Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000111361 Gene ID 1967 Accession 3257
Symbol EIF2B1 Alias VWM1;EIF2B;EIF2BA;EIF2Balpha Full Name eukaryotic translation initiation factor 2B subunit alpha
Status Confidence Length 13361 bases Strand Minus strand
Position 12 : 123620406 - 123633766 RNA binding domain IF-2B
Summary This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Oct 2009]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000416250 IF-2B PF01008 3.2e-81 1
ENSP00000438060 IF-2B PF01008 3.6e-39 1
ENSP00000444183 IF-2B PF01008 1.4e-29 1
ENSP00000443172 IF-2B PF01008 1.4e-12 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
EIF2B1-201 ENST00000424014 2397 305aa ENSP00000416250
EIF2B1-205 ENST00000539951 848 202aa ENSP00000438060
EIF2B1-203 ENST00000534960 618 152aa ENSP00000443172
EIF2B1-204 ENST00000537073 1768 222aa ENSP00000444183
EIF2B1-202 ENST00000452159 622 No protein -
EIF2B1-206 ENST00000543940 423 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000111361homo_sapiensENSP0000004066330.623319.2412homo_sapiensENSP0000041625037.049223.2787
ENSG00000111361homo_sapiensENSP0000023355228.298315.6788homo_sapiensENSP0000041625048.524626.8852
ENSG00000111361homo_sapiensENSP0000026612634.472921.9373homo_sapiensENSP0000041625039.672125.2459

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000111361homo_sapiensENSP00000416250100100nomascus_leucogenysENSNLEP00000048835100100
ENSG00000111361homo_sapiensENSP0000041625099.672198.6885pan_paniscusENSPPAP0000000626499.346498.366
ENSG00000111361homo_sapiensENSP00000416250100100pongo_abeliiENSPPYP00000039427100100
ENSG00000111361homo_sapiensENSP0000041625099.672198.6885pan_troglodytesENSPTRP0000000952799.346498.366
ENSG00000111361homo_sapiensENSP0000041625099.672199.0164gorilla_gorillaENSGGOP0000000895799.346498.6928
ENSG00000111361homo_sapiensENSP0000041625095.409890.8197ornithorhynchus_anatinusENSOANP0000002412495.409890.8197
ENSG00000111361homo_sapiensENSP0000041625093.442690.8197sarcophilus_harrisiiENSSHAP0000001868693.442690.8197
ENSG00000111361homo_sapiensENSP0000041625085.245982.9508notamacropus_eugeniiENSMEUP0000001251486.666784.3333
ENSG00000111361homo_sapiensENSP0000041625098.688597.3771choloepus_hoffmanniENSCHOP0000000549098.688597.3771
ENSG00000111361homo_sapiensENSP0000041625097.377195.082dasypus_novemcinctusENSDNOP0000000401697.377195.082
ENSG00000111361homo_sapiensENSP0000041625089.180386.5574erinaceus_europaeusENSEEUP0000000601689.473786.8421
ENSG00000111361homo_sapiensENSP0000041625060.655758.6885echinops_telfairiENSETEP0000000148288.095285.2381
ENSG00000111361homo_sapiensENSP0000041625099.016498.6885callithrix_jacchusENSCJAP0000003807499.016498.6885
ENSG00000111361homo_sapiensENSP0000041625099.016498.3607cercocebus_atysENSCATP0000001877798.692898.0392
ENSG00000111361homo_sapiensENSP0000041625099.344399.3443macaca_fascicularisENSMFAP0000004554598.697198.6971
ENSG00000111361homo_sapiensENSP0000041625099.344399.3443macaca_mulattaENSMMUP0000001731399.344399.3443
ENSG00000111361homo_sapiensENSP0000041625099.016498.0328macaca_nemestrinaENSMNEP0000004038398.692897.7124
ENSG00000111361homo_sapiensENSP0000041625099.344399.3443papio_anubisENSPANP0000000854399.344399.3443
