Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerSARS-COV-2
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq DataSet_01_274 DataSet_01_352

Description

Ensembl ID ENSG00000144381 Gene ID 3329 Accession 5261
Symbol HSPD1 Alias HLD4;CPN60;GROEL;HSP60;HSP65;SPG13;HSP-60;HuCHA60 Full Name heat shock protein family D (Hsp60) member 1
Status Confidence Length 30154 bases Strand Minus strand
Position 2 : 197486584 - 197516737 RNA binding domain N.A.
Summary This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq, Jun 2010]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
HSPD1-202 ENST00000388968 2245 573aa ENSP00000373620
HSPD1-216 ENST00000677454 2320 322aa ENSP00000503295
HSPD1-218 ENST00000677913 2257 573aa ENSP00000503139
HSPD1-222 ENST00000678761 2252 573aa ENSP00000503894
HSPD1-217 ENST00000677792 2195 296aa ENSP00000504645
HSPD1-210 ENST00000461097 4930 No protein -
HSPD1-208 ENST00000440114 2178 48aa ENSP00000390404
HSPD1-207 ENST00000439605 2510 573aa ENSP00000402478
HSPD1-203 ENST00000418022 2540 573aa ENSP00000412227
HSPD1-205 ENST00000428204 2449 573aa ENSP00000396460
HSPD1-223 ENST00000678969 3772 No protein -
HSPD1-211 ENST00000476746 3230 No protein -
HSPD1-219 ENST00000678170 2022 482aa ENSP00000503910
HSPD1-214 ENST00000676933 2200 541aa ENSP00000503144
HSPD1-221 ENST00000678621 2413 537aa ENSP00000504328
HSPD1-220 ENST00000678545 2564 310aa ENSP00000502920
HSPD1-215 ENST00000677403 2468 375aa ENSP00000504667
HSPD1-224 ENST00000679291 2210 296aa ENSP00000504417
HSPD1-209 ENST00000452200 2407 573aa ENSP00000412717
HSPD1-201 ENST00000345042 2299 573aa ENSP00000340019
HSPD1-204 ENST00000426480 2312 573aa ENSP00000414446
HSPD1-213 ENST00000491249 860 No protein -
HSPD1-212 ENST00000486181 648 No protein -
HSPD1-206 ENST00000430176 745 231aa ENSP00000393670

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000144381homo_sapiensENSP0000027560339.359722.0339homo_sapiensENSP0000037362036.474720.4188
ENSG00000144381homo_sapiensENSP0000025809139.77921.1786homo_sapiensENSP0000037362037.696320.0698
ENSG00000144381homo_sapiensENSP0000024606228.771913.5088homo_sapiensENSP0000037362028.621313.438
ENSG00000144381homo_sapiensENSP0000035304829.98214.9013homo_sapiensENSP0000037362029.144914.4852
ENSG00000144381homo_sapiensENSP0000031906223.09869.85915homo_sapiensENSP0000037362028.621312.2164
ENSG00000144381homo_sapiensENSP0000026438011.15355.67207homo_sapiensENSP0000037362040.837720.7679
ENSG00000144381homo_sapiensENSP0000032719139.811322.0755homo_sapiensENSP0000037362036.823720.4188
ENSG00000144381homo_sapiensENSP0000028678836.678818.0657homo_sapiensENSP0000037362035.078517.2775
ENSG00000144381homo_sapiensENSP0000029930036.448618.1308homo_sapiensENSP0000037362034.031416.9284
ENSG00000144381homo_sapiensENSP0000037795837.847917.2542homo_sapiensENSP0000037362035.602116.2304
ENSG00000144381homo_sapiensENSP0000029568838.532118.5321homo_sapiensENSP0000037362036.649217.6265
ENSG00000144381homo_sapiensENSP0000028032639.371518.6691homo_sapiensENSP0000037362037.172817.6265
ENSG00000144381homo_sapiensENSP0000031733437.949619.2446homo_sapiensENSP0000037362036.823718.6736

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000144381homo_sapiensENSP0000037362010099.8255pan_paniscusENSPPAP0000003194995.819495.6522
ENSG00000144381homo_sapiensENSP0000037362010099.8255pan_troglodytesENSPTRP0000006158995.819495.6522
ENSG00000144381homo_sapiensENSP0000037362010099.651gorilla_gorillaENSGGOP0000000808194.088793.7603
ENSG00000144381homo_sapiensENSP0000037362096.684192.8447ornithorhynchus_anatinusENSOANP0000001651497.19393.3333
ENSG00000144381homo_sapiensENSP0000037362098.778494.9389sarcophilus_harrisiiENSSHAP0000002093292.483788.8889
ENSG00000144381homo_sapiensENSP0000037362064.397961.6056notamacropus_eugeniiENSMEUP0000001091984.827681.1494
ENSG00000144381homo_sapiensENSP0000037362078.18577.836choloepus_hoffmanniENSCHOP0000000655486.486586.1004
ENSG00000144381homo_sapiensENSP0000037362063.176361.9546erinaceus_europaeusENSEEUP0000000641783.218481.6092
ENSG00000144381homo_sapiensENSP0000037362084.816883.7696echinops_telfairiENSETEP0000000745994.368993.2039
