Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerFlavivirusesSARS-COV-2Dengue
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq DataSet_01_109 DataSet_01_77 DataSet_02_144 DataSet_02_145

Description

Ensembl ID ENSG00000112531 Gene ID 9444 Accession 21100
Symbol QKI Alias QK;Hqk;QK1;QK3;hqkI Full Name QKI, KH domain containing RNA binding
Status Confidence Length 164593 bases Strand Plus strand
Position 6 : 163414000 - 163578592 RNA binding domain KH_1 , STAR_dimer
Summary The protein encoded by this gene is an RNA-binding protein that regulates pre-mRNA splicing, export of mRNAs from the nucleus, protein translation, and mRNA stability. The encoded protein is involved in myelinization and oligodendrocyte differentiation and may play a role in schizophrenia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000443690 KH_1 PF00013 3.9e-06 1
ENSP00000440991 KH_1 PF00013 6.5e-06 1
ENSP00000440599 KH_1 PF00013 7.6e-06 1
ENSP00000408382 KH_1 PF00013 2.2e-05 1
ENSP00000408382 STAR_dimer PF16544 1.6e-26 2
ENSP00000354951 KH_1 PF00013 2.3e-05 1
ENSP00000354951 STAR_dimer PF16544 1.6e-26 2
ENSP00000408775 KH_1 PF00013 2.3e-05 1
ENSP00000408775 STAR_dimer PF16544 1.6e-26 2
ENSP00000375973 KH_1 PF00013 2.3e-05 1
ENSP00000375973 STAR_dimer PF16544 1.6e-26 2
ENSP00000354867 KH_1 PF00013 2.4e-05 1
ENSP00000354867 STAR_dimer PF16544 1.7e-26 2
ENSP00000275262 KH_1 PF00013 2.4e-05 1
ENSP00000275262 STAR_dimer PF16544 1.7e-26 2
ENSP00000355094 KH_1 PF00013 2.5e-05 1
ENSP00000355094 STAR_dimer PF16544 1.8e-26 2
ENSP00000437867 STAR_dimer PF16544 1.3e-15 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
29861871 The miR-17-92 cluster/QKI2/β-catenin axis promotes osteosarcoma progression. Hongbo Yang 2018-05-18 Oncotarget
19435871 MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents. R Dawn Cochrane 2009-05-01 Molecular cancer therapeutics
33114089 Comparison of MicroRNA Transcriptomes Reveals the Association between MiR-148a-3p Expression and Rumen Development in Goats. Tao Zhong 2020-10-23 Animals : an open access journal from MDPI
33368549 MOBP and HIP1 in multiple system atrophy: New α-synuclein partners in glial cytoplasmic inclusions implicated in the disease pathogenesis. Conceição Bettencourt 2021-08-01 Neuropathology and applied neurobiology
31331967 The RNA-binding protein QKI controls alternative splicing in vascular cells, producing an effective model for therapy. Rachel Caines 2019-08-15 Journal of cell science
17575274 The selective RNA-binding protein quaking I (QKI) is necessary and sufficient for promoting oligodendroglia differentiation. Yuntao Chen 2007-08-10 The Journal of biological chemistry
32931453 Long non-coding RNA Loc490 inhibits gastric cancer cell proliferation and metastasis by upregulating RNA-binding protein Quaking. Zhengxi He 2020-09-15 Aging
24799664 CAHM, a long non-coding RNA gene hypermethylated in colorectal neoplasia. K Susanne Pedersen 2014-08-01 Epigenetics
23319046 The QKI-5 and QKI-6 RNA binding proteins regulate the expression of microRNA 7 in glial cells. Yunling Wang 2013-03-01 Molecular and cellular biology
36104321 The emerging roles of circular RNA-mediated autophagy in tumorigenesis and cancer progression. Yuan Yuan 2022-09-14 Cell death discovery
35298877 The Quaking RNA-binding proteins as regulators of cell differentiation. P Daniel Neumann 2022-11-01 Wiley interdisciplinary reviews. RNA
23321059 RNA-binding protein QKI regulates Glial fibrillary acidic protein expression in human astrocytes. J Katarzyna Radomska 2013-04-01 Human molecular genetics
26349458 An intriguing RNA species--perspectives of circularized RNA. Ting Shen 2015-12-01 Protein & cell
21768773 E2F1 and RNA binding protein QKI comprise a negative feedback in the cell cycle regulation. Guodong Yang 2011-08-15 Cell cycle (Georgetown, Tex.)
22398723 The RNA-binding protein QKI5 is a direct target of C/EBPα and delays macrophage differentiation. Haiyan Fu 2012-05-01 Molecular biology of the cell
31289476 Overexpression of miR-20a promotes the progression of osteosarcoma by directly targeting QKI2. Hongbo Yang 2019-07-01 Oncology letters
32536039 Proteomic analysis enables distinction of early- versus advanced-stage lung adenocarcinomas. Olga Kelemen 2020-06-01 Clinical and translational medicine
33196842 QKI-5 regulates the alternative splicing of cytoskeletal gene ADD3 in lung cancer. Jin-Zhu Wang 2021-08-18 Journal of molecular cell biology
21972111 Nonsense mutation-associated Becker muscular dystrophy: interplay between exon definition and splicing regulatory elements within the DMD gene. M Kevin Flanigan 2011-03-01 Human mutation
34784346 Alternative poly-adenylation modulates α1-antitrypsin expression in chronic obstructive pulmonary disease. Lela Lackey 2021-11-01 PLoS genetics
29572260 Identification and characterization of host proteins bound to dengue virus 3' UTR reveal an antiviral role for quaking proteins. Kuo-Chieh Liao 2018-06-01 RNA (New York, N.Y.)
