Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerFlavivirusesSARS-COV-2DengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq DataSet_01_305 DataSet_01_442

Description

Ensembl ID ENSG00000124214 Gene ID 6780 Accession 11370
Symbol STAU1 Alias STAU;PPP1R150 Full Name staufen double-stranded RNA binding protein 1
Status Confidence Length 75029 bases Strand Minus strand
Position 20 : 49113339 - 49188367 RNA binding domain dsrm , Staufen_C
Summary Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. [provided by RefSeq, Apr 2020]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000360867 Staufen_C PF16482 5.4e-57 1
ENSP00000360867 dsrm PF00035 1.9e-30 2
ENSP00000360867 dsrm PF00035 1.9e-30 3
ENSP00000360867 dsrm PF00035 1.9e-30 4
ENSP00000360893 Staufen_C PF16482 5.4e-57 1
ENSP00000360893 dsrm PF00035 1.9e-30 2
ENSP00000360893 dsrm PF00035 1.9e-30 3
ENSP00000360893 dsrm PF00035 1.9e-30 4
ENSP00000323443 Staufen_C PF16482 6.4e-57 1
ENSP00000323443 dsrm PF00035 9.1e-34 2
ENSP00000323443 dsrm PF00035 9.1e-34 3
ENSP00000323443 dsrm PF00035 9.1e-34 4
ENSP00000345425 Staufen_C PF16482 6.4e-57 1
ENSP00000345425 dsrm PF00035 9.1e-34 2
ENSP00000345425 dsrm PF00035 9.1e-34 3
ENSP00000345425 dsrm PF00035 9.1e-34 4
ENSP00000353604 Staufen_C PF16482 6.4e-57 1
ENSP00000353604 dsrm PF00035 9.1e-34 2
ENSP00000353604 dsrm PF00035 9.1e-34 3
ENSP00000353604 dsrm PF00035 9.1e-34 4
ENSP00000360857 Staufen_C PF16482 6.4e-57 1
ENSP00000360857 dsrm PF00035 8.9e-34 2
ENSP00000360857 dsrm PF00035 8.9e-34 3
ENSP00000360857 dsrm PF00035 8.9e-34 4
ENSP00000360922 Staufen_C PF16482 9.5e-57 1
ENSP00000360922 dsrm PF00035 1.7e-33 2
ENSP00000360922 dsrm PF00035 1.7e-33 3
ENSP00000360922 dsrm PF00035 1.7e-33 4
ENSP00000416779 dsrm PF00035 7.3e-17 1
ENSP00000416779 dsrm PF00035 7.3e-17 2
ENSP00000398785 dsrm PF00035 1.2e-05 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
37517320 Aberrant hyper-expression of the RNA binding protein GIGYF2 in endothelial cells modulates vascular aging and function. Fanglin Niu 2023-09-01 Redox biology
36151701 Staufen Impairs Autophagy in Neurodegeneration. Sharan Paul 2023-02-01 Annals of neurology
34452292 Function of Host Protein Staufen1 in Rabies Virus Replication. Gaowen Liu 2021-07-22 Viruses
22503102 Staufen1-mediated mRNA decay functions in adipogenesis. Hana Cho 2012-05-25 Molecular cell
15166236 The brain-specific double-stranded RNA-binding protein Staufen2: nucleolar accumulation and isoform-specific exportin-5-dependent export. Paolo Macchi 2004-07-23 The Journal of biological chemistry
33499355 Return of the Neurotropic Enteroviruses: Co-Opting Cellular Pathways for Infection. E Christine Peters 2021-01-22 Viruses
33000283 STAU1 selectively regulates the expression of inflammatory and immune response genes and alternative splicing of the nerve growth factor receptor signaling pathway. Yi Zhong 2020-11-01 Oncology reports
31699982 Insights into the assembly and architecture of a Staufen-mediated mRNA decay (SMD)-competent mRNP. Manjeera Gowravaram 2019-11-07 Nature communications
26824521 Staufen1 Regulates Multiple Alternative Splicing Events either Positively or Negatively in DM1 Indicating Its Role as a Disease Modifier. Emma Bondy-Chorney 2016-01-01 PLoS genetics
35939694 dsRNA-induced condensation of antiviral proteins modulates PKR activity. A Giulia Corbet 2022-08-16 Proceedings of the National Academy of Sciences of the United States of America
21508097 Staufen 2 regulates mGluR long-term depression and Map1b mRNA distribution in hippocampal neurons. Geneviève Lebeau 2011-01-01 Learning & memory (Cold Spring Harbor, N.Y.)