ENSG00000144381homo_sapiensENSP0000037362010099.651callithrix_jacchusENSCJAP0000004676510099.651
ENSG00000144381homo_sapiensENSP0000037362090.575989.8778cercocebus_atysENSCATP0000004323099.235298.4704
ENSG00000144381homo_sapiensENSP0000037362093.542892.4956macaca_fascicularisENSMFAP0000000093499.075897.9667
ENSG00000144381homo_sapiensENSP0000037362099.825599.1274macaca_fascicularisENSMFAP0000002004599.825599.1274
ENSG00000144381homo_sapiensENSP0000037362099.301997.9058macaca_mulattaENSMMUP0000000946298.613597.227
ENSG00000144381homo_sapiensENSP0000037362099.825599.1274macaca_mulattaENSMMUP0000001712999.825599.1274
ENSG00000144381homo_sapiensENSP0000037362096.335195.4625papio_anubisENSPANP0000000486599.819298.915
ENSG00000144381homo_sapiensENSP0000037362099.825598.6038papio_anubisENSPANP0000003330099.825598.6038
ENSG00000144381homo_sapiensENSP0000037362098.778498.0803mandrillus_leucophaeusENSMLEP0000001916299.823699.1182
ENSG00000144381homo_sapiensENSP0000037362099.127497.5567tursiops_truncatusENSTTRP0000000320599.127497.5567
ENSG00000144381homo_sapiensENSP0000037362098.952998.0803vulpes_vulpesENSVVUP0000003610998.952998.0803
ENSG00000144381homo_sapiensENSP0000037362034.90434.7295mus_spretusMGP_SPRETEiJ_P001867899.009998.5149
ENSG00000144381homo_sapiensENSP0000037362098.778497.5567equus_asinusENSEASP0000502962798.778497.5567
ENSG00000144381homo_sapiensENSP0000037362089.005286.7365equus_asinusENSEASP0000505817594.444492.037
ENSG00000144381homo_sapiensENSP0000037362098.778498.0803capra_hircusENSCHIP0000000202098.778498.0803
ENSG00000144381homo_sapiensENSP0000037362098.778497.7312loxodonta_africanaENSLAFP0000000004598.778497.7312
ENSG00000144381homo_sapiensENSP0000037362098.952998.2548panthera_leoENSPLOP0000001672098.952998.2548
ENSG00000144381homo_sapiensENSP0000037362098.952998.2548ailuropoda_melanoleucaENSAMEP0000001453398.952998.2548
ENSG00000144381homo_sapiensENSP0000037362098.254897.2077bos_indicus_hybridENSBIXP0000504165498.254897.2077
ENSG00000144381homo_sapiensENSP0000037362098.778497.9058bos_indicus_hybridENSBIXP0000502942498.778497.9058
ENSG00000144381homo_sapiensENSP0000037362099.301998.6038oryctolagus_cuniculusENSOCUP0000001095899.301998.6038
ENSG00000144381homo_sapiensENSP0000037362098.778497.5567equus_caballusENSECAP0000007249196.422595.23
ENSG00000144381homo_sapiensENSP0000037362022.862122.5131canis_lupus_familiarisENSCAFP0084500388995.620494.1606
ENSG00000144381homo_sapiensENSP0000037362099.127498.2548panthera_pardusENSPPRP0000001576499.127498.2548
ENSG00000144381homo_sapiensENSP0000037362098.952998.0803panthera_pardusENSPPRP0000001391894.18693.3555
ENSG00000144381homo_sapiensENSP0000037362097.556796.6841marmota_marmota_marmotaENSMMMP0000000502597.556796.6841
ENSG00000144381homo_sapiensENSP0000037362098.429397.7312marmota_marmota_marmotaENSMMMP0000001246798.429397.7312
ENSG00000144381homo_sapiensENSP0000037362099.127497.7312balaenoptera_musculusENSBMSP0001000366599.127497.7312
ENSG00000144381homo_sapiensENSP0000037362097.382295.986cavia_porcellusENSCPOP0000001698797.212595.8188
ENSG00000144381homo_sapiensENSP0000037362099.127498.4293felis_catusENSFCAP0000001923499.127498.4293
ENSG00000144381homo_sapiensENSP0000037362076.614369.808monodelphis_domesticaENSMODP0000004282986.930779.2079
ENSG00000144381homo_sapiensENSP0000037362098.778497.9058bison_bison_bisonENSBBBP0000001999098.778497.9058
ENSG00000144381homo_sapiensENSP0000037362061.605659.6859monodon_monocerosENSMMNP0001501707992.894790
ENSG00000144381homo_sapiensENSP0000037362082.89781.6754sus_scrofaENSSSCP0000007965598.547797.0954
ENSG00000144381homo_sapiensENSP0000037362099.476498.9529microcebus_murinusENSMICP0000003892593.904493.4102
ENSG00000144381homo_sapiensENSP0000037362091.797688.1326octodon_degusENSODEP0000000364994.434590.6643
ENSG00000144381homo_sapiensENSP0000037362083.769678.7085octodon_degusENSODEP0000000519189.887684.4569
ENSG00000144381homo_sapiensENSP0000037362034.380534.2059octodon_degusENSODEP0000001216397.524797.0297
ENSG00000144381homo_sapiensENSP0000037362091.27487.7836octodon_degusENSODEP0000002355592.895289.3428
ENSG00000144381homo_sapiensENSP0000037362093.019289.3543octodon_degusENSODEP0000002611993.019289.3543