25934039 Altered expression of neuroplasticity-related genes in the brain of depressed suicides. B Fuchsova 2015-07-23 Neuroscience
31127091 Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus. Jiawei Zhao 2019-05-24 Nature communications
36627445 RNA splicing dysregulation and the hallmarks of cancer. K Robert Bradley 2023-03-01 Nature reviews. Cancer

Transcripts

Name Transcript ID bp Protein Translation ID

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
992Body Height8.25066069845004E-517903300
1005Body Height1.17594809259103E-517903300
1016Body Height4.40768165814731E-517903300
1017Body Height5.81981414238621E-517903300
1021Body Height4.40768165814731E-517903300
1022Body Height4.4458022995908E-517903300
1063Body Height3.62763234362795E-517903300
1064Body Height4.68117494687448E-517903300
2036Body Weight3.69127265951175E-517903300
2215Body Weight Changes2.22427764085245E-617903300
4197Triglycerides1.58397429093284E-517903299
5836Carotid Artery Diseases8.1481609117029E-517903303
5926Aorta6.797508678276E-1817903303
5938Aorta3.01823459731801E-1717903303
5949Aorta2.31719215431588E-1517903303
5962Aorta1.18266148703311E-1517903303
7347Vitamin D3.61188581941008E-517903293
9550Echocardiography6.07187478532364E-517903301
9551Echocardiography4.6411424362347E-517903301
9677Echocardiography5.33915481124376E-617903301
9678Echocardiography5.73311798190979E-617903301
9682Echocardiography2.92524605299033E-617903301
9683Echocardiography6.22830791731421E-717903301
9684Echocardiography2.00799443155208E-517903301
9685Echocardiography4.47512638973126E-617903301
9697Echocardiography9.20722888706575E-617903301
9698Echocardiography9.64422832128164E-617903301
9701Echocardiography4.69442693592287E-617903301
9702Echocardiography1.1679425376545E-617903301
9703Echocardiography2.50887284445334E-517903301
9704Echocardiography7.39467436966642E-617903301
10216Pulse7.15715792973803E-517903302
10521Electrocardiography2.15687394881314E-517903302
10532Electrocardiography3.42791945327309E-517903302
13526lipoprotein A-I5.004556E-1619124843
13527lipoprotein A-I7.613696E-1119124843
13535lipoprotein A-I1.23446E-0719124843
13557lipoprotein A-I2.14934E-0719124843
13571lipoprotein A-I3.452318E-0819124843
13583lipoprotein A-I6.760902E-1419124843
13585lipoprotein A-I8.471534E-0819124843
13592lipoprotein A-I2.748571E-0919124843
13941Myocardial Infarction6.5810816E-005-
17597Alcoholism7.67293e-00522978509
17624Alcoholism9.1868e-00522978509
17645Alcoholism6.68083e-00522978509
17724Alcoholism3.16603e-00522978509
17747Alcoholism4.00055e-00522978509
17764Alcoholism4.73701e-00522978509
17814Alcoholism5.36976e-00522978509
21308Choice Behavior9.891e-005-
24129Body Fat Distribution5.6470000E-005-
24194Body Fat Distribution4.8960000E-005-
26166Arteries8.5500000E-005-
26170Arteries8.7940000E-005-
26195Arteries2.6970000E-005-
26196Arteries2.6970000E-005-
26207Arteries2.6970000E-005-
26212Arteries8.5500000E-005-
28369Nutritional and Metabolic Diseases7.1830000E-005-
30452Eosinophils4.8340000E-005-
30470Eosinophils4.1370000E-005-
31313Hematocrit5.9620000E-005-
31802Erythrocyte Count2.4220000E-006-
31910Respiratory Function Tests7.0060000E-005-
32484Blood Pressure7.3817246E-005-
32816Body Mass Index9.4799057E-005-
33700Body Mass Index5.3915346E-005-
33820Glomerular Filtration Rate8.9243970E-005-
35710Platelet Function Tests2.0368300E-005-
35737Platelet Function Tests2.2384000E-005-
36331Platelet Function Tests1.3185400E-005-
36460Platelet Function Tests1.0893800E-005-
36472Platelet Function Tests4.8300000E-006-
36511Platelet Function Tests1.4025300E-005-
36640Platelet Function Tests2.3700000E-006-
36658Platelet Function Tests1.6104900E-005-
44701Platelet Function Tests1.3050400E-005-
46572Liver Cirrhosis, Biliary1.0690000E-00520639880
48511Child Development Disorders, Pervasive9.2543000E-006-
48557Child Development Disorders, Pervasive1.6633000E-005-
52232Child Development Disorders, Pervasive9.8000000E-005-
52563Child Development Disorders, Pervasive9.9000000E-005-
53552Insulin4.7740000E-005-
54528alpha-Macroglobulins2.2980000E-005-
54799Fibrinogen2.6520000E-005-
55264Erythrocyte Indices2.5190000E-005-
55265Erythrocyte Indices2.5190000E-005-
