Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerFlavivirusesSARS-COV-2Dengue
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000104738 Gene ID 4173 Accession 6947
Symbol MCM4 Alias NKCD;CDC21;CDC54;IMD54;NKGCD;hCdc21;P1-CDC21 Full Name minichromosome maintenance complex component 4
Status Confidence Length 17976 bases Strand Plus strand
Position 8 : 47960185 - 47978160 RNA binding domain N.A.
Summary The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
MCM4-203 ENST00000518221 572 140aa ENSP00000430329
MCM4-216 ENST00000648407 2598 742aa ENSP00000497881
MCM4-220 ENST00000649838 3157 904aa ENSP00000497648
MCM4-221 ENST00000649919 2957 813aa ENSP00000498202
MCM4-225 ENST00000697120 5442 No protein -
MCM4-201 ENST00000262105 4183 863aa ENSP00000262105
MCM4-226 ENST00000697121 4132 No protein -
MCM4-222 ENST00000649973 4062 863aa ENSP00000496964
MCM4-210 ENST00000520994 522 No protein -
MCM4-217 ENST00000648519 3226 160aa ENSP00000497176
MCM4-214 ENST00000524086 547 81aa ENSP00000427829
MCM4-223 ENST00000650216 2399 749aa ENSP00000497093
MCM4-227 ENST00000697122 1430 394aa ENSP00000513122
MCM4-207 ENST00000519170 734 No protein -
MCM4-206 ENST00000519138 927 No protein -
MCM4-215 ENST00000647877 1256 107aa ENSP00000497251
MCM4-209 ENST00000520637 1981 582aa ENSP00000427875
MCM4-228 ENST00000697123 4041 No protein -
MCM4-208 ENST00000519470 3692 No protein -
MCM4-224 ENST00000650327 235 No protein -
MCM4-205 ENST00000518680 862 No protein -
MCM4-202 ENST00000517709 842 No protein -
MCM4-219 ENST00000648554 755 191aa ENSP00000496985
MCM4-213 ENST00000523853 354 No protein -
MCM4-204 ENST00000518382 366 27aa ENSP00000430864
MCM4-212 ENST00000521261 1342 No protein -
MCM4-211 ENST00000521151 1125 No protein -
MCM4-218 ENST00000648533 733 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000104738homo_sapiensENSP0000047814141.190524.4048homo_sapiensENSP0000049696440.092723.7543
ENSG00000104738homo_sapiensENSP0000048046928.696416.9729homo_sapiensENSP0000049696438.00722.4797
ENSG00000104738homo_sapiensENSP0000041363233.62717.0338homo_sapiensENSP0000049696426.535313.4415
ENSG00000104738homo_sapiensENSP0000030728848.678730.3199homo_sapiensENSP0000049696440.556225.2607
ENSG00000104738homo_sapiensENSP0000026505642.477926.6593homo_sapiensENSP0000049696444.495927.9258
ENSG00000104738homo_sapiensENSP0000021612248.228930.7902homo_sapiensENSP0000049696441.019726.1877
ENSG00000104738homo_sapiensENSP0000047294042.945527.2277homo_sapiensENSP0000049696440.208625.4925
ENSG00000104738homo_sapiensENSP0000026415643.118126.7966homo_sapiensENSP0000049696441.019725.4925

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000104738homo_sapiensENSP0000049696499.652499.3047nomascus_leucogenysENSNLEP0000001618999.652499.3047
ENSG00000104738homo_sapiensENSP0000049696498.261997.7984pan_paniscusENSPPAP0000001691597.583497.1231
ENSG00000104738homo_sapiensENSP0000049696499.768299.4206pongo_abeliiENSPPYP0000004450799.768299.4206
ENSG00000104738homo_sapiensENSP0000049696410099.7682pan_troglodytesENSPTRP0000003464610099.7682
ENSG00000104738homo_sapiensENSP0000049696498.377898.0301gorilla_gorillaENSGGOP0000000595298.606398.2578
ENSG00000104738homo_sapiensENSP0000049696496.176192.4681ornithorhynchus_anatinusENSOANP0000003329690.119486.645
