Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerSARS-COV-2
Drug Drug
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations Stress granucleP-body
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000106211 Gene ID 3315 Accession 5246
Symbol HSPB1 Alias CMT2F;HMN2B;HSP27;HSP28;Hsp25;SRP27;HS.76067;HEL-S-102 Full Name heat shock protein family B (small) member 1
Status Confidence Length 1623 bases Strand Plus strand
Position 7 : 76302673 - 76304295 RNA binding domain N.A.
Summary This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. [provided by RefSeq, Aug 2017]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
28077174 Mutant HSPB1 causes loss of translational repression by binding to PCBP1, an RNA binding protein with a possible role in neurodegenerative disease. Thomas Geuens 2017-01-11 Acta neuropathologica communications
36075972 Heat-shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition. Shan Lu 2022-09-01 Nature cell biology
35477000 Characterization and functional interrogation of the SARS-CoV-2 RNA interactome. Athéna Labeau 2022-04-26 Cell reports

Transcripts

Name Transcript ID bp Protein Translation ID
HSPB1-219 ENST00000676398 434 No protein -
HSPB1-212 ENST00000675488 435 No protein -
HSPB1-214 ENST00000675624 434 No protein -
HSPB1-205 ENST00000674560 436 No protein -
HSPB1-215 ENST00000675733 435 No protein -
HSPB1-201 ENST00000248553 777 205aa ENSP00000248553
HSPB1-208 ENST00000674965 802 122aa ENSP00000501765
HSPB1-206 ENST00000674638 772 157aa ENSP00000502651
HSPB1-204 ENST00000674547 800 143aa ENSP00000502461
HSPB1-210 ENST00000675226 776 162aa ENSP00000502510
HSPB1-213 ENST00000675538 812 174aa ENSP00000502495
HSPB1-218 ENST00000676231 807 215aa ENSP00000502249
HSPB1-209 ENST00000675134 756 198aa ENSP00000501831
HSPB1-216 ENST00000675906 794 143aa ENSP00000502714
HSPB1-203 ENST00000447574 1455 No protein -
HSPB1-207 ENST00000674650 687 141aa ENSP00000501628
HSPB1-211 ENST00000675417 1089 No protein -
HSPB1-217 ENST00000676195 144 No protein -
HSPB1-202 ENST00000429938 527 37aa ENSP00000405285

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
37976Platelet Function Tests2.9969500E-005-
62650Multiple Sclerosis6E-621654844
69863S-(3-hydroxypropyl)cysteine N-acetate2E-626053186
69864Smoking2E-626053186
77963Multiple Sclerosis8E-621654844

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000106211homo_sapiensENSP000003033944830.6667homo_sapiensENSP0000024855335.12222.439
ENSG00000106211homo_sapiensENSP0000049908255.428642.2857homo_sapiensENSP0000024855347.317136.0976
ENSG00000106211homo_sapiensENSP0000029155456.069441.6185homo_sapiensENSP0000024855347.317135.122
ENSG00000106211homo_sapiensENSP0000000498253.7539.375homo_sapiensENSP0000024855341.951230.7317
ENSG00000106211homo_sapiensENSP000002819385037.2449homo_sapiensENSP0000024855347.804935.6098
ENSG00000106211homo_sapiensENSP0000031011141.176524.1176homo_sapiensENSP0000024855334.146320
ENSG00000106211homo_sapiensENSP0000030247652.197834.0659homo_sapiensENSP0000024855346.341530.2439
ENSG00000106211homo_sapiensENSP0000045801830.188719.4969homo_sapiensENSP0000024855323.414615.122

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000106211homo_sapiensENSP00000248553100100pan_paniscusENSPPAP00000029479100100
ENSG00000106211homo_sapiensENSP0000024855399.024498.5366pongo_abeliiENSPPYP0000002461899.024498.5366
ENSG00000106211homo_sapiensENSP00000248553100100pan_troglodytesENSPTRP00000033044100100
ENSG00000106211homo_sapiensENSP00000248553100100gorilla_gorillaENSGGOP00000002660100100
ENSG00000106211homo_sapiensENSP0000024855383.414676.5854ornithorhynchus_anatinusENSOANP0000003727081.042774.4076