31052302 Non-Coding RNA Networks in ALK-Positive Anaplastic-Large Cell Lymphoma. Steffen Fuchs 2019-04-30 International journal of molecular sciences
28004750 SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization. Djodji Nkerorema Damas 2016-12-22 Nature communications
16186820 CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells. Nao Hosoda 2005-10-01 Nature structural & molecular biology
30886404 RNA structure maps across mammalian cellular compartments. Lei Sun 2019-04-01 Nature structural & molecular biology
22096659 The emergence of lncRNAs in cancer biology. R John Prensner 2011-10-01 Cancer discovery
26656492 A novel role for CARM1 in promoting nonsense-mediated mRNA decay: potential implications for spinal muscular atrophy. Gabriel Sanchez 2016-04-07 Nucleic acids research
30026873 Angio-LncRs: LncRNAs that regulate angiogenesis and vascular disease. Bo Yu 2018-01-01 Theranostics
29129909 RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure. Oz Solomon 2017-11-13 Nature communications
28569791 E2F1 induces TINCR transcriptional activity and accelerates gastric cancer progression via activation of TINCR/STAU1/CDKN2B signaling axis. Tong-Peng Xu 2017-06-01 Cell death & disease
25250334 Novel RNA markers in prostate cancer: functional considerations and clinical translation. A M Julia Pickl 2014-01-01 BioMed research international
34660304 The Non-Coding RNAs Inducing Drug Resistance in Ovarian Cancer: A New Perspective for Understanding Drug Resistance. Gaofeng Li 2021-01-01 Frontiers in oncology
32335035 Staufen1 is Essential for Cell-Cycle Transitions and Cell Proliferation Via the Control of E2F1 Expression. Mehdi Ghram 2020-06-12 Journal of molecular biology
37013995 A computationally-enhanced hiCLIP atlas reveals Staufen1-RNA binding features and links 3' UTR structure to RNA metabolism. M Anob Chakrabarti 2023-05-08 Nucleic acids research
23887658 Long non-coding RNAs in haematological malignancies. Andoni Garitano-Trojaola 2013-07-24 International journal of molecular sciences
34670194 Differential expression of long non-coding RNAs as diagnostic markers for lung cancer and other malignant tumors. Li Li 2021-10-20 Aging
35597813 Noncoding RNA actions through IGFs and IGF binding proteins in cancer. Aidan Kerr 2022-06-01 Oncogene
30301857 Staufen1 Interacts with Multiple Components of the Ebola Virus Ribonucleoprotein and Enhances Viral RNA Synthesis. Jingru Fang 2018-10-09 mBio
25799984 hiCLIP reveals the in vivo atlas of mRNA secondary structures recognized by Staufen 1. Yoichiro Sugimoto 2015-03-26 Nature
30744035 Staufen1 Protein Participates Positively in the Viral RNA Replication of Enterovirus 71. Young-Mao Chen 2019-02-08 Viruses
27644878 Hypoxia and ER stress promote Staufen1 expression through an alternative translation mechanism. Florence Bonnet-Magnaval 2016-10-14 Biochemical and biophysical research communications
27695661 Staufen1s role as a splicing factor and a disease modifier in Myotonic Dystrophy Type I. Emma Bondy-Chorney 2016-01-01 Rare diseases (Austin, Tex.)
30781588 Long Non-Coding RNAs in the Regulation of Gene Expression: Physiology and Disease. R C Juliane Fernandes 2019-02-17 Non-coding RNA
34633481 The multifunctional RNA-binding protein Staufen1: an emerging regulator of oncogenesis through its various roles in key cellular events. Shekoufeh Almasi 2021-12-01 Cellular and molecular life sciences : CMLS
31852734 A multipronged approach to understanding the form and function of hStaufen protein. Silvia Visentin 2020-03-01 RNA (New York, N.Y.)

Transcripts

Name Transcript ID bp Protein Translation ID
STAU1-207 ENST00000371856 3651 577aa ENSP00000360922
STAU1-206 ENST00000371828 3411 502aa ENSP00000360893
STAU1-201 ENST00000340954 3334 496aa ENSP00000345425
STAU1-202 ENST00000347458 3136 496aa ENSP00000323443
STAU1-203 ENST00000360426 3211 496aa ENSP00000353604
STAU1-204 ENST00000371792 3130 494aa ENSP00000360857
STAU1-205 ENST00000371802 3154 502aa ENSP00000360867
STAU1-208 ENST00000437404 1085 199aa ENSP00000416779
STAU1-209 ENST00000456866 643 129aa ENSP00000398785

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
103683Body Height2E-2425282103

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000124214homo_sapiensENSP0000046818110.69045.902homo_sapiensENSP0000036092216.63789.18544
ENSG00000124214homo_sapiensENSP0000045750121.713110.757homo_sapiensENSP0000036092218.89089.35875
