Ensembl ID ENSG00000144381 Gene ID 3329 Accession 5261
Gene Symbol HSPD1 Alias HLD4;CPN60;GROEL;HSP60;HSP65;SPG13;HSP-60;HuCHA60 Full Name heat shock protein family D (Hsp60) member 1
Position 2 : 197486584 - 197516737 Length 30154 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq, Jun 2010]

ENSG00000144381 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000144381 HSPD1 0.64 1.02e-19 BRCA
ENSG00000144381 HSPD1 1.26 5.58e-42 COAD
ENSG00000144381 HSPD1 1.56 2.86e-60 LUSC
ENSG00000144381 HSPD1 0.63 7.93e-16 PRAD
ENSG00000144381 HSPD1 1.27 1.88e-22 STAD
ENSG00000144381 HSPD1 0.84 4.89e-13 UCEC
ENSG00000144381 HSPD1 1.29 9.75e-42 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000144381 HSPD1 tumor 10048972
ENSG00000144381 HSPD1 tumours 10663613
ENSG00000144381 HSPD1 tumor 10725457
ENSG00000144381 HSPD1 tumor 10776793
ENSG00000144381 HSPD1 prostate cancer 11156417
ENSG00000144381 HSPD1 tumor 11429196
ENSG00000144381 HSPD1 tumors of the nervous system 11458278
ENSG00000144381 HSPD1 colon cancer 11705730
ENSG00000144381 HSPD1 tumour 11882035
ENSG00000144381 HSPD1 cancers 12777205
ENSG00000144381 HSPD1 cervical cancer 14634555
ENSG00000144381 HSPD1 tumor 15546885
ENSG00000144381 HSPD1 tumor 15592361
ENSG00000144381 HSPD1 tumor 1567788
ENSG00000144381 HSPD1 tumour 15679807
ENSG00000144381 HSPD1 hepatocellular cancer 15878334
ENSG00000144381 HSPD1 cancer 15880780
ENSG00000144381 HSPD1 breast cancer 16033770
ENSG00000144381 HSPD1 tumor 16055092
ENSG00000144381 HSPD1 colorectal cancer 16308103
ENSG00000144381 HSPD1 tumor 16619219
ENSG00000144381 HSPD1 prostate cancer 16705742
ENSG00000144381 HSPD1 cancer 17048249
ENSG00000144381 HSPD1 tumors 1709051
ENSG00000144381 HSPD1 cancer 17457039
ENSG00000144381 HSPD1 tumor 17905417
ENSG00000144381 HSPD1 cancer 17920521
ENSG00000144381 HSPD1 tumor 18086682
ENSG00000144381 HSPD1 tumor 18478617
ENSG00000144381 HSPD1 cancer 18497565
ENSG00000144381 HSPD1 tumor 18646040
ENSG00000144381 HSPD1 breast cancer 18683965
ENSG00000144381 HSPD1 Gastric cancer 19004824
ENSG00000144381 HSPD1 cancer 19109096
ENSG00000144381 HSPD1 tumor 19203381
ENSG00000144381 HSPD1 tumor 19309015
ENSG00000144381 HSPD1 gastric cancer 19450936
ENSG00000144381 HSPD1 Cervical Cancer 19568603
ENSG00000144381 HSPD1 colorectal cancer 19635199
ENSG00000144381 HSPD1 tumor 19654875
ENSG00000144381 HSPD1 tumor 19701498
ENSG00000144381 HSPD1 tumor 19714222
ENSG00000144381 HSPD1 ovarian cancer 20082317
ENSG00000144381 HSPD1 Tumor 20169074
ENSG00000144381 HSPD1 Cancer 20351780
ENSG00000144381 HSPD1 lung cancer 20501758
ENSG00000144381 HSPD1 cancer 20580690
ENSG00000144381 HSPD1 ovarian cancer 20625496
ENSG00000144381 HSPD1 tumor 20631313
ENSG00000144381 HSPD1 tumor 20708221
ENSG00000144381 HSPD1 tumor 20977276
ENSG00000144381 HSPD1 tumor 20978188
