Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Metabolic enzyme
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000109819 Gene ID 10891 Accession 9237
Symbol PPARGC1A Alias LEM6;PGC1;PGC1A;PGC-1v;PPARGC1;PGC-1alpha;PGC-1(alpha) Full Name PPARG coactivator 1 alpha
Status Confidence Length 98057 bases Strand Minus strand
Position 4 : 23792021 - 23890077 RNA binding domain RRM_1
Summary The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000481498 RRM_1 PF00076 1.1e-06 1
ENSP00000264867 RRM_1 PF00076 1.4e-06 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
36153371 Regulatory chromatin rewiring promotes metabolic switching during adaptation to oncogenic receptor tyrosine kinase inhibition. Samuel Ogden 2022-10-01 Oncogene

Transcripts

Name Transcript ID bp Protein Translation ID
PPARGC1A-209 ENST00000509702 2704 No protein -
PPARGC1A-201 ENST00000264867 6288 798aa ENSP00000264867
PPARGC1A-204 ENST00000506055 2627 271aa ENSP00000423075
PPARGC1A-211 ENST00000513205 1432 301aa ENSP00000421632
PPARGC1A-208 ENST00000509642 1391 No protein -
PPARGC1A-212 ENST00000514479 324 No protein -
PPARGC1A-207 ENST00000508380 576 No protein -
PPARGC1A-210 ENST00000512169 550 No protein -
PPARGC1A-205 ENST00000507342 359 No protein -
PPARGC1A-215 ENST00000515534 433 No protein -
PPARGC1A-202 ENST00000503714 380 No protein -
PPARGC1A-203 ENST00000505469 406 No protein -
PPARGC1A-214 ENST00000514517 548 No protein -
PPARGC1A-206 ENST00000507380 2385 99aa ENSP00000424181
PPARGC1A-213 ENST00000514494 529 No protein -
PPARGC1A-217 ENST00000613098 3210 671aa ENSP00000481498
PPARGC1A-218 ENST00000617484 1026 297aa ENSP00000477921
PPARGC1A-216 ENST00000612355 936 267aa ENSP00000479729

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
3470Cholesterol, HDL9.11565346408683E-517903299
4704Cholesterol, HDL8.92867062780578E-517903299
5693Blood Pressure5.04278146959727E-617903303
5696Blood Pressure8.19596529333388E-617903303
5706Blood Pressure8.58702893994373E-617903303
5709Blood Pressure1.01477958305285E-517903303
7189Alkaline Phosphatase5.09992075077292E-517903293
13898Myocardial Infarction7.3233145E-004-
15349Heart Failure4.0505419E-004-
16083Stroke3.4733485E-00419369658
17127Blood Pressure1.137e-00519060910
21717Personality3.327e-005-
27447Cardiovascular Physiological Phenomena1.2830000E-005-
27448Cardiovascular Physiological Phenomena4.2550000E-005-
27493Cardiovascular Physiological Phenomena6.5600000E-005-
29635Lipoprotein(a)8.6620000E-005-
29636Lipoprotein(a)4.4610000E-005-
29652Lipoprotein(a)7.7620000E-005-
29655Lipoprotein(a)8.8630000E-005-
30535Monocytes3.4470000E-005-
31639Platelet Count1.2390000E-005-
39633Platelet Function Tests2.8111000E-005-
43602Platelet Function Tests2.3248900E-005-
52328Child Development Disorders, Pervasive4.4000000E-005-
56276Erythrocyte Count6.4500000E-006-
70529Tooth Demineralization2E-623918034
73047Smell9E-626632684
77606Cognition Disorders1E-726252872
77607Cognitive Dysfunction1E-726252872
81953Schizophrenia1E-626198764
84819Emphysema2E-1024383474
86784Gout1E-722179738
94538Cognition Disorders7E-826252872
94539Cognitive Dysfunction7E-826252872
97071Longevity6E-627015805
101605Heart Rate2E-1527798624
105923Essential Tremor1E-927797806

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000109819homo_sapiensENSP0000031264934.408624.6334homo_sapiensENSP0000026486744.110331.5789
ENSG00000109819homo_sapiensENSP0000027807019.531212.5homo_sapiensENSP0000026486740.726826.0652

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000109819homo_sapiensENSP0000026486798.997598.6216nomascus_leucogenysENSNLEP0000004173798.626798.2522
ENSG00000109819homo_sapiensENSP0000026486799.749499.6241pan_paniscusENSPPAP0000002305298.393198.2695
ENSG00000109819homo_sapiensENSP0000026486799.874799.8747pongo_abeliiENSPPYP0000001635799.874799.8747
