Ensembl ID ENSG00000111361 Gene ID 1967 Accession 3257
Gene Symbol EIF2B1 Alias VWM1;EIF2B;EIF2BA;EIF2Balpha Full Name eukaryotic translation initiation factor 2B subunit alpha
Position 12 : 123620406 - 123633766 Length 13361 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Oct 2009]

ENSG00000111361 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000111361 EIF2B1 0.39 5.14e-38 KIRC
ENSG00000111361 EIF2B1 0.42 2.68e-15 LUSC
ENSG00000111361 EIF2B1 0.40 3.34e-12 KIRP
ENSG00000111361 EIF2B1 0.38 1.21e-12 LIHC
ENSG00000111361 EIF2B1 0.39 3.23e-13 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000111361 EIF2B1 SARC 0.02 high
ENSG00000111361 EIF2B1 LGG 0.00028 high
ENSG00000111361 EIF2B1 READ 0.0093 high
ENSG00000111361 EIF2B1 LUAD 0.012 high
ENSG00000111361 EIF2B1 BRCA 0.002 low
ENSG00000111361 EIF2B1 DLBC 0.038 low
ENSG00000111361 EIF2B1 PRAD 0.0034 high
ENSG00000111361 EIF2B1 TGCT 0.039 low
ENSG00000111361 EIF2B1 LAML 0.012 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000111361 EIF2B1 LUAD Del 0.714905 0.051405 0.279720 0.236434
ENSG00000111361 EIF2B1 UCS Del 0.770659 0.206863 0.491962 0.321429
ENSG00000111361 EIF2B1 PAAD Del 1.194446 0.055898 0.347525 0.217391
ENSG00000111361 EIF2B1 LIHC Del 2.789650 0.096268 0.444103 0.154054
ENSG00000111361 EIF2B1 BRCA Del 4.887810 0.092025 0.380378 0.196296
ENSG00000111361 EIF2B1 UCEC Del 2.175085 0.065080 0.403094 0.122449
ENSG00000111361 EIF2B1 OV Del 4.657486 0.242334 0.572097 0.329879