ENSG00000106211homo_sapiensENSP0000024855387.804978.0488sarcophilus_harrisiiENSSHAP0000002993882.949373.7327
ENSG00000106211homo_sapiensENSP0000024855386.829378.0488notamacropus_eugeniiENSMEUP0000001279785.167576.555
ENSG00000106211homo_sapiensENSP0000024855390.731786.3415dasypus_novemcinctusENSDNOP0000002141092.537388.0597
ENSG00000106211homo_sapiensENSP0000024855361.463457.561erinaceus_europaeusENSEEUP0000000409992.647186.7647
ENSG00000106211homo_sapiensENSP0000024855355.12253.6585echinops_telfairiENSETEP0000000096190.488
ENSG00000106211homo_sapiensENSP0000024855397.56193.6585callithrix_jacchusENSCJAP0000002999697.56193.6585
ENSG00000106211homo_sapiensENSP0000024855398.536698.5366cercocebus_atysENSCATP0000001981298.536698.5366
ENSG00000106211homo_sapiensENSP0000024855363.414657.0732macaca_fascicularisENSMFAP0000006092543.046438.7417
ENSG00000106211homo_sapiensENSP00000248553100100macaca_mulattaENSMMUP00000075911100100
ENSG00000106211homo_sapiensENSP00000248553100100macaca_nemestrinaENSMNEP00000003247100100
ENSG00000106211homo_sapiensENSP00000248553100100papio_anubisENSPANP00000017585100100
ENSG00000106211homo_sapiensENSP0000024855399.512299.5122papio_anubisENSPANP0000005179999.512299.5122
ENSG00000106211homo_sapiensENSP0000024855393.658589.2683vulpes_vulpesENSVVUP0000003281793.203988.835
ENSG00000106211homo_sapiensENSP0000024855391.707384.3902mus_spretusMGP_SPRETEiJ_P007412289.952282.7751
ENSG00000106211homo_sapiensENSP0000024855373.170764.8781equus_asinusENSEASP0000504498068.493160.7306
ENSG00000106211homo_sapiensENSP0000024855391.707388.2927capra_hircusENSCHIP0000001527793.532390.0498
ENSG00000106211homo_sapiensENSP0000024855394.146391.2195panthera_leoENSPLOP0000003063694.146391.2195
ENSG00000106211homo_sapiensENSP0000024855393.658590.2439ailuropoda_melanoleucaENSAMEP0000002151092.753689.372
ENSG00000106211homo_sapiensENSP0000024855390.243986.3415bos_indicus_hybridENSBIXP0000503029792.039888.0597
ENSG00000106211homo_sapiensENSP0000024855395.121991.2195oryctolagus_cuniculusENSOCUP0000001091795.588291.6667
ENSG00000106211homo_sapiensENSP0000024855381.463477.561equus_caballusENSECAP0000002397188.359884.127
ENSG00000106211homo_sapiensENSP0000024855393.658589.2683canis_lupus_familiarisENSCAFP0084500627493.203988.835
ENSG00000106211homo_sapiensENSP0000024855394.146391.2195panthera_pardusENSPPRP0000001352294.146391.2195
ENSG00000106211homo_sapiensENSP0000024855363.414661.4634marmota_marmota_marmotaENSMMMP0000001225862.560.5769
ENSG00000106211homo_sapiensENSP0000024855390.243986.8293balaenoptera_musculusENSBMSP0001002895492.039888.5572
ENSG00000106211homo_sapiensENSP0000024855389.756186.8293cavia_porcellusENSCPOP000000326189289
ENSG00000106211homo_sapiensENSP0000024855393.658590.7317felis_catusENSFCAP0000001878193.658590.7317
ENSG00000106211homo_sapiensENSP0000024855394.146390.7317ursus_americanusENSUAMP0000001410493.236789.8551
ENSG00000106211homo_sapiensENSP0000024855387.317178.5366monodelphis_domesticaENSMODP0000001708869.921962.8906
ENSG00000106211homo_sapiensENSP0000024855390.243986.3415bison_bison_bisonENSBBBP0000001844492.039888.0597
ENSG00000106211homo_sapiensENSP0000024855390.243986.8293monodon_monocerosENSMMNP0001501073892.039888.5572
ENSG00000106211homo_sapiensENSP0000024855392.682988.7805sus_scrofaENSSSCP0000000821682.251178.7879
ENSG00000106211homo_sapiensENSP0000024855392.682986.8293microcebus_murinusENSMICP0000000973392.23386.4078
ENSG00000106211homo_sapiensENSP0000024855389.268386.3415octodon_degusENSODEP0000002133091.588.5
ENSG00000106211homo_sapiensENSP0000024855383.414679.5122jaculus_jaculusENSJJAP0000002117080.281776.5258
ENSG00000106211homo_sapiensENSP0000024855391.219587.8049ovis_aries_rambouilletENSOARP0002003075593.034889.5522
