Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000144218 Gene ID 3899 Accession 6473
Symbol AFF3 Alias KINS;LAF4;MLLT2-like Full Name ALF transcription elongation factor 3
Status Confidence Length 597172 bases Strand Minus strand
Position 2 : 99545419 - 100142590 RNA binding domain AF-4
Summary This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000500616 AF-4 PF05110 2.3e-135 1
ENSP00000500616 AF-4 PF05110 2.3e-135 2
ENSP00000317421 AF-4 PF05110 9.4e-134 1
ENSP00000317421 AF-4 PF05110 9.4e-134 2
ENSP00000387207 AF-4 PF05110 9.4e-134 1
ENSP00000387207 AF-4 PF05110 9.4e-134 2
ENSP00000500419 AF-4 PF05110 9.4e-134 1
ENSP00000500419 AF-4 PF05110 9.4e-134 2
ENSP00000386834 AF-4 PF05110 1e-133 1
ENSP00000386834 AF-4 PF05110 1e-133 2
ENSP00000500310 AF-4 PF05110 2.1e-86 1
ENSP00000500310 AF-4 PF05110 2.1e-86 2
ENSP00000414099 AF-4 PF05110 6.5e-59 1
ENSP00000406484 AF-4 PF05110 3.6e-50 1
ENSP00000396582 AF-4 PF05110 9.3e-49 1
ENSP00000399795 AF-4 PF05110 7.9e-48 1
ENSP00000500612 AF-4 PF05110 1.9e-46 1
ENSP00000411383 AF-4 PF05110 7.8e-46 1
ENSP00000395068 AF-4 PF05110 2.7e-41 1
ENSP00000500634 AF-4 PF05110 1.2e-36 1
ENSP00000500860 AF-4 PF05110 1.2e-36 1
ENSP00000393732 AF-4 PF05110 1.8e-30 1
ENSP00000500270 AF-4 PF05110 9.8e-06 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
23028342 New susceptibility loci associated with kidney disease in type 1 diabetes. Niina Sandholm 2012-09-01 PLoS genetics
36001653 AFF3, a susceptibility factor for autoimmune diseases, is a molecular facilitator of immunoglobulin class switch recombination. Shin-Ichi Tsukumo 2022-08-26 Science advances

Transcripts

Name Transcript ID bp Protein Translation ID
AFF3-202 ENST00000409236 9849 1226aa ENSP00000387207
AFF3-221 ENST00000672756 10070 1226aa ENSP00000500419
AFF3-201 ENST00000317233 8135 1226aa ENSP00000317421
AFF3-216 ENST00000671937 5267 134aa ENSP00000500817
AFF3-213 ENST00000445815 2385 580aa ENSP00000416685
AFF3-203 ENST00000409579 4342 1251aa ENSP00000386834
AFF3-219 ENST00000672204 2060 608aa ENSP00000500616
AFF3-209 ENST00000430789 730 179aa ENSP00000414099
AFF3-220 ENST00000672269 2488 379aa ENSP00000500310
AFF3-227 ENST00000673529 634 No protein -
AFF3-215 ENST00000498090 1673 No protein -
AFF3-210 ENST00000432037 559 161aa ENSP00000406484
AFF3-206 ENST00000423966 598 165aa ENSP00000396582
AFF3-212 ENST00000441400 543 128aa ENSP00000399795
AFF3-226 ENST00000673328 588 143aa ENSP00000500612
AFF3-207 ENST00000424600 551 114aa ENSP00000411383
AFF3-205 ENST00000416492 545 99aa ENSP00000395068
AFF3-225 ENST00000673232 472 115aa ENSP00000500634
AFF3-218 ENST00000672197 589 115aa ENSP00000500860
AFF3-211 ENST00000440445 591 103aa ENSP00000393732
AFF3-223 ENST00000672857 595 43aa ENSP00000500270
AFF3-217 ENST00000672047 369 No protein -
AFF3-204 ENST00000415384 574 54aa ENSP00000407448
AFF3-208 ENST00000427118 528 17aa ENSP00000416131
AFF3-224 ENST00000672999 567 No protein -
AFF3-214 ENST00000483600 852 No protein -
