Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000107290 Gene ID 23064 Accession 445
Symbol SETX Alias ALS4;AOA2;STEX;Sen1;SCAN2;SCAR1;bA479K20.2 Full Name senataxin
Status Confidence Length 93631 bases Strand Minus strand
Position 9 : 132261356 - 132354986 RNA binding domain UvrD-helicase
Summary This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4). [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000409143 UvrD-helicase PF00580 7.2e-08 1
ENSP00000224140 UvrD-helicase PF00580 0.00031 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
25822250 Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis. S Matthew Miller 2015-05-01 Nature immunology
34263556 SUMOylated Senataxin functions in genome stability, RNA degradation, and stress granule disassembly, and is linked with inherited ataxia and motor neuron disease. L Craig Bennett 2021-12-01 Molecular genetics & genomic medicine
26231220 A new model to study neurodegeneration in ataxia oculomotor apraxia type 2. J Olivier Becherel 2015-10-15 Human molecular genetics
30642639 Germ cell arrest associated with aSETX mutation in ataxia oculomotor apraxia type 2. R S Catford 2019-06-01 Reproductive biomedicine online
36438189 Ataxia with oculomotor apraxia type 2 caused by a novel homozygous mutation in SETX gene, and literature review. Shuaishuai Chen 2022-01-01 Frontiers in molecular neuroscience
29725819 Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients. L Craig Bennett 2018-09-01 Acta neuropathologica
34232287 Catalytically inactive, purified RNase H1: A specific and sensitive probe for RNA-DNA hybrid imaging. P Magdalena Crossley 2021-09-06 The Journal of cell biology
28408439 Sen1 has unique structural features grafted on the architecture of the Upf1-like helicase family. Bronislava Leonaitė 2017-06-01 The EMBO journal

Transcripts

Name Transcript ID bp Protein Translation ID
SETX-205 ENST00000477049 4067 No protein -
SETX-202 ENST00000436441 5730 948aa ENSP00000409143
SETX-201 ENST00000224140 11101 2677aa ENSP00000224140
SETX-203 ENST00000464133 631 No protein -
SETX-204 ENST00000474172 719 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
1003Body Height5.94457947962116E-517903300
13253Lupus Erythematosus, Systemic1.06E-518204446

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000107290homo_sapiensENSP0000015647128.956213.3333homo_sapiensENSP0000022414016.06287.39634
ENSG00000107290homo_sapiensENSP0000027624132.575810.9848homo_sapiensENSP000002241403.212551.0833
ENSG00000107290homo_sapiensENSP0000025507840.181321.853homo_sapiensENSP0000022414014.90478.10609
ENSG00000107290homo_sapiensENSP0000041740125.934312.0423homo_sapiensENSP0000022414025.663111.9163
ENSG00000107290homo_sapiensENSP0000035118536.509418.5849homo_sapiensENSP0000022414014.45657.35898
ENSG00000107290homo_sapiensENSP0000037941220.69869.59333homo_sapiensENSP0000022414014.836.87337
ENSG00000107290homo_sapiensENSP0000035152420.339910.2472homo_sapiensENSP0000022414014.75537.43369
ENSG00000107290homo_sapiensENSP0000026279430.80116.3501homo_sapiensENSP0000022414013.93357.39634
ENSG00000107290homo_sapiensENSP0000026280331.842618.5152homo_sapiensENSP0000022414013.29857.73254
ENSG00000107290homo_sapiensENSP0000035865931.106715.7527homo_sapiensENSP0000022414011.65485.90213

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000107290homo_sapiensENSP0000022414093.612391.8192nomascus_leucogenysENSNLEP0000001559197.282695.4193