ENSG00000144381homo_sapiensENSP0000037362029.319428.7958jaculus_jaculusENSJJAP0000001417798.823597.0588
ENSG00000144381homo_sapiensENSP0000037362094.240892.3211ovis_aries_rambouilletENSOARP0002003416194.405692.4825
ENSG00000144381homo_sapiensENSP0000037362099.127498.2548ursus_maritimusENSUMAP0000002886399.127498.2548
ENSG00000144381homo_sapiensENSP0000037362071.727770.8551ochotona_princepsENSOPRP0000000140883.367182.3529
ENSG00000144381homo_sapiensENSP0000037362090.92589.1798delphinapterus_leucasENSDLEP0000002338596.840194.9814
ENSG00000144381homo_sapiensENSP0000037362098.778497.5567physeter_catodonENSPCTP0000500082596.095194.9066
ENSG00000144381homo_sapiensENSP0000037362098.254897.5567mus_caroliMGP_CAROLIEiJ_P001767398.254897.5567
ENSG00000144381homo_sapiensENSP0000037362098.254897.5567mus_musculusENSMUSP0000002712398.254897.5567
ENSG00000144381homo_sapiensENSP0000037362099.127498.0803dipodomys_ordiiENSDORP0000001040299.127498.0803
ENSG00000144381homo_sapiensENSP0000037362099.825599.3019aotus_nancymaaeENSANAP0000000036793.924593.4319
ENSG00000144381homo_sapiensENSP0000037362099.825599.651saimiri_boliviensis_boliviensisENSSBOP0000003570993.770593.6066
ENSG00000144381homo_sapiensENSP0000037362093.019292.1466vicugna_pacosENSVPAP0000000538793.019292.1466
ENSG00000144381homo_sapiensENSP0000037362098.952997.9058chlorocebus_sabaeusENSCSAP0000000763295.134294.1275
ENSG00000144381homo_sapiensENSP0000037362060.383960.0349tupaia_belangeriENSTBEP0000000221960.383960.0349
ENSG00000144381homo_sapiensENSP0000037362098.952997.5567phocoena_sinusENSPSNP0000002789696.264994.9066
ENSG00000144381homo_sapiensENSP0000037362098.952998.0803camelus_dromedariusENSCDRP0000501709998.952998.0803
ENSG00000144381homo_sapiensENSP0000037362083.944280.8028carlito_syrichtaENSTSYP0000003279386.666783.4234
ENSG00000144381homo_sapiensENSP0000037362094.415492.3211carlito_syrichtaENSTSYP0000001505591.385189.3581
ENSG00000144381homo_sapiensENSP0000037362098.952998.0803carlito_syrichtaENSTSYP0000000047594.974994.1374
ENSG00000144381homo_sapiensENSP0000037362099.127498.4293panthera_tigris_altaicaENSPTIP0000000418699.127498.4293
ENSG00000144381homo_sapiensENSP0000037362097.033295.8115rattus_norvegicusENSRNOP0000008999197.033295.8115
ENSG00000144381homo_sapiensENSP0000037362098.254897.5567rattus_norvegicusENSRNOP0000006366698.254897.5567
ENSG00000144381homo_sapiensENSP0000037362099.476499.3019prolemur_simusENSPSMP0000003650097.938197.7663
ENSG00000144381homo_sapiensENSP0000037362093.542892.4956prolemur_simusENSPSMP0000001957093.542892.4956
ENSG00000144381homo_sapiensENSP0000037362090.226988.3072microtus_ochrogasterENSMOCP0000000499798.28996.1977
ENSG00000144381homo_sapiensENSP0000037362092.495690.0524microtus_ochrogasterENSMOCP0000001061196.363693.8182
ENSG00000144381homo_sapiensENSP0000037362034.90434.7295microtus_ochrogasterENSMOCP0000000348699.009998.5149
ENSG00000144381homo_sapiensENSP0000037362097.207795.637sorex_araneusENSSARP0000000641695.704594.1581
ENSG00000144381homo_sapiensENSP0000037362097.905897.0332peromyscus_maniculatus_bairdiiENSPEMP0000001608797.905897.0332
ENSG00000144381homo_sapiensENSP0000037362098.778497.9058bos_mutusENSBMUP0000001307898.778497.9058
ENSG00000144381homo_sapiensENSP0000037362098.254897.5567mus_spicilegusENSMSIP0000002199998.254897.5567
ENSG00000144381homo_sapiensENSP0000037362073.472968.9354cricetulus_griseus_chok1gshdENSCGRP0000102429789.574584.0426
ENSG00000144381homo_sapiensENSP0000037362098.254897.5567pteropus_vampyrusENSPVAP0000000784498.083697.3868
ENSG00000144381homo_sapiensENSP0000037362040.314135.0785myotis_lucifugusENSMLUP0000001670086.516975.2809
ENSG00000144381homo_sapiensENSP0000037362098.254894.5899vombatus_ursinusENSVURP0001002214298.254894.5899
ENSG00000144381homo_sapiensENSP0000037362098.429396.8586rhinolophus_ferrumequinumENSRFEP0001003358098.429396.8586
ENSG00000144381homo_sapiensENSP0000037362098.254897.2077bos_taurusENSBTAP0000005907798.254897.2077
ENSG00000144381homo_sapiensENSP0000037362098.778497.9058bos_taurusENSBTAP0000001670898.778497.9058