55267Erythrocyte Indices2.5190000E-005-
57774Warfarin5.7160000E-005-
57787Warfarin5.8670000E-006-
57810Warfarin4.1740000E-006-
58841Coronary Disease9.9800000E-006-
58872Myocardial Infarction1.9630000E-007-
58878Myocardial Infarction3.1110000E-007-
58879Myocardial Infarction3.6530000E-006-
58880Myocardial Infarction1.4150000E-006-
73949Asthma7E-625918132
73950Toluene 2,4-Diisocyanate7E-625918132
75220Polychlorinated Biphenyls2E-725839716
77993Schizophrenia7E-626198764
79530Polychlorinated Biphenyls4E-825839716
82895Longevity5E-827015805
85572Myocardial Infarction6E-926950853
87027Adipose Tissue3E-622589738
87028Body Mass Index3E-622589738
87685Polychlorinated Biphenyls8E-725839716
92108Erythrocyte Count6E-728017375
92720Tumor Necrosis Factors3E-718615156
93019Psychotic Disorders1E-626821981
93020Schizophrenia1E-626821981
93021Antipsychotic Agents1E-626821981
94081Polychlorinated Biphenyls1E-725839716
95215Asthma2E-724824216
95264Gestational Age3E-627490719
95265Live Birth3E-627490719
102865Depressive Disorder9E-620516156
103048Alcoholism8E-727151647
104308Autosomal dominant compelling helio ophthalmic outburst syndrome3E-1027182965
104659Polychlorinated Biphenyls7E-725839716
106784Neurofibrillary Tangles4E-625188341

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000112531homo_sapiensENSP0000036660727.2317.2144homo_sapiensENSP0000035509451.026432.2581
ENSG00000112531homo_sapiensENSP0000028115641.260731.2321homo_sapiensENSP0000035509442.228731.9648
ENSG00000112531homo_sapiensENSP0000031382933.182825.5079homo_sapiensENSP0000035509443.108533.1378
ENSG00000112531homo_sapiensENSP0000034810841.618529.7688homo_sapiensENSP0000035509442.228730.2053

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000112531homo_sapiensENSP0000035509478.592478.5924nomascus_leucogenysENSNLEP0000001396391.467691.4676
ENSG00000112531homo_sapiensENSP0000035509491.202389.1496pan_paniscusENSPPAP0000003014458.568757.2505
ENSG00000112531homo_sapiensENSP00000355094100100pongo_abeliiENSPPYP00000019218100100
ENSG00000112531homo_sapiensENSP0000035509499.120298.827pan_troglodytesENSPTRP0000008546698.830498.538
ENSG00000112531homo_sapiensENSP0000035509499.120298.827gorilla_gorillaENSGGOP0000003718898.830498.538
ENSG00000112531homo_sapiensENSP0000035509499.120298.5337ornithorhynchus_anatinusENSOANP0000003579261.791661.426
ENSG00000112531homo_sapiensENSP0000035509497.360797.3607sarcophilus_harrisiiENSSHAP0000001660688.063788.0637
ENSG00000112531homo_sapiensENSP0000035509469.208269.2082notamacropus_eugeniiENSMEUP0000000739980.821980.8219
ENSG00000112531homo_sapiensENSP0000035509488.269887.0968choloepus_hoffmanniENSCHOP0000000588488.011786.8421
ENSG00000112531homo_sapiensENSP0000035509471.847571.5543erinaceus_europaeusENSEEUP0000001098283.617783.2765
ENSG00000112531homo_sapiensENSP0000035509485.630585.3372echinops_telfairiENSETEP0000000623299.658799.3174
ENSG00000112531homo_sapiensENSP00000355094100100callithrix_jacchusENSCJAP00000066622100100
ENSG00000112531homo_sapiensENSP0000035509479.765475.6598cercocebus_atysENSCATP0000001190286.624282.1656
ENSG00000112531homo_sapiensENSP0000035509499.120298.827cercocebus_atysENSCATP0000002868798.830498.538
ENSG00000112531homo_sapiensENSP00000355094100100macaca_fascicularisENSMFAP00000025087100100
ENSG00000112531homo_sapiensENSP0000035509497.65497.654macaca_mulattaENSMMUP00000000579100100
ENSG00000112531homo_sapiensENSP0000035509475.366672.1408macaca_nemestrinaENSMNEP0000000345884.818581.1881
ENSG00000112531homo_sapiensENSP0000035509493.841692.0821papio_anubisENSPANP0000004207361.776160.6178
ENSG00000112531homo_sapiensENSP0000035509480.645277.7126mandrillus_leucophaeusENSMLEP0000002341489.576586.3192
ENSG00000112531homo_sapiensENSP0000035509499.120298.827tursiops_truncatusENSTTRP0000001143097.97197.6812
ENSG00000112531homo_sapiensENSP00000355094100100vulpes_vulpesENSVVUP0000000179184.405984.4059
ENSG00000112531homo_sapiensENSP0000035509492.375491.7889mus_spretusMGP_SPRETEiJ_P004457696.923196.3077
ENSG00000112531homo_sapiensENSP00000355094100100equus_asinusENSEASP00005028979100100
ENSG00000112531homo_sapiensENSP00000355094100100capra_hircusENSCHIP00000020121100100
