Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs diverse
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq DataSet_01_241 DataSet_01_375

Description

Ensembl ID ENSG00000138035 Gene ID 87178 Accession 23166
Symbol PNPT1 Alias OLD35;SCA25;DFNB70;PNPASE;old-35;COXPD13 Full Name polyribonucleotide nucleotidyltransferase 1
Status Confidence Length 59803 bases Strand Minus strand
Position 2 : 55634061 - 55693863 RNA binding domain RNase_PH , RNase_PH_C , PNPase , KH_1
Summary The protein encoded by this gene belongs to the evolutionary conserved polynucleotide phosphorylase family comprised of phosphate dependent 3'-to-5' exoribonucleases implicated in RNA processing and degradation. This enzyme is predominantly localized in the mitochondrial intermembrane space and is involved in import of RNA to mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency-13 and autosomal recessive nonsyndromic deafness-70. Related pseudogenes are found on chromosomes 3 and 7. [provided by RefSeq, Dec 2012]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000393953 RNase_PH_C PF03725 1e-16 1
ENSP00000393953 KH_1 PF00013 1.9e-07 2
ENSP00000393953 PNPase PF03726 2.7e-07 3
ENSP00000393953 RNase_PH PF01138 3.7e-39 4
ENSP00000393953 RNase_PH PF01138 3.7e-39 5
ENSP00000400646 RNase_PH_C PF03725 1e-16 1
ENSP00000400646 KH_1 PF00013 1.9e-07 2
ENSP00000400646 PNPase PF03726 2.7e-07 3
ENSP00000400646 RNase_PH PF01138 3.7e-39 4
ENSP00000400646 RNase_PH PF01138 3.7e-39 5
ENSP00000260604 RNase_PH PF01138 9.9e-13 1
ENSP00000411057 RNase_PH PF01138 6.4e-07 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
32574647 Regulation of cellular senescence by eukaryotic members of the FAH superfamily - A role in calcium homeostasis? H K Alexander Weiss 2020-09-01 Mechanisms of ageing and development
32809827 A Novel Redox Modulator Induces a GPX4-Mediated Cell Death That Is Dependent on Iron and Reactive Oxygen Species. Shuai Hu 2020-09-10 Journal of medicinal chemistry
32221480 Analysis of mitochondrial m1A/G RNA modification reveals links to nuclear genetic variants and associated disease processes. Tasnim Aminah Ali 2020-03-27 Communications biology
33199448 Heterogeneity of PNPT1 neuroimaging: mitochondriopathy, interferonopathy or both? Alessandra Pennisi 2022-02-01 Journal of medical genetics
36266447 8-Oxoguanine: from oxidative damage to epigenetic and epitranscriptional modification. Young Ja Hahm 2022-10-01 Experimental & molecular medicine
28645153 Defective mitochondrial RNA processing due to PNPT1 variants causes Leigh syndrome. Sanna Matilainen 2017-09-01 Human molecular genetics
34074335 Circ-PNPT1 contributes to gestational diabetes mellitus (GDM) by regulating the function of trophoblast cells through miR-889-3p/PAK1 axis. Li Zhang 2021-06-01 Diabetology & metabolic syndrome

Transcripts

Name Transcript ID bp Protein Translation ID
PNPT1-205 ENST00000447944 4549 783aa ENSP00000400646
PNPT1-202 ENST00000415374 3308 783aa ENSP00000393953
PNPT1-201 ENST00000260604 3596 179aa ENSP00000260604
PNPT1-206 ENST00000481066 1281 No protein -
PNPT1-203 ENST00000415489 555 139aa ENSP00000411057
PNPT1-204 ENST00000429805 583 71aa ENSP00000411994
PNPT1-207 ENST00000625249 216 71aa ENSP00000486227

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
15318Heart Failure2.9347593E-004-
17450Blood Pressure5.821e-00619060910
17451Blood Pressure2.677e-00519060910
17452Blood Pressure9.378e-00619060910
17467Blood Pressure1.4e-00519060910
25161Body Weight2.6980000E-005-
25177Body Weight2.1730000E-005-
25178Body Weight7.5780000E-005-
25199Body Weight5.4190000E-005-
28431Nutritional and Metabolic Diseases2.6640000E-005-