ENSG00000144381homo_sapiensENSP0000037362098.254897.0332heterocephalus_glaber_femaleENSHGLP0000004856398.254897.0332
ENSG00000144381homo_sapiensENSP0000037362098.778497.9058rhinopithecus_bietiENSRBIP0000003404895.446994.6037
ENSG00000144381homo_sapiensENSP0000037362098.778497.9058rhinopithecus_bietiENSRBIP0000003889893.86493.0348
ENSG00000144381homo_sapiensENSP0000037362086.91185.1658rhinopithecus_bietiENSRBIP0000001562395.402393.4866
ENSG00000144381homo_sapiensENSP0000037362098.952998.0803canis_lupus_dingoENSCAFP0002000580098.952998.0803
ENSG00000144381homo_sapiensENSP0000037362098.254897.5567sciurus_vulgarisENSSVLP0000502179598.254897.5567
ENSG00000144381homo_sapiensENSP0000037362098.952998.2548sciurus_vulgarisENSSVLP0000500363398.952998.2548
ENSG00000144381homo_sapiensENSP0000037362098.080394.4154phascolarctos_cinereusENSPCIP0000001350888.643585.3312
ENSG00000144381homo_sapiensENSP0000037362097.382296.6841procavia_capensisENSPCAP0000000882797.552496.8531
ENSG00000144381homo_sapiensENSP0000037362078.18574.171nannospalax_galiliENSNGAP0000001650287.843183.3333
ENSG00000144381homo_sapiensENSP0000037362098.778497.9058bos_grunniensENSBGRP0000000082398.778497.9058
ENSG00000144381homo_sapiensENSP0000037362098.778497.7312chinchilla_lanigeraENSCLAP0000001682498.778497.7312
ENSG00000144381homo_sapiensENSP0000037362098.778497.7312cervus_hanglu_yarkandensisENSCHYP0000002030198.778497.7312
ENSG00000144381homo_sapiensENSP0000037362089.877888.3072cervus_hanglu_yarkandensisENSCHYP0000002933195.547393.8775
ENSG00000144381homo_sapiensENSP0000037362098.603897.0332catagonus_wagneriENSCWAP0000000991099.122897.5439
ENSG00000144381homo_sapiensENSP0000037362034.90434.7295ictidomys_tridecemlineatusENSSTOP0000002046499.009998.5149
ENSG00000144381homo_sapiensENSP0000037362058.464254.4503otolemur_garnettiiENSOGAP0000001733788.859482.7586
ENSG00000144381homo_sapiensENSP0000037362080.453875.7417otolemur_garnettiiENSOGAP0000001770890.569785.2652
ENSG00000144381homo_sapiensENSP0000037362099.65199.3019cebus_imitatorENSCCAP0000001968995.484995.1505
ENSG00000144381homo_sapiensENSP0000037362087.783687.4346cebus_imitatorENSCCAP0000002209599.801699.4048
ENSG00000144381homo_sapiensENSP0000037362098.778497.9058moschus_moschiferusENSMMSP0000001475298.778497.9058
ENSG00000144381homo_sapiensENSP0000037362043.804543.281rhinopithecus_roxellanaENSRROP0000000151599.209598.0237
ENSG00000144381homo_sapiensENSP0000037362099.825598.9529rhinopithecus_roxellanaENSRROP0000001298194.078993.2566
ENSG00000144381homo_sapiensENSP0000037362099.825598.9529rhinopithecus_roxellanaENSRROP0000001463995.492594.6578
ENSG00000144381homo_sapiensENSP0000037362034.729534.555mus_pahariMGP_PahariEiJ_P007298998.514998.0198
ENSG00000144381homo_sapiensENSP0000037362099.301998.4293propithecus_coquereliENSPCOP0000000589993.278792.459
ENSG00000144381homo_sapiensENSP0000037362082.373571.3787caenorhabditis_elegansY22D7AL.5a.183.098672.007
ENSG00000144381homo_sapiensENSP0000037362075.741758.4642drosophila_melanogasterFBpp007766566.975351.6975
ENSG00000144381homo_sapiensENSP0000037362063.525340.3141drosophila_melanogasterFBpp008009665.23341.3979
ENSG00000144381homo_sapiensENSP0000037362086.56274.171drosophila_melanogasterFBpp007329086.56274.171
ENSG00000144381homo_sapiensENSP0000037362084.118771.9023drosophila_melanogasterFBpp007874283.680671.5278
ENSG00000144381homo_sapiensENSP0000037362083.944271.2042ciona_intestinalisENSCINP0000001602283.797971.0801
ENSG00000144381homo_sapiensENSP0000037362067.539360.2094petromyzon_marinusENSPMAP0000000257494.390284.1463
ENSG00000144381homo_sapiensENSP0000037362082.89770.5061eptatretus_burgeriENSEBUP0000002551889.792176.3705
ENSG00000144381homo_sapiensENSP0000037362094.764486.2129callorhinchus_miliiENSCMIP0000002958693.459585.0258
ENSG00000144381homo_sapiensENSP0000037362094.764490.2269latimeria_chalumnaeENSLACP0000001736796.106291.5044
ENSG00000144381homo_sapiensENSP0000037362094.589988.8307lepisosteus_oculatusENSLOCP0000000470894.589988.8307
ENSG00000144381homo_sapiensENSP0000037362092.670285.6894clupea_harengusENSCHAP0000004984690.769283.9316
ENSG00000144381homo_sapiensENSP0000037362093.542885.3403clupea_harengusENSCHAP0000004333792.254784.1652