ENSG00000106211homo_sapiensENSP000002485536056.0976ursus_maritimusENSUMAP0000001723142.413839.6552
ENSG00000106211homo_sapiensENSP0000024855392.195188.2927ochotona_princepsENSOPRP0000000732192.647188.7255
ENSG00000106211homo_sapiensENSP0000024855390.243986.8293delphinapterus_leucasENSDLEP0000001075092.039888.5572
ENSG00000106211homo_sapiensENSP0000024855390.243986.8293physeter_catodonENSPCTP0000502251292.039888.5572
ENSG00000106211homo_sapiensENSP0000024855391.707384.3902mus_musculusENSMUSP0000000507789.952282.7751
ENSG00000106211homo_sapiensENSP0000024855386.341579.5122dipodomys_ordiiENSDORP0000001255388.581.5
ENSG00000106211homo_sapiensENSP0000024855393.170789.2683mustela_putorius_furoENSMPUP0000001588992.270588.4058
ENSG00000106211homo_sapiensENSP0000024855394.634190.2439aotus_nancymaaeENSANAP0000003914886.222282.2222
ENSG00000106211homo_sapiensENSP0000024855397.073294.1463aotus_nancymaaeENSANAP0000004176897.073294.1463
ENSG00000106211homo_sapiensENSP0000024855373.170767.8049saimiri_boliviensis_boliviensisENSSBOP0000003206073.891668.4729
ENSG00000106211homo_sapiensENSP0000024855363.414660.4878vicugna_pacosENSVPAP0000000577963.414660.4878
ENSG00000106211homo_sapiensENSP0000024855369.756169.7561chlorocebus_sabaeusENSCSAP00000014155100100
ENSG00000106211homo_sapiensENSP0000024855389.268384.3902tupaia_belangeriENSTBEP0000001263888.83583.9806
ENSG00000106211homo_sapiensENSP0000024855393.658585.8537mesocricetus_auratusENSMAUP0000002196390.56683.0189
ENSG00000106211homo_sapiensENSP0000024855390.243986.8293phocoena_sinusENSPSNP0000000766692.039888.5572
ENSG00000106211homo_sapiensENSP0000024855390.731786.8293camelus_dromedariusENSCDRP0000501084392.537388.5572
ENSG00000106211homo_sapiensENSP0000024855390.243982.9268rattus_norvegicusENSRNOP0000003290289.805882.5243
ENSG00000106211homo_sapiensENSP0000024855391.707386.8293prolemur_simusENSPSMP0000001815991.262186.4078
ENSG00000106211homo_sapiensENSP0000024855389.268381.9512microtus_ochrogasterENSMOCP0000001183587.980880.7692
ENSG00000106211homo_sapiensENSP0000024855392.682984.3902peromyscus_maniculatus_bairdiiENSPEMP0000001079690.909182.7751
ENSG00000106211homo_sapiensENSP0000024855390.243985.8537bos_mutusENSBMUP0000000985792.039887.5622
ENSG00000106211homo_sapiensENSP0000024855391.707384.3902mus_spicilegusENSMSIP0000001414089.952282.7751
ENSG00000106211homo_sapiensENSP0000024855391.707384.3902cricetulus_griseus_chok1gshdENSCGRP0000101475088.262981.2207
ENSG00000106211homo_sapiensENSP0000024855392.682988.7805pteropus_vampyrusENSPVAP0000000321791.787487.9227
ENSG00000106211homo_sapiensENSP0000024855391.707385.3659myotis_lucifugusENSMLUP0000001426790.821384.5411
ENSG00000106211homo_sapiensENSP0000024855387.317178.5366vombatus_ursinusENSVURP0001000419482.110173.8532
ENSG00000106211homo_sapiensENSP0000024855391.219585.8537rhinolophus_ferrumequinumENSRFEP0001001196690.338285.0242
ENSG00000106211homo_sapiensENSP0000024855393.658589.7561neovison_visonENSNVIP0000000439692.753688.8889
ENSG00000106211homo_sapiensENSP0000024855390.243986.3415bos_taurusENSBTAP0000004189892.039888.0597
ENSG00000106211homo_sapiensENSP0000024855388.780584.3902heterocephalus_glaber_femaleENSHGLP0000005346088.349583.9806
ENSG00000106211homo_sapiensENSP0000024855399.024498.5366rhinopithecus_bietiENSRBIP0000001224599.024498.5366
ENSG00000106211homo_sapiensENSP0000024855393.658589.2683canis_lupus_dingoENSCAFP0002001630891.86687.5598
ENSG00000106211homo_sapiensENSP0000024855393.170790.7317sciurus_vulgarisENSSVLP0000502618493.170790.7317
ENSG00000106211homo_sapiensENSP0000024855386.829378.0488phascolarctos_cinereusENSPCIP0000002438781.651473.3945