29438Cholesterol, LDL4.9860000E-005-
41205Platelet Function Tests5.8360505E-006-
46913Platelet Function Tests7.2638000E-006-
48255Child Development Disorders, Pervasive4.7078500E-005-
58650Respiratory Function Tests2.1665000E-00821946350
58651Respiratory Function Tests2.2117000E-00821946350
58652Respiratory Function Tests1.7882000E-00821946350
58654Respiratory Function Tests2.1456000E-00821946350
58655Respiratory Function Tests2.0981000E-00821946350
74877Body Height4E-820881960
81379Amyotrophic Lateral Sclerosis1E-619451621
87171Immunoglobulins5E-623382691
98017Body Height1E-2525429064
1016233-hydroxy-1-methylpropylmercapturic acid4E-726053186
101624Smoking4E-726053186
103850Hernia, Inguinal1E-1726686553

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000138035

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000138035homo_sapiensENSP0000040064696.934995.6577nomascus_leucogenysENSNLEP0000001143098.316197.0207
ENSG00000138035homo_sapiensENSP0000040064689.910689.7829pan_paniscusENSPPAP0000000625499.716799.5751
ENSG00000138035homo_sapiensENSP0000040064689.527588.7612pongo_abeliiENSPPYP0000001383399.715598.862
ENSG00000138035homo_sapiensENSP0000040064698.978398.4674pan_troglodytesENSPTRP0000008415698.85298.3418
ENSG00000138035homo_sapiensENSP0000040064699.872399.6169gorilla_gorillaENSGGOP0000000672699.872399.6169
ENSG00000138035homo_sapiensENSP0000040064691.698683.2695ornithorhynchus_anatinusENSOANP0000003463287.667979.6093
ENSG00000138035homo_sapiensENSP0000040064693.74284.9298sarcophilus_harrisiiENSSHAP0000003615793.503284.7134
ENSG00000138035homo_sapiensENSP0000040064679.821276.6283choloepus_hoffmanniENSCHOP0000000653786.206982.7586
ENSG00000138035homo_sapiensENSP0000040064696.807292.0817dasypus_novemcinctusENSDNOP0000002498696.683791.9643
ENSG00000138035homo_sapiensENSP0000040064687.611782.5032erinaceus_europaeusENSEEUP0000001426087.166582.0839
ENSG00000138035homo_sapiensENSP0000040064673.818668.327echinops_telfairiENSETEP0000000127973.724568.2398
ENSG00000138035homo_sapiensENSP0000040064698.21296.0409callithrix_jacchusENSCJAP0000001802798.086795.9184
ENSG00000138035homo_sapiensENSP0000040064697.573496.2963cercocebus_atysENSCATP0000001530398.074596.7908
ENSG00000138035homo_sapiensENSP0000040064698.595197.5734macaca_fascicularisENSMFAP0000000444998.595197.5734
ENSG00000138035homo_sapiensENSP0000040064698.722997.5734macaca_mulattaENSMMUP0000000918998.722997.5734
ENSG00000138035homo_sapiensENSP0000040064693.486692.2094macaca_nemestrinaENSMNEP0000003032397.082295.756
ENSG00000138035homo_sapiensENSP0000040064692.464991.3155papio_anubisENSPANP0000002361299.314198.0796
ENSG00000138035homo_sapiensENSP0000040064690.549289.272papio_anubisENSPANP0000005911798.472297.0833
ENSG00000138035homo_sapiensENSP0000040064698.722997.7011papio_anubisENSPANP0000000882698.722997.7011
ENSG00000138035homo_sapiensENSP0000040064695.402394.2529mandrillus_leucophaeusENSMLEP0000002907698.548897.3615
ENSG00000138035homo_sapiensENSP0000040064690.676986.9732tursiops_truncatusENSTTRP0000000002797.393793.4156
ENSG00000138035homo_sapiensENSP0000040064697.701193.4866vulpes_vulpesENSVVUP0000001367497.576593.3673
ENSG00000138035homo_sapiensENSP0000040064696.42491.4432mus_spretusMGP_SPRETEiJ_P002729696.30191.3265
ENSG00000138035homo_sapiensENSP0000040064697.828994.3806equus_asinusENSEASP0000504775795.630592.2597
ENSG00000138035homo_sapiensENSP0000040064692.84888.1226capra_hircusENSCHIP0000003028695.532290.6702
ENSG00000138035homo_sapiensENSP0000040064691.315585.4406loxodonta_africanaENSLAFP0000001692591.082885.2229
ENSG00000138035homo_sapiensENSP0000040064651.213349.8084panthera_leoENSPLOP0000000217698.04495.3545
