RBP Type	Canonical_RBPs
Diseases	CancerSARS-COV-2
Drug	N.A.
Main interacting RNAs	rRNA
Moonlighting functions	N.A.
Localizations	P-bodyNucleoliNucleoli rim
BulkPerturb-seq	DataSet_01_129 DataSet_01_31

Ensembl ID	ENSG00000100029	Gene ID	23481	Accession	8848
Symbol	PES1	Alias	PES;NOP7	Full Name	pescadillo ribosomal biogenesis factor 1
Status	Confidence	Length	30459 bases	Strand	Minus strand
Position	22 : 30576625 - 30607083	RNA binding domain	Pescadillo_N
Summary	This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9. [provided by RefSeq, Aug 2011]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000334612	Pescadillo_N	PF06732	9.9e-123	1
ENSP00000346725	Pescadillo_N	PF06732	1e-122	1
ENSP00000384252	Pescadillo_N	PF06732	1.4e-104	1
ENSP00000384777	Pescadillo_N	PF06732	1.7e-52	1
ENSP00000384366	Pescadillo_N	PF06732	1.7e-51	1
ENSP00000385654	Pescadillo_N	PF06732	1.7e-51	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
31718704	PES1 promotes BET inhibitors resistance and cells proliferation through increasing c-Myc expression in pancreatic cancer.	Xin Jin	2019-11-12	Journal of experimental & clinical cancer research : CR
33634138	Insights Into circRNAs: Functional Roles in Lung Cancer Management and the Potential Mechanisms.	Bing Feng	2021-01-01	Frontiers in cell and developmental biology
32398477	Role of Circular RNAs in Cardiovascular Disease.	Raj Kishore	2020-08-01	Journal of cardiovascular pharmacology
30368217	Circular RNAs as Potential Theranostics in the Cardiovascular System.	Yihua Bei	2018-12-07	Molecular therapy. Nucleic acids
28095716	CircRNAs: a regulator of cellular stress.	W Joseph Fischer	2017-04-01	Critical reviews in biochemistry and molecular biology
34331015	Squaring the circle: circRNAs in melanoma.	Nicol Mecozzi	2021-09-01	Oncogene
35546161	High-throughput analysis of ANRIL circRNA isoforms in human pancreatic islets.	J Hannah MacMillan	2022-05-11	Scientific reports
30159442	Molecular functions and specific roles of circRNAs in the cardiovascular system.	M Lesca Holdt	2018-06-01	Non-coding RNA research
35574355	Circular RNAs and Their Role in Exosomes.	Zeping Han	2022-01-01	Frontiers in oncology
29116363	Molecular roles and function of circular RNAs in eukaryotic cells.	M Lesca Holdt	2018-03-01	Cellular and molecular life sciences : CMLS
27539542	Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans.	M Lesca Holdt	2016-08-19	Nature communications
33644114	Pseudogenes in Cardiovascular Disease.	Yanyan Qi	2020-01-01	Frontiers in molecular biosciences
37498354	circACTA2 inhibits NLRP3 inflammasome-mediated inflammation via interacting with NF-κB in vascular smooth muscle cells.	Yang Bai	2023-07-27	Cellular and molecular life sciences : CMLS
34782005	SNHG17 promotes colorectal tumorigenesis and metastasis via regulating Trim23-PES1 axis and miR-339-5p-FOSL2-SNHG17 positive feedback loop.	Zehua Bian	2021-11-15	Journal of experimental & clinical cancer research : CR
32249490	Systematic characterization of non-coding RNAs in triple-negative breast cancer.	Jie Mei	2020-05-01	Cell proliferation

Name	Transcript ID	bp	Protein	Translation ID
PES1-202	ENST00000354694	2265	588aa	ENSP00000346725
PES1-203	ENST00000402281	2760	449aa	ENSP00000384366
PES1-208	ENST00000441668	999	194aa	ENSP00000404234
PES1-205	ENST00000405677	2708	449aa	ENSP00000385654
PES1-212	ENST00000488719	1732	No protein	-
PES1-204	ENST00000402284	2144	571aa	ENSP00000384252
PES1-201	ENST00000335214	1988	583aa	ENSP00000334612