ENSG00000144381 HSPD1 cancer 21113302
ENSG00000144381 HSPD1 colorectal cancer 21196380
ENSG00000144381 HSPD1 head and neck-cancer 21559731
ENSG00000144381 HSPD1 cancer 21642380
ENSG00000144381 HSPD1 tumor 21671464
ENSG00000144381 HSPD1 cancer 21822415
ENSG00000144381 HSPD1 gastric cancer 21846196
ENSG00000144381 HSPD1 cancer 21898240
ENSG00000144381 HSPD1 cancer 21969171
ENSG00000144381 HSPD1 colorectal cancer 21973086
ENSG00000144381 HSPD1 tumors 22083493
ENSG00000144381 HSPD1 colorectal cancer 22125622
ENSG00000144381 HSPD1 tumors 22191045
ENSG00000144381 HSPD1 breast cancer 22357162
ENSG00000144381 HSPD1 tumor 22539317
ENSG00000144381 HSPD1 tumours 22549151
ENSG00000144381 HSPD1 Tumor 22848686
ENSG00000144381 HSPD1 tumor 22896634
ENSG00000144381 HSPD1 cancer 22920896
ENSG00000144381 HSPD1 breast cancer 23017679
ENSG00000144381 HSPD1 cancer 23092316
ENSG00000144381 HSPD1 tumor 23118872
ENSG00000144381 HSPD1 tumors 23140567
ENSG00000144381 HSPD1 cancer 23276948
ENSG00000144381 HSPD1 tumors 23341740
ENSG00000144381 HSPD1 ovarian cancer 23429486
ENSG00000144381 HSPD1 prostate cancer 23661456
ENSG00000144381 HSPD1 tumor 23807299
ENSG00000144381 HSPD1 cancer 24015183
ENSG00000144381 HSPD1 Tumor 24027419
ENSG00000144381 HSPD1 cancer 24066722
ENSG00000144381 HSPD1 ovarian cancer 24618330
ENSG00000144381 HSPD1 cancer 24675290
ENSG00000144381 HSPD1 tumor 24710494
ENSG00000144381 HSPD1 cancer 24801752
ENSG00000144381 HSPD1 cancer 24830947
ENSG00000144381 HSPD1 GBM 24838487
ENSG00000144381 HSPD1 AML 24885082
ENSG00000144381 HSPD1 breast cancer 25143958
ENSG00000144381 HSPD1 tumor 25188891
ENSG00000144381 HSPD1 gastric cancer 25207654
ENSG00000144381 HSPD1 cancers 25258164
ENSG00000144381 HSPD1 tumor 25413103
ENSG00000144381 HSPD1 breast cancer 25454514
ENSG00000144381 HSPD1 cancer 25487021
ENSG00000144381 HSPD1 breast cancer 25541910
ENSG00000144381 HSPD1 cancer 25675302
ENSG00000144381 HSPD1 large bowel cancer 26060090
ENSG00000144381 HSPD1 cancers 26074449
ENSG00000144381 HSPD1 colon cancer 26082068
ENSG00000144381 HSPD1 Cancer 26297309
ENSG00000144381 HSPD1 tumor 26442925
ENSG00000144381 HSPD1 HNSCC 26452026
ENSG00000144381 HSPD1 tumor 26595676
ENSG00000144381 HSPD1 breast cancer 26672742
ENSG00000144381 HSPD1 lung cancer 26721444
ENSG00000144381 HSPD1 tumor 26812922
ENSG00000144381 HSPD1 tumor 26862520
ENSG00000144381 HSPD1 cancer 26918043
ENSG00000144381 HSPD1 tumor 26937234
ENSG00000144381 HSPD1 tumor 27379206
ENSG00000144381 HSPD1 large bowel cancer 27491302
ENSG00000144381 HSPD1 cancer 27667530
ENSG00000144381 HSPD1 tumor 27677587
ENSG00000144381 HSPD1 tumor 27836734
ENSG00000144381 HSPD1 cancer 28183315
ENSG00000144381 HSPD1 cancer 28212901
ENSG00000144381 HSPD1 Colon Cancer 28261350
ENSG00000144381 HSPD1 tumor 28468249
