Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerSARS-COV-2Dengue
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Kinase
Localizations Stress granule or P-body
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000096063 Gene ID 6732 Accession 11305
Symbol SRPK1 Alias SFRSK1 Full Name SRSF protein kinase 1
Status Confidence Length 88377 bases Strand Minus strand
Position 6 : 35832966 - 35921342 RNA binding domain N.A.
Summary This gene encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. Alternative splicing of this gene results in multiple transcript variants. Additional alternatively spliced transcript variants have been described for this gene, but their full length nature have not been determined.[provided by RefSeq, Jul 2010]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
26013829 Intra-domain Cross-talk Regulates Serine-arginine Protein Kinase 1-dependent Phosphorylation and Splicing Function of Transformer 2β1. A Michael Jamros 2015-07-10 The Journal of biological chemistry
26062451 The structure of the folded domain from the signature multifunctional protein ICP27 from herpes simplex virus-1 reveals an intertwined dimer. B Richard Tunnicliffe 2015-06-11 Scientific reports
31666932 Splicing regulatory factors in breast cancer hallmarks and disease progression. Esmee Koedoot 2019-10-15 Oncotarget
30566530 Hepatitis B virus core protein phosphorylation: Identification of the SRPK1 target sites and impact of their occupancy on RNA binding and capsid structure. Julia Heger-Stevic 2018-12-01 PLoS pathogens
26273588 Splicing Regulators and Their Roles in Cancer Biology and Therapy. Roméria Maria MR da 2015-01-01 BioMed research international
30799147 System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection. Manuel Garcia-Moreno 2019-04-04 Molecular cell
31641093 Molecular Mechanism of SR Protein Kinase 1 Inhibition by the Herpes Virus Protein ICP27. B Richard Tunnicliffe 2019-10-22 mBio
18022399 RNA association or phosphorylation of the RS domain prevents aggregation of RS domain-containing proteins. Eleni Nikolakaki 2008-02-01 Biochimica et biophysica acta
37250098 Establishing a genomic radiation-age association for space exploration supplements lung disease differentiation. A Nathan Ruprecht 2023-01-01 Frontiers in public health
36627683 The SARS-CoV-2 nucleocapsid protein: its role in the viral life cycle, structure and functions, and use as a potential target in the development of vaccines and diagnostics. Wenbing Wu 2023-01-10 Virology journal
34029587 Arginine methylation of SARS-Cov-2 nucleocapsid protein regulates RNA binding, its ability to suppress stress granule formation, and viral replication. Ting Cai 2021-07-01 The Journal of biological chemistry

Transcripts

Name Transcript ID bp Protein Translation ID

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
24018Obesity6.1830000E-005-
24021Obesity7.3100000E-005-
24045Obesity5.2210000E-005-
26478Blood Pressure7.7460000E-005-
38645Platelet Function Tests1.7088800E-005-
40209Platelet Function Tests7.4700000E-006-
40216Platelet Function Tests1.3802800E-005-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000096063homo_sapiensENSP0000021565940.054526.4305homo_sapiensENSP0000036293122.442714.8092
ENSG00000096063homo_sapiensENSP0000037896819.117612.1324homo_sapiensENSP0000036293123.816815.1145
ENSG00000096063homo_sapiensENSP0000033368542.582427.7473homo_sapiensENSP0000036293123.664115.4198
ENSG00000096063homo_sapiensENSP0000034648422.530913.7346homo_sapiensENSP0000036293122.290113.5878
ENSG00000096063homo_sapiensENSP0000050169223.417715.1899homo_sapiensENSP0000036293122.595414.6565
ENSG00000096063homo_sapiensENSP0000026184519.694912.0666homo_sapiensENSP0000036293121.679413.2824