ENSG00000107290homo_sapiensENSP0000022414098.954198.2443pan_paniscusENSPPAP0000000105299.250798.5388
ENSG00000107290homo_sapiensENSP0000022414098.393797.1236pongo_abeliiENSPPYP0000002209998.35797.0874
ENSG00000107290homo_sapiensENSP0000022414098.954198.2443pan_troglodytesENSPTRP0000004345099.287998.5757
ENSG00000107290homo_sapiensENSP0000022414097.758797.161gorilla_gorillaENSGGOP0000001817498.79298.188
ENSG00000107290homo_sapiensENSP0000022414066.380352.0732ornithorhynchus_anatinusENSOANP0000004831164.594750.6725
ENSG00000107290homo_sapiensENSP0000022414073.328460.5529sarcophilus_harrisiiENSSHAP0000002198671.04658.6681
ENSG00000107290homo_sapiensENSP0000022414053.492744.3033notamacropus_eugeniiENSMEUP0000001386353.194744.0565
ENSG00000107290homo_sapiensENSP0000022414074.411767.5383choloepus_hoffmanniENSCHOP0000000239575.198268.2522
ENSG00000107290homo_sapiensENSP0000022414087.822280.65dasypus_novemcinctusENSDNOP0000001304487.822280.65
ENSG00000107290homo_sapiensENSP0000022414058.759852.7083erinaceus_europaeusENSEEUP0000000827260.360754.1443
ENSG00000107290homo_sapiensENSP0000022414059.61953.4927echinops_telfairiENSETEP0000000660060.135653.9563
ENSG00000107290homo_sapiensENSP0000022414093.350889.3164callithrix_jacchusENSCJAP0000007827592.350388.3592
ENSG00000107290homo_sapiensENSP0000022414095.778993.2387cercocebus_atysENSCATP0000004108696.645394.0822
ENSG00000107290homo_sapiensENSP0000022414097.011694.8076macaca_fascicularisENSMFAP0000005996195.407893.2403
ENSG00000107290homo_sapiensENSP0000022414096.899594.5835macaca_mulattaENSMMUP0000005020295.332693.054
ENSG00000107290homo_sapiensENSP0000022414094.732992.1928macaca_nemestrinaENSMNEP0000001289295.87993.3081
ENSG00000107290homo_sapiensENSP0000022414096.936994.5088papio_anubisENSPANP0000002175695.369392.9805
ENSG00000107290homo_sapiensENSP0000022414096.862294.3967mandrillus_leucophaeusENSMLEP0000003430596.717694.2559
ENSG00000107290homo_sapiensENSP0000022414078.035169.4061tursiops_truncatusENSTTRP0000001152977.831669.225
ENSG00000107290homo_sapiensENSP0000022414087.710179.9029vulpes_vulpesENSVVUP0000003983786.007378.3516
ENSG00000107290homo_sapiensENSP0000022414081.957471.2738mus_spretusMGP_SPRETEiJ_P005264982.792472
ENSG00000107290homo_sapiensENSP0000022414089.577981.5839equus_asinusENSEASP0000501409589.544481.5534
ENSG00000107290homo_sapiensENSP0000022414085.1776.2794capra_hircusENSCHIP0000002295185.746576.7958
ENSG00000107290homo_sapiensENSP0000022414042.883838.7374loxodonta_africanaENSLAFP0000001453889.617580.9524
ENSG00000107290homo_sapiensENSP0000022414085.580977.923panthera_leoENSPLOP0000003047885.837478.1566
ENSG00000107290homo_sapiensENSP0000022414089.054981.2477ailuropoda_melanoleucaENSAMEP0000004056688.591680.825
ENSG00000107290homo_sapiensENSP0000022414085.543576.7277bos_indicus_hybridENSBIXP0000503144885.352276.5561
ENSG00000107290homo_sapiensENSP0000022414078.595469.3687oryctolagus_cuniculusENSOCUP0000000488079.396270.0755
ENSG00000107290homo_sapiensENSP0000022414089.503281.5465equus_caballusENSECAP0000008597888.153180.3164
ENSG00000107290homo_sapiensENSP0000022414088.158480.4258canis_lupus_familiarisENSCAFP0084502379687.37579.7112
ENSG00000107290homo_sapiensENSP0000022414085.543577.8483panthera_pardusENSPPRP0000002233085.799978.0817
