	5.8e-23	2
ENSP00000434643	KH_2	PF07650	8.8e-11	1
ENSP00000434643	Ribosomal_S3_C	PF00189	5.8e-23	2
ENSP00000436971	KH_2	PF07650	8.8e-11	1
ENSP00000436971	Ribosomal_S3_C	PF00189	5.8e-23	2
ENSP00000278572	KH_2	PF07650	4.2e-10	1
ENSP00000278572	Ribosomal_S3_C	PF00189	6.8e-23	2
ENSP00000432542	KH_2	PF07650	6.7e-10	1
ENSP00000431834	KH_2	PF07650	1.2e-09	1
ENSP00000433421	KH_2	PF07650	3.9e-09	1
ENSP00000433421	Ribosomal_S3_C	PF00189	5.5e-23	2
ENSP00000435457	KH_2	PF07650	1.1e-08	1
ENSP00000436556	Ribosomal_S3_C	PF00189	3e-20	1
ENSP00000416745	Ribosomal_S3_C	PF00189	6.2e-17	1
ENSP00000435566	Ribosomal_S3_C	PF00189	2e-08	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
RPS3-212	ENST00000529173	1373	No protein	-
RPS3-210	ENST00000528439	473	91aa	ENSP00000432542
RPS3-217	ENST00000531188	2059	243aa	ENSP00000434643
RPS3-214	ENST00000530164	1878	117aa	ENSP00000433155
RPS3-216	ENST00000530721	796	44aa	ENSP00000432458
RPS3-202	ENST00000422465	903	103aa	ENSP00000416745
RPS3-201	ENST00000278572	907	259aa	ENSP00000278572
RPS3-218	ENST00000532872	737	115aa	ENSP00000431834
RPS3-219	ENST00000534440	564	158aa	ENSP00000436335
RPS3-209	ENST00000527446	1306	243aa	ENSP00000436971
RPS3-207	ENST00000526608	710	231aa	ENSP00000433421
RPS3-208	ENST00000527273	390	128aa	ENSP00000435457
RPS3-203	ENST00000524851	866	243aa	ENSP00000433821
RPS3-206	ENST00000526248	771	135aa	ENSP00000431737
RPS3-213	ENST00000529285	550	No protein	-
RPS3-220	ENST00000534555	387	No protein	-
RPS3-211	ENST00000528847	639	36aa	ENSP00000435566
RPS3-205	ENST00000525933	1307	171aa	ENSP00000436556
RPS3-204	ENST00000525690	421	33aa	ENSP00000436476
RPS3-215	ENST00000530170	531	123aa	ENSP00000437105

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000149273	homo_sapiens	ENSP00000496813	38.5057	24.1379	homo_sapiens	ENSP00000434643	27.572	17.284

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	pan_paniscus	ENSPPAP00000012063	100	100
ENSG00000149273	homo_sapiens	ENSP00000434643	97.9424	97.1193	pongo_abelii	ENSPPYP00000004215	90.8397	90.0763
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	pan_troglodytes	ENSPTRP00000062955	100	100
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	gorilla_gorilla	ENSGGOP00000006379	100	100
ENSG00000149273	homo_sapiens	ENSP00000434643	98.7654	98.3539	notamacropus_eugenii	ENSMEUP00000010558	98.7654	98.3539
ENSG00000149273	homo_sapiens	ENSP00000434643	83.9506	81.07	choloepus_hoffmanni	ENSCHOP00000004720	93.1507	89.9543
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	dasypus_novemcinctus	ENSDNOP00000011538	91.3534	90.9774
ENSG00000149273	homo_sapiens	ENSP00000434643	98.3539	97.5309	erinaceus_europaeus	ENSEEUP00000013268	98.3539	97.5309
ENSG00000149273	homo_sapiens	ENSP00000434643	82.716	82.716	echinops_telfairi	ENSETEP00000012566	82.716	82.716
ENSG00000149273	homo_sapiens	ENSP00000434643	99.5885	99.5885	callithrix_jacchus	ENSCJAP00000028461	85.8156	85.8156
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	cercocebus_atys	ENSCATP00000023620	90.6716	90.6716
ENSG00000149273	homo_sapiens	ENSP00000434643	29.6296	29.6296	macaca_fascicularis	ENSMFAP00000039612	93.5065	93.5065
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	macaca_mulatta	ENSMMUP00000036826	100	100
ENSG00000149273	homo_sapiens	ENSP00000434643	63.786	62.5514	macaca_nemestrina	ENSMNEP00000040701	94.5122	92.6829
ENSG00000149273	homo_sapiens	ENSP00000434643	78.6008	76.5432	macaca_nemestrina	ENSMNEP00000013168	84.8889	82.6667