ENSG00000096063homo_sapiensENSP0000037726268.240356.6524homo_sapiensENSP0000036293172.824460.458
ENSG00000096063homo_sapiensENSP0000033769126.654416.9118homo_sapiensENSP0000036293122.137414.0458
ENSG00000096063homo_sapiensENSP0000035530431.264917.8998homo_sapiensENSP000003629312011.4504
ENSG00000096063homo_sapiensENSP0000038462527.514219.1651homo_sapiensENSP0000036293122.137415.4198
ENSG00000096063homo_sapiensENSP0000038323423.850113.799homo_sapiensENSP0000036293121.37412.3664
ENSG00000096063homo_sapiensENSP0000036330435.36322.4824homo_sapiensENSP0000036293123.053414.6565
ENSG00000096063homo_sapiensENSP0000049343532.758620.6897homo_sapiensENSP0000036293123.206114.6565
ENSG00000096063homo_sapiensENSP0000026302539.577826.3852homo_sapiensENSP0000036293122.900815.2672
ENSG00000096063homo_sapiensENSP0000021583240.277825.8333homo_sapiensENSP0000036293122.137414.1985
ENSG00000096063homo_sapiensENSP0000022979442.528.3333homo_sapiensENSP0000036293123.358815.5725
ENSG00000096063homo_sapiensENSP0000021128741.369926.8493homo_sapiensENSP0000036293123.053414.9618
ENSG00000096063homo_sapiensENSP0000035911972.310458.7302homo_sapiensENSP0000036293162.595450.8397
ENSG00000096063homo_sapiensENSP0000039456035.849122.8774homo_sapiensENSP0000036293123.206114.8092

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000096063homo_sapiensENSP0000036293197.557396.6412nomascus_leucogenysENSNLEP0000004543897.260396.347
ENSG00000096063homo_sapiensENSP0000036293199.389399.2366pan_paniscusENSPPAP0000001339097.019496.8703
ENSG00000096063homo_sapiensENSP0000036293199.847399.8473pongo_abeliiENSPPYP0000002889193.428693.4286
ENSG00000096063homo_sapiensENSP0000036293199.847399.6947pan_troglodytesENSPTRP0000003350399.847399.6947
ENSG00000096063homo_sapiensENSP00000362931100100gorilla_gorillaENSGGOP00000013238100100
ENSG00000096063homo_sapiensENSP0000036293188.396983.5115ornithorhynchus_anatinusENSOANP0000003752666.475362.8014
ENSG00000096063homo_sapiensENSP0000036293192.671887.6336sarcophilus_harrisiiENSSHAP0000001518987.590282.8283
ENSG00000096063homo_sapiensENSP0000036293174.045870.9924notamacropus_eugeniiENSMEUP0000001524159.950657.4784
ENSG00000096063homo_sapiensENSP0000036293169.465767.7863choloepus_hoffmanniENSCHOP0000000700495.789593.4737
ENSG00000096063homo_sapiensENSP0000036293196.641295.1145dasypus_novemcinctusENSDNOP0000001207776.265175.0602
ENSG00000096063homo_sapiensENSP0000036293161.679460.458erinaceus_europaeusENSEEUP0000000941449.328448.3517
ENSG00000096063homo_sapiensENSP0000036293183.816881.6794echinops_telfairiENSETEP0000001067568.198866.4596
ENSG00000096063homo_sapiensENSP0000036293199.08498.3206callithrix_jacchusENSCJAP0000009355292.187591.4773
ENSG00000096063homo_sapiensENSP0000036293181.37478.7786macaca_nemestrinaENSMNEP0000002277492.695789.7391
ENSG00000096063homo_sapiensENSP0000036293184.580281.6794mandrillus_leucophaeusENSMLEP0000003483892.026688.8704
ENSG00000096063homo_sapiensENSP0000036293190.534389.1603tursiops_truncatusENSTTRP0000001361572.493971.3936
ENSG00000096063homo_sapiensENSP0000036293197.251996.1832vulpes_vulpesENSVVUP0000003657792.857191.8367
ENSG00000096063homo_sapiensENSP0000036293194.503891.6031mus_spretusMGP_SPRETEiJ_P004557595.084592.1659
ENSG00000096063homo_sapiensENSP0000036293197.709995.8779equus_asinusENSEASP0000506281789.012587.3435
ENSG00000096063homo_sapiensENSP0000036293193.129891.2977capra_hircusENSCHIP0000001220594.573692.7132
ENSG00000096063homo_sapiensENSP0000036293195.725294.9618loxodonta_africanaENSLAFP0000000008696.610295.8398
ENSG00000096063homo_sapiensENSP0000036293197.709996.4885panthera_leoENSPLOP0000002152497.709996.4885
ENSG00000096063homo_sapiensENSP0000036293196.793995.7252ailuropoda_melanoleucaENSAMEP0000000057294.485893.4426
ENSG00000096063homo_sapiensENSP0000036293196.946695.5725bos_indicus_hybridENSBIXP0000500590489.185487.9213