AFF3-222 ENST00000672822 628 No protein -
AFF3-228 ENST00000683540 550 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
3925Apolipoproteins E1.6456952159278E-1917903299
3935Apolipoproteins E6.24225405203388E-1917903299
7978Uric Acid6.8050755579474E-517903292
10069Exercise Test5.35968467572356E-617903301
10078Exercise Test3.30381457425335E-717903301
14918Hemoglobin A, Glycosylated5.2110000E-00519875614
14919Hemoglobin A, Glycosylated2.6990000E-00619875614
14928Hemoglobin A, Glycosylated2.6740000E-00619875614
14938Hemoglobin A, Glycosylated2.8170000E-00519875614
14939Hemoglobin A, Glycosylated3.3130000E-00619875614
14940Hemoglobin A, Glycosylated8.7910000E-00519875614
14943Hemoglobin A, Glycosylated6.3120000E-00519875614
17876Body Weights and Measures1.249e-00517658951
24200Body Fat Distribution5.5560000E-005-
25957Coronary Artery Disease7.0010000E-005-
25964Coronary Artery Disease1.0900000E-005-
25965Coronary Artery Disease4.8670000E-006-
26004Coronary Artery Disease4.6730000E-006-
26013Coronary Artery Disease1.3400000E-005-
26519Blood Pressure6.0560000E-005-
26520Blood Pressure3.9990000E-005-
26523Blood Pressure8.8520000E-005-
26524Blood Pressure1.2260000E-005-
26554Blood Pressure6.8850000E-005-
34518Platelet Function Tests9.5100000E-006-
40927Platelet Function Tests1.1541300E-005-
63366Paliperidone Palmitate2E-627846195
63367Schizophrenia2E-627846195
65805Diabetic Nephropathies1E-823028342
65859Diabetic Nephropathies3E-723028342
68222Education2E-925201988
76115Marijuana Abuse2E-627028160
82896Education1E-927225129
85313Education4E-1927225129
85769Education9E-2827225129
90032Education2E-1127225129
96207Arthritis, Rheumatoid2E-824782177
102066Diabetic Nephropathies4E-727647854
102067Renal Insufficiency, Chronic4E-727647854
102794Education5E-1123722424
106157Arthritis, Rheumatoid1E-1420453842

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000144218homo_sapiensENSP0000035948950.800936.9947homo_sapiensENSP0000050041954.32339.5595
ENSG00000144218homo_sapiensENSP0000026534352.278635.3396homo_sapiensENSP0000050041949.592233.5237
ENSG00000144218homo_sapiensENSP0000037857845.484430.5419homo_sapiensENSP0000050041945.187630.3426

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000144218homo_sapiensENSP0000050041994.535193.9641nomascus_leucogenysENSNLEP0000001741397.1596.5633
ENSG00000144218homo_sapiensENSP0000050041995.024594.7798pan_paniscusENSPPAP0000001791597.734997.4832
ENSG00000144218homo_sapiensENSP0000050041999.265998.8581pongo_abeliiENSPPYP0000001348797.282296.8825
ENSG00000144218homo_sapiensENSP0000050041998.287197.9608pan_troglodytesENSPTRP0000002104397.729197.4047
ENSG00000144218homo_sapiensENSP0000050041999.755399.5106gorilla_gorillaENSGGOP0000002873797.761897.522
ENSG00000144218homo_sapiensENSP0000050041971.288761.9086ornithorhynchus_anatinusENSOANP0000005350273.199363.5678
ENSG00000144218homo_sapiensENSP0000050041987.765180.3426sarcophilus_harrisiiENSSHAP0000003621873.597867.3735