ENSG00000124214homo_sapiensENSP0000026506913.12856.6108homo_sapiensENSP0000036092224.436712.305
ENSG00000124214homo_sapiensENSP0000032134714.73218.48214homo_sapiensENSP0000036092217.15779.87868
ENSG00000124214homo_sapiensENSP0000035501122.051310.7692homo_sapiensENSP0000036092214.90477.27903
ENSG00000124214homo_sapiensENSP0000001587719.258210.9843homo_sapiensENSP0000036092223.396913.3449
ENSG00000124214homo_sapiensENSP0000026296114.90956.92226homo_sapiensENSP0000036092224.263411.2652
ENSG00000124214homo_sapiensENSP0000032515319.21110.4631homo_sapiensENSP0000036092219.410710.5719
ENSG00000124214homo_sapiensENSP0000029651319.965311.6319homo_sapiensENSP0000036092219.930711.6118
ENSG00000124214homo_sapiensENSP0000037071320.162410.8254homo_sapiensENSP0000036092225.823213.8648
ENSG00000124214homo_sapiensENSP0000031817625.239613.099homo_sapiensENSP0000036092213.69157.10572
ENSG00000124214homo_sapiensENSP0000042875652.456142.4561homo_sapiensENSP0000036092251.819841.9411
ENSG00000124214homo_sapiensENSP0000035745912.9696.93312homo_sapiensENSP0000036092227.556314.7314
ENSG00000124214homo_sapiensENSP0000026698724.590213.9344homo_sapiensENSP0000036092215.59798.83882

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000124214homo_sapiensENSP0000036092299.480199.3068nomascus_leucogenysENSNLEP0000000848299.480199.3068
ENSG00000124214homo_sapiensENSP0000036092296.707195.3206pan_paniscusENSPPAP0000001794595.384694.0171
ENSG00000124214homo_sapiensENSP0000036092299.480199.3068pongo_abeliiENSPPYP0000001241699.652899.4792
ENSG00000124214homo_sapiensENSP0000036092296.707195.3206pan_troglodytesENSPTRP0000009356095.384694.0171
ENSG00000124214homo_sapiensENSP0000036092296.707195.1473gorilla_gorillaENSGGOP0000002541195.384693.8462
ENSG00000124214homo_sapiensENSP0000036092294.800789.6014ornithorhynchus_anatinusENSOANP0000001020778.031473.7518
ENSG00000124214homo_sapiensENSP0000036092296.533893.0676sarcophilus_harrisiiENSSHAP0000002776082.518579.5556
ENSG00000124214homo_sapiensENSP0000036092288.561585.7886notamacropus_eugeniiENSMEUP0000000297588.869686.087
ENSG00000124214homo_sapiensENSP0000036092298.786897.4003choloepus_hoffmanniENSCHOP0000000133898.615997.2318
ENSG00000124214homo_sapiensENSP0000036092299.306898.0936dasypus_novemcinctusENSDNOP0000001157796.790595.6081
ENSG00000124214homo_sapiensENSP0000036092279.029577.123erinaceus_europaeusENSEEUP0000001310079.029577.123
ENSG00000124214homo_sapiensENSP0000036092284.402182.669echinops_telfairiENSETEP0000001481284.402182.669
ENSG00000124214homo_sapiensENSP0000036092298.786898.6135callithrix_jacchusENSCJAP0000002998296.938896.7687
ENSG00000124214homo_sapiensENSP0000036092299.480199.4801cercocebus_atysENSCATP0000000934699.480199.4801
ENSG00000124214homo_sapiensENSP0000036092299.480199.4801macaca_fascicularisENSMFAP0000000140299.480199.4801
ENSG00000124214homo_sapiensENSP0000036092299.480199.4801macaca_mulattaENSMMUP0000000307999.480199.4801
ENSG00000124214homo_sapiensENSP0000036092299.480199.4801macaca_nemestrinaENSMNEP0000002015699.480199.4801
ENSG00000124214homo_sapiensENSP0000036092299.480199.4801papio_anubisENSPANP0000001466999.480199.4801
ENSG00000124214homo_sapiensENSP0000036092296.360594.8007mandrillus_leucophaeusENSMLEP0000001446595.042793.5043
ENSG00000124214homo_sapiensENSP0000036092288.561585.9619tursiops_truncatusENSTTRP0000000403188.869686.2609
ENSG00000124214homo_sapiensENSP0000036092297.920396.8804vulpes_vulpesENSVVUP0000003059583.333382.4484
ENSG00000124214homo_sapiensENSP0000036092280.935977.123mus_spretusMGP_SPRETEiJ_P005845194.343489.899
ENSG00000124214homo_sapiensENSP0000036092298.613597.5737equus_asinusENSEASP0000504639684.798883.9046
ENSG00000124214homo_sapiensENSP0000036092233.448931.7158capra_hircusENSCHIP0000002046886.160781.6964
ENSG00000124214homo_sapiensENSP0000036092297.400395.1473capra_hircusENSCHIP0000000110197.400395.1473
ENSG00000124214homo_sapiensENSP0000036092285.788684.2288loxodonta_africanaENSLAFP0000000269397.249595.4813
ENSG00000124214homo_sapiensENSP0000036092298.266996.5338panthera_leoENSPLOP0000000301783.628382.1534
ENSG00000124214homo_sapiensENSP0000036092297.74796.1872ailuropoda_melanoleucaENSAMEP0000001444197.74796.1872
ENSG00000124214homo_sapiensENSP0000036092297.22795.4939bos_indicus_hybridENSBIXP0000501543482.865681.3885
ENSG00000124214homo_sapiensENSP0000036092297.400394.4541oryctolagus_cuniculusENSOCUP0000000538297.400394.4541