ENSG00000096063homo_sapiensENSP0000036293197.709996.6412oryctolagus_cuniculusENSOCUP0000003537177.201476.3571
ENSG00000096063homo_sapiensENSP0000036293191.14586.2595equus_caballusENSECAP0000007256281.004176.6621
ENSG00000096063homo_sapiensENSP0000036293197.099296.0305canis_lupus_familiarisENSCAFP0084501012492.711491.691
ENSG00000096063homo_sapiensENSP0000036293194.351192.8244panthera_pardusENSPPRP0000001285196.865295.2978
ENSG00000096063homo_sapiensENSP0000036293197.862696.4885marmota_marmota_marmotaENSMMMP0000002792197.862696.4885
ENSG00000096063homo_sapiensENSP0000036293197.709996.1832balaenoptera_musculusENSBMSP0001001628997.709996.1832
ENSG00000096063homo_sapiensENSP0000036293187.633686.2595cavia_porcellusENSCPOP0000000376496.147494.6399
ENSG00000096063homo_sapiensENSP0000036293196.793995.7252felis_catusENSFCAP0000002453394.485893.4426
ENSG00000096063homo_sapiensENSP0000036293184.274881.5267ursus_americanusENSUAMP0000001172679.083176.5043
ENSG00000096063homo_sapiensENSP0000036293192.061187.3282monodelphis_domesticaENSMODP0000004721487.645383.1395
ENSG00000096063homo_sapiensENSP0000036293196.793995.4198bison_bison_bisonENSBBBP0000000470096.793995.4198
ENSG00000096063homo_sapiensENSP0000036293197.557396.1832monodon_monocerosENSMMNP0001501412297.557396.1832
ENSG00000096063homo_sapiensENSP0000036293196.641293.4351sus_scrofaENSSSCP0000000168876.173373.6462
ENSG00000096063homo_sapiensENSP0000036293193.282491.9084microcebus_murinusENSMICP0000000245595.468894.0625
ENSG00000096063homo_sapiensENSP0000036293192.519190.8397microcebus_murinusENSMICP0000003739297.115495.3526
ENSG00000096063homo_sapiensENSP0000036293188.85587.6336octodon_degusENSODEP000000228689795.6667
ENSG00000096063homo_sapiensENSP0000036293181.068775.7252jaculus_jaculusENSJJAP0000001957087.768681.9835
ENSG00000096063homo_sapiensENSP0000036293196.793995.5725ovis_aries_rambouilletENSOARP0002002966396.793995.5725
ENSG00000096063homo_sapiensENSP0000036293181.526780.1527ursus_maritimusENSUMAP0000001392897.445395.8029
ENSG00000096063homo_sapiensENSP0000036293191.755789.9237ochotona_princepsENSOPRP0000000077175.313373.8095
ENSG00000096063homo_sapiensENSP0000036293197.557396.1832delphinapterus_leucasENSDLEP0000002815797.557396.1832
ENSG00000096063homo_sapiensENSP0000036293197.862696.4885physeter_catodonENSPCTP0000502609893.440292.1283
ENSG00000096063homo_sapiensENSP0000036293194.503891.2977mus_caroliMGP_CAROLIEiJ_P004366595.084591.8587
ENSG00000096063homo_sapiensENSP0000036293194.045890.9924mus_musculusENSMUSP0000011625995.061791.9753
ENSG00000096063homo_sapiensENSP0000036293188.549685.8015dipodomys_ordiiENSDORP0000002059193.851190.9385
ENSG00000096063homo_sapiensENSP0000036293197.557396.1832mustela_putorius_furoENSMPUP0000000378897.557396.1832
ENSG00000096063homo_sapiensENSP0000036293198.473398.1679aotus_nancymaaeENSANAP0000000678896.125295.8271
ENSG00000096063homo_sapiensENSP0000036293198.015397.4046saimiri_boliviensis_boliviensisENSSBOP0000003636198.769298.1538
ENSG00000096063homo_sapiensENSP0000036293194.503892.6718vicugna_pacosENSVPAP0000001023482.864881.2584
ENSG00000096063homo_sapiensENSP0000036293150.992450.5344tupaia_belangeriENSTBEP0000000643740.781440.4151
ENSG00000096063homo_sapiensENSP0000036293194.809292.3664mesocricetus_auratusENSMAUP0000000733195.391792.9339
ENSG00000096063homo_sapiensENSP0000036293197.251995.8779phocoena_sinusENSPSNP0000002593797.251995.8779
ENSG00000096063homo_sapiensENSP0000036293197.862696.0305camelus_dromedariusENSCDRP0000501481397.862696.0305
ENSG00000096063homo_sapiensENSP0000036293197.862697.4046carlito_syrichtaENSTSYP0000000208595.529195.082
ENSG00000096063homo_sapiensENSP0000036293196.946695.8779panthera_tigris_altaicaENSPTIP0000001855494.634993.5917
