RBP Type	Non-canonical_RBPs
Diseases	Cancer Disease
Drug	N.A.
Main interacting RNAs	rRNA
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	DataSet_01_311 DataSet_01_315

Ensembl ID	ENSG00000108312	Gene ID	7343	Accession	12511
Symbol	UBTF	Alias	UBF;UBF1;UBF2;UBF-1;CONDBA;NOR-90	Full Name	upstream binding transcription factor
Status	Confidence	Length	16594 bases	Strand	Minus strand
Position	17 : 44205033 - 44221626	RNA binding domain	N.A.
Summary	This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
29300972	A recurrent de novo missense mutation in UBTF causes developmental neuroregression.	Camilo Toro	2018-02-15	Human molecular genetics
37414777	Early maturation and hyperexcitability is a shared phenotype of cortical neurons derived from different ASD-associated mutations.	Yara Hussein	2023-07-06	Translational psychiatry
31479756	Electron tomography reveals changes in spatial distribution of UBTF1 and UBTF2 isoforms within nucleolar components during rRNA synthesis inhibition.	Pavel Tchelidze	2019-11-01	Journal of structural biology
35316324	Concurrent CDX2 cis-deregulation and UBTF::ATXN7L3 fusion define a novel high-risk subtype of B-cell ALL.	Marie Passet	2022-06-16	Blood
35117547	Overview of research on fusion genes in prostate cancer.	Chunjiao Song	2020-03-01	Translational cancer research
29215200	miR-424-5p reduces ribosomal RNA and protein synthesis in muscle wasting.	Martin Connolly	2018-04-01	Journal of cachexia, sarcopenia and muscle

Name	Transcript ID	bp	Protein	Translation ID
UBTF-202	ENST00000343638	4684	727aa	ENSP00000345297
UBTF-201	ENST00000302904	4997	764aa	ENSP00000302640
UBTF-204	ENST00000436088	4795	764aa	ENSP00000390669
UBTF-206	ENST00000527034	3010	745aa	ENSP00000431539
UBTF-213	ENST00000533177	3011	727aa	ENSP00000437180
UBTF-203	ENST00000393606	2683	727aa	ENSP00000377231
UBTF-215	ENST00000704740	2747	610aa	ENSP00000516018
UBTF-218	ENST00000704746	2518	764aa	ENSP00000516023
UBTF-217	ENST00000704742	2338	727aa	ENSP00000516020
UBTF-216	ENST00000704741	2569	764aa	ENSP00000516019
UBTF-205	ENST00000526094	2459	727aa	ENSP00000432925
UBTF-209	ENST00000529383	2570	764aa	ENSP00000435708
UBTF-210	ENST00000529947	685	No protein	-
UBTF-212	ENST00000531368	431	No protein	-
UBTF-208	ENST00000529373	674	194aa	ENSP00000431295
UBTF-207	ENST00000529042	535	No protein	-
UBTF-211	ENST00000530828	721	149aa	ENSP00000433046
UBTF-214	ENST00000537550	1085	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
60718	Erythrocyte Indices	1E-8	28017375
87425	Erythrocyte Indices	4E-7	28017375

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000108312	homo_sapiens	ENSP00000328269	37.5394	19.5584	homo_sapiens	ENSP00000390669	15.5759	8.11518
ENSG00000108312	homo_sapiens	ENSP00000359393	47.5	28	homo_sapiens	ENSP00000390669	12.4346	7.32984
ENSG00000108312	homo_sapiens	ENSP00000505691	31.1828	14.5161	homo_sapiens	ENSP00000390669	7.59162	3.53403
ENSG00000108312	homo_sapiens	ENSP00000296503	43.5407	27.2727	homo_sapiens	ENSP00000390669	11.911	7.46073
ENSG00000108312	homo_sapiens	ENSP00000485108	67.1756	50.3817	homo_sapiens	ENSP00000390669	34.555	25.9162
ENSG00000108312	homo_sapiens	ENSP00000354842	26.0456	12.3574	homo_sapiens	ENSP00000390669	17.9319	8.50785
ENSG00000108312	homo_sapiens	ENSP00000344724	25.4941	13.834	homo_sapiens	ENSP00000390669	16.8848	9.1623
ENSG00000108312	homo_sapiens	ENSP00000343023	16.1582	7.11864	homo_sapiens	ENSP00000390669	18.7173	8.24607
ENSG00000108312	homo_sapiens	ENSP00000219746	25	9.72222	homo_sapiens	ENSP00000390669	18.8482	7.32984
ENSG00000108312	homo_sapiens	ENSP00000397911	22.931	9.82759	homo_sapiens	ENSP00000390669	17.4084	7.46073