ENSG00000104738homo_sapiensENSP0000049696496.29293.2793sarcophilus_harrisiiENSSHAP0000002049896.180693.1713
ENSG00000104738homo_sapiensENSP0000049696459.212152.6072notamacropus_eugeniiENSMEUP0000000122664.601857.3957
ENSG00000104738homo_sapiensENSP0000049696464.889962.6883choloepus_hoffmanniENSCHOP0000000072797.902194.5804
ENSG00000104738homo_sapiensENSP0000049696495.596892.6999dasypus_novemcinctusENSDNOP0000001108095.375792.4855
ENSG00000104738homo_sapiensENSP0000049696478.67977.2885erinaceus_europaeusENSEEUP0000000763881.905980.4584
ENSG00000104738homo_sapiensENSP0000049696494.090491.0776echinops_telfairiENSETEP0000000145794.418691.3953
ENSG00000104738homo_sapiensENSP0000049696499.420698.4936callithrix_jacchusENSCJAP0000002494389.842989.0052
ENSG00000104738homo_sapiensENSP0000049696499.420699.073cercocebus_atysENSCATP0000001477299.420699.073
ENSG00000104738homo_sapiensENSP0000049696498.841398.4936macaca_fascicularisENSMFAP0000002124099.301598.9523
ENSG00000104738homo_sapiensENSP0000049696499.304798.9571macaca_mulattaENSMMUP0000007729199.304798.9571
ENSG00000104738homo_sapiensENSP0000049696499.420699.073macaca_nemestrinaENSMNEP0000004063599.420699.073
ENSG00000104738homo_sapiensENSP0000049696499.420699.073papio_anubisENSPANP0000001096499.420699.073
ENSG00000104738homo_sapiensENSP0000049696499.420699.073mandrillus_leucophaeusENSMLEP0000001373899.420699.073
ENSG00000104738homo_sapiensENSP0000049696475.086972.0742tursiops_truncatusENSTTRP0000000788093.641689.8844
ENSG00000104738homo_sapiensENSP0000049696496.639693.6269vulpes_vulpesENSVVUP0000002390996.416293.4104
ENSG00000104738homo_sapiensENSP0000049696497.103194.7856mus_spretusMGP_SPRETEiJ_P004235297.215894.8956
ENSG00000104738homo_sapiensENSP0000049696497.682596.292equus_asinusENSEASP0000503824097.682596.292
ENSG00000104738homo_sapiensENSP0000049696493.163488.9919capra_hircusENSCHIP0000001882994.477190.2468
ENSG00000104738homo_sapiensENSP0000049696496.29293.3951loxodonta_africanaENSLAFP0000000965296.403793.5035
ENSG00000104738homo_sapiensENSP0000049696497.450895.7126panthera_leoENSPLOP0000000300197.450895.7126
ENSG00000104738homo_sapiensENSP0000049696497.450896.0603ailuropoda_melanoleucaENSAMEP0000003012297.450896.0603
ENSG00000104738homo_sapiensENSP0000049696493.626990.0348bos_indicus_hybridENSBIXP0000502254896.650792.9426
ENSG00000104738homo_sapiensENSP0000049696498.493697.219oryctolagus_cuniculusENSOCUP0000000146798.379697.1065
ENSG00000104738homo_sapiensENSP0000049696497.914396.4079equus_caballusENSECAP0000001710796.792795.3036
ENSG00000104738homo_sapiensENSP0000049696496.060393.0475canis_lupus_familiarisENSCAFP0084503919090.601187.7596
ENSG00000104738homo_sapiensENSP0000049696497.566695.8285panthera_pardusENSPPRP0000002208897.566695.8285
ENSG00000104738homo_sapiensENSP0000049696498.493697.1031marmota_marmota_marmotaENSMMMP0000002525798.493697.1031
ENSG00000104738homo_sapiensENSP0000049696493.163489.9189balaenoptera_musculusENSBMSP0001002929596.172292.823
ENSG00000104738homo_sapiensENSP0000049696497.798495.4809cavia_porcellusENSCPOP0000000332297.798495.4809
ENSG00000104738homo_sapiensENSP0000049696497.566695.7126felis_catusENSFCAP0000001057397.566695.7126
ENSG00000104738homo_sapiensENSP0000049696497.566696.292ursus_americanusENSUAMP0000002295997.566696.292