ENSG00000109819homo_sapiensENSP0000026486799.749499.7494pan_troglodytesENSPTRP0000002747098.393198.3931
ENSG00000109819homo_sapiensENSP0000026486799.749499.7494gorilla_gorillaENSGGOP0000000958699.749499.7494
ENSG00000109819homo_sapiensENSP0000026486792.731888.5965ornithorhynchus_anatinusENSOANP0000004391793.081888.9308
ENSG00000109819homo_sapiensENSP0000026486792.857189.7243sarcophilus_harrisiiENSSHAP0000001168187.279284.3345
ENSG00000109819homo_sapiensENSP0000026486761.027658.6466notamacropus_eugeniiENSMEUP0000000548972.686669.8507
ENSG00000109819homo_sapiensENSP0000026486790.852189.0977choloepus_hoffmanniENSCHOP0000000032591.19589.434
ENSG00000109819homo_sapiensENSP0000026486795.9994.6115dasypus_novemcinctusENSDNOP0000001767795.9994.6115
ENSG00000109819homo_sapiensENSP0000026486793.859692.1053erinaceus_europaeusENSEEUP0000000840296.025694.2308
ENSG00000109819homo_sapiensENSP0000026486787.468783.0827echinops_telfairiENSETEP0000001470189.372684.8912
ENSG00000109819homo_sapiensENSP0000026486799.373498.9975callithrix_jacchusENSCJAP0000004657299.373498.9975
ENSG00000109819homo_sapiensENSP0000026486799.624199.6241cercocebus_atysENSCATP0000001743199.624199.6241
ENSG00000109819homo_sapiensENSP0000026486797.493796.9925macaca_fascicularisENSMFAP0000004576997.007596.5087
ENSG00000109819homo_sapiensENSP0000026486799.498799.2481macaca_mulattaENSMMUP0000006044097.06696.8215
ENSG00000109819homo_sapiensENSP0000026486799.498799.2481macaca_nemestrinaENSMNEP0000000835499.498799.2481
ENSG00000109819homo_sapiensENSP0000026486799.624199.6241papio_anubisENSPANP0000001851899.624199.6241
ENSG00000109819homo_sapiensENSP0000026486799.624199.6241mandrillus_leucophaeusENSMLEP0000002014199.624199.6241
ENSG00000109819homo_sapiensENSP0000026486794.862293.7343tursiops_truncatusENSTTRP0000000503395.100593.9698
ENSG00000109819homo_sapiensENSP0000026486796.992594.9875vulpes_vulpesENSVVUP0000001814994.736892.7785
ENSG00000109819homo_sapiensENSP0000026486796.867294.1103mus_spretusMGP_SPRETEiJ_P007078097.110594.3467
ENSG00000109819homo_sapiensENSP0000026486798.120396.9925equus_asinusENSEASP0000504034696.547595.4377
ENSG00000109819homo_sapiensENSP0000026486796.992594.8622capra_hircusENSCHIP0000001538097.114294.9812
ENSG00000109819homo_sapiensENSP0000026486796.867294.8622loxodonta_africanaENSLAFP0000001085397.110595.1005
ENSG00000109819homo_sapiensENSP0000026486796.992595.8647panthera_leoENSPLOP0000002138897.236296.1055
ENSG00000109819homo_sapiensENSP0000026486788.345987.218ailuropoda_melanoleucaENSAMEP0000001100797.916796.6667
ENSG00000109819homo_sapiensENSP0000026486796.616594.7368bos_indicus_hybridENSBIXP0000501148896.859394.9749
ENSG00000109819homo_sapiensENSP0000026486796.491294.6115oryctolagus_cuniculusENSOCUP0000003488389.534987.7907
ENSG00000109819homo_sapiensENSP0000026486797.243195.7393equus_caballusENSECAP0000006643391.834390.4142
ENSG00000109819homo_sapiensENSP0000026486796.616594.9875canis_lupus_familiarisENSCAFP0084501177589.54788.0372
ENSG00000109819homo_sapiensENSP0000026486796.992595.99panthera_pardusENSPPRP0000000617897.236296.2312
ENSG00000109819homo_sapiensENSP0000026486797.493795.614marmota_marmota_marmotaENSMMMP0000001947797.738795.8543
ENSG00000109819homo_sapiensENSP0000026486796.240694.3609balaenoptera_musculusENSBMSP0001000255196.482494.598
ENSG00000109819homo_sapiensENSP0000026486797.493795.7393cavia_porcellusENSCPOP0000002203697.738795.9799
ENSG00000109819homo_sapiensENSP0000026486795.61494.4862felis_catusENSFCAP0000005472395.018793.8979
ENSG00000109819homo_sapiensENSP0000026486789.097787.218ursus_americanusENSUAMP0000002705993.429791.4586
ENSG00000109819homo_sapiensENSP0000026486793.483790.8521monodelphis_domesticaENSMODP0000000066493.836591.195
ENSG00000109819homo_sapiensENSP0000026486795.61493.7343bison_bison_bisonENSBBBP0000002168995.854393.9698
