Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions TF
Localizations Stress granucle
BulkPerturb-seq DataSet_01_130

Description

Ensembl ID ENSG00000143379 Gene ID 9869 Accession 10761
Symbol SETDB1 Alias ESET;KG1T;KMT1E;TDRD21;H3-K9-HMTase4 Full Name SET domain bifurcated histone lysine methyltransferase 1
Status Confidence Length 38482 bases Strand Plus strand
Position 1 : 150926263 - 150964744 RNA binding domain MBD
Summary This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000432348 MBD PF01429 5.9e-12 1
ENSP00000271640 MBD PF01429 6e-12 1
ENSP00000357965 MBD PF01429 6e-12 1
ENSP00000508664 MBD PF01429 6e-12 1
ENSP00000509425 MBD PF01429 6e-12 1
ENSP00000436148 MBD PF01429 0.00025 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
37559904 The cytoplasmic fraction of the histone lysine methyltransferase Setdb1 is essential for embryonic stem cells. Roberta Rapone 2023-08-18 iScience
34794168 Genome surveillance by HUSH-mediated silencing of intronless mobile elements. Marta Seczynska 2022-01-01 Nature
31405032 SETDB-1: A Potential Epigenetic Regulator in Breast Cancer Metastasis. Jacob Batham 2019-08-09 Cancers

Transcripts

Name Transcript ID bp Protein Translation ID
SETDB1-214 ENST00000525956 587 163aa ENSP00000435922
SETDB1-211 ENST00000487584 558 No protein -
SETDB1-209 ENST00000463774 570 No protein -
SETDB1-219 ENST00000692314 4295 1292aa ENSP00000508664
SETDB1-218 ENST00000690229 2984 No protein -
SETDB1-201 ENST00000271640 4437 1291aa ENSP00000271640
SETDB1-207 ENST00000448029 668 156aa ENSP00000409379
SETDB1-202 ENST00000368962 1478 397aa ENSP00000357958
SETDB1-220 ENST00000692827 4418 1292aa ENSP00000509425
SETDB1-217 ENST00000534805 2043 636aa ENSP00000436148
SETDB1-205 ENST00000368969 4370 1290aa ENSP00000357965
SETDB1-203 ENST00000368963 1045 249aa ENSP00000357959
SETDB1-208 ENST00000459773 791 No protein -
SETDB1-213 ENST00000498193 3854 1259aa ENSP00000432348
SETDB1-204 ENST00000368964 548 111aa ENSP00000357960
SETDB1-206 ENST00000423081 590 150aa ENSP00000407831
SETDB1-210 ENST00000481219 623 No protein -
SETDB1-212 ENST00000497314 2321 No protein -
SETDB1-215 ENST00000528749 527 No protein -
SETDB1-216 ENST00000533529 485 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000143379homo_sapiensENSP0000032014724.500713.9814homo_sapiensENSP0000050942514.24158.12694
ENSG00000143379homo_sapiensENSP0000048224049.787830.976homo_sapiensENSP0000050942527.244616.9505
ENSG00000143379homo_sapiensENSP000003867599.438385.57722homo_sapiensENSP0000050942518.730611.0681
ENSG00000143379homo_sapiensENSP000003988377.771644.60405homo_sapiensENSP0000050942516.33139.67492
ENSG00000143379homo_sapiensENSP000004367866.923463.72608homo_sapiensENSP0000050942521.284811.4551
ENSG00000143379homo_sapiensENSP0000031398314.61388.00278homo_sapiensENSP0000050942516.25398.90093
ENSG00000143379homo_sapiensENSP0000047425310.57995.90031homo_sapiensENSP0000050942516.09918.97833
ENSG00000143379homo_sapiensENSP0000026251911.18925.79965homo_sapiensENSP0000050942514.78337.66254
ENSG00000143379homo_sapiensENSP0000041798026.194115.5624homo_sapiensENSP0000050942526.315815.6347
ENSG00000143379homo_sapiensENSP000003010674.515082.49232homo_sapiensENSP0000050942519.349810.6811
ENSG00000143379homo_sapiensENSP0000040465824.49814.7256homo_sapiensENSP0000050942514.16418.51393
ENSG00000143379homo_sapiensENSP000003959299.643925.26706homo_sapiensENSP0000050942520.123810.9907
ENSG00000143379homo_sapiensENSP000004974068.897244.198homo_sapiensENSP0000050942510.99075.18576
ENSG00000143379homo_sapiensENSP0000036468724.793414.4628homo_sapiensENSP0000050942523.219813.5449
ENSG00000143379homo_sapiensENSP000003762048.535764.58839homo_sapiensENSP0000050942519.58210.5263
ENSG00000143379homo_sapiensENSP0000042397214.43228.57143homo_sapiensENSP0000050942515.24779.05573
ENSG00000143379homo_sapiensENSP000002621895.436772.81002homo_sapiensENSP0000050942520.665610.6811
ENSG00000143379homo_sapiensENSP0000034699741.463425.3659homo_sapiensENSP0000050942513.15798.04954