ENSG00000111361homo_sapiensENSP0000041625099.016498.3607mandrillus_leucophaeusENSMLEP0000000424198.692898.0392
ENSG00000111361homo_sapiensENSP0000041625090.491888.1967tursiops_truncatusENSTTRP0000000686690.491888.1967
ENSG00000111361homo_sapiensENSP0000041625097.377196.3934vulpes_vulpesENSVVUP0000003856097.377196.3934
ENSG00000111361homo_sapiensENSP0000041625096.721393.7705mus_spretusMGP_SPRETEiJ_P007359896.721393.7705
ENSG00000111361homo_sapiensENSP0000041625097.377195.082equus_asinusENSEASP0000505095397.377195.082
ENSG00000111361homo_sapiensENSP0000041625098.032895.4098capra_hircusENSCHIP0000001418698.032895.4098
ENSG00000111361homo_sapiensENSP0000041625054.426248.8525capra_hircusENSCHIP0000001069376.851968.9815
ENSG00000111361homo_sapiensENSP0000041625095.737793.1148loxodonta_africanaENSLAFP0000000613297.0194.3522
ENSG00000111361homo_sapiensENSP0000041625097.704997.0492panthera_leoENSPLOP0000002084774.874474.3719
ENSG00000111361homo_sapiensENSP0000041625095.08293.4426ailuropoda_melanoleucaENSAMEP0000003298372.864371.608
ENSG00000111361homo_sapiensENSP0000041625097.704995.082bos_indicus_hybridENSBIXP0000503642297.704995.082
ENSG00000111361homo_sapiensENSP0000041625097.704996.0656oryctolagus_cuniculusENSOCUP0000000300385.87984.438
ENSG00000111361homo_sapiensENSP0000041625097.377195.4098equus_caballusENSECAP0000001892497.377195.4098
ENSG00000111361homo_sapiensENSP0000041625097.377196.3934canis_lupus_familiarisENSCAFP0084502379597.377196.3934
ENSG00000111361homo_sapiensENSP0000041625097.704997.0492panthera_pardusENSPPRP0000001958097.704997.0492
ENSG00000111361homo_sapiensENSP0000041625098.360795.7377marmota_marmota_marmotaENSMMMP0000002809698.360795.7377
ENSG00000111361homo_sapiensENSP0000041625098.032895.082balaenoptera_musculusENSBMSP0001003016898.032895.082
ENSG00000111361homo_sapiensENSP0000041625097.377195.4098cavia_porcellusENSCPOP0000003116897.377195.4098
ENSG00000111361homo_sapiensENSP0000041625097.704997.0492felis_catusENSFCAP0000004023166.517966.0714
ENSG00000111361homo_sapiensENSP0000041625095.08293.4426ursus_americanusENSUAMP0000001572795.08293.4426
ENSG00000111361homo_sapiensENSP0000041625093.770591.1475monodelphis_domesticaENSMODP0000005202893.770591.1475
ENSG00000111361homo_sapiensENSP0000041625097.377194.7541bison_bison_bisonENSBBBP0000001063697.377194.7541
ENSG00000111361homo_sapiensENSP0000041625097.704995.082monodon_monocerosENSMMNP0001501946797.704995.082
ENSG00000111361homo_sapiensENSP0000041625057.049252.7869sus_scrofaENSSSCP0000007819181.690175.5869
ENSG00000111361homo_sapiensENSP0000041625097.704996.3934sus_scrofaENSSSCP0000003164197.704996.3934
ENSG00000111361homo_sapiensENSP0000041625098.360797.0492microcebus_murinusENSMICP0000004306598.360797.0492
ENSG00000111361homo_sapiensENSP0000041625096.721393.4426octodon_degusENSODEP0000002604996.721393.4426
ENSG00000111361homo_sapiensENSP0000041625097.049295.7377octodon_degusENSODEP0000001382997.368496.0526
ENSG00000111361homo_sapiensENSP0000041625093.114888.1967octodon_degusENSODEP0000002563393.114888.1967
ENSG00000111361homo_sapiensENSP0000041625098.360796.7213jaculus_jaculusENSJJAP0000001027598.360796.7213
ENSG00000111361homo_sapiensENSP0000041625098.032895.082ovis_aries_rambouilletENSOARP0002000786598.032895.082
