Ensembl ID ENSG00000112531 Gene ID 9444 Accession 21100
Gene Symbol QKI Alias QK;Hqk;QK1;QK3;hqkI Full Name QKI, KH domain containing RNA binding
Position 6 : 163414000 - 163578592 Length 164593 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary The protein encoded by this gene is an RNA-binding protein that regulates pre-mRNA splicing, export of mRNAs from the nucleus, protein translation, and mRNA stability. The encoded protein is involved in myelinization and oligodendrocyte differentiation and may play a role in schizophrenia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

ENSG00000112531 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000112531 QKI -1.2 9.86e-67 BRCA
ENSG00000112531 QKI -1.2 1.53e-54 LUSC
ENSG00000112531 QKI -1.1 4.48e-18 UCEC
ENSG00000112531 QKI -1.3 3.40e-50 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000112531 QKI tumor 11856480
ENSG00000112531 QKI cancer 16041388
ENSG00000112531 QKI colon cancer 19686745
ENSG00000112531 QKI cancer 21844227
ENSG00000112531 QKI tumor 22355603
ENSG00000112531 QKI cancer 22398723
ENSG00000112531 QKI tumours 22490519
ENSG00000112531 QKI cancer 22569043
ENSG00000112531 QKI cancer 22751500
ENSG00000112531 QKI cancers 23440637
ENSG00000112531 QKI prostate cancer 24153116
ENSG00000112531 QKI ovarian tumors 24335142
ENSG00000112531 QKI breast cancer 24398626
ENSG00000112531 QKI lung cancer 24722255
ENSG00000112531 QKI tumor 24799664
ENSG00000112531 QKI oral cancer 24918581
ENSG00000112531 QKI colon cancer 25420938
ENSG00000112531 QKI oral cancer 25457822
ENSG00000112531 QKI tumor 25578962
ENSG00000112531 QKI Lung Cancer 25630614
ENSG00000112531 QKI cancer 25908786
ENSG00000112531 QKI breast cancer 25913416
ENSG00000112531 QKI tumor 25971746
ENSG00000112531 QKI tumors 26337206
ENSG00000112531 QKI tumor 26829751
ENSG00000112531 QKI cancer 26991871
ENSG00000112531 QKI cervical cancer 27049079
ENSG00000112531 QKI tumor 27092877
ENSG00000112531 QKI cancer 27337969
ENSG00000112531 QKI tumor 27358073
ENSG00000112531 QKI tumor 27402815
ENSG00000112531 QKI lung cancer 27555542
ENSG00000112531 QKI kidney cancer 27767378
ENSG00000112531 QKI tumor 28179294
ENSG00000112531 QKI tumor 28212562
ENSG00000112531 QKI brain tumors 28597942
ENSG00000112531 QKI tumors 28806393
ENSG00000112531 QKI cancer 28969093
ENSG00000112531 QKI lung cancer 28991235
ENSG00000112531 QKI tumors 29064439
ENSG00000112531 QKI tumor 29137254
ENSG00000112531 QKI cancer 29387208
ENSG00000112531 QKI thyroid cancer 29556311
ENSG00000112531 QKI tumor 29654229
ENSG00000112531 QKI tumor 29658587
ENSG00000112531 QKI tumor 29861871
ENSG00000112531 QKI breast cancer 29871889
ENSG00000112531 QKI tumor 30059005
ENSG00000112531 QKI cancer 30277515
ENSG00000112531 QKI tumors 30279357
ENSG00000112531 QKI GBM 30400822
ENSG00000112531 QKI tumor 30517658
ENSG00000112531 QKI prostate cancer 30565858
ENSG00000112531 QKI cancer 30566575
ENSG00000112531 QKI cancers 30614793
ENSG00000112531 QKI tumour 30717751
ENSG00000112531 QKI cancer 30719845
ENSG00000112531 QKI tumor 30918328
ENSG00000112531 QKI pancreatic cancer 30968977
ENSG00000112531 QKI tumor 31026342
ENSG00000112531 QKI cancer 31096699
ENSG00000112531 QKI lung cancer 31152916
ENSG00000112531 QKI prostate cancer 31164793
ENSG00000112531 QKI tumors 31289476
ENSG00000112531 QKI GBM 31292920
ENSG00000112531 QKI Colorectal Cancer 31416845