ENSG00000143379homo_sapiensENSP0000036587742.23326.4563homo_sapiensENSP0000050942513.46758.43653

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000143379homo_sapiensENSP0000050942597.755497.2136nomascus_leucogenysENSNLEP0000001220197.378696.8389
ENSG00000143379homo_sapiensENSP0000050942599.845299.7678pan_paniscusENSPPAP0000003658199.845299.7678
ENSG00000143379homo_sapiensENSP0000050942599.690499.6904pongo_abeliiENSPPYP0000000103699.690499.6904
ENSG00000143379homo_sapiensENSP0000050942599.767899.7678pan_troglodytesENSPTRP0000005179899.767899.7678
ENSG00000143379homo_sapiensENSP0000050942599.922699.9226gorilla_gorillaENSGGOP0000001591799.922699.9226
ENSG00000143379homo_sapiensENSP0000050942592.492386.6873sarcophilus_harrisiiENSSHAP0000001488793.578787.7056
ENSG00000143379homo_sapiensENSP0000050942582.430377.0898notamacropus_eugeniiENSMEUP0000000598683.46478.0564
ENSG00000143379homo_sapiensENSP0000050942586.687380.5728notamacropus_eugeniiENSMEUP0000000050589.17282.8822
ENSG00000143379homo_sapiensENSP0000050942587.848386.3003choloepus_hoffmanniENSCHOP0000000356789.089587.5196
ENSG00000143379homo_sapiensENSP0000050942597.987696.7492dasypus_novemcinctusENSDNOP0000000601297.836296.5997
ENSG00000143379homo_sapiensENSP0000050942577.476875.6966erinaceus_europaeusENSEEUP0000001445477.777875.9907
ENSG00000143379homo_sapiensENSP0000050942563.931963.0031echinops_telfairiENSETEP0000001083063.931963.0031
ENSG00000143379homo_sapiensENSP0000050942599.303498.839callithrix_jacchusENSCJAP0000001305798.996998.534
ENSG00000143379homo_sapiensENSP0000050942596.207495.6656cercocebus_atysENSCATP0000004486397.720197.1698
ENSG00000143379homo_sapiensENSP0000050942599.61399.5356macaca_fascicularisENSMFAP0000005732695.973295.8986
ENSG00000143379homo_sapiensENSP0000050942595.046494.6594macaca_mulattaENSMMUP0000003058394.171893.7883
ENSG00000143379homo_sapiensENSP0000050942599.458299.3034macaca_nemestrinaENSMNEP0000000369999.535299.3803
ENSG00000143379homo_sapiensENSP0000050942599.535699.3808papio_anubisENSPANP0000000398299.612799.4578
ENSG00000143379homo_sapiensENSP0000050942599.535699.3808mandrillus_leucophaeusENSMLEP0000001771099.612799.4578
ENSG00000143379homo_sapiensENSP0000050942585.139383.7461tursiops_truncatusENSTTRP0000000659385.803484.3994
ENSG00000143379homo_sapiensENSP0000050942597.368496.2074vulpes_vulpesENSVVUP0000001585097.217996.0587
ENSG00000143379homo_sapiensENSP0000050942598.297297.1362equus_asinusENSEASP0000500263897.842896.6872
ENSG00000143379homo_sapiensENSP0000050942597.523296.2848capra_hircusENSCHIP0000000706197.902196.6589
ENSG00000143379homo_sapiensENSP0000050942596.90495.5882loxodonta_africanaENSLAFP0000000334395.791994.4912
ENSG00000143379homo_sapiensENSP0000050942597.368496.13panthera_leoENSPLOP0000002763797.067995.8333
ENSG00000143379homo_sapiensENSP0000050942597.600696.517ailuropoda_melanoleucaENSAMEP0000000124397.299496.2191
ENSG00000143379homo_sapiensENSP0000050942597.755496.3622bos_indicus_hybridENSBIXP0000504362297.90796.5116
ENSG00000143379homo_sapiensENSP0000050942596.981494.8142oryctolagus_cuniculusENSOCUP0000001100296.981494.8142
ENSG00000143379homo_sapiensENSP0000050942598.297297.2136equus_caballusENSECAP0000003247397.842896.7643
ENSG00000143379homo_sapiensENSP0000050942597.523296.4396canis_lupus_familiarisENSCAFP0084502790397.372596.2906
ENSG00000143379homo_sapiensENSP0000050942597.368496.13panthera_pardusENSPPRP0000001159897.519496.2791
ENSG00000143379homo_sapiensENSP0000050942597.29195.743marmota_marmota_marmotaENSMMMP0000002179196.841395.3005
ENSG00000143379homo_sapiensENSP0000050942597.755496.6718balaenoptera_musculusENSBMSP0001002150797.755496.6718
ENSG00000143379homo_sapiensENSP0000050942596.981495.356cavia_porcellusENSCPOP0000000147297.131895.5039
ENSG00000143379homo_sapiensENSP0000050942597.445896.13felis_catusENSFCAP0000000895697.596996.2791
ENSG00000143379homo_sapiensENSP0000050942597.445896.2074ursus_americanusENSUAMP0000003519096.920795.689
