Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerCHIKVHIVSARS-COV-2
Drug Drug
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000109971 Gene ID 3312 Accession 5241
Symbol HSPA8 Alias LAP1;HSC54;HSC70;HSC71;HSP71;HSP73;LAP-1;NIP71;HEL-33;HSPA10;HEL-S-72p Full Name heat shock protein family A (Hsp70) member 8
Status Confidence Length 5742 bases Strand Minus strand
Position 11 : 123057489 - 123063230 RNA binding domain N.A.
Summary This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
34509361 Uncovering viral RNA-host cell interactions on a proteome-wide scale. Louisa Iselin 2022-01-01 Trends in biochemical sciences
34452292 Function of Host Protein Staufen1 in Rabies Virus Replication. Gaowen Liu 2021-07-22 Viruses
29867441 Cerebrospinal Fluid Concentration of Key Autophagy Protein Lamp2 Changes Little During Normal Aging. A David Loeffler 2018-01-01 Frontiers in aging neuroscience
35797800 Long noncoding RNA MAGI2-AS3 regulates the H2O2 level and cell senescence via HSPA8. Yingmin Zhang 2022-08-01 Redox biology
25299183 Antisense oligonucleotides capable of promoting specific target mRNA reduction via competing RNase H1-dependent and independent mechanisms. A Timothy Vickers 2014-01-01 PloS one
34769416 Establishment of Human-Induced Pluripotent Stem Cell-Derived Neurons-A Promising In Vitro Model for a Molecular Study of Rabies Virus and Host Interaction. Thanathom Chailangkarn 2021-11-05 International journal of molecular sciences
37372351 Association between HSPA8 Gene Variants and Ischemic Stroke: A Pilot Study Providing Additional Evidence for the Role of Heat Shock Proteins in Disease Pathogenesis. A Ksenia Kobzeva 2023-05-27 Genes
26641712 Recognition of distinct RNA motifs by the clustered CCCH zinc fingers of neuronal protein Unkempt. Jernej Murn 2016-01-01 Nature structural & molecular biology

Transcripts

Name Transcript ID bp Protein Translation ID
HSPA8-218 ENST00000532636 2306 646aa ENSP00000437125
HSPA8-221 ENST00000533540 1826 500aa ENSP00000437189
HSPA8-224 ENST00000534624 2264 646aa ENSP00000432083
HSPA8-202 ENST00000453788 2004 493aa ENSP00000404372
HSPA8-215 ENST00000532091 2301 No protein -
HSPA8-201 ENST00000227378 2186 646aa ENSP00000227378
HSPA8-222 ENST00000534319 1884 410aa ENSP00000433316
HSPA8-207 ENST00000526110 1924 627aa ENSP00000433584
HSPA8-203 ENST00000524552 963 223aa ENSP00000435908
HSPA8-208 ENST00000526686 740 150aa ENSP00000435019
HSPA8-220 ENST00000533238 465 No protein -
HSPA8-209 ENST00000526862 504 No protein -
HSPA8-211 ENST00000527983 1509 No protein -
HSPA8-212 ENST00000528292 1112 312aa ENSP00000432884
HSPA8-219 ENST00000532780 1194 No protein -
HSPA8-205 ENST00000525463 583 168aa ENSP00000436762
HSPA8-216 ENST00000532167 570 No protein -
HSPA8-206 ENST00000525624 1048 187aa ENSP00000435154
HSPA8-223 ENST00000534567 588 183aa ENSP00000431641
HSPA8-210 ENST00000527387 579 178aa ENSP00000436183
HSPA8-217 ENST00000532182 674 171aa ENSP00000434415
HSPA8-204 ENST00000524590 536 137aa ENSP00000434565
HSPA8-213 ENST00000530391 648 132aa ENSP00000434851
HSPA8-214 ENST00000531063 578 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
9733Echocardiography1.37074015971962E-517903301
9736Echocardiography8.19963834719263E-617903301
9795Echocardiography1.06965535430612E-517903301

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000109971homo_sapiensENSP0000032417378.899163.6086homo_sapiensENSP0000043208379.876264.3963
ENSG00000109971homo_sapiensENSP0000036762358.939136.5422homo_sapiensENSP0000043208346.439628.7926
ENSG00000109971homo_sapiensENSP0000028566756.475637.5796homo_sapiensENSP0000043208341.176527.3994
ENSG00000109971homo_sapiensENSP0000029718564.359449.19homo_sapiensENSP0000043208367.647151.7028
ENSG00000109971homo_sapiensENSP0000048015033.733719.3193homo_sapiensENSP0000043208352.167229.8762
ENSG00000109971homo_sapiensENSP0000036480592.667783.4633homo_sapiensENSP0000043208391.950582.8173
ENSG00000109971homo_sapiensENSP0000024720793.427286.698homo_sapiensENSP0000043208392.414985.7585
ENSG00000109971homo_sapiensENSP0000031021990.513278.3826homo_sapiensENSP0000043208390.092978.0186
ENSG00000109971homo_sapiensENSP0000030296142.857126.1905homo_sapiensENSP0000043208355.727634.0557
ENSG00000109971homo_sapiensENSP0000031868740.442924.359homo_sapiensENSP0000043208353.715232.3529
ENSG00000109971homo_sapiensENSP0000029646443.504225.3874homo_sapiensENSP0000043208356.501532.9721
ENSG00000109971homo_sapiensENSP0000036480192.823785.4914homo_sapiensENSP0000043208392.105384.8297
ENSG00000109971homo_sapiensENSP0000036480292.823785.4914homo_sapiensENSP0000043208392.105384.8297

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000109971homo_sapiensENSP00000432083100100pan_paniscusENSPPAP00000036545100100
ENSG00000109971homo_sapiensENSP00000432083100100pan_troglodytesENSPTRP00000074489100100
ENSG00000109971homo_sapiensENSP0000043208399.690499.5356ornithorhynchus_anatinusENSOANP0000002296699.690499.5356
ENSG00000109971homo_sapiensENSP0000043208399.535699.5356sarcophilus_harrisiiENSSHAP0000000865699.535699.5356
ENSG00000109971homo_sapiensENSP0000043208372.29172.1362choloepus_hoffmanniENSCHOP0000000321572.067971.9136
ENSG00000109971homo_sapiensENSP0000043208328.792625.387dasypus_novemcinctusENSDNOP0000002657475.303666.3968
ENSG00000109971homo_sapiensENSP0000043208395.510894.8916cercocebus_atysENSCATP0000001946699.355998.7118