ENSG00000104738homo_sapiensENSP0000049696496.29293.6269monodelphis_domesticaENSMODP0000001278696.180693.5185
ENSG00000104738homo_sapiensENSP0000049696430.359227.4623monodelphis_domesticaENSMODP0000005119172.980566.0167
ENSG00000104738homo_sapiensENSP0000049696484.588681.9235bison_bison_bisonENSBBBP0000001072489.790986.9619
ENSG00000104738homo_sapiensENSP0000049696493.279388.876monodon_monocerosENSMMNP0001502426696.291991.7464
ENSG00000104738homo_sapiensENSP0000049696493.974590.1506sus_scrofaENSSSCP0000004767191.950188.2086
ENSG00000104738homo_sapiensENSP0000049696497.450896.1761microcebus_murinusENSMICP0000001425397.450896.1761
ENSG00000104738homo_sapiensENSP0000049696498.030196.4079octodon_degusENSODEP0000000617598.143996.5197
ENSG00000104738homo_sapiensENSP0000049696493.395189.6871ovis_aries_rambouilletENSOARP0002003165693.179289.4798
ENSG00000104738homo_sapiensENSP0000049696497.682596.4079ursus_maritimusENSUMAP0000000855797.682596.4079
ENSG00000104738homo_sapiensENSP0000049696487.137985.9791ochotona_princepsENSOPRP0000000802087.953286.7836
ENSG00000104738homo_sapiensENSP0000049696491.888887.4855delphinapterus_leucasENSDLEP0000002133475.45271.8363
ENSG00000104738homo_sapiensENSP0000049696493.163489.4554physeter_catodonENSPCTP0000501675791.676288.0274
ENSG00000104738homo_sapiensENSP0000049696497.103194.7856mus_caroliMGP_CAROLIEiJ_P004049997.215894.8956
ENSG00000104738homo_sapiensENSP0000049696497.103194.9015mus_musculusENSMUSP0000002335397.215895.0116
ENSG00000104738homo_sapiensENSP0000049696488.296685.3998dipodomys_ordiiENSDORP0000001688193.382490.3186
ENSG00000104738homo_sapiensENSP0000049696498.14696.7555dipodomys_ordiiENSDORP0000000413498.14696.7555
ENSG00000104738homo_sapiensENSP0000049696497.450895.7126mustela_putorius_furoENSMPUP0000000100891.41389.7826
ENSG00000104738homo_sapiensENSP0000049696498.841397.9143aotus_nancymaaeENSANAP0000001710998.498897.5751
ENSG00000104738homo_sapiensENSP0000049696493.742892.6999saimiri_boliviensis_boliviensisENSSBOP0000000816799.50898.401
ENSG00000104738homo_sapiensENSP0000049696449.015145.0753vicugna_pacosENSVPAP0000001121380.725274.2366
ENSG00000104738homo_sapiensENSP0000049696499.304798.9571chlorocebus_sabaeusENSCSAP0000001092799.304798.9571
ENSG00000104738homo_sapiensENSP0000049696488.412586.7903tupaia_belangeriENSTBEP0000000611497.073895.2926
ENSG00000104738homo_sapiensENSP0000049696497.566695.0174mesocricetus_auratusENSMAUP0000002100897.679895.1276
ENSG00000104738homo_sapiensENSP0000049696493.163489.2236phocoena_sinusENSPSNP0000002400396.172292.1053
ENSG00000104738homo_sapiensENSP0000049696490.7387.3696camelus_dromedariusENSCDRP0000502837695.604492.0635
ENSG00000104738homo_sapiensENSP0000049696496.755595.7126carlito_syrichtaENSTSYP0000003422597.09396.0465
ENSG00000104738homo_sapiensENSP0000049696497.21995.5968panthera_tigris_altaicaENSPTIP0000000542197.21995.5968
ENSG00000104738homo_sapiensENSP0000049696480.996578.5631rattus_norvegicusENSRNOP0000009096494.84491.9946
ENSG00000104738homo_sapiensENSP0000049696497.334995.1333rattus_norvegicusENSRNOP0000000251097.447895.2436
ENSG00000104738homo_sapiensENSP0000049696497.566695.4809prolemur_simusENSPSMP0000003601797.566695.4809
ENSG00000104738homo_sapiensENSP0000049696418.771718.4241microtus_ochrogasterENSMOCP0000001930498.181896.3636