ENSG00000111361homo_sapiensENSP0000041625095.08293.4426ursus_maritimusENSUMAP0000000481395.08293.4426
ENSG00000111361homo_sapiensENSP0000041625097.377193.4426ochotona_princepsENSOPRP0000000079197.058893.1373
ENSG00000111361homo_sapiensENSP0000041625096.065693.4426delphinapterus_leucasENSDLEP0000001889096.381693.75
ENSG00000111361homo_sapiensENSP0000041625098.032895.4098physeter_catodonENSPCTP0000502863698.032895.4098
ENSG00000111361homo_sapiensENSP0000041625096.721393.7705mus_caroliMGP_CAROLIEiJ_P007088996.721393.7705
ENSG00000111361homo_sapiensENSP0000041625096.721394.0984mus_musculusENSMUSP0000003133496.721394.0984
ENSG00000111361homo_sapiensENSP0000041625096.393495.082dipodomys_ordiiENSDORP000000028549896.6667
ENSG00000111361homo_sapiensENSP0000041625096.393493.4426mustela_putorius_furoENSMPUP0000000148596.393493.4426
ENSG00000111361homo_sapiensENSP0000041625099.344398.6885aotus_nancymaaeENSANAP0000001923399.344398.6885
ENSG00000111361homo_sapiensENSP0000041625099.016498.0328saimiri_boliviensis_boliviensisENSSBOP0000002886398.692897.7124
ENSG00000111361homo_sapiensENSP0000041625097.377195.4098vicugna_pacosENSVPAP0000000653897.377195.4098
ENSG00000111361homo_sapiensENSP0000041625099.344399.3443chlorocebus_sabaeusENSCSAP0000001597799.344399.3443
ENSG00000111361homo_sapiensENSP0000041625082.950882.2951tupaia_belangeriENSTBEP0000000941783.223782.5658
ENSG00000111361homo_sapiensENSP0000041625097.704996.0656mesocricetus_auratusENSMAUP0000002172597.704996.0656
ENSG00000111361homo_sapiensENSP0000041625097.704995.4098phocoena_sinusENSPSNP0000001590997.704995.4098
ENSG00000111361homo_sapiensENSP0000041625098.360796.0656camelus_dromedariusENSCDRP0000503284498.360796.0656
ENSG00000111361homo_sapiensENSP0000041625080.983678.0328carlito_syrichtaENSTSYP0000002687792.164288.806
ENSG00000111361homo_sapiensENSP0000041625098.688597.7049carlito_syrichtaENSTSYP0000001506898.688597.7049
ENSG00000111361homo_sapiensENSP0000041625097.704997.0492panthera_tigris_altaicaENSPTIP0000000800497.704997.0492
ENSG00000111361homo_sapiensENSP0000041625095.08292.459rattus_norvegicusENSRNOP0000007587095.08292.459
ENSG00000111361homo_sapiensENSP0000041625097.704995.4098prolemur_simusENSPSMP0000001889695.207792.9712
ENSG00000111361homo_sapiensENSP0000041625097.704995.4098microtus_ochrogasterENSMOCP0000001301197.704995.4098
ENSG00000111361homo_sapiensENSP0000041625058.360755.7377peromyscus_maniculatus_bairdiiENSPEMP0000003694882.027678.341
ENSG00000111361homo_sapiensENSP0000041625097.377194.4262peromyscus_maniculatus_bairdiiENSPEMP0000001564097.377194.4262
ENSG00000111361homo_sapiensENSP0000041625097.704995.082bos_mutusENSBMUP0000001775197.704995.082
ENSG00000111361homo_sapiensENSP0000041625097.049294.0984mus_spicilegusENSMSIP0000000990679.569977.1505
ENSG00000111361homo_sapiensENSP0000041625097.377195.7377cricetulus_griseus_chok1gshdENSCGRP0000102410097.377195.7377
ENSG00000111361homo_sapiensENSP0000041625098.032896.7213pteropus_vampyrusENSPVAP0000001444698.032896.7213
ENSG00000111361homo_sapiensENSP0000041625058.032856.7213myotis_lucifugusENSMLUP0000000034597.252795.0549
ENSG00000111361homo_sapiensENSP0000041625077.377175.082myotis_lucifugusENSMLUP0000000672289.056686.4151
ENSG00000111361homo_sapiensENSP0000041625097.377195.7377myotis_lucifugusENSMLUP0000000116797.377195.7377