ENSG00000143379homo_sapiensENSP0000050942592.414987.4613monodelphis_domesticaENSMODP0000002347484.084579.5775
ENSG00000143379homo_sapiensENSP0000050942597.600696.3622bison_bison_bisonENSBBBP0000001630197.827896.5865
ENSG00000143379homo_sapiensENSP0000050942597.600696.517monodon_monocerosENSMMNP0001500568597.600696.517
ENSG00000143379homo_sapiensENSP0000050942597.29195.743sus_scrofaENSSSCP0000000708697.29195.743
ENSG00000143379homo_sapiensENSP0000050942597.910297.0588microcebus_murinusENSMICP0000000039996.934996.092
ENSG00000143379homo_sapiensENSP0000050942596.826695.5108octodon_degusENSODEP0000001691797.278495.9565
ENSG00000143379homo_sapiensENSP0000050942597.368496.2074ovis_aries_rambouilletENSOARP0002001407197.746796.5812
ENSG00000143379homo_sapiensENSP0000050942595.897894.7368ursus_maritimusENSUMAP0000000414594.43693.2927
ENSG00000143379homo_sapiensENSP0000050942592.724589.9381ochotona_princepsENSOPRP0000001403296.224993.3333
ENSG00000143379homo_sapiensENSP0000050942597.600696.6718delphinapterus_leucasENSDLEP0000001212297.525196.5971
ENSG00000143379homo_sapiensENSP0000050942595.433492.2601mus_caroliMGP_CAROLIEiJ_P005916794.482891.341
ENSG00000143379homo_sapiensENSP0000050942595.278692.1827mus_musculusENSMUSP0000001584194.113291.055
ENSG00000143379homo_sapiensENSP0000050942595.201293.1115dipodomys_ordiiENSDORP0000000639895.571193.4732
ENSG00000143379homo_sapiensENSP0000050942594.349892.2601mustela_putorius_furoENSMPUP0000000426493.4191.341
ENSG00000143379homo_sapiensENSP0000050942599.303499.0712aotus_nancymaaeENSANAP0000000053698.768398.5373
ENSG00000143379homo_sapiensENSP0000050942598.606898.452saimiri_boliviensis_boliviensisENSSBOP0000002436098.075497.9215
ENSG00000143379homo_sapiensENSP0000050942573.06572.291vicugna_pacosENSVPAP0000000505577.124276.3072
ENSG00000143379homo_sapiensENSP0000050942587.770987.6935chlorocebus_sabaeusENSCSAP0000001405199.56199.4732
ENSG00000143379homo_sapiensENSP0000050942590.247789.3189tupaia_belangeriENSTBEP0000000806797.328996.3272
ENSG00000143379homo_sapiensENSP0000050942584.055781.7337mesocricetus_auratusENSMAUP0000002459895.851793.2039
ENSG00000143379homo_sapiensENSP0000050942597.368496.3622phocoena_sinusENSPSNP0000000361397.142996.139
ENSG00000143379homo_sapiensENSP0000050942597.523296.3622camelus_dromedariusENSCDRP0000502613997.222296.0648
ENSG00000143379homo_sapiensENSP0000050942578.48377.0124carlito_syrichtaENSTSYP0000001160197.782195.9499
ENSG00000143379homo_sapiensENSP0000050942596.671895.4334panthera_tigris_altaicaENSPTIP0000001502497.047495.8042
ENSG00000143379homo_sapiensENSP0000050942595.046491.7183rattus_norvegicusENSRNOP0000002870992.889689.6369
ENSG00000143379homo_sapiensENSP0000050942598.374697.4458prolemur_simusENSPSMP0000003171897.171396.2538
ENSG00000143379homo_sapiensENSP0000050942595.046492.7245microtus_ochrogasterENSMOCP0000001942695.193892.8682
ENSG00000143379homo_sapiensENSP0000050942564.705962.3839sorex_araneusENSSARP0000000247865.007862.675
ENSG00000143379homo_sapiensENSP0000050942588.467586.3003peromyscus_maniculatus_bairdiiENSPEMP0000000921195.2592.9167
ENSG00000143379homo_sapiensENSP0000050942594.814293.5759bos_mutusENSBMUP0000003213091.554690.3587
ENSG00000143379homo_sapiensENSP0000050942595.433492.3375mus_spicilegusENSMSIP0000000619694.266191.208
ENSG00000143379homo_sapiensENSP0000050942595.123892.4923cricetulus_griseus_chok1gshdENSCGRP0000100862595.716593.0685
ENSG00000143379homo_sapiensENSP0000050942587.848386.3777pteropus_vampyrusENSPVAP0000000412487.916386.4446
ENSG00000143379homo_sapiensENSP0000050942596.749294.3498myotis_lucifugusENSMLUP0000000956494.912792.5588
ENSG00000143379homo_sapiensENSP0000050942592.724587.4613vombatus_ursinusENSVURP0001000024293.740288.4194
ENSG00000143379homo_sapiensENSP0000050942592.724587.4613vombatus_ursinusENSVURP0001001939493.740288.4194
ENSG00000143379homo_sapiensENSP0000050942597.600695.5882rhinolophus_ferrumequinumENSRFEP0001003213195.747993.7737
ENSG00000143379homo_sapiensENSP0000050942597.67896.3622neovison_visonENSNVIP0000002060497.301595.9907