ENSG00000104738homo_sapiensENSP0000049696467.439266.5122sorex_araneusENSSARP0000000522387.650686.4458
ENSG00000104738homo_sapiensENSP0000049696497.682595.5968peromyscus_maniculatus_bairdiiENSPEMP0000001758397.795895.7077
ENSG00000104738homo_sapiensENSP0000049696489.571386.7903bos_mutusENSBMUP0000001477997.972194.9303
ENSG00000104738homo_sapiensENSP0000049696496.987394.7856mus_spicilegusENSMSIP0000001907797.099894.8956
ENSG00000104738homo_sapiensENSP0000049696497.450895.365cricetulus_griseus_chok1gshdENSCGRP0000102045797.563895.4756
ENSG00000104738homo_sapiensENSP0000049696481.807680.0695pteropus_vampyrusENSPVAP0000001435481.902580.1624
ENSG00000104738homo_sapiensENSP0000049696496.29294.6698myotis_lucifugusENSMLUP0000000394696.180694.5602
ENSG00000104738homo_sapiensENSP0000049696496.060392.8158vombatus_ursinusENSVURP0001000293095.949192.7083
ENSG00000104738homo_sapiensENSP0000049696496.060392.8158vombatus_ursinusENSVURP0001000648895.949192.7083
ENSG00000104738homo_sapiensENSP0000049696496.871494.9015rhinolophus_ferrumequinumENSRFEP0001001909996.983895.0116
ENSG00000104738homo_sapiensENSP0000049696497.450895.7126neovison_visonENSNVIP0000002592297.450895.7126
ENSG00000104738homo_sapiensENSP0000049696493.626989.9189bos_taurusENSBTAP0000004914996.650792.823
ENSG00000104738homo_sapiensENSP0000049696498.841397.5666heterocephalus_glaber_femaleENSHGLP0000002665798.726997.4537
ENSG00000104738homo_sapiensENSP0000049696499.07398.6095rhinopithecus_bietiENSRBIP0000002781899.07398.6095
ENSG00000104738homo_sapiensENSP0000049696496.871494.2063canis_lupus_dingoENSCAFP0002001930596.871494.2063
ENSG00000104738homo_sapiensENSP0000049696498.609596.9873sciurus_vulgarisENSSVLP0000500855798.609596.9873
ENSG00000104738homo_sapiensENSP0000049696496.523893.2793phascolarctos_cinereusENSPCIP0000003098196.41293.1713
ENSG00000104738homo_sapiensENSP0000049696478.099775.898procavia_capensisENSPCAP0000000098080.815378.5372
ENSG00000104738homo_sapiensENSP0000049696498.377896.9873chinchilla_lanigeraENSCLAP0000002097098.377896.9873
ENSG00000104738homo_sapiensENSP0000049696493.742890.1506cervus_hanglu_yarkandensisENSCHYP0000002960396.770393.0622
ENSG00000104738homo_sapiensENSP0000049696489.918986.3268catagonus_wagneriENSCWAP0000002452297.487493.593
ENSG00000104738homo_sapiensENSP0000049696498.14696.7555ictidomys_tridecemlineatusENSSTOP0000000888998.259996.8678
ENSG00000104738homo_sapiensENSP0000049696498.377897.1031otolemur_garnettiiENSOGAP0000000033097.923996.6551
ENSG00000104738homo_sapiensENSP0000049696499.420698.6095cebus_imitatorENSCCAP0000001354899.420698.6095
ENSG00000104738homo_sapiensENSP0000049696498.261996.9873urocitellus_parryiiENSUPAP0001000411698.719497.4389
ENSG00000104738homo_sapiensENSP0000049696493.51189.9189moschus_moschiferusENSMMSP0000000257296.531192.823
ENSG00000104738homo_sapiensENSP0000049696499.188998.7254rhinopithecus_roxellanaENSRROP0000001641099.188998.7254
ENSG00000104738homo_sapiensENSP0000049696497.334994.9015mus_pahariMGP_PahariEiJ_P002789397.447895.0116
ENSG00000104738homo_sapiensENSP0000049696497.914396.4079propithecus_coquereliENSPCOP0000000680697.914396.4079
ENSG00000104738homo_sapiensENSP0000049696467.55551.4484caenorhabditis_elegansY39G10AR.14a.170.838453.949
ENSG00000104738homo_sapiensENSP0000049696479.258462.92drosophila_melanogasterFBpp031178378.983862.7021