ENSG00000096063homo_sapiensENSP0000036293194.198591.4504rattus_norvegicusENSRNOP0000000061294.198591.4504
ENSG00000096063homo_sapiensENSP0000036293198.167997.0992prolemur_simusENSPSMP0000001513995.827194.7839
ENSG00000096063homo_sapiensENSP0000036293195.114593.2824microtus_ochrogasterENSMOCP0000001671495.259993.4251
ENSG00000096063homo_sapiensENSP0000036293184.122181.374sorex_araneusENSSARP0000000386567.113364.9208
ENSG00000096063homo_sapiensENSP0000036293195.114592.8244peromyscus_maniculatus_bairdiiENSPEMP0000000882095.259992.9664
ENSG00000096063homo_sapiensENSP0000036293119.08416.9466bos_mutusENSBMUP0000000239675.301266.8675
ENSG00000096063homo_sapiensENSP0000036293125.648923.6641bos_mutusENSBMUP0000000242793.854886.5922
ENSG00000096063homo_sapiensENSP0000036293194.351191.4504mus_spicilegusENSMSIP0000001040194.930992.0123
ENSG00000096063homo_sapiensENSP0000036293194.198592.2137cricetulus_griseus_chok1gshdENSCGRP0000102034495.069393.0663
ENSG00000096063homo_sapiensENSP0000036293188.549686.5649pteropus_vampyrusENSPVAP0000001411576.015774.3119
ENSG00000096063homo_sapiensENSP0000036293193.587890.8397myotis_lucifugusENSMLUP0000001003195.482992.6791
ENSG00000096063homo_sapiensENSP0000036293192.519187.9389vombatus_ursinusENSVURP0001002491487.69983.3575
ENSG00000096063homo_sapiensENSP0000036293197.862695.8779rhinolophus_ferrumequinumENSRFEP0001003076797.862695.8779
ENSG00000096063homo_sapiensENSP0000036293196.946695.5725neovison_visonENSNVIP0000001424394.634993.2936
ENSG00000096063homo_sapiensENSP0000036293194.045892.5191bos_taurusENSBTAP0000002239695.503993.9535
ENSG00000096063homo_sapiensENSP0000036293190.381787.7863heterocephalus_glaber_femaleENSHGLP0000005072281.655279.3103
ENSG00000096063homo_sapiensENSP0000036293181.068778.3206rhinopithecus_bietiENSRBIP0000002581392.832289.6853
ENSG00000096063homo_sapiensENSP0000036293180.91679.8473canis_lupus_dingoENSCAFP0002000880496.715395.438
ENSG00000096063homo_sapiensENSP0000036293197.557396.3359sciurus_vulgarisENSSVLP0000500932595.23194.0387
ENSG00000096063homo_sapiensENSP0000036293195.267293.7405sciurus_vulgarisENSSVLP0000501477496.594495.0464
ENSG00000096063homo_sapiensENSP0000036293192.366487.0229phascolarctos_cinereusENSPCIP0000002849487.175882.1326
ENSG00000096063homo_sapiensENSP0000036293188.091686.2595procavia_capensisENSPCAP0000000086070.624269.1554
ENSG00000096063homo_sapiensENSP0000036293193.129889.1603nannospalax_galiliENSNGAP0000001358494.573690.5426
ENSG00000096063homo_sapiensENSP0000036293196.946695.5725bos_grunniensENSBGRP0000002300892.565691.2536
ENSG00000096063homo_sapiensENSP0000036293188.85584.2748chinchilla_lanigeraENSCLAP0000002571476.882472.9194
ENSG00000096063homo_sapiensENSP0000036293196.335993.8931chinchilla_lanigeraENSCLAP0000001533897.076994.6154
ENSG00000096063homo_sapiensENSP0000036293193.435191.4504cervus_hanglu_yarkandensisENSCHYP0000001851482.147780.4027
ENSG00000096063homo_sapiensENSP0000036293197.557396.1832catagonus_wagneriENSCWAP0000001135297.557396.1832
ENSG00000096063homo_sapiensENSP0000036293197.862696.3359ictidomys_tridecemlineatusENSSTOP0000001230397.862696.3359
ENSG00000096063homo_sapiensENSP0000036293194.961893.4351otolemur_garnettiiENSOGAP0000000871697.339695.7747
ENSG00000096063homo_sapiensENSP0000036293199.08498.4733cebus_imitatorENSCCAP0000002984099.08498.4733
ENSG00000096063homo_sapiensENSP0000036293197.709996.3359urocitellus_parryiiENSUPAP0001001957497.709996.3359
ENSG00000096063homo_sapiensENSP0000036293196.946695.7252moschus_moschiferusENSMMSP0000000721196.946695.7252
ENSG00000096063homo_sapiensENSP0000036293181.068778.1679rhinopithecus_roxellanaENSRROP0000003009492.832289.5105
ENSG00000096063homo_sapiensENSP0000036293193.740590.5343mus_pahariMGP_PahariEiJ_P005596494.316491.0906
ENSG00000096063homo_sapiensENSP0000036293193.435191.7557propithecus_coquereliENSPCOP0000000050794.153892.4615