ENSG00000144381 HSPD1 breast cancer 28591216
ENSG00000144381 HSPD1 cancer 28718351
ENSG00000144381 HSPD1 cancers 28774748
ENSG00000144381 HSPD1 tumor 28978099
ENSG00000144381 HSPD1 tumor 28978152
ENSG00000144381 HSPD1 tumor 29079220
ENSG00000144381 HSPD1 tumor 29080556
ENSG00000144381 HSPD1 Cancer 29177667
ENSG00000144381 HSPD1 tumor 29246022
ENSG00000144381 HSPD1 tumor 29423396
ENSG00000144381 HSPD1 tumor 29521101
ENSG00000144381 HSPD1 Ovarian Tumors 29524832
ENSG00000144381 HSPD1 cancer 29672920
ENSG00000144381 HSPD1 prostate cancer 29682763
ENSG00000144381 HSPD1 tumours 29702669
ENSG00000144381 HSPD1 cancers 29732373
ENSG00000144381 HSPD1 tumor 29904027
ENSG00000144381 HSPD1 breast cancer 29954368
ENSG00000144381 HSPD1 tumor 30055129
ENSG00000144381 HSPD1 GBM 30111643
ENSG00000144381 HSPD1 tumor 30189598
ENSG00000144381 HSPD1 tumour 30200516
ENSG00000144381 HSPD1 tumors of the bladder 30337218
ENSG00000144381 HSPD1 breast cancer 30365075
ENSG00000144381 HSPD1 tumor 30469470
ENSG00000144381 HSPD1 tumor 30609639
ENSG00000144381 HSPD1 tumor 30800066
ENSG00000144381 HSPD1 tumor 30862036
ENSG00000144381 HSPD1 prostate cancer 30897525
ENSG00000144381 HSPD1 cancer 30950146
ENSG00000144381 HSPD1 tumor 31084385
ENSG00000144381 HSPD1 cancer 31177901
ENSG00000144381 HSPD1 oral cancer 31222140
ENSG00000144381 HSPD1 ovarian tumors 31477750
ENSG00000144381 HSPD1 gastric cancer 31523402
ENSG00000144381 HSPD1 digestive system cancers 31625354
ENSG00000144381 HSPD1 cancer 31673102
ENSG00000144381 HSPD1 tumors 31897148
ENSG00000144381 HSPD1 ovarian cancer 8098058
ENSG00000144381 HSPD1 tumour 8738959
ENSG00000144381 HSPD1 tumour 9218839
ENSG00000144381 HSPD1 tumor 9781640
ENSG00000144381 HSPD1 tumors 9850087
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000144381 HSPD1 MESO 0.0088 high
ENSG00000144381 HSPD1 SARC 0.028 high
ENSG00000144381 HSPD1 STAD 0.034 low
ENSG00000144381 HSPD1 PAAD 0.022 high
ENSG00000144381 HSPD1 UCEC 1e-04 high
ENSG00000144381 HSPD1 THCA 0.025 high
ENSG00000144381 HSPD1 ACC 0.0016 high
ENSG00000144381 HSPD1 LUSC 0.022 low
ENSG00000144381 HSPD1 HNSC 0.0026 high
ENSG00000144381 HSPD1 READ 0.03 low
ENSG00000144381 HSPD1 KICH 0.005 high
ENSG00000144381 HSPD1 LUAD 0.00041 high
ENSG00000144381 HSPD1 PCPG 0.0064 high
ENSG00000144381 HSPD1 THYM 0.042 high
ENSG00000144381 HSPD1 BRCA 0.0065 high
ENSG00000144381 HSPD1 OV 0.0063 low
ENSG00000144381 HSPD1 KIRC 0.018 low
ENSG00000144381 HSPD1 PRAD 0.004 high
ENSG00000144381 HSPD1 CESC 0.014 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000144381 HSPD1 CESC Amp 1.353175 0.154654 0.546268 0.166102
ENSG00000144381 HSPD1 KIRP Amp 1.597657 0.090905 0.688447 0.180556
ENSG00000144381 HSPD1 HNSC Amp 0.925170 0.121931 0.483573 0.160920
ENSG00000144381 HSPD1 BLCA Del 0.965128 0.081729 0.362350 0.321078