ENSG00000104738homo_sapiensENSP0000049696472.537758.5168ciona_intestinalisENSCINP0000001491679.745264.3312
ENSG00000104738homo_sapiensENSP0000049696480.996567.9027eptatretus_burgeriENSEBUP0000000615282.332269.0224
ENSG00000104738homo_sapiensENSP0000049696488.180880.7648callorhinchus_miliiENSCMIP0000001302687.976980.578
ENSG00000104738homo_sapiensENSP0000049696490.382482.7346latimeria_chalumnaeENSLACP0000001564390.909183.2168
ENSG00000104738homo_sapiensENSP0000049696474.159967.7868lepisosteus_oculatusENSLOCP0000000728394.395386.2832
ENSG00000104738homo_sapiensENSP0000049696489.339580.6489clupea_harengusENSCHAP0000002316289.443280.7425
ENSG00000104738homo_sapiensENSP0000049696488.528480.0695danio_rerioENSDARP0000005856390.414281.7751
ENSG00000104738homo_sapiensENSP0000049696488.644380.1854carassius_auratusENSCARP0000007586087.628979.2669
ENSG00000104738homo_sapiensENSP0000049696487.833179.8378carassius_auratusENSCARP0000007032887.630179.6532
ENSG00000104738homo_sapiensENSP0000049696419.814618.0765carassius_auratusENSCARP0000011570296.067487.6404
ENSG00000104738homo_sapiensENSP0000049696486.326878.4473astyanax_mexicanusENSAMXP0000000440791.41183.0675
ENSG00000104738homo_sapiensENSP0000049696488.412579.2584ictalurus_punctatusENSIPUP0000000014390.295980.9467
ENSG00000104738homo_sapiensENSP0000049696490.034881.8076esox_luciusENSELUP0000004101189.619481.4302
ENSG00000104738homo_sapiensENSP0000049696487.833179.3743electrophorus_electricusENSEEEP0000002243289.386880.7783
ENSG00000104738homo_sapiensENSP0000049696490.266581.8076oncorhynchus_kisutchENSOKIP0000509858489.232580.8706
ENSG00000104738homo_sapiensENSP0000049696490.614181.9235oncorhynchus_kisutchENSOKIP0000503576188.964780.4323
ENSG00000104738homo_sapiensENSP0000049696490.266581.5759oncorhynchus_mykissENSOMYP0000005332588.022679.548
ENSG00000104738homo_sapiensENSP0000049696490.266582.1553oncorhynchus_mykissENSOMYP0000009293486.363678.6031
ENSG00000104738homo_sapiensENSP0000049696490.382481.8076salmo_salarENSSSAP0000009070888.535880.1362
ENSG00000104738homo_sapiensENSP0000049696490.266581.8076salmo_salarENSSSAP0000012109387.331879.148
ENSG00000104738homo_sapiensENSP0000049696490.382481.8076salmo_truttaENSSTUP0000011442788.335279.9547
ENSG00000104738homo_sapiensENSP0000049696490.266581.8076salmo_truttaENSSTUP0000001701987.331879.148
ENSG00000104738homo_sapiensENSP0000049696488.87678.4473gadus_morhuaENSGMOP0000002771488.364177.9954
ENSG00000104738homo_sapiensENSP0000049696489.918981.3441fundulus_heteroclitusENSFHEP0000002847089.400980.8756
ENSG00000104738homo_sapiensENSP0000049696489.571381.9235poecilia_reticulataENSPREP0000001262687.840980.3409
ENSG00000104738homo_sapiensENSP0000049696489.687182.0394xiphophorus_maculatusENSXMAP0000004032989.170581.5668
ENSG00000104738homo_sapiensENSP0000049696486.442679.3743oryzias_latipesENSORLP0000004228089.341382.0359
ENSG00000104738homo_sapiensENSP0000049696488.064979.2584cyclopterus_lumpusENSCLMP0000505019188.167179.3503
ENSG00000104738homo_sapiensENSP0000049696490.498381.9235oreochromis_niloticusENSONIP0000001199490.81482.2093
ENSG00000104738homo_sapiensENSP0000049696490.382481.8076haplochromis_burtoniENSHBUP0000002559190.697782.093
ENSG00000104738homo_sapiensENSP0000049696490.266581.6918astatotilapia_callipteraENSACLP0000002746690.581481.9767