ENSG00000096063homo_sapiensENSP0000036293122.137414.1985caenorhabditis_elegansB0218.3.138.461524.6684
ENSG00000096063homo_sapiensENSP0000036293123.206113.7405caenorhabditis_elegansF42G8.3a.137.810922.3881
ENSG00000096063homo_sapiensENSP0000036293158.015345.3435caenorhabditis_elegansB0464.5a.137.886329.6112
ENSG00000096063homo_sapiensENSP0000036293121.068712.8244caenorhabditis_elegansT07A9.3.235.384621.5385
ENSG00000096063homo_sapiensENSP0000036293120.152712.6718caenorhabditis_elegansZC416.4.139.75925
ENSG00000096063homo_sapiensENSP0000036293122.137412.8244caenorhabditis_elegansC36B1.10.138.057722.0472
ENSG00000096063homo_sapiensENSP0000036293121.832113.1298caenorhabditis_elegansY106G6E.1.137.532822.5722
ENSG00000096063homo_sapiensENSP0000036293148.244333.1298drosophila_melanogasterFBpp00739174027.4684
ENSG00000096063homo_sapiensENSP0000036293162.290148.7023drosophila_melanogasterFBpp042815740.436131.6155
ENSG00000096063homo_sapiensENSP0000036293154.809244.1221ciona_intestinalisENSCINP0000001387254.725644.0549
ENSG00000096063homo_sapiensENSP0000036293145.648937.0992petromyzon_marinusENSPMAP0000000901153.297743.3155
ENSG00000096063homo_sapiensENSP0000036293162.748150.0763eptatretus_burgeriENSEBUP0000002562953.44642.6528
ENSG00000096063homo_sapiensENSP0000036293181.832170.8397latimeria_chalumnaeENSLACP0000001434879.525268.8427
ENSG00000096063homo_sapiensENSP0000036293167.175659.8473lepisosteus_oculatusENSLOCP0000001372566.869359.5745
ENSG00000096063homo_sapiensENSP0000036293160.763450.3817clupea_harengusENSCHAP0000003989465.139154.0098
ENSG00000096063homo_sapiensENSP0000036293165.343555.5725danio_rerioENSDARP0000004297165.045655.3191
ENSG00000096063homo_sapiensENSP0000036293162.595451.4504carassius_auratusENSCARP0000008185663.174151.926
ENSG00000096063homo_sapiensENSP0000036293163.511553.4351carassius_auratusENSCARP0000012176464.098653.9291
ENSG00000096063homo_sapiensENSP0000036293163.206153.7405astyanax_mexicanusENSAMXP0000003978161.79152.5373
ENSG00000096063homo_sapiensENSP0000036293162.442752.8244ictalurus_punctatusENSIPUP0000003576263.509353.7267
ENSG00000096063homo_sapiensENSP0000036293160.610749.1603esox_luciusENSELUP0000006676361.550449.9225
ENSG00000096063homo_sapiensENSP0000036293162.595453.4351electrophorus_electricusENSEEEP0000001398364.364254.9451
ENSG00000096063homo_sapiensENSP0000036293161.221452.2137oncorhynchus_kisutchENSOKIP0000506895669.982659.6859
ENSG00000096063homo_sapiensENSP0000036293155.877948.3969oncorhynchus_mykissENSOMYP0000006015473.263.4
ENSG00000096063homo_sapiensENSP0000036293146.870234.6565oncorhynchus_mykissENSOMYP0000011522646.096134.0841
ENSG00000096063homo_sapiensENSP0000036293165.038254.9618salmo_salarENSSSAP0000009856366.87656.5149
ENSG00000096063homo_sapiensENSP0000036293164.885554.1985salmo_salarENSSSAP0000001812565.184154.4479
ENSG00000096063homo_sapiensENSP0000036293158.015348.7023salmo_truttaENSSTUP0000003630867.857156.9643
ENSG00000096063homo_sapiensENSP0000036293156.946648.0916salmo_truttaENSSTUP0000006339363.979454.0309
ENSG00000096063homo_sapiensENSP0000036293161.526751.6031gadus_morhuaENSGMOP0000005378262.968852.8125
ENSG00000096063homo_sapiensENSP0000036293164.122154.3511fundulus_heteroclitusENSFHEP0000000504464.122154.3511
ENSG00000096063homo_sapiensENSP0000036293165.648955.4198poecilia_reticulataENSPREP0000000353865.349555.1672
ENSG00000096063homo_sapiensENSP0000036293165.801555.8779xiphophorus_maculatusENSXMAP0000003916359.203350.2747
ENSG00000096063homo_sapiensENSP0000036293164.274854.1985oryzias_latipesENSORLP0000002017165.069554.8686
ENSG00000096063homo_sapiensENSP0000036293160.763449.6183cyclopterus_lumpusENSCLMP0000501643160.30349.2424
ENSG00000096063homo_sapiensENSP0000036293163.358852.3664oreochromis_niloticusENSONIP0000002758162.974252.0486