ENSG00000138035homo_sapiensENSP0000040064697.445793.9974ailuropoda_melanoleucaENSAMEP0000000404097.321493.8775
ENSG00000138035homo_sapiensENSP0000040064696.42491.6986bos_indicus_hybridENSBIXP0000501358996.42491.6986
ENSG00000138035homo_sapiensENSP0000040064697.190393.8697oryctolagus_cuniculusENSOCUP0000000596397.066393.75
ENSG00000138035homo_sapiensENSP0000040064697.828994.3806equus_caballusENSECAP0000001822393.528790.232
ENSG00000138035homo_sapiensENSP0000040064697.573493.742canis_lupus_familiarisENSCAFP0084501668397.44993.6225
ENSG00000138035homo_sapiensENSP0000040064697.701194.636panthera_pardusENSPPRP0000000567497.576594.5153
ENSG00000138035homo_sapiensENSP0000040064697.445793.1034marmota_marmota_marmotaENSMMMP0000000819197.321492.9847
ENSG00000138035homo_sapiensENSP0000040064695.657791.8263balaenoptera_musculusENSBMSP0001002614196.520692.6546
ENSG00000138035homo_sapiensENSP0000040064697.190391.6986cavia_porcellusENSCPOP0000000989497.190391.6986
ENSG00000138035homo_sapiensENSP0000040064697.573494.3806felis_catusENSFCAP0000001227597.44994.2602
ENSG00000138035homo_sapiensENSP0000040064684.80281.3538ursus_americanusENSUAMP0000002375395.677291.7867
ENSG00000138035homo_sapiensENSP0000040064692.975785.1852monodelphis_domesticaENSMODP0000000242092.738984.9682
ENSG00000138035homo_sapiensENSP0000040064694.763790.0383bison_bison_bisonENSBBBP0000001170193.216188.5678
ENSG00000138035homo_sapiensENSP0000040064696.42491.6986bison_bison_bisonENSBBBP0000000194496.42491.6986
ENSG00000138035homo_sapiensENSP0000040064696.168692.2094monodon_monocerosENSMMNP0001501315796.045992.0918
ENSG00000138035homo_sapiensENSP0000040064696.551792.7203sus_scrofaENSSSCP0000004525396.428692.602
ENSG00000138035homo_sapiensENSP0000040064697.190394.636microcebus_murinusENSMICP0000000855997.066394.5153
ENSG00000138035homo_sapiensENSP0000040064697.062692.2094octodon_degusENSODEP0000001648296.938892.0918
ENSG00000138035homo_sapiensENSP0000040064696.42491.5709jaculus_jaculusENSJJAP0000001780596.30191.4541
ENSG00000138035homo_sapiensENSP0000040064696.679491.954ovis_aries_rambouilletENSOARP0002000019296.556191.8367
ENSG00000138035homo_sapiensENSP0000040064697.701194.3806ursus_maritimusENSUMAP0000002585696.469193.1904
ENSG00000138035homo_sapiensENSP0000040064692.975789.3997ochotona_princepsENSOPRP0000000937292.975789.3997
ENSG00000138035homo_sapiensENSP0000040064696.296392.3372delphinapterus_leucasENSDLEP0000002508896.173592.2194
ENSG00000138035homo_sapiensENSP0000040064696.296392.4649physeter_catodonENSPCTP0000500684696.173592.3469
ENSG00000138035homo_sapiensENSP0000040064696.551791.8263mus_caroliMGP_CAROLIEiJ_P002595996.428691.7092
ENSG00000138035homo_sapiensENSP0000040064696.168691.1877mus_musculusENSMUSP0000002075696.168691.1877
ENSG00000138035homo_sapiensENSP0000040064696.679491.6986dipodomys_ordiiENSDORP0000001072396.679491.6986
ENSG00000138035homo_sapiensENSP0000040064697.701193.8697mustela_putorius_furoENSMPUP0000000232797.328293.5115
ENSG00000138035homo_sapiensENSP0000040064698.21295.53aotus_nancymaaeENSANAP0000001160298.086795.4082
ENSG00000138035homo_sapiensENSP0000040064695.274693.1034saimiri_boliviensis_boliviensisENSSBOP0000003278097.771995.5439
ENSG00000138035homo_sapiensENSP0000040064688.37883.7803vicugna_pacosENSVPAP0000000660688.37883.7803
ENSG00000138035homo_sapiensENSP0000040064698.722997.5734chlorocebus_sabaeusENSCSAP0000001035998.596997.449
ENSG00000138035homo_sapiensENSP0000040064667.305264.2401tupaia_belangeriENSTBEP0000000937767.048363.9949
ENSG00000138035homo_sapiensENSP0000040064696.168691.4432mesocricetus_auratusENSMAUP0000001371595.316590.6329
ENSG00000138035homo_sapiensENSP0000040064696.168692.3372phocoena_sinusENSPSNP0000001610596.045992.2194