ENSG00000124214homo_sapiensENSP0000036092298.440297.4003equus_caballusENSECAP0000003482882.678381.8049
ENSG00000124214homo_sapiensENSP0000036092286.135285.0953canis_lupus_familiarisENSCAFP0084503364382.013281.0231
ENSG00000124214homo_sapiensENSP0000036092298.440296.7071panthera_pardusENSPPRP0000000860698.440296.7071
ENSG00000124214homo_sapiensENSP0000036092283.362281.8024marmota_marmota_marmotaENSMMMP0000000813997.171795.3535
ENSG00000124214homo_sapiensENSP0000036092298.786897.0537balaenoptera_musculusENSBMSP0001002677098.786897.0537
ENSG00000124214homo_sapiensENSP0000036092280.589379.0295cavia_porcellusENSCPOP0000000501397.077295.1983
ENSG00000124214homo_sapiensENSP0000036092298.440296.8804felis_catusENSFCAP0000001951183.775882.4484
ENSG00000124214homo_sapiensENSP0000036092283.882182.4957ursus_americanusENSUAMP0000003341896.222794.6322
ENSG00000124214homo_sapiensENSP0000036092296.533892.8943monodelphis_domesticaENSMODP0000002035083.258680.1196
ENSG00000124214homo_sapiensENSP0000036092297.053795.3206bison_bison_bisonENSBBBP0000000193397.053795.3206
ENSG00000124214homo_sapiensENSP0000036092298.960197.227monodon_monocerosENSMMNP0001500226798.960197.227
ENSG00000124214homo_sapiensENSP0000036092298.786897.4003sus_scrofaENSSSCP0000003393982.969481.8049
ENSG00000124214homo_sapiensENSP0000036092298.266997.0537microcebus_murinusENSMICP0000003114497.255696.0549
ENSG00000124214homo_sapiensENSP0000036092284.228882.4957octodon_degusENSODEP0000000872698.380696.3563
ENSG00000124214homo_sapiensENSP0000036092282.322479.7227jaculus_jaculusENSJJAP0000001892697.13794.0695
ENSG00000124214homo_sapiensENSP0000036092297.400395.1473ovis_aries_rambouilletENSOARP0002003065797.400395.1473
ENSG00000124214homo_sapiensENSP0000036092266.724463.6049ursus_maritimusENSUMAP0000003395890.375686.1502
ENSG00000124214homo_sapiensENSP0000036092292.20188.0416ochotona_princepsENSOPRP0000001329793.169988.9667
ENSG00000124214homo_sapiensENSP0000036092280.415975.9099delphinapterus_leucasENSDLEP0000000304866.858863.1124
ENSG00000124214homo_sapiensENSP0000036092284.748783.0156physeter_catodonENSPCTP0000500835797.410495.4183
ENSG00000124214homo_sapiensENSP0000036092281.109277.9896mus_caroliMGP_CAROLIEiJ_P005628094.545590.9091
ENSG00000124214homo_sapiensENSP0000036092281.109277.4697mus_musculusENSMUSP0000010486194.545590.303
ENSG00000124214homo_sapiensENSP0000036092280.762677.2964dipodomys_ordiiENSDORP0000002613894.141490.101
ENSG00000124214homo_sapiensENSP0000036092297.400395.8406mustela_putorius_furoENSMPUP0000001746883.755682.4143
ENSG00000124214homo_sapiensENSP0000036092299.653499.4801aotus_nancymaaeENSANAP0000003006498.627898.4563
ENSG00000124214homo_sapiensENSP0000036092299.480199.3068saimiri_boliviensis_boliviensisENSSBOP0000003668598.456398.2847
ENSG00000124214homo_sapiensENSP0000036092298.440297.4003vicugna_pacosENSVPAP0000000121298.611197.5694
ENSG00000124214homo_sapiensENSP0000036092285.268685.2686chlorocebus_sabaeusENSCSAP0000001108899.193699.1936
ENSG00000124214homo_sapiensENSP0000036092285.441984.2288tupaia_belangeriENSTBEP0000000814385.590384.375
ENSG00000124214homo_sapiensENSP0000036092280.762677.2964mesocricetus_auratusENSMAUP0000001395994.141490.101
ENSG00000124214homo_sapiensENSP0000036092298.960197.227phocoena_sinusENSPSNP0000003022998.960197.227
ENSG00000124214homo_sapiensENSP0000036092298.960197.747camelus_dromedariusENSCDRP0000501931998.960197.747
ENSG00000124214homo_sapiensENSP0000036092297.400395.4939carlito_syrichtaENSTSYP0000003123397.400395.4939
ENSG00000124214homo_sapiensENSP0000036092263.604960.4853carlito_syrichtaENSTSYP0000000928889.95185.5392
ENSG00000124214homo_sapiensENSP0000036092298.440296.7071panthera_tigris_altaicaENSPTIP0000001149998.440296.7071
ENSG00000124214homo_sapiensENSP0000036092280.935977.8163rattus_norvegicusENSRNOP0000001063394.343490.7071
ENSG00000124214homo_sapiensENSP0000036092296.880495.6672prolemur_simusENSPSMP0000001725191.940890.7895
ENSG00000124214homo_sapiensENSP0000036092280.935977.9896microtus_ochrogasterENSMOCP0000002136390.503987.2093
ENSG00000124214homo_sapiensENSP0000036092261.698459.2721sorex_araneusENSSARP0000000938961.698459.2721
ENSG00000124214homo_sapiensENSP0000036092281.455877.8163peromyscus_maniculatus_bairdiiENSPEMP0000002569994.949590.7071
ENSG00000124214homo_sapiensENSP0000036092297.22795.4939bos_mutusENSBMUP0000000705383.606682.1162