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	papio_anubis	ENSPANP00000000733	93.8224	93.8224
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	mandrillus_leucophaeus	ENSMLEP00000006717	93.8224	93.8224
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	tursiops_truncatus	ENSTTRP00000005538	100	100
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	vulpes_vulpes	ENSVVUP00000033702	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	mus_spretus	MGP_SPRETEiJ_P0084207	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	equus_asinus	ENSEASP00005020725	86.4769	86.121
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	capra_hircus	ENSCHIP00000009520	100	100
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	loxodonta_africana	ENSLAFP00000003582	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	panthera_leo	ENSPLOP00000008668	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	bos_indicus_hybrid	ENSBIXP00005045434	86.4769	86.4769
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	oryctolagus_cuniculus	ENSOCUP00000018598	86.4769	86.121
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	equus_caballus	ENSECAP00000011789	86.4769	86.121
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	canis_lupus_familiaris	ENSCAFP00845016559	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	panthera_pardus	ENSPPRP00000028833	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	marmota_marmota_marmota	ENSMMMP00000011026	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	balaenoptera_musculus	ENSBMSP00010009113	100	100
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	cavia_porcellus	ENSCPOP00000028766	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	felis_catus	ENSFCAP00000011080	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	ursus_americanus	ENSUAMP00000027871	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	99.5885	99.177	monodelphis_domestica	ENSMODP00000008611	99.5885	99.177
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	bison_bison_bison	ENSBBBP00000026767	94.186	94.186
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	monodon_monoceros	ENSMMNP00015027057	100	100
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	sus_scrofa	ENSSSCP00000015774	92.7481	92.7481
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	microcebus_murinus	ENSMICP00000020936	100	100
ENSG00000149273	homo_sapiens	ENSP00000434643	89.3004	88.0658	octodon_degus	ENSODEP00000003298	95.5947	94.2731
ENSG00000149273	homo_sapiens	ENSP00000434643	57.2016	53.4979	octodon_degus	ENSODEP00000002300	90.2597	84.4156
ENSG00000149273	homo_sapiens	ENSP00000434643	89.3004	87.6543	octodon_degus	ENSODEP00000000781	95.1754	93.4211
ENSG00000149273	homo_sapiens	ENSP00000434643	80.6584	75.3086	octodon_degus	ENSODEP00000001653	87.8924	82.0628
ENSG00000149273	homo_sapiens	ENSP00000434643	44.0329	41.5638	octodon_degus	ENSODEP00000004932	89.1667	84.1667
ENSG00000149273	homo_sapiens	ENSP00000434643	65.8436	64.6091	octodon_degus	ENSODEP00000009109	99.3789	97.5155
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	jaculus_jaculus	ENSJJAP00000017418	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	ovis_aries_rambouillet	ENSOARP00020006090	93.4615	93.4615
ENSG00000149273	homo_sapiens	ENSP00000434643	73.251	72.8395	ochotona_princeps	ENSOPRP00000008678	73.251	72.8395
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	delphinapterus_leucas	ENSDLEP00000003876	100	100
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	physeter_catodon	ENSPCTP00005017935	100	100
