Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucleP-bodyNucleoli
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000125351 Gene ID 65109 Accession 20439
Symbol UPF3B Alias MRX62;MRX82;UPF3X;HUPF3B;MRXS14;RENT3B;UPF3BP1;UPF3BP2;UPF3BP3;Upf3p-X Full Name UPF3B regulator of nonsense mediated mRNA decay
Status Confidence Length 18977 bases Strand Minus strand
Position X : 119834022 - 119852998 RNA binding domain Smg4_UPF3
Summary This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome X. Two splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000245418 Smg4_UPF3 PF03467 9e-53 1
ENSP00000276201 Smg4_UPF3 PF03467 9e-53 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
35640974 Structures of nonsense-mediated mRNA decay factors UPF3B and UPF3A in complex with UPF2 reveal molecular basis for competitive binding and for neurodevelopmental disorder-causing mutation. C Joshua Bufton 2022-06-10 Nucleic acids research
28899899 Dual function of UPF3B in early and late translation termination. Gabriele Neu-Yilik 2017-10-16 The EMBO journal
29626148 New insights into the interplay between the translation machinery and nonsense-mediated mRNA decay factors. Etienne Raimondeau 2018-06-19 Biochemical Society transactions
29333258 An RNA decay factor wears a new coat: UPF3B modulates translation termination. Zhaofeng Gao 2017-01-01 F1000Research
32213869 Nonsense-Mediated mRNA Decay: Pathologies and the Potential for Novel Therapeutics. Kamila Pawlicka 2020-03-24 Cancers
35551602 No-nonsense: insights into the functional interplay of nonsense-mediated mRNA decay factors. Justine Mailliot 2022-05-13 The Biochemical journal
15004547 The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3. Jan Kadlec 2004-04-01 Nature structural & molecular biology
19478851 The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay. H Niels Gehring 2009-05-26 PLoS biology
27475226 Exon Junction Complexes Show a Distributional Bias toward Alternatively Spliced mRNAs and against mRNAs Coding for Ribosomal Proteins. Christian Hauer 2016-08-09 Cell reports
26012578 Full UPF3B function is critical for neuronal differentiation of neural stem cells. Tahani Alrahbeni 2015-05-27 Molecular brain

Transcripts

Name Transcript ID bp Protein Translation ID
UPF3B-201 ENST00000276201 2343 483aa ENSP00000276201
UPF3B-202 ENST00000345865 2335 470aa ENSP00000245418
UPF3B-203 ENST00000478840 748 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000125351homo_sapiensENSP0000036444863.655545.1681homo_sapiensENSP0000027620162.732944.5135

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000125351homo_sapiensENSP0000027620199.585999.5859nomascus_leucogenysENSNLEP0000001813599.792599.7925
ENSG00000125351homo_sapiensENSP00000276201100100pan_paniscusENSPPAP00000035136100100
ENSG00000125351homo_sapiensENSP0000027620199.79399.793pongo_abeliiENSPPYP0000002314299.79399.793
ENSG00000125351homo_sapiensENSP00000276201100100pan_troglodytesENSPTRP00000038268100100
ENSG00000125351homo_sapiensENSP00000276201100100gorilla_gorillaENSGGOP00000019869100100
ENSG00000125351homo_sapiensENSP0000027620186.749571.8427ornithorhynchus_anatinusENSOANP0000000412487.110272.1414
ENSG00000125351homo_sapiensENSP0000027620185.093269.5652sarcophilus_harrisiiENSSHAP0000000997772.105358.9474
