Ensembl ID ENSG00000124214 Gene ID 6780 Accession 11370
Gene Symbol STAU1 Alias STAU;PPP1R150 Full Name staufen double-stranded RNA binding protein 1
Position 20 : 49113339 - 49188367 Length 75029 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. [provided by RefSeq, Apr 2020]

ENSG00000124214 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000124214 STAU1 0.50 3.22e-26 BRCA
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000124214 STAU1 colorectal cancer 28004750
ENSG00000124214 STAU1 gastric cancer 28569791
ENSG00000124214 STAU1 Cancer 29108255
ENSG00000124214 STAU1 tumor 30718359
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000124214 STAU1 SARC 0.015 high
ENSG00000124214 STAU1 CHOL 0.05 low
ENSG00000124214 STAU1 UVM 0.05 low
ENSG00000124214 STAU1 PAAD 0.0073 high
ENSG00000124214 STAU1 UCEC 0.0023 high
ENSG00000124214 STAU1 PCPG 0.0044 high
ENSG00000124214 STAU1 BRCA 0.01 high
ENSG00000124214 STAU1 PRAD 0.00065 high
ENSG00000124214 STAU1 BLCA 0.027 high
ENSG00000124214 STAU1 LAML 0.012 high
ENSG00000124214 STAU1 LIHC 0.011 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000124214 STAU1 READ Amp 2.155434 0.196430 1.330067 0.890909
ENSG00000124214 STAU1 COAD Amp 4.721134 0.136591 1.190691 0.725055
ENSG00000124214 STAU1 BRCA Amp 5.579171 0.218699 0.643587 0.467593
ENSG00000124214 STAU1 STAD Amp 2.983253 0.193804 0.707235 0.664399
ENSG00000124214 STAU1 PRAD Amp 0.656974 0.044530 0.405558 0.075203