PES1-206	ENST00000406208	871	135aa	ENSP00000384777
PES1-211	ENST00000477762	513	No protein	-
PES1-207	ENST00000433575	560	No protein	-
PES1-209	ENST00000466614	713	No protein	-
PES1-210	ENST00000467368	490	No protein	-
PES1-213	ENST00000492986	630	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000100029

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000100029	homo_sapiens	ENSP00000346725	90.9864	90.3061	nomascus_leucogenys	ENSNLEP00000004735	92.721	92.0277
ENSG00000100029	homo_sapiens	ENSP00000346725	99.3197	99.1497	pan_paniscus	ENSPPAP00000013110	99.4889	99.3186
ENSG00000100029	homo_sapiens	ENSP00000346725	98.8095	98.4694	pongo_abelii	ENSPPYP00000013069	98.8095	98.4694
ENSG00000100029	homo_sapiens	ENSP00000346725	99.4898	99.3197	pan_troglodytes	ENSPTRP00000024541	99.4898	99.3197
ENSG00000100029	homo_sapiens	ENSP00000346725	99.3197	99.1497	gorilla_gorilla	ENSGGOP00000008344	99.3197	99.1497
ENSG00000100029	homo_sapiens	ENSP00000346725	89.1156	80.7823	ornithorhynchus_anatinus	ENSOANP00000041036	90.5009	82.038
ENSG00000100029	homo_sapiens	ENSP00000346725	87.585	79.932	sarcophilus_harrisii	ENSSHAP00000003322	86.9932	79.3919
ENSG00000100029	homo_sapiens	ENSP00000346725	80.6122	74.3197	notamacropus_eugenii	ENSMEUP00000010634	82.2917	75.8681
ENSG00000100029	homo_sapiens	ENSP00000346725	94.3878	91.4966	dasypus_novemcinctus	ENSDNOP00000012184	95.0342	92.1233
ENSG00000100029	homo_sapiens	ENSP00000346725	61.9048	54.0816	dasypus_novemcinctus	ENSDNOP00000025361	71.6535	62.5984
ENSG00000100029	homo_sapiens	ENSP00000346725	42.8571	41.1565	echinops_telfairi	ENSETEP00000005915	56	53.7778
ENSG00000100029	homo_sapiens	ENSP00000346725	98.1292	97.1088	callithrix_jacchus	ENSCJAP00000081023	98.2964	97.2743
ENSG00000100029	homo_sapiens	ENSP00000346725	99.1497	98.4694	cercocebus_atys	ENSCATP00000027123	98.8136	98.1356
ENSG00000100029	homo_sapiens	ENSP00000346725	75.6803	74.6599	macaca_fascicularis	ENSMFAP00000026653	99.1091	97.7728
ENSG00000100029	homo_sapiens	ENSP00000346725	99.3197	98.6395	macaca_mulatta	ENSMMUP00000023123	99.3197	98.6395
ENSG00000100029	homo_sapiens	ENSP00000346725	95.5782	94.2177	macaca_nemestrina	ENSMNEP00000010225	93.6667	92.3333
ENSG00000100029	homo_sapiens	ENSP00000346725	99.3197	98.6395	papio_anubis	ENSPANP00000013148	99.4889	98.8075
ENSG00000100029	homo_sapiens	ENSP00000346725	99.1497	98.4694	mandrillus_leucophaeus	ENSMLEP00000028804	98.9813	98.3022
ENSG00000100029	homo_sapiens	ENSP00000346725	88.2653	85.8844	tursiops_truncatus	ENSTTRP00000001455	92.6786	90.1786
ENSG00000100029	homo_sapiens	ENSP00000346725	93.5374	89.6258	vulpes_vulpes	ENSVVUP00000003726	94.6644	90.7057
ENSG00000100029	homo_sapiens	ENSP00000346725	92.517	87.9252	vulpes_vulpes	ENSVVUP00000042180	93.9551	89.2919
ENSG00000100029	homo_sapiens	ENSP00000346725	92.3469	88.0952	mus_spretus	MGP_SPRETEiJ_P0026701	92.3469	88.0952
ENSG00000100029	homo_sapiens	ENSP00000346725	94.898	91.4966	equus_asinus	ENSEASP00005061353	93.7815	90.4202
ENSG00000100029	homo_sapiens	ENSP00000346725	92.3469	89.1156	capra_hircus	ENSCHIP00000014971	92.5043	89.2675
ENSG00000100029	homo_sapiens	ENSP00000346725	60.3741	53.9116	loxodonta_africana	ENSLAFP00000017739	75.3716	67.3036
ENSG00000100029	homo_sapiens	ENSP00000346725	95.4082	91.1565	panthera_leo	ENSPLOP00000011067	95.5707	91.3118
ENSG00000100029	homo_sapiens	ENSP00000346725	93.0272	87.9252	ailuropoda_melanoleuca	ENSAMEP00000035281	55.3084	52.275
ENSG00000100029	homo_sapiens	ENSP00000346725	94.0476	90.8163	bos_indicus_hybrid	ENSBIXP00005002061	89.4822	86.4078