ENSG00000125351homo_sapiensENSP0000027620163.14752.588notamacropus_eugeniiENSMEUP0000001425978.811465.6331
ENSG00000125351homo_sapiensENSP0000027620196.894494.617dasypus_novemcinctusENSDNOP0000000670796.894494.617
ENSG00000125351homo_sapiensENSP0000027620153.830249.4824erinaceus_europaeusENSEEUP0000001258979.510773.0887
ENSG00000125351homo_sapiensENSP0000027620198.757897.9296callithrix_jacchusENSCJAP0000000913998.757897.9296
ENSG00000125351homo_sapiensENSP0000027620199.79399.793cercocebus_atysENSCATP0000000533399.79399.793
ENSG00000125351homo_sapiensENSP0000027620199.585999.5859macaca_fascicularisENSMFAP0000002812599.585999.5859
ENSG00000125351homo_sapiensENSP0000027620199.585999.5859macaca_mulattaENSMMUP0000002662499.585999.5859
ENSG00000125351homo_sapiensENSP0000027620199.585999.5859macaca_nemestrinaENSMNEP0000003305599.585999.5859
ENSG00000125351homo_sapiensENSP0000027620199.79399.793papio_anubisENSPANP0000003048999.79399.793
ENSG00000125351homo_sapiensENSP0000027620199.79399.793mandrillus_leucophaeusENSMLEP0000000267899.79399.793
ENSG00000125351homo_sapiensENSP0000027620192.546690.0621vulpes_vulpesENSVVUP0000001585996.336293.75
ENSG00000125351homo_sapiensENSP0000027620191.718484.6791mus_spretusMGP_SPRETEiJ_P009497493.855986.6525
ENSG00000125351homo_sapiensENSP0000027620198.136696.0663equus_asinusENSEASP0000501874598.340296.2656
ENSG00000125351homo_sapiensENSP0000027620165.838556.9358capra_hircusENSCHIP0000000818879.699268.9223
ENSG00000125351homo_sapiensENSP0000027620197.722695.8592capra_hircusENSCHIP0000000034697.722695.8592
ENSG00000125351homo_sapiensENSP0000027620195.031193.1677capra_hircusENSCHIP0000001868097.245895.339
ENSG00000125351homo_sapiensENSP0000027620193.788890.4762loxodonta_africanaENSLAFP0000000106896.38392.9787
ENSG00000125351homo_sapiensENSP0000027620197.722695.4451panthera_leoENSPLOP0000002791496.919994.6612
ENSG00000125351homo_sapiensENSP0000027620197.929695.8592ailuropoda_melanoleucaENSAMEP0000000018297.929695.8592
ENSG00000125351homo_sapiensENSP0000027620197.515595.6522bos_indicus_hybridENSBIXP0000501421297.515595.6522
ENSG00000125351homo_sapiensENSP0000027620197.722695.0311oryctolagus_cuniculusENSOCUP0000000880197.722695.0311
ENSG00000125351homo_sapiensENSP0000027620198.136696.0663equus_caballusENSECAP0000001464798.340296.2656
ENSG00000125351homo_sapiensENSP0000027620155.072553.2091canis_lupus_familiarisENSCAFP0084503489397.794194.4853
ENSG00000125351homo_sapiensENSP0000027620197.515595.2381panthera_pardusENSPPRP0000000227697.515595.2381
ENSG00000125351homo_sapiensENSP0000027620193.581890.6832marmota_marmota_marmotaENSMMMP0000000744596.170293.1915
ENSG00000125351homo_sapiensENSP0000027620196.273395.0311balaenoptera_musculusENSBMSP0001002967796.273395.0311
ENSG00000125351homo_sapiensENSP0000027620197.515595.2381felis_catusENSFCAP0000002741697.113494.8454
ENSG00000125351homo_sapiensENSP0000027620192.132589.8551ursus_americanusENSUAMP0000003213095.289192.9336
ENSG00000125351homo_sapiensENSP0000027620179.08965.6315monodelphis_domesticaENSMODP0000003818687.614772.7064
ENSG00000125351homo_sapiensENSP0000027620193.374792.1325monodon_monocerosENSMMNP0001502357993.958392.7083
ENSG00000125351homo_sapiensENSP0000027620196.894495.0311sus_scrofaENSSSCP0000001341596.894495.0311