ENSG00000144381homo_sapiensENSP0000037362094.938987.7836danio_rerioENSDARP0000007305794.608787.4783
ENSG00000144381homo_sapiensENSP0000037362094.764487.6091carassius_auratusENSCARP0000006112393.782486.7012
ENSG00000144381homo_sapiensENSP0000037362094.415487.26carassius_auratusENSCARP0000010298193.115386.0585
ENSG00000144381homo_sapiensENSP0000037362094.066386.911carassius_auratusENSCARP0000005472393.739186.6087
ENSG00000144381homo_sapiensENSP0000037362094.240887.26astyanax_mexicanusENSAMXP0000000225894.076787.108
ENSG00000144381homo_sapiensENSP0000037362094.066388.3072ictalurus_punctatusENSIPUP0000001934493.739188
ENSG00000144381homo_sapiensENSP0000037362093.542886.0384esox_luciusENSELUP0000002907993.055685.5903
ENSG00000144381homo_sapiensENSP0000037362094.415488.1326electrophorus_electricusENSEEEP0000004066491.385185.3041
ENSG00000144381homo_sapiensENSP0000037362093.717386.911oncorhynchus_kisutchENSOKIP0000500026091.482184.8382
ENSG00000144381homo_sapiensENSP0000037362093.542886.2129oncorhynchus_kisutchENSOKIP0000504910089.482582.4708
ENSG00000144381homo_sapiensENSP0000037362093.542886.2129oncorhynchus_mykissENSOMYP0000004253393.055685.7639
ENSG00000144381homo_sapiensENSP0000037362093.542886.562oncorhynchus_mykissENSOMYP0000003667991.001784.2105
ENSG00000144381homo_sapiensENSP0000037362091.972184.6422salmo_salarENSSSAP0000005572691.334584.0555
ENSG00000144381homo_sapiensENSP0000037362093.368286.0384salmo_salarENSSSAP0000015145388.138481.2191
ENSG00000144381homo_sapiensENSP0000037362093.717386.911salmo_truttaENSSTUP0000002687490.556583.9798
ENSG00000144381homo_sapiensENSP0000037362093.542886.3874salmo_truttaENSSTUP0000002780788.59581.8182
ENSG00000144381homo_sapiensENSP0000037362092.670285.1658gadus_morhuaENSGMOP000000072319082.7119
ENSG00000144381homo_sapiensENSP0000037362093.717386.3874fundulus_heteroclitusENSFHEP0000001262692.906685.6401
ENSG00000144381homo_sapiensENSP0000037362093.717387.4346poecilia_reticulataENSPREP0000002899693.391387.1304
ENSG00000144381homo_sapiensENSP0000037362093.717387.6091xiphophorus_maculatusENSXMAP0000000592093.391387.3043
ENSG00000144381homo_sapiensENSP0000037362093.717386.562oryzias_latipesENSORLP0000002585393.391386.2609
ENSG00000144381homo_sapiensENSP0000037362087.609180.4538cyclopterus_lumpusENSCLMP0000503752689.165281.8828
ENSG00000144381homo_sapiensENSP0000037362093.717387.6091oreochromis_niloticusENSONIP0000001731293.391387.3043
ENSG00000144381homo_sapiensENSP0000037362093.019287.26haplochromis_burtoniENSHBUP0000002564692.695786.9565
ENSG00000144381homo_sapiensENSP0000037362093.019287.26astatotilapia_callipteraENSACLP0000003491892.695786.9565
ENSG00000144381homo_sapiensENSP0000037362093.368286.7365sparus_aurataENSSAUP0001006174892.400785.8377
ENSG00000144381homo_sapiensENSP0000037362094.066388.1326lates_calcariferENSLCAP0001001759492.611786.7698
ENSG00000144381homo_sapiensENSP0000037362093.019286.911lates_calcariferENSLCAP0001005988986.807881.1075
ENSG00000144381homo_sapiensENSP0000037362094.764489.3543xenopus_tropicalisENSXETP0000009295387.864182.8479
ENSG00000144381homo_sapiensENSP0000037362096.858693.0192chrysemys_picta_belliiENSCPBP0000003121697.368493.5088
ENSG00000144381homo_sapiensENSP0000037362096.160691.9721sphenodon_punctatusENSSPUP0000000046596.160691.9721
ENSG00000144381homo_sapiensENSP0000037362090.226985.5148crocodylus_porosusENSCPRP0000501309889.137984.4828
ENSG00000144381homo_sapiensENSP0000037362096.858693.5428laticauda_laticaudataENSLLTP0000000122085.780582.8439
ENSG00000144381homo_sapiensENSP0000037362096.509693.3682notechis_scutatusENSNSUP0000001895896.678393.5315
ENSG00000144381homo_sapiensENSP0000037362096.858693.5428pseudonaja_textilisENSPTXP0000000605697.02893.7063
ENSG00000144381homo_sapiensENSP0000037362097.731294.0663gallus_gallusENSGALP0001002108997.731294.0663
ENSG00000144381homo_sapiensENSP0000037362097.556794.0663meleagris_gallopavoENSMGAP0000000718789.727186.5169
ENSG00000144381homo_sapiensENSP0000037362097.556794.0663serinus_canariaENSSCAP0000000340097.556794.0663
ENSG00000144381homo_sapiensENSP0000037362097.382293.8918parus_majorENSPMJP0000000457397.382293.8918