ENSG00000112531homo_sapiensENSP0000035509486.803586.217loxodonta_africanaENSLAFP0000002521996.73296.0784
ENSG00000112531homo_sapiensENSP0000035509483.87183.5777panthera_leoENSPLOP0000000595310099.6504
ENSG00000112531homo_sapiensENSP0000035509487.683386.5103ailuropoda_melanoleucaENSAMEP0000000889895.833394.5513
ENSG00000112531homo_sapiensENSP0000035509465.102658.651bos_indicus_hybridENSBIXP0000503306161.838455.7103
ENSG00000112531homo_sapiensENSP0000035509486.803585.9238oryctolagus_cuniculusENSOCUP0000000356485.797184.9275
ENSG00000112531homo_sapiensENSP0000035509490.029389.4428equus_caballusENSECAP0000003560296.845496.2145
ENSG00000112531homo_sapiensENSP0000035509492.375491.7889canis_lupus_familiarisENSCAFP0084500372696.923196.3077
ENSG00000112531homo_sapiensENSP0000035509410099.7067panthera_pardusENSPPRP0000002304710099.7067
ENSG00000112531homo_sapiensENSP0000035509488.856387.9765marmota_marmota_marmotaENSMMMP0000001033397.427796.463
ENSG00000112531homo_sapiensENSP0000035509499.706799.4135balaenoptera_musculusENSBMSP0001001423599.706799.4135
ENSG00000112531homo_sapiensENSP0000035509477.126172.434cavia_porcellusENSCPOP0000000309487.086181.7881
ENSG00000112531homo_sapiensENSP0000035509410099.7067felis_catusENSFCAP0000003779110099.7067
ENSG00000112531homo_sapiensENSP0000035509499.706799.7067monodelphis_domesticaENSMODP0000005473997.421297.4212
ENSG00000112531homo_sapiensENSP0000035509485.923885.9238bison_bison_bisonENSBBBP0000000753885.923885.9238
ENSG00000112531homo_sapiensENSP0000035509499.706799.4135monodon_monocerosENSMMNP0001501606699.706799.4135
ENSG00000112531homo_sapiensENSP0000035509491.202390.6158sus_scrofaENSSSCP0000005438895.987795.3704
ENSG00000112531homo_sapiensENSP0000035509499.120298.827microcebus_murinusENSMICP0000003570598.830498.538
ENSG00000112531homo_sapiensENSP00000355094100100octodon_degusENSODEP00000009905100100
ENSG00000112531homo_sapiensENSP0000035509480.351979.1789jaculus_jaculusENSJJAP0000002283292.881491.5254
ENSG00000112531homo_sapiensENSP00000355094100100ovis_aries_rambouilletENSOARP00020034070100100
ENSG00000112531homo_sapiensENSP0000035509491.202389.7361ursus_maritimusENSUMAP0000001586794.242492.7273
ENSG00000112531homo_sapiensENSP0000035509485.630585.044ochotona_princepsENSOPRP0000001063399.658798.9761
ENSG00000112531homo_sapiensENSP0000035509499.706799.4135delphinapterus_leucasENSDLEP0000001939499.706799.4135
ENSG00000112531homo_sapiensENSP0000035509499.706799.4135physeter_catodonENSPCTP0000500339799.706799.4135
ENSG00000112531homo_sapiensENSP0000035509492.375491.7889mus_caroliMGP_CAROLIEiJ_P004269696.923196.3077
ENSG00000112531homo_sapiensENSP00000355094100100mus_musculusENSMUSP00000156511100100
ENSG00000112531homo_sapiensENSP0000035509489.149687.39dipodomys_ordiiENSDORP0000000764694.70492.8349
ENSG00000112531homo_sapiensENSP0000035509483.87183.871mustela_putorius_furoENSMPUP00000006314100100
ENSG00000112531homo_sapiensENSP0000035509499.120298.827aotus_nancymaaeENSANAP0000002413798.830498.538
ENSG00000112531homo_sapiensENSP0000035509487.683385.044saimiri_boliviensis_boliviensisENSSBOP0000004059760.526358.7045
ENSG00000112531homo_sapiensENSP0000035509485.923885.9238vicugna_pacosENSVPAP00000008902100100
ENSG00000112531homo_sapiensENSP0000035509498.533797.3607chlorocebus_sabaeusENSCSAP0000000844398.533797.3607
ENSG00000112531homo_sapiensENSP0000035509450.439949.5601tupaia_belangeriENSTBEP0000001461758.904157.8767
ENSG00000112531homo_sapiensENSP0000035509487.096885.3372mesocricetus_auratusENSMAUP0000000239298.019896.0396
ENSG00000112531homo_sapiensENSP0000035509499.413599.1202phocoena_sinusENSPSNP0000002091699.705999.4118
ENSG00000112531homo_sapiensENSP0000035509483.577781.2317camelus_dromedariusENSCDRP0000501451892.532589.9351
ENSG00000112531homo_sapiensENSP0000035509479.178978.2991carlito_syrichtaENSTSYP0000002479297.472996.3899
ENSG00000112531homo_sapiensENSP0000035509485.923885.6305panthera_tigris_altaicaENSPTIP0000000711685.923885.6305
ENSG00000112531homo_sapiensENSP0000035509499.120299.1202rattus_norvegicusENSRNOP0000003441398.830498.8304
ENSG00000112531homo_sapiensENSP00000355094100100prolemur_simusENSPSMP00000007564100100
ENSG00000112531homo_sapiensENSP0000035509487.683386.217microtus_ochrogasterENSMOCP0000000838894.920693.3333