ENSG00000107290homo_sapiensENSP0000022414087.48679.1558marmota_marmota_marmotaENSMMMP0000001268887.781179.4228
ENSG00000107290homo_sapiensENSP0000022414087.784879.6414balaenoptera_musculusENSBMSP0001002996387.686679.5522
ENSG00000107290homo_sapiensENSP0000022414081.882771.3859cavia_porcellusENSCPOP0000000134882.37571.8151
ENSG00000107290homo_sapiensENSP0000022414085.468877.8857felis_catusENSFCAP0000003177185.72578.1191
ENSG00000107290homo_sapiensENSP0000022414089.540581.4344ursus_americanusENSUAMP0000000534689.041680.9807
ENSG00000107290homo_sapiensENSP0000022414073.92661.0758monodelphis_domesticaENSMODP0000005645270.577758.3096
ENSG00000107290homo_sapiensENSP0000022414085.468876.7277bison_bison_bisonENSBBBP0000000060686.047477.2471
ENSG00000107290homo_sapiensENSP0000022414087.635478.8569monodon_monocerosENSMMNP0001501995787.276878.5342
ENSG00000107290homo_sapiensENSP0000022414084.945876.0553sus_scrofaENSSSCP0000005863085.456676.5126
ENSG00000107290homo_sapiensENSP0000022414088.494681.7706microcebus_murinusENSMICP0000003503588.461581.7401
ENSG00000107290homo_sapiensENSP0000022414089.503281.3597ursus_maritimusENSUMAP0000002306489.004580.9064
ENSG00000107290homo_sapiensENSP0000022414058.087451.1393ochotona_princepsENSOPRP0000000271359.10352.0334
ENSG00000107290homo_sapiensENSP0000022414087.48678.8196delphinapterus_leucasENSDLEP0000000671787.225378.5847
ENSG00000107290homo_sapiensENSP0000022414086.215978.0351physeter_catodonENSPCTP0000500800187.29279.0091
ENSG00000107290homo_sapiensENSP0000022414081.695970.975mus_caroliMGP_CAROLIEiJ_P005062082.809571.9424
ENSG00000107290homo_sapiensENSP0000022414082.069571.4232mus_musculusENSMUSP0000005149283.03172.26
ENSG00000107290homo_sapiensENSP0000022414088.158479.7908mustela_putorius_furoENSMPUP0000001244787.99479.6421
ENSG00000107290homo_sapiensENSP0000022414093.238789.3538aotus_nancymaaeENSANAP0000002056993.203989.3204
ENSG00000107290homo_sapiensENSP0000022414093.238788.8681saimiri_boliviensis_boliviensisENSSBOP0000002503193.238788.8681
ENSG00000107290homo_sapiensENSP0000022414079.006372.0209vicugna_pacosENSVPAP0000000926187.941880.1663
ENSG00000107290homo_sapiensENSP0000022414096.899594.5835chlorocebus_sabaeusENSCSAP0000001102496.827294.5129
ENSG00000107290homo_sapiensENSP0000022414069.92963.2051tupaia_belangeriENSTBEP0000000008571.889464.977
ENSG00000107290homo_sapiensENSP0000022414080.239169.4434mesocricetus_auratusENSMAUP0000000053782.488571.3902
ENSG00000107290homo_sapiensENSP0000022414087.784878.8943phocoena_sinusENSPSNP0000001422087.490778.6299
ENSG00000107290homo_sapiensENSP0000022414086.96378.5954camelus_dromedariusENSCDRP0000500642887.584679.1573
ENSG00000107290homo_sapiensENSP0000022414025.700423.5338carlito_syrichtaENSTSYP0000001639381.036574.2049
ENSG00000107290homo_sapiensENSP0000022414085.468877.7363panthera_tigris_altaicaENSPTIP0000002526185.72577.9693
ENSG00000107290homo_sapiensENSP0000022414081.28570.7135rattus_norvegicusENSRNOP0000008285180.532970.0592
ENSG00000107290homo_sapiensENSP0000022414088.083781.8454prolemur_simusENSPSMP0000002371588.182581.9372
ENSG00000107290homo_sapiensENSP0000022414076.428865.7079microtus_ochrogasterENSMOCP0000000110980.172468.9263
ENSG00000107290homo_sapiensENSP0000022414044.004537.9529sorex_araneusENSSARP0000000220049.978843.1056
ENSG00000107290homo_sapiensENSP0000022414081.882772.0956peromyscus_maniculatus_bairdiiENSPEMP0000000131082.998973.0784