ENSG00000144381homo_sapiensENSP0000037362097.382294.2408anolis_carolinensisENSACAP0000000937782.422579.7637
ENSG00000144381homo_sapiensENSP0000037362093.193787.26neolamprologus_brichardiENSNBRP0000002070292.869686.9565
ENSG00000144381homo_sapiensENSP0000037362096.858693.7173naja_najaENSNNAP0000001049597.02893.8811
ENSG00000144381homo_sapiensENSP0000037362097.033292.6702podarcis_muralisENSPMRP0000000734697.37392.9947
ENSG00000144381homo_sapiensENSP0000037362097.207793.0192podarcis_muralisENSPMRP0000000775791.461487.5205
ENSG00000144381homo_sapiensENSP0000037362097.033293.5428geospiza_fortisENSGFOP0000000047497.033293.5428
ENSG00000144381homo_sapiensENSP0000037362097.382293.7173taeniopygia_guttataENSTGUP0000001087397.382293.7173
ENSG00000144381homo_sapiensENSP0000037362095.462589.1798erpetoichthys_calabaricusENSECRP0000002755495.629489.3357
ENSG00000144381homo_sapiensENSP0000037362089.179882.548kryptolebias_marmoratusENSKMAP0000000515682.419476.2903
ENSG00000144381homo_sapiensENSP0000037362096.858693.5428salvator_merianaeENSSMRP0000002624297.368494.0351
ENSG00000144381homo_sapiensENSP0000037362093.717386.911dicentrarchus_labraxENSDLAP0000507530792.746186.0104
ENSG00000144381homo_sapiensENSP0000037362094.066387.26amphiprion_perculaENSAPEP0000001827088.360781.9672
ENSG00000144381homo_sapiensENSP0000037362093.717386.562oryzias_sinensisENSOSIP0000000780493.391386.2609
ENSG00000144381homo_sapiensENSP0000037362096.335192.8447pelodiscus_sinensisENSPSIP0000002022296.672593.1699
ENSG00000144381homo_sapiensENSP0000037362096.858693.0192gopherus_evgoodeiENSGEVP0000502165597.368493.5088
ENSG00000144381homo_sapiensENSP0000037362096.684193.1937chelonoidis_abingdoniiENSCABP0000000930297.19393.6842
ENSG00000144381homo_sapiensENSP0000037362094.240887.26seriola_dumeriliENSSDUP0000002405793.7586.8056
ENSG00000144381homo_sapiensENSP0000037362093.368285.1658cottoperca_gobioENSCGOP0000000640092.400784.2832
ENSG00000144381homo_sapiensENSP0000037362097.556793.8918struthio_camelus_australisENSSCUP0000000149497.556793.8918
ENSG00000144381homo_sapiensENSP0000037362097.556794.5899anser_brachyrhynchusENSABRP0000000955797.556794.5899
ENSG00000144381homo_sapiensENSP0000037362092.844785.8639gasterosteus_aculeatusENSGACP0000001187091.408984.5361
ENSG00000144381homo_sapiensENSP0000037362085.165879.5812cynoglossus_semilaevisENSCSEP0000000601891.729385.7143
ENSG00000144381homo_sapiensENSP0000037362093.717387.7836poecilia_formosaENSPFOP0000000005493.391387.4783
ENSG00000144381homo_sapiensENSP0000037362094.415488.4817myripristis_murdjanENSMMDP0000502872091.23185.4975
ENSG00000144381homo_sapiensENSP0000037362092.495684.4677sander_luciopercaENSSLUP0000003925388.333380.6667
ENSG00000144381homo_sapiensENSP0000037362097.905894.2408strigops_habroptilaENSSHBP0000502309682.579.4118
ENSG00000144381homo_sapiensENSP0000037362094.240887.26amphiprion_ocellarisENSAOCP0000000141688.524681.9672
ENSG00000144381homo_sapiensENSP0000037362096.684193.1937terrapene_carolina_triunguisENSTMTP0000001233697.19393.6842
ENSG00000144381homo_sapiensENSP0000037362093.193786.0384hucho_huchoENSHHUP0000008936893.193786.0384
ENSG00000144381homo_sapiensENSP0000037362093.542886.562hucho_huchoENSHHUP0000004186493.055686.1111
ENSG00000144381homo_sapiensENSP0000037362093.193787.4346betta_splendensENSBSLP0000005197081.651476.6055
ENSG00000144381homo_sapiensENSP0000037362094.066387.0855pygocentrus_nattereriENSPNAP0000000161893.739186.7826
ENSG00000144381homo_sapiensENSP0000037362093.542886.7365anabas_testudineusENSATEP0000004693991.311884.6678
ENSG00000144381homo_sapiensENSP0000037362081.849969.808ciona_savignyiENSCSAVP0000000118778.559567.0017
ENSG00000144381homo_sapiensENSP0000037362073.298456.1955saccharomyces_cerevisiaeYLR259C73.426656.2937
ENSG00000144381homo_sapiensENSP0000037362094.240887.26seriola_lalandi_dorsalisENSSLDP0000002517493.7586.8056
ENSG00000144381homo_sapiensENSP0000037362088.307281.1518labrus_bergyltaENSLBEP0000002922388.771981.5789
ENSG00000144381homo_sapiensENSP0000037362085.340379.0576pundamilia_nyerereiENSPNYP0000001990790.221483.5793
ENSG00000144381homo_sapiensENSP0000037362093.891887.4346mastacembelus_armatusENSMAMP0000003856091.341385.0594