ENSG00000104738homo_sapiensENSP0000049696488.87680.8806sparus_aurataENSSAUP0001001591887.85879.9542
ENSG00000104738homo_sapiensENSP0000049696490.498382.5029lates_calcariferENSLCAP0001001119390.81482.7907
ENSG00000104738homo_sapiensENSP0000049696493.047585.9791xenopus_tropicalisENSXETP0000008983093.047585.9791
ENSG00000104738homo_sapiensENSP0000049696490.150685.0521chrysemys_picta_belliiENSCPBP0000002877495.812890.3941
ENSG00000104738homo_sapiensENSP0000049696490.961884.1251sphenodon_punctatusENSSPUP0000000711891.920485.0117
ENSG00000104738homo_sapiensENSP0000049696493.626987.1379crocodylus_porosusENSCPRP0000502313793.844487.3403
ENSG00000104738homo_sapiensENSP0000049696491.65783.7775laticauda_laticaudataENSLLTP0000000695091.339583.4873
ENSG00000104738homo_sapiensENSP0000049696490.961882.8505notechis_scutatusENSNSUP0000000001991.598683.4306
ENSG00000104738homo_sapiensENSP0000049696483.661675.6663pseudonaja_textilisENSPTXP0000002432889.356480.8168
ENSG00000104738homo_sapiensENSP0000049696487.369679.7219pseudonaja_textilisENSPTXP0000000163492.857184.7291
ENSG00000104738homo_sapiensENSP0000049696493.742887.022anas_platyrhynchos_platyrhynchosENSAPLP0000000299293.960587.2242
ENSG00000104738homo_sapiensENSP0000049696493.163486.3268gallus_gallusENSGALP0001000749593.597286.7288
ENSG00000104738homo_sapiensENSP0000049696488.991982.6188meleagris_gallopavoENSMGAP0000003419590.67384.1795
ENSG00000104738homo_sapiensENSP0000049696483.31475.7822serinus_canariaENSSCAP0000001733088.765480.7407
ENSG00000104738homo_sapiensENSP0000049696493.047586.3268parus_majorENSPMJP0000002113093.372186.6279
ENSG00000104738homo_sapiensENSP0000049696492.699984.7045anolis_carolinensisENSACAP0000003672992.272284.3137
ENSG00000104738homo_sapiensENSP0000049696486.442678.2155neolamprologus_brichardiENSNBRP0000001527592.212683.4363
ENSG00000104738homo_sapiensENSP0000049696491.425383.6616naja_najaENSNNAP0000002598791.319483.5648
ENSG00000104738homo_sapiensENSP0000049696493.047584.7045podarcis_muralisENSPMRP0000000697392.511584.2166
ENSG00000104738homo_sapiensENSP0000049696493.395186.5585geospiza_fortisENSGFOP0000001444693.720986.8605
ENSG00000104738homo_sapiensENSP0000049696489.80382.5029taeniopygia_guttataENSTGUP0000002671987.76980.6342
ENSG00000104738homo_sapiensENSP0000049696491.193583.5458erpetoichthys_calabaricusENSECRP0000001017491.511683.8372
ENSG00000104738homo_sapiensENSP0000049696489.918980.9965kryptolebias_marmoratusENSKMAP0000000692190.127881.1847
ENSG00000104738homo_sapiensENSP0000049696493.163485.6315salvator_merianaeENSSMRP0000001419192.413884.9425
ENSG00000104738homo_sapiensENSP0000049696481.807674.2758oryzias_javanicusENSOJAP0000004475285.060277.2289
ENSG00000104738homo_sapiensENSP0000049696485.863378.3314amphilophus_citrinellusENSACIP0000002374792.27984.1843
ENSG00000104738homo_sapiensENSP0000049696489.80380.7648dicentrarchus_labraxENSDLAP0000506187788.268879.385
ENSG00000104738homo_sapiensENSP0000049696490.266581.8076amphiprion_perculaENSAPEP0000000427890.581482.093
ENSG00000104738homo_sapiensENSP0000049696489.80381.6918oryzias_sinensisENSOSIP0000003303289.80381.6918
ENSG00000104738homo_sapiensENSP0000049696489.918984.3569pelodiscus_sinensisENSPSIP0000001528095.566589.6552
ENSG00000104738homo_sapiensENSP0000049696492.815886.5585pelodiscus_sinensisENSPSIP0000001564995.357188.9286