ENSG00000106211homo_sapiensENSP0000024855392.195187.8049procavia_capensisENSPCAP0000001288290.865486.5385
ENSG00000106211homo_sapiensENSP0000024855393.170783.9024nannospalax_galiliENSNGAP0000002306191.387682.2967
ENSG00000106211homo_sapiensENSP0000024855361.951257.0732bos_grunniensENSBGRP0000001323247.565543.8202
ENSG00000106211homo_sapiensENSP0000024855389.756186.3415chinchilla_lanigeraENSCLAP000000011049288.5
ENSG00000106211homo_sapiensENSP0000024855390.731786.3415cervus_hanglu_yarkandensisENSCHYP0000001563392.537388.0597
ENSG00000106211homo_sapiensENSP0000024855392.682987.8049catagonus_wagneriENSCWAP0000001791891.787486.9565
ENSG00000106211homo_sapiensENSP0000024855389.268386.3415ictidomys_tridecemlineatusENSSTOP0000001918290.594187.6238
ENSG00000106211homo_sapiensENSP0000024855388.780583.4146otolemur_garnettiiENSOGAP0000000673991.919286.3636
ENSG00000106211homo_sapiensENSP0000024855381.951278.5366cebus_imitatorENSCCAP0000001972987.958184.2932
ENSG00000106211homo_sapiensENSP0000024855397.073293.6585cebus_imitatorENSCCAP0000002031097.073293.6585
ENSG00000106211homo_sapiensENSP0000024855389.268386.3415urocitellus_parryiiENSUPAP0001001947090.594187.6238
ENSG00000106211homo_sapiensENSP0000024855390.731786.8293moschus_moschiferusENSMMSP0000000888092.537388.5572
ENSG00000106211homo_sapiensENSP0000024855399.024499.0244rhinopithecus_roxellanaENSRROP0000000157399.024499.0244
ENSG00000106211homo_sapiensENSP0000024855399.512299.5122rhinopithecus_roxellanaENSRROP0000003219999.512299.5122
ENSG00000106211homo_sapiensENSP0000024855391.219583.4146mus_pahariMGP_PahariEiJ_P005960289.473781.8182
ENSG00000106211homo_sapiensENSP0000024855393.170787.8049propithecus_coquereliENSPCOP0000003076092.718487.3786
ENSG00000106211homo_sapiensENSP000002485534024.3902caenorhabditis_elegansC09B8.6a.137.442922.8311
ENSG00000106211homo_sapiensENSP0000024855329.268317.561caenorhabditis_elegansT22A3.2b.153.571432.1429
ENSG00000106211homo_sapiensENSP0000024855327.804918.0488caenorhabditis_elegansC14B9.1.151.818233.6364
ENSG00000106211homo_sapiensENSP0000024855330.243916.0976caenorhabditis_elegansF08H9.3.142.176922.449
ENSG00000106211homo_sapiensENSP0000024855331.707318.0488caenorhabditis_elegansT27E4.8.144.827625.5172
ENSG00000106211homo_sapiensENSP0000024855334.146319.5122caenorhabditis_elegansF08H9.4a.147.61927.2109
ENSG00000106211homo_sapiensENSP0000024855331.707318.0488caenorhabditis_elegansT27E4.2.144.827625.5172
ENSG00000106211homo_sapiensENSP0000024855332.682918.5366caenorhabditis_elegansY46H3A.3a.146.206926.2069
ENSG00000106211homo_sapiensENSP0000024855330.731720.9756caenorhabditis_elegansT27E4.3.144.055930.0699
ENSG00000106211homo_sapiensENSP0000024855330.731720.9756caenorhabditis_elegansT27E4.9.144.055930.0699
ENSG00000106211homo_sapiensENSP0000024855328.780520caenorhabditis_elegansY46H3A.2.141.258728.6713
ENSG00000106211homo_sapiensENSP0000024855338.536624.3902drosophila_melanogasterFBpp007450341.145826.0417
ENSG00000106211homo_sapiensENSP0000024855354.634140ciona_intestinalisENSCINP0000000114958.947443.1579
ENSG00000106211homo_sapiensENSP0000024855367.804954.6341eptatretus_burgeriENSEBUP0000000609559.656748.0687
ENSG00000106211homo_sapiensENSP0000024855373.658558.5366callorhinchus_miliiENSCMIP0000004082067.410753.5714
ENSG00000106211homo_sapiensENSP0000024855382.43972.6829latimeria_chalumnaeENSLACP0000000822977.16968.0365
ENSG00000106211homo_sapiensENSP0000024855376.097663.9024lepisosteus_oculatusENSLOCP0000000341575.362363.285
ENSG00000106211homo_sapiensENSP0000024855372.195160.9756clupea_harengusENSCHAP0000001204166.071455.8036
ENSG00000106211homo_sapiensENSP0000024855364.878152.1951clupea_harengusENSCHAP0000003685365.517252.7094