ENSG00000111361homo_sapiensENSP0000041625093.770590.1639vombatus_ursinusENSVURP0001000232593.770590.1639
ENSG00000111361homo_sapiensENSP0000041625097.704997.0492rhinolophus_ferrumequinumENSRFEP0001003121197.704997.0492
ENSG00000111361homo_sapiensENSP0000041625095.737793.4426neovison_visonENSNVIP0000002755496.052693.75
ENSG00000111361homo_sapiensENSP0000041625097.704995.082bos_taurusENSBTAP0000000956097.704995.082
ENSG00000111361homo_sapiensENSP0000041625098.032896.0656heterocephalus_glaber_femaleENSHGLP0000005479098.032896.0656
ENSG00000111361homo_sapiensENSP0000041625099.016497.7049rhinopithecus_bietiENSRBIP0000002278598.692897.3856
ENSG00000111361homo_sapiensENSP0000041625097.377196.3934canis_lupus_dingoENSCAFP0002001919497.377196.3934
ENSG00000111361homo_sapiensENSP0000041625098.032895.4098sciurus_vulgarisENSSVLP0000502167398.032895.4098
ENSG00000111361homo_sapiensENSP0000041625092.786989.8361phascolarctos_cinereusENSPCIP0000001402355.818554.0434
ENSG00000111361homo_sapiensENSP0000041625089.508288.5246procavia_capensisENSPCAP0000001326889.508288.5246
ENSG00000111361homo_sapiensENSP0000041625098.360796.7213nannospalax_galiliENSNGAP0000000257498.360796.7213
ENSG00000111361homo_sapiensENSP0000041625097.704995.082bos_grunniensENSBGRP0000002434997.704995.082
ENSG00000111361homo_sapiensENSP0000041625098.360797.0492chinchilla_lanigeraENSCLAP0000002134398.360797.0492
ENSG00000111361homo_sapiensENSP0000041625098.032895.4098cervus_hanglu_yarkandensisENSCHYP0000000309298.032895.4098
ENSG00000111361homo_sapiensENSP0000041625097.704995.7377catagonus_wagneriENSCWAP0000002288197.704995.7377
ENSG00000111361homo_sapiensENSP0000041625098.360796.0656ictidomys_tridecemlineatusENSSTOP0000000551098.360796.0656
ENSG00000111361homo_sapiensENSP0000041625098.360797.3771otolemur_garnettiiENSOGAP0000000824598.360797.3771
ENSG00000111361homo_sapiensENSP0000041625099.016498.6885cebus_imitatorENSCCAP0000003224198.371398.0456
ENSG00000111361homo_sapiensENSP0000041625098.360796.0656urocitellus_parryiiENSUPAP0001002359898.360796.0656
ENSG00000111361homo_sapiensENSP0000041625098.032895.4098moschus_moschiferusENSMMSP0000001116998.032895.4098
ENSG00000111361homo_sapiensENSP0000041625099.016498.0328rhinopithecus_roxellanaENSRROP0000000796698.692897.7124
ENSG00000111361homo_sapiensENSP0000041625097.049293.4426mus_pahariMGP_PahariEiJ_P005909897.049293.4426
ENSG00000111361homo_sapiensENSP0000041625098.360798.0328propithecus_coquereliENSPCOP0000001907298.360798.0328
ENSG00000111361homo_sapiensENSP0000041625062.295142.9508caenorhabditis_elegansZK1098.4.162.295142.9508
ENSG00000111361homo_sapiensENSP0000041625066.229549.5082drosophila_melanogasterFBpp008487466.013149.3464
ENSG00000111361homo_sapiensENSP0000041625076.393460.6557ciona_intestinalisENSCINP0000001285076.393460.6557
ENSG00000111361homo_sapiensENSP0000041625080.327965.5738petromyzon_marinusENSPMAP0000000398581.125866.2252
ENSG00000111361homo_sapiensENSP0000041625084.262370.4918eptatretus_burgeriENSEBUP0000001277576.946164.3713
ENSG00000111361homo_sapiensENSP0000041625086.229577.0492callorhinchus_miliiENSCMIP0000003373385.947776.7974
ENSG00000111361homo_sapiensENSP0000041625089.508280.9836latimeria_chalumnaeENSLACP0000001937087.579.1667