ENSG00000104738homo_sapiensENSP0000049696415.527214.1367gopherus_evgoodeiENSGEVP0000501724683.7576.25
ENSG00000104738homo_sapiensENSP0000049696495.480989.3395chelonoidis_abingdoniiENSCABP0000000342995.591689.4432
ENSG00000104738homo_sapiensENSP0000049696490.150682.2711seriola_dumeriliENSSDUP0000002494090.3682.4622
ENSG00000104738homo_sapiensENSP0000049696489.918980.533cottoperca_gobioENSCGOP0000000986384.531675.7081
ENSG00000104738homo_sapiensENSP0000049696489.571384.0093struthio_camelus_australisENSSCUP0000001847995.19789.2857
ENSG00000104738homo_sapiensENSP0000049696492.699986.4426anser_brachyrhynchusENSABRP0000001468777.972772.7095
ENSG00000104738homo_sapiensENSP0000049696489.687180.533gasterosteus_aculeatusENSGACP0000002368489.895580.7201
ENSG00000104738homo_sapiensENSP0000049696490.150680.7648cynoglossus_semilaevisENSCSEP0000001607590.570481.1409
ENSG00000104738homo_sapiensENSP0000049696489.571382.1553poecilia_formosaENSPFOP0000001445489.055381.682
ENSG00000104738homo_sapiensENSP0000049696489.571381.6918myripristis_murdjanENSMMDP0000503633886.272378.683
ENSG00000104738homo_sapiensENSP0000049696489.687181.5759sander_luciopercaENSSLUP0000000212188.558380.5492
ENSG00000104738homo_sapiensENSP0000049696489.571381.5759strigops_habroptilaENSSHBP0000500484692.574984.3114
ENSG00000104738homo_sapiensENSP0000049696490.266581.8076amphiprion_ocellarisENSAOCP0000002831190.581482.093
ENSG00000104738homo_sapiensENSP0000049696455.967650.6373terrapene_carolina_triunguisENSTMTP0000001747189.114480.6273
ENSG00000104738homo_sapiensENSP0000049696490.382481.8076hucho_huchoENSHHUP0000001829690.803382.1886
ENSG00000104738homo_sapiensENSP0000049696490.614181.8076hucho_huchoENSHHUP0000000978891.142282.2844
ENSG00000104738homo_sapiensENSP0000049696490.034881.5759betta_splendensENSBSLP0000004636889.310380.9195
ENSG00000104738homo_sapiensENSP0000049696488.528479.8378pygocentrus_nattereriENSPNAP0000002692290.521381.6351
ENSG00000104738homo_sapiensENSP0000049696490.382481.9235anabas_testudineusENSATEP0000004996188.135679.887
ENSG00000104738homo_sapiensENSP0000049696477.056862.8042ciona_savignyiENSCSAVP0000001823875.056461.1738
ENSG00000104738homo_sapiensENSP0000049696464.77444.8436saccharomyces_cerevisiaeYPR019W59.914341.4791
ENSG00000104738homo_sapiensENSP0000049696490.034882.387seriola_lalandi_dorsalisENSSLDP0000001612585.66778.3903
ENSG00000104738homo_sapiensENSP0000049696490.382481.8076pundamilia_nyerereiENSPNYP0000002005290.697782.093
ENSG00000104738homo_sapiensENSP0000049696490.150681.3441mastacembelus_armatusENSMAMP0000004293287.415778.8764
ENSG00000104738homo_sapiensENSP0000049696490.034881.8076stegastes_partitusENSSPAP0000002071290.348882.093
ENSG00000104738homo_sapiensENSP0000049696490.614182.0394oncorhynchus_tshawytschaENSOTSP0000507476288.662180.2721
ENSG00000104738homo_sapiensENSP0000049696490.266581.8076oncorhynchus_tshawytschaENSOTSP0000504166687.923279.684
ENSG00000104738homo_sapiensENSP0000049696490.150681.6918acanthochromis_polyacanthusENSAPOP0000000251390.465181.9767
ENSG00000104738homo_sapiensENSP0000049696494.322187.6014aquila_chrysaetos_chrysaetosENSACCP0002000653694.541287.8049
ENSG00000104738homo_sapiensENSP0000049696490.034881.8076nothobranchius_furzeriENSNFUP0001503363184.456576.7391