ENSG00000109819homo_sapiensENSP0000026486796.115394.7368monodon_monocerosENSMMNP0001501196296.356894.9749
ENSG00000109819homo_sapiensENSP0000026486796.741994.7368sus_scrofaENSSSCP0000003243796.984994.9749
ENSG00000109819homo_sapiensENSP0000026486797.869795.8647microcebus_murinusENSMICP0000004554193.757591.8367
ENSG00000109819homo_sapiensENSP0000026486733.333332.4561octodon_degusENSODEP0000001131498.884896.2825
ENSG00000109819homo_sapiensENSP0000026486733.458632.3308jaculus_jaculusENSJJAP0000001655699.256595.9108
ENSG00000109819homo_sapiensENSP0000026486795.864793.609ovis_aries_rambouilletENSOARP0002001873986.148784.1216
ENSG00000109819homo_sapiensENSP0000026486795.61494.4862ursus_maritimusENSUMAP0000000447397.321496.1735
ENSG00000109819homo_sapiensENSP0000026486796.365994.3609ochotona_princepsENSOPRP0000001178196.851494.8363
ENSG00000109819homo_sapiensENSP0000026486796.115394.8622delphinapterus_leucasENSDLEP0000001961296.356895.1005
ENSG00000109819homo_sapiensENSP0000026486796.491294.6115physeter_catodonENSPCTP0000501642196.733794.8492
ENSG00000109819homo_sapiensENSP0000026486796.867294.1103mus_caroliMGP_CAROLIEiJ_P006814697.110594.3467
ENSG00000109819homo_sapiensENSP0000026486797.117894.3609mus_musculusENSMUSP0000011704097.239694.4793
ENSG00000109819homo_sapiensENSP0000026486796.616593.985dipodomys_ordiiENSDORP0000001531396.737894.1029
ENSG00000109819homo_sapiensENSP0000026486796.867295.2381mustela_putorius_furoENSMPUP0000001663297.110595.4774
ENSG00000109819homo_sapiensENSP0000026486798.370997.4937aotus_nancymaaeENSANAP0000003685797.880397.0075
ENSG00000109819homo_sapiensENSP0000026486797.61997.1178saimiri_boliviensis_boliviensisENSSBOP0000000131597.132296.6334
ENSG00000109819homo_sapiensENSP0000026486788.220686.0902vicugna_pacosENSVPAP0000000322288.442286.3065
ENSG00000109819homo_sapiensENSP0000026486799.624199.6241chlorocebus_sabaeusENSCSAP0000001263399.624199.6241
ENSG00000109819homo_sapiensENSP0000026486790.100388.5965tupaia_belangeriENSTBEP0000000444390.100388.5965
ENSG00000109819homo_sapiensENSP0000026486797.117894.4862mesocricetus_auratusENSMAUP0000001113797.361894.7236
ENSG00000109819homo_sapiensENSP0000026486796.365995.1128phocoena_sinusENSPSNP0000002839596.60895.3518
ENSG00000109819homo_sapiensENSP0000026486795.363492.9825camelus_dromedariusENSCDRP0000502324395.244192.8661
ENSG00000109819homo_sapiensENSP0000026486799.373498.9975carlito_syrichtaENSTSYP0000001801599.373498.9975
ENSG00000109819homo_sapiensENSP0000026486796.992595.99panthera_tigris_altaicaENSPTIP0000000508897.236296.2312
ENSG00000109819homo_sapiensENSP0000026486795.739393.2331rattus_norvegicusENSRNOP0000009310197.20194.6565
ENSG00000109819homo_sapiensENSP0000026486798.746997.8697prolemur_simusENSPSMP0000002944698.746997.8697
ENSG00000109819homo_sapiensENSP0000026486796.741994.1103microtus_ochrogasterENSMOCP0000000873196.984994.3467
ENSG00000109819homo_sapiensENSP0000026486790.100388.4712sorex_araneusENSSARP0000000052990.326688.6935
ENSG00000109819homo_sapiensENSP0000026486797.243194.9875peromyscus_maniculatus_bairdiiENSPEMP0000000966997.365195.1067
ENSG00000109819homo_sapiensENSP0000026486796.616594.7368bos_mutusENSBMUP0000001158796.859394.9749
ENSG00000109819homo_sapiensENSP0000026486796.992594.4862mus_spicilegusENSMSIP0000002360595.08692.629
ENSG00000109819homo_sapiensENSP0000026486796.992594.6115cricetulus_griseus_chok1gshdENSCGRP0000101475197.236294.8492
ENSG00000109819homo_sapiensENSP0000026486797.99596.3659pteropus_vampyrusENSPVAP0000000469798.241296.608
ENSG00000109819homo_sapiensENSP0000026486797.243195.614myotis_lucifugusENSMLUP0000001486497.487495.8543
ENSG00000109819homo_sapiensENSP0000026486769.674266.792vombatus_ursinusENSVURP0001000558187.01183.4116
ENSG00000109819homo_sapiensENSP0000026486797.744496.2406rhinolophus_ferrumequinumENSRFEP0001000244897.9996.4824