ENSG00000144218homo_sapiensENSP0000050041968.923362.4796notamacropus_eugeniiENSMEUP0000001271871.008464.3698
ENSG00000144218homo_sapiensENSP0000050041950.489448.124choloepus_hoffmanniENSCHOP0000000213349.639147.3136
ENSG00000144218homo_sapiensENSP0000050041921.61519.9837dasypus_novemcinctusENSDNOP0000002059977.712671.8475
ENSG00000144218homo_sapiensENSP0000050041959.298555.5465dasypus_novemcinctusENSDNOP0000003193789.975384.2822
ENSG00000144218homo_sapiensENSP0000050041977.406273.8173erinaceus_europaeusENSEEUP0000000447086.116182.1234
ENSG00000144218homo_sapiensENSP0000050041962.479659.9511echinops_telfairiENSETEP0000001017062.124959.6107
ENSG00000144218homo_sapiensENSP0000050041998.205596.9005callithrix_jacchusENSCJAP0000001855696.24394.964
ENSG00000144218homo_sapiensENSP0000050041999.102898.5318cercocebus_atysENSCATP0000004565297.122396.5628
ENSG00000144218homo_sapiensENSP0000050041995.024594.3719macaca_fascicularisENSMFAP0000004847195.413694.7584
ENSG00000144218homo_sapiensENSP0000050041998.858198.2871macaca_mulattaENSMMUP0000006625798.938898.3673
ENSG00000144218homo_sapiensENSP0000050041980.995179.9347macaca_nemestrinaENSMNEP0000001530397.640196.3618
ENSG00000144218homo_sapiensENSP0000050041999.102898.5318papio_anubisENSPANP0000003352897.122396.5628
ENSG00000144218homo_sapiensENSP0000050041970.554669.739mandrillus_leucophaeusENSMLEP0000003530896.756195.6376
ENSG00000144218homo_sapiensENSP0000050041990.048986.1338tursiops_truncatusENSTTRP0000001334590.048986.1338
ENSG00000144218homo_sapiensENSP0000050041993.148590.2936vulpes_vulpesENSVVUP0000004018490.923688.1369
ENSG00000144218homo_sapiensENSP0000050041992.822288.1729mus_spretusMGP_SPRETEiJ_P001827292.822288.1729
ENSG00000144218homo_sapiensENSP0000050041992.985390.1305equus_asinusENSEASP0000502679693.137390.2778
ENSG00000144218homo_sapiensENSP0000050041993.066988.907capra_hircusENSCHIP0000003284292.915388.7622
ENSG00000144218homo_sapiensENSP0000050041992.495988.4176loxodonta_africanaENSLAFP0000001077691.377987.3489
ENSG00000144218homo_sapiensENSP0000050041996.574293.3932panthera_leoENSPLOP0000001930194.568791.4537
ENSG00000144218homo_sapiensENSP0000050041991.843488.1729ailuropoda_melanoleucaENSAMEP0000001390787.831584.3214
ENSG00000144218homo_sapiensENSP0000050041986.4681.1582bos_indicus_hybridENSBIXP0000503273783.794578.6561
ENSG00000144218homo_sapiensENSP0000050041990.619986.46oryctolagus_cuniculusENSOCUP0000002067385.924281.9799
ENSG00000144218homo_sapiensENSP0000050041995.187692.0065equus_caballusENSECAP0000008368391.962288.8889
ENSG00000144218homo_sapiensENSP0000050041995.432392.6591canis_lupus_familiarisENSCAFP0084502352293.690.88
ENSG00000144218homo_sapiensENSP0000050041996.574293.3932panthera_pardusENSPPRP0000002394994.568791.4537
ENSG00000144218homo_sapiensENSP0000050041976.590572.9201cavia_porcellusENSCPOP0000000571891.520587.1345
ENSG00000144218homo_sapiensENSP0000050041996.24893.0669felis_catusENSFCAP0000002460394.324591.207