ENSG00000124214homo_sapiensENSP0000036092281.109277.2964mus_spicilegusENSMSIP0000003761294.545590.101
ENSG00000124214homo_sapiensENSP0000036092280.935977.643cricetulus_griseus_chok1gshdENSCGRP0000101193694.343490.5051
ENSG00000124214homo_sapiensENSP0000036092284.748783.3622pteropus_vampyrusENSPVAP0000001415784.895883.5069
ENSG00000124214homo_sapiensENSP0000036092298.440296.7071myotis_lucifugusENSMLUP0000000768396.108394.4162
ENSG00000124214homo_sapiensENSP0000036092288.561585.2686vombatus_ursinusENSVURP0001000061482.419479.3548
ENSG00000124214homo_sapiensENSP0000036092298.440297.0537rhinolophus_ferrumequinumENSRFEP0001002336297.427196.0549
ENSG00000124214homo_sapiensENSP0000036092297.400395.8406neovison_visonENSNVIP0000001041397.400395.8406
ENSG00000124214homo_sapiensENSP0000036092297.22795.4939bos_taurusENSBTAP0000000030197.22795.4939
ENSG00000124214homo_sapiensENSP0000036092298.613596.8804heterocephalus_glaber_femaleENSHGLP0000001221098.613596.8804
ENSG00000124214homo_sapiensENSP0000036092254.246150.6066heterocephalus_glaber_femaleENSHGLP0000003025490.201784.1499
ENSG00000124214homo_sapiensENSP0000036092285.441985.4419rhinopithecus_bietiENSRBIP0000002696298.207298.2072
ENSG00000124214homo_sapiensENSP0000036092297.74796.7071canis_lupus_dingoENSCAFP0002002166183.185882.3009
ENSG00000124214homo_sapiensENSP0000036092297.74796.3605sciurus_vulgarisENSSVLP0000500528797.74796.3605
ENSG00000124214homo_sapiensENSP0000036092296.533893.0676phascolarctos_cinereusENSPCIP0000003140683.258680.2691
ENSG00000124214homo_sapiensENSP0000036092284.92283.7088procavia_capensisENSPCAP0000000232190.073588.7868
ENSG00000124214homo_sapiensENSP0000036092281.975780.2426nannospalax_galiliENSNGAP0000000511995.555693.5354
ENSG00000124214homo_sapiensENSP0000036092297.22795.4939bos_grunniensENSBGRP0000004033697.22795.4939
ENSG00000124214homo_sapiensENSP0000036092283.708882.3224chinchilla_lanigeraENSCLAP0000000938497.575895.9596
ENSG00000124214homo_sapiensENSP0000036092271.230567.2444chinchilla_lanigeraENSCLAP0000000391490.329785.2747
ENSG00000124214homo_sapiensENSP0000036092284.055581.6291cervus_hanglu_yarkandensisENSCHYP0000003866896.613593.8247
ENSG00000124214homo_sapiensENSP0000036092289.254887.8683catagonus_wagneriENSCWAP0000000771197.72396.2049
ENSG00000124214homo_sapiensENSP0000036092283.188981.6291ictidomys_tridecemlineatusENSSTOP0000000325398.159596.319
ENSG00000124214homo_sapiensENSP0000036092263.604957.539otolemur_garnettiiENSOGAP0000002152578.755471.2446
ENSG00000124214homo_sapiensENSP0000036092297.920396.8804otolemur_garnettiiENSOGAP0000000190495.600794.5854
ENSG00000124214homo_sapiensENSP0000036092299.480199.3068cebus_imitatorENSCCAP0000003266698.456398.2847
ENSG00000124214homo_sapiensENSP0000036092289.428187.8683urocitellus_parryiiENSUPAP0001002785798.473396.7557
ENSG00000124214homo_sapiensENSP0000036092284.055581.9757moschus_moschiferusENSMMSP0000000129696.613594.2231
ENSG00000124214homo_sapiensENSP0000036092299.480199.4801rhinopithecus_roxellanaENSRROP0000003054999.480199.4801
ENSG00000124214homo_sapiensENSP0000036092280.762677.643mus_pahariMGP_PahariEiJ_P006726294.141490.5051
ENSG00000124214homo_sapiensENSP0000036092298.613597.4003propithecus_coquereliENSPCOP0000003007998.613597.4003
ENSG00000124214homo_sapiensENSP0000036092221.663810.2253caenorhabditis_elegansY95B8A.8.116.36137.72251
ENSG00000124214homo_sapiensENSP0000036092216.81119.35875drosophila_melanogasterFBpp008007620.860211.6129
ENSG00000124214homo_sapiensENSP0000036092211.43857.45234drosophila_melanogasterFBpp007685620.370413.2716
ENSG00000124214homo_sapiensENSP0000036092211.09196.58579drosophila_melanogasterFBpp007321921.621612.8378
ENSG00000124214homo_sapiensENSP0000036092221.14389.01213drosophila_melanogasterFBpp030548913.80095.88235
ENSG00000124214homo_sapiensENSP0000036092212.8257.10572ciona_intestinalisENSCINP0000001280524.666713.6667
ENSG00000124214homo_sapiensENSP0000036092212.13174.67938ciona_intestinalisENSCINP0000003451818.76687.23861
ENSG00000124214homo_sapiensENSP0000036092221.31729.70537ciona_intestinalisENSCINP0000001004612.98845.91341
ENSG00000124214homo_sapiensENSP0000036092217.15777.62565ciona_intestinalisENSCINP0000002604211.87055.27578
ENSG00000124214homo_sapiensENSP0000036092282.14972.0971callorhinchus_miliiENSCMIP0000002918468.201459.8561
ENSG00000124214homo_sapiensENSP0000036092290.641383.1889latimeria_chalumnaeENSLACP0000001834572.337566.39