ENSG00000107290homo_sapiensENSP0000022414082.853974.0381bos_mutusENSBMUP0000000649185.769576.6435
ENSG00000107290homo_sapiensENSP0000022414081.994871.2365mus_spicilegusENSMSIP0000001140382.736571.8809
ENSG00000107290homo_sapiensENSP0000022414082.33171.8341cricetulus_griseus_chok1gshdENSCGRP0000100119683.643372.9791
ENSG00000107290homo_sapiensENSP0000022414083.787874.9346pteropus_vampyrusENSPVAP0000001440583.662874.8228
ENSG00000107290homo_sapiensENSP0000022414081.210371.0123myotis_lucifugusENSMLUP0000000441981.790871.5199
ENSG00000107290homo_sapiensENSP0000022414073.739361.1505vombatus_ursinusENSVURP0001001618271.677659.4408
ENSG00000107290homo_sapiensENSP0000022414083.376973.8887rhinolophus_ferrumequinumENSRFEP0001001945083.595574.0824
ENSG00000107290homo_sapiensENSP0000022414088.158479.9402neovison_visonENSNVIP0000002378388.026979.821
ENSG00000107290homo_sapiensENSP0000022414085.618276.6903bos_taurusENSBTAP0000007328085.426876.5188
ENSG00000107290homo_sapiensENSP0000022414084.422975.2335heterocephalus_glaber_femaleENSHGLP0000003672684.202775.0373
ENSG00000107290homo_sapiensENSP0000022414094.583591.9686rhinopithecus_bietiENSRBIP0000003356995.367292.7307
ENSG00000107290homo_sapiensENSP0000022414088.046380.2017canis_lupus_dingoENSCAFP0002003142387.555779.7548
ENSG00000107290homo_sapiensENSP0000022414087.822279.9029sciurus_vulgarisENSSVLP0000502251188.085480.1424
ENSG00000107290homo_sapiensENSP0000022414073.104260.8143phascolarctos_cinereusENSPCIP0000002632372.001559.897
ENSG00000107290homo_sapiensENSP0000022414075.046766.8659procavia_capensisENSPCAP0000000995575.611667.3692
ENSG00000107290homo_sapiensENSP0000022414085.057976.0926bos_grunniensENSBGRP0000002298985.989476.926
ENSG00000107290homo_sapiensENSP0000022414081.621272.0583chinchilla_lanigeraENSCLAP0000001835884.558874.6517
ENSG00000107290homo_sapiensENSP0000022414085.917177.1759cervus_hanglu_yarkandensisENSCHYP0000003614285.756977.0321
ENSG00000107290homo_sapiensENSP0000022414085.356776.653catagonus_wagneriENSCWAP0000000788686.226477.434
ENSG00000107290homo_sapiensENSP0000022414087.336679.0063ictidomys_tridecemlineatusENSSTOP0000001982886.336878.1019
ENSG00000107290homo_sapiensENSP0000022414088.942881.8454otolemur_garnettiiENSOGAP0000001199788.022280.9982
ENSG00000107290homo_sapiensENSP0000022414093.313489.3164cebus_imitatorENSCCAP0000002523193.278689.2831
ENSG00000107290homo_sapiensENSP0000022414087.448679.1558urocitellus_parryiiENSUPAP0001001426786.671678.4524
ENSG00000107290homo_sapiensENSP0000022414085.28276.2421moschus_moschiferusENSMMSP0000001234485.537776.4706
ENSG00000107290homo_sapiensENSP0000022414096.675494.4341rhinopithecus_roxellanaENSRROP0000003393596.639394.3988
ENSG00000107290homo_sapiensENSP0000022414081.845471.4606mus_pahariMGP_PahariEiJ_P006164182.866972.3525
ENSG00000107290homo_sapiensENSP0000022414088.531981.808propithecus_coquereliENSPCOP0000002079088.56581.8386
ENSG00000107290homo_sapiensENSP000002241408.554354.14643caenorhabditis_elegansC41D11.6.126.877913.0282
ENSG00000107290homo_sapiensENSP000002241408.92794.93089caenorhabditis_elegansC41D11.7.138.2421.12
ENSG00000107290homo_sapiensENSP0000022414010.1986.12626caenorhabditis_elegansY106G6D.5a.140.384624.2604
ENSG00000107290homo_sapiensENSP0000022414011.91635.97684caenorhabditis_elegansF43G6.1.129.84114.9673