ENSG00000144381homo_sapiensENSP0000037362093.717387.4346stegastes_partitusENSSPAP0000001375393.391387.1304
ENSG00000144381homo_sapiensENSP0000037362081.675473.6475acanthochromis_polyacanthusENSAPOP0000002586386.827578.2931
ENSG00000144381homo_sapiensENSP0000037362079.930272.6003acanthochromis_polyacanthusENSAPOP0000002741587.907979.8465
ENSG00000144381homo_sapiensENSP0000037362093.891887.26acanthochromis_polyacanthusENSAPOP0000003032988.341582.1018
ENSG00000144381homo_sapiensENSP0000037362097.731294.0663aquila_chrysaetos_chrysaetosENSACCP0002000328497.731294.0663
ENSG00000144381homo_sapiensENSP0000037362094.066388.1326nothobranchius_furzeriENSNFUP0001500991688.21682.6514
ENSG00000144381homo_sapiensENSP0000037362093.542886.911cyprinodon_variegatusENSCVAP0000002152193.217486.6087
ENSG00000144381homo_sapiensENSP0000037362094.066387.4346denticeps_clupeoidesENSDCDP0000001429889.983383.6394
ENSG00000144381homo_sapiensENSP0000037362091.099583.4206denticeps_clupeoidesENSDCDP0000000250991.418683.7128
ENSG00000144381homo_sapiensENSP0000037362093.717386.7365larimichthys_croceaENSLCRP0000504320592.746185.8377
ENSG00000144381homo_sapiensENSP0000037362093.193787.4346takifugu_rubripesENSTRUP0000003986892.869687.1304
ENSG00000144381homo_sapiensENSP0000037362097.556794.0663ficedula_albicollisENSFALP0000000445194.107790.7407
ENSG00000144381homo_sapiensENSP0000037362093.891886.0384hippocampus_comesENSHCOP0000002473093.402885.5903
ENSG00000144381homo_sapiensENSP0000037362093.717386.562cyprinus_carpio_carpioENSCCRP0000010133993.391386.2609
ENSG00000144381homo_sapiensENSP0000037362094.066386.7365cyprinus_carpio_carpioENSCCRP0000014029487.216880.4207
ENSG00000144381homo_sapiensENSP0000037362097.556793.8918coturnix_japonicaENSCJPP0000500424497.556793.8918
ENSG00000144381homo_sapiensENSP0000037362093.717387.7836poecilia_latipinnaENSPLAP0000000112093.391387.4783
ENSG00000144381homo_sapiensENSP0000037362093.891886.562sinocyclocheilus_grahamiENSSGRP0000010583493.565286.2609
ENSG00000144381homo_sapiensENSP0000037362094.589987.6091sinocyclocheilus_grahamiENSSGRP0000010546991.554184.7973
ENSG00000144381homo_sapiensENSP0000037362092.844787.0855maylandia_zebraENSMZEP0000502852892.521786.7826
ENSG00000144381homo_sapiensENSP0000037362093.542887.4346tetraodon_nigroviridisENSTNIP0000001448193.217487.1304
ENSG00000144381homo_sapiensENSP0000037362094.415487.4346paramormyrops_kingsleyaeENSPKIP0000001317494.250987.2822
ENSG00000144381homo_sapiensENSP0000037362091.099582.199scleropages_formosusENSSFOP0001501721392.063583.0688
ENSG00000144381homo_sapiensENSP0000037362093.717387.26scleropages_formosusENSSFOP0001504831192.746186.3558
ENSG00000144381homo_sapiensENSP0000037362096.160690.4014leptobrachium_leishanenseENSLLEP0000004150295.493989.7747
ENSG00000144381homo_sapiensENSP0000037362091.972184.8168scophthalmus_maximusENSSMAP0000005156390.862183.7931
ENSG00000144381homo_sapiensENSP0000037362093.717387.26oryzias_melastigmaENSOMEP0000001759193.391386.9565

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0001530enables lipopolysaccharide binding1IDAHomo_sapiens(9606)Function
GO:0002039enables p53 binding1IPIHomo_sapiens(9606)Function
GO:0002755involved_in MyD88-dependent toll-like receptor signaling pathway1IDAHomo_sapiens(9606)Process
GO:0002842involved_in positive regulation of T cell mediated immune response to tumor cell1IDAHomo_sapiens(9606)Process
GO:0003688enables DNA replication origin binding1ISSHomo_sapiens(9606)Function
GO:0003697enables single-stranded DNA binding1ISSHomo_sapiens(9606)Function
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003725enables double-stranded RNA binding1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IEAHomo_sapiens(9606)Function
GO:0005615located_in extracellular space1IDAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005739located_in mitochondrion1IDAHomo_sapiens(9606)Component
GO:0005743is_active_in mitochondrial inner membrane2IBA,ISSHomo_sapiens(9606)Component
GO:0005759is_active_in mitochondrial matrix3IBA,IDA,TASHomo_sapiens(9606)Component