ENSG00000125351homo_sapiensENSP0000027620165.217463.9752microcebus_murinusENSMICP0000000158698.746196.8652
ENSG00000125351homo_sapiensENSP0000027620188.819985.3002octodon_degusENSODEP0000000284793.668189.9563
ENSG00000125351homo_sapiensENSP0000027620138.923437.4741octodon_degusENSODEP0000000958187.850584.5794
ENSG00000125351homo_sapiensENSP0000027620193.995988.6128jaculus_jaculusENSJJAP0000000003096.186490.678
ENSG00000125351homo_sapiensENSP0000027620185.093283.2298ursus_maritimusENSUMAP0000000241589.347887.3913
ENSG00000125351homo_sapiensENSP0000027620154.865452.1739ochotona_princepsENSOPRP0000000707754.865452.1739
ENSG00000125351homo_sapiensENSP0000027620193.788892.3395delphinapterus_leucasENSDLEP0000002661492.827991.3934
ENSG00000125351homo_sapiensENSP0000027620195.652293.7888physeter_catodonENSPCTP0000502999294.285792.449
ENSG00000125351homo_sapiensENSP0000027620191.718484.8861mus_caroliMGP_CAROLIEiJ_P009122393.855986.8644
ENSG00000125351homo_sapiensENSP0000027620191.718484.6791mus_musculusENSMUSP0000007561493.855986.6525
ENSG00000125351homo_sapiensENSP0000027620192.132585.5072dipodomys_ordiiENSDORP0000000569095.289188.4368
ENSG00000125351homo_sapiensENSP0000027620192.132590.0621mustela_putorius_furoENSMPUP0000000151697.374295.186
ENSG00000125351homo_sapiensENSP0000027620192.546690.6832aotus_nancymaaeENSANAP0000001543097.385695.4248
ENSG00000125351homo_sapiensENSP0000027620148.861347.412aotus_nancymaaeENSANAP0000003085194.779191.9679
ENSG00000125351homo_sapiensENSP0000027620198.550797.9296aotus_nancymaaeENSANAP0000000774898.550797.9296
ENSG00000125351homo_sapiensENSP0000027620198.757897.7226saimiri_boliviensis_boliviensisENSSBOP0000000574298.757897.7226
ENSG00000125351homo_sapiensENSP0000027620182.815781.1594vicugna_pacosENSVPAP0000000928097.56195.6098
ENSG00000125351homo_sapiensENSP00000276201100100chlorocebus_sabaeusENSCSAP00000014356100100
ENSG00000125351homo_sapiensENSP0000027620181.366579.089tupaia_belangeriENSTBEP0000000279381.366579.089
ENSG00000125351homo_sapiensENSP0000027620193.995986.5424mesocricetus_auratusENSMAUP0000000688494.190986.722
ENSG00000125351homo_sapiensENSP0000027620195.652294.4099phocoena_sinusENSPSNP0000002272595.652294.4099
ENSG00000125351homo_sapiensENSP0000027620197.515595.6522camelus_dromedariusENSCDRP0000501917797.515595.6522
ENSG00000125351homo_sapiensENSP0000027620194.409992.7536carlito_syrichtaENSTSYP0000002270397.435995.7265
ENSG00000125351homo_sapiensENSP0000027620197.308595.0311panthera_tigris_altaicaENSPTIP0000001653494.567492.3541
ENSG00000125351homo_sapiensENSP0000027620195.031187.7847rattus_norvegicusENSRNOP0000007575894.639287.4227
ENSG00000125351homo_sapiensENSP0000027620198.550796.2733prolemur_simusENSPSMP0000000017898.347196.0744
ENSG00000125351homo_sapiensENSP0000027620195.031188.1988microtus_ochrogasterENSMOCP0000002012195.031188.1988
ENSG00000125351homo_sapiensENSP0000027620183.022876.3975sorex_araneusENSSARP0000000375792.824185.4167
ENSG00000125351homo_sapiensENSP0000027620193.581886.5424peromyscus_maniculatus_bairdiiENSPEMP0000001183395.560388.3721
ENSG00000125351homo_sapiensENSP0000027620197.515595.6522bos_mutusENSBMUP0000001382897.515595.6522
ENSG00000125351homo_sapiensENSP0000027620139.130436.0248mus_spicilegusENSMSIP0000000853794.587