ENSG00000143379homo_sapiensENSP0000050942597.755496.3622bos_taurusENSBTAP0000000010797.90796.5116
ENSG00000143379homo_sapiensENSP0000050942596.362295.1238heterocephalus_glaber_femaleENSHGLP0000001551796.287795.0503
ENSG00000143379homo_sapiensENSP0000050942599.458299.3034rhinopithecus_bietiENSRBIP0000003758399.535299.3803
ENSG00000143379homo_sapiensENSP0000050942597.368496.2074canis_lupus_dingoENSCAFP0002001766194.302893.1784
ENSG00000143379homo_sapiensENSP0000050942597.987696.6718sciurus_vulgarisENSSVLP0000500210097.760696.4479
ENSG00000143379homo_sapiensENSP0000050942581.965980.1084procavia_capensisENSPCAP0000000241296.272794.0909
ENSG00000143379homo_sapiensENSP0000050942593.653391.4861nannospalax_galiliENSNGAP0000002076796.955194.7115
ENSG00000143379homo_sapiensENSP0000050942597.445896.0526bos_grunniensENSBGRP0000000221897.521396.127
ENSG00000143379homo_sapiensENSP0000050942597.368495.8204chinchilla_lanigeraENSCLAP0000000027296.843795.3041
ENSG00000143379homo_sapiensENSP0000050942597.832896.7492cervus_hanglu_yarkandensisENSCHYP0000001364497.984596.8992
ENSG00000143379homo_sapiensENSP0000050942597.368495.9752catagonus_wagneriENSCWAP0000000946697.293195.901
ENSG00000143379homo_sapiensENSP0000050942597.910296.2848ictidomys_tridecemlineatusENSSTOP0000000606596.051694.4571
ENSG00000143379homo_sapiensENSP0000050942592.414990.4025otolemur_garnettiiENSOGAP0000000923392.701990.6832
ENSG00000143379homo_sapiensENSP0000050942599.303498.9938cebus_imitatorENSCCAP0000001433399.073498.7645
ENSG00000143379homo_sapiensENSP0000050942594.349892.4923urocitellus_parryiiENSUPAP0001000448494.7992.9238
ENSG00000143379homo_sapiensENSP0000050942597.600696.3622moschus_moschiferusENSMMSP0000002548397.979896.7366
ENSG00000143379homo_sapiensENSP0000050942599.535699.4582rhinopithecus_roxellanaENSRROP0000001703699.535699.4582
ENSG00000143379homo_sapiensENSP0000050942598.219896.904propithecus_coquereliENSPCOP0000003030098.219896.904
ENSG00000143379homo_sapiensENSP000005094258.513936.03715caenorhabditis_elegansK09F5.5.128.277620.0514
ENSG00000143379homo_sapiensENSP000005094258.746135.88235caenorhabditis_elegansF34D6.4.140.647527.3381
ENSG00000143379homo_sapiensENSP000005094259.752325.34056caenorhabditis_elegansK12H6.11.131.343317.1642
ENSG00000143379homo_sapiensENSP0000050942511.84216.73375caenorhabditis_elegansW01C8.3.116.05469.12907
ENSG00000143379homo_sapiensENSP0000050942514.31898.04954caenorhabditis_elegansC43E11.3a.111.53376.48379
ENSG00000143379homo_sapiensENSP000005094259.055734.95356caenorhabditis_elegansF02D10.7.128.746915.7248
ENSG00000143379homo_sapiensENSP0000050942518.188911.3003caenorhabditis_elegansR05D3.11.118.021511.1963
ENSG00000143379homo_sapiensENSP0000050942512.69357.19814caenorhabditis_elegansT12D8.1.16.626263.75758
ENSG00000143379homo_sapiensENSP0000050942510.52635.95975caenorhabditis_elegansR11E3.4.222.258612.6023
ENSG00000143379homo_sapiensENSP0000050942510.99076.57895caenorhabditis_elegansC49F5.2.120.056512.0056
ENSG00000143379homo_sapiensENSP000005094259.520125.18576caenorhabditis_elegansC41G7.4.123.791112.9594
ENSG00000143379homo_sapiensENSP000005094259.597525.03096caenorhabditis_elegansY24D9A.2.121.83111.4437
ENSG00000143379homo_sapiensENSP0000050942519.504611.0681drosophila_melanogasterFBpp007361010.66896.05419
ENSG00000143379homo_sapiensENSP0000050942512.61616.88855drosophila_melanogasterFBpp02971527.322553.9982
ENSG00000143379homo_sapiensENSP0000050942541.563528.7152drosophila_melanogasterFBpp011168942.551529.3978
ENSG00000143379homo_sapiensENSP0000050942512.07436.34675drosophila_melanogasterFBpp00703476.417113.3731
ENSG00000143379homo_sapiensENSP0000050942521.439610.9907drosophila_melanogasterFBpp030520716.7178.5697
ENSG00000143379homo_sapiensENSP000005094259.133135.88235drosophila_melanogasterFBpp011212843.866228.2528
ENSG00000143379homo_sapiensENSP0000050942534.752325.5418ciona_intestinalisENSCINP0000001948548.17635.4077