ENSG00000112531homo_sapiensENSP0000035509485.04485.044sorex_araneusENSSARP0000000980498.976198.9761
ENSG00000112531homo_sapiensENSP0000035509490.909189.1496peromyscus_maniculatus_bairdiiENSPEMP0000000531884.931583.2877
ENSG00000112531homo_sapiensENSP0000035509488.856387.9765bos_mutusENSBMUP0000003069697.427796.463
ENSG00000112531homo_sapiensENSP0000035509489.149688.563mus_spicilegusENSMSIP0000001660095.297894.6708
ENSG00000112531homo_sapiensENSP00000355094100100cricetulus_griseus_chok1gshdENSCGRP00001010156100100
ENSG00000112531homo_sapiensENSP0000035509471.847571.261pteropus_vampyrusENSPVAP0000001435283.617782.9352
ENSG00000112531homo_sapiensENSP0000035509485.923885.6305myotis_lucifugusENSMLUP0000000257097.019996.6887
ENSG00000112531homo_sapiensENSP0000035509499.706799.7067vombatus_ursinusENSVURP00010025118100100
ENSG00000112531homo_sapiensENSP0000035509499.706799.7067vombatus_ursinusENSVURP00010023919100100
ENSG00000112531homo_sapiensENSP00000355094100100rhinolophus_ferrumequinumENSRFEP00010012840100100
ENSG00000112531homo_sapiensENSP0000035509490.029388.8563neovison_visonENSNVIP0000002333194.461593.2308
ENSG00000112531homo_sapiensENSP00000355094100100bos_taurusENSBTAP00000048511100100
ENSG00000112531homo_sapiensENSP0000035509485.923884.1642heterocephalus_glaber_femaleENSHGLP0000005417091.277389.4081
ENSG00000112531homo_sapiensENSP0000035509499.120299.1202heterocephalus_glaber_femaleENSHGLP0000000419393.370293.3702
ENSG00000112531homo_sapiensENSP0000035509490.029388.2698rhinopithecus_bietiENSRBIP0000004048394.171892.3313
ENSG00000112531homo_sapiensENSP0000035509492.375491.7889canis_lupus_dingoENSCAFP0002002423696.923196.3077
ENSG00000112531homo_sapiensENSP00000355094100100sciurus_vulgarisENSSVLP00005013925100100
ENSG00000112531homo_sapiensENSP0000035509497.360797.3607phascolarctos_cinereusENSPCIP00000026995100100
ENSG00000112531homo_sapiensENSP0000035509446.334346.0411procavia_capensisENSPCAP0000000729954.861154.5139
ENSG00000112531homo_sapiensENSP0000035509487.976584.4575nannospalax_galiliENSNGAP0000000671294.936791.1392
ENSG00000112531homo_sapiensENSP0000035509465.102658.651bos_grunniensENSBGRP0000002465061.838455.7103
ENSG00000112531homo_sapiensENSP0000035509490.322687.9765chinchilla_lanigeraENSCLAP0000000893454.32152.9101
ENSG00000112531homo_sapiensENSP0000035509474.780170.6745chinchilla_lanigeraENSCLAP0000000390587.030782.2526
ENSG00000112531homo_sapiensENSP0000035509483.87183.871cervus_hanglu_yarkandensisENSCHYP00000039141100100
ENSG00000112531homo_sapiensENSP00000355094100100catagonus_wagneriENSCWAP00000025336100100
ENSG00000112531homo_sapiensENSP0000035509479.178978.2991ictidomys_tridecemlineatusENSSTOP0000000816997.472996.3899
ENSG00000112531homo_sapiensENSP00000355094100100otolemur_garnettiiENSOGAP00000003236100100
ENSG00000112531homo_sapiensENSP00000355094100100cebus_imitatorENSCCAP00000014849100100
ENSG00000112531homo_sapiensENSP00000355094100100urocitellus_parryiiENSUPAP00010014907100100
ENSG00000112531homo_sapiensENSP00000355094100100moschus_moschiferusENSMMSP00000004736100100
ENSG00000112531homo_sapiensENSP0000035509485.923885.9238rhinopithecus_roxellanaENSRROP0000003406185.923885.9238
ENSG00000112531homo_sapiensENSP00000355094100100mus_pahariMGP_PahariEiJ_P0054986100100
ENSG00000112531homo_sapiensENSP0000035509488.56388.563propithecus_coquereliENSPCOP00000002533100100
ENSG00000112531homo_sapiensENSP0000035509431.08517.5953drosophila_melanogasterFBpp030975621.544712.1951
ENSG00000112531homo_sapiensENSP0000035509430.498519.6481drosophila_melanogasterFBpp007175426.262616.9192
ENSG00000112531homo_sapiensENSP0000035509430.498517.8886drosophila_melanogasterFBpp007163332.601919.1223
ENSG00000112531homo_sapiensENSP0000035509434.310920.2346drosophila_melanogasterFBpp030388118.962711.1831
ENSG00000112531homo_sapiensENSP0000035509429.032317.5953drosophila_melanogasterFBpp007176436.666722.2222
ENSG00000112531homo_sapiensENSP0000035509431.08517.8886drosophila_melanogasterFBpp031160731.176517.9412
ENSG00000112531homo_sapiensENSP0000035509431.671619.0616drosophila_melanogasterFBpp030862134.069420.5047
ENSG00000112531homo_sapiensENSP0000035509429.618816.4223drosophila_melanogasterFBpp030861824.278813.4615