ENSG00000106211homo_sapiensENSP0000024855370.731759.5122danio_rerioENSDARP0000006016172.864361.3065
ENSG00000106211homo_sapiensENSP0000024855371.219559.5122carassius_auratusENSCARP0000000677169.856558.3732
ENSG00000106211homo_sapiensENSP0000024855368.780557.0732carassius_auratusENSCARP0000010949466.824655.4502
ENSG00000106211homo_sapiensENSP0000024855362.926851.2195astyanax_mexicanusENSAMXP0000003210570.879157.6923
ENSG00000106211homo_sapiensENSP0000024855371.707360.9756astyanax_mexicanusENSAMXP0000004847156.756848.2625
ENSG00000106211homo_sapiensENSP0000024855371.707361.9512ictalurus_punctatusENSIPUP0000001829069.668260.1896
ENSG00000106211homo_sapiensENSP0000024855375.121957.561esox_luciusENSELUP000000208427053.6364
ENSG00000106211homo_sapiensENSP0000024855370.243961.4634electrophorus_electricusENSEEEP0000000013868.246459.7156
ENSG00000106211homo_sapiensENSP0000024855370.731756.0976oncorhynchus_kisutchENSOKIP0000506745659.183746.9388
ENSG00000106211homo_sapiensENSP0000024855371.219557.0732oncorhynchus_kisutchENSOKIP0000502095358.167346.6135
ENSG00000106211homo_sapiensENSP0000024855371.219557.0732oncorhynchus_mykissENSOMYP0000001728057.936546.4286
ENSG00000106211homo_sapiensENSP0000024855373.658559.5122oncorhynchus_mykissENSOMYP0000011667564.529952.1368
ENSG00000106211homo_sapiensENSP0000024855370.731756.5854salmo_salarENSSSAP0000018083258.467746.7742
ENSG00000106211homo_sapiensENSP0000024855371.219556.0976salmo_salarENSSSAP0000012448658.167345.8167
ENSG00000106211homo_sapiensENSP0000024855373.170758.5366salmo_truttaENSSTUP0000005631164.102651.2821
ENSG00000106211homo_sapiensENSP0000024855371.219555.6098salmo_truttaENSSTUP0000003920358.167345.4183
ENSG00000106211homo_sapiensENSP0000024855372.682956.5854gadus_morhuaENSGMOP0000005018768.348653.211
ENSG00000106211homo_sapiensENSP0000024855368.292752.6829fundulus_heteroclitusENSFHEP0000003193769.306953.4653
ENSG00000106211homo_sapiensENSP0000024855367.317151.7073fundulus_heteroclitusENSFHEP0000001644268.316852.4752
ENSG00000106211homo_sapiensENSP0000024855369.756156.0976poecilia_reticulataENSPREP0000001193271.557.5
ENSG00000106211homo_sapiensENSP0000024855369.268354.1463xiphophorus_maculatusENSXMAP0000004081070.29754.9505
ENSG00000106211homo_sapiensENSP0000024855370.731755.122cyclopterus_lumpusENSCLMP0000502567468.720453.5545
ENSG00000106211homo_sapiensENSP0000024855372.195159.0244oreochromis_niloticusENSONIP0000001602672.906459.6059
ENSG00000106211homo_sapiensENSP0000024855371.707358.5366haplochromis_burtoniENSHBUP0000000380972.413859.1133
ENSG00000106211homo_sapiensENSP0000024855371.707358.5366astatotilapia_callipteraENSACLP0000000783372.413859.1133
ENSG00000106211homo_sapiensENSP0000024855373.170758.5366sparus_aurataENSSAUP0001000409071.0956.872
ENSG00000106211homo_sapiensENSP0000024855372.195156.0976lates_calcariferENSLCAP0001003799872.906456.6502
ENSG00000106211homo_sapiensENSP0000024855382.926868.7805xenopus_tropicalisENSXETP0000001965766.929155.5118
ENSG00000106211homo_sapiensENSP0000024855381.463470.2439chrysemys_picta_belliiENSCPBP0000004042577.674466.9767
ENSG00000106211homo_sapiensENSP0000024855381.951270.7317sphenodon_punctatusENSSPUP0000000815277.777867.1296
ENSG00000106211homo_sapiensENSP0000024855382.43970.7317crocodylus_porosusENSCPRP0000500821977.880266.8203
ENSG00000106211homo_sapiensENSP0000024855380.975665.8537laticauda_laticaudataENSLLTP0000001816379.047664.2857
ENSG00000106211homo_sapiensENSP0000024855380.975666.8293notechis_scutatusENSNSUP0000001229679.047665.2381
ENSG00000106211homo_sapiensENSP0000024855381.463467.3171pseudonaja_textilisENSPTXP0000000517879.523865.7143
ENSG00000106211homo_sapiensENSP0000024855356.097644.878anas_platyrhynchos_platyrhynchosENSAPLP0000002984522.243717.795