ENSG00000109971homo_sapiensENSP00000432083100100macaca_mulattaENSMMUP00000055649100100
ENSG00000109971homo_sapiensENSP00000432083100100macaca_nemestrinaENSMNEP00000031510100100
ENSG00000109971homo_sapiensENSP0000043208398.916498.452mandrillus_leucophaeusENSMLEP0000001852598.916498.452
ENSG00000109971homo_sapiensENSP0000043208311.14559.59752vulpes_vulpesENSVVUP0000002185672.727362.6263
ENSG00000109971homo_sapiensENSP0000043208310.06198.82353vulpes_vulpesENSVVUP0000001300570.652261.9565
ENSG00000109971homo_sapiensENSP00000432083100100equus_asinusENSEASP0000504368598.62698.626
ENSG00000109971homo_sapiensENSP00000432083100100equus_caballusENSECAP0000001150086.711486.7114
ENSG00000109971homo_sapiensENSP0000043208310.68118.66873canis_lupus_familiarisENSCAFP0084502681261.607150
ENSG00000109971homo_sapiensENSP00000432083100100balaenoptera_musculusENSBMSP0001001397099.384699.3846
ENSG00000109971homo_sapiensENSP0000043208310099.8452felis_catusENSFCAP0000003795496.851696.7017
ENSG00000109971homo_sapiensENSP0000043208399.535699.5356monodelphis_domesticaENSMODP0000005487499.228499.2284
ENSG00000109971homo_sapiensENSP0000043208383.591380.9598monodon_monocerosENSMMNP0001501735495.238192.2399
ENSG00000109971homo_sapiensENSP0000043208399.690499.5356sus_scrofaENSSSCP0000003600292.929392.785
ENSG00000109971homo_sapiensENSP0000043208310099.8452jaculus_jaculusENSJJAP0000000885510099.8452
ENSG00000109971homo_sapiensENSP00000432083100100ovis_aries_rambouilletENSOARP0002002608398.027398.0273
ENSG00000109971homo_sapiensENSP00000432083100100ursus_maritimusENSUMAP00000031158100100
ENSG00000109971homo_sapiensENSP0000043208399.845299.8452delphinapterus_leucasENSDLEP0000002470499.230899.2308
ENSG00000109971homo_sapiensENSP0000043208310099.8452mus_musculusENSMUSP0000001580010099.8452
ENSG00000109971homo_sapiensENSP0000043208393.034192.4149aotus_nancymaaeENSANAP0000003868696.779496.1353
ENSG00000109971homo_sapiensENSP0000043208381.578981.5789tupaia_belangeriENSTBEP0000001002490.085590.0855
ENSG00000109971homo_sapiensENSP0000043208399.380899.0712mesocricetus_auratusENSMAUP0000001230199.380899.0712
ENSG00000109971homo_sapiensENSP0000043208310099.6904carlito_syrichtaENSTSYP0000003432410099.6904
ENSG00000109971homo_sapiensENSP0000043208387.151786.3777rattus_norvegicusENSRNOP0000009653599.119798.2394
ENSG00000109971homo_sapiensENSP0000043208310099.6904prolemur_simusENSPSMP0000000822799.384699.0769
ENSG00000109971homo_sapiensENSP0000043208387.461385.7585microtus_ochrogasterENSMOCP0000000637797.750995.8477
ENSG00000109971homo_sapiensENSP0000043208377.863877.709sorex_araneusENSSARP0000000014791.621191.439
ENSG00000109971homo_sapiensENSP0000043208310099.8452peromyscus_maniculatus_bairdiiENSPEMP0000002210810099.8452
ENSG00000109971homo_sapiensENSP0000043208310099.8452mus_spicilegusENSMSIP0000002172810099.8452
ENSG00000109971homo_sapiensENSP0000043208399.845299.8452myotis_lucifugusENSMLUP0000000440299.845299.8452
ENSG00000109971homo_sapiensENSP0000043208399.690499.5356rhinolophus_ferrumequinumENSRFEP0001000906299.690499.5356
ENSG00000109971homo_sapiensENSP0000043208386.068186.0681rhinolophus_ferrumequinumENSRFEP0001003038099.641699.6416
ENSG00000109971homo_sapiensENSP0000043208310099.8452neovison_visonENSNVIP0000000131110099.8452
ENSG00000109971homo_sapiensENSP00000432083100100canis_lupus_dingoENSCAFP00020014003100100
ENSG00000109971homo_sapiensENSP0000043208344.427243.0341phascolarctos_cinereusENSPCIP0000003036392.580689.6774
ENSG00000109971homo_sapiensENSP0000043208310099.8452nannospalax_galiliENSNGAP0000000880110099.8452
ENSG00000109971homo_sapiensENSP00000432083100100bos_grunniensENSBGRP0000002391296.417996.4179
ENSG00000109971homo_sapiensENSP00000432083100100cervus_hanglu_yarkandensisENSCHYP0000001684499.384699.3846
ENSG00000109971homo_sapiensENSP0000043208310099.8452catagonus_wagneriENSCWAP0000000202310099.8452
ENSG00000109971homo_sapiensENSP0000043208388.235388.2353mus_pahariMGP_PahariEiJ_P002308998.106798.1067
ENSG00000109971homo_sapiensENSP0000043208383.126970.5882caenorhabditis_elegansF44E5.5.183.255870.6977
ENSG00000109971homo_sapiensENSP0000043208383.126970.5882caenorhabditis_elegansF44E5.4.183.255870.6977
ENSG00000109971homo_sapiensENSP0000043208382.817368.5759caenorhabditis_elegansC12C8.1.183.203768.8958
ENSG00000109971homo_sapiensENSP0000043208347.832830.031caenorhabditis_elegansC30C11.4.139.819625
ENSG00000109971homo_sapiensENSP0000043208352.476829.257drosophila_melanogasterFBpp029299940.550222.6077
ENSG00000109971homo_sapiensENSP0000043208350.619230.805ciona_intestinalisENSCINP0000000165438.97523.7187
ENSG00000109971homo_sapiensENSP0000043208396.90491.6409eptatretus_burgeriENSEBUP0000001591696.159890.937
ENSG00000109971homo_sapiensENSP0000043208397.987693.6533callorhinchus_miliiENSCMIP0000001439693.088288.9706
ENSG00000109971homo_sapiensENSP0000043208398.761696.5944latimeria_chalumnaeENSLACP0000000131298.761696.5944
ENSG00000109971homo_sapiensENSP0000043208368.730764.0867lepisosteus_oculatusENSLOCP0000000489787.920881.9802
ENSG00000109971homo_sapiensENSP0000043208397.523294.2724clupea_harengusENSCHAP0000003349596.477893.2619
ENSG00000109971homo_sapiensENSP0000043208397.368493.8081clupea_harengusENSCHAP0000003345196.472492.9448
ENSG00000109971homo_sapiensENSP0000043208395.510891.1765clupea_harengusENSCHAP0000004241194.198589.9237
ENSG00000109971homo_sapiensENSP0000043208397.523293.3437danio_rerioENSDARP0000004374297.372593.1994