ENSG00000108312	homo_sapiens	ENSP00000508468	44.0758	25.1185	homo_sapiens	ENSP00000390669	12.1728	6.93717
ENSG00000108312	homo_sapiens	ENSP00000345347	46.0465	28.8372	homo_sapiens	ENSP00000390669	12.9581	8.11518
ENSG00000108312	homo_sapiens	ENSP00000216106	19.1348	10.4825	homo_sapiens	ENSP00000390669	15.0524	8.24607
ENSG00000108312	homo_sapiens	ENSP00000323967	39.6594	17.7616	homo_sapiens	ENSP00000390669	21.3351	9.55497
ENSG00000108312	homo_sapiens	ENSP00000258381	15.568	5.8906	homo_sapiens	ENSP00000390669	14.5288	5.49738
ENSG00000108312	homo_sapiens	ENSP00000375899	15.6863	6.68973	homo_sapiens	ENSP00000390669	17.801	7.59162
ENSG00000108312	homo_sapiens	ENSP00000278412	36.1072	17.0663	homo_sapiens	ENSP00000390669	33.5079	15.8377
ENSG00000108312	homo_sapiens	ENSP00000336856	34.2939	16.1383	homo_sapiens	ENSP00000390669	15.5759	7.32984
ENSG00000108312	homo_sapiens	ENSP00000393080	25.2818	11.7552	homo_sapiens	ENSP00000390669	20.5497	9.55497
ENSG00000108312	homo_sapiens	ENSP00000420588	26.8293	13.8211	homo_sapiens	ENSP00000390669	8.63874	4.45026

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000108312	homo_sapiens	ENSP00000390669	83.9005	82.8534	nomascus_leucogenys	ENSNLEP00000026942	82.9237	81.8887
ENSG00000108312	homo_sapiens	ENSP00000390669	100	100	pan_paniscus	ENSPPAP00000038584	100	100
ENSG00000108312	homo_sapiens	ENSP00000390669	100	100	pongo_abelii	ENSPPYP00000009374	100	100
ENSG00000108312	homo_sapiens	ENSP00000390669	100	100	pan_troglodytes	ENSPTRP00000075608	100	100
ENSG00000108312	homo_sapiens	ENSP00000390669	100	100	gorilla_gorilla	ENSGGOP00000037612	100	100
ENSG00000108312	homo_sapiens	ENSP00000390669	81.9372	78.6649	ornithorhynchus_anatinus	ENSOANP00000050232	89.0469	85.4908
ENSG00000108312	homo_sapiens	ENSP00000390669	98.2984	94.7644	sarcophilus_harrisii	ENSSHAP00000024595	98.4273	94.8886
ENSG00000108312	homo_sapiens	ENSP00000390669	57.8534	54.5812	notamacropus_eugenii	ENSMEUP00000002636	61.2188	57.7562
ENSG00000108312	homo_sapiens	ENSP00000390669	89.7906	88.7435	dasypus_novemcinctus	ENSDNOP00000000180	99.5646	98.4035
ENSG00000108312	homo_sapiens	ENSP00000390669	85.3403	82.7225	erinaceus_europaeus	ENSEEUP00000010417	87.9892	85.2901
ENSG00000108312	homo_sapiens	ENSP00000390669	64.0052	61.7801	echinops_telfairi	ENSETEP00000009407	81.7726	78.9298
ENSG00000108312	homo_sapiens	ENSP00000390669	99.8691	99.7382	callithrix_jacchus	ENSCJAP00000018681	99.8691	99.7382
ENSG00000108312	homo_sapiens	ENSP00000390669	100	99.8691	cercocebus_atys	ENSCATP00000009242	100	99.8691
ENSG00000108312	homo_sapiens	ENSP00000390669	100	100	macaca_fascicularis	ENSMFAP00000041515	100	100
ENSG00000108312	homo_sapiens	ENSP00000390669	100	100	macaca_mulatta	ENSMMUP00000057261	100	100
ENSG00000108312	homo_sapiens	ENSP00000390669	100	100	macaca_nemestrina	ENSMNEP00000041793	100	100
ENSG00000108312	homo_sapiens	ENSP00000390669	100	100	papio_anubis	ENSPANP00000027543	99.8693	99.8693
ENSG00000108312	homo_sapiens	ENSP00000390669	100	100	mandrillus_leucophaeus	ENSMLEP00000009959	100	100
ENSG00000108312	homo_sapiens	ENSP00000390669	98.5602	97.5131	tursiops_truncatus	ENSTTRP00000009965	99.4716	98.4148
ENSG00000108312	homo_sapiens	ENSP00000390669	87.8272	87.1728	vulpes_vulpes	ENSVVUP00000024037	89.826	89.1566
ENSG00000108312	homo_sapiens	ENSP00000390669	99.8691	97.9058	mus_spretus	MGP_SPRETEiJ_P0031653	99.8691	97.9058
ENSG00000108312	homo_sapiens	ENSP00000390669	94.7644	94.6335	equus_asinus	ENSEASP00005014624	90.387	90.2622
ENSG00000108312	homo_sapiens	ENSP00000390669	98.1675	96.5969	capra_hircus	ENSCHIP00000008431	99.0753	97.4901