ENSG00000104738homo_sapiensENSP0000049696488.644380.8806cyprinodon_variegatusENSCVAP0000002897689.683581.8288
ENSG00000104738homo_sapiensENSP0000049696490.266581.1124larimichthys_croceaENSLCRP0000500106688.926979.9087
ENSG00000104738homo_sapiensENSP0000049696486.558578.0997takifugu_rubripesENSTRUP0000008803285.960977.5604
ENSG00000104738homo_sapiensENSP0000049696493.163486.7903ficedula_albicollisENSFALP0000000601893.379886.9919
ENSG00000104738homo_sapiensENSP0000049696488.87680.0695hippocampus_comesENSHCOP0000002750881.682673.5889
ENSG00000104738homo_sapiensENSP0000049696488.528480.0695cyprinus_carpio_carpioENSCCRP0000015119690.094381.4858
ENSG00000104738homo_sapiensENSP0000049696488.180879.606cyprinus_carpio_carpioENSCCRP0000017049789.214580.5393
ENSG00000104738homo_sapiensENSP0000049696490.498383.6616coturnix_japonicaENSCJPP0000501217890.708583.856
ENSG00000104738homo_sapiensENSP0000049696489.687182.1553poecilia_latipinnaENSPLAP0000000748989.170581.682
ENSG00000104738homo_sapiensENSP0000049696485.979178.4473sinocyclocheilus_grahamiENSSGRP0000002159989.075681.2725
ENSG00000104738homo_sapiensENSP0000049696487.601479.7219sinocyclocheilus_grahamiENSSGRP0000009471588.732480.7512
ENSG00000104738homo_sapiensENSP0000049696490.382481.8076maylandia_zebraENSMZEP0000503354590.697782.093
ENSG00000104738homo_sapiensENSP0000049696489.80381.6918tetraodon_nigroviridisENSTNIP0000001134690.116381.9767
ENSG00000104738homo_sapiensENSP0000049696491.425383.4299paramormyrops_kingsleyaeENSPKIP0000001576891.637683.6237
ENSG00000104738homo_sapiensENSP0000049696490.7382.2711scleropages_formosusENSSFOP0001500780289.078580.7736
ENSG00000104738homo_sapiensENSP0000049696492.120584.5886leptobrachium_leishanenseENSLLEP0000001900392.120584.5886
ENSG00000104738homo_sapiensENSP0000049696490.034881.5759scophthalmus_maximusENSSMAP0000003175288.095279.8186
ENSG00000104738homo_sapiensENSP0000049696488.760180.9965oryzias_melastigmaENSOMEP0000000557685.682378.1879

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000727involved_in double-strand break repair via break-induced replication1IBAHomo_sapiens(9606)Process
GO:0000781located_in chromosome, telomeric region1HDAHomo_sapiens(9606)Component
GO:0003678contributes_to DNA helicase activity1IDAHomo_sapiens(9606)Function
GO:0003697contributes_to single-stranded DNA binding2IDA,ISSHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IEAHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus3IBA,IDA,NASHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0006260involved_in DNA replication1NASHomo_sapiens(9606)Process
GO:0006268involved_in DNA unwinding involved in DNA replication2IBA,IDAHomo_sapiens(9606)Process
GO:0006271involved_in DNA strand elongation involved in DNA replication1IBAHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0016887enables ATP hydrolysis activity1IEAHomo_sapiens(9606)Function
GO:0017116contributes_to single-stranded DNA helicase activity1IBAHomo_sapiens(9606)Function
GO:0030174involved_in regulation of DNA-templated DNA replication initiation1NASHomo_sapiens(9606)Process
GO:0042555part_of MCM complex3IBA,IDA,IPIHomo_sapiens(9606)Component
GO:0071162part_of CMG complex2IPI,ISSHomo_sapiens(9606)Component
GO:1902975involved_in mitotic DNA replication initiation1IBAHomo_sapiens(9606)Process

Expression