ENSG00000100029	homo_sapiens	ENSP00000346725	86.3946	78.9116	oryctolagus_cuniculus	ENSOCUP00000008324	75.5952	69.0476
ENSG00000100029	homo_sapiens	ENSP00000346725	95.9184	92.8571	equus_caballus	ENSECAP00000003465	82.5769	79.9414
ENSG00000100029	homo_sapiens	ENSP00000346725	90.9864	86.5646	canis_lupus_familiaris	ENSCAFP00845028507	86.4297	82.2294
ENSG00000100029	homo_sapiens	ENSP00000346725	95.4082	91.3265	panthera_pardus	ENSPPRP00000001386	95.5707	91.4821
ENSG00000100029	homo_sapiens	ENSP00000346725	94.7279	91.8367	marmota_marmota_marmota	ENSMMMP00000015226	94.5671	91.6808
ENSG00000100029	homo_sapiens	ENSP00000346725	94.3878	92.3469	balaenoptera_musculus	ENSBMSP00010016932	82.5893	80.8036
ENSG00000100029	homo_sapiens	ENSP00000346725	92.1769	89.6258	cavia_porcellus	ENSCPOP00000003221	91.8644	89.322
ENSG00000100029	homo_sapiens	ENSP00000346725	87.585	84.6939	cavia_porcellus	ENSCPOP00000025548	91.4742	88.4547
ENSG00000100029	homo_sapiens	ENSP00000346725	80.6122	75.8503	cavia_porcellus	ENSCPOP00000018039	86.3388	81.2386
ENSG00000100029	homo_sapiens	ENSP00000346725	91.3265	87.415	felis_catus	ENSFCAP00000030001	86.8932	83.1715
ENSG00000100029	homo_sapiens	ENSP00000346725	95.5782	91.6667	ursus_americanus	ENSUAMP00000008002	95.416	91.511
ENSG00000100029	homo_sapiens	ENSP00000346725	87.0748	80.7823	monodelphis_domestica	ENSMODP00000029466	87.5214	81.1966
ENSG00000100029	homo_sapiens	ENSP00000346725	86.2245	83.3333	bison_bison_bison	ENSBBBP00000000683	86.8151	83.9041
ENSG00000100029	homo_sapiens	ENSP00000346725	94.3878	92.0068	monodon_monoceros	ENSMMNP00015008646	81.2591	79.2094
ENSG00000100029	homo_sapiens	ENSP00000346725	93.5374	90.3061	sus_scrofa	ENSSSCP00000010681	92.1273	88.9447
ENSG00000100029	homo_sapiens	ENSP00000346725	95.7483	93.1973	microcebus_murinus	ENSMICP00000009222	95.9114	93.356
ENSG00000100029	homo_sapiens	ENSP00000346725	91.4966	88.4354	octodon_degus	ENSODEP00000004180	91.1864	88.1356
ENSG00000100029	homo_sapiens	ENSP00000346725	72.7891	67.517	jaculus_jaculus	ENSJJAP00000005789	89.916	83.4034
ENSG00000100029	homo_sapiens	ENSP00000346725	95.4082	91.4966	jaculus_jaculus	ENSJJAP00000001595	95.7338	91.8089
ENSG00000100029	homo_sapiens	ENSP00000346725	93.5374	89.7959	ovis_aries_rambouillet	ENSOARP00020020643	94.0171	90.2564
ENSG00000100029	homo_sapiens	ENSP00000346725	95.2381	91.3265	ursus_maritimus	ENSUMAP00000022463	93.6455	89.7993
ENSG00000100029	homo_sapiens	ENSP00000346725	94.5578	89.6258	ochotona_princeps	ENSOPRP00000000582	93.7605	88.8702
ENSG00000100029	homo_sapiens	ENSP00000346725	92.6871	89.2857	delphinapterus_leucas	ENSDLEP00000023802	92.3729	88.983
ENSG00000100029	homo_sapiens	ENSP00000346725	94.5578	92.0068	physeter_catodon	ENSPCTP00005007102	94.7189	92.1635
ENSG00000100029	homo_sapiens	ENSP00000346725	87.7551	83.8435	mus_caroli	MGP_CAROLIEiJ_P0025376	92.8058	88.6691
ENSG00000100029	homo_sapiens	ENSP00000346725	92.6871	88.0952	mus_musculus	ENSMUSP00000105612	92.6871	88.0952
ENSG00000100029	homo_sapiens	ENSP00000346725	90.9864	85.7143	dipodomys_ordii	ENSDORP00000015651	89.0183	83.8602
ENSG00000100029	homo_sapiens	ENSP00000346725	95.4082	91.6667	mustela_putorius_furo	ENSMPUP00000012850	95.5707	91.8228
ENSG00000100029	homo_sapiens	ENSP00000346725	98.2993	97.449	aotus_nancymaae	ENSANAP00000037941	98.2993	97.449
ENSG00000100029	homo_sapiens	ENSP00000346725	97.619	96.4286	saimiri_boliviensis_boliviensis	ENSSBOP00000019033	97.7853	96.5928