ENSG00000107290homo_sapiensENSP0000022414012.36466.4251drosophila_melanogasterFBpp007135030.090915.6364
ENSG00000107290homo_sapiensENSP0000022414015.65188.10609drosophila_melanogasterFBpp029295931.432916.2791
ENSG00000107290homo_sapiensENSP000002241409.114685.49122drosophila_melanogasterFBpp028950531.937219.2408
ENSG00000107290homo_sapiensENSP0000022414012.62615.71535ciona_intestinalisENSCINP0000001152034.384515.5646
ENSG00000107290homo_sapiensENSP0000022414010.315.0056ciona_intestinalisENSCINP0000002185132.624115.8392
ENSG00000107290homo_sapiensENSP000002241402.913712.01718petromyzon_marinusENSPMAP0000000165034.977624.2152
ENSG00000107290homo_sapiensENSP0000022414017.594310.2727eptatretus_burgeriENSEBUP0000000561546.679927.2547
ENSG00000107290homo_sapiensENSP0000022414054.165137.5047callorhinchus_miliiENSCMIP0000003237752.045936.0373
ENSG00000107290homo_sapiensENSP0000022414046.544633.022latimeria_chalumnaeENSLACP0000002063257.55240.8314
ENSG00000107290homo_sapiensENSP0000022414049.869334.068lepisosteus_oculatusENSLOCP0000000510255.671438.0317
ENSG00000107290homo_sapiensENSP0000022414045.013130.0336clupea_harengusENSCHAP0000005774052.414134.9717
ENSG00000107290homo_sapiensENSP0000022414014.94217.39634danio_rerioENSDARP0000010330729.027614.3687
ENSG00000107290homo_sapiensENSP0000022414045.013129.9216danio_rerioENSDARP0000012437950.886833.826
ENSG00000107290homo_sapiensENSP0000022414045.573430.7807carassius_auratusENSCARP0000001913852.608935.5326
ENSG00000107290homo_sapiensENSP0000022414036.346723.4217carassius_auratusENSCARP0000013607150.756432.7074
ENSG00000107290homo_sapiensENSP0000022414044.602228.7262astyanax_mexicanusENSAMXP0000001485151.310733.0468
ENSG00000107290homo_sapiensENSP0000022414044.26629.9216ictalurus_punctatusENSIPUP0000000983650.814834.3482
ENSG00000107290homo_sapiensENSP0000022414044.751629.6601esox_luciusENSELUP0000004157852.520834.8093
ENSG00000107290homo_sapiensENSP0000022414044.153928.7262esox_luciusENSELUP0000002360052.603534.2234
ENSG00000107290homo_sapiensENSP0000022414046.395229.9963oncorhynchus_kisutchENSOKIP0000506095251.153233.0725
ENSG00000107290homo_sapiensENSP0000022414046.768830.183oncorhynchus_mykissENSOMYP0000000561951.143833.0065
ENSG00000107290homo_sapiensENSP0000022414041.165526.5969salmo_salarENSSSAP0000007151553.625334.6472
ENSG00000107290homo_sapiensENSP0000022414046.05929.8468salmo_truttaENSSTUP0000011039250.326532.6122
ENSG00000107290homo_sapiensENSP0000022414015.3537.58312oryzias_latipesENSORLP0000001310929.441314.5415
ENSG00000107290homo_sapiensENSP0000022414013.18646.61188cyclopterus_lumpusENSCLMP0000503018633.176716.6353
ENSG00000107290homo_sapiensENSP0000022414015.12897.58312oreochromis_niloticusENSONIP0000004712527.682813.8756
ENSG00000107290homo_sapiensENSP0000022414015.16627.58312haplochromis_burtoniENSHBUP0000003195028.979314.4897
ENSG00000107290homo_sapiensENSP0000022414014.75537.32163astatotilapia_callipteraENSACLP0000001232027.875813.832
ENSG00000107290homo_sapiensENSP0000022414015.16627.5084sparus_aurataENSSAUP0001006353029.335314.5231
ENSG00000107290homo_sapiensENSP0000022414015.50247.58312lates_calcariferENSLCAP0001005629429.474414.4176
ENSG00000107290homo_sapiensENSP0000022414058.087443.1827xenopus_tropicalisENSXETP0000007553461.341245.6016
ENSG00000107290homo_sapiensENSP0000022414064.064349.7572chrysemys_picta_belliiENSCPBP0000003013659.923146.5409