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	mus_caroli	MGP_CAROLIEiJ_P0080837	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	mus_musculus	ENSMUSP00000032998	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	dipodomys_ordii	ENSDORP00000002794	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	mustela_putorius_furo	ENSMPUP00000009120	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	aotus_nancymaae	ENSANAP00000019862	93.8224	93.8224
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	saimiri_boliviensis_boliviensis	ENSSBOP00000010077	93.8224	93.8224
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	vicugna_pacos	ENSVPAP00000010808	100	100
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	chlorocebus_sabaeus	ENSCSAP00000000282	100	100
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	tupaia_belangeri	ENSTBEP00000006091	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	94.2387	93.0041	mesocricetus_auratus	ENSMAUP00000004722	98.7069	97.4138
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	phocoena_sinus	ENSPSNP00000008404	100	100
ENSG00000149273	homo_sapiens	ENSP00000434643	94.2387	92.5926	carlito_syrichta	ENSTSYP00000018615	84.8148	83.3333
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	panthera_tigris_altaica	ENSPTIP00000012853	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	97.5309	95.8848	rattus_norvegicus	ENSRNOP00000009988	97.5309	95.8848
ENSG00000149273	homo_sapiens	ENSP00000434643	61.7284	61.7284	prolemur_simus	ENSPSMP00000026649	99.3377	99.3377
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	prolemur_simus	ENSPSMP00000003736	100	100
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	microtus_ochrogaster	ENSMOCP00000007818	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	95.0617	94.6502	sorex_araneus	ENSSARP00000006343	95.8506	95.4357
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	peromyscus_maniculatus_bairdii	ENSPEMP00000025262	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	bos_mutus	ENSBMUP00000004815	94.186	94.186
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	mus_spicilegus	ENSMSIP00000032663	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	76.9547	73.6626	cricetulus_griseus_chok1gshd	ENSCGRP00001003156	90.7767	86.8932
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	cricetulus_griseus_chok1gshd	ENSCGRP00001012207	86.4769	86.121
ENSG00000149273	homo_sapiens	ENSP00000434643	94.2387	93.8272	pteropus_vampyrus	ENSPVAP00000010626	94.6281	94.2149
ENSG00000149273	homo_sapiens	ENSP00000434643	99.5885	99.177	myotis_lucifugus	ENSMLUP00000003714	99.5885	99.177
ENSG00000149273	homo_sapiens	ENSP00000434643	60.0823	56.7901	vombatus_ursinus	ENSVURP00010007928	90.6832	85.7143
ENSG00000149273	homo_sapiens	ENSP00000434643	59.2593	57.2016	vombatus_ursinus	ENSVURP00010003617	96.6443	93.2886
ENSG00000149273	homo_sapiens	ENSP00000434643	98.7654	98.3539	vombatus_ursinus	ENSVURP00010022232	98.7654	98.3539
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	rhinolophus_ferrumequinum	ENSRFEP00010027399	86.4769	86.121
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	neovison_vison	ENSNVIP00000029223	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	bos_taurus	ENSBTAP00000003962	100	100
ENSG00000149273	homo_sapiens	ENSP00000434643	99.5885	99.177	heterocephalus_glaber_female	ENSHGLP00000027191	99.5885	99.177
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	rhinopithecus_bieti	ENSRBIP00000043513	100	100