ENSG00000100029	homo_sapiens	ENSP00000346725	99.3197	98.4694	chlorocebus_sabaeus	ENSCSAP00000005457	99.1511	98.3022
ENSG00000100029	homo_sapiens	ENSP00000346725	94.3878	90.9864	tupaia_belangeri	ENSTBEP00000008509	95.3608	91.9244
ENSG00000100029	homo_sapiens	ENSP00000346725	92.517	86.9048	mesocricetus_auratus	ENSMAUP00000020435	92.0474	86.4636
ENSG00000100029	homo_sapiens	ENSP00000346725	94.7279	92.517	phocoena_sinus	ENSPSNP00000008645	95.0512	92.8328
ENSG00000100029	homo_sapiens	ENSP00000346725	93.7075	91.4966	camelus_dromedarius	ENSCDRP00005019727	93.5484	91.3413
ENSG00000100029	homo_sapiens	ENSP00000346725	96.2585	93.3673	carlito_syrichta	ENSTSYP00000008999	96.4225	93.5264
ENSG00000100029	homo_sapiens	ENSP00000346725	71.4286	67.8571	panthera_tigris_altaica	ENSPTIP00000026141	93.75	89.0625
ENSG00000100029	homo_sapiens	ENSP00000346725	93.3673	89.6258	rattus_norvegicus	ENSRNOP00000005996	93.686	89.9317
ENSG00000100029	homo_sapiens	ENSP00000346725	96.0884	93.8775	prolemur_simus	ENSPSMP00000024743	96.0884	93.8775
ENSG00000100029	homo_sapiens	ENSP00000346725	93.5374	89.966	microtus_ochrogaster	ENSMOCP00000026048	93.5374	89.966
ENSG00000100029	homo_sapiens	ENSP00000346725	94.5578	89.4558	peromyscus_maniculatus_bairdii	ENSPEMP00000012206	93.4454	88.4034
ENSG00000100029	homo_sapiens	ENSP00000346725	83.5034	79.7619	bos_mutus	ENSBMUP00000011592	91.6045	87.5
ENSG00000100029	homo_sapiens	ENSP00000346725	92.517	88.4354	mus_spicilegus	ENSMSIP00000003015	92.9915	88.8889
ENSG00000100029	homo_sapiens	ENSP00000346725	87.585	80.4422	vombatus_ursinus	ENSVURP00010014390	89.1003	81.8339
ENSG00000100029	homo_sapiens	ENSP00000346725	95.5782	93.3673	rhinolophus_ferrumequinum	ENSRFEP00010012084	95.9044	93.686
ENSG00000100029	homo_sapiens	ENSP00000346725	95.2381	91.4966	neovison_vison	ENSNVIP00000002294	95.4003	91.6525
ENSG00000100029	homo_sapiens	ENSP00000346725	94.0476	90.8163	bos_taurus	ENSBTAP00000010163	89.4822	86.4078
ENSG00000100029	homo_sapiens	ENSP00000346725	94.2177	90.4762	heterocephalus_glaber_female	ENSHGLP00000025952	90.5229	86.9281
ENSG00000100029	homo_sapiens	ENSP00000346725	94.898	93.7075	rhinopithecus_bieti	ENSRBIP00000033821	93.311	92.1405
ENSG00000100029	homo_sapiens	ENSP00000346725	94.0476	90.3061	canis_lupus_dingo	ENSCAFP00020001059	94.6918	90.9247
ENSG00000100029	homo_sapiens	ENSP00000346725	95.068	92.1769	sciurus_vulgaris	ENSSVLP00005010905	94.4257	91.5541
ENSG00000100029	homo_sapiens	ENSP00000346725	87.7551	80.6122	phascolarctos_cinereus	ENSPCIP00000032319	88.0546	80.8874
ENSG00000100029	homo_sapiens	ENSP00000346725	71.2585	68.7075	procavia_capensis	ENSPCAP00000010800	71.2585	68.7075
ENSG00000100029	homo_sapiens	ENSP00000346725	94.2177	91.3265	nannospalax_galili	ENSNGAP00000013833	94.5392	91.6382
ENSG00000100029	homo_sapiens	ENSP00000346725	93.7075	90.1361	bos_grunniens	ENSBGRP00000039012	86.9085	83.5962
ENSG00000100029	homo_sapiens	ENSP00000346725	93.8775	91.4966	chinchilla_lanigera	ENSCLAP00000015683	94.6827	92.2813
ENSG00000100029	homo_sapiens	ENSP00000346725	94.5578	92.3469	cervus_hanglu_yarkandensis	ENSCHYP00000004718	92.2056	90.0498
ENSG00000100029	homo_sapiens	ENSP00000346725	93.5374	90.8163	catagonus_wagneri	ENSCWAP00000015169	94.6644	91.9105
ENSG00000100029	homo_sapiens	ENSP00000346725	94.0476	91.1565	ictidomys_tridecemlineatus	ENSSTOP00000012493	94.5299	91.6239
ENSG00000100029	homo_sapiens	ENSP00000346725	94.0476	90.3061	otolemur_garnettii	ENSOGAP00000005194	94.3686	90.6143
ENSG00000100029	homo_sapiens	ENSP00000346725	97.619	96.0884	cebus_imitator	ENSCCAP00000017387	97.619	96.0884