ENSG00000108312	homo_sapiens	ENSP00000390669	99.6073	99.4764	loxodonta_africana	ENSLAFP00000027424	99.6073	99.4764
ENSG00000108312	homo_sapiens	ENSP00000390669	99.6073	98.822	panthera_leo	ENSPLOP00000017308	99.6073	98.822
ENSG00000108312	homo_sapiens	ENSP00000390669	99.6073	99.0838	ailuropoda_melanoleuca	ENSAMEP00000019385	99.6073	99.0838
ENSG00000108312	homo_sapiens	ENSP00000390669	98.1675	96.5969	bos_indicus_hybrid	ENSBIXP00005023440	99.0753	97.4901
ENSG00000108312	homo_sapiens	ENSP00000390669	79.712	77.8796	oryctolagus_cuniculus	ENSOCUP00000049324	78.3784	76.5766
ENSG00000108312	homo_sapiens	ENSP00000390669	98.2984	97.644	equus_caballus	ENSECAP00000028461	84.2873	83.7262
ENSG00000108312	homo_sapiens	ENSP00000390669	95.1571	93.7173	canis_lupus_familiaris	ENSCAFP00845011995	71.6256	70.5419
ENSG00000108312	homo_sapiens	ENSP00000390669	99.7382	98.9529	panthera_pardus	ENSPPRP00000019094	99.7382	98.9529
ENSG00000108312	homo_sapiens	ENSP00000390669	99.6073	99.0838	marmota_marmota_marmota	ENSMMMP00000004083	99.6073	99.0838
ENSG00000108312	homo_sapiens	ENSP00000390669	93.7173	92.9319	balaenoptera_musculus	ENSBMSP00010021886	90.9784	90.216
ENSG00000108312	homo_sapiens	ENSP00000390669	99.0838	98.1675	cavia_porcellus	ENSCPOP00000008120	99.2136	98.2962
ENSG00000108312	homo_sapiens	ENSP00000390669	99.7382	98.9529	felis_catus	ENSFCAP00000002807	99.7382	98.9529
ENSG00000108312	homo_sapiens	ENSP00000390669	82.3298	80.6283	ursus_americanus	ENSUAMP00000031754	79.319	77.6797
ENSG00000108312	homo_sapiens	ENSP00000390669	94.6335	90.8377	monodelphis_domestica	ENSMODP00000045991	94.5098	90.719
ENSG00000108312	homo_sapiens	ENSP00000390669	98.1675	96.466	bison_bison_bison	ENSBBBP00000010489	99.0753	97.358
ENSG00000108312	homo_sapiens	ENSP00000390669	98.4293	97.2513	monodon_monoceros	ENSMMNP00015021918	99.3395	98.1506
ENSG00000108312	homo_sapiens	ENSP00000390669	93.3246	92.0157	sus_scrofa	ENSSSCP00000058812	94.9401	93.6085
ENSG00000108312	homo_sapiens	ENSP00000390669	100	99.7382	microcebus_murinus	ENSMICP00000021617	100	99.7382
ENSG00000108312	homo_sapiens	ENSP00000390669	99.2147	97.3822	octodon_degus	ENSODEP00000024710	99.2147	97.3822
ENSG00000108312	homo_sapiens	ENSP00000390669	99.6073	98.822	jaculus_jaculus	ENSJJAP00000014251	99.6073	98.822
ENSG00000108312	homo_sapiens	ENSP00000390669	98.0367	96.466	ovis_aries_rambouillet	ENSOARP00020020201	99.0741	97.4868
ENSG00000108312	homo_sapiens	ENSP00000390669	83.6387	81.8063	ursus_maritimus	ENSUMAP00000018654	91.8103	89.7989
ENSG00000108312	homo_sapiens	ENSP00000390669	91.0995	89.9215	ochotona_princeps	ENSOPRP00000007953	92.8	91.6
ENSG00000108312	homo_sapiens	ENSP00000390669	93.8482	92.4084	delphinapterus_leucas	ENSDLEP00000011158	97.4185	95.9239
ENSG00000108312	homo_sapiens	ENSP00000390669	93.7173	92.5393	physeter_catodon	ENSPCTP00005028930	89.1656	88.0448
ENSG00000108312	homo_sapiens	ENSP00000390669	99.7382	97.644	mus_caroli	MGP_CAROLIEiJ_P0030220	97.6923	95.641
ENSG00000108312	homo_sapiens	ENSP00000390669	99.8691	97.9058	mus_musculus	ENSMUSP00000133844	99.8691	97.9058
ENSG00000108312	homo_sapiens	ENSP00000390669	99.4764	98.822	dipodomys_ordii	ENSDORP00000017530	99.4764	98.822
ENSG00000108312	homo_sapiens	ENSP00000390669	99.7382	99.2147	mustela_putorius_furo	ENSMPUP00000009381	99.7382	99.2147
ENSG00000108312	homo_sapiens	ENSP00000390669	84.6859	83.1152	aotus_nancymaae	ENSANAP00000021169	77.2076	75.7757
ENSG00000108312	homo_sapiens	ENSP00000390669	99.8691	99.6073	saimiri_boliviensis_boliviensis	ENSSBOP00000015894	99.8691	99.6073
ENSG00000108312	homo_sapiens	ENSP00000390669	89.3979	88.8743	chlorocebus_sabaeus	ENSCSAP00000014540	97.4322	96.8616