ENSG00000124214homo_sapiensENSP0000036092285.788675.9099lepisosteus_oculatusENSLOCP0000000370171.325663.1124
ENSG00000124214homo_sapiensENSP0000036092280.415968.9775clupea_harengusENSCHAP0000005570966.666757.1839
ENSG00000124214homo_sapiensENSP0000036092280.415970.7106danio_rerioENSDARP0000014886666.096958.1197
ENSG00000124214homo_sapiensENSP0000036092277.816368.4575carassius_auratusENSCARP0000000578365.166957.3295
ENSG00000124214homo_sapiensENSP0000036092280.415969.6707carassius_auratusENSCARP0000008700161.052652.8947
ENSG00000124214homo_sapiensENSP0000036092280.762670.7106astyanax_mexicanusENSAMXP0000001730782.332272.0848
ENSG00000124214homo_sapiensENSP0000036092278.162968.1109ictalurus_punctatusENSIPUP0000003539268.54159.7264
ENSG00000124214homo_sapiensENSP0000036092281.455868.9775esox_luciusENSELUP0000000097465.459655.4318
ENSG00000124214homo_sapiensENSP0000036092279.029568.9775electrophorus_electricusENSEEEP0000004468666.862258.3578
ENSG00000124214homo_sapiensENSP0000036092280.242667.7643oncorhynchus_kisutchENSOKIP0000500521665.76755.5398
ENSG00000124214homo_sapiensENSP0000036092279.376167.9376oncorhynchus_kisutchENSOKIP0000506808062.059653.1165
ENSG00000124214homo_sapiensENSP0000036092279.202867.7643oncorhynchus_mykissENSOMYP0000013563764.639355.3041
ENSG00000124214homo_sapiensENSP0000036092280.589368.1109oncorhynchus_mykissENSOMYP0000013730865.957455.7447
ENSG00000124214homo_sapiensENSP0000036092277.469765.1646salmo_salarENSSSAP0000007502563.314453.2578
ENSG00000124214homo_sapiensENSP0000036092279.202867.7643salmo_salarENSSSAP0000011205064.639355.3041
ENSG00000124214homo_sapiensENSP0000036092280.069367.7643salmo_truttaENSSTUP0000008987965.718455.6188
ENSG00000124214homo_sapiensENSP0000036092279.202867.591salmo_truttaENSSTUP0000003122064.639355.1627
ENSG00000124214homo_sapiensENSP0000036092275.563362.9116gadus_morhuaENSGMOP0000006198159.80849.7942
ENSG00000124214homo_sapiensENSP0000036092281.109269.1508fundulus_heteroclitusENSFHEP0000001203467.338157.4101
ENSG00000124214homo_sapiensENSP0000036092280.242669.3241poecilia_reticulataENSPREP0000000495166.52357.4713
ENSG00000124214homo_sapiensENSP0000036092280.589369.844xiphophorus_maculatusENSXMAP0000001621766.906557.9856
ENSG00000124214homo_sapiensENSP0000036092281.802469.3241cyclopterus_lumpusENSCLMP0000503926667.621857.3066
ENSG00000124214homo_sapiensENSP0000036092281.455869.4974oreochromis_niloticusENSONIP0000000523066.856357.0413
ENSG00000124214homo_sapiensENSP0000036092281.802469.3241haplochromis_burtoniENSHBUP0000003545968.208157.8035
ENSG00000124214homo_sapiensENSP0000036092281.802469.1508astatotilapia_callipteraENSACLP0000001803468.208157.659
ENSG00000124214homo_sapiensENSP0000036092281.629170.364sparus_aurataENSSAUP0001000702667.189757.9173
ENSG00000124214homo_sapiensENSP0000036092282.322470.364lates_calcariferENSLCAP0001002058968.345358.4173
ENSG00000124214homo_sapiensENSP0000036092290.814681.1092xenopus_tropicalisENSXETP0000006849273.492365.6381
ENSG00000124214homo_sapiensENSP0000036092294.800789.0815chrysemys_picta_belliiENSCPBP0000003870678.59273.8506
ENSG00000124214homo_sapiensENSP0000036092294.627488.5615sphenodon_punctatusENSSPUP0000002343678.223573.2092
ENSG00000124214homo_sapiensENSP0000036092294.800788.7348crocodylus_porosusENSCPRP0000501213777.369272.4187
ENSG00000124214homo_sapiensENSP0000036092294.280887.8683laticauda_laticaudataENSLLTP0000000982478.048872.7403
ENSG00000124214homo_sapiensENSP0000036092294.454188.0416notechis_scutatusENSNSUP0000001968978.192372.8838
ENSG00000124214homo_sapiensENSP0000036092294.454188.2149pseudonaja_textilisENSPTXP0000000304078.192373.0273
ENSG00000124214homo_sapiensENSP0000036092294.454188.5615anas_platyrhynchos_platyrhynchosENSAPLP0000001035076.544971.7697
ENSG00000124214homo_sapiensENSP0000036092294.454188.9081gallus_gallusENSGALP0001003558378.985574.3478
ENSG00000124214homo_sapiensENSP0000036092294.280888.7348meleagris_gallopavoENSMGAP0000000457976.404571.9101
ENSG00000124214homo_sapiensENSP0000036092294.454188.2149serinus_canariaENSSCAP0000002171278.985573.7681
ENSG00000124214homo_sapiensENSP0000036092294.627488.5615parus_majorENSPMJP0000001193679.130474.058
ENSG00000124214homo_sapiensENSP0000036092293.760887.8683anolis_carolinensisENSACAP0000001566477.396372.5322
ENSG00000124214homo_sapiensENSP0000036092281.975769.3241neolamprologus_brichardiENSNBRP0000002299368.352657.8035
ENSG00000124214homo_sapiensENSP0000036092294.280887.8683naja_najaENSNNAP0000000139378.048872.7403