ENSG00000100029	homo_sapiens	ENSP00000346725	94.3878	91.3265	urocitellus_parryii	ENSUPAP00010026835	93.75	90.7095
ENSG00000100029	homo_sapiens	ENSP00000346725	92.6871	89.966	moschus_moschiferus	ENSMMSP00000033057	83.9753	81.51
ENSG00000100029	homo_sapiens	ENSP00000346725	98.6395	97.9592	rhinopithecus_roxellana	ENSRROP00000008695	98.9761	98.2935
ENSG00000100029	homo_sapiens	ENSP00000346725	84.6939	81.2925	mus_pahari	MGP_PahariEiJ_P0030572	77.8125	74.6875
ENSG00000100029	homo_sapiens	ENSP00000346725	95.9184	93.5374	propithecus_coquereli	ENSPCOP00000009664	95.9184	93.5374
ENSG00000100029	homo_sapiens	ENSP00000346725	55.102	39.4558	caenorhabditis_elegans	R13A5.12.1	61.0169	43.6912
ENSG00000100029	homo_sapiens	ENSP00000346725	61.0544	43.8776	drosophila_melanogaster	FBpp0079445	57.2568	41.1483
ENSG00000100029	homo_sapiens	ENSP00000346725	34.6939	27.381	petromyzon_marinus	ENSPMAP00000008293	65.3846	51.6026
ENSG00000100029	homo_sapiens	ENSP00000346725	58.5034	44.898	eptatretus_burgeri	ENSEBUP00000016303	66.4093	50.9653
ENSG00000100029	homo_sapiens	ENSP00000346725	83.1633	71.5986	callorhinchus_milii	ENSCMIP00000015148	84.3103	72.5862
ENSG00000100029	homo_sapiens	ENSP00000346725	83.8435	73.9796	latimeria_chalumnae	ENSLACP00000019460	84.4178	74.4863
ENSG00000100029	homo_sapiens	ENSP00000346725	73.9796	64.7959	lepisosteus_oculatus	ENSLOCP00000004713	80.5556	70.5556
ENSG00000100029	homo_sapiens	ENSP00000346725	81.4626	70.5782	clupea_harengus	ENSCHAP00000006597	82.3024	71.3058
ENSG00000100029	homo_sapiens	ENSP00000346725	82.483	72.7891	danio_rerio	ENSDARP00000026992	83.1904	73.4134
ENSG00000100029	homo_sapiens	ENSP00000346725	78.0612	68.0272	carassius_auratus	ENSCARP00000126283	78.7307	68.6106
ENSG00000100029	homo_sapiens	ENSP00000346725	73.6395	63.2653	astyanax_mexicanus	ENSAMXP00000001242	79.304	68.1319
ENSG00000100029	homo_sapiens	ENSP00000346725	82.9932	70.5782	ictalurus_punctatus	ENSIPUP00000030001	83.9931	71.4286
ENSG00000100029	homo_sapiens	ENSP00000346725	82.3129	71.5986	esox_lucius	ENSELUP00000001862	82.3129	71.5986
ENSG00000100029	homo_sapiens	ENSP00000346725	80.4422	69.898	electrophorus_electricus	ENSEEEP00000017970	82.8371	71.979
ENSG00000100029	homo_sapiens	ENSP00000346725	78.7415	69.3878	oncorhynchus_kisutch	ENSOKIP00005109032	78.0776	68.8027
ENSG00000100029	homo_sapiens	ENSP00000346725	74.8299	65.3061	oncorhynchus_kisutch	ENSOKIP00005013424	77.7385	67.8445
ENSG00000100029	homo_sapiens	ENSP00000346725	75.1701	66.4966	oncorhynchus_mykiss	ENSOMYP00000005741	79.0698	69.9463
ENSG00000100029	homo_sapiens	ENSP00000346725	81.1225	71.5986	oncorhynchus_mykiss	ENSOMYP00000028632	81.1225	71.5986
ENSG00000100029	homo_sapiens	ENSP00000346725	81.2925	71.4286	salmo_salar	ENSSSAP00000123958	81.8493	71.9178
ENSG00000100029	homo_sapiens	ENSP00000346725	80.6122	70.9184	salmo_salar	ENSSSAP00000112919	81.3036	71.5266
ENSG00000100029	homo_sapiens	ENSP00000346725	80.9524	71.2585	salmo_trutta	ENSSTUP00000029793	81.2287	71.5017
ENSG00000100029	homo_sapiens	ENSP00000346725	80.9524	71.4286	salmo_trutta	ENSSTUP00000065967	81.3675	71.7949
ENSG00000100029	homo_sapiens	ENSP00000346725	80.9524	69.898	gadus_morhua	ENSGMOP00000013914	81.6467	70.4974
ENSG00000100029	homo_sapiens	ENSP00000346725	77.0408	66.6667	fundulus_heteroclitus	ENSFHEP00000011494	84.2007	72.8625
ENSG00000100029	homo_sapiens	ENSP00000346725	79.0816	68.8775	poecilia_reticulata	ENSPREP00000033339	84.854	73.9051
