RBP Type
Canonical_RBPs
Diseases
Flaviviruses HIV SARS-COV-2 SINV Dengue Zika
Drug
N.A.
Main interacting RNAs
tRNA
Moonlighting functions
N.A.
Localizations
N.A.
BulkPerturb-seq
Ensembl ID ENSG00000134001 Gene ID
1965 Accession
3265
Symbol
EIF2S1
Alias
EIF2;EIF-2;EIF2A;EIF-2A;EIF-2alpha
Full Name
eukaryotic translation initiation factor 2 subunit alpha
Status
Confidence
Length
26189 bases
Strand
Plus strand
Position
14 : 67360328 - 67386516
RNA binding domain
EIF_2_alpha , S1
Summary
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000256383
S1
PF00575 8.2e-15
1
ENSP00000256383
EIF_2_alpha
PF07541 1.5e-36
2
ENSP00000425299
S1
PF00575 8.2e-15
1
ENSP00000425299
EIF_2_alpha
PF07541 1.5e-36
2
ENSP00000451975
S1
PF00575 8.2e-15
1
ENSP00000451975
EIF_2_alpha
PF07541 1.2e-36
2
ENSP00000452034
S1
PF00575 9.8e-06
1
ENSP00000452034
EIF_2_alpha
PF07541 8.7e-37
2
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
35207490 Promising Assays for Examining a Putative Role of Ribosomal Heterogeneity in COVID-19 Susceptibility and Severity.
Yih-Horng Shiao
2022-01-28
Life (Basel, Switzerland)
31311889 Mitochondrial and ribosomal biogenesis are new hallmarks of stemness, oncometabolism and biomass accumulation in cancer: Mito-stemness and ribo-stemness features.
Maria Peiris-Pagès
2019-07-16
Aging
Name
Transcript ID
bp
Protein
Translation ID
EIF2S1-201
ENST00000256383
4154
315aa
ENSP00000256383
EIF2S1-205
ENST00000556724
527
No protein
-
EIF2S1-206
ENST00000557310
999
273aa
ENSP00000451975
EIF2S1-202
ENST00000466499
2390
315aa
ENSP00000425299
EIF2S1-204
ENST00000555876
783
252aa
ENSP00000452034
EIF2S1-203
ENST00000554332
534
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000134001
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000134001 homo_sapiens ENSP00000256383 100 100 nomascus_leucogenys ENSNLEP00000000790 100 100 ENSG00000134001 homo_sapiens ENSP00000256383 100 100 pan_paniscus ENSPPAP00000037407 100 100 ENSG00000134001 homo_sapiens ENSP00000256383 100 100 pongo_abelii ENSPPYP00000006729 100 100 ENSG00000134001 homo_sapiens ENSP00000256383 100 100 pan_troglodytes ENSPTRP00000010961 100 100 ENSG00000134001 homo_sapiens ENSP00000256383 100 100 gorilla_gorilla ENSGGOP00000001580 100 100 ENSG00000134001 homo_sapiens ENSP00000256383 98.7302 97.7778 ornithorhynchus_anatinus ENSOANP00000052582 98.7302 97.7778 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.0952 sarcophilus_harrisii ENSSHAP00000011417 99.3651 98.0952 ENSG00000134001 homo_sapiens ENSP00000256383 83.8095 81.2698 notamacropus_eugenii ENSMEUP00000010729 86.5574 83.9344 ENSG00000134001 homo_sapiens ENSP00000256383 98.7302 96.1905 choloepus_hoffmanni ENSCHOP00000007983 98.7302 96.1905 ENSG00000134001 homo_sapiens ENSP00000256383 65.7143 64.7619 choloepus_hoffmanni ENSCHOP00000003311 69.697 68.6869 ENSG00000134001 homo_sapiens ENSP00000256383 98.7302 97.4603 choloepus_hoffmanni ENSCHOP00000003741 98.7302 97.4603 ENSG00000134001 homo_sapiens ENSP00000256383 93.3333 90.4762 dasypus_novemcinctus ENSDNOP00000017257 92.4528 89.6226 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 erinaceus_europaeus ENSEEUP00000009314 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 86.0317 84.4444 echinops_telfairi ENSETEP00000015436 98.9051 97.0803 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.6825 callithrix_jacchus ENSCJAP00000028344 99.6825 99.6825 ENSG00000134001 homo_sapiens ENSP00000256383 100 100 cercocebus_atys ENSCATP00000043114 100 100 ENSG00000134001 homo_sapiens ENSP00000256383 100 100 macaca_fascicularis ENSMFAP00000059248 100 100 ENSG00000134001 homo_sapiens ENSP00000256383 100 100 macaca_mulatta ENSMMUP00000028218 100 100 ENSG00000134001 homo_sapiens ENSP00000256383 100 100 macaca_nemestrina ENSMNEP00000018182 100 100 ENSG00000134001 homo_sapiens ENSP00000256383 100 100 papio_anubis ENSPANP00000017115 100 100 ENSG00000134001 homo_sapiens ENSP00000256383 