ENSG00000111361homo_sapiensENSP0000041625088.196780.3279lepisosteus_oculatusENSLOCP0000000708187.622179.8046
ENSG00000111361homo_sapiensENSP0000041625086.557475.7377clupea_harengusENSCHAP0000002655078.571468.75
ENSG00000111361homo_sapiensENSP0000041625083.606673.4426danio_rerioENSDARP0000000387587.628976.9759
ENSG00000111361homo_sapiensENSP0000041625087.54176.7213carassius_auratusENSCARP0000011846888.410677.4834
ENSG00000111361homo_sapiensENSP0000041625085.573875.7377carassius_auratusENSCARP0000000269675.216166.5706
ENSG00000111361homo_sapiensENSP0000041625087.213177.7049astyanax_mexicanusENSAMXP0000003978588.079578.4768
ENSG00000111361homo_sapiensENSP0000041625087.54177.7049ictalurus_punctatusENSIPUP0000003006088.410678.4768
ENSG00000111361homo_sapiensENSP0000041625087.54177.3771esox_luciusENSELUP0000005739575.423766.6667
ENSG00000111361homo_sapiensENSP0000041625087.213177.3771esox_luciusENSELUP0000006380987.788877.8878
ENSG00000111361homo_sapiensENSP0000041625086.885277.3771electrophorus_electricusENSEEEP0000004959479.104570.4478
ENSG00000111361homo_sapiensENSP0000041625073.114862.2951oncorhynchus_kisutchENSOKIP0000500956678.521166.9014
ENSG00000111361homo_sapiensENSP0000041625088.196779.0164oncorhynchus_kisutchENSOKIP0000500388280.059571.7262
ENSG00000111361homo_sapiensENSP0000041625087.54176.3934oncorhynchus_kisutchENSOKIP0000501277886.970775.8958
ENSG00000111361homo_sapiensENSP0000041625079.344368.1967oncorhynchus_mykissENSOMYP0000003856775.389464.7975
ENSG00000111361homo_sapiensENSP0000041625055.737750.1639oncorhynchus_mykissENSOMYP0000000437082.926874.6341
ENSG00000111361homo_sapiensENSP0000041625088.196776.7213oncorhynchus_mykissENSOMYP0000002569288.778977.2277
ENSG00000111361homo_sapiensENSP0000041625088.196778.6885salmo_salarENSSSAP0000001207281.024172.2892
ENSG00000111361homo_sapiensENSP0000041625088.196777.0492salmo_salarENSSSAP0000015510677.077467.3352
ENSG00000111361homo_sapiensENSP0000041625087.213177.7049salmo_salarENSSSAP0000010365987.577.9605
ENSG00000111361homo_sapiensENSP0000041625088.196777.0492salmo_truttaENSSTUP0000008613988.486877.3026
ENSG00000111361homo_sapiensENSP0000041625087.54177.7049salmo_truttaENSSTUP0000011075987.828977.9605
ENSG00000111361homo_sapiensENSP0000041625088.196779.6721salmo_truttaENSSTUP0000003850277.97170.4348
ENSG00000111361homo_sapiensENSP0000041625088.196778.6885gadus_morhuaENSGMOP0000003346083.281774.3034
ENSG00000111361homo_sapiensENSP0000041625089.508279.6721fundulus_heteroclitusENSFHEP0000000673690.397480.4636
ENSG00000111361homo_sapiensENSP0000041625089.836180poecilia_reticulataENSPREP0000002472082.779573.716
ENSG00000111361homo_sapiensENSP0000041625090.163980xiphophorus_maculatusENSXMAP0000002177091.059680.7947
ENSG00000111361homo_sapiensENSP0000041625088.196778.3607oryzias_latipesENSORLP0000000052089.072879.1391
ENSG00000111361homo_sapiensENSP0000041625090.163980.9836cyclopterus_lumpusENSCLMP0000503258691.059681.7881
ENSG00000111361homo_sapiensENSP0000041625089.836180.3279oreochromis_niloticusENSONIP0000005084983.282774.4681
ENSG00000111361homo_sapiensENSP0000041625089.836180.9836haplochromis_burtoniENSHBUP0000000992782.779574.6224
ENSG00000111361homo_sapiensENSP0000041625089.836180.9836astatotilapia_callipteraENSACLP0000003650090.728581.7881