ENSG00000107290homo_sapiensENSP0000022414059.693746.6567sphenodon_punctatusENSSPUP0000002165861.508948.0754
ENSG00000107290homo_sapiensENSP0000022414057.751245.7975crocodylus_porosusENSCPRP0000500919764.632151.2542
ENSG00000107290homo_sapiensENSP0000022414054.57638.9615laticauda_laticaudataENSLLTP0000001871058.3741.67
ENSG00000107290homo_sapiensENSP0000022414050.989936.4214notechis_scutatusENSNSUP0000002797256.756840.5405
ENSG00000107290homo_sapiensENSP0000022414052.745637.3179pseudonaja_textilisENSPTXP0000000894757.16640.4453
ENSG00000107290homo_sapiensENSP0000022414061.561547.3665anas_platyrhynchos_platyrhynchosENSAPLP0000001618058.543545.0444
ENSG00000107290homo_sapiensENSP0000022414061.262646.0217gallus_gallusENSGALP0001004288458.550543.9843
ENSG00000107290homo_sapiensENSP0000022414061.262646.1711meleagris_gallopavoENSMGAP0000000592558.823544.3329
ENSG00000107290homo_sapiensENSP0000022414059.09644.8263serinus_canariaENSSCAP0000000498859.630645.2318
ENSG00000107290homo_sapiensENSP0000022414060.067245.2746parus_majorENSPMJP0000000825658.72944.2659
ENSG00000107290homo_sapiensENSP0000022414035.188624.0568anolis_carolinensisENSACAP0000001406355.411837.8824
ENSG00000107290homo_sapiensENSP0000022414053.044538.065naja_najaENSNNAP0000002755658.750542.1597
ENSG00000107290homo_sapiensENSP0000022414049.495736.0478podarcis_muralisENSPMRP0000003586759.63143.4293
ENSG00000107290homo_sapiensENSP0000022414049.981337.4673geospiza_fortisENSGFOP0000001504558.123443.5708
ENSG00000107290homo_sapiensENSP0000022414059.805845.0878taeniopygia_guttataENSTGUP0000002050857.015742.9843
ENSG00000107290homo_sapiensENSP0000022414051.73735.1139erpetoichthys_calabaricusENSECRP0000003081056.255138.1803
ENSG00000107290homo_sapiensENSP0000022414053.828938.8868salvator_merianaeENSSMRP0000000955556.245140.6323
ENSG00000107290homo_sapiensENSP0000022414015.16627.47105dicentrarchus_labraxENSDLAP0000506984428.814814.1945
ENSG00000107290homo_sapiensENSP0000022414014.56857.32163amphiprion_perculaENSAPEP0000000909029.70314.9276
ENSG00000107290homo_sapiensENSP0000022414015.16627.47105oryzias_sinensisENSOSIP0000002138229.721814.6413
ENSG00000107290homo_sapiensENSP0000022414063.503949.7198gopherus_evgoodeiENSGEVP0000501005358.884746.1032
ENSG00000107290homo_sapiensENSP0000022414062.943649.421chelonoidis_abingdoniiENSCABP0000000945659.667146.8484
ENSG00000107290homo_sapiensENSP0000022414015.42777.65783seriola_dumeriliENSSDUP0000000004829.374114.5804
ENSG00000107290homo_sapiensENSP0000022414014.68067.28427cottoperca_gobioENSCGOP0000003665629.089614.4338
ENSG00000107290homo_sapiensENSP0000022414014.97957.39634cottoperca_gobioENSCGOP0000003675830.173114.8984
ENSG00000107290homo_sapiensENSP0000022414061.561547.0303struthio_camelus_australisENSSCUP0000000344059.174145.2065
ENSG00000107290homo_sapiensENSP0000022414061.972447.3665anser_brachyrhynchusENSABRP0000002528958.746544.9008
ENSG00000107290homo_sapiensENSP0000022414013.48526.53717gasterosteus_aculeatusENSGACP0000002125635.116717.0233
ENSG00000107290homo_sapiensENSP0000022414013.74676.98543cynoglossus_semilaevisENSCSEP0000002227031.054915.7806
ENSG00000107290homo_sapiensENSP0000022414012.96236.68659sander_luciopercaENSSLUP0000004148933.820717.4464
ENSG00000107290homo_sapiensENSP0000022414058.236844.901strigops_habroptilaENSSHBP0000501652961.840547.6795
ENSG00000107290homo_sapiensENSP0000022414015.46517.58312amphiprion_ocellarisENSAOCP0000003110729.320114.3768