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	canis_lupus_dingo	ENSCAFP00020002483	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	66.2551	65.8436	sciurus_vulgaris	ENSSVLP00005020573	100	99.3789
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	sciurus_vulgaris	ENSSVLP00005028030	94.186	93.7984
ENSG00000149273	homo_sapiens	ENSP00000434643	56.3786	53.0864	phascolarctos_cinereus	ENSPCIP00000025254	80.5882	75.8824
ENSG00000149273	homo_sapiens	ENSP00000434643	98.7654	98.3539	phascolarctos_cinereus	ENSPCIP00000032530	98.7654	98.3539
ENSG00000149273	homo_sapiens	ENSP00000434643	30.8642	28.8066	phascolarctos_cinereus	ENSPCIP00000051280	89.2857	83.3333
ENSG00000149273	homo_sapiens	ENSP00000434643	60.0823	57.2016	phascolarctos_cinereus	ENSPCIP00000030287	96.6887	92.053
ENSG00000149273	homo_sapiens	ENSP00000434643	81.893	81.07	procavia_capensis	ENSPCAP00000002830	81.893	81.07
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	nannospalax_galili	ENSNGAP00000014114	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	bos_grunniens	ENSBGRP00000037211	86.4769	86.4769
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	chinchilla_lanigera	ENSCLAP00000020172	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	cervus_hanglu_yarkandensis	ENSCHYP00000007057	62.6289	62.6289
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	catagonus_wagneri	ENSCWAP00000002419	92.7481	92.7481
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	otolemur_garnettii	ENSOGAP00000004758	99.5902	99.5902
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	cebus_imitator	ENSCCAP00000008838	90	90
ENSG00000149273	homo_sapiens	ENSP00000434643	99.5885	99.177	urocitellus_parryii	ENSUPAP00010016925	99.5885	99.177
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	moschus_moschiferus	ENSMMSP00000013766	94.186	94.186
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	rhinopithecus_roxellana	ENSRROP00000002484	100	100
ENSG00000149273	homo_sapiens	ENSP00000434643	100	99.5885	mus_pahari	MGP_PahariEiJ_P0017676	100	99.5885
ENSG00000149273	homo_sapiens	ENSP00000434643	100	100	propithecus_coquereli	ENSPCOP00000031940	100	100
ENSG00000149273	homo_sapiens	ENSP00000434643	85.1852	74.4856	caenorhabditis_elegans	C23G10.3.1	83.8057	73.2794
ENSG00000149273	homo_sapiens	ENSP00000434643	87.6543	80.2469	drosophila_melanogaster	FBpp0312066	86.5854	79.2683
ENSG00000149273	homo_sapiens	ENSP00000434643	88.4774	85.5967	ciona_intestinalis	ENSCINP00000010313	81.749	79.0875
ENSG00000149273	homo_sapiens	ENSP00000434643	78.6008	74.0741	petromyzon_marinus	ENSPMAP00000008596	95.5	90
ENSG00000149273	homo_sapiens	ENSP00000434643	59.2593	53.0864	eptatretus_burgeri	ENSEBUP00000005415	79.558	71.2707
ENSG00000149273	homo_sapiens	ENSP00000434643	98.3539	97.5309	callorhinchus_milii	ENSCMIP00000043843	95.6	94.8
ENSG00000149273	homo_sapiens	ENSP00000434643	98.3539	95.4733	fundulus_heteroclitus	ENSFHEP00000034432	97.551	94.6939
ENSG00000149273	homo_sapiens	ENSP00000434643	98.3539	97.5309	notechis_scutatus	ENSNSUP00000023821	98.3539	97.5309
ENSG00000149273	homo_sapiens	ENSP00000434643	98.3539	97.5309	pseudonaja_textilis	ENSPTXP00000021463	98.3539	97.5309
ENSG00000149273	homo_sapiens	ENSP00000434643	86.8313	84.3621	naja_naja	ENSNNAP00000012024	84.4	82
ENSG00000149273	homo_sapiens	ENSP00000434643	88.4774	84.7737	ciona_savignyi	ENSCSAVP00000005843	83.6576	80.1556
ENSG00000149273	homo_sapiens	ENSP00000434643	77.7778	65.8436	saccharomyces_cerevisiae	YNL178W	78.75	66.6667