ENSG00000125351homo_sapiensENSP0000027620170.807563.9752cricetulus_griseus_chok1gshdENSCGRP0000101216192.934883.9674
ENSG00000125351homo_sapiensENSP0000027620192.132583.2298cricetulus_griseus_chok1gshdENSCGRP0000100524994.680985.5319
ENSG00000125351homo_sapiensENSP0000027620183.850981.5735pteropus_vampyrusENSPVAP0000001327284.199681.9127
ENSG00000125351homo_sapiensENSP0000027620194.409991.9255myotis_lucifugusENSMLUP0000000987597.021394.4681
ENSG00000125351homo_sapiensENSP0000027620184.886169.5652vombatus_ursinusENSVURP0001001949972.183159.1549
ENSG00000125351homo_sapiensENSP0000027620134.161529.3996rhinolophus_ferrumequinumENSRFEP0001001404479.710168.599
ENSG00000125351homo_sapiensENSP0000027620197.722695.8592neovison_visonENSNVIP0000002906097.722695.8592
ENSG00000125351homo_sapiensENSP0000027620162.318861.6977bos_taurusENSBTAP0000002779298.045697.0684
ENSG00000125351homo_sapiensENSP0000027620142.02940.1656heterocephalus_glaber_femaleENSHGLP0000001565086.752182.906
ENSG00000125351homo_sapiensENSP0000027620180.952480.1242rhinopithecus_bietiENSRBIP0000002670798.737497.7273
ENSG00000125351homo_sapiensENSP0000027620192.546690.0621canis_lupus_dingoENSCAFP0002000497796.336293.75
ENSG00000125351homo_sapiensENSP0000027620195.859292.9607sciurus_vulgarisENSSVLP0000501858795.859292.9607
ENSG00000125351homo_sapiensENSP0000027620182.608767.7019phascolarctos_cinereusENSPCIP0000003938186.55170.9328
ENSG00000125351homo_sapiensENSP0000027620195.859292.5466procavia_capensisENSPCAP0000000881995.859292.5466
ENSG00000125351homo_sapiensENSP0000027620192.132584.265nannospalax_galiliENSNGAP0000000572294.279786.2288
ENSG00000125351homo_sapiensENSP0000027620197.308595.4451bos_grunniensENSBGRP0000003152997.510495.6432
ENSG00000125351homo_sapiensENSP0000027620193.788889.441chinchilla_lanigeraENSCLAP0000000458096.38391.9149
ENSG00000125351homo_sapiensENSP0000027620197.722695.8592cervus_hanglu_yarkandensisENSCHYP0000002013197.722695.8592
ENSG00000125351homo_sapiensENSP0000027620196.894494.617catagonus_wagneriENSCWAP0000000170097.095494.8133
ENSG00000125351homo_sapiensENSP0000027620193.167790.2691ictidomys_tridecemlineatusENSSTOP0000000098095.744792.766
ENSG00000125351homo_sapiensENSP0000027620187.163678.0538otolemur_garnettiiENSOGAP0000002047091.521781.9565
ENSG00000125351homo_sapiensENSP0000027620195.445192.5466otolemur_garnettiiENSOGAP0000000414898.085195.1064
ENSG00000125351homo_sapiensENSP0000027620164.182260.4555cebus_imitatorENSCCAP0000002405682.228177.4536
ENSG00000125351homo_sapiensENSP0000027620193.374790.4762urocitellus_parryiiENSUPAP0001000182995.957492.9787
ENSG00000125351homo_sapiensENSP0000027620197.515595.6522moschus_moschiferusENSMMSP0000000650297.515595.6522
ENSG00000125351homo_sapiensENSP0000027620129.606627.7433moschus_moschiferusENSMMSP0000000273069.082164.7343
ENSG00000125351homo_sapiensENSP00000276201100100rhinopithecus_roxellanaENSRROP00000035009100100
ENSG00000125351homo_sapiensENSP0000027620191.511484.058mus_pahariMGP_PahariEiJ_P008886693.644186.017
ENSG00000125351homo_sapiensENSP0000027620198.136696.0663propithecus_coquereliENSPCOP0000002000797.933995.8678
ENSG00000125351homo_sapiensENSP0000027620134.989619.8758caenorhabditis_elegansF46B6.3b.145.923926.087