ENSG00000096063homo_sapiensENSP0000036293163.053451.4504haplochromis_burtoniENSHBUP0000002153263.149851.5291
ENSG00000096063homo_sapiensENSP0000036293161.832150.3817astatotilapia_callipteraENSACLP0000001122762.693551.0836
ENSG00000096063homo_sapiensENSP0000036293163.816851.2977sparus_aurataENSSAUP0001003652463.622551.1416
ENSG00000096063homo_sapiensENSP0000036293164.274853.1298lates_calcariferENSLCAP0001000763963.213252.2523
ENSG00000096063homo_sapiensENSP0000036293159.08452.2137xenopus_tropicalisENSXETP0000006540957.934151.1976
ENSG00000096063homo_sapiensENSP0000036293189.77182.9008chrysemys_picta_belliiENSCPBP0000002498576.562570.7031
ENSG00000096063homo_sapiensENSP0000036293184.732875.8779sphenodon_punctatusENSSPUP0000001811185.253576.3441
ENSG00000096063homo_sapiensENSP0000036293184.427576.3359crocodylus_porosusENSCPRP0000500416183.787975.7576
ENSG00000096063homo_sapiensENSP0000036293176.488568.2443laticauda_laticaudataENSLLTP0000001814472.294464.5022
ENSG00000096063homo_sapiensENSP0000036293123.816821.8321notechis_scutatusENSNSUP0000000168290.173482.659
ENSG00000096063homo_sapiensENSP0000036293116.183214.6565notechis_scutatusENSNSUP0000001999894.642985.7143
ENSG00000096063homo_sapiensENSP0000036293123.511421.5267notechis_scutatusENSNSUP0000001999788.505781.0345
ENSG00000096063homo_sapiensENSP0000036293116.183214.6565notechis_scutatusENSNSUP0000000157094.642985.7143
ENSG00000096063homo_sapiensENSP0000036293184.885576.3359pseudonaja_textilisENSPTXP0000001096185.407176.8049
ENSG00000096063homo_sapiensENSP0000036293169.31360.7634pseudonaja_textilisENSPTXP0000002788383.455973.1618
ENSG00000096063homo_sapiensENSP0000036293185.343577.7099anas_platyrhynchos_platyrhynchosENSAPLP0000000288084.186776.6566
ENSG00000096063homo_sapiensENSP0000036293184.885576.0305gallus_gallusENSGALP0001003979079.202370.9402
ENSG00000096063homo_sapiensENSP0000036293121.068718.4733meleagris_gallopavoENSMGAP0000003443373.796864.7059
ENSG00000096063homo_sapiensENSP0000036293168.85561.0687meleagris_gallopavoENSMGAP0000000010481.851272.5953
ENSG00000096063homo_sapiensENSP0000036293184.122176.3359serinus_canariaENSSCAP0000002189283.866176.1035
ENSG00000096063homo_sapiensENSP0000036293184.427576.6412parus_majorENSPMJP0000001638384.170576.4079
ENSG00000096063homo_sapiensENSP0000036293183.969574.9618anolis_carolinensisENSACAP0000001681883.459874.5068
ENSG00000096063homo_sapiensENSP0000036293161.679449.771neolamprologus_brichardiENSNBRP0000001761865.905453.1811
ENSG00000096063homo_sapiensENSP0000036293185.038275.7252naja_najaENSNNAP0000000109385.560776.1905
ENSG00000096063homo_sapiensENSP0000036293187.938979.6947podarcis_muralisENSPMRP0000002342974.805267.7922
ENSG00000096063homo_sapiensENSP0000036293171.14563.9695geospiza_fortisENSGFOP0000001404383.96475.4955
ENSG00000096063homo_sapiensENSP0000036293183.816875.4198taeniopygia_guttataENSTGUP0000003795882.308874.063
ENSG00000096063homo_sapiensENSP0000036293125.954223.2061erpetoichthys_calabaricusENSECRP0000001929062.271155.6777
ENSG00000096063homo_sapiensENSP0000036293116.335914.5038erpetoichthys_calabaricusENSECRP0000001931288.429778.5124
ENSG00000096063homo_sapiensENSP0000036293164.580254.6565kryptolebias_marmoratusENSKMAP0000000726663.704853.9157
ENSG00000096063homo_sapiensENSP0000036293186.259577.8626salvator_merianaeENSSMRP0000002723074.244467.0171
ENSG00000096063homo_sapiensENSP0000036293158.473350.0763oryzias_javanicusENSOJAP0000002030170.275260.1835
ENSG00000096063homo_sapiensENSP0000036293155.114548.2443amphilophus_citrinellusENSACIP0000001787369.423160.7692
ENSG00000096063homo_sapiensENSP0000036293163.511552.2137dicentrarchus_labraxENSDLAP0000502742463.414652.1341
ENSG00000096063homo_sapiensENSP0000036293164.427553.7405amphiprion_perculaENSAPEP0000000809057.808248.2192