ENSG00000109971homo_sapiensENSP0000043208397.987695.2012danio_rerioENSDARP0000009076697.534794.7612
ENSG00000109971homo_sapiensENSP0000043208396.1390.4025danio_rerioENSDARP0000003932495.981590.2627
ENSG00000109971homo_sapiensENSP0000043208397.987693.6533carassius_auratusENSCARP0000007344597.987693.6533
ENSG00000109971homo_sapiensENSP0000043208398.297294.4272carassius_auratusENSCARP0000003263096.066692.2844
ENSG00000109971homo_sapiensENSP0000043208397.832893.9628carassius_auratusENSCARP0000007731796.636192.8135
ENSG00000109971homo_sapiensENSP0000043208395.975290.4025carassius_auratusENSCARP0000001013987.818782.7195
ENSG00000109971homo_sapiensENSP0000043208396.594492.1053astyanax_mexicanusENSAMXP000000313769691.5385
ENSG00000109971homo_sapiensENSP0000043208398.297294.4272astyanax_mexicanusENSAMXP0000000448597.692393.8462
ENSG00000109971homo_sapiensENSP0000043208397.987694.4272astyanax_mexicanusENSAMXP0000000309097.384693.8462
ENSG00000109971homo_sapiensENSP0000043208397.523294.1176ictalurus_punctatusENSIPUP0000002062596.923193.5385
ENSG00000109971homo_sapiensENSP0000043208314.396313.3127ictalurus_punctatusENSIPUP0000003600687.735881.1321
ENSG00000109971homo_sapiensENSP0000043208395.975290.5573ictalurus_punctatusENSIPUP0000000113295.384690
ENSG00000109971homo_sapiensENSP0000043208397.523292.5697esox_luciusENSELUP0000007806396.036691.1585
ENSG00000109971homo_sapiensENSP0000043208396.284889.7833esox_luciusENSELUP0000004070395.545389.0937
ENSG00000109971homo_sapiensENSP0000043208396.284892.7245esox_luciusENSELUP0000001637994.961891.4504
ENSG00000109971homo_sapiensENSP0000043208397.058890.8669electrophorus_electricusENSEEEP0000000832893.72287.7429
ENSG00000109971homo_sapiensENSP0000043208398.142494.1176electrophorus_electricusENSEEEP0000002167094.485890.611
ENSG00000109971homo_sapiensENSP0000043208314.396313.6223electrophorus_electricusENSEEEP0000002733983.783879.2793
ENSG00000109971homo_sapiensENSP0000043208339.318934.6749electrophorus_electricusENSEEEP0000000031280.126270.6625
ENSG00000109971homo_sapiensENSP0000043208397.058894.1176oncorhynchus_kisutchENSOKIP0000500280596.313493.3948
ENSG00000109971homo_sapiensENSP0000043208396.1391.3313oncorhynchus_kisutchENSOKIP0000503707693.383588.7218
ENSG00000109971homo_sapiensENSP0000043208395.510891.0217oncorhynchus_kisutchENSOKIP0000505651594.342589.9083
ENSG00000109971homo_sapiensENSP0000043208395.665689.4737oncorhynchus_kisutchENSOKIP0000503166190.350984.5029
ENSG00000109971homo_sapiensENSP0000043208395.201289.0093oncorhynchus_mykissENSOMYP0000005500995.054188.8717
ENSG00000109971homo_sapiensENSP0000043208396.594492.2601oncorhynchus_mykissENSOMYP0000006010196.445192.1175
ENSG00000109971homo_sapiensENSP0000043208397.058894.1176oncorhynchus_mykissENSOMYP0000009149995.144292.261
ENSG00000109971homo_sapiensENSP0000043208394.58290.0929oncorhynchus_mykissENSOMYP0000009576397.29392.6752
ENSG00000109971homo_sapiensENSP0000043208397.058894.1176salmo_salarENSSSAP0000005123393.442690.611
ENSG00000109971homo_sapiensENSP0000043208394.58289.7833salmo_salarENSSSAP0000008473693.140288.4146
ENSG00000109971homo_sapiensENSP0000043208391.331383.5913salmo_salarENSSSAP0000000449386.005878.7172
ENSG00000109971homo_sapiensENSP0000043208397.368492.5697salmo_salarENSSSAP0000010298387.726683.4031
ENSG00000109971homo_sapiensENSP0000043208310.06199.28793salmo_truttaENSSTUP0000000848280.246974.0741
ENSG00000109971homo_sapiensENSP0000043208397.213693.8081gadus_morhuaENSGMOP0000004396089.714386.5714
ENSG00000109971homo_sapiensENSP0000043208397.058891.4861fundulus_heteroclitusENSFHEP0000000423196.610291.0632
ENSG00000109971homo_sapiensENSP0000043208397.213693.8081fundulus_heteroclitusENSFHEP0000000957597.213693.8081
ENSG00000109971homo_sapiensENSP0000043208395.975290.0929fundulus_heteroclitusENSFHEP0000001842195.531689.6764
ENSG00000109971homo_sapiensENSP0000043208395.975290.4025poecilia_reticulataENSPREP0000000547195.531689.9846
ENSG00000109971homo_sapiensENSP0000043208396.90493.6533poecilia_reticulataENSPREP0000002046796.90493.6533
ENSG00000109971homo_sapiensENSP0000043208395.201289.4737poecilia_reticulataENSPREP0000001692596.546390.7378
ENSG00000109971homo_sapiensENSP0000043208396.1390.5573xiphophorus_maculatusENSXMAP0000001060196.279190.6977
ENSG00000109971homo_sapiensENSP0000043208394.891688.5449xiphophorus_maculatusENSXMAP0000000173096.232389.7959
ENSG00000109971homo_sapiensENSP0000043208397.213693.9628xiphophorus_maculatusENSXMAP0000000160997.213693.9628
ENSG00000109971homo_sapiensENSP0000043208394.58288.8545oryzias_latipesENSORLP0000000802491.19485.6716
ENSG00000109971homo_sapiensENSP0000043208397.523294.4272oryzias_latipesENSORLP000000361219087.1429
ENSG00000109971homo_sapiensENSP0000043208397.368492.2601oryzias_latipesENSORLP0000002702497.217992.1175
ENSG00000109971homo_sapiensENSP0000043208397.058893.3437cyclopterus_lumpusENSCLMP0000502751493.442689.8659
ENSG00000109971homo_sapiensENSP0000043208393.653387.7709cyclopterus_lumpusENSCLMP0000502432090.568984.8802
ENSG00000109971homo_sapiensENSP0000043208397.058891.7957cyclopterus_lumpusENSCLMP0000500988693.303688.244
ENSG00000109971homo_sapiensENSP0000043208395.665690.4025oreochromis_niloticusENSONIP0000000342795.81490.5426
ENSG00000109971homo_sapiensENSP0000043208392.724588.6997oreochromis_niloticusENSONIP0000007618490.210886.2952