ENSG00000143379homo_sapiensENSP000005094259.597525.49536ciona_intestinalisENSCINP0000000315621.052612.0543
ENSG00000143379homo_sapiensENSP0000050942562.229149.1486petromyzon_marinusENSPMAP0000000174866.391452.436
ENSG00000143379homo_sapiensENSP0000050942542.260134.8297eptatretus_burgeriENSEBUP0000000886256.115146.2487
ENSG00000143379homo_sapiensENSP0000050942579.876271.3622latimeria_chalumnaeENSLACP0000001266678.658570.2744
ENSG00000143379homo_sapiensENSP0000050942510.21679.36532lepisosteus_oculatusENSLOCP0000000792489.189281.7568
ENSG00000143379homo_sapiensENSP0000050942544.891632.5077clupea_harengusENSCHAP0000003013863.043545.6522
ENSG00000143379homo_sapiensENSP0000050942567.182756.4241clupea_harengusENSCHAP0000001151167.706756.8643
ENSG00000143379homo_sapiensENSP0000050942548.606834.3653danio_rerioENSDARP0000008276943.732630.9192
ENSG00000143379homo_sapiensENSP0000050942566.718355.6502danio_rerioENSDARP0000013650571.004959.2257
ENSG00000143379homo_sapiensENSP0000050942567.337556.3467carassius_auratusENSCARP0000008728370.161358.7097
ENSG00000143379homo_sapiensENSP0000050942549.535634.3653carassius_auratusENSCARP0000005320340.20127.8894
ENSG00000143379homo_sapiensENSP0000050942566.873156.0372carassius_auratusENSCARP0000004428670.07358.7186
ENSG00000143379homo_sapiensENSP0000050942549.845234.7523carassius_auratusENSCARP0000003699341.045228.617
ENSG00000143379homo_sapiensENSP0000050942566.640955.805carassius_auratusENSCARP0000011726670.98159.4394
ENSG00000143379homo_sapiensENSP0000050942560.216750.0774astyanax_mexicanusENSAMXP0000001665769.464357.7679
ENSG00000143379homo_sapiensENSP0000050942551.780236.3777astyanax_mexicanusENSAMXP0000001030440.374228.3645
ENSG00000143379homo_sapiensENSP0000050942552.167236.0681ictalurus_punctatusENSIPUP0000001162347.531732.8632
ENSG00000143379homo_sapiensENSP0000050942566.331355.9598ictalurus_punctatusENSIPUP0000000664569.505358.6375
ENSG00000143379homo_sapiensENSP0000050942533.281723.9938esox_luciusENSELUP0000000514259.972143.2357
ENSG00000143379homo_sapiensENSP0000050942568.266357.6625esox_luciusENSELUP0000004813568.745158.067
ENSG00000143379homo_sapiensENSP0000050942566.021754.8762electrophorus_electricusENSEEEP0000002545470.437758.5467
ENSG00000143379homo_sapiensENSP0000050942545.278632.8947electrophorus_electricusENSEEEP0000001367960.371543.8596
ENSG00000143379homo_sapiensENSP0000050942567.260157.0433oncorhynchus_kisutchENSOKIP0000509174068.85958.3994
ENSG00000143379homo_sapiensENSP0000050942566.873156.9659oncorhynchus_kisutchENSOKIP0000500331568.789858.5987
ENSG00000143379homo_sapiensENSP0000050942545.433433.5913oncorhynchus_kisutchENSOKIP0000506447157.380342.4242
ENSG00000143379homo_sapiensENSP0000050942567.414957.2755oncorhynchus_mykissENSOMYP0000012443664.280454.6125
ENSG00000143379homo_sapiensENSP0000050942522.987615.2477oncorhynchus_mykissENSOMYP0000011237242.307728.0627
ENSG00000143379homo_sapiensENSP0000050942545.665633.7461oncorhynchus_mykissENSOMYP0000009379757.448942.4538
ENSG00000143379homo_sapiensENSP0000050942567.105357.0433oncorhynchus_mykissENSOMYP0000001080268.75558.4457
ENSG00000143379homo_sapiensENSP0000050942567.337556.9659salmo_salarENSSSAP0000005044068.774758.1818
ENSG00000143379homo_sapiensENSP0000050942567.260156.8885salmo_salarENSSSAP0000015219468.804458.1948
ENSG00000143379homo_sapiensENSP0000050942542.724530.418salmo_salarENSSSAP0000006066350.090735.6624
ENSG00000143379homo_sapiensENSP0000050942543.343731.8885salmo_truttaENSSTUP0000008579653.282639.2008
ENSG00000143379homo_sapiensENSP0000050942566.950556.8111salmo_truttaENSSTUP0000000080368.705358.3002
ENSG00000143379homo_sapiensENSP0000050942566.950556.8111salmo_truttaENSSTUP0000008237868.979358.5327
ENSG00000143379homo_sapiensENSP0000050942565.634754.7214gadus_morhuaENSGMOP0000000640867.677656.4246
ENSG00000143379homo_sapiensENSP0000050942566.873156.5015fundulus_heteroclitusENSFHEP0000002027068.408657.7989
ENSG00000143379homo_sapiensENSP0000050942567.105356.7337poecilia_reticulataENSPREP0000002586268.75558.1285