ENSG00000106211homo_sapiensENSP0000024855372.195159.5122gallus_gallusENSGALP0001004428974.371961.3065
ENSG00000106211homo_sapiensENSP0000024855377.073265.3659meleagris_gallopavoENSMGAP0000000340281.443369.0722
ENSG00000106211homo_sapiensENSP0000024855377.073266.3415serinus_canariaENSSCAP0000000793581.443370.1031
ENSG00000106211homo_sapiensENSP0000024855377.073266.3415parus_majorENSPMJP0000002594981.443370.1031
ENSG00000106211homo_sapiensENSP0000024855371.707358.5366neolamprologus_brichardiENSNBRP0000002113772.413859.1133
ENSG00000106211homo_sapiensENSP0000024855380.975667.8049naja_najaENSNNAP0000002048879.047666.1905
ENSG00000106211homo_sapiensENSP0000024855354.634144.878podarcis_muralisENSPMRP0000002743863.636452.2727
ENSG00000106211homo_sapiensENSP0000024855363.414654.6341geospiza_fortisENSGFOP0000000079379.268368.2927
ENSG00000106211homo_sapiensENSP0000024855376.097667.3171taeniopygia_guttataENSTGUP0000000469181.675472.2513
ENSG00000106211homo_sapiensENSP0000024855375.609864.3902erpetoichthys_calabaricusENSECRP0000002688679.487267.6923
ENSG00000106211homo_sapiensENSP0000024855369.268356.5854kryptolebias_marmoratusENSKMAP0000001809871.356858.2915
ENSG00000106211homo_sapiensENSP0000024855382.43970.2439salvator_merianaeENSSMRP0000000394778.604766.9767
ENSG00000106211homo_sapiensENSP0000024855367.804954.6341oryzias_javanicusENSOJAP0000001298770.558456.8528
ENSG00000106211homo_sapiensENSP0000024855372.195158.0488amphilophus_citrinellusENSACIP0000001603862.447350.211
ENSG00000106211homo_sapiensENSP0000024855373.658559.5122dicentrarchus_labraxENSDLAP0000507693074.384260.0985
ENSG00000106211homo_sapiensENSP0000024855373.170758.0488amphiprion_perculaENSAPEP0000001861753.763442.6523
ENSG00000106211homo_sapiensENSP0000024855368.780555.6098oryzias_sinensisENSOSIP0000004647262.389450.4425
ENSG00000106211homo_sapiensENSP0000024855375.609863.4146pelodiscus_sinensisENSPSIP0000001083571.759360.1852
ENSG00000106211homo_sapiensENSP0000024855380.487868.2927gopherus_evgoodeiENSGEVP0000501858476.744265.1163
ENSG00000106211homo_sapiensENSP0000024855381.463470.2439chelonoidis_abingdoniiENSCABP0000000256377.674466.9767
ENSG00000106211homo_sapiensENSP0000024855372.195158.0488seriola_dumeriliENSSDUP0000002441668.837255.3488
ENSG00000106211homo_sapiensENSP0000024855371.707356.5854cottoperca_gobioENSCGOP0000004201565.919352.0179
ENSG00000106211homo_sapiensENSP0000024855378.048866.8293anser_brachyrhynchusENSABRP0000000167078.817767.4877
ENSG00000106211homo_sapiensENSP0000024855368.292754.6341gasterosteus_aculeatusENSGACP0000002673464.516151.6129
ENSG00000106211homo_sapiensENSP0000024855369.756157.561cynoglossus_semilaevisENSCSEP0000001708967.452855.6604
ENSG00000106211homo_sapiensENSP0000024855369.268355.6098poecilia_formosaENSPFOP000000089387157
ENSG00000106211homo_sapiensENSP0000024855375.121958.5366myripristis_murdjanENSMMDP0000504079274.038557.6923
ENSG00000106211homo_sapiensENSP0000024855371.219557.0732sander_luciopercaENSSLUP0000001168165.765852.7027
ENSG00000106211homo_sapiensENSP0000024855377.073266.8293strigops_habroptilaENSSHBP0000501484681.443370.6186
ENSG00000106211homo_sapiensENSP0000024855372.682958.0488amphiprion_ocellarisENSAOCP0000001710859.647.6
ENSG00000106211homo_sapiensENSP0000024855380.975668.7805terrapene_carolina_triunguisENSTMTP0000002947677.209365.5814
ENSG00000106211homo_sapiensENSP0000024855372.195158.5366hucho_huchoENSHHUP0000006487658.964147.8088
ENSG00000106211homo_sapiensENSP0000024855373.658559.5122hucho_huchoENSHHUP0000001613667.111154.2222
ENSG00000106211homo_sapiensENSP0000024855368.780554.6341betta_splendensENSBSLP0000004371368.780554.6341