ENSG00000125351homo_sapiensENSP0000027620145.341628.5714drosophila_melanogasterFBpp007213044.512228.0488
ENSG00000125351homo_sapiensENSP0000027620127.743318.8406ciona_intestinalisENSCINP0000001712468.020346.1929
ENSG00000125351homo_sapiensENSP0000027620151.759835.6108eptatretus_burgeriENSEBUP0000002202851.546435.4639
ENSG00000125351homo_sapiensENSP0000027620122.774318.4265callorhinchus_miliiENSCMIP0000003369153.658543.4146
ENSG00000125351homo_sapiensENSP0000027620176.811660.6625latimeria_chalumnaeENSLACP0000000985678.936262.3404
ENSG00000125351homo_sapiensENSP0000027620172.463854.0373lepisosteus_oculatusENSLOCP0000001875177.433657.7434
ENSG00000125351homo_sapiensENSP0000027620176.397554.4513clupea_harengusENSCHAP0000004506480.043457.0499
ENSG00000125351homo_sapiensENSP0000027620172.049754.8654danio_rerioENSDARP0000001194874.518256.7452
ENSG00000125351homo_sapiensENSP0000027620170.807551.7598carassius_auratusENSCARP0000012914574.02654.1126
ENSG00000125351homo_sapiensENSP0000027620171.428653.0021carassius_auratusENSCARP0000001366374.51455.2916
ENSG00000125351homo_sapiensENSP0000027620171.428652.795carassius_auratusENSCARP0000003444674.675355.1948
ENSG00000125351homo_sapiensENSP0000027620151.138739.7516astyanax_mexicanusENSAMXP0000000020584.300365.529
ENSG00000125351homo_sapiensENSP0000027620175.362355.2795ictalurus_punctatusENSIPUP0000002845478.617757.6674
ENSG00000125351homo_sapiensENSP0000027620175.569454.4513esox_luciusENSELUP0000002127175.413254.3388
ENSG00000125351homo_sapiensENSP0000027620174.327155.2795electrophorus_electricusENSEEEP0000003021875.262155.9748
ENSG00000125351homo_sapiensENSP0000027620171.635651.1387oncorhynchus_kisutchENSOKIP0000507298876.548754.646
ENSG00000125351homo_sapiensENSP0000027620174.948253.6232oncorhynchus_kisutchENSOKIP0000506305375.416753.9583
ENSG00000125351homo_sapiensENSP0000027620174.120153.2091oncorhynchus_mykissENSOMYP0000004548470.891150.8911
ENSG00000125351homo_sapiensENSP0000027620171.842750.9317oncorhynchus_mykissENSOMYP0000010366676.769954.4248
ENSG00000125351homo_sapiensENSP0000027620172.463850.7246salmo_salarENSSSAP0000010126176.754453.7281
ENSG00000125351homo_sapiensENSP0000027620174.741253.4161salmo_salarENSSSAP0000000444975.365353.8622
ENSG00000125351homo_sapiensENSP0000027620174.327152.795salmo_truttaENSSTUP0000004556562.434844.3478
ENSG00000125351homo_sapiensENSP0000027620172.256750.7246salmo_truttaENSSTUP0000000413376.535153.7281
ENSG00000125351homo_sapiensENSP0000027620172.877851.9669gadus_morhuaENSGMOP0000003612469.841349.8016
ENSG00000125351homo_sapiensENSP0000027620173.291952.1739fundulus_heteroclitusENSFHEP0000003179177.124254.902
ENSG00000125351homo_sapiensENSP0000027620127.122221.9462poecilia_reticulataENSPREP0000001806287.919571.1409
ENSG00000125351homo_sapiensENSP0000027620173.91353.2091xiphophorus_maculatusENSXMAP0000001371178.807956.7329
ENSG00000125351homo_sapiensENSP0000027620174.534253.0021oryzias_latipesENSORLP0000000126778.774656.0175
ENSG00000125351homo_sapiensENSP0000027620166.045546.7909cyclopterus_lumpusENSCLMP0000500942474.35952.6807
ENSG00000125351homo_sapiensENSP0000027620175.155356.1077oreochromis_niloticusENSONIP0000000317578.232858.4052
ENSG00000125351homo_sapiensENSP0000027620170.600451.9669haplochromis_burtoniENSHBUP0000001549070.309351.7526