ENSG00000096063homo_sapiensENSP0000036293156.641247.9389oryzias_sinensisENSOSIP0000003219667.332156.9873
ENSG00000096063homo_sapiensENSP0000036293185.343578.1679pelodiscus_sinensisENSPSIP0000000708487.343880
ENSG00000096063homo_sapiensENSP0000036293189.77182.9008gopherus_evgoodeiENSGEVP0000500168980.991774.7934
ENSG00000096063homo_sapiensENSP0000036293186.106980chelonoidis_abingdoniiENSCABP0000001049884.939878.9157
ENSG00000096063homo_sapiensENSP0000036293165.190854.6565seriola_dumeriliENSSDUP0000000080964.307253.9157
ENSG00000096063homo_sapiensENSP0000036293163.053452.2137cottoperca_gobioENSCGOP0000000894562.386751.6616
ENSG00000096063homo_sapiensENSP0000036293186.259577.7099struthio_camelus_australisENSSCUP0000000524185.99777.4734
ENSG00000096063homo_sapiensENSP0000036293184.885577.0992anser_brachyrhynchusENSABRP0000001514078.309971.1268
ENSG00000096063homo_sapiensENSP0000036293162.900850.9924gasterosteus_aculeatusENSGACP0000001016965.500853.1002
ENSG00000096063homo_sapiensENSP0000036293164.885552.6718cynoglossus_semilaevisENSCSEP0000000794554.071243.8931
ENSG00000096063homo_sapiensENSP0000036293166.106955.5725poecilia_formosaENSPFOP0000001802965.805555.3191
ENSG00000096063homo_sapiensENSP0000036293165.648955.2672myripristis_murdjanENSMMDP0000500607565.151554.8485
ENSG00000096063homo_sapiensENSP0000036293163.969552.3664sander_luciopercaENSSLUP0000003427263.581252.0486
ENSG00000096063homo_sapiensENSP0000036293188.091680strigops_habroptilaENSSHBP0000500960087.957379.8781
ENSG00000096063homo_sapiensENSP0000036293154.045846.4122amphiprion_ocellarisENSAOCP0000001435974.526364
ENSG00000096063homo_sapiensENSP0000036293116.335914.3511amphiprion_ocellarisENSAOCP0000000759388.429777.686
ENSG00000096063homo_sapiensENSP0000036293185.343579.084terrapene_carolina_triunguisENSTMTP0000002005688.309681.8325
ENSG00000096063homo_sapiensENSP0000036293159.08450.9924hucho_huchoENSHHUP0000005464471.534261.7375
ENSG00000096063homo_sapiensENSP0000036293161.984752.0611hucho_huchoENSHHUP0000003417663.93753.7008
ENSG00000096063homo_sapiensENSP0000036293163.664151.9084betta_splendensENSBSLP0000001509762.990951.3595
ENSG00000096063homo_sapiensENSP0000036293163.969554.5038pygocentrus_nattereriENSPNAP0000002658862.630853.3632
ENSG00000096063homo_sapiensENSP0000036293162.900853.5878anabas_testudineusENSATEP0000003521261.861952.7027
ENSG00000096063homo_sapiensENSP0000036293156.335945.8015ciona_savignyiENSCSAVP0000000931751.178941.6089
ENSG00000096063homo_sapiensENSP0000036293151.14536.3359saccharomyces_cerevisiaeYMR216C45.148232.0755
ENSG00000096063homo_sapiensENSP0000036293121.984713.1298saccharomyces_cerevisiaeYKL161C33.256419.8614
ENSG00000096063homo_sapiensENSP0000036293122.748113.8931saccharomyces_cerevisiaeYHR030C30.785118.8017
ENSG00000096063homo_sapiensENSP0000036293158.167950.687seriola_lalandi_dorsalisENSSLDP0000001171563.60655.4257
ENSG00000096063homo_sapiensENSP0000036293156.793948.855labrus_bergyltaENSLBEP0000001414072.798462.6223
ENSG00000096063homo_sapiensENSP0000036293155.572547.4809pundamilia_nyerereiENSPNYP0000001087271.232960.8611
ENSG00000096063homo_sapiensENSP0000036293163.358852.3664mastacembelus_armatusENSMAMP0000001342563.165952.207
ENSG00000096063homo_sapiensENSP0000036293165.801554.5038stegastes_partitusENSSPAP0000001598665.204254.0091
ENSG00000096063homo_sapiensENSP0000036293139.389334.8092oncorhynchus_tshawytschaENSOTSP0000500924668.43560.4775
ENSG00000096063homo_sapiensENSP0000036293165.343554.3511acanthochromis_polyacanthusENSAPOP0000001379163.880653.1343
ENSG00000096063homo_sapiensENSP0000036293187.480980.1527aquila_chrysaetos_chrysaetosENSACCP0002002205787.082179.7872
ENSG00000096063homo_sapiensENSP0000036293158.931350.229nothobranchius_furzeriENSNFUP0001502262057.611949.1045