ENSG00000112531homo_sapiensENSP0000035509424.926718.4751eptatretus_burgeriENSEBUP0000000617851.204837.9518
ENSG00000112531homo_sapiensENSP0000035509488.56385.6305callorhinchus_miliiENSCMIP0000000862987.790784.8837
ENSG00000112531homo_sapiensENSP0000035509472.727371.261latimeria_chalumnaeENSLACP0000001769485.517283.7931
ENSG00000112531homo_sapiensENSP0000035509497.360796.1877lepisosteus_oculatusENSLOCP0000002039484.693983.6735
ENSG00000112531homo_sapiensENSP0000035509489.442882.9912clupea_harengusENSCHAP0000004543774.754969.3627
ENSG00000112531homo_sapiensENSP0000035509448.680443.4018clupea_harengusENSCHAP0000001651442.346937.7551
ENSG00000112531homo_sapiensENSP0000035509488.856385.9238danio_rerioENSDARP0000014830387.319984.438
ENSG00000112531homo_sapiensENSP0000035509490.029387.39carassius_auratusENSCARP0000002142682.085679.6791
ENSG00000112531homo_sapiensENSP0000035509488.856385.9238carassius_auratusENSCARP0000012280785.593282.7684
ENSG00000112531homo_sapiensENSP0000035509487.683385.6305astyanax_mexicanusENSAMXP0000001626693.146490.9657
ENSG00000112531homo_sapiensENSP0000035509489.149686.217ictalurus_punctatusENSIPUP0000001859087.356384.4828
ENSG00000112531homo_sapiensENSP0000035509488.56383.5777esox_luciusENSELUP0000007861888.304183.3333
ENSG00000112531homo_sapiensENSP0000035509477.126173.0205electrophorus_electricusENSEEEP0000002621379.939275.6839
ENSG00000112531homo_sapiensENSP0000035509487.976583.2845oncorhynchus_kisutchENSOKIP0000500602687.976583.2845
ENSG00000112531homo_sapiensENSP0000035509488.269883.5777oncorhynchus_kisutchENSOKIP0000500614188.011783.3333
ENSG00000112531homo_sapiensENSP0000035509492.375488.2698oncorhynchus_mykissENSOMYP0000014068488.235384.3137
ENSG00000112531homo_sapiensENSP0000035509488.269883.5777oncorhynchus_mykissENSOMYP0000006972288.269883.5777
ENSG00000112531homo_sapiensENSP0000035509488.269883.2845salmo_salarENSSSAP0000013624288.011783.0409
ENSG00000112531homo_sapiensENSP0000035509488.269883.2845salmo_salarENSSSAP0000016462988.269883.2845
ENSG00000112531homo_sapiensENSP0000035509479.472171.5543salmo_truttaENSSTUP0000003571481.381473.2733
ENSG00000112531homo_sapiensENSP0000035509488.269883.2845salmo_truttaENSSTUP0000003546888.269883.2845
ENSG00000112531homo_sapiensENSP0000035509485.630578.0059gadus_morhuaENSGMOP0000003310483.667676.2178
ENSG00000112531homo_sapiensENSP0000035509470.674564.2229fundulus_heteroclitusENSFHEP0000002651969.054462.7507
ENSG00000112531homo_sapiensENSP0000035509469.501562.4633poecilia_reticulataENSPREP0000001345566.949260.1695
ENSG00000112531homo_sapiensENSP0000035509470.381263.6364xiphophorus_maculatusENSXMAP0000004169768.965562.3563
ENSG00000112531homo_sapiensENSP0000035509469.794762.7566oryzias_latipesENSORLP0000003579268.194861.3181
ENSG00000112531homo_sapiensENSP0000035509462.463355.132cyclopterus_lumpusENSCLMP0000504750167.405159.4937
ENSG00000112531homo_sapiensENSP0000035509475.366668.915oreochromis_niloticusENSONIP0000006083079.076972.3077
ENSG00000112531homo_sapiensENSP0000035509483.284574.4868haplochromis_burtoniENSHBUP0000001399583.529474.7059
ENSG00000112531homo_sapiensENSP0000035509482.991274.1936astatotilapia_callipteraENSACLP0000001155182.507373.7609
ENSG00000112531homo_sapiensENSP0000035509481.524974.4868sparus_aurataENSSAUP0001005612981.764774.7059
ENSG00000112531homo_sapiensENSP0000035509482.991277.1261lates_calcariferENSLCAP0001003192387.345781.1728
ENSG00000112531homo_sapiensENSP0000035509488.269885.6305xenopus_tropicalisENSXETP0000006358783.84481.337
ENSG00000112531homo_sapiensENSP0000035509487.096885.9238chrysemys_picta_belliiENSCPBP0000002807392.523491.2773
ENSG00000112531homo_sapiensENSP0000035509499.120297.9472sphenodon_punctatusENSSPUP0000001579089.655288.5942
ENSG00000112531homo_sapiensENSP0000035509483.577783.5777crocodylus_porosusENSCPRP00005025357100100
ENSG00000112531homo_sapiensENSP0000035509497.360796.4809notechis_scutatusENSNSUP0000002062691.208890.3846
ENSG00000112531homo_sapiensENSP0000035509498.240597.9472pseudonaja_textilisENSPTXP0000001203894.101193.8202
ENSG00000112531homo_sapiensENSP0000035509499.413598.827anas_platyrhynchos_platyrhynchosENSAPLP0000002141099.705999.1176