ENSG00000138035homo_sapiensENSP0000040064697.062692.7203camelus_dromedariusENSCDRP0000503300391.01886.9461
ENSG00000138035homo_sapiensENSP0000040064696.807293.742carlito_syrichtaENSTSYP0000000607696.683793.6225
ENSG00000138035homo_sapiensENSP0000040064697.701194.5083panthera_tigris_altaicaENSPTIP0000001599397.576594.3878
ENSG00000138035homo_sapiensENSP0000040064696.168691.6986rattus_norvegicusENSRNOP0000000491996.045991.5816
ENSG00000138035homo_sapiensENSP0000040064621.711421.4559prolemur_simusENSPSMP0000002076194.972193.8548
ENSG00000138035homo_sapiensENSP0000040064696.168691.8263microtus_ochrogasterENSMOCP0000000352495.679891.3596
ENSG00000138035homo_sapiensENSP0000040064674.584971.1367sorex_araneusENSSARP0000001158374.300370.8651
ENSG00000138035homo_sapiensENSP0000040064696.296391.3155peromyscus_maniculatus_bairdiiENSPEMP0000000313895.928890.9669
ENSG00000138035homo_sapiensENSP0000040064696.42491.6986bos_mutusENSBMUP0000001928596.42491.6986
ENSG00000138035homo_sapiensENSP0000040064696.551791.4432mus_spicilegusENSMSIP0000002085696.428691.3265
ENSG00000138035homo_sapiensENSP0000040064696.168691.4432cricetulus_griseus_chok1gshdENSCGRP0000101033895.316590.6329
ENSG00000138035homo_sapiensENSP0000040064668.32766.0281pteropus_vampyrusENSPVAP0000000509568.239865.9439
ENSG00000138035homo_sapiensENSP0000040064696.551792.0817myotis_lucifugusENSMLUP0000000354696.06191.6137
ENSG00000138035homo_sapiensENSP0000040064692.975785.3129vombatus_ursinusENSVURP0001001825792.738985.0955
ENSG00000138035homo_sapiensENSP0000040064697.062692.4649rhinolophus_ferrumequinumENSRFEP0001001600496.938892.3469
ENSG00000138035homo_sapiensENSP0000040064697.445793.9974neovison_visonENSNVIP0000000447197.445793.9974
ENSG00000138035homo_sapiensENSP0000040064696.42491.6986bos_taurusENSBTAP0000001172996.42491.6986
ENSG00000138035homo_sapiensENSP0000040064618.263116.4751heterocephalus_glaber_femaleENSHGLP0000004438979.888372.067
ENSG00000138035homo_sapiensENSP0000040064696.551791.5709heterocephalus_glaber_femaleENSHGLP0000003575996.428691.4541
ENSG00000138035homo_sapiensENSP0000040064698.978397.4457rhinopithecus_bietiENSRBIP0000003909698.978397.4457
ENSG00000138035homo_sapiensENSP0000040064697.573493.742canis_lupus_dingoENSCAFP0002003460797.44993.6225
ENSG00000138035homo_sapiensENSP0000040064697.062692.7203sciurus_vulgarisENSSVLP0000503141197.062692.7203
ENSG00000138035homo_sapiensENSP0000040064693.231285.4406phascolarctos_cinereusENSPCIP0000001288992.993685.2229
ENSG00000138035homo_sapiensENSP0000040064682.1277.9055procavia_capensisENSPCAP0000001016588.324283.7912
ENSG00000138035homo_sapiensENSP0000040064695.913291.4432nannospalax_galiliENSNGAP0000002180195.304690.8629
ENSG00000138035homo_sapiensENSP0000040064618.007716.986nannospalax_galiliENSNGAP0000001434689.240584.1772
ENSG00000138035homo_sapiensENSP0000040064696.42491.6986bos_grunniensENSBGRP0000003009696.42491.6986
ENSG00000138035homo_sapiensENSP0000040064697.062692.4649chinchilla_lanigeraENSCLAP0000000893797.062692.4649
ENSG00000138035homo_sapiensENSP0000040064696.807292.0817cervus_hanglu_yarkandensisENSCHYP0000003683696.683791.9643
ENSG00000138035homo_sapiensENSP0000040064696.807292.4649catagonus_wagneriENSCWAP0000001582896.683792.3469
ENSG00000138035homo_sapiensENSP0000040064697.445792.848ictidomys_tridecemlineatusENSSTOP0000002058397.321492.7296
ENSG00000138035homo_sapiensENSP0000040064696.168692.3372otolemur_garnettiiENSOGAP0000000880395.437391.635
ENSG00000138035homo_sapiensENSP0000040064697.573495.4023cebus_imitatorENSCCAP0000004020397.44995.2806
ENSG00000138035homo_sapiensENSP0000040064697.445792.848urocitellus_parryiiENSUPAP0001001609097.321492.7296