ENSG00000108312	homo_sapiens	ENSP00000390669	99.4764	97.644	mesocricetus_auratus	ENSMAUP00000024419	99.4764	97.644
ENSG00000108312	homo_sapiens	ENSP00000390669	98.4293	97.3822	phocoena_sinus	ENSPSNP00000023786	99.3395	98.2827
ENSG00000108312	homo_sapiens	ENSP00000390669	99.8691	99.0838	camelus_dromedarius	ENSCDRP00005022248	99.8691	99.0838
ENSG00000108312	homo_sapiens	ENSP00000390669	86.6492	85.6021	carlito_syrichta	ENSTSYP00000022413	95.8032	94.6454
ENSG00000108312	homo_sapiens	ENSP00000390669	95.1571	93.8482	panthera_tigris_altaica	ENSPTIP00000018192	70.6511	69.6793
ENSG00000108312	homo_sapiens	ENSP00000390669	99.8691	98.2984	rattus_norvegicus	ENSRNOP00000063740	99.8691	98.2984
ENSG00000108312	homo_sapiens	ENSP00000390669	53.0105	52.0942	prolemur_simus	ENSPSMP00000011477	79.1016	77.7344
ENSG00000108312	homo_sapiens	ENSP00000390669	99.7382	98.1675	microtus_ochrogaster	ENSMOCP00000022411	99.7382	98.1675
ENSG00000108312	homo_sapiens	ENSP00000390669	99.8691	98.4293	peromyscus_maniculatus_bairdii	ENSPEMP00000006093	99.8691	98.4293
ENSG00000108312	homo_sapiens	ENSP00000390669	98.1675	96.466	bos_mutus	ENSBMUP00000026345	99.0753	97.358
ENSG00000108312	homo_sapiens	ENSP00000390669	94.6335	93.3246	mus_spicilegus	ENSMSIP00000033561	93.1701	91.8814
ENSG00000108312	homo_sapiens	ENSP00000390669	99.8691	98.1675	cricetulus_griseus_chok1gshd	ENSCGRP00001013565	99.8691	98.1675
ENSG00000108312	homo_sapiens	ENSP00000390669	99.7382	98.5602	pteropus_vampyrus	ENSPVAP00000012942	99.7382	98.5602
ENSG00000108312	homo_sapiens	ENSP00000390669	98.0367	96.8586	myotis_lucifugus	ENSMLUP00000001733	97.526	96.3542
ENSG00000108312	homo_sapiens	ENSP00000390669	98.2984	94.6335	vombatus_ursinus	ENSVURP00010010869	98.4273	94.7575
ENSG00000108312	homo_sapiens	ENSP00000390669	99.7382	99.2147	rhinolophus_ferrumequinum	ENSRFEP00010008095	95.9698	95.466
ENSG00000108312	homo_sapiens	ENSP00000390669	94.2408	93.3246	neovison_vison	ENSNVIP00000029403	92.3077	91.4103
ENSG00000108312	homo_sapiens	ENSP00000390669	98.1675	96.5969	bos_taurus	ENSBTAP00000034691	99.0753	97.4901
ENSG00000108312	homo_sapiens	ENSP00000390669	99.3456	97.5131	heterocephalus_glaber_female	ENSHGLP00000009224	99.2157	97.3856
ENSG00000108312	homo_sapiens	ENSP00000390669	100	100	rhinopithecus_bieti	ENSRBIP00000042445	100	100
ENSG00000108312	homo_sapiens	ENSP00000390669	88.6126	87.9581	canis_lupus_dingo	ENSCAFP00020013480	95.8923	95.1841
ENSG00000108312	homo_sapiens	ENSP00000390669	99.7382	99.2147	sciurus_vulgaris	ENSSVLP00005001642	99.7382	99.2147
ENSG00000108312	homo_sapiens	ENSP00000390669	98.2984	94.5026	phascolarctos_cinereus	ENSPCIP00000027039	94.8232	91.1616
ENSG00000108312	homo_sapiens	ENSP00000390669	97.644	96.2042	procavia_capensis	ENSPCAP00000011365	98.0289	96.5834
ENSG00000108312	homo_sapiens	ENSP00000390669	98.6911	96.9895	nannospalax_galili	ENSNGAP00000009960	98.4334	96.7363
ENSG00000108312	homo_sapiens	ENSP00000390669	98.1675	96.466	bos_grunniens	ENSBGRP00000041515	99.0753	97.358
ENSG00000108312	homo_sapiens	ENSP00000390669	91.623	90.1832	chinchilla_lanigera	ENSCLAP00000024059	99.4318	97.8693
ENSG00000108312	homo_sapiens	ENSP00000390669	98.1675	96.466	cervus_hanglu_yarkandensis	ENSCHYP00000001300	99.0753	97.358
ENSG00000108312	homo_sapiens	ENSP00000390669	99.8691	98.9529	catagonus_wagneri	ENSCWAP00000027062	99.8691	98.9529
ENSG00000108312	homo_sapiens	ENSP00000390669	99.6073	99.2147	ictidomys_tridecemlineatus	ENSSTOP00000028724	99.6073	99.2147
ENSG00000108312	homo_sapiens	ENSP00000390669	100	99.6073	otolemur_garnettii	ENSOGAP00000021950	100	99.6073
ENSG00000108312	homo_sapiens	ENSP00000390669	99.7382	99.4764	cebus_imitator	ENSCCAP00000009240	99.7382	99.4764