ENSG00000109971homo_sapiensENSP0000043208397.987693.1889oreochromis_niloticusENSONIP0000007700197.685292.9012
ENSG00000109971homo_sapiensENSP0000043208397.523294.2724haplochromis_burtoniENSHBUP0000001929496.923193.6923
ENSG00000109971homo_sapiensENSP0000043208395.820490.0929haplochromis_burtoniENSHBUP0000002983996.567990.7956
ENSG00000109971homo_sapiensENSP0000043208397.523292.7245haplochromis_burtoniENSHBUP0000000255397.222292.4383
ENSG00000109971homo_sapiensENSP000004320838.668737.27554haplochromis_burtoniENSHBUP0000001935850.450542.3423
ENSG00000109971homo_sapiensENSP0000043208396.1390.2477astatotilapia_callipteraENSACLP0000000034095.685789.8305
ENSG00000109971homo_sapiensENSP0000043208397.523294.2724astatotilapia_callipteraENSACLP0000000628696.923193.6923
ENSG00000109971homo_sapiensENSP0000043208373.684269.8142astatotilapia_callipteraENSACLP0000001371097.341592.229
ENSG00000109971homo_sapiensENSP0000043208311.60999.59752astatotilapia_callipteraENSACLP0000000637155.147145.5882
ENSG00000109971homo_sapiensENSP0000043208398.142493.0341sparus_aurataENSSAUP0001004628196.941991.896
ENSG00000109971homo_sapiensENSP0000043208396.439690.5573sparus_aurataENSSAUP0001005160592.023686.4106
ENSG00000109971homo_sapiensENSP0000043208396.439692.5697sparus_aurataENSSAUP0001001031293.684289.9248
ENSG00000109971homo_sapiensENSP0000043208395.820490.7121lates_calcariferENSLCAP0001001698493.787988.7879
ENSG00000109971homo_sapiensENSP0000043208398.142493.4985lates_calcariferENSLCAP0001005189797.239392.638
ENSG00000109971homo_sapiensENSP0000043208397.368493.9628lates_calcariferENSLCAP0001002854096.769293.3846
ENSG00000109971homo_sapiensENSP0000043208398.297296.2848xenopus_tropicalisENSXETP0000008701196.358194.3854
ENSG00000109971homo_sapiensENSP0000043208399.690499.226chrysemys_picta_belliiENSCPBP0000002084898.470998.0122
ENSG00000109971homo_sapiensENSP0000043208399.22698.452sphenodon_punctatusENSSPUP0000001526499.22698.452
ENSG00000109971homo_sapiensENSP0000043208399.690499.226crocodylus_porosusENSCPRP0000500383699.690499.226
ENSG00000109971homo_sapiensENSP0000043208399.22698.6068laticauda_laticaudataENSLLTP0000002070199.22698.6068
ENSG00000109971homo_sapiensENSP0000043208392.879390.7121notechis_scutatusENSNSUP0000001786795.087292.8685
ENSG00000109971homo_sapiensENSP0000043208399.22698.6068pseudonaja_textilisENSPTXP0000001768099.22698.6068
ENSG00000109971homo_sapiensENSP0000043208394.736894.2724anas_platyrhynchos_platyrhynchosENSAPLP0000002721188.567388.1331
ENSG00000109971homo_sapiensENSP0000043208393.808192.1053gallus_gallusENSGALP0001003861385.957484.3972
ENSG00000109971homo_sapiensENSP0000043208399.845299.3808meleagris_gallopavoENSMGAP0000000145099.845299.3808
ENSG00000109971homo_sapiensENSP0000043208399.845299.226serinus_canariaENSSCAP0000001354099.845299.226
ENSG00000109971homo_sapiensENSP0000043208393.343791.4861parus_majorENSPMJP0000001110491.363689.5455
ENSG00000109971homo_sapiensENSP0000043208399.845298.7616anolis_carolinensisENSACAP0000000479899.845298.7616
ENSG00000109971homo_sapiensENSP0000043208397.523294.2724neolamprologus_brichardiENSNBRP0000000630896.923193.6923
ENSG00000109971homo_sapiensENSP0000043208398.297293.4985neolamprologus_brichardiENSNBRP0000002935698.297293.4985
ENSG00000109971homo_sapiensENSP0000043208395.975290.2477neolamprologus_brichardiENSNBRP0000000875796.12490.3876
ENSG00000109971homo_sapiensENSP0000043208399.380898.6068naja_najaENSNNAP0000001680199.380898.6068
ENSG00000109971homo_sapiensENSP0000043208399.845298.9164podarcis_muralisENSPMRP0000003319199.845298.9164
ENSG00000109971homo_sapiensENSP0000043208399.845299.226geospiza_fortisENSGFOP0000002067199.845299.226
ENSG00000109971homo_sapiensENSP0000043208399.845299.226taeniopygia_guttataENSTGUP0000000050399.845299.226
ENSG00000109971homo_sapiensENSP0000043208394.427291.4861erpetoichthys_calabaricusENSECRP0000002985493.558390.6442
ENSG00000109971homo_sapiensENSP0000043208398.606895.8204erpetoichthys_calabaricusENSECRP0000002952691.391788.8092
ENSG00000109971homo_sapiensENSP0000043208397.213692.2601kryptolebias_marmoratusENSKMAP0000001898196.615491.6923
ENSG00000109971homo_sapiensENSP0000043208395.665689.4737kryptolebias_marmoratusENSKMAP0000002410894.495488.3792
ENSG00000109971homo_sapiensENSP0000043208396.594493.3437kryptolebias_marmoratusENSKMAP0000002176096.296393.0556
ENSG00000109971homo_sapiensENSP0000043208399.845299.226salvator_merianaeENSSMRP0000002855499.845299.226
ENSG00000109971homo_sapiensENSP0000043208343.188937.9257oryzias_javanicusENSOJAP0000000123285.321174.9235
ENSG00000109971homo_sapiensENSP0000043208397.523294.4272amphilophus_citrinellusENSACIP0000002475696.923193.8462
ENSG00000109971homo_sapiensENSP0000043208395.975290.5573amphilophus_citrinellusENSACIP0000000646196.12490.6977
ENSG00000109971homo_sapiensENSP0000043208398.606893.6533amphilophus_citrinellusENSACIP0000000946398.606893.6533
ENSG00000109971homo_sapiensENSP0000043208315.479911.6099dicentrarchus_labraxENSDLAP0000500310683.333362.5
ENSG00000109971homo_sapiensENSP0000043208398.142493.0341dicentrarchus_labraxENSDLAP0000503603197.538592.4615
ENSG00000109971homo_sapiensENSP0000043208396.1390.4025dicentrarchus_labraxENSDLAP0000502838790.130684.7605
ENSG00000109971homo_sapiensENSP0000043208394.736890.2477dicentrarchus_labraxENSDLAP0000507320990.132585.8616
ENSG00000109971homo_sapiensENSP0000043208398.142493.1889amphiprion_perculaENSAPEP0000000992198.142493.1889