ENSG00000107290homo_sapiensENSP0000022414064.13949.944terrapene_carolina_triunguisENSTMTP0000002932159.99346.7156
ENSG00000107290homo_sapiensENSP0000022414042.958527.4935hucho_huchoENSHHUP0000004122252.201533.409
ENSG00000107290homo_sapiensENSP0000022414015.16627.43369betta_splendensENSBSLP0000003262328.896814.1637
ENSG00000107290homo_sapiensENSP0000022414045.834930.3325pygocentrus_nattereriENSPNAP0000002122151.082433.8052
ENSG00000107290homo_sapiensENSP0000022414012.14055.75271ciona_savignyiENSCSAVP0000001712132.597815.4463
ENSG00000107290homo_sapiensENSP0000022414017.81859.11468saccharomyces_cerevisiaeYHR164C31.340316.0315
ENSG00000107290homo_sapiensENSP0000022414016.58578.36758saccharomyces_cerevisiaeYLR430W19.901410.0403
ENSG00000107290homo_sapiensENSP0000022414015.42777.65783seriola_lalandi_dorsalisENSSLDP0000003356929.39514.5907
ENSG00000107290homo_sapiensENSP0000022414014.97957.32163labrus_bergyltaENSLBEP0000001143628.97414.1618
ENSG00000107290homo_sapiensENSP0000022414013.18646.61188pundamilia_nyerereiENSPNYP0000002159034.073417.0849
ENSG00000107290homo_sapiensENSP0000022414013.59736.79866stegastes_partitusENSSPAP0000001731434.865917.433
ENSG00000107290homo_sapiensENSP0000022414047.067630.2951oncorhynchus_tshawytschaENSOTSP0000503235651.053532.8606
ENSG00000107290homo_sapiensENSP0000022414013.07436.53717acanthochromis_polyacanthusENSAPOP0000001852935.105317.5527
ENSG00000107290homo_sapiensENSP0000022414061.337345.947aquila_chrysaetos_chrysaetosENSACCP0002002059758.22743.617
ENSG00000107290homo_sapiensENSP0000022414015.31577.54576cyprinodon_variegatusENSCVAP0000002552830.191514.8748
ENSG00000107290homo_sapiensENSP0000022414045.461329.9216denticeps_clupeoidesENSDCDP0000001611053.051434.9172
ENSG00000107290homo_sapiensENSP0000022414015.27837.69518larimichthys_croceaENSLCRP0000504398630.029415.1248
ENSG00000107290homo_sapiensENSP0000022414015.31577.65783takifugu_rubripesENSTRUP0000006079629.796514.8983
ENSG00000107290homo_sapiensENSP0000022414059.768445.1625ficedula_albicollisENSFALP0000002027052.219339.4582
ENSG00000107290homo_sapiensENSP0000022414014.86747.54576hippocampus_comesENSHCOP0000002473130.498115.4789
ENSG00000107290homo_sapiensENSP0000022414046.021730.3325cyprinus_carpio_carpioENSCCRP0000012009951.764734.1176
ENSG00000107290homo_sapiensENSP0000022414045.274628.9877cyprinus_carpio_carpioENSCCRP0000017778252.672833.7245
ENSG00000107290homo_sapiensENSP0000022414059.73144.8637coturnix_japonicaENSCJPP0000500684458.357743.8321
ENSG00000107290homo_sapiensENSP0000022414046.357930.3325sinocyclocheilus_grahamiENSSGRP0000009326252.921134.6269
ENSG00000107290homo_sapiensENSP0000022414035.001923.7579sinocyclocheilus_grahamiENSSGRP0000004938754.224536.8056
ENSG00000107290homo_sapiensENSP0000022414015.09157.54576maylandia_zebraENSMZEP0000501519728.836514.4183
ENSG00000107290homo_sapiensENSP0000022414013.41056.7613tetraodon_nigroviridisENSTNIP0000001679135.161617.7277
ENSG00000107290homo_sapiensENSP0000022414046.656731.9014paramormyrops_kingsleyaeENSPKIP0000001045152.390935.8221
ENSG00000107290homo_sapiensENSP0000022414048.748632.3496scleropages_formosusENSSFOP0001500420353.970235.8147
ENSG00000107290homo_sapiensENSP0000022414054.874940.9414leptobrachium_leishanenseENSLLEP0000004489458.316843.5093
ENSG00000107290homo_sapiensENSP0000022414013.1496.53717scophthalmus_maximusENSSMAP0000005379734.174816.9903