ENSG00000125351homo_sapiensENSP0000027620174.534254.6584astatotilapia_callipteraENSACLP0000000237478.431457.5163
ENSG00000125351homo_sapiensENSP0000027620171.428651.5528sparus_aurataENSSAUP0001004341563.419145.7721
ENSG00000125351homo_sapiensENSP0000027620126.915121.118lates_calcariferENSLCAP0001003139776.023459.6491
ENSG00000125351homo_sapiensENSP0000027620175.569455.2795lates_calcariferENSLCAP0001005388578.833757.6674
ENSG00000125351homo_sapiensENSP0000027620173.49954.4513xenopus_tropicalisENSXETP0000001620074.736855.3684
ENSG00000125351homo_sapiensENSP0000027620178.88264.5963chrysemys_picta_belliiENSCPBP0000002935383.369868.2713
ENSG00000125351homo_sapiensENSP0000027620179.503165.6315sphenodon_punctatusENSSPUP0000001692980.842166.7368
ENSG00000125351homo_sapiensENSP0000027620179.710164.5963crocodylus_porosusENSCPRP0000500825479.710164.5963
ENSG00000125351homo_sapiensENSP0000027620166.045553.8302laticauda_laticaudataENSLLTP0000001296379.7565
ENSG00000125351homo_sapiensENSP0000027620181.573565.4244notechis_scutatusENSNSUP0000001341881.742765.5602
ENSG00000125351homo_sapiensENSP0000027620182.194665.8385pseudonaja_textilisENSPTXP0000002756882.365165.9751
ENSG00000125351homo_sapiensENSP0000027620170.393455.9006gallus_gallusENSGALP0001001804956.856245.1505
ENSG00000125351homo_sapiensENSP0000027620177.846863.147meleagris_gallopavoENSMGAP0000000788467.625954.8561
ENSG00000125351homo_sapiensENSP0000027620182.815767.0807serinus_canariaENSSCAP0000002370182.987567.2199
ENSG00000125351homo_sapiensENSP0000027620135.196729.3996parus_majorENSPMJP0000001499381.730868.2692
ENSG00000125351homo_sapiensENSP0000027620181.573566.0455anolis_carolinensisENSACAP0000000357084.731268.6021
ENSG00000125351homo_sapiensENSP0000027620134.782627.1222neolamprologus_brichardiENSNBRP0000001497081.553463.5922
ENSG00000125351homo_sapiensENSP0000027620117.805414.2857naja_najaENSNNAP0000001507364.179151.4925
ENSG00000125351homo_sapiensENSP0000027620184.05867.7019podarcis_muralisENSPMRP0000003040275.324760.6679
ENSG00000125351homo_sapiensENSP0000027620133.333327.3292geospiza_fortisENSGFOP0000002128482.564167.6923
ENSG00000125351homo_sapiensENSP0000027620166.666753.8302taeniopygia_guttataENSTGUP0000000352978.921663.7255
ENSG00000125351homo_sapiensENSP0000027620174.120154.8654erpetoichthys_calabaricusENSECRP0000002151078.854658.37
ENSG00000125351homo_sapiensENSP0000027620174.741254.0373kryptolebias_marmoratusENSKMAP0000002737479.166757.2368
ENSG00000125351homo_sapiensENSP0000027620172.463858.7992salvator_merianaeENSSMRP0000002290281.395366.0465
ENSG00000125351homo_sapiensENSP0000027620174.534253.4161oryzias_javanicusENSOJAP0000003810178.774656.4551
ENSG00000125351homo_sapiensENSP0000027620172.877854.4513amphilophus_citrinellusENSACIP0000001743877.53357.9295
ENSG00000125351homo_sapiensENSP0000027620174.741252.381dicentrarchus_labraxENSDLAP0000503585575.208352.7083
ENSG00000125351homo_sapiensENSP0000027620174.948255.4865amphiprion_perculaENSAPEP0000000772479.212358.6433
ENSG00000125351homo_sapiensENSP0000027620174.327152.795oryzias_sinensisENSOSIP0000000602878.901156.044
ENSG00000125351homo_sapiensENSP0000027620151.552841.6149pelodiscus_sinensisENSPSIP0000000629588.297971.2766