100 100 mandrillus_leucophaeus ENSMLEP00000035060 100 100 ENSG00000134001 homo_sapiens ENSP00000256383 89.2064 88.254 tursiops_truncatus ENSTTRP00000014979 89.2064 88.254 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 vulpes_vulpes ENSVVUP00000000763 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 86.6667 86.3492 mus_spretus MGP_SPRETEiJ_P0034141 70.3608 70.1031 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.7302 equus_asinus ENSEASP00005012496 99.3651 98.7302 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 capra_hircus ENSCHIP00000007635 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 97.4603 loxodonta_africana ENSLAFP00000022368 99.3651 97.4603 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.7302 panthera_leo ENSPLOP00000018828 99.3651 98.7302 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.7302 ailuropoda_melanoleuca ENSAMEP00000008655 99.3651 98.7302 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 bos_indicus_hybrid ENSBIXP00005001227 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 50.1587 50.1587 bos_indicus_hybrid ENSBIXP00005017860 99.3711 99.3711 ENSG00000134001 homo_sapiens ENSP00000256383 92.381 92.0635 oryctolagus_cuniculus ENSOCUP00000033238 99.6575 99.3151 ENSG00000134001 homo_sapiens ENSP00000256383 93.6508 91.746 equus_caballus ENSECAP00000088260 93.0599 91.1672 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 canis_lupus_familiaris ENSCAFP00845004658 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.7302 panthera_pardus ENSPPRP00000005052 99.3651 98.7302 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 marmota_marmota_marmota ENSMMMP00000024288 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 79.0476 75.5556 balaenoptera_musculus ENSBMSP00010007124 94.3182 90.1515 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.7302 balaenoptera_musculus ENSBMSP00010002038 99.3651 98.7302 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 cavia_porcellus ENSCPOP00000026904 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.7302 felis_catus ENSFCAP00000019535 99.3651 98.7302 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.7302 ursus_americanus ENSUAMP00000010925 99.3651 98.7302 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.0952 monodelphis_domestica ENSMODP00000012403 99.3651 98.0952 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 bison_bison_bison ENSBBBP00000015815 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.4127 monodon_monoceros ENSMMNP00015017494 86.9444 86.1111 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 sus_scrofa ENSSSCP00000037333 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.7302 microcebus_murinus ENSMICP00000044673 99.6815 99.0446 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.7302 octodon_degus ENSODEP00000017854 99.3651 98.7302 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.4127 jaculus_jaculus ENSJJAP00000019400 99.3651 98.4127 ENSG00000134001 homo_sapiens ENSP00000256383 99.0476 98.4127 ovis_aries_rambouillet ENSOARP00020031315 99.0476 98.4127 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.7302 ovis_aries_rambouillet ENSOARP00020006684 99.3651 98.7302 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 98.7302 ovis_aries_rambouillet ENSOARP00020024207 99.6825 98.7302 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.7302 ursus_maritimus ENSUMAP00000014448 99.3651 98.7302 ENSG00000134001 homo_sapiens ENSP00000256383 97.7778 96.1905 ochotona_princeps ENSOPRP00000004158 98.0892 96.4968 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.4127 delphinapterus_leucas ENSDLEP00000016405 99.3651 98.4127 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.7302 physeter_catodon ENSPCTP00005020028 99.3651 98.7302 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 mus_caroli MGP_CAROLIEiJ_P0032628 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 mus_musculus