ENSG00000124214homo_sapiensENSP0000036092294.627488.7348podarcis_muralisENSPMRP0000001561178.111673.2475
ENSG00000124214homo_sapiensENSP0000036092294.454188.2149geospiza_fortisENSGFOP0000000258878.985573.7681
ENSG00000124214homo_sapiensENSP0000036092294.454188.0416taeniopygia_guttataENSTGUP0000001902778.985573.6232
ENSG00000124214homo_sapiensENSP0000036092284.575473.8302erpetoichthys_calabaricusENSECRP0000001292669.714360.8571
ENSG00000124214homo_sapiensENSP0000036092280.242668.1109kryptolebias_marmoratusENSKMAP0000000954067.296557.1221
ENSG00000124214homo_sapiensENSP0000036092294.627488.7348salvator_merianaeENSSMRP0000000666073.883669.2828
ENSG00000124214homo_sapiensENSP0000036092279.89668.4575oryzias_javanicusENSOJAP0000000633866.235656.7529
ENSG00000124214homo_sapiensENSP0000036092282.14970.1906amphilophus_citrinellusENSACIP0000002051569.603559.4714
ENSG00000124214homo_sapiensENSP0000036092282.322470.8839amphiprion_perculaENSAPEP0000001724468.74159.1896
ENSG00000124214homo_sapiensENSP0000036092279.376167.7643oryzias_sinensisENSOSIP0000001294966.089556.4214
ENSG00000124214homo_sapiensENSP0000036092234.835430.156oryzias_sinensisENSOSIP000000041337564.9254
ENSG00000124214homo_sapiensENSP0000036092294.280888.2149pelodiscus_sinensisENSPSIP0000001188578.386273.3429
ENSG00000124214homo_sapiensENSP0000036092294.454188.7348gopherus_evgoodeiENSGEVP0000500770678.985574.2029
ENSG00000124214homo_sapiensENSP0000036092294.280888.5615chelonoidis_abingdoniiENSCABP0000002677878.840674.058
ENSG00000124214homo_sapiensENSP0000036092282.322471.4038seriola_dumeriliENSSDUP0000002681268.74159.6237
ENSG00000124214homo_sapiensENSP0000036092279.376167.2444cottoperca_gobioENSCGOP0000001330665.710255.6671
ENSG00000124214homo_sapiensENSP0000036092294.627488.2149struthio_camelus_australisENSSCUP0000000774778.448373.1322
ENSG00000124214homo_sapiensENSP0000036092294.454188.7348anser_brachyrhynchusENSABRP0000002512176.544971.9101
ENSG00000124214homo_sapiensENSP0000036092281.629169.6707gasterosteus_aculeatusENSGACP0000000176165.874156.2238
ENSG00000124214homo_sapiensENSP0000036092275.909964.2981cynoglossus_semilaevisENSCSEP0000000114365.765855.7057
ENSG00000124214homo_sapiensENSP0000036092280.762670.0173poecilia_formosaENSPFOP0000001735766.95458.046
ENSG00000124214homo_sapiensENSP0000036092281.802470.364myripristis_murdjanENSMMDP0000502652567.718858.2496
ENSG00000124214homo_sapiensENSP0000036092281.975770.364sander_luciopercaENSSLUP0000002753368.155658.5014
ENSG00000124214homo_sapiensENSP0000036092294.627488.7348strigops_habroptilaENSSHBP0000500817778.448373.5632
ENSG00000124214homo_sapiensENSP0000036092282.322470.8839amphiprion_ocellarisENSAOCP0000000824468.74159.1896
ENSG00000124214homo_sapiensENSP0000036092294.97488.9081terrapene_carolina_triunguisENSTMTP0000000303180.234375.1098
ENSG00000124214homo_sapiensENSP0000036092275.043364.1248hucho_huchoENSHHUP0000002925063.211754.0146
ENSG00000124214homo_sapiensENSP0000036092280.589368.4575hucho_huchoENSHHUP0000001859366.051156.108
ENSG00000124214homo_sapiensENSP0000036092281.455869.6707betta_splendensENSBSLP0000001829367.625957.8417
ENSG00000124214homo_sapiensENSP0000036092281.109270.8839pygocentrus_nattereriENSPNAP0000000483867.826159.2754
ENSG00000124214homo_sapiensENSP0000036092282.14970.364anabas_testudineusENSATEP0000003580468.201458.4173
ENSG00000124214homo_sapiensENSP000003609227.452342.77296ciona_savignyiENSCSAVP0000000326617.40896.47773
ENSG00000124214homo_sapiensENSP000003609224.506072.59965ciona_savignyiENSCSAVP0000001152912.3817.14286
ENSG00000124214homo_sapiensENSP0000036092282.322471.2305seriola_lalandi_dorsalisENSSLDP0000003264568.74159.479
ENSG00000124214homo_sapiensENSP0000036092280.242667.9376labrus_bergyltaENSLBEP0000002653267.004356.7294
ENSG00000124214homo_sapiensENSP0000036092281.802469.3241pundamilia_nyerereiENSPNYP0000001911368.208157.8035
ENSG00000124214homo_sapiensENSP0000036092282.322471.2305mastacembelus_armatusENSMAMP0000002618168.345359.1367
ENSG00000124214homo_sapiensENSP0000036092282.495770.8839stegastes_partitusENSSPAP0000002550268.885759.1896
ENSG00000124214homo_sapiensENSP0000036092277.64365.338oncorhynchus_tshawytschaENSOTSP0000505595663.456153.3994
ENSG00000124214homo_sapiensENSP0000036092279.376167.7643oncorhynchus_tshawytschaENSOTSP0000503964664.780855.3041
ENSG00000124214homo_sapiensENSP0000036092281.975769.6707acanthochromis_polyacanthusENSAPOP0000003055568.451558.1766