ENSG00000109819homo_sapiensENSP0000026486796.867295.3634neovison_visonENSNVIP0000001662597.110595.603
ENSG00000109819homo_sapiensENSP0000026486795.488793.4837bos_taurusENSBTAP0000002263693.040391.0867
ENSG00000109819homo_sapiensENSP0000026486797.117895.2381heterocephalus_glaber_femaleENSHGLP0000000978696.633494.7631
ENSG00000109819homo_sapiensENSP0000026486799.373499.3734rhinopithecus_bietiENSRBIP0000001663799.373499.3734
ENSG00000109819homo_sapiensENSP0000026486795.112893.7343canis_lupus_dingoENSCAFP0002003517398.06296.6408
ENSG00000109819homo_sapiensENSP0000026486797.744495.7393sciurus_vulgarisENSSVLP0000501855497.9995.9799
ENSG00000109819homo_sapiensENSP0000026486792.857189.599phascolarctos_cinereusENSPCIP0000002082593.207689.9371
ENSG00000109819homo_sapiensENSP0000026486795.9992.7318procavia_capensisENSPCAP0000001526096.231292.9648
ENSG00000109819homo_sapiensENSP0000026486796.992593.985nannospalax_galiliENSNGAP0000001354497.236294.2211
ENSG00000109819homo_sapiensENSP0000026486796.616594.7368bos_grunniensENSBGRP0000002308496.859394.9749
ENSG00000109819homo_sapiensENSP0000026486797.368495.614chinchilla_lanigeraENSCLAP0000000285997.613195.8543
ENSG00000109819homo_sapiensENSP0000026486796.491294.4862cervus_hanglu_yarkandensisENSCHYP0000003224694.017192.0635
ENSG00000109819homo_sapiensENSP0000026486796.491294.8622catagonus_wagneriENSCWAP0000002876296.733795.1005
ENSG00000109819homo_sapiensENSP0000026486796.867294.6115ictidomys_tridecemlineatusENSSTOP0000002637896.26494.0224
ENSG00000109819homo_sapiensENSP0000026486797.493796.1153otolemur_garnettiiENSOGAP0000001304797.493796.1153
ENSG00000109819homo_sapiensENSP0000026486798.746998.4962cebus_imitatorENSCCAP0000001388097.044396.798
ENSG00000109819homo_sapiensENSP0000026486797.744495.8647urocitellus_parryiiENSUPAP0001002297197.9996.1055
ENSG00000109819homo_sapiensENSP0000026486796.491294.6115moschus_moschiferusENSMMSP0000001881596.612394.7302
ENSG00000109819homo_sapiensENSP0000026486799.498799.4987rhinopithecus_roxellanaENSRROP0000000258199.498799.4987
ENSG00000109819homo_sapiensENSP0000026486796.867294.2356mus_pahariMGP_PahariEiJ_P003134397.110594.4724
ENSG00000109819homo_sapiensENSP0000026486798.621697.4937propithecus_coquereliENSPCOP0000002165597.280696.1681
ENSG00000109819homo_sapiensENSP0000026486733.20817.6692drosophila_melanogasterFBpp007858624.83613.2146
ENSG00000109819homo_sapiensENSP0000026486722.681714.6617eptatretus_burgeriENSEBUP0000002300044.913229.0323
ENSG00000109819homo_sapiensENSP0000026486778.696767.7945callorhinchus_miliiENSCMIP0000002379176.39965.8151
ENSG00000109819homo_sapiensENSP0000026486781.829673.0576latimeria_chalumnaeENSLACP0000001596283.397274.4572
ENSG00000109819homo_sapiensENSP0000026486777.944967.4185lepisosteus_oculatusENSLOCP0000001520774.669964.5858
ENSG00000109819homo_sapiensENSP0000026486767.669257.3935danio_rerioENSDARP0000008848162.863853.3178
ENSG00000109819homo_sapiensENSP0000026486770.80259.7744carassius_auratusENSCARP0000012149849.604941.8788
ENSG00000109819homo_sapiensENSP0000026486770.175459.1479carassius_auratusENSCARP0000004929347.297339.8649
ENSG00000109819homo_sapiensENSP0000026486773.308360.6516astyanax_mexicanusENSAMXP0000003103566.704755.1881
ENSG00000109819homo_sapiensENSP0000026486771.679258.396ictalurus_punctatusENSIPUP0000003007149.438240.2766
ENSG00000109819homo_sapiensENSP0000026486771.428661.4035esox_luciusENSELUP0000001729161.224552.6316
ENSG00000109819homo_sapiensENSP0000026486770.175457.8947electrophorus_electricusENSEEEP0000000744264.293953.0425
ENSG00000109819homo_sapiensENSP0000026486771.929861.2782oncorhynchus_kisutchENSOKIP0000505517560.934251.9108
ENSG00000109819homo_sapiensENSP0000026486771.679261.9048oncorhynchus_kisutchENSOKIP0000500770045.217439.0514