ENSG00000144218homo_sapiensENSP0000050041952.283947.4715monodelphis_domesticaENSMODP0000004032083.031175.3886
ENSG00000144218homo_sapiensENSP0000050041988.662384.584bison_bison_bisonENSBBBP0000002692287.029683.0264
ENSG00000144218homo_sapiensENSP0000050041993.80189.7227monodon_monocerosENSMMNP0001502615192.221388.2117
ENSG00000144218homo_sapiensENSP0000050041993.80190.2936sus_scrofaENSSSCP0000004133491.85388.4185
ENSG00000144218homo_sapiensENSP0000050041996.655894.1272microcebus_murinusENSMICP0000004208594.122391.66
ENSG00000144218homo_sapiensENSP0000050041965.742260.4405octodon_degusENSODEP0000001045484.397977.5916
ENSG00000144218homo_sapiensENSP000005004197.585647.58564octodon_degusENSODEP0000001474477.577.5
ENSG00000144218homo_sapiensENSP0000050041991.843487.7651jaculus_jaculusENSJJAP0000000924493.599389.4431
ENSG00000144218homo_sapiensENSP0000050041962.642758.7276ovis_aries_rambouilletENSOARP0002001522385.049879.7342
ENSG00000144218homo_sapiensENSP0000050041962.561258.7276ursus_maritimusENSUMAP0000001049190.341684.8057
ENSG00000144218homo_sapiensENSP0000050041922.349121.615ursus_maritimusENSUMAP0000001037477.183174.6479
ENSG00000144218homo_sapiensENSP0000050041968.433964.2741ochotona_princepsENSOPRP0000000403966.959362.8891
ENSG00000144218homo_sapiensENSP0000050041987.60283.6052delphinapterus_leucasENSDLEP0000000149390.632986.4979
ENSG00000144218homo_sapiensENSP0000050041992.740688.7439physeter_catodonENSPCTP0000501538091.693687.7419
ENSG00000144218homo_sapiensENSP0000050041992.985388.0914mus_caroliMGP_CAROLIEiJ_P001727292.682987.8049
ENSG00000144218homo_sapiensENSP0000050041992.903888.1729mus_musculusENSMUSP0000015914790.829386.2041
ENSG00000144218homo_sapiensENSP0000050041984.991881.7292dipodomys_ordiiENSDORP0000000683993.452989.8655
ENSG00000144218homo_sapiensENSP0000050041988.743985.6444mustela_putorius_furoENSMPUP0000001199889.400286.2777
ENSG00000144218homo_sapiensENSP0000050041974.632973.9804aotus_nancymaaeENSANAP0000002477298.281497.4221
ENSG00000144218homo_sapiensENSP0000050041997.145296.248saimiri_boliviensis_boliviensisENSSBOP0000002014496.593795.7015
ENSG00000144218homo_sapiensENSP0000050041975.856475.1224chlorocebus_sabaeusENSCSAP0000001322997.484396.5409
ENSG00000144218homo_sapiensENSP0000050041973.817370.9625tupaia_belangeriENSTBEP0000000472573.577270.7317
ENSG00000144218homo_sapiensENSP000005004197.504087.34095mesocricetus_auratusENSMAUP0000001280176.666775
ENSG00000144218homo_sapiensENSP0000050041993.80189.8042phocoena_sinusENSPSNP0000001072792.369588.4337
ENSG00000144218homo_sapiensENSP0000050041976.345871.7781carlito_syrichtaENSTSYP0000003499888.720483.4123
ENSG00000144218homo_sapiensENSP0000050041967.373663.7031panthera_tigris_altaicaENSPTIP0000002172593.438988.3484
ENSG00000144218homo_sapiensENSP0000050041992.985388.0098rattus_norvegicusENSRNOP0000007203789.341784.5611
ENSG00000144218homo_sapiensENSP0000050041996.737494.2904prolemur_simusENSPSMP0000002753194.50292.1116