GO:0005769located_in early endosome1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0005886located_in plasma membrane1IDAHomo_sapiens(9606)Component
GO:0005905located_in clathrin-coated pit1IDAHomo_sapiens(9606)Component
GO:0006457involved_in protein folding1IBAHomo_sapiens(9606)Process
GO:0006458involved_in de novo protein folding1ISSHomo_sapiens(9606)Process
GO:0006919involved_in activation of cysteine-type endopeptidase activity involved in apoptotic process1IDAHomo_sapiens(9606)Process
GO:0006986involved_in response to unfolded protein1IDAHomo_sapiens(9606)Process
GO:0008035enables high-density lipoprotein particle binding1IDAHomo_sapiens(9606)Function
GO:0008637involved_in apoptotic mitochondrial changes1IBAHomo_sapiens(9606)Process
GO:0009409involved_in response to cold1ISSHomo_sapiens(9606)Process
GO:0009986located_in cell surface1IDAHomo_sapiens(9606)Component
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0016853enables isomerase activity1IEAHomo_sapiens(9606)Function
GO:0016887enables ATP hydrolysis activity1ISSHomo_sapiens(9606)Function
GO:0019899enables enzyme binding1IPIHomo_sapiens(9606)Function
GO:0030135located_in coated vesicle1IDAHomo_sapiens(9606)Component
GO:0030141located_in secretory granule1ISSHomo_sapiens(9606)Component
GO:0031625enables ubiquitin protein ligase binding1IPIHomo_sapiens(9606)Function
GO:0032727involved_in positive regulation of interferon-alpha production2IBA,IDAHomo_sapiens(9606)Process
GO:0032729involved_in positive regulation of type II interferon production4IBA,IDA,ISSHomo_sapiens(9606)Process
GO:0032733involved_in positive regulation of interleukin-10 production1IDAHomo_sapiens(9606)Process
GO:0032735involved_in positive regulation of interleukin-12 production1IDAHomo_sapiens(9606)Process
GO:0032755involved_in positive regulation of interleukin-6 production2IBA,IDAHomo_sapiens(9606)Process
GO:0032991part_of protein-containing complex1IDAHomo_sapiens(9606)Component
GO:0034185enables apolipoprotein binding1IPIHomo_sapiens(9606)Function
GO:0034186enables apolipoprotein A-I binding1IPIHomo_sapiens(9606)Function
GO:0034514involved_in mitochondrial unfolded protein response1IBAHomo_sapiens(9606)Process
GO:0042026involved_in protein refolding1IDAHomo_sapiens(9606)Process
GO:0042100involved_in B cell proliferation1IDAHomo_sapiens(9606)Process
GO:0042110involved_in T cell activation2IBA,IDAHomo_sapiens(9606)Process
GO:0042113involved_in B cell activation1IDAHomo_sapiens(9606)Process
GO:0043032involved_in positive regulation of macrophage activation1IDAHomo_sapiens(9606)Process
GO:0043065involved_in positive regulation of apoptotic process1IMPHomo_sapiens(9606)Process
GO:0043066involved_in negative regulation of apoptotic process1IMPHomo_sapiens(9606)Process
GO:0044406NOT involved_in adhesion of symbiont to host1IDAHomo_sapiens(9606)Process
GO:0045041involved_in protein import into mitochondrial intermembrane space1IBAHomo_sapiens(9606)Process
GO:0046696part_of lipopolysaccharide receptor complex1IDAHomo_sapiens(9606)Component
GO:0048291involved_in isotype switching to IgG isotypes1IDAHomo_sapiens(9606)Process
GO:0050821involved_in protein stabilization2IMP,ISSHomo_sapiens(9606)Process
GO:0050870involved_in positive regulation of T cell activation3IBA,IDA,ISSHomo_sapiens(9606)Process
GO:0051082enables unfolded protein binding2IC,ISSHomo_sapiens(9606)Function
GO:0051087enables protein-folding chaperone binding2IBA,IPIHomo_sapiens(9606)Function
GO:0051131involved_in chaperone-mediated protein complex assembly1ISSHomo_sapiens(9606)Process
GO:0051604involved_in protein maturation1ISSHomo_sapiens(9606)Process
GO:0051702involved_in biological process involved in interaction with symbiont1IMPHomo_sapiens(9606)Process
GO:0070062located_in extracellular exosome2HDA,IDAHomo_sapiens(9606)Component
GO:0097225located_in sperm midpiece1IMPHomo_sapiens(9606)Component
GO:0097524located_in sperm plasma membrane1IEAHomo_sapiens(9606)Component
GO:0098761involved_in cellular response to interleukin-71IEAHomo_sapiens(9606)Process
GO:0140494located_in migrasome1IEAHomo_sapiens(9606)Component
GO:0140662enables ATP-dependent protein folding chaperone1IEAHomo_sapiens(9606)Function

Expression