ENSG00000125351homo_sapiensENSP0000027620179.296164.5963gopherus_evgoodeiENSGEVP0000501502782.365667.0968
ENSG00000125351homo_sapiensENSP0000027620179.503164.5963chelonoidis_abingdoniiENSCABP0000002374282.580667.0968
ENSG00000125351homo_sapiensENSP0000027620175.362353.4161seriola_dumeriliENSSDUP0000000774378.958855.9653
ENSG00000125351homo_sapiensENSP0000027620174.948251.5528cottoperca_gobioENSCGOP0000003548470.291348.3495
ENSG00000125351homo_sapiensENSP0000027620169.979356.5217struthio_camelus_australisENSSCUP0000000869084.079667.9104
ENSG00000125351homo_sapiensENSP0000027620182.815767.9089anser_brachyrhynchusENSABRP0000000312883.160168.1913
ENSG00000125351homo_sapiensENSP0000027620174.327153.8302gasterosteus_aculeatusENSGACP0000002304277.705656.2771
ENSG00000125351homo_sapiensENSP0000027620173.49953.4161cynoglossus_semilaevisENSCSEP0000000311874.579854.2017
ENSG00000125351homo_sapiensENSP0000027620174.534254.0373poecilia_formosaENSPFOP0000001750779.470257.6159
ENSG00000125351homo_sapiensENSP0000027620174.327153.8302poecilia_formosaENSPFOP0000000631079.249557.3951
ENSG00000125351homo_sapiensENSP0000027620175.776456.3147myripristis_murdjanENSMMDP0000503301777.872357.8723
ENSG00000125351homo_sapiensENSP0000027620175.569453.2091sander_luciopercaENSSLUP0000004938378.494655.2688
ENSG00000125351homo_sapiensENSP0000027620180.745365.6315strigops_habroptilaENSSHBP0000501728981.5966.318
ENSG00000125351homo_sapiensENSP0000027620173.49954.0373amphiprion_ocellarisENSAOCP0000002438178.539857.7434
ENSG00000125351homo_sapiensENSP0000027620179.08963.9752terrapene_carolina_triunguisENSTMTP0000000923382.68466.8831
ENSG00000125351homo_sapiensENSP0000027620174.948253.4161hucho_huchoENSHHUP0000004514175.416753.75
ENSG00000125351homo_sapiensENSP0000027620175.362355.2795betta_splendensENSBSLP0000005126378.787957.7922
ENSG00000125351homo_sapiensENSP0000027620175.155355.2795pygocentrus_nattereriENSPNAP0000001547078.401757.6674
ENSG00000125351homo_sapiensENSP0000027620175.983455.2795anabas_testudineusENSATEP0000002709079.265757.6674
ENSG00000125351homo_sapiensENSP0000027620146.997928.5714ciona_savignyiENSCSAVP0000001510152.546331.9444
ENSG00000125351homo_sapiensENSP0000027620175.569453.6232seriola_lalandi_dorsalisENSSLDP0000000393979.175756.1822
ENSG00000125351homo_sapiensENSP0000027620161.076643.8923labrus_bergyltaENSLBEP0000003847564.69346.4912
ENSG00000125351homo_sapiensENSP0000027620174.534254.4513pundamilia_nyerereiENSPNYP0000001298078.774657.5492
ENSG00000125351homo_sapiensENSP0000027620176.190555.2795mastacembelus_armatusENSMAMP0000002978075.255654.6012
ENSG00000125351homo_sapiensENSP0000027620174.327153.8302stegastes_partitusENSSPAP0000001319078.555856.8928
ENSG00000125351homo_sapiensENSP0000027620171.842751.3458oncorhynchus_tshawytschaENSOTSP0000500567776.940154.9889
ENSG00000125351homo_sapiensENSP0000027620164.803346.5839oncorhynchus_tshawytschaENSOTSP0000506233771.298451.2528
ENSG00000125351homo_sapiensENSP0000027620174.327155.2795acanthochromis_polyacanthusENSAPOP0000001035178.555858.4245
ENSG00000125351homo_sapiensENSP0000027620176.190560.2484aquila_chrysaetos_chrysaetosENSACCP0002001457677.148861.0063
ENSG00000125351homo_sapiensENSP0000027620173.49953.4161nothobranchius_furzeriENSNFUP0001500027179.596457.8475