ENSG00000124214homo_sapiensENSP0000036092294.627488.9081aquila_chrysaetos_chrysaetosENSACCP0002001410277.337172.6629
ENSG00000124214homo_sapiensENSP0000036092279.89669.3241nothobranchius_furzeriENSNFUP0001500974167.103358.2242
ENSG00000124214homo_sapiensENSP0000036092278.336268.2842cyprinodon_variegatusENSCVAP0000002290780.714370.3571
ENSG00000124214homo_sapiensENSP0000036092280.935970.7106denticeps_clupeoidesENSDCDP0000004801967.388258.8745
ENSG00000124214homo_sapiensENSP0000036092278.682866.7244larimichthys_croceaENSLCRP0000503092665.04355.1576
ENSG00000124214homo_sapiensENSP0000036092281.109269.844takifugu_rubripesENSTRUP0000001422867.435258.0692
ENSG00000124214homo_sapiensENSP0000036092294.107587.0017ficedula_albicollisENSFALP0000001350678.695772.7536
ENSG00000124214homo_sapiensENSP0000036092279.029566.5511hippocampus_comesENSHCOP0000001493565.800955.4113
ENSG00000124214homo_sapiensENSP0000036092280.589370.5373cyprinus_carpio_carpioENSCCRP0000009647662.668554.8518
ENSG00000124214homo_sapiensENSP0000036092294.454188.3882coturnix_japonicaENSCJPP0000500225077.195572.238
ENSG00000124214homo_sapiensENSP0000036092247.48739.5147poecilia_latipinnaENSPLAP0000002675260.219850.1099
ENSG00000124214homo_sapiensENSP0000036092280.415970.5373sinocyclocheilus_grahamiENSSGRP0000007651066.191258.0599
ENSG00000124214homo_sapiensENSP0000036092281.802469.1508maylandia_zebraENSMZEP0000502081168.306857.7424
ENSG00000124214homo_sapiensENSP0000036092278.856267.9376tetraodon_nigroviridisENSTNIP0000001776867.307757.9882
ENSG00000124214homo_sapiensENSP0000036092283.362270.5373paramormyrops_kingsleyaeENSPKIP0000000951169.208658.5611
ENSG00000124214homo_sapiensENSP0000036092283.188972.0971scleropages_formosusENSSFOP0001504387967.892558.8402
ENSG00000124214homo_sapiensENSP0000036092288.734877.9896leptobrachium_leishanenseENSLLEP0000001992672.316463.5593
ENSG00000124214homo_sapiensENSP0000036092281.455870.364scophthalmus_maximusENSSMAP0000006339467.047157.9173
ENSG00000124214homo_sapiensENSP0000036092279.549468.2842oryzias_melastigmaENSOMEP0000000149166.521757.1014

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003725enables double-stranded RNA binding1IBAHomo_sapiens(9606)Function
GO:0003729enables mRNA binding1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005783located_in endoplasmic reticulum1IDAHomo_sapiens(9606)Component
GO:0005791located_in rough endoplasmic reticulum1IEAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0005875part_of microtubule associated complex1TASHomo_sapiens(9606)Component
GO:0005886is_active_in plasma membrane2IBA,IDAHomo_sapiens(9606)Component
GO:0007281involved_in germ cell development1IBAHomo_sapiens(9606)Process
GO:0008157enables protein phosphatase 1 binding1IEAHomo_sapiens(9606)Function
GO:0008298involved_in intracellular mRNA localization1IBAHomo_sapiens(9606)Process
GO:0010494is_active_in cytoplasmic stress granule2IBA,ISSHomo_sapiens(9606)Component
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0030425located_in dendrite1IDAHomo_sapiens(9606)Component
GO:0032839located_in dendrite cytoplasm1IEAHomo_sapiens(9606)Component
GO:0034599involved_in cellular response to oxidative stress1IEAHomo_sapiens(9606)Process
GO:0035418involved_in protein localization to synapse1IBAHomo_sapiens(9606)Process
GO:0036464located_in cytoplasmic ribonucleoprotein granule1IDAHomo_sapiens(9606)Component
GO:0043005is_active_in neuron projection1IBAHomo_sapiens(9606)Component
GO:0043025is_active_in neuronal cell body1IBAHomo_sapiens(9606)Component
GO:0044297located_in cell body1IDAHomo_sapiens(9606)Component
GO:0045070involved_in positive regulation of viral genome replication1IMPHomo_sapiens(9606)Process
GO:0046726involved_in positive regulation by virus of viral protein levels in host cell1IMPHomo_sapiens(9606)Process
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component
GO:0098964involved_in anterograde dendritic transport of messenger ribonucleoprotein complex1IBAHomo_sapiens(9606)Process
GO:0098978located_in glutamatergic synapse1IEAHomo_sapiens(9606)Component
GO:0099010involved_in modification of postsynaptic structure1IEAHomo_sapiens(9606)Process
GO:1900273involved_in positive regulation of long-term synaptic potentiation1IEAHomo_sapiens(9606)Process
GO:1990124part_of messenger ribonucleoprotein complex1IBAHomo_sapiens(9606)Component

Expression