ENSMUSP00000071214 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.7302 mustela_putorius_furo ENSMPUP00000007008 99.3651 98.7302 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.6825 aotus_nancymaae ENSANAP00000013418 99.6825 99.6825 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.6825 saimiri_boliviensis_boliviensis ENSSBOP00000040236 99.6825 99.6825 ENSG00000134001 homo_sapiens ENSP00000256383 87.619 86.9841 vicugna_pacos ENSVPAP00000005296 91.0891 90.429 ENSG00000134001 homo_sapiens ENSP00000256383 100 100 chlorocebus_sabaeus ENSCSAP00000009490 100 100 ENSG00000134001 homo_sapiens ENSP00000256383 63.8095 62.5397 tupaia_belangeri ENSTBEP00000009237 73.3577 71.8978 ENSG00000134001 homo_sapiens ENSP00000256383 72.0635 65.3968 mesocricetus_auratus ENSMAUP00000000683 88.6719 80.4688 ENSG00000134001 homo_sapiens ENSP00000256383 99.0476 98.0952 mesocricetus_auratus ENSMAUP00000015309 99.0476 98.0952 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.4127 phocoena_sinus ENSPSNP00000009868 99.3651 98.4127 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 camelus_dromedarius ENSCDRP00005003431 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.7302 carlito_syrichta ENSTSYP00000013011 99.3651 98.7302 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.7302 panthera_tigris_altaica ENSPTIP00000022929 99.3651 98.7302 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 rattus_norvegicus ENSRNOP00000013375 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 prolemur_simus ENSPSMP00000016729 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 80.6349 76.5079 microtus_ochrogaster ENSMOCP00000014264 90.3915 85.7651 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 97.4603 microtus_ochrogaster ENSMOCP00000004188 99.6825 97.4603 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.7302 sorex_araneus ENSSARP00000010549 99.3651 98.7302 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 98.0952 peromyscus_maniculatus_bairdii ENSPEMP00000005664 99.6825 98.0952 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 bos_mutus ENSBMUP00000011701 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 mus_spicilegus ENSMSIP00000017711 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 99.0476 98.0952 cricetulus_griseus_chok1gshd ENSCGRP00001015135 99.0476 98.0952 ENSG00000134001 homo_sapiens ENSP00000256383 96.1905 94.6032 pteropus_vampyrus ENSPVAP00000002871 98.6971 97.0684 ENSG00000134001 homo_sapiens ENSP00000256383 96.8254 94.6032 myotis_lucifugus ENSMLUP00000004042 96.519 94.3038 ENSG00000134001 homo_sapiens ENSP00000256383 99.0476 97.7778 vombatus_ursinus ENSVURP00010030674 99.0476 97.7778 ENSG00000134001 homo_sapiens ENSP00000256383 99.0476 98.4127 rhinolophus_ferrumequinum ENSRFEP00010000991 99.0476 98.4127 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 97.7778 neovison_vison ENSNVIP00000011607 99.3651 97.7778 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 bos_taurus ENSBTAP00000066638 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 99.3651 98.7302 heterocephalus_glaber_female ENSHGLP00000021799 96.3077 95.6923 ENSG00000134001 homo_sapiens ENSP00000256383 100 100 rhinopithecus_bieti ENSRBIP00000039482 100 100 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 canis_lupus_dingo ENSCAFP00020008082 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 98.7302 96.5079 sciurus_vulgaris ENSSVLP00005027205 98.7302 96.5079 ENSG00000134001 homo_sapiens ENSP00000256383 77.4603 73.3333 sciurus_vulgaris ENSSVLP00005012408 92.0755 87.1698 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 sciurus_vulgaris ENSSVLP00005018517 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 99.0476 97.7778 phascolarctos_cinereus ENSPCIP00000006182 99.0476 97.7778 ENSG00000134001 homo_sapiens ENSP00000256383 84.127 82.5397 procavia_capensis ENSPCAP00000002440 84.127 82.5397 ENSG00000134001 homo_sapiens