ENSG00000106211homo_sapiensENSP0000024855372.682960.9756pygocentrus_nattereriENSPNAP0000000321462.60552.521
ENSG00000106211homo_sapiensENSP0000024855366.341553.1707pygocentrus_nattereriENSPNAP0000002514373.118358.6021
ENSG00000106211homo_sapiensENSP0000024855371.707357.0732anabas_testudineusENSATEP0000000737165.919352.4664
ENSG00000106211homo_sapiensENSP0000024855351.707335.122ciona_savignyiENSCSAVP0000000160354.922337.3057
ENSG00000106211homo_sapiensENSP0000024855371.707357.561seriola_lalandi_dorsalisENSSLDP0000002578170.334956.4593
ENSG00000106211homo_sapiensENSP0000024855371.707358.0488labrus_bergyltaENSLBEP0000000763068.372155.3488
ENSG00000106211homo_sapiensENSP0000024855371.707358.5366pundamilia_nyerereiENSPNYP0000002214656.106945.8015
ENSG00000106211homo_sapiensENSP0000024855371.219557.0732mastacembelus_armatusENSMAMP0000006733170.873856.7961
ENSG00000106211homo_sapiensENSP0000024855371.707359.0244stegastes_partitusENSSPAP0000002354472.772359.901
ENSG00000106211homo_sapiensENSP0000024855371.219557.0732oncorhynchus_tshawytschaENSOTSP0000504552858.167346.6135
ENSG00000106211homo_sapiensENSP0000024855363.902451.7073oncorhynchus_tshawytschaENSOTSP0000508460761.792550
ENSG00000106211homo_sapiensENSP0000024855371.219557.0732acanthochromis_polyacanthusENSAPOP0000000791770.531456.5217
ENSG00000106211homo_sapiensENSP0000024855377.073266.8293aquila_chrysaetos_chrysaetosENSACCP0002000621781.443370.6186
ENSG00000106211homo_sapiensENSP0000024855367.317155.122nothobranchius_furzeriENSNFUP0001502582069.69757.0707
ENSG00000106211homo_sapiensENSP0000024855368.292751.2195cyprinodon_variegatusENSCVAP000000277587052.5
ENSG00000106211homo_sapiensENSP0000024855369.756162.439denticeps_clupeoidesENSDCDP0000001049673.333365.641
ENSG00000106211homo_sapiensENSP0000024855369.756162.439denticeps_clupeoidesENSDCDP0000003685973.333365.641
ENSG00000106211homo_sapiensENSP0000024855369.756154.1463larimichthys_croceaENSLCRP0000503447869.417553.8835
ENSG00000106211homo_sapiensENSP0000024855371.219555.122takifugu_rubripesENSTRUP000000862567356.5
ENSG00000106211homo_sapiensENSP0000024855377.073266.3415ficedula_albicollisENSFALP0000000999281.443370.1031
ENSG00000106211homo_sapiensENSP0000024855370.243955.6098hippocampus_comesENSHCOP0000002295071.641856.7164
ENSG00000106211homo_sapiensENSP0000024855371.707359.0244cyprinus_carpio_carpioENSCCRP0000010606558.333348.0159
ENSG00000106211homo_sapiensENSP0000024855369.756156.5854cyprinus_carpio_carpioENSCCRP000001524606552.7273
ENSG00000106211homo_sapiensENSP0000024855376.585464.8781coturnix_japonicaENSCJPP0000501142380.927868.5567
ENSG00000106211homo_sapiensENSP0000024855369.268355.6098poecilia_latipinnaENSPLAP000000255057157
ENSG00000106211homo_sapiensENSP0000024855370.243958.0488sinocyclocheilus_grahamiENSSGRP0000008790156.692946.8504
ENSG00000106211homo_sapiensENSP0000024855371.219560sinocyclocheilus_grahamiENSSGRP0000008148557.936548.8095
ENSG00000106211homo_sapiensENSP0000024855371.707358.5366maylandia_zebraENSMZEP0000503186072.413859.1133
ENSG00000106211homo_sapiensENSP0000024855371.219556.0976tetraodon_nigroviridisENSTNIP000000113907357.5
ENSG00000106211homo_sapiensENSP0000024855372.682962.9268paramormyrops_kingsleyaeENSPKIP0000004011274.129464.1791
ENSG00000106211homo_sapiensENSP0000024855372.682960.4878paramormyrops_kingsleyaeENSPKIP0000003384271.634659.6154
ENSG00000106211homo_sapiensENSP0000024855358.048846.8293scleropages_formosusENSSFOP0001507817657.211546.1538
ENSG00000106211homo_sapiensENSP0000024855380.975667.8049leptobrachium_leishanenseENSLLEP0000003209176.497764.0553
ENSG00000106211homo_sapiensENSP0000024855373.170757.561scophthalmus_maximusENSSMAP0000000073273.891658.1281