ENSG00000100029	homo_sapiens	ENSP00000346725	79.5918	69.7279	xiphophorus_maculatus	ENSXMAP00000007738	84.6293	74.1411
ENSG00000100029	homo_sapiens	ENSP00000346725	80.7823	69.0476	oryzias_latipes	ENSORLP00000031409	79.5645	68.0067
ENSG00000100029	homo_sapiens	ENSP00000346725	76.8708	65.1361	cyclopterus_lumpus	ENSCLMP00005016170	81.295	68.8849
ENSG00000100029	homo_sapiens	ENSP00000346725	82.6531	72.2789	oreochromis_niloticus	ENSONIP00000050119	82.9352	72.5256
ENSG00000100029	homo_sapiens	ENSP00000346725	64.2857	53.9116	haplochromis_burtoni	ENSHBUP00000006552	79.9154	67.019
ENSG00000100029	homo_sapiens	ENSP00000346725	82.6531	71.0884	astatotilapia_calliptera	ENSACLP00000001173	84.965	73.0769
ENSG00000100029	homo_sapiens	ENSP00000346725	80.102	69.0476	sparus_aurata	ENSSAUP00010059461	81.913	70.6087
ENSG00000100029	homo_sapiens	ENSP00000346725	82.483	71.4286	lates_calcarifer	ENSLCAP00010060603	82.7645	71.6724
ENSG00000100029	homo_sapiens	ENSP00000346725	84.3537	71.0884	xenopus_tropicalis	ENSXETP00000077461	84.9315	71.5753
ENSG00000100029	homo_sapiens	ENSP00000346725	86.3946	78.2313	chrysemys_picta_bellii	ENSCPBP00000009788	87.5862	79.3103
ENSG00000100029	homo_sapiens	ENSP00000346725	85.7143	77.0408	sphenodon_punctatus	ENSSPUP00000023675	87.3484	78.5095
ENSG00000100029	homo_sapiens	ENSP00000346725	85.8844	77.0408	crocodylus_porosus	ENSCPRP00005009047	86.7698	77.8351
ENSG00000100029	homo_sapiens	ENSP00000346725	85.3742	76.8708	laticauda_laticaudata	ENSLLTP00000024447	85.2292	76.7402
ENSG00000100029	homo_sapiens	ENSP00000346725	85.3742	77.2109	notechis_scutatus	ENSNSUP00000006127	85.3742	77.2109
ENSG00000100029	homo_sapiens	ENSP00000346725	85.3742	77.0408	pseudonaja_textilis	ENSPTXP00000024657	85.2292	76.91
ENSG00000100029	homo_sapiens	ENSP00000346725	64.2857	55.4422	anas_platyrhynchos_platyrhynchos	ENSAPLP00000018892	80.2548	69.2144
ENSG00000100029	homo_sapiens	ENSP00000346725	81.8027	73.8095	meleagris_gallopavo	ENSMGAP00000015264	84.6831	76.4084
ENSG00000100029	homo_sapiens	ENSP00000346725	80.2721	70.068	serinus_canaria	ENSSCAP00000001459	82.9525	72.4077
ENSG00000100029	homo_sapiens	ENSP00000346725	69.3878	62.0748	parus_major	ENSPMJP00000026105	58.6207	52.4425
ENSG00000100029	homo_sapiens	ENSP00000346725	81.6327	72.9592	anolis_carolinensis	ENSACAP00000022028	85.1064	76.0638
ENSG00000100029	homo_sapiens	ENSP00000346725	82.3129	71.0884	neolamprologus_brichardi	ENSNBRP00000008124	84.6154	73.0769
ENSG00000100029	homo_sapiens	ENSP00000346725	81.1225	72.619	naja_naja	ENSNNAP00000025787	87.3626	78.2051
ENSG00000100029	homo_sapiens	ENSP00000346725	53.9116	46.4286	podarcis_muralis	ENSPMRP00000036846	75.8373	65.311
ENSG00000100029	homo_sapiens	ENSP00000346725	80.9524	71.5986	geospiza_fortis	ENSGFOP00000007977	85.7658	75.8559
ENSG00000100029	homo_sapiens	ENSP00000346725	85.5442	77.2109	taeniopygia_guttata	ENSTGUP00000015894	86.4261	78.0069
ENSG00000100029	homo_sapiens	ENSP00000346725	75.1701	62.415	erpetoichthys_calabaricus	ENSECRP00000031919	78.3688	65.0709
ENSG00000100029	homo_sapiens	ENSP00000346725	81.9728	71.5986	kryptolebias_marmoratus	ENSKMAP00000020603	82.9604	72.4613
ENSG00000100029	homo_sapiens	ENSP00000346725	86.7347	76.7007	salvator_merianae	ENSSMRP00000023331	82.391	72.8595
ENSG00000100029	homo_sapiens	ENSP00000346725	81.9728	70.068	oryzias_javanicus	ENSOJAP00000040126	82.8179	70.7904
ENSG00000100029	homo_sapiens	ENSP00000346725	81.4626	71.0884	amphilophus_citrinellus	ENSACIP00000022646	83.7413	73.0769