ENSP00000256383 73.3333 67.9365 nannospalax_galili ENSNGAP00000011813 88.1679 81.6794 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 nannospalax_galili ENSNGAP00000005623 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 bos_grunniens ENSBGRP00000009081 96.319 95.7055 ENSG00000134001 homo_sapiens ENSP00000256383 50.1587 50.1587 bos_grunniens ENSBGRP00000028058 99.3711 99.3711 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 chinchilla_lanigera ENSCLAP00000004572 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 cervus_hanglu_yarkandensis ENSCHYP00000018392 81.3472 80.829 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 catagonus_wagneri ENSCWAP00000029478 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 ictidomys_tridecemlineatus ENSSTOP00000001402 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 otolemur_garnettii ENSOGAP00000018737 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.6825 cebus_imitator ENSCCAP00000021588 99.6825 99.6825 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 urocitellus_parryii ENSUPAP00010014927 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 99.0476 moschus_moschiferus ENSMMSP00000018921 99.6825 99.0476 ENSG00000134001 homo_sapiens ENSP00000256383 89.8413 87.9365 rhinopithecus_roxellana ENSRROP00000011742 95.9322 93.8983 ENSG00000134001 homo_sapiens ENSP00000256383 99.6825 98.7302 mus_pahari MGP_PahariEiJ_P0082739 99.6825 98.7302 ENSG00000134001 homo_sapiens ENSP00000256383 92.0635 91.1111 propithecus_coquereli ENSPCOP00000017635 98.3051 97.2881 ENSG00000134001 homo_sapiens ENSP00000256383 81.9048 76.1905 propithecus_coquereli ENSPCOP00000015643 87.7551 81.6327 ENSG00000134001 homo_sapiens ENSP00000256383 78.0952 75.5556 propithecus_coquereli ENSPCOP00000013264 95.7198 92.607 ENSG00000134001 homo_sapiens ENSP00000256383 73.6508 53.9683 caenorhabditis_elegans Y37E3.10a.1 67.8363 49.7076 ENSG00000134001 homo_sapiens ENSP00000256383 75.873 61.2698 drosophila_melanogaster FBpp0309768 70.088 56.5982 ENSG00000134001 homo_sapiens ENSP00000256383 86.0317 79.3651 petromyzon_marinus ENSPMAP00000007713 79.2398 73.0994 ENSG00000134001 homo_sapiens ENSP00000256383 86.6667 77.4603 eptatretus_burgeri ENSEBUP00000021551 95.7895 85.614 ENSG00000134001 homo_sapiens ENSP00000256383 96.8254 91.746 callorhinchus_milii ENSCMIP00000021326 92.7052 87.8419 ENSG00000134001 homo_sapiens ENSP00000256383 98.0952 93.6508 latimeria_chalumnae ENSLACP00000010465 98.0952 93.6508 ENSG00000134001 homo_sapiens ENSP00000256383 97.1429 95.2381 lepisosteus_oculatus ENSLOCP00000017450 96.8354 94.9367 ENSG00000134001 homo_sapiens ENSP00000256383 97.4603 92.6984 clupea_harengus ENSCHAP00000024470 97.4603 92.6984 ENSG00000134001 homo_sapiens ENSP00000256383 97.1429 94.2857 danio_rerio ENSDARP00000068470 97.1429 94.2857 ENSG00000134001 homo_sapiens ENSP00000256383 96.8254 93.6508 danio_rerio ENSDARP00000026560 96.8254 93.6508 ENSG00000134001 homo_sapiens ENSP00000256383 96.5079 93.3333 carassius_auratus ENSCARP00000077702 87.106 84.2407 ENSG00000134001 homo_sapiens ENSP00000256383 96.8254 93.0159 carassius_auratus ENSCARP00000089634 96.8254 93.0159 ENSG00000134001 homo_sapiens ENSP00000256383 96.8254 93.3333 carassius_auratus ENSCARP00000132269 96.8254 93.3333 ENSG00000134001 homo_sapiens ENSP00000256383 96.1905 92.381 carassius_auratus ENSCARP00000107639 96.1905 92.381 ENSG00000134001 homo_sapiens ENSP00000256383 96.8254 93.3333 carassius_auratus ENSCARP00000057707 82.4324 79.4595 ENSG00000134001 homo_sapiens ENSP00000256383 96.1905 92.0635 carassius_auratus ENSCARP00000085931 96.1905 92.0635 ENSG00000134001 homo_sapiens ENSP00000256383 98.0952 94.9206 astyanax_mexicanus ENSAMXP00000037691 98.0952 94.9206 ENSG00000134001 homo_sapiens ENSP00000256383 97.7778 94.2857 ictalurus_punctatus ENSIPUP00000031213 97.7778 94.2857 ENSG00000134001 homo_sapiens ENSP00000256383 96.1905 93.0159 esox_lucius