ENSG00000096063homo_sapiensENSP0000036293163.511554.6565cyprinodon_variegatusENSCVAP0000000656363.125954.3247
ENSG00000096063homo_sapiensENSP0000036293165.648954.6565larimichthys_croceaENSLCRP0000500857165.052954.1604
ENSG00000096063homo_sapiensENSP0000036293156.641248.7023takifugu_rubripesENSTRUP0000002046973.611163.2937
ENSG00000096063homo_sapiensENSP0000036293187.175679.2366ficedula_albicollisENSFALP0000000373487.175679.2366
ENSG00000096063homo_sapiensENSP0000036293151.755744.8855hippocampus_comesENSHCOP0000002224872.127762.5532
ENSG00000096063homo_sapiensENSP0000036293162.595452.9771cyprinus_carpio_carpioENSCCRP0000005678958.073749.1501
ENSG00000096063homo_sapiensENSP0000036293163.816853.2824cyprinus_carpio_carpioENSCCRP0000016910763.914453.3639
ENSG00000096063homo_sapiensENSP0000036293185.190876.0305coturnix_japonicaENSCJPP0000500371485.978476.7334
ENSG00000096063homo_sapiensENSP0000036293165.954255.4198poecilia_latipinnaENSPLAP0000000402965.653555.1672
ENSG00000096063homo_sapiensENSP0000036293163.206152.6718sinocyclocheilus_grahamiENSSGRP0000010304362.443452.0362
ENSG00000096063homo_sapiensENSP0000036293150.534438.0153sinocyclocheilus_grahamiENSSGRP0000005396558.480643.9929
ENSG00000096063homo_sapiensENSP0000036293164.885553.1298maylandia_zebraENSMZEP0000500003265.084253.2925
ENSG00000096063homo_sapiensENSP0000036293156.030547.6336tetraodon_nigroviridisENSTNIP0000000958170.038259.542
ENSG00000096063homo_sapiensENSP0000036293163.816856.1832paramormyrops_kingsleyaeENSPKIP0000002524550.851644.7689
ENSG00000096063homo_sapiensENSP0000036293163.206154.6565scleropages_formosusENSSFOP0001503699066.559557.5563
ENSG00000096063homo_sapiensENSP0000036293165.038254.0458scophthalmus_maximusENSSMAP0000001129564.545553.6364
ENSG00000096063homo_sapiensENSP0000036293162.137451.2977oryzias_melastigmaENSOMEP0000002120963.29752.2551

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000245involved_in spliceosomal complex assembly1IBAHomo_sapiens(9606)Process
GO:0000287enables magnesium ion binding1IDAHomo_sapiens(9606)Function
GO:0000785part_of chromatin1IDAHomo_sapiens(9606)Component
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0004672enables protein kinase activity1TASHomo_sapiens(9606)Function
GO:0004674enables protein serine/threonine kinase activity2IBA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IDAHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus2IBA,IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0005783located_in endoplasmic reticulum1IEAHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0005886located_in plasma membrane1IDAHomo_sapiens(9606)Component
GO:0006468involved_in protein phosphorylation1IDAHomo_sapiens(9606)Process
GO:0007059involved_in chromosome segregation1IDAHomo_sapiens(9606)Process
GO:0008380involved_in RNA splicing1TASHomo_sapiens(9606)Process
GO:0016363located_in nuclear matrix1IEAHomo_sapiens(9606)Component
GO:0016607located_in nuclear speck1IDAHomo_sapiens(9606)Component
GO:0018105involved_in peptidyl-serine phosphorylation1IBAHomo_sapiens(9606)Process
GO:0035092involved_in sperm DNA condensation1TASHomo_sapiens(9606)Process
GO:0035556involved_in intracellular signal transduction2IBA,IDAHomo_sapiens(9606)Process
GO:0045070involved_in positive regulation of viral genome replication1IDAHomo_sapiens(9606)Process
GO:0045071involved_in negative regulation of viral genome replication1IDAHomo_sapiens(9606)Process
GO:0045087involved_in innate immune response1ICHomo_sapiens(9606)Process
GO:0048024involved_in regulation of mRNA splicing, via spliceosome1TASHomo_sapiens(9606)Process
GO:0050684involved_in regulation of mRNA processing2IBA,IDAHomo_sapiens(9606)Process
GO:0106310enables protein serine kinase activity1IEAHomo_sapiens(9606)Function

Expression