ENSG00000111361homo_sapiensENSP0000041625088.524680sparus_aurataENSSAUP0001001543688.524680
ENSG00000111361homo_sapiensENSP0000041625089.508281.3115lates_calcariferENSLCAP0001002286382.727375.1515
ENSG00000111361homo_sapiensENSP0000041625086.885278.0328xenopus_tropicalisENSXETP0000007676087.748378.8079
ENSG00000111361homo_sapiensENSP0000041625093.442687.8689chrysemys_picta_belliiENSCPBP0000003748194.370988.7417
ENSG00000111361homo_sapiensENSP0000041625092.131186.5574sphenodon_punctatusENSSPUP0000001660093.046487.4172
ENSG00000111361homo_sapiensENSP0000041625090.819784.918crocodylus_porosusENSCPRP0000502592280.289975.0725
ENSG00000111361homo_sapiensENSP0000041625089.508281.9672laticauda_laticaudataENSLLTP0000001437459.60754.5852
ENSG00000111361homo_sapiensENSP0000041625090.163981.6393notechis_scutatusENSNSUP0000001570191.059682.4503
ENSG00000111361homo_sapiensENSP0000041625090.163981.6393pseudonaja_textilisENSPTXP0000001503091.059682.4503
ENSG00000111361homo_sapiensENSP0000041625091.803382.6229anas_platyrhynchos_platyrhynchosENSAPLP0000001462384.848576.3636
ENSG00000111361homo_sapiensENSP0000041625092.131182.2951gallus_gallusENSGALP0001003705593.046483.1126
ENSG00000111361homo_sapiensENSP0000041625081.311574.0984meleagris_gallopavoENSMGAP0000000284792.883984.6442
ENSG00000111361homo_sapiensENSP0000041625091.803382.6229serinus_canariaENSSCAP0000001311092.715283.4437
ENSG00000111361homo_sapiensENSP0000041625091.475482.6229parus_majorENSPMJP0000000308972.467565.4545
ENSG00000111361homo_sapiensENSP0000041625089.180381.6393anolis_carolinensisENSACAP0000003470190.066282.4503
ENSG00000111361homo_sapiensENSP0000041625051.803345.2459neolamprologus_brichardiENSNBRP0000002460384.042673.4043
ENSG00000111361homo_sapiensENSP0000041625089.836181.9672naja_najaENSNNAP0000002244590.728582.7815
ENSG00000111361homo_sapiensENSP0000041625089.508281.6393podarcis_muralisENSPMRP0000002799490.397482.4503
ENSG00000111361homo_sapiensENSP0000041625075.409867.8689geospiza_fortisENSGFOP0000000742983.941675.5474
ENSG00000111361homo_sapiensENSP0000041625092.131181.9672taeniopygia_guttataENSTGUP0000000544793.046482.7815
ENSG00000111361homo_sapiensENSP0000041625088.196780.6557erpetoichthys_calabaricusENSECRP0000003162988.486880.9211
ENSG00000111361homo_sapiensENSP0000041625089.508279.0164kryptolebias_marmoratusENSKMAP0000002973983.231773.4756
ENSG00000111361homo_sapiensENSP0000041625089.836183.6066salvator_merianaeENSSMRP0000002389090.728584.4371
ENSG00000111361homo_sapiensENSP0000041625084.590276.7213oryzias_javanicusENSOJAP0000001234382.692375
ENSG00000111361homo_sapiensENSP0000041625088.196780.3279amphilophus_citrinellusENSACIP0000000972088.196780.3279
ENSG00000111361homo_sapiensENSP0000041625089.508280.3279dicentrarchus_labraxENSDLAP0000502649579.360571.2209
ENSG00000111361homo_sapiensENSP0000041625089.180379.6721amphiprion_perculaENSAPEP0000001559190.066280.4636
ENSG00000111361homo_sapiensENSP0000041625080.655776.7213pelodiscus_sinensisENSPSIP0000001880392.830288.3019
ENSG00000111361homo_sapiensENSP0000041625093.114888.1967gopherus_evgoodeiENSGEVP0000501809494.039789.0728
ENSG00000111361homo_sapiensENSP0000041625057.37751.8033chelonoidis_abingdoniiENSCABP0000001023292.105383.1579