ENSG00000143379homo_sapiensENSP0000050942566.873156.5789xiphophorus_maculatusENSXMAP0000001664368.954558.34
ENSG00000143379homo_sapiensENSP0000050942567.414956.8885oryzias_latipesENSORLP0000001329570.355459.37
ENSG00000143379homo_sapiensENSP0000050942564.705955.1084cyclopterus_lumpusENSCLMP0000502036569.205358.9404
ENSG00000143379homo_sapiensENSP0000050942567.027956.8111oreochromis_niloticusENSONIP0000000813670.406559.6748
ENSG00000143379homo_sapiensENSP0000050942566.873156.6563haplochromis_burtoniENSHBUP0000002369170.301159.5606
ENSG00000143379homo_sapiensENSP0000050942566.873156.6563astatotilapia_callipteraENSACLP0000003026970.301159.5606
ENSG00000143379homo_sapiensENSP0000050942567.105356.5789sparus_aurataENSSAUP0001004236868.483457.7409
ENSG00000143379homo_sapiensENSP0000050942567.569757.2755lates_calcariferENSLCAP0001005286769.285758.7302
ENSG00000143379homo_sapiensENSP0000050942576.470667.5697xenopus_tropicalisENSXETP0000007489377.067168.0967
ENSG00000143379homo_sapiensENSP0000050942586.068179.4118chrysemys_picta_belliiENSCPBP0000001143186.402579.7203
ENSG00000143379homo_sapiensENSP0000050942582.972176.3158sphenodon_punctatusENSSPUP0000000390585.7678.88
ENSG00000143379homo_sapiensENSP0000050942580.80573.6068crocodylus_porosusENSCPRP0000501047584.05876.57
ENSG00000143379homo_sapiensENSP0000050942581.733773.452laticauda_laticaudataENSLLTP0000000063682.953774.5483
ENSG00000143379homo_sapiensENSP0000050942572.755465.0155pseudonaja_textilisENSPTXP0000002049477.239169.0222
ENSG00000143379homo_sapiensENSP0000050942578.405670.9752pseudonaja_textilisENSPTXP0000002047479.952672.3757
ENSG00000143379homo_sapiensENSP0000050942583.978376.935anas_platyrhynchos_platyrhynchosENSAPLP0000001893883.978376.935
ENSG00000143379homo_sapiensENSP0000050942583.204374.8452gallus_gallusENSGALP0001004265077.617369.8195
ENSG00000143379homo_sapiensENSP0000050942576.083667.5697meleagris_gallopavoENSMGAP0000000040780.706171.6749
ENSG00000143379homo_sapiensENSP0000050942581.346772.8328serinus_canariaENSSCAP0000001641481.789973.2296
ENSG00000143379homo_sapiensENSP0000050942566.795758.7461anolis_carolinensisENSACAP0000001172679.759770.1479
ENSG00000143379homo_sapiensENSP0000050942563.544954.5666neolamprologus_brichardiENSNBRP0000000414071.828561.6798
ENSG00000143379homo_sapiensENSP0000050942569.272460.6037naja_najaENSNNAP0000000809375.847566.3559
ENSG00000143379homo_sapiensENSP0000050942582.198173.9164podarcis_muralisENSPMRP0000003239384.892176.3389
ENSG00000143379homo_sapiensENSP0000050942576.083668.7307geospiza_fortisENSGFOP0000001106083.446575.382
ENSG00000143379homo_sapiensENSP0000050942581.965973.2198taeniopygia_guttataENSTGUP0000003370881.27472.6017
ENSG00000143379homo_sapiensENSP0000050942566.099158.9009erpetoichthys_calabaricusENSECRP0000001139874.067666.0017
ENSG00000143379homo_sapiensENSP0000050942566.563556.192kryptolebias_marmoratusENSKMAP0000000151267.876957.3007
ENSG00000143379homo_sapiensENSP0000050942583.204373.839salvator_merianaeENSSMRP0000002753484.980275.415
ENSG00000143379homo_sapiensENSP0000050942566.950556.6563oryzias_javanicusENSOJAP0000004259669.758159.0323
ENSG00000143379homo_sapiensENSP0000050942565.325155.6502amphilophus_citrinellusENSACIP0000000959571.586160.9839
ENSG00000143379homo_sapiensENSP0000050942566.950556.6563dicentrarchus_labraxENSDLAP0000501431670.439759.6091
ENSG00000143379homo_sapiensENSP0000050942562.770953.6378amphiprion_perculaENSAPEP0000001107270.767960.4712
ENSG00000143379homo_sapiensENSP0000050942564.705955.5728oryzias_sinensisENSOSIP0000003729071.636761.5253
ENSG00000143379homo_sapiensENSP0000050942554.179648.065pelodiscus_sinensisENSPSIP0000000921882.644673.3176
ENSG00000143379homo_sapiensENSP0000050942586.377779.5666gopherus_evgoodeiENSGEVP0000502358186.310979.505
ENSG00000143379homo_sapiensENSP0000050942585.758579.1022chelonoidis_abingdoniiENSCABP0000001099987.312880.5359
ENSG00000143379homo_sapiensENSP0000050942567.801957.3529seriola_dumeriliENSSDUP0000001026170.30559.4703