ENSELUP00000025196 96.1905 93.0159 ENSG00000134001 homo_sapiens ENSP00000256383 96.1905 92.381 esox_lucius ENSELUP00000049452 86.0795 82.6705 ENSG00000134001 homo_sapiens ENSP00000256383 97.7778 93.0159 electrophorus_electricus ENSEEEP00000026423 97.7778 93.0159 ENSG00000134001 homo_sapiens ENSP00000256383 98.0952 93.9683 electrophorus_electricus ENSEEEP00000007899 98.0952 93.9683 ENSG00000134001 homo_sapiens ENSP00000256383 95.5556 91.4286 oncorhynchus_kisutch ENSOKIP00005114970 95.5556 91.4286 ENSG00000134001 homo_sapiens ENSP00000256383 96.1905 91.746 oncorhynchus_kisutch ENSOKIP00005027415 96.1905 91.746 ENSG00000134001 homo_sapiens ENSP00000256383 95.5556 90.7936 oncorhynchus_kisutch ENSOKIP00005052492 95.5556 90.7936 ENSG00000134001 homo_sapiens ENSP00000256383 95.5556 91.4286 oncorhynchus_mykiss ENSOMYP00000052718 95.5556 91.4286 ENSG00000134001 homo_sapiens ENSP00000256383 95.5556 90.7936 oncorhynchus_mykiss ENSOMYP00000071760 95.5556 90.7936 ENSG00000134001 homo_sapiens ENSP00000256383 96.1905 91.746 oncorhynchus_mykiss ENSOMYP00000056867 67.4833 64.3653 ENSG00000134001 homo_sapiens ENSP00000256383 83.8095 74.2857 salmo_salar ENSSSAP00000038664 85.4369 75.7282 ENSG00000134001 homo_sapiens ENSP00000256383 88.8889 84.7619 salmo_salar ENSSSAP00000078147 95.2381 90.8163 ENSG00000134001 homo_sapiens ENSP00000256383 96.1905 91.746 salmo_salar ENSSSAP00000082264 94.9843 90.5956 ENSG00000134001 homo_sapiens ENSP00000256383 88.5714 81.5873 salmo_salar ENSSSAP00000128728 82.7893 76.2611 ENSG00000134001 homo_sapiens ENSP00000256383 95.5556 91.746 salmo_trutta ENSSTUP00000055002 95.5556 91.746 ENSG00000134001 homo_sapiens ENSP00000256383 96.1905 91.746 salmo_trutta ENSSTUP00000114819 96.1905 91.746 ENSG00000134001 homo_sapiens ENSP00000256383 95.5556 91.1111 salmo_trutta ENSSTUP00000114437 95.5556 91.1111 ENSG00000134001 homo_sapiens ENSP00000256383 78.7302 71.746 salmo_trutta ENSSTUP00000076374 87.3239 79.5775 ENSG00000134001 homo_sapiens ENSP00000256383 97.4603 93.9683 gadus_morhua ENSGMOP00000003494 97.4603 93.9683 ENSG00000134001 homo_sapiens ENSP00000256383 97.1429 94.6032 fundulus_heteroclitus ENSFHEP00000022871 97.1429 94.6032 ENSG00000134001 homo_sapiens ENSP00000256383 86.9841 82.5397 poecilia_reticulata ENSPREP00000012662 88.3871 83.871 ENSG00000134001 homo_sapiens ENSP00000256383 97.1429 94.2857 xiphophorus_maculatus ENSXMAP00000026772 97.1429 94.2857 ENSG00000134001 homo_sapiens ENSP00000256383 96.8254 93.3333 cyclopterus_lumpus ENSCLMP00005039689 96.8254 93.3333 ENSG00000134001 homo_sapiens ENSP00000256383 97.4603 94.6032 oreochromis_niloticus ENSONIP00000007465 97.4603 94.6032 ENSG00000134001 homo_sapiens ENSP00000256383 97.4603 93.9683 haplochromis_burtoni ENSHBUP00000016452 97.4603 93.9683 ENSG00000134001 homo_sapiens ENSP00000256383 97.4603 94.2857 astatotilapia_calliptera ENSACLP00000036230 97.4603 94.2857 ENSG00000134001 homo_sapiens ENSP00000256383 97.4603 94.2857 sparus_aurata ENSSAUP00010010750 97.4603 94.2857 ENSG00000134001 homo_sapiens ENSP00000256383 92.381 88.5714 lates_calcarifer ENSLCAP00010038622 96.3576 92.3841 ENSG00000134001 homo_sapiens ENSP00000256383 73.3333 61.5873 xenopus_tropicalis ENSXETP00000086589 63.1148 53.0055 ENSG00000134001 homo_sapiens ENSP00000256383 98.4127 93.6508 xenopus_tropicalis ENSXETP00000086967 96.2733 91.6149 ENSG00000134001 homo_sapiens ENSP00000256383 99.0476 97.7778 chrysemys_picta_bellii ENSCPBP00000008102 99.0476 97.7778 ENSG00000134001 homo_sapiens ENSP00000256383 98.0952 96.1905 sphenodon_punctatus ENSSPUP00000017776 98.0952 96.1905 ENSG00000134001 homo_sapiens ENSP00000256383 99.0476 97.4603 crocodylus_porosus ENSCPRP00005025262 99.0476 97.4603 ENSG00000134001 homo_sapiens ENSP00000256383 98.4127 95.873 laticauda_laticaudata ENSLLTP00000016064 98.4127 95.873 ENSG00000134001 homo_sapiens ENSP00000256383 98.4127 95.873 notechis_scutatus ENSNSUP00000024491 98.4127 