ENSG00000125351homo_sapiensENSP0000027620173.70652.588cyprinodon_variegatusENSCVAP0000000378178.241855.8242
ENSG00000125351homo_sapiensENSP0000027620173.91354.4513denticeps_clupeoidesENSDCDP0000005074676.774256.5591
ENSG00000125351homo_sapiensENSP0000027620175.362354.4513larimichthys_croceaENSLCRP0000504707478.279656.5591
ENSG00000125351homo_sapiensENSP0000027620173.70652.588takifugu_rubripesENSTRUP0000002687278.761156.1947
ENSG00000125351homo_sapiensENSP0000027620180.124264.8033ficedula_albicollisENSFALP0000000163680.962365.4812
ENSG00000125351homo_sapiensENSP0000027620172.049753.8302hippocampus_comesENSHCOP0000001378475.982556.7686
ENSG00000125351homo_sapiensENSP0000027620171.221552.1739cyprinus_carpio_carpioENSCCRP0000000296674.458954.5455
ENSG00000125351homo_sapiensENSP0000027620171.014553.6232cyprinus_carpio_carpioENSCCRP0000012150574.242456.0606
ENSG00000125351homo_sapiensENSP0000027620166.873753.2091coturnix_japonicaENSCJPP0000502380179.361263.145
ENSG00000125351homo_sapiensENSP0000027620174.741254.4513poecilia_latipinnaENSPLAP0000000357679.690958.0574
ENSG00000125351homo_sapiensENSP0000027620174.741254.4513poecilia_latipinnaENSPLAP0000001590379.690958.0574
ENSG00000125351homo_sapiensENSP0000027620170.600453.2091sinocyclocheilus_grahamiENSSGRP0000011009174.291955.9913
ENSG00000125351homo_sapiensENSP0000027620120.703916.7702sinocyclocheilus_grahamiENSSGRP0000001116684.033668.0672
ENSG00000125351homo_sapiensENSP0000027620174.534254.8654maylandia_zebraENSMZEP0000501043378.431457.7342
ENSG00000125351homo_sapiensENSP0000027620167.494850.3106tetraodon_nigroviridisENSTNIP0000001883976.886857.3113
ENSG00000125351homo_sapiensENSP0000027620172.049753.4161paramormyrops_kingsleyaeENSPKIP0000000083675.982556.3319
ENSG00000125351homo_sapiensENSP0000027620175.155356.5217scleropages_formosusENSSFOP0001500858780.132560.2649
ENSG00000125351homo_sapiensENSP0000027620173.291954.4513leptobrachium_leishanenseENSLLEP0000002115476.789657.0499
ENSG00000125351homo_sapiensENSP0000027620175.362352.588scophthalmus_maximusENSSMAP0000002108278.111654.5064
ENSG00000125351homo_sapiensENSP0000027620174.534253.2091oryzias_melastigmaENSOMEP0000001329078.774656.2363

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000184involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay4IBA,IDA,IMP,NASHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003729enables mRNA binding2IBA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1NASHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005730is_active_in nucleolus2IBA,IDAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm2IBA,NASHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0007420involved_in brain development1IEAHomo_sapiens(9606)Process
GO:0031175involved_in neuron projection development1IEAHomo_sapiens(9606)Process
GO:0034451located_in centriolar satellite1IDAHomo_sapiens(9606)Component
GO:0035145part_of exon-exon junction complex1IDAHomo_sapiens(9606)Component
GO:0043025located_in neuronal cell body1IEAHomo_sapiens(9606)Component
GO:0045666involved_in positive regulation of neuron differentiation1IEAHomo_sapiens(9606)Process
GO:0045727involved_in positive regulation of translation2IBA,IDAHomo_sapiens(9606)Process
GO:0051028involved_in mRNA transport1IEAHomo_sapiens(9606)Process

Expression