Ensembl ID
ENSG00000100029
Gene ID
23481
Accession
8848
Gene Symbol
PES1
Alias
PES;NOP7
Full Name
pescadillo ribosomal biogenesis factor 1
Position
22 : 30576625 - 30607083
Length
30459 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs rRNA RBP type
Canonical_RBPs
Summary
This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9. [provided by RefSeq, Aug 2011]
ENSG00000100029 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000100029
PES1
0.50
5.02e-21
KIRC
ENSG00000100029
PES1
0.53
4.84e-16
BRCA
ENSG00000100029
PES1
0.84
5.08e-19
COAD
ENSG00000100029
PES1
1.18
1.16e-40
LUSC
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000100029
PES1
cancer
22304779
ENSG00000100029
PES1
breast cancer
22820289
ENSG00000100029
PES1
breast cancer
22820293
ENSG00000100029
PES1
Colon Cancer
22860098
ENSG00000100029
PES1
colorectal cancer
23333390
ENSG00000100029
PES1
ovarian cancer
24376209
ENSG00000100029
PES1
tumor
25557119
ENSG00000100029
PES1
gastric cancer
26423399
ENSG00000100029
PES1
tumor
27409667
ENSG00000100029
PES1
tumor
28143451
ENSG00000100029
PES1
gastric cancer
30172011
ENSG00000100029
PES1
tumor
30705367
ENSG00000100029
PES1
cancers
31106266
ENSG00000100029
PES1
liver cancer
31127852
ENSG00000100029
PES1
pancreatic cancer
31718704
ENSG00000100029
PES1
Liver Cancer
31814761
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000100029
PES1
SARC
0.019
high
show
ENSG00000100029
PES1
STAD
0.0015
low
show
ENSG00000100029
PES1
PAAD
0.042
high
show
ENSG00000100029
PES1
UCEC
0.028
high
show
ENSG00000100029
PES1
THCA
0.045
low
show
ENSG00000100029
PES1
ACC
0.00061
high
show
ENSG00000100029
PES1
LUSC
0.022
low
show
ENSG00000100029
PES1
HNSC
0.003
high
show
ENSG00000100029
PES1
READ
0.00018
low
show
ENSG00000100029
PES1
KIRP
0.04
low
show
ENSG00000100029
PES1
KICH
0.0054
high
show
ENSG00000100029
PES1
LUAD
0.00079
high
show
ENSG00000100029
PES1
PCPG
0.014
low
show
ENSG00000100029
PES1
COAD
0.027
high
show
ENSG00000100029
PES1
DLBC
0.015
low
show
ENSG00000100029
PES1
KIRC
0.012
low
show
ENSG00000100029
PES1
PRAD
0.0082
high
show
ENSG00000100029
PES1
BLCA
0.02
high
show
ENSG00000100029
PES1
LAML
0.0047
high
show
ENSG00000100029
PES1
GBM
0.032
low
show
ENSG00000100029
PES1
SKCM
0.033
high
show
ENSG00000100029
PES1
CESC
0.05
low
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000100029
PES1
THYM
Del
0.970980
0.045771
0.419966
0.138211
ENSG00000100029
PES1
BLCA
Amp
2.572093
0.226839
0.641069
0.203431
ENSG00000100029
PES1
UCEC
Amp
2.303209
0.138983
0.674251
0.107607
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