ENSG00000138035homo_sapiensENSP0000040064696.42491.5709moschus_moschiferusENSMMSP0000000514194.493189.7372
ENSG00000138035homo_sapiensENSP0000040064698.978397.318rhinopithecus_roxellanaENSRROP0000003394798.978397.318
ENSG00000138035homo_sapiensENSP0000040064696.551791.6986mus_pahariMGP_PahariEiJ_P002999396.428691.5816
ENSG00000138035homo_sapiensENSP0000040064680.459876.3729propithecus_coquereliENSPCOP0000000872493.7588.9881
ENSG00000138035homo_sapiensENSP0000040064655.683338.825caenorhabditis_elegansBE0003N10.1.159.078641.1924
ENSG00000138035homo_sapiensENSP0000040064670.881254.4061drosophila_melanogasterFBpp029010371.984455.2529
ENSG00000138035homo_sapiensENSP0000040064683.01468.8378petromyzon_marinusENSPMAP0000000986288.555973.4332
ENSG00000138035homo_sapiensENSP0000040064665.389551.341eptatretus_burgeriENSEBUP0000001645077.811661.0942
ENSG00000138035homo_sapiensENSP0000040064688.888976.7561callorhinchus_miliiENSCMIP0000000571288.549676.4631
ENSG00000138035homo_sapiensENSP0000040064684.291273.0524latimeria_chalumnaeENSLACP0000001255291.160279.0055
ENSG00000138035homo_sapiensENSP0000040064687.994976.1175lepisosteus_oculatusENSLOCP0000001892186.557874.8744
ENSG00000138035homo_sapiensENSP0000040064686.717871.6475carassius_auratusENSCARP0000006330788.526773.1421
ENSG00000138035homo_sapiensENSP0000040064684.418972.9247astyanax_mexicanusENSAMXP0000003407291.298378.8674
ENSG00000138035homo_sapiensENSP0000040064684.80273.5632ictalurus_punctatusENSIPUP0000002163893.127680.7854
ENSG00000138035homo_sapiensENSP0000040064689.016675.2235esox_luciusENSELUP0000000355190.519576.4935
ENSG00000138035homo_sapiensENSP0000040064688.122674.7126electrophorus_electricusENSEEEP0000002543889.726976.0728
ENSG00000138035homo_sapiensENSP0000040064689.782975.2235oncorhynchus_kisutchENSOKIP0000511200891.298776.4935
ENSG00000138035homo_sapiensENSP0000040064686.973272.4138oncorhynchus_kisutchENSOKIP0000504325886.202571.7721
ENSG00000138035homo_sapiensENSP0000040064689.655275.7344oncorhynchus_mykissENSOMYP0000010229990.115576.1232
ENSG00000138035homo_sapiensENSP0000040064689.782975.4789oncorhynchus_mykissENSOMYP0000010002791.298776.7533
ENSG00000138035homo_sapiensENSP0000040064689.655275.7344salmo_salarENSSSAP0000002631890.115576.1232
ENSG00000138035homo_sapiensENSP0000040064688.250373.9464salmo_salarENSSSAP0000009962688.931874.5174
ENSG00000138035homo_sapiensENSP0000040064688.888974.7126salmo_truttaENSSTUP0000004379088.775574.6173
ENSG00000138035homo_sapiensENSP0000040064689.782975.6066salmo_truttaENSSTUP0000011401690.243975.9949
ENSG00000138035homo_sapiensENSP0000040064687.994972.9247gadus_morhuaENSGMOP0000003451886.885272.005
ENSG00000138035homo_sapiensENSP0000040064688.505775.2235fundulus_heteroclitusENSFHEP000000247359076.4935
ENSG00000138035homo_sapiensENSP0000040064684.291273.3078poecilia_reticulataENSPREP0000000441990.659378.8462
ENSG00000138035homo_sapiensENSP0000040064688.122675.4789xiphophorus_maculatusENSXMAP0000001696589.610476.7533
ENSG00000138035homo_sapiensENSP0000040064688.633575.2235oryzias_latipesENSORLP0000000543087.185973.995
ENSG00000138035homo_sapiensENSP0000040064682.503269.4764cyclopterus_lumpusENSCLMP0000504905283.140370.0129
ENSG00000138035homo_sapiensENSP0000040064686.717874.0741oreochromis_niloticusENSONIP0000000124688.526775.6193
ENSG00000138035homo_sapiensENSP0000040064688.37875.2235haplochromis_burtoniENSHBUP0000001130989.870176.4935
ENSG00000138035homo_sapiensENSP0000040064688.505775.4789astatotilapia_callipteraENSACLP000000358769076.7533
ENSG00000138035homo_sapiensENSP0000040064688.250374.4572sparus_aurataENSSAUP0001005548189.740375.7143