ENSG00000112531 QKI tumor 31440515
ENSG00000112531 QKI cancer 31446897
ENSG00000112531 QKI tumour 31449345
ENSG00000112531 QKI tumor 31595628
ENSG00000112531 QKI cervical cancer 31786621
ENSG00000112531 QKI cervical cancer 31896069
ENSG00000112531 QKI breast cancer 31934023
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
ENSG00000112531 QKI colorectal adenocarcinoma frameshift_variant 6.415% (73/1138) 2 entries
ENSG00000112531 QKI colorectal adenocarcinoma sequence_alteration 6.415% (73/1138) 2 entries
ENSG00000112531 QKI prostate adenocarcinoma missense_variant 5.089% (74/1454) 1 entry
ENSG00000112531 QKI astrocytoma gene_fusion 42.86% (6/14) 1 entry
ENSG00000112531 QKI HER2 Positive Breast Carcinoma sequence_alteration 12.96% (14/108) 1 entry
ENSG00000112531 QKI colorectal adenocarcinoma missense_variant 6.415% (73/1138) 2 entries
ENSG00000112531 QKI breast ductal adenocarcinoma sequence_alteration 11.68% (77/659) 1 entry
ENSG00000112531 QKI colorectal adenocarcinoma stop_gained 6.415% (73/1138) 2 entries
ENSG00000112531 QKI skin melanoma stop_gained 0.4137% (4/967) 1 entry
ENSG00000112531 QKI brain glioblastoma missense_variant 1.187% (11/927) 2 entries
ENSG00000112531 QKI lobular breast carcinoma sequence_alteration 3.333% (2/60) 1 entry
ENSG00000112531 QKI squamous cell lung carcinoma sequence_alteration 0.9186% (7/762) 1 entry
ENSG00000112531 QKI diffuse gastric adenocarcinoma missense_variant 2.532% (2/79) 2 entries
ENSG00000112531 QKI clear cell renal carcinoma sequence_alteration 0.2326% (3/1290) 1 entry
ENSG00000112531 QKI colon adenocarcinoma stop_gained 4.33% (32/739) 4 entries
ENSG00000112531 QKI prostate carcinoma sequence_alteration 2.582% (11/426) 1 entry
ENSG00000112531 QKI colon adenocarcinoma missense_variant 4.33% (32/739) 5 entries
ENSG00000112531 QKI melanoma frameshift_variant 1.98% (2/101) 1 entry
ENSG00000112531 QKI gastric intestinal type adenocarcinoma frameshift_variant 3.529% (3/85) 1 entry
ENSG00000112531 QKI lung adenocarcinoma missense_variant 0.5159% (6/1163) 2 entries
ENSG00000112531 QKI nasopharyngeal squamous cell carcinoma missense_variant 1.198% (2/167) 2 entries
ENSG00000112531 QKI breast carcinoma sequence_alteration 0.198% (3/1515) 1 entry
ENSG00000112531 QKI brain glioblastoma sequence_alteration 1.187% (11/927) 1 entry
ENSG00000112531 QKI central nervous system primitive neuroectodermal neoplasm sequence_alteration 1.577% (7/444) 1 entry
ENSG00000112531 QKI colon adenocarcinoma sequence_alteration 4.33% (32/739) 5 entries
ENSG00000112531 QKI small cell lung carcinoma missense_variant 0.6289% (2/318) 1 entry
ENSG00000112531 QKI gastric adenocarcinoma missense_variant 1.254% (7/558) 1 entry
ENSG00000112531 QKI lung adenocarcinoma sequence_alteration 0.5159% (6/1163) 2 entries
ENSG00000112531 QKI cecum adenocarcinoma frameshift_variant 7.143% (9/126) 1 entry
ENSG00000112531 QKI gastric adenocarcinoma sequence_alteration 1.254% (7/558) 1 entry
ENSG00000112531 QKI esophageal adenocarcinoma frameshift_variant 19.18% (84/438) 1 entry
ENSG00000112531 QKI colon adenocarcinoma frameshift_variant 4.33% (32/739) 3 entries
ENSG00000112531 QKI cecum adenocarcinoma missense_variant 7.143% (9/126) 1 entry
ENSG00000112531 QKI basal cell carcinoma sequence_alteration 1.724% (1/58) 1 entry
ENSG00000112531 QKI Cortisol-Producing Adrenal Cortex Adenoma missense_variant 0.8065% (1/124) 1 entry