ENSG00000149273	homo_sapiens	ENSP00000434643	97.9424	97.1193	nothobranchius_furzeri	ENSNFUP00015032038	94.4444	93.6508

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000977	contributes_to RNA polymerase II transcription regulatory region sequence-specific DNA binding	1	IMP	Homo_sapiens(9606)	Function
GO:0002181	involved_in cytoplasmic translation	2	IC,NAS	Homo_sapiens(9606)	Process
GO:0003677	enables DNA binding	1	IDA	Homo_sapiens(9606)	Function
GO:0003684	enables damaged DNA binding	1	IDA	Homo_sapiens(9606)	Function
GO:0003723	enables RNA binding	2	HDA,IDA	Homo_sapiens(9606)	Function
GO:0003729	enables mRNA binding	1	IDA	Homo_sapiens(9606)	Function
GO:0003735	enables structural constituent of ribosome	4	HDA,IBA,IDA,NAS	Homo_sapiens(9606)	Function
GO:0003906	enables DNA-(apurinic or apyrimidinic site) endonuclease activity	1	IDA	Homo_sapiens(9606)	Function
GO:0004520	enables DNA endonuclease activity	1	IDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	3	IBA,IDA,IMP	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	TAS	Homo_sapiens(9606)	Component
GO:0005730	located_in nucleolus	1	IDA	Homo_sapiens(9606)	Component
GO:0005737	located_in cytoplasm	3	IDA,IMP,NAS	Homo_sapiens(9606)	Component
GO:0005743	located_in mitochondrial inner membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0005759	located_in mitochondrial matrix	1	IDA	Homo_sapiens(9606)	Component
GO:0005783	located_in endoplasmic reticulum	1	IDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0005840	located_in ribosome	1	IDA	Homo_sapiens(9606)	Component
GO:0005844	part_of polysome	1	IDA	Homo_sapiens(9606)	Component
GO:0005886	located_in plasma membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0005925	located_in focal adhesion	1	HDA	Homo_sapiens(9606)	Component
GO:0006281	involved_in DNA repair	1	IMP	Homo_sapiens(9606)	Process
GO:0006284	involved_in base-excision repair	1	IDA	Homo_sapiens(9606)	Process
GO:0006412	involved_in translation	2	IC,NAS	Homo_sapiens(9606)	Process
GO:0006413	involved_in translational initiation	1	NAS	Homo_sapiens(9606)	Process
GO:0006915	involved_in apoptotic process	1	IEA	Homo_sapiens(9606)	Process
GO:0006974	involved_in DNA damage response	1	IEP	Homo_sapiens(9606)	Process
GO:0007059	involved_in chromosome segregation	1	IMP	Homo_sapiens(9606)	Process
GO:0008017	enables microtubule binding	1	IDA	Homo_sapiens(9606)	Function
GO:0010628	involved_in positive regulation of gene expression	1	IMP	Homo_sapiens(9606)	Process
GO:0014069	is_active_in postsynaptic density	2	EXP,IDA	Homo_sapiens(9606)	Component
GO:0015631	enables tubulin binding	1	IDA	Homo_sapiens(9606)	Function
GO:0016020	located_in membrane	1	HDA	Homo_sapiens(9606)	Component
GO:0017148	involved_in negative regulation of translation	1	IDA	Homo_sapiens(9606)	Process
GO:0019104	NOT enables DNA N-glycosylase activity	2	IDA,TAS	Homo_sapiens(9606)	Function
GO:0019899	enables enzyme binding	1	IPI	Homo_sapiens(9606)	Function
GO:0019900	enables kinase binding	1	IPI	Homo_sapiens(9606)	Function
GO:0019901	enables protein kinase binding	1	IPI	Homo_sapiens(9606)	Function
GO:0022626	located_in cytosolic ribosome	1	IDA	Homo_sapiens(9606)	Component
GO:0022627	part_of cytosolic small ribosomal subunit	4	HDA,IBA,IDA,NAS	Homo_sapiens(9606)	Component
GO:0030544	enables Hsp70 protein binding	1	IDA	Homo_sapiens(9606)	Function
GO:0031116	involved_in positive regulation of microtubule polymerization	1	IMP	Homo_sapiens(9606)	Process
GO:0031334	involved_in positive regulation of protein-containing complex assembly	1	IMP	Homo_sapiens(9606)	Process