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000502part_of proteasome complex1ISSHomo_sapiens(9606)Component
GO:0001533located_in cornified envelope1IEAHomo_sapiens(9606)Component
GO:0001895involved_in retina homeostasis1HEPHomo_sapiens(9606)Process
GO:0001932involved_in regulation of protein phosphorylation1IMPHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0005080enables protein kinase C binding1ISSHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005615located_in extracellular space1HDAHomo_sapiens(9606)Component
GO:0005634is_active_in nucleus2IBA,IDAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm3IBA,IDA,TASHomo_sapiens(9606)Component
GO:0005819located_in spindle1IEAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0005856located_in cytoskeleton1TASHomo_sapiens(9606)Component
GO:0005925located_in focal adhesion1HDAHomo_sapiens(9606)Component
GO:0006446involved_in regulation of translational initiation1TASHomo_sapiens(9606)Process
GO:0006469involved_in negative regulation of protein kinase activity1ISSHomo_sapiens(9606)Process
GO:0006986involved_in response to unfolded protein1NASHomo_sapiens(9606)Process
GO:0008426enables protein kinase C inhibitor activity1ISSHomo_sapiens(9606)Function
GO:0009408involved_in response to heat1IBAHomo_sapiens(9606)Process
GO:0009615involved_in response to virus1IEPHomo_sapiens(9606)Process
GO:0010506involved_in regulation of autophagy1NASHomo_sapiens(9606)Process
GO:0019901enables protein kinase binding1IPIHomo_sapiens(9606)Function
GO:0030018located_in Z disc1IEAHomo_sapiens(9606)Component
GO:0032731involved_in positive regulation of interleukin-1 beta production1ISSHomo_sapiens(9606)Process
GO:0032760involved_in positive regulation of tumor necrosis factor production1ISSHomo_sapiens(9606)Process
GO:0035556involved_in intracellular signal transduction1IMPHomo_sapiens(9606)Process
GO:0035924involved_in cellular response to vascular endothelial growth factor stimulus1IMPHomo_sapiens(9606)Process
GO:0038033involved_in positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway1IMPHomo_sapiens(9606)Process
GO:0042026involved_in protein refolding1IBAHomo_sapiens(9606)Process
GO:0042802enables identical protein binding2IMP,IPIHomo_sapiens(9606)Function
GO:0042803enables protein homodimerization activity1IDAHomo_sapiens(9606)Function
GO:0043066involved_in negative regulation of apoptotic process2IBA,TASHomo_sapiens(9606)Process
GO:0043122involved_in regulation of I-kappaB kinase/NF-kappaB signaling1ISSHomo_sapiens(9606)Process
GO:0043130enables ubiquitin binding1ISSHomo_sapiens(9606)Function
GO:0043536involved_in positive regulation of blood vessel endothelial cell migration1IMPHomo_sapiens(9606)Process
GO:0044183enables protein folding chaperone1IMPHomo_sapiens(9606)Function
GO:0045766involved_in positive regulation of angiogenesis1IMPHomo_sapiens(9606)Process
GO:0051082enables unfolded protein binding1IBAHomo_sapiens(9606)Function
GO:0061077involved_in chaperone-mediated protein folding1IMPHomo_sapiens(9606)Process
GO:0061629enables RNA polymerase II-specific DNA-binding transcription factor binding1IPIHomo_sapiens(9606)Function
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component
GO:0070527involved_in platelet aggregation1HMPHomo_sapiens(9606)Process
GO:0099641involved_in anterograde axonal protein transport1IMPHomo_sapiens(9606)Process
GO:1902176involved_in negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway1ISSHomo_sapiens(9606)Process
GO:1904115located_in axon cytoplasm1IEAHomo_sapiens(9606)Component
GO:2001028involved_in positive regulation of endothelial cell chemotaxis1IMPHomo_sapiens(9606)Process

Expression