ENSG00000109819homo_sapiensENSP0000026486772.055161.2782oncorhynchus_mykissENSOMYP0000012267345.2438.4736
ENSG00000109819homo_sapiensENSP0000026486771.804561.9048oncorhynchus_mykissENSOMYP0000010175944.453138.3243
ENSG00000109819homo_sapiensENSP0000026486771.929862.406salmo_salarENSSSAP0000016187345.375539.3676
ENSG00000109819homo_sapiensENSP0000026486741.353435.3383salmo_salarENSSSAP0000008732935.560330.3879
ENSG00000109819homo_sapiensENSP0000026486772.055162.406salmo_truttaENSSTUP0000009268845.418639.3365
ENSG00000109819homo_sapiensENSP0000026486772.431161.5288salmo_truttaENSSTUP0000000449660.714351.5756
ENSG00000109819homo_sapiensENSP0000026486771.303360.401fundulus_heteroclitusENSFHEP0000003430044.803237.9528
ENSG00000109819homo_sapiensENSP0000026486771.553960.2757poecilia_reticulataENSPREP0000002836244.470437.4611
ENSG00000109819homo_sapiensENSP0000026486771.679260.401xiphophorus_maculatusENSXMAP0000000778145.110438.0126
ENSG00000109819homo_sapiensENSP0000026486771.553961.1529oryzias_latipesENSORLP0000000602845.031538.4858
ENSG00000109819homo_sapiensENSP0000026486770.300859.6491cyclopterus_lumpusENSCLMP0000502210160.517851.3484
ENSG00000109819homo_sapiensENSP0000026486772.932361.4035oreochromis_niloticusENSONIP0000002713645.327138.162
ENSG00000109819homo_sapiensENSP0000026486772.80761.7794haplochromis_burtoniENSHBUP0000000394945.284538.4256
ENSG00000109819homo_sapiensENSP0000026486771.553960.6516astatotilapia_callipteraENSACLP0000000151444.784337.9608
ENSG00000109819homo_sapiensENSP0000026486773.057662.1554sparus_aurataENSSAUP0001006709145.761438.9325
ENSG00000109819homo_sapiensENSP0000026486773.809562.9073lates_calcariferENSLCAP0001003626561.934852.7865
ENSG00000109819homo_sapiensENSP0000026486784.461276.5664xenopus_tropicalisENSXETP0000006959785.750677.7354
ENSG00000109819homo_sapiensENSP0000026486730.576428.4461chrysemys_picta_belliiENSCPBP0000004069775.776470.4969
ENSG00000109819homo_sapiensENSP0000026486792.731887.8446sphenodon_punctatusENSSPUP0000001759493.081888.1761
ENSG00000109819homo_sapiensENSP0000026486790.476285.4637crocodylus_porosusENSCPRP0000500685692.921587.7735
ENSG00000109819homo_sapiensENSP0000026486725.939822.6817laticauda_laticaudataENSLLTP0000002173968.092159.5395
ENSG00000109819homo_sapiensENSP0000026486746.240639.3484notechis_scutatusENSNSUP0000001434174.545563.4343
ENSG00000109819homo_sapiensENSP0000026486721.303318.0451pseudonaja_textilisENSPTXP0000002076874.889963.4361
ENSG00000109819homo_sapiensENSP0000026486754.511346.6165pseudonaja_textilisENSPTXP0000002076675.78464.8084
ENSG00000109819homo_sapiensENSP0000026486792.355987.3434anas_platyrhynchos_platyrhynchosENSAPLP0000003121988.369383.5731
ENSG00000109819homo_sapiensENSP0000026486791.979986.8421gallus_gallusENSGALP0001001362289.294484.3066
ENSG00000109819homo_sapiensENSP0000026486791.478786.7168meleagris_gallopavoENSMGAP0000001315590.570785.8561
ENSG00000109819homo_sapiensENSP0000026486732.581529.0727serinus_canariaENSSCAP0000000594888.135678.6441
ENSG00000109819homo_sapiensENSP0000026486792.481287.7193parus_majorENSPMJP0000002197492.830288.0503
ENSG00000109819homo_sapiensENSP0000026486789.097783.208anolis_carolinensisENSACAP0000000088889.209583.3124
ENSG00000109819homo_sapiensENSP0000026486767.167957.7694neolamprologus_brichardiENSNBRP0000003077670.433660.5782
ENSG00000109819homo_sapiensENSP0000026486753.759445.614naja_najaENSNNAP0000002202376.334564.7687
ENSG00000109819homo_sapiensENSP0000026486790.476283.8346podarcis_muralisENSPMRP0000001933190.589783.9398
ENSG00000109819homo_sapiensENSP0000026486764.160460.0251geospiza_fortisENSGFOP0000000198190.140884.331
ENSG00000109819homo_sapiensENSP0000026486731.077728.4461geospiza_fortisENSGFOP0000000199490.181882.5455
ENSG00000109819homo_sapiensENSP0000026486791.102885.7143taeniopygia_guttataENSTGUP0000003501390.086784.7584