ENSG00000111361homo_sapiensENSP0000041625089.180379.3443seriola_dumeriliENSSDUP0000003278584.210574.9226
ENSG00000111361homo_sapiensENSP0000041625089.180379.3443cottoperca_gobioENSCGOP0000005590583.692374.4615
ENSG00000111361homo_sapiensENSP0000041625074.754166.8852struthio_camelus_australisENSSCUP0000000510682.608773.913
ENSG00000111361homo_sapiensENSP0000041625092.131183.2787anser_brachyrhynchusENSABRP0000001039893.046484.106
ENSG00000111361homo_sapiensENSP0000041625087.868978.3607gasterosteus_aculeatusENSGACP0000002057888.741779.1391
ENSG00000111361homo_sapiensENSP0000041625090.163980cynoglossus_semilaevisENSCSEP0000001897391.059680.7947
ENSG00000111361homo_sapiensENSP0000041625089.508280poecilia_formosaENSPFOP0000000685690.397480.7947
ENSG00000111361homo_sapiensENSP0000041625089.836180myripristis_murdjanENSMMDP0000502278980.588271.7647
ENSG00000111361homo_sapiensENSP0000041625089.836180.6557sander_luciopercaENSSLUP0000004088580.82672.5664
ENSG00000111361homo_sapiensENSP0000041625091.147582.2951strigops_habroptilaENSSHBP0000501044592.05383.1126
ENSG00000111361homo_sapiensENSP0000041625089.180379.6721amphiprion_ocellarisENSAOCP0000000802390.066280.4636
ENSG00000111361homo_sapiensENSP0000041625093.770588.1967terrapene_carolina_triunguisENSTMTP0000002542094.70289.0728
ENSG00000111361homo_sapiensENSP0000041625085.901678.3607hucho_huchoENSHHUP0000008040276.608269.883
ENSG00000111361homo_sapiensENSP000004162508068.8525hucho_huchoENSHHUP0000004428678.205167.3077
ENSG00000111361homo_sapiensENSP0000041625087.868976.7213hucho_huchoENSHHUP0000004309588.448877.2277
ENSG00000111361homo_sapiensENSP0000041625087.868979.0164betta_splendensENSBSLP0000002506384.012575.5486
ENSG00000111361homo_sapiensENSP0000041625087.213178.3607pygocentrus_nattereriENSPNAP0000001429188.079579.1391
ENSG00000111361homo_sapiensENSP0000041625084.590275.4098anabas_testudineusENSATEP0000004815584.313775.1634
ENSG00000111361homo_sapiensENSP0000041625077.704963.6066ciona_savignyiENSCSAVP0000000976577.704963.6066
ENSG00000111361homo_sapiensENSP0000041625059.016442.2951saccharomyces_cerevisiaeYKR026C59.016442.2951
ENSG00000111361homo_sapiensENSP0000041625089.180380seriola_lalandi_dorsalisENSSLDP0000001420990.066280.7947
ENSG00000111361homo_sapiensENSP0000041625084.262378.6885labrus_bergyltaENSLBEP0000002878288.927383.045
ENSG00000111361homo_sapiensENSP0000041625089.836180.9836pundamilia_nyerereiENSPNYP0000000481990.728581.7881
ENSG00000111361homo_sapiensENSP0000041625088.196779.6721mastacembelus_armatusENSMAMP0000006558980.059572.3214
ENSG00000111361homo_sapiensENSP0000041625090.163980.9836stegastes_partitusENSSPAP0000001562291.059681.7881
ENSG00000111361homo_sapiensENSP0000041625075.409864.5902oncorhynchus_tshawytschaENSOTSP0000509520980.139468.6411
ENSG00000111361homo_sapiensENSP0000041625088.196776.7213oncorhynchus_tshawytschaENSOTSP0000506137087.908576.4706
ENSG00000111361homo_sapiensENSP0000041625074.426263.9344oncorhynchus_tshawytschaENSOTSP0000509415180.782969.395
ENSG00000111361homo_sapiensENSP000004162508071.8033oncorhynchus_tshawytschaENSOTSP0000509074974.846667.1779
ENSG00000111361homo_sapiensENSP0000041625088.852579.3443acanthochromis_polyacanthusENSAPOP0000002806789.735180.1325
ENSG00000111361homo_sapiensENSP0000041625092.131182.6229aquila_chrysaetos_chrysaetosENSACCP0002001115893.046483.4437