ENSG00000100029	homo_sapiens	ENSP00000346725	82.6531	70.4082	dicentrarchus_labrax	ENSDLAP00005036531	83.2192	70.8904
ENSG00000100029	homo_sapiens	ENSP00000346725	82.6531	70.7483	amphiprion_percula	ENSAPEP00000031966	82.9352	70.9898
ENSG00000100029	homo_sapiens	ENSP00000346725	82.1429	69.7279	oryzias_sinensis	ENSOSIP00000040500	82.8473	70.3259
ENSG00000100029	homo_sapiens	ENSP00000346725	85.8844	78.7415	gopherus_evgoodei	ENSGEVP00005026099	76.9817	70.5793
ENSG00000100029	homo_sapiens	ENSP00000346725	87.0748	78.4014	chelonoidis_abingdonii	ENSCABP00000004813	88.2759	79.4828
ENSG00000100029	homo_sapiens	ENSP00000346725	82.9932	71.2585	seriola_dumerili	ENSSDUP00000018149	82.9932	71.2585
ENSG00000100029	homo_sapiens	ENSP00000346725	81.6327	70.068	cottoperca_gobio	ENSCGOP00000040172	82.7586	71.0345
ENSG00000100029	homo_sapiens	ENSP00000346725	60.3741	48.1293	struthio_camelus_australis	ENSSCUP00000024890	67.3624	53.7002
ENSG00000100029	homo_sapiens	ENSP00000346725	85.8844	76.3605	anser_brachyrhynchus	ENSABRP00000022430	86.7698	77.1478
ENSG00000100029	homo_sapiens	ENSP00000346725	80.9524	68.8775	gasterosteus_aculeatus	ENSGACP00000012290	81.9277	69.7074
ENSG00000100029	homo_sapiens	ENSP00000346725	81.6327	70.068	cynoglossus_semilaevis	ENSCSEP00000027577	81.6327	70.068
ENSG00000100029	homo_sapiens	ENSP00000346725	82.1429	70.4082	poecilia_formosa	ENSPFOP00000014914	83.4197	71.5026
ENSG00000100029	homo_sapiens	ENSP00000346725	81.8027	71.5986	myripristis_murdjan	ENSMMDP00005028603	82.2222	71.9658
ENSG00000100029	homo_sapiens	ENSP00000346725	83.1633	71.9388	sander_lucioperca	ENSSLUP00000058439	83.8765	72.5557
ENSG00000100029	homo_sapiens	ENSP00000346725	86.7347	76.7007	strigops_habroptila	ENSSHBP00005006120	87.0307	76.9625
ENSG00000100029	homo_sapiens	ENSP00000346725	82.483	70.4082	amphiprion_ocellaris	ENSAOCP00000005336	82.6235	70.5281
ENSG00000100029	homo_sapiens	ENSP00000346725	86.5646	78.9116	terrapene_carolina_triunguis	ENSTMTP00000005937	87.7586	80
ENSG00000100029	homo_sapiens	ENSP00000346725	81.9728	71.5986	hucho_hucho	ENSHHUP00000072417	82.1124	71.7206
ENSG00000100029	homo_sapiens	ENSP00000346725	81.4626	70.9184	hucho_hucho	ENSHHUP00000034441	82.0205	71.4041
ENSG00000100029	homo_sapiens	ENSP00000346725	82.6531	69.7279	pygocentrus_nattereri	ENSPNAP00000032671	83.5052	70.4467
ENSG00000100029	homo_sapiens	ENSP00000346725	81.9728	70.2381	anabas_testudineus	ENSATEP00000063157	82.3932	70.5983
ENSG00000100029	homo_sapiens	ENSP00000346725	58.3333	38.7755	saccharomyces_cerevisiae	YGR103W	56.6942	37.686
ENSG00000100029	homo_sapiens	ENSP00000346725	82.3129	71.0884	seriola_lalandi_dorsalis	ENSSLDP00000033136	82.5939	71.3311
ENSG00000100029	homo_sapiens	ENSP00000346725	78.5714	67.0068	labrus_bergylta	ENSLBEP00000015968	81.338	69.3662
ENSG00000100029	homo_sapiens	ENSP00000346725	81.2925	70.2381	mastacembelus_armatus	ENSMAMP00000021852	82.1306	70.9622
ENSG00000100029	homo_sapiens	ENSP00000346725	82.3129	70.7483	stegastes_partitus	ENSSPAP00000025104	82.4531	70.8688
ENSG00000100029	homo_sapiens	ENSP00000346725	72.1088	62.9252	oncorhynchus_tshawytscha	ENSOTSP00005033681	76.951	67.1506
ENSG00000100029	homo_sapiens	ENSP00000346725	72.1088	62.9252	oncorhynchus_tshawytscha	ENSOTSP00005063557	76.951	67.1506
ENSG00000100029	homo_sapiens	ENSP00000346725	78.9116	70.068	oncorhynchus_tshawytscha	ENSOTSP00005101016	76.9486	68.325
ENSG00000100029	homo_sapiens	ENSP00000346725	83.1633	71.9388	acanthochromis_polyacanthus	ENSAPOP00000007961	83.4471	72.1843