ENSG00000109819homo_sapiensENSP0000026486774.060264.9123erpetoichthys_calabaricusENSECRP0000000419172.337863.4027
ENSG00000109819homo_sapiensENSP0000026486772.180560.6516kryptolebias_marmoratusENSKMAP0000000718261.276651.4894
ENSG00000109819homo_sapiensENSP0000026486789.849683.0827salvator_merianaeENSSMRP0000000185590.302383.5013
ENSG00000109819homo_sapiensENSP000002648675041.1028oryzias_javanicusENSOJAP0000002690538.402331.5688
ENSG00000109819homo_sapiensENSP0000026486765.162956.391amphilophus_citrinellusENSACIP0000001250769.518760.1604
ENSG00000109819homo_sapiensENSP0000026486772.80762.406dicentrarchus_labraxENSDLAP0000505174244.795738.3963
ENSG00000109819homo_sapiensENSP0000026486768.546459.1479amphiprion_perculaENSAPEP0000003181767.034357.8431
ENSG00000109819homo_sapiensENSP0000026486771.428660.7769oryzias_sinensisENSOSIP0000003619045.059338.3399
ENSG00000109819homo_sapiensENSP0000026486792.857188.0952pelodiscus_sinensisENSPSIP0000001334493.207688.4277
ENSG00000109819homo_sapiensENSP0000026486791.854686.5915gopherus_evgoodeiENSGEVP0000502521592.317487.0277
ENSG00000109819homo_sapiensENSP0000026486790.100384.8371chelonoidis_abingdoniiENSCABP0000003167991.12885.8048
ENSG00000109819homo_sapiensENSP0000026486767.042657.7694seriola_dumeriliENSSDUP0000001014469.390459.7925
ENSG00000109819homo_sapiensENSP0000026486774.060262.6566cottoperca_gobioENSCGOP0000002581746.171939.0625
ENSG00000109819homo_sapiensENSP0000026486793.98589.2231struthio_camelus_australisENSSCUP0000000892994.339689.5597
ENSG00000109819homo_sapiensENSP0000026486790.100384.8371anser_brachyrhynchusENSABRP0000001686789.427984.204
ENSG00000109819homo_sapiensENSP0000026486733.458627.3183gasterosteus_aculeatusENSGACP0000002583854.938344.856
ENSG00000109819homo_sapiensENSP0000026486771.553961.4035cynoglossus_semilaevisENSCSEP0000001074545.245638.8273
ENSG00000109819homo_sapiensENSP0000026486770.426160.0251poecilia_formosaENSPFOP0000000137360.365251.4501
ENSG00000109819homo_sapiensENSP0000026486773.558962.5313myripristis_murdjanENSMMDP0000503102361.273552.0877
ENSG00000109819homo_sapiensENSP0000026486773.18362.1554sander_luciopercaENSSLUP0000005392345.911938.9937
ENSG00000109819homo_sapiensENSP0000026486792.606587.9699strigops_habroptilaENSSHBP0000502087292.95688.3019
ENSG00000109819homo_sapiensENSP0000026486773.18362.6566amphiprion_ocellarisENSAOCP0000000344645.412138.8802
ENSG00000109819homo_sapiensENSP0000026486792.857187.9699terrapene_carolina_triunguisENSTMTP0000000324693.207688.3019
ENSG00000109819homo_sapiensENSP0000026486770.80260.7769hucho_huchoENSHHUP0000001630456.107348.1629
ENSG00000109819homo_sapiensENSP0000026486769.172958.396hucho_huchoENSHHUP0000008184743.533136.7508
ENSG00000109819homo_sapiensENSP0000026486773.057661.5288betta_splendensENSBSLP0000003692557.722848.6139
ENSG00000109819homo_sapiensENSP0000026486773.684261.5288pygocentrus_nattereriENSPNAP0000000393066.742355.7321
ENSG00000109819homo_sapiensENSP0000026486773.558962.406anabas_testudineusENSATEP0000002410261.659752.3109
ENSG00000109819homo_sapiensENSP0000026486770.80260.7769seriola_lalandi_dorsalisENSSLDP0000000884262.36253.532
ENSG00000109819homo_sapiensENSP0000026486770.300859.6491labrus_bergyltaENSLBEP0000002566256.72448.1294
ENSG00000109819homo_sapiensENSP0000026486772.80761.7794pundamilia_nyerereiENSPNYP0000000902245.284538.4256
ENSG00000109819homo_sapiensENSP0000026486772.431162.5313mastacembelus_armatusENSMAMP0000000813060.970552.6371
ENSG00000109819homo_sapiensENSP0000026486772.431161.4035stegastes_partitusENSSPAP0000003137045.333338.4314
ENSG00000109819homo_sapiensENSP0000026486721.679218.6717oncorhynchus_tshawytschaENSOTSP0000510459465.037656.015
ENSG00000109819homo_sapiensENSP0000026486771.929861.1529oncorhynchus_tshawytschaENSOTSP0000510290445.125838.3648