ENSG00000138035homo_sapiensENSP0000040064688.888975.4789lates_calcariferENSLCAP0001004693390.389676.7533
ENSG00000138035homo_sapiensENSP0000040064689.016676.6283xenopus_tropicalisENSXETP0000001338088.339776.0456
ENSG00000138035homo_sapiensENSP0000040064691.0680.8429chrysemys_picta_belliiENSCPBP0000002959389.460579.4228
ENSG00000138035homo_sapiensENSP0000040064689.910677.2669sphenodon_punctatusENSSPUP0000001525090.256477.5641
ENSG00000138035homo_sapiensENSP0000040064687.100976.2452crocodylus_porosusENSCPRP0000501980381.384271.2411
ENSG00000138035homo_sapiensENSP0000040064687.739575.8621laticauda_laticaudataENSLLTP0000002392786.415174.717
ENSG00000138035homo_sapiensENSP0000040064677.394667.1775notechis_scutatusENSNSUP0000002150584.401173.2591
ENSG00000138035homo_sapiensENSP0000040064681.864671.2644pseudonaja_textilisENSPTXP0000001344979.233668.974
ENSG00000138035homo_sapiensENSP0000040064682.758672.9247anas_platyrhynchos_platyrhynchosENSAPLP0000002157788.524678.0055
ENSG00000138035homo_sapiensENSP0000040064689.399778.5441gallus_gallusENSGALP0001002761287.576.875
ENSG00000138035homo_sapiensENSP0000040064686.717876.2452meleagris_gallopavoENSMGAP0000000153193.269282.0055
ENSG00000138035homo_sapiensENSP0000040064687.48476.6283serinus_canariaENSSCAP0000001953890.131678.9474
ENSG00000138035homo_sapiensENSP0000040064689.655278.5441parus_majorENSPMJP0000001923588.524677.5536
ENSG00000138035homo_sapiensENSP0000040064689.27277.5223anolis_carolinensisENSACAP0000002405388.593276.9328
ENSG00000138035homo_sapiensENSP0000040064669.348758.3653neolamprologus_brichardiENSNBRP0000001641280.92468.1073
ENSG00000138035homo_sapiensENSP0000040064688.122676.6283naja_najaENSNNAP0000000394586.2575
ENSG00000138035homo_sapiensENSP0000040064686.5976.2452podarcis_muralisENSPMRP0000000709488.743578.1414
ENSG00000138035homo_sapiensENSP0000040064687.48476.6283geospiza_fortisENSGFOP0000000588790.969579.6813
ENSG00000138035homo_sapiensENSP0000040064686.973276.6283taeniopygia_guttataENSTGUP0000000715890.438279.6813
ENSG00000138035homo_sapiensENSP0000040064688.505775.7344erpetoichthys_calabaricusENSECRP0000003219687.279674.6851
ENSG00000138035homo_sapiensENSP0000040064687.611774.3295kryptolebias_marmoratusENSKMAP0000002352589.090975.5844
ENSG00000138035homo_sapiensENSP0000040064690.293779.8212salvator_merianaeENSSMRP0000001893688.264778.0275
ENSG00000138035homo_sapiensENSP0000040064687.994974.3295oryzias_javanicusENSOJAP0000002247689.596975.6827
ENSG00000138035homo_sapiensENSP0000040064685.057572.9247amphilophus_citrinellusENSACIP0000001307991.862178.7586
ENSG00000138035homo_sapiensENSP0000040064687.867273.5632dicentrarchus_labraxENSDLAP0000507322289.234874.7082
ENSG00000138035homo_sapiensENSP0000040064685.057573.0524amphiprion_perculaENSAPEP0000000326391.35878.4636
ENSG00000138035homo_sapiensENSP0000040064688.633575.2235oryzias_sinensisENSOSIP0000003118387.185973.995
ENSG00000138035homo_sapiensENSP0000040064689.527578.9272pelodiscus_sinensisENSPSIP0000001487091.39580.5737
ENSG00000138035homo_sapiensENSP0000040064689.782980.5875gopherus_evgoodeiENSGEVP0000500404691.655882.2686
ENSG00000138035homo_sapiensENSP0000040064686.973278.6718chelonoidis_abingdoniiENSCABP0000001229088.556680.104
ENSG00000138035homo_sapiensENSP0000040064689.527575.3512seriola_dumeriliENSSDUP0000002560591.03976.6234
ENSG00000138035homo_sapiensENSP0000040064688.250372.9247cottoperca_gobioENSCGOP0000005255489.740374.1558
ENSG00000138035homo_sapiensENSP0000040064688.505778.1609struthio_camelus_australisENSSCUP0000000972392.154381.383
ENSG00000138035homo_sapiensENSP0000040064681.098371.0089anser_brachyrhynchusENSABRP0000002488683.442873.0618