ENSG00000143379homo_sapiensENSP0000050942563.544953.4056cottoperca_gobioENSCGOP0000000552470.291159.0753
ENSG00000143379homo_sapiensENSP0000050942584.442777.6316struthio_camelus_australisENSSCUP0000000613485.30178.4206
ENSG00000143379homo_sapiensENSP0000050942581.346774.4582anser_brachyrhynchusENSABRP0000000939783.878776.7757
ENSG00000143379homo_sapiensENSP0000050942566.795755.805gasterosteus_aculeatusENSGACP0000001544968.929757.5879
ENSG00000143379homo_sapiensENSP0000050942563.544953.483cynoglossus_semilaevisENSCSEP0000000471670.959459.7234
ENSG00000143379homo_sapiensENSP0000050942567.182756.4241poecilia_formosaENSPFOP0000000455566.108155.5217
ENSG00000143379homo_sapiensENSP0000050942567.647156.7337poecilia_formosaENSPFOP0000002364164.501854.0959
ENSG00000143379homo_sapiensENSP0000050942566.795756.192myripristis_murdjanENSMMDP0000501357470.391559.217
ENSG00000143379homo_sapiensENSP0000050942563.080553.4056sander_luciopercaENSSLUP0000002522970.80859.9479
ENSG00000143379homo_sapiensENSP0000050942582.817375.387strigops_habroptilaENSSHBP0000501924583.010175.5625
ENSG00000143379homo_sapiensENSP0000050942563.157953.87amphiprion_ocellarisENSAOCP0000002096771.83161.2676
ENSG00000143379homo_sapiensENSP0000050942576.857671.517terrapene_carolina_triunguisENSTMTP0000001008486.952780.9107
ENSG00000143379homo_sapiensENSP0000050942531.114623.9164hucho_huchoENSHHUP0000000003759.643945.8457
ENSG00000143379homo_sapiensENSP0000050942514.241510.0619hucho_huchoENSHHUP0000005649850.688735.8127
ENSG00000143379homo_sapiensENSP000005094258.823537.35294hucho_huchoENSHHUP0000002755267.455656.213
ENSG00000143379homo_sapiensENSP0000050942560.758552.1672hucho_huchoENSHHUP0000008132875.335964.6833
ENSG00000143379homo_sapiensENSP0000050942556.965949.6904hucho_huchoENSHHUP0000007995575.642365.9815
ENSG00000143379homo_sapiensENSP0000050942566.640956.4241betta_splendensENSBSLP0000004728166.899856.6434
ENSG00000143379homo_sapiensENSP0000050942551.16136.0681pygocentrus_nattereriENSPNAP0000001117244.662231.4865
ENSG00000143379homo_sapiensENSP0000050942566.176555.7276pygocentrus_nattereriENSPNAP0000001557170.08259.0164
ENSG00000143379homo_sapiensENSP0000050942567.027956.0372anabas_testudineusENSATEP0000003422369.782458.34
ENSG00000143379homo_sapiensENSP000005094258.900935.88235ciona_savignyiENSCSAVP0000000785314.42919.53576
ENSG00000143379homo_sapiensENSP0000050942520.278615.6347ciona_savignyiENSCSAVP0000000974256.7143.7229
ENSG00000143379homo_sapiensENSP000005094259.210535.10836ciona_savignyiENSCSAVP0000000009621.597111.9782
ENSG00000143379homo_sapiensENSP0000050942567.801957.3529seriola_lalandi_dorsalisENSSLDP0000001939769.96859.1853
ENSG00000143379homo_sapiensENSP0000050942563.467553.7926labrus_bergyltaENSLBEP0000003456169.373958.7986
ENSG00000143379homo_sapiensENSP0000050942563.931954.4118pundamilia_nyerereiENSPNYP000000052407059.5763
ENSG00000143379homo_sapiensENSP0000050942567.182756.5789mastacembelus_armatusENSMAMP0000002254063.173253.2023
ENSG00000143379homo_sapiensENSP0000050942514.705912.7709stegastes_partitusENSSPAP0000001623474.509864.7059
ENSG00000143379homo_sapiensENSP0000050942564.164154.4892oncorhynchus_tshawytschaENSOTSP0000507547171.036860.3256
ENSG00000143379homo_sapiensENSP0000050942564.009354.4118oncorhynchus_tshawytschaENSOTSP0000503150471.47860.7606
ENSG00000143379homo_sapiensENSP0000050942545.665633.6687oncorhynchus_tshawytschaENSOTSP0000502130058.531743.1548
ENSG00000143379homo_sapiensENSP0000050942567.105356.4241acanthochromis_polyacanthusENSAPOP0000001344169.806858.6957
ENSG00000143379homo_sapiensENSP0000050942584.055776.7028aquila_chrysaetos_chrysaetosENSACCP0002000217884.910177.4824
ENSG00000143379homo_sapiensENSP0000050942565.712154.7988nothobranchius_furzeriENSNFUP0001501951167.595556.3694
ENSG00000143379homo_sapiensENSP0000050942567.492356.8885cyprinodon_variegatusENSCVAP0000002465769.7658.8
ENSG00000143379homo_sapiensENSP0000050942565.634756.192denticeps_clupeoidesENSDCDP0000000687770.431960.299
ENSG00000143379homo_sapiensENSP0000050942548.606831.8885denticeps_clupeoidesENSDCDP0000003630459.923739.313