ENSG00000108312	homo_sapiens	ENSP00000390669	99.6073	99.2147	urocitellus_parryii	ENSUPAP00010002756	99.6073	99.2147
ENSG00000108312	homo_sapiens	ENSP00000390669	98.1675	96.3351	moschus_moschiferus	ENSMMSP00000026443	99.0753	97.2259
ENSG00000108312	homo_sapiens	ENSP00000390669	100	100	rhinopithecus_roxellana	ENSRROP00000021160	100	100
ENSG00000108312	homo_sapiens	ENSP00000390669	99.8691	97.7749	mus_pahari	MGP_PahariEiJ_P0036948	99.8691	97.7749
ENSG00000108312	homo_sapiens	ENSP00000390669	99.8691	99.4764	propithecus_coquereli	ENSPCOP00000030729	99.8691	99.4764
ENSG00000108312	homo_sapiens	ENSP00000390669	27.2251	12.3037	caenorhabditis_elegans	T20B12.8.1	29.8422	13.4864
ENSG00000108312	homo_sapiens	ENSP00000390669	26.178	11.1257	caenorhabditis_elegans	C32F10.5.1	29.0276	12.3367
ENSG00000108312	homo_sapiens	ENSP00000390669	15.9686	6.93717	ciona_intestinalis	ENSCINP00000023739	19.2126	8.34646
ENSG00000108312	homo_sapiens	ENSP00000390669	84.555	73.1675	latimeria_chalumnae	ENSLACP00000019142	85.9043	74.3351
ENSG00000108312	homo_sapiens	ENSP00000390669	81.6754	65.3141	lepisosteus_oculatus	ENSLOCP00000014837	84.6676	67.7069
ENSG00000108312	homo_sapiens	ENSP00000390669	71.8586	60.0785	clupea_harengus	ENSCHAP00000026159	81.454	68.1009
ENSG00000108312	homo_sapiens	ENSP00000390669	80.1047	63.6126	danio_rerio	ENSDARP00000056613	83.2653	66.1225
ENSG00000108312	homo_sapiens	ENSP00000390669	78.9267	64.267	carassius_auratus	ENSCARP00000044050	84.4538	68.7675
ENSG00000108312	homo_sapiens	ENSP00000390669	74.8691	61.6492	carassius_auratus	ENSCARP00000036636	81.4815	67.094
ENSG00000108312	homo_sapiens	ENSP00000390669	72.9058	60.2094	astyanax_mexicanus	ENSAMXP00000055057	82.3964	68.0473
ENSG00000108312	homo_sapiens	ENSP00000390669	79.8429	64.5288	ictalurus_punctatus	ENSIPUP00000036321	82.3212	66.5317
ENSG00000108312	homo_sapiens	ENSP00000390669	80.6283	65.445	esox_lucius	ENSELUP00000023128	82.024	66.5779
ENSG00000108312	homo_sapiens	ENSP00000390669	70.8115	57.199	electrophorus_electricus	ENSEEEP00000002166	76.09	61.4627
ENSG00000108312	homo_sapiens	ENSP00000390669	79.5812	64.5288	oncorhynchus_kisutch	ENSOKIP00005074276	81.5013	66.0858
ENSG00000108312	homo_sapiens	ENSP00000390669	79.3194	64.9215	oncorhynchus_kisutch	ENSOKIP00005080338	82.5613	67.5749
ENSG00000108312	homo_sapiens	ENSP00000390669	79.9738	65.0524	oncorhynchus_mykiss	ENSOMYP00000017892	81.0345	65.9151
ENSG00000108312	homo_sapiens	ENSP00000390669	79.4503	64.6597	oncorhynchus_mykiss	ENSOMYP00000014976	77.0305	62.6904
ENSG00000108312	homo_sapiens	ENSP00000390669	79.5812	64.7906	salmo_salar	ENSSSAP00000147117	80.9587	65.9121
ENSG00000108312	homo_sapiens	ENSP00000390669	14.3979	10.9948	salmo_salar	ENSSSAP00000173567	48.4581	37.0044
ENSG00000108312	homo_sapiens	ENSP00000390669	79.8429	64.7906	salmo_salar	ENSSSAP00000049378	81.0093	65.7371
ENSG00000108312	homo_sapiens	ENSP00000390669	79.712	64.6597	salmo_trutta	ENSSTUP00000001360	76.3158	61.9048
ENSG00000108312	homo_sapiens	ENSP00000390669	79.8429	64.7906	salmo_trutta	ENSSTUP00000027353	80.7947	65.5629
ENSG00000108312	homo_sapiens	ENSP00000390669	79.0576	63.089	gadus_morhua	ENSGMOP00000057993	80.7487	64.4385
ENSG00000108312	homo_sapiens	ENSP00000390669	79.4503	64.3979	fundulus_heteroclitus	ENSFHEP00000000136	82.2493	66.6667
ENSG00000108312	homo_sapiens	ENSP00000390669	79.3194	63.3508	poecilia_reticulata	ENSPREP00000014208	82.337	65.7609
ENSG00000108312	homo_sapiens	ENSP00000390669	79.3194	62.9581	xiphophorus_maculatus	ENSXMAP00000040302	81.8919	65
ENSG00000108312	homo_sapiens	ENSP00000390669	80.2356	64.6597	oryzias_latipes	ENSORLP00000003231	82.726	66.6667