ENSG00000138035homo_sapiensENSP0000040064687.739573.5632gasterosteus_aculeatusENSGACP0000001437988.989674.6114
ENSG00000138035homo_sapiensENSP0000040064682.503269.4764cynoglossus_semilaevisENSCSEP0000000118291.891977.3826
ENSG00000138035homo_sapiensENSP0000040064687.611775.6066poecilia_formosaENSPFOP0000001038089.090976.8831
ENSG00000138035homo_sapiensENSP0000040064683.780371.1367myripristis_murdjanENSMMDP0000504322587.935774.6649
ENSG00000138035homo_sapiensENSP0000040064688.761274.3295sander_luciopercaENSSLUP0000002699890.494875.7812
ENSG00000138035homo_sapiensENSP0000040064689.27278.4163strigops_habroptilaENSSHBP0000500332089.27278.4163
ENSG00000138035homo_sapiensENSP0000040064688.761276.1175amphiprion_ocellarisENSAOCP0000002961890.259777.4026
ENSG00000138035homo_sapiensENSP0000040064691.0681.0983terrapene_carolina_triunguisENSTMTP0000001988189.460579.6738
ENSG00000138035homo_sapiensENSP0000040064687.867274.2018hucho_huchoENSHHUP0000006311390.885176.7503
ENSG00000138035homo_sapiensENSP0000040064689.910675.8621hucho_huchoENSHHUP0000002876290.372376.2516
ENSG00000138035homo_sapiensENSP0000040064686.717873.4355betta_splendensENSBSLP0000005389687.953474.4819
ENSG00000138035homo_sapiensENSP0000040064689.399777.7778pygocentrus_nattereriENSPNAP0000002563891.027379.1938
ENSG00000138035homo_sapiensENSP0000040064688.37875.4789anabas_testudineusENSATEP0000005544289.870176.7533
ENSG00000138035homo_sapiensENSP0000040064689.399775.2235seriola_lalandi_dorsalisENSSLDP0000003039690.909176.4935
ENSG00000138035homo_sapiensENSP0000040064688.761274.0741labrus_bergyltaENSLBEP0000003709890.494875.5208
ENSG00000138035homo_sapiensENSP0000040064685.057572.5415pundamilia_nyerereiENSPNYP0000000047788.563875.5319
ENSG00000138035homo_sapiensENSP0000040064687.739574.9681mastacembelus_armatusENSMAMP0000005371889.453176.4323
ENSG00000138035homo_sapiensENSP0000040064687.739573.8186stegastes_partitusENSSPAP0000002241789.220875.0649
ENSG00000138035homo_sapiensENSP0000040064688.633574.7126oncorhynchus_tshawytschaENSOTSP0000508463988.633574.7126
ENSG00000138035homo_sapiensENSP0000040064689.527575.7344oncorhynchus_tshawytschaENSOTSP0000505924647.04739.7987
ENSG00000138035homo_sapiensENSP0000040064688.761275.7344acanthochromis_polyacanthusENSAPOP0000002357590.259777.013
ENSG00000138035homo_sapiensENSP0000040064689.782979.3103aquila_chrysaetos_chrysaetosENSACCP0002000730488.53978.2116
ENSG00000138035homo_sapiensENSP0000040064687.739575.0958nothobranchius_furzeriENSNFUP0001500659589.453176.5625
ENSG00000138035homo_sapiensENSP0000040064672.286161.3027cyprinodon_variegatusENSCVAP0000000819890.5676.8
ENSG00000138035homo_sapiensENSP0000040064688.888974.8404larimichthys_croceaENSLCRP0000502074790.980476.6013
ENSG00000138035homo_sapiensENSP0000040064681.609267.6884takifugu_rubripesENSTRUP0000008582480.175766.4994
ENSG00000138035homo_sapiensENSP0000040064687.48476.5006ficedula_albicollisENSFALP0000001169792.318180.7278
ENSG00000138035homo_sapiensENSP0000040064673.946460.5364hippocampus_comesENSHCOP0000000177487.727371.8182
ENSG00000138035homo_sapiensENSP0000040064686.334671.3921cyprinus_carpio_carpioENSCCRP0000015399886.005171.1196
ENSG00000138035homo_sapiensENSP0000040064679.182668.7101coturnix_japonicaENSCJPP0000502093788.825277.0774
ENSG00000138035homo_sapiensENSP0000040064687.739575.6066poecilia_latipinnaENSPLAP0000000672089.220876.8831
ENSG00000138035homo_sapiensENSP0000040064688.505775.4789maylandia_zebraENSMZEP000050367019076.7533
ENSG00000138035homo_sapiensENSP0000040064685.568373.0524tetraodon_nigroviridisENSTNIP0000001026889.692176.573
ENSG00000138035homo_sapiensENSP0000040064689.27275.6066paramormyrops_kingsleyaeENSPKIP0000000459987.814174.3719