ENSG00000109971homo_sapiensENSP0000043208387.306583.7461amphiprion_perculaENSAPEP0000001985188.818985.1969
ENSG00000109971homo_sapiensENSP0000043208396.1390.7121amphiprion_perculaENSAPEP0000002111096.879991.4197
ENSG00000109971homo_sapiensENSP0000043208397.523294.4272oryzias_sinensisENSOSIP0000002889091.172288.2779
ENSG00000109971homo_sapiensENSP0000043208395.665690.2477oryzias_sinensisENSOSIP0000001874872.535268.4272
ENSG00000109971homo_sapiensENSP0000043208396.1390.7121oryzias_sinensisENSOSIP0000000695991.45886.3034
ENSG00000109971homo_sapiensENSP0000043208399.535699.0712pelodiscus_sinensisENSPSIP0000001398599.381898.9181
ENSG00000109971homo_sapiensENSP0000043208399.690499.0712gopherus_evgoodeiENSGEVP0000502419499.690499.0712
ENSG00000109971homo_sapiensENSP0000043208399.535699.0712chelonoidis_abingdoniiENSCABP0000000594898.619698.1595
ENSG00000109971homo_sapiensENSP0000043208395.820490.8669seriola_dumeriliENSSDUP0000001654195.084590.169
ENSG00000109971homo_sapiensENSP0000043208397.832893.4985seriola_dumeriliENSSDUP0000000434597.081492.7803
ENSG00000109971homo_sapiensENSP0000043208395.665692.4149seriola_dumeriliENSSDUP0000002940596.865293.5737
ENSG00000109971homo_sapiensENSP0000043208395.510890.2477cottoperca_gobioENSCGOP0000003337193.484888.3333
ENSG00000109971homo_sapiensENSP0000043208397.368491.6409cottoperca_gobioENSCGOP0000004082491.959186.5497
ENSG00000109971homo_sapiensENSP0000043208394.58290.5573cottoperca_gobioENSCGOP0000005068991.879787.9699
ENSG00000109971homo_sapiensENSP0000043208399.845299.3808struthio_camelus_australisENSSCUP0000001563099.845299.3808
ENSG00000109971homo_sapiensENSP0000043208394.891694.582anser_brachyrhynchusENSABRP0000000602299.837199.5114
ENSG00000109971homo_sapiensENSP0000043208397.213691.7957gasterosteus_aculeatusENSGACP0000001393096.024590.6728
ENSG00000109971homo_sapiensENSP0000043208396.1389.9381gasterosteus_aculeatusENSGACP0000001005696.428690.2174
ENSG00000109971homo_sapiensENSP0000043208397.213693.8081gasterosteus_aculeatusENSGACP0000002657996.913693.5185
ENSG00000109971homo_sapiensENSP0000043208396.439689.7833cynoglossus_semilaevisENSCSEP0000000871196.589189.9225
ENSG00000109971homo_sapiensENSP0000043208396.749293.0341cynoglossus_semilaevisENSCSEP0000003061196.30292.604
ENSG00000109971homo_sapiensENSP0000043208397.058893.6533poecilia_formosaENSPFOP0000000957397.058893.6533
ENSG00000109971homo_sapiensENSP0000043208395.975290.2477poecilia_formosaENSPFOP0000000705995.531689.8305
ENSG00000109971homo_sapiensENSP0000043208395.046489.1641poecilia_formosaENSPFOP0000000826196.389390.4239
ENSG00000109971homo_sapiensENSP0000043208396.284890.0929myripristis_murdjanENSMMDP0000503494394.672888.5845
ENSG00000109971homo_sapiensENSP0000043208392.105387.3065myripristis_murdjanENSMMDP0000503435290.978686.2385
ENSG00000109971homo_sapiensENSP0000043208398.45294.2724myripristis_murdjanENSMMDP0000501228298.604794.4186
ENSG00000109971homo_sapiensENSP0000043208398.142493.1889sander_luciopercaENSSLUP0000005384794.205189.4502
ENSG00000109971homo_sapiensENSP0000043208397.368493.4985sander_luciopercaENSSLUP0000002237194.444490.6907
ENSG00000109971homo_sapiensENSP0000043208396.284890.5573sander_luciopercaENSSLUP0000004311493.533887.9699
ENSG00000109971homo_sapiensENSP0000043208399.845299.3808strigops_habroptilaENSSHBP0000501937199.845299.3808
ENSG00000109971homo_sapiensENSP0000043208398.142493.1889amphiprion_ocellarisENSAOCP0000001517798.142493.1889
ENSG00000109971homo_sapiensENSP0000043208392.569788.5449amphiprion_ocellarisENSAOCP0000002622785.919582.1839
ENSG00000109971homo_sapiensENSP0000043208395.975290.7121amphiprion_ocellarisENSAOCP0000002148495.531690.2928
ENSG00000109971homo_sapiensENSP0000043208399.690499.226terrapene_carolina_triunguisENSTMTP0000000801099.690499.226
ENSG00000109971homo_sapiensENSP000004320839.907129.59752hucho_huchoENSHHUP0000003995088.888986.1111
ENSG00000109971homo_sapiensENSP0000043208332.198131.1146hucho_huchoENSHHUP0000002396399.047695.7143
ENSG00000109971homo_sapiensENSP0000043208329.411828.483hucho_huchoENSHHUP0000008833593.596190.6404
ENSG00000109971homo_sapiensENSP0000043208397.213694.1176betta_splendensENSBSLP0000000832889.07886.2411
ENSG00000109971homo_sapiensENSP0000043208398.297293.4985betta_splendensENSBSLP0000004175393.934989.3491
ENSG00000109971homo_sapiensENSP0000043208395.975291.3313betta_splendensENSBSLP0000003197992.953588.4558
ENSG00000109971homo_sapiensENSP0000043208397.832893.4985pygocentrus_nattereriENSPNAP0000000682197.380693.0663
ENSG00000109971homo_sapiensENSP0000043208397.523294.582pygocentrus_nattereriENSPNAP0000003178397.072494.1448
ENSG00000109971homo_sapiensENSP0000043208323.219820.4334pygocentrus_nattereriENSPNAP0000001350090.361479.5181
ENSG00000109971homo_sapiensENSP0000043208396.439691.4861pygocentrus_nattereriENSPNAP0000000915896.439691.4861
ENSG00000109971homo_sapiensENSP0000043208398.45293.6533anabas_testudineusENSATEP0000003802996.803692.0852
ENSG00000109971homo_sapiensENSP0000043208397.368494.1176anabas_testudineusENSATEP0000003693996.030592.8244
ENSG00000109971homo_sapiensENSP0000043208316.253912.8483anabas_testudineusENSATEP0000002560587.569.1667
ENSG00000109971homo_sapiensENSP0000043208396.1390.8669anabas_testudineusENSATEP0000001392795.685790.4468
ENSG00000109971homo_sapiensENSP0000043208349.535630.4954ciona_savignyiENSCSAVP0000001760635.914722.11