ENSG00000112531homo_sapiensENSP0000035509499.413598.827gallus_gallusENSGALP0001000849399.705999.1176
ENSG00000112531homo_sapiensENSP0000035509487.3985.6305serinus_canariaENSSCAP0000002328695.512893.5897
ENSG00000112531homo_sapiensENSP0000035509497.947296.7742parus_majorENSPMJP0000000154297.660896.4912
ENSG00000112531homo_sapiensENSP0000035509497.65497.0675anolis_carolinensisENSACAP0000000320099.107198.5119
ENSG00000112531homo_sapiensENSP0000035509463.343157.1847neolamprologus_brichardiENSNBRP0000000969466.666760.1852
ENSG00000112531homo_sapiensENSP0000035509498.533798.2405naja_najaENSNNAP0000002004593.333393.0556
ENSG00000112531homo_sapiensENSP0000035509497.947297.0675podarcis_muralisENSPMRP0000000318496.811695.942
ENSG00000112531homo_sapiensENSP0000035509483.577783.2845geospiza_fortisENSGFOP0000000246210099.6491
ENSG00000112531homo_sapiensENSP0000035509469.208264.2229taeniopygia_guttataENSTGUP0000002200855.79251.773
ENSG00000112531homo_sapiensENSP0000035509491.788990.6158erpetoichthys_calabaricusENSECRP0000003059998.119196.8652
ENSG00000112531homo_sapiensENSP0000035509469.794763.3431kryptolebias_marmoratusENSKMAP000000120137063.5294
ENSG00000112531homo_sapiensENSP0000035509499.706799.4135salvator_merianaeENSSMRP0000002884310099.7059
ENSG00000112531homo_sapiensENSP0000035509469.501563.0499oryzias_javanicusENSOJAP0000004829767.908361.6046
ENSG00000112531homo_sapiensENSP0000035509457.47848.0938amphilophus_citrinellusENSACIP0000000519270.503658.9928
ENSG00000112531homo_sapiensENSP0000035509482.404774.4868dicentrarchus_labraxENSDLAP0000507932581.68673.8372
ENSG00000112531homo_sapiensENSP0000035509462.170157.1847amphiprion_perculaENSAPEP0000001153266.666761.3208
ENSG00000112531homo_sapiensENSP0000035509465.395958.651oryzias_sinensisENSOSIP0000000982645.417540.7332
ENSG00000112531homo_sapiensENSP0000035509499.706799.4135pelodiscus_sinensisENSPSIP0000001357210099.7059
ENSG00000112531homo_sapiensENSP0000035509499.706799.4135gopherus_evgoodeiENSGEVP0000501282510099.7059
ENSG00000112531homo_sapiensENSP0000035509499.706799.4135chelonoidis_abingdoniiENSCABP0000000643510099.7059
ENSG00000112531homo_sapiensENSP0000035509476.539670.6745seriola_dumeriliENSSDUP0000001812979.331373.2523
ENSG00000112531homo_sapiensENSP0000035509468.91559.824cottoperca_gobioENSCGOP0000003318067.335258.4527
ENSG00000112531homo_sapiensENSP0000035509463.343163.0499struthio_camelus_australisENSSCUP0000000135492.307791.8803
ENSG00000112531homo_sapiensENSP0000035509490.029388.2698anser_brachyrhynchusENSABRP0000000983795.638693.7695
ENSG00000112531homo_sapiensENSP0000035509468.91560.9971gasterosteus_aculeatusENSGACP0000000419962.169355.0265
ENSG00000112531homo_sapiensENSP0000035509464.516157.1847cynoglossus_semilaevisENSCSEP0000002110766.666759.0909
ENSG00000112531homo_sapiensENSP0000035509470.381263.9296poecilia_formosaENSPFOP0000001412168.767962.4642
ENSG00000112531homo_sapiensENSP0000035509487.3982.6979myripristis_murdjanENSMMDP0000501097685.142980.5714
ENSG00000112531homo_sapiensENSP0000035509479.765471.261sander_luciopercaENSSLUP0000001516483.435674.5399
ENSG00000112531homo_sapiensENSP0000035509497.360796.7742strigops_habroptilaENSSHBP0000502453110099.3976
ENSG00000112531homo_sapiensENSP000003550947.917897.03812amphiprion_ocellarisENSAOCP0000001669542.857138.0952
ENSG00000112531homo_sapiensENSP0000035509499.120298.827terrapene_carolina_triunguisENSTMTP0000000045999.411899.1176
ENSG00000112531homo_sapiensENSP0000035509488.269882.9912hucho_huchoENSHHUP0000005932588.269882.9912
ENSG00000112531homo_sapiensENSP0000035509488.269883.5777hucho_huchoENSHHUP0000006130488.269883.5777
ENSG00000112531homo_sapiensENSP0000035509470.08863.3431betta_splendensENSBSLP0000002963068.678262.069
ENSG00000112531homo_sapiensENSP0000035509480.351975.0733pygocentrus_nattereriENSPNAP0000002733582.282376.8769
ENSG00000112531homo_sapiensENSP0000035509485.04478.0059anabas_testudineusENSATEP0000003279085.04478.0059
ENSG00000112531homo_sapiensENSP0000035509473.60767.4487seriola_lalandi_dorsalisENSSLDP0000000156078.437571.875
ENSG00000112531homo_sapiensENSP0000035509475.366666.2757labrus_bergyltaENSLBEP0000003001975.366666.2757