ENSG00000109819homo_sapiensENSP0000026486746.867239.8496oncorhynchus_tshawytschaENSOTSP0000510459041.098934.9451
ENSG00000109819homo_sapiensENSP0000026486773.433662.6566acanthochromis_polyacanthusENSAPOP0000003141445.567638.8802
ENSG00000109819homo_sapiensENSP0000026486793.483788.5965aquila_chrysaetos_chrysaetosENSACCP0002000033493.836588.9308
ENSG00000109819homo_sapiensENSP0000026486771.553959.7744nothobranchius_furzeriENSNFUP0001505002045.102737.6777
ENSG00000109819homo_sapiensENSP0000026486745.9937.594cyprinodon_variegatusENSCVAP0000002904741.143533.6323
ENSG00000109819homo_sapiensENSP0000026486770.676760.2757denticeps_clupeoidesENSDCDP0000001427462.946453.683
ENSG00000109819homo_sapiensENSP0000026486773.18362.0301takifugu_rubripesENSTRUP0000001775144.716737.902
ENSG00000109819homo_sapiensENSP0000026486792.606587.3434ficedula_albicollisENSFALP0000002141792.95687.673
ENSG00000109819homo_sapiensENSP0000026486767.919858.1454hippocampus_comesENSHCOP0000001194759.23550.7104
ENSG00000109819homo_sapiensENSP0000026486771.303360.6516cyprinus_carpio_carpioENSCCRP0000016646949.956142.4934
ENSG00000109819homo_sapiensENSP0000026486770.927359.8997cyprinus_carpio_carpioENSCCRP0000014169948.961941.3495
ENSG00000109819homo_sapiensENSP0000026486791.353486.5915coturnix_japonicaENSCJPP0000502313190.671685.9453
ENSG00000109819homo_sapiensENSP0000026486763.533854.386poecilia_latipinnaENSPLAP0000000171064.916855.5698
ENSG00000109819homo_sapiensENSP0000026486770.927359.8997sinocyclocheilus_grahamiENSSGRP0000005635864.391454.38
ENSG00000109819homo_sapiensENSP0000026486770.676759.2732sinocyclocheilus_grahamiENSSGRP0000004917747.635139.9493
ENSG00000109819homo_sapiensENSP0000026486772.681761.6541maylandia_zebraENSMZEP0000500217345.206538.3476
ENSG00000109819homo_sapiensENSP0000026486719.548917.6692tetraodon_nigroviridisENSTNIP0000000461493.975984.9398
ENSG00000109819homo_sapiensENSP0000026486731.954926.3158tetraodon_nigroviridisENSTNIP0000001426857.562147.4041
ENSG00000109819homo_sapiensENSP0000026486767.293255.2632paramormyrops_kingsleyaeENSPKIP0000001790847.396338.9232
ENSG00000109819homo_sapiensENSP0000026486766.290754.1353paramormyrops_kingsleyaeENSPKIP0000001603447.274438.6059
ENSG00000109819homo_sapiensENSP0000026486768.295755.8897scleropages_formosusENSSFOP0001500242056.652846.3617
ENSG00000109819homo_sapiensENSP0000026486762.40650.1253scleropages_formosusENSSFOP0001502887065.183252.356
ENSG00000109819homo_sapiensENSP0000026486784.335876.0652leptobrachium_leishanenseENSLLEP0000000512385.732577.3248
ENSG00000109819homo_sapiensENSP0000026486772.681761.5288scophthalmus_maximusENSSMAP0000001888645.418938.4495
ENSG00000109819homo_sapiensENSP0000026486770.300859.7744oryzias_melastigmaENSOMEP0000000501460.387551.3455

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000785part_of chromatin1ICHomo_sapiens(9606)Component
GO:0001659involved_in temperature homeostasis1TASHomo_sapiens(9606)Process
GO:0001678involved_in intracellular glucose homeostasis1NASHomo_sapiens(9606)Process
GO:0002021involved_in response to dietary excess1IEAHomo_sapiens(9606)Process
GO:0003677enables DNA binding2ISS,TASHomo_sapiens(9606)Function
GO:0003712enables transcription coregulator activity2ISS,TASHomo_sapiens(9606)Function
GO:0003713enables transcription coactivator activity1IDAHomo_sapiens(9606)Function
GO:0003723enables RNA binding1TASHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus5IBA,IDA,ISS,TASHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0006094involved_in gluconeogenesis2IDA,NASHomo_sapiens(9606)Process
GO:0006355acts_upstream_of_or_within regulation of DNA-templated transcription2IDAHomo_sapiens(9606)Process
GO:0006367involved_in transcription initiation at RNA polymerase II promoter1TASHomo_sapiens(9606)Process
GO:0006397involved_in mRNA processing1TASHomo_sapiens(9606)Process