ENSG00000108312	homo_sapiens	ENSP00000390669	75.2618	61.2565	cyclopterus_lumpus	ENSCLMP00005027282	81.6761	66.4773
ENSG00000108312	homo_sapiens	ENSP00000390669	80.7592	63.6126	oreochromis_niloticus	ENSONIP00000063495	83.1536	65.4986
ENSG00000108312	homo_sapiens	ENSP00000390669	80.2356	63.3508	haplochromis_burtoni	ENSHBUP00000025886	82.9499	65.4939
ENSG00000108312	homo_sapiens	ENSP00000390669	72.5131	59.4241	astatotilapia_calliptera	ENSACLP00000037852	82.4405	67.5595
ENSG00000108312	homo_sapiens	ENSP00000390669	79.4503	64.3979	sparus_aurata	ENSSAUP00010065050	82.138	66.5765
ENSG00000108312	homo_sapiens	ENSP00000390669	73.4293	59.2932	lates_calcarifer	ENSLCAP00010013472	81.0694	65.4624
ENSG00000108312	homo_sapiens	ENSP00000390669	94.7644	87.1728	chrysemys_picta_bellii	ENSCPBP00000038659	95.5145	87.8628
ENSG00000108312	homo_sapiens	ENSP00000390669	81.0209	76.0471	sphenodon_punctatus	ENSSPUP00000016468	92.6647	86.9761
ENSG00000108312	homo_sapiens	ENSP00000390669	85.4712	79.712	laticauda_laticaudata	ENSLLTP00000015789	92.3621	86.1386
ENSG00000108312	homo_sapiens	ENSP00000390669	85.4712	79.3194	notechis_scutatus	ENSNSUP00000023716	90.9471	84.4011
ENSG00000108312	homo_sapiens	ENSP00000390669	85.733	79.9738	pseudonaja_textilis	ENSPTXP00000011931	91.4804	85.3352
ENSG00000108312	homo_sapiens	ENSP00000390669	21.3351	19.5026	anas_platyrhynchos_platyrhynchos	ENSAPLP00000007407	78.3654	71.6346
ENSG00000108312	homo_sapiens	ENSP00000390669	93.0628	85.9948	gallus_gallus	ENSGALP00010037584	91.8605	84.8837
ENSG00000108312	homo_sapiens	ENSP00000390669	86.6492	80.7592	meleagris_gallopavo	ENSMGAP00000032131	84.0102	78.2995
ENSG00000108312	homo_sapiens	ENSP00000390669	96.2042	89.5288	serinus_canaria	ENSSCAP00000012825	91.875	85.5
ENSG00000108312	homo_sapiens	ENSP00000390669	96.2042	89.5288	parus_major	ENSPMJP00000024026	91.875	85.5
ENSG00000108312	homo_sapiens	ENSP00000390669	66.4921	54.8429	neolamprologus_brichardi	ENSNBRP00000004844	82.4675	68.0195
ENSG00000108312	homo_sapiens	ENSP00000390669	95.4188	87.6963	naja_naja	ENSNNAP00000019453	95.9211	88.1579
ENSG00000108312	homo_sapiens	ENSP00000390669	85.0785	79.8429	podarcis_muralis	ENSPMRP00000023411	91.4205	85.7947
ENSG00000108312	homo_sapiens	ENSP00000390669	96.2042	89.6597	geospiza_fortis	ENSGFOP00000016896	91.875	85.625
ENSG00000108312	homo_sapiens	ENSP00000390669	96.2042	89.5288	taeniopygia_guttata	ENSTGUP00000024088	91.875	85.5
ENSG00000108312	homo_sapiens	ENSP00000390669	75.7853	62.3037	erpetoichthys_calabaricus	ENSECRP00000031913	83.913	68.9855
ENSG00000108312	homo_sapiens	ENSP00000390669	79.0576	64.267	kryptolebias_marmoratus	ENSKMAP00000013601	81.1828	65.9946
ENSG00000108312	homo_sapiens	ENSP00000390669	95.8115	87.8272	salvator_merianae	ENSSMRP00000008980	96.1892	88.1735
ENSG00000108312	homo_sapiens	ENSP00000390669	80.2356	64.7906	oryzias_javanicus	ENSOJAP00000023746	82.2819	66.443
ENSG00000108312	homo_sapiens	ENSP00000390669	79.1885	62.8272	amphilophus_citrinellus	ENSACIP00000010193	84.1446	66.7594
ENSG00000108312	homo_sapiens	ENSP00000390669	78.9267	64.0052	dicentrarchus_labrax	ENSDLAP00005071946	80.615	65.3743
ENSG00000108312	homo_sapiens	ENSP00000390669	79.9738	64.1361	amphiprion_percula	ENSAPEP00000002149	81.5754	65.4206
ENSG00000108312	homo_sapiens	ENSP00000390669	76.178	62.0419	oryzias_sinensis	ENSOSIP00000039128	82.788	67.4253
ENSG00000108312	homo_sapiens	ENSP00000390669	83.9005	78.9267	gopherus_evgoodei	ENSGEVP00005022663	93.1686	87.6453
ENSG00000108312	homo_sapiens	ENSP00000390669	87.9581	81.0209	chelonoidis_abingdonii	ENSCABP00000006963	95.0495	87.553