ENSG00000143379homo_sapiensENSP0000050942515.325111.7647denticeps_clupeoidesENSDCDP0000005232866.44351.0067
ENSG00000143379homo_sapiensENSP0000050942567.724556.8885larimichthys_croceaENSLCRP0000501420370.281159.0361
ENSG00000143379homo_sapiensENSP0000050942563.699753.1734takifugu_rubripesENSTRUP0000005869165.787454.9161
ENSG00000143379homo_sapiensENSP0000050942566.486154.9536hippocampus_comesENSHCOP0000002487570.757858.4843
ENSG00000143379homo_sapiensENSP0000050942567.260156.6563cyprinus_carpio_carpioENSCCRP0000016546871.522660.2469
ENSG00000143379homo_sapiensENSP0000050942550.619235.2167cyprinus_carpio_carpioENSCCRP0000016411241.15828.6344
ENSG00000143379homo_sapiensENSP0000050942566.795755.7276cyprinus_carpio_carpioENSCCRP0000000591571.204659.4059
ENSG00000143379homo_sapiensENSP0000050942549.22634.6749cyprinus_carpio_carpioENSCCRP0000009039242.315429.8071
ENSG00000143379homo_sapiensENSP0000050942582.972174.4582coturnix_japonicaENSCJPP0000501878474.54866.8985
ENSG00000143379homo_sapiensENSP0000050942566.795756.7337poecilia_latipinnaENSPLAP0000001520569.095358.687
ENSG00000143379homo_sapiensENSP0000050942564.241554.1022poecilia_latipinnaENSPLAP0000001359368.200557.4363
ENSG00000143379homo_sapiensENSP0000050942567.027955.9598sinocyclocheilus_grahamiENSSGRP0000002591269.670258.1657
ENSG00000143379homo_sapiensENSP0000050942549.380834.9071sinocyclocheilus_grahamiENSSGRP0000011056039.850128.1699
ENSG00000143379homo_sapiensENSP0000050942547.445833.6687sinocyclocheilus_grahamiENSSGRP0000005932243.536930.8949
ENSG00000143379homo_sapiensENSP0000050942566.795755.8824sinocyclocheilus_grahamiENSSGRP0000001405971.087359.4728
ENSG00000143379homo_sapiensENSP0000050942566.873156.6563maylandia_zebraENSMZEP0000502144270.301159.5606
ENSG00000143379homo_sapiensENSP0000050942565.789555.3406tetraodon_nigroviridisENSTNIP000000108896857.2
ENSG00000143379homo_sapiensENSP0000050942568.034158.0495paramormyrops_kingsleyaeENSPKIP0000002990869.761959.5238
ENSG00000143379homo_sapiensENSP0000050942568.111558.9783scleropages_formosusENSSFOP0001503483269.236859.9528
ENSG00000143379homo_sapiensENSP0000050942576.470667.8793leptobrachium_leishanenseENSLLEP0000003889365.517258.1565
ENSG00000143379homo_sapiensENSP0000050942566.873156.1146scophthalmus_maximusENSSMAP0000002516767.552856.6849
ENSG00000143379homo_sapiensENSP0000050942566.873156.7337oryzias_melastigmaENSOMEP0000000824969.621359.0653

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003677enables DNA binding1IEAHomo_sapiens(9606)Function
GO:0003682enables chromatin binding1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus2IBA,IMPHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005694located_in chromosome1IEAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IMPHomo_sapiens(9606)Component
GO:0008270enables zinc ion binding1IEAHomo_sapiens(9606)Function
GO:0010629involved_in negative regulation of gene expression1IBAHomo_sapiens(9606)Process
GO:0043231located_in intracellular membrane-bounded organelle1IDAHomo_sapiens(9606)Component
GO:0045869involved_in negative regulation of single stranded viral RNA replication via double stranded DNA intermediate1ISSHomo_sapiens(9606)Process
GO:0046974enables histone H3K9 methyltransferase activity2IBA,IDAHomo_sapiens(9606)Function
GO:0051567involved_in histone H3-K9 methylation1IBAHomo_sapiens(9606)Process
GO:0070828involved_in heterochromatin organization1IBAHomo_sapiens(9606)Process
GO:0090309involved_in positive regulation of DNA methylation-dependent heterochromatin formation3IBA,IMP,ISSHomo_sapiens(9606)Process
GO:0140947enables histone H3K9me2 methyltransferase activity1IEAHomo_sapiens(9606)Function
GO:0140948enables histone H3K9 monomethyltransferase activity1IEAHomo_sapiens(9606)Function
GO:0140949enables histone H3K9 trimethyltransferase activity1IDAHomo_sapiens(9606)Function
GO:1990841enables promoter-specific chromatin binding1IDAHomo_sapiens(9606)Function

Expression