95.873 ENSG00000134001 homo_sapiens ENSP00000256383 98.4127 95.873 pseudonaja_textilis ENSPTXP00000017562 98.4127 95.873 ENSG00000134001 homo_sapiens ENSP00000256383 42.5397 38.4127 anas_platyrhynchos_platyrhynchos ENSAPLP00000027807 80.2395 72.4551 ENSG00000134001 homo_sapiens ENSP00000256383 98.7302 97.1429 gallus_gallus ENSGALP00010028485 95.3988 93.865 ENSG00000134001 homo_sapiens ENSP00000256383 98.7302 97.1429 meleagris_gallopavo ENSMGAP00000012569 98.7302 97.1429 ENSG00000134001 homo_sapiens ENSP00000256383 99.0476 97.4603 serinus_canaria ENSSCAP00000017091 99.0476 97.4603 ENSG00000134001 homo_sapiens ENSP00000256383 99.0476 97.4603 parus_major ENSPMJP00000020399 99.0476 97.4603 ENSG00000134001 homo_sapiens ENSP00000256383 99.0476 97.4603 anolis_carolinensis ENSACAP00000005888 99.0476 97.4603 ENSG00000134001 homo_sapiens ENSP00000256383 97.4603 94.2857 neolamprologus_brichardi ENSNBRP00000029172 97.4603 94.2857 ENSG00000134001 homo_sapiens ENSP00000256383 98.4127 95.873 naja_naja ENSNNAP00000012768 98.4127 95.873 ENSG00000134001 homo_sapiens ENSP00000256383 99.0476 97.4603 geospiza_fortis ENSGFOP00000010654 99.0476 97.4603 ENSG00000134001 homo_sapiens ENSP00000256383 99.0476 97.4603 taeniopygia_guttata ENSTGUP00000037595 91.2281 89.7661 ENSG00000134001 homo_sapiens ENSP00000256383 97.4603 94.2857 erpetoichthys_calabaricus ENSECRP00000020092 82.5269 79.8387 ENSG00000134001 homo_sapiens ENSP00000256383 97.4603 93.9683 kryptolebias_marmoratus ENSKMAP00000025510 97.4603 93.9683 ENSG00000134001 homo_sapiens ENSP00000256383 98.0952 95.873 salvator_merianae ENSSMRP00000012054 98.0952 95.873 ENSG00000134001 homo_sapiens ENSP00000256383 97.1429 94.2857 oryzias_javanicus ENSOJAP00000036534 97.1429 94.2857 ENSG00000134001 homo_sapiens ENSP00000256383 97.1429 94.2857 amphilophus_citrinellus ENSACIP00000018226 97.1429 94.2857 ENSG00000134001 homo_sapiens ENSP00000256383 97.4603 94.2857 dicentrarchus_labrax ENSDLAP00005056749 97.4603 94.2857 ENSG00000134001 homo_sapiens ENSP00000256383 97.4603 93.9683 amphiprion_percula ENSAPEP00000013533 97.4603 93.9683 ENSG00000134001 homo_sapiens ENSP00000256383 98.7302 97.4603 pelodiscus_sinensis ENSPSIP00000015973 98.7302 97.4603 ENSG00000134001 homo_sapiens ENSP00000256383 98.7302 97.1429 gopherus_evgoodei ENSGEVP00005025126 98.7302 97.1429 ENSG00000134001 homo_sapiens ENSP00000256383 98.7302 96.8254 chelonoidis_abingdonii ENSCABP00000021895 98.7302 96.8254 ENSG00000134001 homo_sapiens ENSP00000256383 86.6667 82.2222 seriola_dumerili ENSSDUP00000005237 82.7273 78.4848 ENSG00000134001 homo_sapiens ENSP00000256383 96.8254 93.0159 cottoperca_gobio ENSCGOP00000039819 96.8254 93.0159 ENSG00000134001 homo_sapiens ENSP00000256383 99.0476 97.4603 struthio_camelus_australis ENSSCUP00000008894 99.0476 97.4603 ENSG00000134001 homo_sapiens ENSP00000256383 89.2064 85.3968 anser_brachyrhynchus ENSABRP00000012033 83.1361 79.5858 ENSG00000134001 homo_sapiens ENSP00000256383 96.1905 91.746 gasterosteus_aculeatus ENSGACP00000011375 96.1905 91.746 ENSG00000134001 homo_sapiens ENSP00000256383 94.2857 90.1587 cynoglossus_semilaevis ENSCSEP00000005751 77.3438 73.9583 ENSG00000134001 homo_sapiens ENSP00000256383 97.1429 94.2857 poecilia_formosa ENSPFOP00000018891 80.1047 77.7487 ENSG00000134001 homo_sapiens ENSP00000256383 97.7778 94.6032 myripristis_murdjan ENSMMDP00005043205 97.7778 94.6032 ENSG00000134001 homo_sapiens ENSP00000256383 97.1429 93.9683 sander_lucioperca ENSSLUP00000042978 97.1429 93.9683 ENSG00000134001 homo_sapiens ENSP00000256383 99.0476 97.4603 strigops_habroptila ENSSHBP00005022752 99.0476 97.4603 ENSG00000134001 homo_sapiens ENSP00000256383 97.4603 93.9683 amphiprion_ocellaris ENSAOCP00000029189 97.4603 93.9683 ENSG00000134001 homo_sapiens ENSP00000256383 99.0476 97.4603 terrapene_carolina_triunguis ENSTMTP00000010288 99.0476 97.4603 ENSG00000134001 homo_sapiens ENSP00000256383 95.2381 91.4286 