ENSG00000108312	homo_sapiens	ENSP00000390669	76.7016	60.6021	seriola_dumerili	ENSSDUP00000031041	79.4038	62.7371
ENSG00000108312	homo_sapiens	ENSP00000390669	78.1414	63.6126	cottoperca_gobio	ENSCGOP00000052691	79.1777	64.4562
ENSG00000108312	homo_sapiens	ENSP00000390669	75.3927	71.466	anser_brachyrhynchus	ENSABRP00000020160	92.9032	88.0645
ENSG00000108312	homo_sapiens	ENSP00000390669	72.5131	59.6859	gasterosteus_aculeatus	ENSGACP00000012686	81.9527	67.4556
ENSG00000108312	homo_sapiens	ENSP00000390669	79.3194	65.1832	cynoglossus_semilaevis	ENSCSEP00000033511	82.2252	67.5712
ENSG00000108312	homo_sapiens	ENSP00000390669	79.5812	63.3508	poecilia_formosa	ENSPFOP00000009012	82.3848	65.5827
ENSG00000108312	homo_sapiens	ENSP00000390669	81.1518	65.0524	myripristis_murdjan	ENSMMDP00005034043	82.777	66.3551
ENSG00000108312	homo_sapiens	ENSP00000390669	9.29319	6.15183	myripristis_murdjan	ENSMMDP00005053966	57.2581	37.9032
ENSG00000108312	homo_sapiens	ENSP00000390669	75	61.1257	sander_lucioperca	ENSSLUP00000018045	82.0917	66.9054
ENSG00000108312	homo_sapiens	ENSP00000390669	91.2304	84.9476	strigops_habroptila	ENSSHBP00005017434	96.4039	89.7649
ENSG00000108312	homo_sapiens	ENSP00000390669	79.8429	64.267	amphiprion_ocellaris	ENSAOCP00000000543	81.66	65.7296
ENSG00000108312	homo_sapiens	ENSP00000390669	86.2565	80.2356	terrapene_carolina_triunguis	ENSTMTP00000022888	88.1016	81.9519
ENSG00000108312	homo_sapiens	ENSP00000390669	79.9738	65.0524	hucho_hucho	ENSHHUP00000069076	82.4561	67.0715
ENSG00000108312	homo_sapiens	ENSP00000390669	79.9738	65.1832	hucho_hucho	ENSHHUP00000081637	80.7133	65.786
ENSG00000108312	homo_sapiens	ENSP00000390669	79.4503	64.6597	betta_splendens	ENSBSLP00000037786	78.8312	64.1558
ENSG00000108312	homo_sapiens	ENSP00000390669	80.3665	65.0524	pygocentrus_nattereri	ENSPNAP00000008392	82.973	67.1622
ENSG00000108312	homo_sapiens	ENSP00000390669	79.3194	64.7906	anabas_testudineus	ENSATEP00000039671	82.337	67.2554
ENSG00000108312	homo_sapiens	ENSP00000390669	16.4921	8.24607	ciona_savignyi	ENSCSAVP00000015780	20.5546	10.2773
ENSG00000108312	homo_sapiens	ENSP00000390669	80.1047	63.7435	seriola_lalandi_dorsalis	ENSSLDP00000030479	83.0394	66.0787
ENSG00000108312	homo_sapiens	ENSP00000390669	75.1309	62.3037	labrus_bergylta	ENSLBEP00000009956	80.9591	67.1368
ENSG00000108312	homo_sapiens	ENSP00000390669	72.3822	59.4241	pundamilia_nyererei	ENSPNYP00000017732	82.2917	67.5595
ENSG00000108312	homo_sapiens	ENSP00000390669	79.5812	64.267	mastacembelus_armatus	ENSMAMP00000046800	79.3734	64.0992
ENSG00000108312	homo_sapiens	ENSP00000390669	76.8325	62.3037	stegastes_partitus	ENSSPAP00000023754	81.7549	66.2953
ENSG00000108312	homo_sapiens	ENSP00000390669	11.911	7.59162	oncorhynchus_tshawytscha	ENSOTSP00005099807	57.5949	36.7089
ENSG00000108312	homo_sapiens	ENSP00000390669	79.5812	64.6597	oncorhynchus_tshawytscha	ENSOTSP00005084102	77.1574	62.6904
ENSG00000108312	homo_sapiens	ENSP00000390669	71.466	59.1623	oncorhynchus_tshawytscha	ENSOTSP00005080254	81.25	67.2619
ENSG00000108312	homo_sapiens	ENSP00000390669	79.712	64.5288	acanthochromis_polyacanthus	ENSAPOP00000031607	79.712	64.5288
ENSG00000108312	homo_sapiens	ENSP00000390669	96.0733	89.3979	aquila_chrysaetos_chrysaetos	ENSACCP00020018450	91.75	85.375
ENSG00000108312	homo_sapiens	ENSP00000390669	78.9267	63.7435	nothobranchius_furzeri	ENSNFUP00015004504	81.2668	65.6334
ENSG00000108312	homo_sapiens	ENSP00000390669	74.2147	59.4241	cyprinodon_variegatus	ENSCVAP00000028937	72.6923	58.2051
ENSG00000108312	homo_sapiens	ENSP00000390669	73.4293	61.1257	denticeps_clupeoides	ENSDCDP00000020093	78.1337	65.0418
ENSG00000108312	homo_sapiens	ENSP00000390669	73.0367	61.2565	denticeps_clupeoides	ENSDCDP00000010392	80.5195	67.5325