ENSG00000112531homo_sapiensENSP0000035509464.222957.1847pundamilia_nyerereiENSPNYP0000000617667.592660.1852
ENSG00000112531homo_sapiensENSP0000035509483.577777.1261mastacembelus_armatusENSMAMP0000004086283.333376.9006
ENSG00000112531homo_sapiensENSP0000035509470.08863.3431stegastes_partitusENSSPAP0000000372668.678262.069
ENSG00000112531homo_sapiensENSP0000035509488.269883.871oncorhynchus_tshawytschaENSOTSP0000505830978.181874.2857
ENSG00000112531homo_sapiensENSP0000035509469.794763.3431acanthochromis_polyacanthusENSAPOP0000000142169.794763.3431
ENSG00000112531homo_sapiensENSP0000035509499.413598.827aquila_chrysaetos_chrysaetosENSACCP0002000197699.705999.1176
ENSG00000112531homo_sapiensENSP0000035509470.08863.6364nothobranchius_furzeriENSNFUP0001500978068.481462.1777
ENSG00000112531homo_sapiensENSP0000035509470.381263.6364cyprinodon_variegatusENSCVAP0000001151668.767962.1777
ENSG00000112531homo_sapiensENSP0000035509488.856386.5103denticeps_clupeoidesENSDCDP0000000697886.324884.0456
ENSG00000112531homo_sapiensENSP0000035509483.577775.6598larimichthys_croceaENSLCRP0000503922483.090475.2187
ENSG00000112531homo_sapiensENSP0000035509470.08862.4633takifugu_rubripesENSTRUP0000004620171.556963.7725
ENSG00000112531homo_sapiensENSP0000035509486.510384.4575ficedula_albicollisENSFALP0000002559996.091293.8111
ENSG00000112531homo_sapiensENSP0000035509468.91561.2903hippocampus_comesENSHCOP0000002534067.335259.8854
ENSG00000112531homo_sapiensENSP0000035509490.322687.6833cyprinus_carpio_carpioENSCCRP0000016821582.352979.9465
ENSG00000112531homo_sapiensENSP0000035509489.736186.5103cyprinus_carpio_carpioENSCCRP0000017412986.931883.8068
ENSG00000112531homo_sapiensENSP0000035509495.601294.7214coturnix_japonicaENSCJPP0000500443265.330764.7295
ENSG00000112531homo_sapiensENSP0000035509487.3984.7507coturnix_japonicaENSCJPP0000501151293.416990.5956
ENSG00000112531homo_sapiensENSP0000035509464.222957.7713poecilia_latipinnaENSPLAP0000001626569.303862.3418
ENSG00000112531homo_sapiensENSP0000035509478.005973.607sinocyclocheilus_grahamiENSSGRP0000009020781.595176.9939
ENSG00000112531homo_sapiensENSP0000035509489.442886.217sinocyclocheilus_grahamiENSSGRP0000001816189.181385.9649
ENSG00000112531homo_sapiensENSP0000035509482.991274.1936maylandia_zebraENSMZEP0000502456082.507373.7609
ENSG00000112531homo_sapiensENSP0000035509470.674563.3431tetraodon_nigroviridisENSTNIP0000001403471.091463.7168
ENSG00000112531homo_sapiensENSP0000035509479.178976.2463paramormyrops_kingsleyaeENSPKIP0000001647288.235384.9673
ENSG00000112531homo_sapiensENSP0000035509490.322687.6833scleropages_formosusENSSFOP000150754768885.4286
ENSG00000112531homo_sapiensENSP0000035509495.601292.6686leptobrachium_leishanenseENSLLEP0000002344382.323279.798
ENSG00000112531homo_sapiensENSP0000035509466.862257.1847scophthalmus_maximusENSSMAP0000004278054.028446.2085
ENSG00000112531homo_sapiensENSP0000035509469.501562.7566oryzias_melastigmaENSOMEP0000000609667.908361.3181

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0001570involved_in vasculogenesis1IEAHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003729enables mRNA binding1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus1IBAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IEAHomo_sapiens(9606)Component
GO:0006397involved_in mRNA processing1IEAHomo_sapiens(9606)Process
GO:0006417involved_in regulation of translation1IEAHomo_sapiens(9606)Process
GO:0007286involved_in spermatid development1IEAHomo_sapiens(9606)Process
GO:0008380involved_in RNA splicing1IEAHomo_sapiens(9606)Process
GO:0010628involved_in positive regulation of gene expression1IEAHomo_sapiens(9606)Process
GO:0017124enables SH3 domain binding1IEAHomo_sapiens(9606)Function
GO:0035886involved_in vascular associated smooth muscle cell differentiation1IEAHomo_sapiens(9606)Process
GO:0042552involved_in myelination1IEAHomo_sapiens(9606)Process
GO:0042759involved_in long-chain fatty acid biosynthetic process1IEAHomo_sapiens(9606)Process
GO:0045202located_in synapse1IEAHomo_sapiens(9606)Component
GO:0048024involved_in regulation of mRNA splicing, via spliceosome1IBAHomo_sapiens(9606)Process
GO:0051028involved_in mRNA transport1IEAHomo_sapiens(9606)Process

Expression