ENSG00000144218homo_sapiensENSP000005004197.504087.34095microtus_ochrogasterENSMOCP0000000601476.666775
ENSG00000144218homo_sapiensENSP0000050041973.083268.1892microtus_ochrogasterENSMOCP0000000559690.780184.7011
ENSG00000144218homo_sapiensENSP0000050041954.159950.0816sorex_araneusENSSARP0000000123156.223551.9898
ENSG00000144218homo_sapiensENSP0000050041991.92586.7047peromyscus_maniculatus_bairdiiENSPEMP0000001524591.477386.2825
ENSG00000144218homo_sapiensENSP0000050041981.402977.8956bos_mutusENSBMUP0000003541482.615979.0563
ENSG00000144218homo_sapiensENSP0000050041992.577587.8467mus_spicilegusENSMSIP0000002606192.804688.0621
ENSG00000144218homo_sapiensENSP0000050041993.964189.1517cricetulus_griseus_chok1gshdENSCGRP0000101344594.271789.4435
ENSG00000144218homo_sapiensENSP0000050041991.517187.3573pteropus_vampyrusENSPVAP0000000622989.831985.7486
ENSG00000144218homo_sapiensENSP0000050041955.791252.6917myotis_lucifugusENSMLUP0000001390692.682987.5339
ENSG00000144218homo_sapiensENSP0000050041951.87647.0636vombatus_ursinusENSVURP0001000311682.064574.4516
ENSG00000144218homo_sapiensENSP0000050041993.066989.1517rhinolophus_ferrumequinumENSRFEP0001003342791.720387.8617
ENSG00000144218homo_sapiensENSP0000050041995.350792.4144neovison_visonENSNVIP0000002455193.296190.423
ENSG00000144218homo_sapiensENSP0000050041993.637889.3964bos_taurusENSBTAP0000001652393.561589.3236
ENSG00000144218homo_sapiensENSP0000050041962.724359.217heterocephalus_glaber_femaleENSHGLP0000000685686.599181.7568
ENSG00000144218homo_sapiensENSP0000050041924.877723.2463heterocephalus_glaber_femaleENSHGLP0000004949685.915580.2817
ENSG00000144218homo_sapiensENSP0000050041999.347598.6949rhinopithecus_bietiENSRBIP0000001212899.428698.7755
ENSG00000144218homo_sapiensENSP0000050041994.779890.783sciurus_vulgarisENSSVLP0000501697092.442388.5442
ENSG00000144218homo_sapiensENSP0000050041959.543254.2414phascolarctos_cinereusENSPCIP0000001806682.766475.3968
ENSG00000144218homo_sapiensENSP0000050041967.536764.3556procavia_capensisENSPCAP0000001029267.207864.0422
ENSG00000144218homo_sapiensENSP0000050041993.882590.1305nannospalax_galiliENSNGAP0000000264594.112890.3516
ENSG00000144218homo_sapiensENSP0000050041967.047362.969bos_grunniensENSBGRP0000004294890.131684.6491
ENSG00000144218homo_sapiensENSP0000050041976.427473.491chinchilla_lanigeraENSCLAP0000002491093.141289.5626
ENSG00000144218homo_sapiensENSP0000050041991.190987.1126cervus_hanglu_yarkandensisENSCHYP0000001661189.4485.44
ENSG00000144218homo_sapiensENSP0000050041992.495988.1729catagonus_wagneriENSCWAP0000000167790.792686.5492
ENSG00000144218homo_sapiensENSP0000050041994.127290.4568ictidomys_tridecemlineatusENSSTOP0000001089694.667890.9762
ENSG00000144218homo_sapiensENSP0000050041992.659189.8858otolemur_garnettiiENSOGAP0000001189091.909489.1586
ENSG00000144218homo_sapiensENSP0000050041969.16868.2708cebus_imitatorENSCCAP0000001145298.375997.0998
ENSG00000144218homo_sapiensENSP0000050041992.985389.1517moschus_moschiferusENSMMSP0000000241891.492887.7207