ENSG00000109971homo_sapiensENSP0000043208342.724524.613saccharomyces_cerevisiaeYPL106C39.826822.9437
ENSG00000109971homo_sapiensENSP0000043208343.962825.387saccharomyces_cerevisiaeYBR169C40.981223.6652
ENSG00000109971homo_sapiensENSP0000043208397.67893.4985seriola_lalandi_dorsalisENSSLDP0000001816396.927892.7803
ENSG00000109971homo_sapiensENSP0000043208317.801915.4799seriola_lalandi_dorsalisENSSLDP0000001491287.121275.7576
ENSG00000109971homo_sapiensENSP0000043208397.213693.6533seriola_lalandi_dorsalisENSSLDP0000001576196.31992.7914
ENSG00000109971homo_sapiensENSP0000043208318.730616.8731seriola_lalandi_dorsalisENSSLDP0000001296690.977481.9549
ENSG00000109971homo_sapiensENSP0000043208395.820490.7121seriola_lalandi_dorsalisENSSLDP0000001923895.377590.2928
ENSG00000109971homo_sapiensENSP0000043208312.383911.9195seriola_lalandi_dorsalisENSSLDP0000000872896.385592.7711
ENSG00000109971homo_sapiensENSP0000043208392.879387.3065labrus_bergyltaENSLBEP0000001335895.541489.8089
ENSG00000109971homo_sapiensENSP0000043208391.950586.2229labrus_bergyltaENSLBEP0000003095593.103487.3041
ENSG00000109971homo_sapiensENSP0000043208397.523294.1176labrus_bergyltaENSLBEP0000002736596.774293.3948
ENSG00000109971homo_sapiensENSP0000043208397.523294.2724pundamilia_nyerereiENSPNYP0000000236896.923193.6923
ENSG00000109971homo_sapiensENSP0000043208397.987693.0341pundamilia_nyerereiENSPNYP0000001971897.987693.0341
ENSG00000109971homo_sapiensENSP0000043208395.820490.0929pundamilia_nyerereiENSPNYP0000001111995.377589.6764
ENSG00000109971homo_sapiensENSP0000043208397.368494.1176mastacembelus_armatusENSMAMP0000005503195.738292.5419
ENSG00000109971homo_sapiensENSP0000043208397.987693.0341mastacembelus_armatusENSMAMP0000002509497.685292.7469
ENSG00000109971homo_sapiensENSP0000043208396.284890.0929mastacembelus_armatusENSMAMP0000002382196.284890.0929
ENSG00000109971homo_sapiensENSP0000043208397.213691.6409stegastes_partitusENSSPAP0000001941697.213691.6409
ENSG00000109971homo_sapiensENSP0000043208396.1390.4025stegastes_partitusENSSPAP0000001928995.245489.5705
ENSG00000109971homo_sapiensENSP0000043208397.368493.9628stegastes_partitusENSSPAP0000000080296.769293.3846
ENSG00000109971homo_sapiensENSP0000043208312.22918.97833stegastes_partitusENSSPAP0000001328576.69956.3107
ENSG00000109971homo_sapiensENSP0000043208395.665689.4737oncorhynchus_tshawytschaENSOTSP0000507563489.825684.0116
ENSG00000109971homo_sapiensENSP0000043208396.90493.8081oncorhynchus_tshawytschaENSOTSP0000508051893.853190.8546
ENSG00000109971homo_sapiensENSP0000043208392.724588.0805oncorhynchus_tshawytschaENSOTSP0000502617293.157188.4914
ENSG00000109971homo_sapiensENSP0000043208396.90493.8081oncorhynchus_tshawytschaENSOTSP0000504543293.853190.8546
ENSG00000109971homo_sapiensENSP0000043208397.058892.5697oncorhynchus_tshawytschaENSOTSP000050932409590.6061
ENSG00000109971homo_sapiensENSP0000043208395.665689.4737oncorhynchus_tshawytschaENSOTSP0000509220989.825684.0116
ENSG00000109971homo_sapiensENSP0000043208349.22646.7492acanthochromis_polyacanthusENSAPOP0000002240474.125970.3963
ENSG00000109971homo_sapiensENSP0000043208398.297293.1889acanthochromis_polyacanthusENSAPOP0000000201398.297293.1889
ENSG00000109971homo_sapiensENSP0000043208395.820490.4025acanthochromis_polyacanthusENSAPOP0000001762695.377589.9846
ENSG00000109971homo_sapiensENSP0000043208344.272439.4737acanthochromis_polyacanthusENSAPOP0000000224582.898673.913
ENSG00000109971homo_sapiensENSP0000043208318.421116.5635acanthochromis_polyacanthusENSAPOP0000002242292.248182.9457
ENSG00000109971homo_sapiensENSP0000043208399.845299.3808aquila_chrysaetos_chrysaetosENSACCP0002001068499.845299.3808
ENSG00000109971homo_sapiensENSP0000043208396.90493.3437nothobranchius_furzeriENSNFUP0001502809696.159892.6267
ENSG00000109971homo_sapiensENSP0000043208396.284889.7833nothobranchius_furzeriENSNFUP0001500670992.011885.7988
ENSG00000109971homo_sapiensENSP0000043208395.201289.4737nothobranchius_furzeriENSNFUP0001503989292.203986.6567
ENSG00000109971homo_sapiensENSP0000043208397.67894.1176cyprinodon_variegatusENSCVAP0000000044697.67894.1176
ENSG00000109971homo_sapiensENSP0000043208395.975290.4025cyprinodon_variegatusENSCVAP0000000847396.12490.5426
ENSG00000109971homo_sapiensENSP0000043208397.67892.7245cyprinodon_variegatusENSCVAP0000000637597.52792.5811
ENSG00000109971homo_sapiensENSP0000043208397.67893.9628denticeps_clupeoidesENSDCDP0000002608294.179190.597
ENSG00000109971homo_sapiensENSP0000043208397.987693.6533denticeps_clupeoidesENSDCDP0000002476496.641292.3664
ENSG00000109971homo_sapiensENSP0000043208395.35690.0929denticeps_clupeoidesENSDCDP0000005081989.534984.593
ENSG00000109971homo_sapiensENSP0000043208397.987692.7245larimichthys_croceaENSLCRP0000504054994.336889.2697
ENSG00000109971homo_sapiensENSP0000043208317.956717.4923larimichthys_croceaENSLCRP0000500383892.890.4
ENSG00000109971homo_sapiensENSP0000043208397.368493.6533larimichthys_croceaENSLCRP0000506120495.015191.3897
ENSG00000109971homo_sapiensENSP0000043208393.962888.0805larimichthys_croceaENSLCRP0000502475192.530586.7378
ENSG00000109971homo_sapiensENSP0000043208397.832894.1176takifugu_rubripesENSTRUP0000006528897.230893.5385
ENSG00000109971homo_sapiensENSP0000043208393.962889.0093takifugu_rubripesENSTRUP0000005622491.004586.2069
ENSG00000109971homo_sapiensENSP0000043208399.845299.226ficedula_albicollisENSFALP0000000606799.845299.226