ENSG00000138035homo_sapiensENSP0000040064688.888977.5223scleropages_formosusENSSFOP0001507209587.76876.5448
ENSG00000138035homo_sapiensENSP0000040064687.228673.9464leptobrachium_leishanenseENSLLEP0000002785386.785373.5705
ENSG00000138035homo_sapiensENSP0000040064687.994973.9464scophthalmus_maximusENSSMAP0000003014488.560474.4216
ENSG00000138035homo_sapiensENSP0000040064612.260510.8557oryzias_melastigmaENSOMEP0000002902271.641863.4328

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000175enables 3-5-RNA exonuclease activity2IBA,IDAHomo_sapiens(9606)Function
GO:0000957involved_in mitochondrial RNA catabolic process1IDAHomo_sapiens(9606)Process
GO:0000958involved_in mitochondrial mRNA catabolic process2IBA,IDAHomo_sapiens(9606)Process
GO:0000962involved_in positive regulation of mitochondrial RNA catabolic process1IDAHomo_sapiens(9606)Process
GO:0000964involved_in mitochondrial RNA 5-end processing1IMPHomo_sapiens(9606)Process
GO:0000965involved_in mitochondrial RNA 3-end processing2IBA,IMPHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0004654enables polyribonucleotide nucleotidyltransferase activity2IBA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005739is_active_in mitochondrion2IBA,IDAHomo_sapiens(9606)Component
GO:0005758located_in mitochondrial intermembrane space1IDAHomo_sapiens(9606)Component
GO:0005759located_in mitochondrial matrix1IEAHomo_sapiens(9606)Component
GO:0005789located_in endoplasmic reticulum membrane1IEAHomo_sapiens(9606)Component
GO:0005829is_active_in cytosol2IBA,IDAHomo_sapiens(9606)Component
GO:0006397involved_in mRNA processing1IEAHomo_sapiens(9606)Process
GO:0006401involved_in RNA catabolic process1IDAHomo_sapiens(9606)Process
GO:0006402involved_in mRNA catabolic process1IDAHomo_sapiens(9606)Process
GO:0008266enables poly(U) RNA binding1IDAHomo_sapiens(9606)Function
GO:0034046enables poly(G) binding1IDAHomo_sapiens(9606)Function
GO:0034599involved_in cellular response to oxidative stress1IDAHomo_sapiens(9606)Process
GO:0035198enables miRNA binding1IDAHomo_sapiens(9606)Function
GO:0035458involved_in cellular response to interferon-beta1IDAHomo_sapiens(9606)Process
GO:0035927involved_in RNA import into mitochondrion1IDAHomo_sapiens(9606)Process
GO:0035928involved_in rRNA import into mitochondrion1IDAHomo_sapiens(9606)Process
GO:0042788located_in polysomal ribosome1IEAHomo_sapiens(9606)Component
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0043457involved_in regulation of cellular respiration1ISSHomo_sapiens(9606)Process
GO:0045025part_of mitochondrial degradosome1IDAHomo_sapiens(9606)Component
GO:0045926involved_in negative regulation of growth1IDAHomo_sapiens(9606)Process
GO:0051260involved_in protein homooligomerization1IDAHomo_sapiens(9606)Process
GO:0051591involved_in response to cAMP1IEAHomo_sapiens(9606)Process
GO:0051726involved_in regulation of cell cycle1IDAHomo_sapiens(9606)Process
GO:0060416involved_in response to growth hormone1IEAHomo_sapiens(9606)Process
GO:0061014involved_in positive regulation of mRNA catabolic process1IMPHomo_sapiens(9606)Process
GO:0070207involved_in protein homotrimerization1IDAHomo_sapiens(9606)Process
GO:0070584involved_in mitochondrion morphogenesis1ISSHomo_sapiens(9606)Process
GO:0071042involved_in nuclear polyadenylation-dependent mRNA catabolic process1IDAHomo_sapiens(9606)Process
GO:0097222involved_in mitochondrial mRNA polyadenylation1IMPHomo_sapiens(9606)Process
GO:0097421involved_in liver regeneration1IEAHomo_sapiens(9606)Process
GO:2000627involved_in positive regulation of miRNA catabolic process1IDAHomo_sapiens(9606)Process
GO:2000772involved_in regulation of cellular senescence1IDAHomo_sapiens(9606)Process

Expression