ENSG00000144218homo_sapiensENSP0000050041999.347598.7765rhinopithecus_roxellanaENSRROP0000001955797.362196.8026
ENSG00000144218homo_sapiensENSP0000050041992.822287.8467mus_pahariMGP_PahariEiJ_P007262092.89887.9184
ENSG00000144218homo_sapiensENSP0000050041996.900594.1272propithecus_coquereliENSPCOP0000001100195.116192.3939
ENSG00000144218homo_sapiensENSP0000050041936.215321.615drosophila_melanogasterFBpp007731826.539215.8398
ENSG00000144218homo_sapiensENSP0000050041933.686819.8206ciona_intestinalisENSCINP0000001231238.099622.417
ENSG00000144218homo_sapiensENSP000005004195036.2969petromyzon_marinusENSPMAP0000000860549.877936.2083
ENSG00000144218homo_sapiensENSP0000050041948.939635.5628eptatretus_burgeriENSEBUP0000001945045.48933.0553
ENSG00000144218homo_sapiensENSP0000050041944.616634.4209callorhinchus_miliiENSCMIP0000000033564.277349.5887
ENSG00000144218homo_sapiensENSP0000050041915.41611.6639callorhinchus_miliiENSCMIP0000000028754.466941.2104
ENSG00000144218homo_sapiensENSP0000050041915.579112.7243latimeria_chalumnaeENSLACP0000000430357.878847.2727
ENSG00000144218homo_sapiensENSP0000050041948.042439.2333latimeria_chalumnaeENSLACP0000001057475.609861.7458
ENSG00000144218homo_sapiensENSP0000050041951.060439.3964xenopus_tropicalisENSXETP0000006340665.208350.3125
ENSG00000144218homo_sapiensENSP0000050041980.750470.7993chrysemys_picta_belliiENSCPBP0000000941179.838770
ENSG00000144218homo_sapiensENSP0000050041950.978844.2088sphenodon_punctatusENSSPUP0000001276177.255966.9963
ENSG00000144218homo_sapiensENSP0000050041951.631345.5954crocodylus_porosusENSCPRP0000501748479.622670.3145
ENSG00000144218homo_sapiensENSP0000050041920.065317.2104crocodylus_porosusENSCPRP0000501752568.715158.9385
ENSG00000144218homo_sapiensENSP0000050041944.371936.7863laticauda_laticaudataENSLLTP0000000253472.05359.7351
ENSG00000144218homo_sapiensENSP0000050041962.153351.7129notechis_scutatusENSNSUP0000000279472.779460.554
ENSG00000144218homo_sapiensENSP0000050041963.132152.2839pseudonaja_textilisENSPTXP0000000279972.268959.8506
ENSG00000144218homo_sapiensENSP0000050041951.468245.2692anas_platyrhynchos_platyrhynchosENSAPLP0000002746474.322765.371
ENSG00000144218homo_sapiensENSP0000050041920.636218.4339anas_platyrhynchos_platyrhynchosENSAPLP0000001596772.910765.1297
ENSG00000144218homo_sapiensENSP0000050041974.469866.3948gallus_gallusENSGALP0001002210573.688565.6981
ENSG00000144218homo_sapiensENSP0000050041919.331218.5971meleagris_gallopavoENSMGAP0000001567494.891.2
ENSG00000144218homo_sapiensENSP0000050041919.331217.2104meleagris_gallopavoENSMGAP0000001567881.164472.2603
ENSG00000144218homo_sapiensENSP0000050041973.001665.3344serinus_canariaENSSCAP0000002344176.235168.2283
ENSG00000144218homo_sapiensENSP0000050041973.980465.9054parus_majorENSPMJP0000002042975.457667.2213
ENSG00000144218homo_sapiensENSP0000050041952.283943.3116anolis_carolinensisENSACAP0000002431375.234762.3239