ENSG00000109971homo_sapiensENSP0000043208321.207419.5046hippocampus_comesENSHCOP0000001592195.804288.1119
ENSG00000109971homo_sapiensENSP0000043208397.67893.8081hippocampus_comesENSHCOP0000000562697.076993.2308
ENSG00000109971homo_sapiensENSP0000043208317.647114.3963hippocampus_comesENSHCOP0000000550587.022970.9924
ENSG00000109971homo_sapiensENSP0000043208398.142493.9628cyprinus_carpio_carpioENSCCRP0000012086798.142493.9628
ENSG00000109971homo_sapiensENSP0000043208396.1390.4025cyprinus_carpio_carpioENSCCRP0000011835894.809289.1603
ENSG00000109971homo_sapiensENSP0000043208398.142494.4272cyprinus_carpio_carpioENSCCRP0000016284895.052591.4543
ENSG00000109971homo_sapiensENSP0000043208396.749293.8081cyprinus_carpio_carpioENSCCRP0000000241696.153893.2308
ENSG00000109971homo_sapiensENSP0000043208394.117691.0217cyprinus_carpio_carpioENSCCRP0000014479392.824489.771
ENSG00000109971homo_sapiensENSP0000043208399.845299.3808coturnix_japonicaENSCJPP0000500967599.845299.3808
ENSG00000109971homo_sapiensENSP0000043208395.975290.4025poecilia_latipinnaENSPLAP0000000273295.531689.9846
ENSG00000109971homo_sapiensENSP0000043208397.058893.6533poecilia_latipinnaENSPLAP0000002639197.058893.6533
ENSG00000109971homo_sapiensENSP0000043208395.046489.1641poecilia_latipinnaENSPLAP0000001276796.389390.4239
ENSG00000109971homo_sapiensENSP0000043208388.390185.2941sinocyclocheilus_grahamiENSSGRP0000002656795.166791.8333
ENSG00000109971homo_sapiensENSP0000043208389.783383.5913sinocyclocheilus_grahamiENSSGRP0000000191791.482785.1735
ENSG00000109971homo_sapiensENSP0000043208388.080583.2817sinocyclocheilus_grahamiENSSGRP0000000688991.0486.08
ENSG00000109971homo_sapiensENSP0000043208397.67893.8081sinocyclocheilus_grahamiENSSGRP0000008729791.58287.9536
ENSG00000109971homo_sapiensENSP0000043208397.987695.0464sinocyclocheilus_grahamiENSSGRP0000005320594.760591.9162
ENSG00000109971homo_sapiensENSP0000043208317.337514.3963sinocyclocheilus_grahamiENSSGRP0000002672889.674.4
ENSG00000109971homo_sapiensENSP0000043208337.616134.2105maylandia_zebraENSMZEP0000501644383.793176.2069
ENSG00000109971homo_sapiensENSP0000043208395.820490.0929maylandia_zebraENSMZEP0000503458895.377589.6764
ENSG00000109971homo_sapiensENSP0000043208397.987693.1889maylandia_zebraENSMZEP0000500653197.987693.1889
ENSG00000109971homo_sapiensENSP0000043208397.523294.2724maylandia_zebraENSMZEP0000503173796.923193.6923
ENSG00000109971homo_sapiensENSP0000043208314.705911.9195maylandia_zebraENSMZEP0000501643584.070868.1416
ENSG00000109971homo_sapiensENSP0000043208395.820491.0217tetraodon_nigroviridisENSTNIP0000002164795.230890.4615
ENSG00000109971homo_sapiensENSP0000043208397.67893.8081tetraodon_nigroviridisENSTNIP0000001144397.076993.2308
ENSG00000109971homo_sapiensENSP0000043208391.331385.6037paramormyrops_kingsleyaeENSPKIP0000003546988.721883.1579
ENSG00000109971homo_sapiensENSP0000043208391.795786.5325paramormyrops_kingsleyaeENSPKIP0000001894681.010976.3661
ENSG00000109971homo_sapiensENSP0000043208396.749291.6409scleropages_formosusENSSFOP0001505986892.319187.4446
ENSG00000109971homo_sapiensENSP0000043208398.45294.7368scleropages_formosusENSSFOP0001507121896.803693.1507
ENSG00000109971homo_sapiensENSP0000043208393.034191.3313leptobrachium_leishanenseENSLLEP0000003819696.623894.8553
ENSG00000109971homo_sapiensENSP0000043208396.749294.582leptobrachium_leishanenseENSLLEP0000003481996.450694.2901
ENSG00000109971homo_sapiensENSP0000043208388.854587.4613leptobrachium_leishanenseENSLLEP0000001159996.147494.6399
ENSG00000109971homo_sapiensENSP0000043208397.213695.6656leptobrachium_leishanenseENSLLEP0000004000196.913695.3704
ENSG00000109971homo_sapiensENSP0000043208364.241562.5387leptobrachium_leishanenseENSLLEP0000003836893.258490.7865
ENSG00000109971homo_sapiensENSP0000043208391.176589.6285leptobrachium_leishanenseENSLLEP0000000202197.516695.8609
ENSG00000109971homo_sapiensENSP0000043208396.749292.5697scophthalmus_maximusENSSMAP0000006638595.712191.5773
ENSG00000109971homo_sapiensENSP0000043208392.260186.3777scophthalmus_maximusENSSMAP0000006256293.710787.7358
ENSG00000109971homo_sapiensENSP0000043208396.439691.3313scophthalmus_maximusENSSMAP0000006205190.420985.6313
ENSG00000109971homo_sapiensENSP0000043208397.523294.2724oryzias_melastigmaENSOMEP0000000968996.923193.6923
ENSG00000109971homo_sapiensENSP0000043208395.975290.7121oryzias_melastigmaENSOMEP0000001688096.42391.1353
ENSG00000109971homo_sapiensENSP0000043208396.284891.4861oryzias_melastigmaENSOMEP0000002504795.987791.2037

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000398involved_in mRNA splicing, via spliceosome1NASHomo_sapiens(9606)Process
GO:0000974part_of Prp19 complex2IDA,IPIHomo_sapiens(9606)Component
GO:0001664enables G protein-coupled receptor binding1IPIHomo_sapiens(9606)Function
GO:0001786enables phosphatidylserine binding1IEAHomo_sapiens(9606)Function
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IDAHomo_sapiens(9606)Function
GO:0005576located_in extracellular region1TASHomo_sapiens(9606)Component
GO:0005615located_in extracellular space1HDAHomo_sapiens(9606)Component
GO:0005634is_active_in nucleus2IBA,IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1TASHomo_sapiens(9606)Component
GO:0005681part_of spliceosomal complex1IPIHomo_sapiens(9606)Component
GO:0005730located_in nucleolus1IEAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm1IBAHomo_sapiens(9606)Component
GO:0005764is_active_in lysosome1IBAHomo_sapiens(9606)Component