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000165involved_in MAPK cascade1IDAHomo_sapiens(9606)Process
GO:0000228located_in nuclear chromosome1IDAHomo_sapiens(9606)Component
GO:0000781located_in chromosome, telomeric region1IEAHomo_sapiens(9606)Component
GO:0001147enables transcription termination site sequence-specific DNA binding2IBA,IDAHomo_sapiens(9606)Function
GO:0003677enables DNA binding1ICHomo_sapiens(9606)Function
GO:0003678enables DNA helicase activity1TASHomo_sapiens(9606)Function
GO:0003723enables RNA binding1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IEAHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005730located_in nucleolus1IEAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0006302involved_in double-strand break repair1IDAHomo_sapiens(9606)Process
GO:0006310involved_in DNA recombination1IEAHomo_sapiens(9606)Process
GO:0006353involved_in DNA-templated transcription termination1IMPHomo_sapiens(9606)Process
GO:0006369involved_in termination of RNA polymerase II transcription1IBAHomo_sapiens(9606)Process
GO:0006376involved_in mRNA splice site recognition1IMPHomo_sapiens(9606)Process
GO:0006396involved_in RNA processing1TASHomo_sapiens(9606)Process
GO:0006974involved_in DNA damage response1IDAHomo_sapiens(9606)Process
GO:0007283involved_in spermatogenesis1IEAHomo_sapiens(9606)Process
GO:0007399involved_in nervous system development1IEAHomo_sapiens(9606)Process
GO:0007623involved_in circadian rhythm1IEAHomo_sapiens(9606)Process
GO:0008543involved_in fibroblast growth factor receptor signaling pathway1IDAHomo_sapiens(9606)Process
GO:0010976involved_in positive regulation of neuron projection development1IDAHomo_sapiens(9606)Process
GO:0016604is_active_in nuclear body2IBA,IDAHomo_sapiens(9606)Component
GO:0016787enables hydrolase activity1IEAHomo_sapiens(9606)Function
GO:0030154involved_in cell differentiation1IEAHomo_sapiens(9606)Process
GO:0030424located_in axon1IDAHomo_sapiens(9606)Component
GO:0030426located_in growth cone1IDAHomo_sapiens(9606)Component
GO:0032508involved_in DNA duplex unwinding1IEAHomo_sapiens(9606)Process
GO:0033120involved_in positive regulation of RNA splicing1IMPHomo_sapiens(9606)Process
GO:0034599involved_in cellular response to oxidative stress1IDAHomo_sapiens(9606)Process
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0043066involved_in negative regulation of apoptotic process1IDAHomo_sapiens(9606)Process
GO:0043491involved_in protein kinase B signaling1IDAHomo_sapiens(9606)Process
GO:0044344involved_in cellular response to fibroblast growth factor stimulus1IDAHomo_sapiens(9606)Process
GO:0045171located_in intercellular bridge1IDAHomo_sapiens(9606)Component
GO:0045944involved_in positive regulation of transcription by RNA polymerase II1IMPHomo_sapiens(9606)Process
GO:0060566involved_in positive regulation of termination of DNA-templated transcription1IMPHomo_sapiens(9606)Process
GO:0070301involved_in cellular response to hydrogen peroxide1IDAHomo_sapiens(9606)Process
GO:0071300involved_in cellular response to retinoic acid1IDAHomo_sapiens(9606)Process
GO:2000144involved_in positive regulation of DNA-templated transcription initiation1IMPHomo_sapiens(9606)Process
GO:2000806involved_in positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled1IMPHomo_sapiens(9606)Process

Expression