GO:0007005involved_in mitochondrion organization1NASHomo_sapiens(9606)Process
GO:0007586involved_in digestion1TASHomo_sapiens(9606)Process
GO:0008134enables transcription factor binding1IBAHomo_sapiens(9606)Function
GO:0008380involved_in RNA splicing1TASHomo_sapiens(9606)Process
GO:0010628involved_in positive regulation of gene expression2IDA,IMPHomo_sapiens(9606)Process
GO:0010822involved_in positive regulation of mitochondrion organization2IMP,ISSHomo_sapiens(9606)Process
GO:0014850involved_in response to muscle activity1ISSHomo_sapiens(9606)Process
GO:0016605located_in PML body1IEAHomo_sapiens(9606)Component
GO:0016922enables nuclear receptor binding1IPIHomo_sapiens(9606)Function
GO:0019395involved_in fatty acid oxidation1NASHomo_sapiens(9606)Process
GO:0022904involved_in respiratory electron transport chain1ISSHomo_sapiens(9606)Process
GO:0030374enables nuclear receptor coactivator activity2IBA,IDAHomo_sapiens(9606)Function
GO:0031490enables chromatin DNA binding1ISSHomo_sapiens(9606)Function
GO:0031625enables ubiquitin protein ligase binding1IPIHomo_sapiens(9606)Function
GO:0032922involved_in circadian regulation of gene expression1ISSHomo_sapiens(9606)Process
GO:0034599involved_in cellular response to oxidative stress1ISSHomo_sapiens(9606)Process
GO:0035066involved_in positive regulation of histone acetylation1TASHomo_sapiens(9606)Process
GO:0042594involved_in response to starvation1NASHomo_sapiens(9606)Process
GO:0042752involved_in regulation of circadian rhythm1ISSHomo_sapiens(9606)Process
GO:0043524involved_in negative regulation of neuron apoptotic process1ISSHomo_sapiens(9606)Process
GO:0043565enables sequence-specific DNA binding1IDAHomo_sapiens(9606)Function
GO:0045333involved_in cellular respiration1TASHomo_sapiens(9606)Process
GO:0045722involved_in positive regulation of gluconeogenesis1TASHomo_sapiens(9606)Process
GO:0045893involved_in positive regulation of DNA-templated transcription1IDAHomo_sapiens(9606)Process
GO:0045944involved_in positive regulation of transcription by RNA polymerase II3IBA,IDA,ISSHomo_sapiens(9606)Process
GO:0046321involved_in positive regulation of fatty acid oxidation1TASHomo_sapiens(9606)Process
GO:0048662acts_upstream_of negative regulation of smooth muscle cell proliferation1IMPHomo_sapiens(9606)Process
GO:0050821involved_in protein stabilization1TASHomo_sapiens(9606)Process
GO:0050873involved_in brown fat cell differentiation1TASHomo_sapiens(9606)Process
GO:0051091involved_in positive regulation of DNA-binding transcription factor activity2IBA,IDAHomo_sapiens(9606)Process
GO:0051402involved_in neuron apoptotic process1IEAHomo_sapiens(9606)Process
GO:0060612involved_in adipose tissue development1IEAHomo_sapiens(9606)Process
GO:0061629enables RNA polymerase II-specific DNA-binding transcription factor binding1ISSHomo_sapiens(9606)Function
GO:0065003involved_in protein-containing complex assembly1TASHomo_sapiens(9606)Process
GO:0097009involved_in energy homeostasis1ISSHomo_sapiens(9606)Process
GO:0106222enables lncRNA binding1IEAHomo_sapiens(9606)Function
GO:0120162involved_in positive regulation of cold-induced thermogenesis1ISSHomo_sapiens(9606)Process
GO:0140297enables DNA-binding transcription factor binding1TASHomo_sapiens(9606)Function
GO:1901857involved_in positive regulation of cellular respiration1IEAHomo_sapiens(9606)Process
GO:1901860involved_in positive regulation of mitochondrial DNA metabolic process1IEAHomo_sapiens(9606)Process
GO:1901863involved_in positive regulation of muscle tissue development1IEAHomo_sapiens(9606)Process
GO:2000277involved_in positive regulation of oxidative phosphorylation uncoupler activity1ISSHomo_sapiens(9606)Process
GO:2001171involved_in positive regulation of ATP biosynthetic process1ISSHomo_sapiens(9606)Process

Expression