ENSG00000111361homo_sapiensENSP0000041625087.868979.0164nothobranchius_furzeriENSNFUP0001501323977.011569.2529
ENSG00000111361homo_sapiensENSP0000041625090.163980.3279cyprinodon_variegatusENSCVAP0000000528291.059681.1258
ENSG00000111361homo_sapiensENSP0000041625085.573874.4262denticeps_clupeoidesENSDCDP0000000529486.138674.9175
ENSG00000111361homo_sapiensENSP0000041625089.180379.0164larimichthys_croceaENSLCRP0000506092080.23671.0914
ENSG00000111361homo_sapiensENSP0000041625089.180379.3443takifugu_rubripesENSTRUP0000008453986.349276.8254
ENSG00000111361homo_sapiensENSP0000041625091.475482.2951ficedula_albicollisENSFALP0000003215492.384183.1126
ENSG00000111361homo_sapiensENSP0000041625087.868976.3934hippocampus_comesENSHCOP0000000334888.741777.1523
ENSG00000111361homo_sapiensENSP0000041625086.557475.7377cyprinus_carpio_carpioENSCCRP0000013918487.417276.4901
ENSG00000111361homo_sapiensENSP0000041625087.54177.0492cyprinus_carpio_carpioENSCCRP0000016042381.402471.6463
ENSG00000111361homo_sapiensENSP0000041625092.131182.2951coturnix_japonicaENSCJPP0000502535593.046483.1126
ENSG00000111361homo_sapiensENSP0000041625089.508280poecilia_latipinnaENSPLAP0000002674190.397480.7947
ENSG00000111361homo_sapiensENSP0000041625068.524657.0492sinocyclocheilus_grahamiENSSGRP0000007266572.569460.4167
ENSG00000111361homo_sapiensENSP0000041625069.180361.6393sinocyclocheilus_grahamiENSSGRP0000005789984.475.2
ENSG00000111361homo_sapiensENSP0000041625089.836180.9836maylandia_zebraENSMZEP0000501067890.728581.7881
ENSG00000111361homo_sapiensENSP0000041625087.54178.6885tetraodon_nigroviridisENSTNIP0000001650988.410679.4702
ENSG00000111361homo_sapiensENSP0000041625089.508280paramormyrops_kingsleyaeENSPKIP0000000798590.397480.7947
ENSG00000111361homo_sapiensENSP0000041625089.508277.7049scleropages_formosusENSSFOP0001506310588.064576.4516
ENSG00000111361homo_sapiensENSP0000041625086.885276.7213leptobrachium_leishanenseENSLLEP0000000565973.611165
ENSG00000111361homo_sapiensENSP0000041625088.852578.6885scophthalmus_maximusENSSMAP0000004975479.472170.3812
ENSG00000111361homo_sapiensENSP0000041625073.114865.9016oryzias_melastigmaENSOMEP0000002397190.283481.3765

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003743contributes_to translation initiation factor activity2IBA,IDAHomo_sapiens(9606)Function
GO:0005085contributes_to guanyl-nucleotide exchange factor activity2IBA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0005851part_of eukaryotic translation initiation factor 2B complex2IBA,IDAHomo_sapiens(9606)Component
GO:0005886located_in plasma membrane1IDAHomo_sapiens(9606)Component
GO:0006413involved_in translational initiation2IBA,IDAHomo_sapiens(9606)Process
GO:0009408involved_in response to heat2ISS,TASHomo_sapiens(9606)Process
GO:0009749involved_in response to glucose1ISSHomo_sapiens(9606)Process
GO:0014003involved_in oligodendrocyte development1IMPHomo_sapiens(9606)Process
GO:0016020located_in membrane1IDAHomo_sapiens(9606)Component
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0043434involved_in response to peptide hormone1ISSHomo_sapiens(9606)Process
GO:0050852involved_in T cell receptor signaling pathway1IDAHomo_sapiens(9606)Process

Expression