hucho_hucho ENSHHUP00000034832 95.2381 91.4286 ENSG00000134001 homo_sapiens ENSP00000256383 40.6349 35.5556 hucho_hucho ENSHHUP00000062905 74.8538 65.4971 ENSG00000134001 homo_sapiens ENSP00000256383 95.2381 90.7936 hucho_hucho ENSHHUP00000002846 95.2381 90.7936 ENSG00000134001 homo_sapiens ENSP00000256383 96.1905 92.0635 hucho_hucho ENSHHUP00000039786 96.1905 92.0635 ENSG00000134001 homo_sapiens ENSP00000256383 97.1429 93.9683 betta_splendens ENSBSLP00000011561 97.1429 93.9683 ENSG00000134001 homo_sapiens ENSP00000256383 97.4603 93.9683 pygocentrus_nattereri ENSPNAP00000005893 97.4603 93.9683 ENSG00000134001 homo_sapiens ENSP00000256383 97.4603 94.6032 pygocentrus_nattereri ENSPNAP00000007968 97.4603 94.6032 ENSG00000134001 homo_sapiens ENSP00000256383 97.1429 93.9683 anabas_testudineus ENSATEP00000046172 97.1429 93.9683 ENSG00000134001 homo_sapiens ENSP00000256383 71.1111 52.0635 saccharomyces_cerevisiae YJR007W 73.6842 53.9474 ENSG00000134001 homo_sapiens ENSP00000256383 97.4603 93.9683 seriola_lalandi_dorsalis ENSSLDP00000031996 97.4603 93.9683 ENSG00000134001 homo_sapiens ENSP00000256383 85.3968 81.2698 labrus_bergylta ENSLBEP00000038782 93.4028 88.8889 ENSG00000134001 homo_sapiens ENSP00000256383 91.4286 87.619 labrus_bergylta ENSLBEP00000014113 96.3211 92.3077 ENSG00000134001 homo_sapiens ENSP00000256383 97.4603 93.9683 pundamilia_nyererei ENSPNYP00000030933 97.4603 93.9683 ENSG00000134001 homo_sapiens ENSP00000256383 98.0952 94.2857 mastacembelus_armatus ENSMAMP00000006822 98.0952 94.2857 ENSG00000134001 homo_sapiens ENSP00000256383 97.1429 93.3333 stegastes_partitus ENSSPAP00000021406 97.1429 93.3333 ENSG00000134001 homo_sapiens ENSP00000256383 95.5556 91.4286 oncorhynchus_tshawytscha ENSOTSP00005008035 95.5556 91.4286 ENSG00000134001 homo_sapiens ENSP00000256383 95.2381 90.4762 oncorhynchus_tshawytscha ENSOTSP00005025320 95.2381 90.4762 ENSG00000134001 homo_sapiens ENSP00000256383 96.1905 91.746 oncorhynchus_tshawytscha ENSOTSP00005006700 96.1905 91.746 ENSG00000134001 homo_sapiens ENSP00000256383 97.4603 93.9683 acanthochromis_polyacanthus ENSAPOP00000013783 97.4603 93.9683 ENSG00000134001 homo_sapiens ENSP00000256383 99.0476 97.4603 aquila_chrysaetos_chrysaetos ENSACCP00020005679 99.0476 97.4603 ENSG00000134001 homo_sapiens ENSP00000256383 97.1429 93.9683 nothobranchius_furzeri ENSNFUP00015001107 97.1429 93.9683 ENSG00000134001 homo_sapiens ENSP00000256383 97.1429 93.9683 cyprinodon_variegatus ENSCVAP00000021409 97.1429 93.9683 ENSG00000134001 homo_sapiens ENSP00000256383 97.7778 93.3333 denticeps_clupeoides ENSDCDP00000000599 97.7778 93.3333 ENSG00000134001 homo_sapiens ENSP00000256383 97.7778 94.2857 larimichthys_crocea ENSLCRP00005043750 97.7778 94.2857 ENSG00000134001 homo_sapiens ENSP00000256383 97.1429 92.381 takifugu_rubripes ENSTRUP00000046037 97.1429 92.381 ENSG00000134001 homo_sapiens ENSP00000256383 99.0476 97.4603 ficedula_albicollis ENSFALP00000028722 99.0476 97.4603 ENSG00000134001 homo_sapiens ENSP00000256383 96.8254 93.6508 hippocampus_comes ENSHCOP00000003762 96.8254 93.6508 ENSG00000134001 homo_sapiens ENSP00000256383 96.1905 93.3333 cyprinus_carpio_carpio ENSCCRP00000036413 96.1905 93.3333 ENSG00000134001 homo_sapiens ENSP00000256383 96.8254 93.3333 cyprinus_carpio_carpio ENSCCRP00000064192 96.8254 93.3333 ENSG00000134001 homo_sapiens ENSP00000256383 96.1905 92.6984 cyprinus_carpio_carpio ENSCCRP00000150671 96.1905 92.6984 ENSG00000134001 homo_sapiens ENSP00000256383 98.7302 97.1429 coturnix_japonica ENSCJPP00005021606 98.7302 97.1429 ENSG00000134001 homo_sapiens ENSP00000256383 97.1429 94.2857 poecilia_latipinna ENSPLAP00000003800 97.1429 94.2857 ENSG00000134001 homo_sapiens ENSP00000256383 96.8254 93.3333 sinocyclocheilus_grahami ENSSGRP00000104626 96.8254 93.3333 ENSG00000134001 homo_sapiens ENSP00000256383 66.3492 62.8571 sinocyclocheilus_grahami ENSSGRP00000073440 94.5701 89.5928 ENSG00000134001 