ENSG00000112531 QKI lobular breast carcinoma frameshift_variant 3.333% (2/60) 1 entry
ENSG00000112531 QKI oral squamous cell carcinoma missense_variant 0.4878% (1/205) 1 entry
ENSG00000112531 QKI gastric intestinal type adenocarcinoma sequence_alteration 3.529% (3/85) 1 entry
ENSG00000112531 QKI female breast carcinoma frameshift_variant 1.124% (3/267) 1 entry
ENSG00000112531 QKI gastric intestinal type adenocarcinoma missense_variant 3.529% (3/85) 1 entry
ENSG00000112531 QKI diffuse gastric adenocarcinoma sequence_alteration 2.532% (2/79) 1 entry
ENSG00000112531 QKI Pancreatic Acinar Cell Carcinoma frameshift_variant 5.0% (1/20) 1 entry
ENSG00000112531 QKI gastric adenocarcinoma frameshift_variant 1.254% (7/558) 1 entry
ENSG00000112531 QKI Brain Stem Glioblastoma missense_variant 1.786% (1/56) 1 entry
ENSG00000112531 QKI Brain Stem Glioblastoma sequence_alteration 1.786% (1/56) 1 entry
ENSG00000112531 QKI cecum adenocarcinoma stop_gained 7.143% (9/126) 1 entry
ENSG00000112531 QKI prostate carcinoma stop_gained 2.582% (11/426) 1 entry
ENSG00000112531 QKI lung adenocarcinoma stop_gained 0.5159% (6/1163) 1 entry
ENSG00000112531 QKI cervical carcinoma missense_variant 4.762% (1/21) 1 entry
ENSG00000112531 QKI Merkel cell skin cancer sequence_alteration 3.333% (1/30) 1 entry
ENSG00000112531 QKI non-small cell lung carcinoma missense_variant 1.613% (1/62) 1 entry
ENSG00000112531 QKI nasopharyngeal squamous cell carcinoma sequence_alteration 1.198% (2/167) 1 entry
ENSG00000112531 QKI Breast Carcinoma by Gene Expression Profile missense_variant 5.263% (1/19) 1 entry
ENSG00000112531 QKI ependymoma sequence_alteration 2.174% (1/46) 1 entry
ENSG00000112531 QKI embryonal rhabdomyosarcoma sequence_alteration 1.316% (1/76) 1 entry
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000112531 QKI MESO 0.012 high
ENSG00000112531 QKI STAD 0.00049 high
ENSG00000112531 QKI UCEC 0.0079 high
ENSG00000112531 QKI ACC 0.0091 high
ENSG00000112531 QKI LGG 0.012 low
ENSG00000112531 QKI READ 0.023 low
ENSG00000112531 QKI KIRP 0.0013 high
ENSG00000112531 QKI LUAD 0.016 low
ENSG00000112531 QKI THYM 0.014 low
ENSG00000112531 QKI UCS 0.043 low
ENSG00000112531 QKI ESCA 0.05 high
ENSG00000112531 QKI OV 0.0013 high
ENSG00000112531 QKI KIRC 0.0025 low
ENSG00000112531 QKI BLCA 0.017 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000112531 QKI CHOL Del 0.840293 0.216530 0.669395 0.694444
ENSG00000112531 QKI LUAD Del 2.020718 0.067561 0.381098 0.500000
ENSG00000112531 QKI LGG Del 2.649486 0.057826 0.576297 0.163743
ENSG00000112531 QKI CESC Del 2.899602 0.104228 0.486656 0.335593
ENSG00000112531 QKI ACC Del 0.845401 0.104656 0.523356 0.222222
ENSG00000112531 QKI GBM Del 33.331929 0.235293 0.607782 0.301560
ENSG00000112531 QKI SKCM Del 6.890042 0.141895 0.561404 0.599455
ENSG00000112531 QKI LIHC Del 7.739928 0.147474 0.621079 0.378378
ENSG00000112531 QKI BLCA Del 1.791970 0.095263 0.378156 0.465686
ENSG00000112531 QKI BRCA Del 15.483072 0.134329 0.484489 0.347222
ENSG00000112531 QKI STAD Del 1.139405 0.067021 0.350191 0.210884
ENSG00000112531 QKI UCEC Del 1.127048 0.053630 0.474411 0.087199
ENSG00000112531 QKI MESO Del 0.676679 0.121954 0.549998 0.367816
ENSG00000112531 QKI KIRC Del 10.128488 0.067050 0.461334 0.284091
ENSG00000112531 QKI UVM Del 0.757386 0.058192 0.824381 0.300000
ENSG00000112531 QKI OV Del 35.594868 0.484481 0.664451 0.649396