GO:0031397	involved_in negative regulation of protein ubiquitination	1	IDA	Homo_sapiens(9606)	Process
GO:0032079	involved_in positive regulation of endodeoxyribonuclease activity	1	IDA	Homo_sapiens(9606)	Process
GO:0032357	enables oxidized purine DNA binding	1	IDA	Homo_sapiens(9606)	Function
GO:0032358	enables oxidized pyrimidine DNA binding	1	IDA	Homo_sapiens(9606)	Function
GO:0032587	located_in ruffle membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0032743	involved_in positive regulation of interleukin-2 production	1	IMP	Homo_sapiens(9606)	Process
GO:0034614	involved_in cellular response to reactive oxygen species	1	IDA	Homo_sapiens(9606)	Process
GO:0042104	involved_in positive regulation of activated T cell proliferation	1	IMP	Homo_sapiens(9606)	Process
GO:0042981	involved_in regulation of apoptotic process	1	IMP	Homo_sapiens(9606)	Process
GO:0043507	involved_in positive regulation of JUN kinase activity	1	IMP	Homo_sapiens(9606)	Process
GO:0044390	enables ubiquitin-like protein conjugating enzyme binding	1	IPI	Homo_sapiens(9606)	Function
GO:0044877	enables protein-containing complex binding	1	IMP	Homo_sapiens(9606)	Function
GO:0045738	involved_in negative regulation of DNA repair	1	IMP	Homo_sapiens(9606)	Process
GO:0045739	involved_in positive regulation of DNA repair	1	IDA	Homo_sapiens(9606)	Process
GO:0050862	involved_in positive regulation of T cell receptor signaling pathway	1	IMP	Homo_sapiens(9606)	Process
GO:0051018	enables protein kinase A binding	1	IPI	Homo_sapiens(9606)	Function
GO:0051092	involved_in positive regulation of NF-kappaB transcription factor activity	2	IGI,IMP	Homo_sapiens(9606)	Process
GO:0051225	involved_in spindle assembly	1	IMP	Homo_sapiens(9606)	Process
GO:0051301	involved_in cell division	1	IEA	Homo_sapiens(9606)	Process
GO:0051536	enables iron-sulfur cluster binding	1	NAS	Homo_sapiens(9606)	Function
GO:0051879	enables Hsp90 protein binding	1	IDA	Homo_sapiens(9606)	Function
GO:0061481	involved_in response to TNF agonist	1	IDA	Homo_sapiens(9606)	Process
GO:0070062	located_in extracellular exosome	1	HDA	Homo_sapiens(9606)	Component
GO:0070181	enables small ribosomal subunit rRNA binding	1	IDA	Homo_sapiens(9606)	Function
GO:0070301	involved_in cellular response to hydrogen peroxide	1	IDA	Homo_sapiens(9606)	Process
GO:0071159	part_of NF-kappaB complex	1	IDA	Homo_sapiens(9606)	Component
GO:0071356	involved_in cellular response to tumor necrosis factor	1	IMP	Homo_sapiens(9606)	Process
GO:0072686	located_in mitotic spindle	1	IDA	Homo_sapiens(9606)	Component
GO:0097100	enables supercoiled DNA binding	1	IDA	Homo_sapiens(9606)	Function
GO:0140078	enables class I DNA-(apurinic or apyrimidinic site) endonuclease activity	1	IEA	Homo_sapiens(9606)	Function
GO:0140297	enables DNA-binding transcription factor binding	1	IPI	Homo_sapiens(9606)	Function
GO:1901224	involved_in positive regulation of NIK/NF-kappaB signaling	1	IDA	Homo_sapiens(9606)	Process
GO:1902231	involved_in positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage	1	IMP	Homo_sapiens(9606)	Process
GO:1905053	involved_in positive regulation of base-excision repair	1	IDA	Homo_sapiens(9606)	Process
GO:1990904	part_of ribonucleoprotein complex	1	IDA	Homo_sapiens(9606)	Component
GO:2001235	involved_in positive regulation of apoptotic signaling pathway	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:2001272	involved_in positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	1	IMP	Homo_sapiens(9606)	Process