ENSG00000108312	homo_sapiens	ENSP00000390669	79.1885	64.0052	larimichthys_crocea	ENSLCRP00005017585	82.3129	66.5306
ENSG00000108312	homo_sapiens	ENSP00000390669	79.5812	65.5759	takifugu_rubripes	ENSTRUP00000042707	82.7211	68.1633
ENSG00000108312	homo_sapiens	ENSP00000390669	94.6335	87.9581	ficedula_albicollis	ENSFALP00000001625	87.3188	81.1594
ENSG00000108312	homo_sapiens	ENSP00000390669	79.712	64.9215	hippocampus_comes	ENSHCOP00000018832	81.965	66.7564
ENSG00000108312	homo_sapiens	ENSP00000390669	73.9529	61.1257	cyprinus_carpio_carpio	ENSCCRP00000018671	78.2548	64.6814
ENSG00000108312	homo_sapiens	ENSP00000390669	74.3456	59.6859	cyprinus_carpio_carpio	ENSCCRP00000018975	81.0271	65.0499
ENSG00000108312	homo_sapiens	ENSP00000390669	75.7853	69.3717	coturnix_japonica	ENSCJPP00005024510	71.1302	65.1106
ENSG00000108312	homo_sapiens	ENSP00000390669	18.8482	17.5393	coturnix_japonica	ENSCJPP00005025011	84.7059	78.8235
ENSG00000108312	homo_sapiens	ENSP00000390669	79.5812	63.3508	poecilia_latipinna	ENSPLAP00000013479	82.3848	65.5827
ENSG00000108312	homo_sapiens	ENSP00000390669	81.0209	65.5759	sinocyclocheilus_grahami	ENSSGRP00000043593	83.5358	67.6113
ENSG00000108312	homo_sapiens	ENSP00000390669	79.712	65.5759	sinocyclocheilus_grahami	ENSSGRP00000053724	83.1967	68.4426
ENSG00000108312	homo_sapiens	ENSP00000390669	66.3613	54.712	maylandia_zebra	ENSMZEP00005030914	82.3052	67.8571
ENSG00000108312	homo_sapiens	ENSP00000390669	77.2251	63.7435	tetraodon_nigroviridis	ENSTNIP00000003319	81.2672	67.0799
ENSG00000108312	homo_sapiens	ENSP00000390669	81.8063	67.801	paramormyrops_kingsleyae	ENSPKIP00000011641	84.3455	69.9055
ENSG00000108312	homo_sapiens	ENSP00000390669	71.8586	52.8796	paramormyrops_kingsleyae	ENSPKIP00000038668	68.2836	50.2488
ENSG00000108312	homo_sapiens	ENSP00000390669	55.2356	42.5393	scleropages_formosus	ENSSFOP00015024619	73.2639	56.4236
ENSG00000108312	homo_sapiens	ENSP00000390669	79.0576	65.9686	scleropages_formosus	ENSSFOP00015052807	84.7125	70.6872
ENSG00000108312	homo_sapiens	ENSP00000390669	76.9633	62.5654	scophthalmus_maximus	ENSSMAP00000067466	78.7149	63.9893
ENSG00000108312	homo_sapiens	ENSP00000390669	80.3665	64.5288	oryzias_melastigma	ENSOMEP00000034144	82.638	66.3526

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0001164	enables RNA polymerase I core promoter sequence-specific DNA binding	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0001165	enables RNA polymerase I cis-regulatory region sequence-specific DNA binding	1	IDA	Homo_sapiens(9606)	Function
GO:0001181	enables RNA polymerase I general transcription initiation factor activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0001188	involved_in RNA polymerase I preinitiation complex assembly	1	IEA	Homo_sapiens(9606)	Process
GO:0001650	located_in fibrillar center	1	IDA	Homo_sapiens(9606)	Component
GO:0003682	enables chromatin binding	1	IDA	Homo_sapiens(9606)	Function
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	TAS	Homo_sapiens(9606)	Component
GO:0005730	located_in nucleolus	2	IDA,ISS	Homo_sapiens(9606)	Component
GO:0006360	involved_in transcription by RNA polymerase I	2	IBA,IMP	Homo_sapiens(9606)	Process
GO:0006361	involved_in transcription initiation at RNA polymerase I promoter	1	IDA	Homo_sapiens(9606)	Process
GO:0045943	involved_in positive regulation of transcription by RNA polymerase I	2	IBA,ISS	Homo_sapiens(9606)	Process
GO:0097110	enables scaffold protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:1902659	NOT involved_in regulation of glucose mediated signaling pathway	1	IDA	Homo_sapiens(9606)	Process