Ensembl ID ENSG00000100029 Gene ID 23481 Accession 8848
Gene Symbol PES1 Alias PES;NOP7 Full Name pescadillo ribosomal biogenesis factor 1
Position 22 : 30576625 - 30607083 Length 30459 bases Strand Minus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9. [provided by RefSeq, Aug 2011]

ENSG00000100029 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000100029 PES1 0.50 5.02e-21 KIRC
ENSG00000100029 PES1 0.53 4.84e-16 BRCA
ENSG00000100029 PES1 0.84 5.08e-19 COAD
ENSG00000100029 PES1 1.18 1.16e-40 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000100029 PES1 cancer 22304779
ENSG00000100029 PES1 breast cancer 22820289
ENSG00000100029 PES1 breast cancer 22820293
ENSG00000100029 PES1 Colon Cancer 22860098
ENSG00000100029 PES1 colorectal cancer 23333390
ENSG00000100029 PES1 ovarian cancer 24376209
ENSG00000100029 PES1 tumor 25557119
ENSG00000100029 PES1 gastric cancer 26423399
ENSG00000100029 PES1 tumor 27409667
ENSG00000100029 PES1 tumor 28143451
ENSG00000100029 PES1 gastric cancer 30172011
ENSG00000100029 PES1 tumor 30705367
ENSG00000100029 PES1 cancers 31106266
ENSG00000100029 PES1 liver cancer 31127852
ENSG00000100029 PES1 pancreatic cancer 31718704
ENSG00000100029 PES1 Liver Cancer 31814761
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000100029 PES1 SARC 0.019 high
ENSG00000100029 PES1 STAD 0.0015 low
ENSG00000100029 PES1 PAAD 0.042 high
ENSG00000100029 PES1 UCEC 0.028 high
ENSG00000100029 PES1 THCA 0.045 low
ENSG00000100029 PES1 ACC 0.00061 high
ENSG00000100029 PES1 LUSC 0.022 low
ENSG00000100029 PES1 HNSC 0.003 high
ENSG00000100029 PES1 READ 0.00018 low
ENSG00000100029 PES1 KIRP 0.04 low
ENSG00000100029 PES1 KICH 0.0054 high
ENSG00000100029 PES1 LUAD 0.00079 high
ENSG00000100029 PES1 PCPG 0.014 low
ENSG00000100029 PES1 COAD 0.027 high
ENSG00000100029 PES1 DLBC 0.015 low
ENSG00000100029 PES1 KIRC 0.012 low
ENSG00000100029 PES1 PRAD 0.0082 high
ENSG00000100029 PES1 BLCA 0.02 high
ENSG00000100029 PES1 LAML 0.0047 high
ENSG00000100029 PES1 GBM 0.032 low
ENSG00000100029 PES1 SKCM 0.033 high
ENSG00000100029 PES1 CESC 0.05 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000100029 PES1 THYM Del 0.970980 0.045771 0.419966 0.138211
ENSG00000100029 PES1 BLCA Amp 2.572093 0.226839 0.641069 0.203431
ENSG00000100029 PES1 UCEC Amp 2.303209 0.138983 0.674251 0.107607