ENSG00000100029	homo_sapiens	ENSP00000346725	84.3537	74.8299	aquila_chrysaetos_chrysaetos	ENSACCP00020003726	86.4111	76.6551
ENSG00000100029	homo_sapiens	ENSP00000346725	81.2925	69.3878	nothobranchius_furzeri	ENSNFUP00015051499	82.4138	70.3448
ENSG00000100029	homo_sapiens	ENSP00000346725	82.3129	70.5782	cyprinodon_variegatus	ENSCVAP00000026194	83.4483	71.5517
ENSG00000100029	homo_sapiens	ENSP00000346725	81.9728	70.068	denticeps_clupeoides	ENSDCDP00000028547	82.9604	70.9122
ENSG00000100029	homo_sapiens	ENSP00000346725	82.6531	71.5986	larimichthys_crocea	ENSLCRP00005013463	83.0769	71.9658
ENSG00000100029	homo_sapiens	ENSP00000346725	81.9728	69.2177	takifugu_rubripes	ENSTRUP00000040679	82.9604	70.0516
ENSG00000100029	homo_sapiens	ENSP00000346725	35.2041	27.381	ficedula_albicollis	ENSFALP00000019926	57.5	44.7222
ENSG00000100029	homo_sapiens	ENSP00000346725	76.0204	63.9456	hippocampus_comes	ENSHCOP00000013455	76.0204	63.9456
ENSG00000100029	homo_sapiens	ENSP00000346725	81.1225	71.7687	cyprinus_carpio_carpio	ENSCCRP00000121805	81.9588	72.5086
ENSG00000100029	homo_sapiens	ENSP00000346725	78.5714	70.4082	coturnix_japonica	ENSCJPP00005018209	87.666	78.5579
ENSG00000100029	homo_sapiens	ENSP00000346725	82.1429	70.5782	poecilia_latipinna	ENSPLAP00000002519	83.4197	71.6753
ENSG00000100029	homo_sapiens	ENSP00000346725	78.9116	70.068	sinocyclocheilus_grahami	ENSSGRP00000087402	80.4159	71.4038
ENSG00000100029	homo_sapiens	ENSP00000346725	65.6463	57.3129	sinocyclocheilus_grahami	ENSSGRP00000076966	77.9798	68.0808
ENSG00000100029	homo_sapiens	ENSP00000346725	67.517	56.6327	tetraodon_nigroviridis	ENSTNIP00000018983	76.938	64.5349
ENSG00000100029	homo_sapiens	ENSP00000346725	80.7823	69.898	paramormyrops_kingsleyae	ENSPKIP00000009785	79.1667	68.5
ENSG00000100029	homo_sapiens	ENSP00000346725	80.2721	66.8367	scleropages_formosus	ENSSFOP00015075475	80.8219	67.2945
ENSG00000100029	homo_sapiens	ENSP00000346725	81.4626	68.8775	leptobrachium_leishanense	ENSLLEP00000023078	82.3024	69.5876
ENSG00000100029	homo_sapiens	ENSP00000346725	82.6531	70.9184	scophthalmus_maximus	ENSSMAP00000019767	83.0769	71.2821
ENSG00000100029	homo_sapiens	ENSP00000346725	81.4626	70.068	oryzias_melastigma	ENSOMEP00000023032	82.3024	70.7904

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000463	involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2	IBA,IMP	Homo_sapiens(9606)	Process
GO:0000466	involved_in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1	IMP	Homo_sapiens(9606)	Process
GO:0003723	enables RNA binding	2	HDA,IBA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005654	located_in nucleoplasm	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0005694	located_in chromosome	1	IDA	Homo_sapiens(9606)	Component
GO:0005730	located_in nucleolus	1	IDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	IDA	Homo_sapiens(9606)	Component
GO:0006364	acts_upstream_of_or_within rRNA processing	1	IMP	Homo_sapiens(9606)	Process
GO:0008283	acts_upstream_of_or_within cell population proliferation	1	IMP	Homo_sapiens(9606)	Process
GO:0016020	located_in membrane	1	HDA	Homo_sapiens(9606)	Component
GO:0030687	part_of preribosome, large subunit precursor	1	IDA	Homo_sapiens(9606)	Component
GO:0042273	involved_in ribosomal large subunit biogenesis	1	IC	Homo_sapiens(9606)	Process
GO:0043021	enables ribonucleoprotein complex binding	1	IEA	Homo_sapiens(9606)	Function
GO:0051726	involved_in regulation of cell cycle	1	IMP	Homo_sapiens(9606)	Process
GO:0070545	part_of PeBoW complex	2	IBA,IDA	Homo_sapiens(9606)	Component