GO:0005765is_active_in lysosomal membrane2IDA,ISSHomo_sapiens(9606)Component
GO:0005770located_in late endosome1IEAHomo_sapiens(9606)Component
GO:0005776is_active_in autophagosome1IBAHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0005886is_active_in plasma membrane2IBA,TASHomo_sapiens(9606)Component
GO:0005925located_in focal adhesion1HDAHomo_sapiens(9606)Component
GO:0006457involved_in protein folding1NASHomo_sapiens(9606)Process
GO:0006986involved_in response to unfolded protein1NASHomo_sapiens(9606)Process
GO:0009267involved_in cellular response to starvation1TASHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0016887enables ATP hydrolysis activity3IBA,NAS,TASHomo_sapiens(9606)Function
GO:0019899enables enzyme binding1IPIHomo_sapiens(9606)Function
GO:0023026enables MHC class II protein complex binding1HDAHomo_sapiens(9606)Function
GO:0030425is_active_in dendrite1IBAHomo_sapiens(9606)Component
GO:0030674enables protein-macromolecule adaptor activity2IDA,IPIHomo_sapiens(9606)Function
GO:0031072enables heat shock protein binding2IBA,IPIHomo_sapiens(9606)Function
GO:0031625enables ubiquitin protein ligase binding1IPIHomo_sapiens(9606)Function
GO:0031647involved_in regulation of protein stability1IMPHomo_sapiens(9606)Process
GO:0034774located_in secretory granule lumen1TASHomo_sapiens(9606)Component
GO:0042026involved_in protein refolding2IBA,IDAHomo_sapiens(9606)Process
GO:0042470located_in melanosome1IEAHomo_sapiens(9606)Component
GO:0043195is_active_in terminal bouton1IBAHomo_sapiens(9606)Component
GO:0043202located_in lysosomal lumen1TASHomo_sapiens(9606)Component
GO:0043254involved_in regulation of protein-containing complex assembly1TASHomo_sapiens(9606)Process
GO:0044183enables protein folding chaperone1IBAHomo_sapiens(9606)Function
GO:0044829involved_in positive regulation by host of viral genome replication1IEAHomo_sapiens(9606)Process
GO:0045296enables cadherin binding1HDAHomo_sapiens(9606)Function
GO:0045892involved_in negative regulation of DNA-templated transcription1IDAHomo_sapiens(9606)Process
GO:0046034involved_in ATP metabolic process1IDAHomo_sapiens(9606)Process
GO:0048026involved_in positive regulation of mRNA splicing, via spliceosome1IEAHomo_sapiens(9606)Process
GO:0048471located_in perinuclear region of cytoplasm1IEAHomo_sapiens(9606)Component
GO:0051082enables unfolded protein binding1IDAHomo_sapiens(9606)Function
GO:0051085involved_in chaperone cofactor-dependent protein refolding1IBAHomo_sapiens(9606)Process
GO:0051087enables protein-folding chaperone binding1IPIHomo_sapiens(9606)Function
GO:0051726involved_in regulation of cell cycle1IEAHomo_sapiens(9606)Process
GO:0055131enables C3HC4-type RING finger domain binding1IPIHomo_sapiens(9606)Function
GO:0061024involved_in membrane organization1TASHomo_sapiens(9606)Process
GO:0061202located_in clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane1TASHomo_sapiens(9606)Component
GO:0061635involved_in regulation of protein complex stability1ISSHomo_sapiens(9606)Process
GO:0061684involved_in chaperone-mediated autophagy2ISS,TASHomo_sapiens(9606)Process
GO:0061738involved_in late endosomal microautophagy1IBAHomo_sapiens(9606)Process
GO:0061740involved_in protein targeting to lysosome involved in chaperone-mediated autophagy4IBA,IDA,IMP,TASHomo_sapiens(9606)Process
GO:0070062located_in extracellular exosome2HDA,IDAHomo_sapiens(9606)Component
GO:0071383involved_in cellular response to steroid hormone stimulus1TASHomo_sapiens(9606)Process
GO:0072318involved_in clathrin coat disassembly1IBAHomo_sapiens(9606)Process
GO:0072562located_in blood microparticle1HDAHomo_sapiens(9606)Component
GO:0098575located_in lumenal side of lysosomal membrane1TASHomo_sapiens(9606)Component
GO:0098684located_in photoreceptor ribbon synapse1IEAHomo_sapiens(9606)Component
GO:0098690located_in glycinergic synapse1IEAHomo_sapiens(9606)Component
GO:0098978located_in glutamatergic synapse1IEAHomo_sapiens(9606)Component
GO:0099175involved_in regulation of postsynapse organization1IEAHomo_sapiens(9606)Process
GO:0099523is_active_in presynaptic cytosol1IBAHomo_sapiens(9606)Component
GO:0099524is_active_in postsynaptic cytosol1IBAHomo_sapiens(9606)Component
GO:0099634located_in postsynaptic specialization membrane1IEAHomo_sapiens(9606)Component
GO:0101031part_of protein folding chaperone complex1IPIHomo_sapiens(9606)Component
GO:0140545enables ATP-dependent protein disaggregase activity1IDAHomo_sapiens(9606)Function
GO:0140597enables protein carrier chaperone1TASHomo_sapiens(9606)Function
GO:0140662enables ATP-dependent protein folding chaperone1IEAHomo_sapiens(9606)Function
GO:1900226involved_in negative regulation of NLRP3 inflammasome complex assembly1IDAHomo_sapiens(9606)Process
GO:1902904involved_in negative regulation of supramolecular fiber organization1IDAHomo_sapiens(9606)Process
GO:1904589involved_in regulation of protein import1TASHomo_sapiens(9606)Process
GO:1904764involved_in chaperone-mediated autophagy translocation complex disassembly2IBA,ISSHomo_sapiens(9606)Process
GO:1904813located_in ficolin-1-rich granule lumen1TASHomo_sapiens(9606)Component
GO:1990832involved_in slow axonal transport1IBAHomo_sapiens(9606)Process
GO:1990833enables clathrin-uncoating ATPase activity1IBAHomo_sapiens(9606)Function
GO:1990904part_of ribonucleoprotein complex1IDAHomo_sapiens(9606)Component

Expression