ENSG00000144218homo_sapiensENSP0000050041962.805952.2839naja_najaENSNNAP0000002717673.05560.8159
ENSG00000144218homo_sapiensENSP0000050041968.352457.6672podarcis_muralisENSPMRP0000000853676.669764.6844
ENSG00000144218homo_sapiensENSP0000050041916.802614.1925podarcis_muralisENSPMRP0000003371266.237955.9486
ENSG00000144218homo_sapiensENSP0000050041963.866257.1778geospiza_fortisENSGFOP0000001263668.384361.2227
ENSG00000144218homo_sapiensENSP0000050041973.083265.2529taeniopygia_guttataENSTGUP0000002536568.553961.2089
ENSG00000144218homo_sapiensENSP0000050041950.163142.4144salvator_merianaeENSSMRP0000002795278.443966.3265
ENSG00000144218homo_sapiensENSP0000050041972.430763.4584pelodiscus_sinensisENSPSIP0000000706076.683967.1848
ENSG00000144218homo_sapiensENSP0000050041915.334413.2137pelodiscus_sinensisENSPSIP0000000025869.888560.223
ENSG00000144218homo_sapiensENSP0000050041919.331216.5579gopherus_evgoodeiENSGEVP0000502799870.958160.7784
ENSG00000144218homo_sapiensENSP0000050041956.280648.9396gopherus_evgoodeiENSGEVP0000502801875.657965.7895
ENSG00000144218homo_sapiensENSP0000050041918.678615.9869chelonoidis_abingdoniiENSCABP0000000502266.959157.3099
ENSG00000144218homo_sapiensENSP0000050041956.362249.1843chelonoidis_abingdoniiENSCABP0000000501778.433668.4449
ENSG00000144218homo_sapiensENSP0000050041959.787953.9152struthio_camelus_australisENSSCUP0000000407381.991173.9374
ENSG00000144218homo_sapiensENSP0000050041951.386645.2692anser_brachyrhynchusENSABRP0000001029176.08767.029
ENSG00000144218homo_sapiensENSP0000050041973.572665.4976strigops_habroptilaENSSHBP0000501655775.989967.6495
ENSG00000144218homo_sapiensENSP0000050041976.345867.0473terrapene_carolina_triunguisENSTMTP0000000819280.412470.6186
ENSG00000144218homo_sapiensENSP000005004198.972276.36215hucho_huchoENSHHUP0000002534167.073247.561
ENSG00000144218homo_sapiensENSP0000050041973.817365.9869aquila_chrysaetos_chrysaetosENSACCP0002002167678.084669.8016
ENSG00000144218homo_sapiensENSP0000050041969.657462.5612ficedula_albicollisENSFALP0000000403776.867769.0369
ENSG00000144218homo_sapiensENSP0000050041972.838563.9478coturnix_japonicaENSCJPP0000500117072.483863.6364
ENSG00000144218homo_sapiensENSP0000050041958.727644.7798leptobrachium_leishanenseENSLLEP0000002398162.445847.6149

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003690enables double-stranded DNA binding1IEAHomo_sapiens(9606)Function
GO:0003700enables DNA-binding transcription factor activity1IEAHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0006355involved_in regulation of DNA-templated transcription1IEAHomo_sapiens(9606)Process
GO:0010468involved_in regulation of gene expression1IBAHomo_sapiens(9606)Process
GO:0016604located_in nuclear body1IDAHomo_sapiens(9606)Component
GO:0032783part_of super elongation complex1IBAHomo_sapiens(9606)Component
GO:0034612involved_in response to tumor necrosis factor1IMPHomo_sapiens(9606)Process
GO:0035116involved_in embryonic hindlimb morphogenesis1IMPHomo_sapiens(9606)Process

Expression