homo_sapiens ENSP00000256383 96.8254 93.3333 sinocyclocheilus_grahami ENSSGRP00000094739 96.8254 93.3333 ENSG00000134001 homo_sapiens ENSP00000256383 97.1429 93.3333 sinocyclocheilus_grahami ENSSGRP00000027812 97.1429 93.3333 ENSG00000134001 homo_sapiens ENSP00000256383 97.4603 94.2857 maylandia_zebra ENSMZEP00005001845 97.4603 94.2857 ENSG00000134001 homo_sapiens ENSP00000256383 97.7778 93.3333 tetraodon_nigroviridis ENSTNIP00000015189 97.7778 93.3333 ENSG00000134001 homo_sapiens ENSP00000256383 97.1429 93.9683 paramormyrops_kingsleyae ENSPKIP00000024191 97.1429 93.9683 ENSG00000134001 homo_sapiens ENSP00000256383 96.1905 93.0159 scleropages_formosus ENSSFOP00015003717 96.1905 93.0159 ENSG00000134001 homo_sapiens ENSP00000256383 98.7302 95.2381 leptobrachium_leishanense ENSLLEP00000047049 96.8847 93.4579 ENSG00000134001 homo_sapiens ENSP00000256383 97.4603 94.6032 scophthalmus_maximus ENSSMAP00000004154 97.4603 94.6032 ENSG00000134001 homo_sapiens ENSP00000256383 86.3492 83.4921 oryzias_melastigma ENSOMEP00000035725 83.6923 80.9231
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0003723 enables RNA binding 1 HDA Homo_sapiens(9606) Function GO:0003743 enables translation initiation factor activity 2 IBA,IDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005634 located_in nucleus 1 IEA Homo_sapiens(9606) Component GO:0005829 located_in cytosol 2 IDA,TAS Homo_sapiens(9606) Component GO:0005844 part_of polysome 1 TAS Homo_sapiens(9606) Component GO:0005850 part_of eukaryotic translation initiation factor 2 complex 2 IBA,IDA Homo_sapiens(9606) Component GO:0006413 involved_in translational initiation 2 IBA,IDA Homo_sapiens(9606) Process GO:0010494 located_in cytoplasmic stress granule 1 ISS Homo_sapiens(9606) Component GO:0016020 located_in membrane 1 HDA Homo_sapiens(9606) Component GO:0032057 involved_in negative regulation of translational initiation in response to stress 1 ISS Homo_sapiens(9606) Process GO:0033290 part_of eukaryotic 48S preinitiation complex 1 IBA Homo_sapiens(9606) Component GO:0034063 involved_in stress granule assembly 1 ISS Homo_sapiens(9606) Process GO:0034198 involved_in cellular response to amino acid starvation 1 ISS Homo_sapiens(9606) Process GO:0034599 involved_in cellular response to oxidative stress 1 ISS Homo_sapiens(9606) Process GO:0034605 involved_in cellular response to heat 1 IEA Homo_sapiens(9606) Process GO:0034644 involved_in cellular response to UV 1 ISS Homo_sapiens(9606) Process GO:0034976 involved_in response to endoplasmic reticulum stress 3 IDA,IMP,ISS Homo_sapiens(9606) Process GO:0036490 involved_in regulation of translation in response to endoplasmic reticulum stress 1 IMP Homo_sapiens(9606) Process GO:0036499 involved_in PERK-mediated unfolded protein response 2 IDA,NAS Homo_sapiens(9606) Process GO:0043022 enables ribosome binding 2 IBA,IDA Homo_sapiens(9606) Function GO:0043558 involved_in regulation of translational initiation in response to stress 1 IEA Homo_sapiens(9606) Process GO:0044207 part_of translation initiation ternary complex 1 IEA Homo_sapiens(9606) Component GO:0045202 located_in synapse 1 IEA Homo_sapiens(9606) Component GO:0046777 involved_in protein autophosphorylation 1 IEA Homo_sapiens(9606) Process GO:0070062 located_in extracellular exosome 1 HDA Homo_sapiens(9606) Component GO:0097451 located_in glial limiting end-foot 1 IEA Homo_sapiens(9606) Component GO:1901216 involved_in positive regulation of neuron death 1 IEA Homo_sapiens(9606) Process GO:1905098 involved_in negative regulation of guanyl-nucleotide exchange factor activity 1 IEA Homo_sapiens(9606) Process GO:1990737 involved_in response to manganese-induced endoplasmic reticulum stress 1 IEA Homo_sapiens(9606) Process GO:2000676 involved_in positive regulation of type B pancreatic cell apoptotic process 1 IEA Homo_sapiens(9606) Process
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