Ensembl ID ENSG00000096063 Gene ID 6732 Accession 11305
Gene Symbol SRPK1 Alias SFRSK1 Full Name SRSF protein kinase 1
Position 6 : 35832966 - 35921342 Length 88377 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. Alternative splicing of this gene results in multiple transcript variants. Additional alternatively spliced transcript variants have been described for this gene, but their full length nature have not been determined.[provided by RefSeq, Jul 2010]

ENSG00000096063 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000096063 SRPK1 -0.6 7.83e-25 KIRC
ENSG00000096063 SRPK1 0.92 1.06e-38 BRCA
ENSG00000096063 SRPK1 0.85 4.97e-18 COAD
ENSG00000096063 SRPK1 1.42 1.35e-74 LUSC
ENSG00000096063 SRPK1 0.75 8.65e-13 STAD
ENSG00000096063 SRPK1 0.91 8.40e-18 UCEC
ENSG00000096063 SRPK1 1.57 7.18e-88 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000096063 SRPK1 testicular germ cell tumors 15256051
ENSG00000096063 SRPK1 cancer 16585209
ENSG00000096063 SRPK1 tumors 17091485
ENSG00000096063 SRPK1 colonic tumors 17332336
ENSG00000096063 SRPK1 breast cancer 19014521
ENSG00000096063 SRPK1 tumor 19516963
ENSG00000096063 SRPK1 cancer 19906640
ENSG00000096063 SRPK1 cancer 20938052
ENSG00000096063 SRPK1 tumor 22172722
ENSG00000096063 SRPK1 lung cancer 23071587
ENSG00000096063 SRPK1 tumors 23236423
ENSG00000096063 SRPK1 tumor 23644876
ENSG00000096063 SRPK1 prostate cancer 23935865
ENSG00000096063 SRPK1 cancer 24069033
ENSG00000096063 SRPK1 cancers 24101931
ENSG00000096063 SRPK1 tumor 24312143
ENSG00000096063 SRPK1 tumor 24550521
ENSG00000096063 SRPK1 cancer 24703948
ENSG00000096063 SRPK1 tumor 24813709
ENSG00000096063 SRPK1 breast cancer 24961466
ENSG00000096063 SRPK1 tumour 25010863
ENSG00000096063 SRPK1 breast cancer 25140042
ENSG00000096063 SRPK1 prostate cancer 25381816
ENSG00000096063 SRPK1 cancer 25548907
ENSG00000096063 SRPK1 tumor 25581376
ENSG00000096063 SRPK1 tumor 25625699
ENSG00000096063 SRPK1 breast cancer 25774502
ENSG00000096063 SRPK1 tumors 25833691
ENSG00000096063 SRPK1 ovarian cancer 25866223
ENSG00000096063 SRPK1 ovarian cancer 25967360
ENSG00000096063 SRPK1 invasive breast cancer 26087699
ENSG00000096063 SRPK1 cancers 26098145
ENSG00000096063 SRPK1 cancer 26201897
ENSG00000096063 SRPK1 AML 26244849
ENSG00000096063 SRPK1 tumor 26273588
ENSG00000096063 SRPK1 tumour 26273627
ENSG00000096063 SRPK1 tumour 26500332
ENSG00000096063 SRPK1 non-small cell lung cancer 26666824
ENSG00000096063 SRPK1 tumor 26738865
ENSG00000096063 SRPK1 colorectal cancer 26887056
ENSG00000096063 SRPK1 cancers 26887384
ENSG00000096063 SRPK1 prostate cancer 26995304
ENSG00000096063 SRPK1 tumour 27391422
ENSG00000096063 SRPK1 cancer 27662590
ENSG00000096063 SRPK1 cancers 27859253
ENSG00000096063 SRPK1 colorectal cancer 27888635
ENSG00000096063 SRPK1 cancer 28034912
ENSG00000096063 SRPK1 tumor 28108736
ENSG00000096063 SRPK1 prostate cancer 28382513
ENSG00000096063 SRPK1 tumors 28606154
ENSG00000096063 SRPK1 HNSCCs 28843252
ENSG00000096063 SRPK1 cancers 28858257
ENSG00000096063 SRPK1 gastric cancer 28977917
ENSG00000096063 SRPK1 gastric cancer 29069776
ENSG00000096063 SRPK1 cancers 29100313
ENSG00000096063 SRPK1 cancer 29138847
ENSG00000096063 SRPK1 cancer 29233683
ENSG00000096063 SRPK1 breast cancer 29262565
ENSG00000096063 SRPK1 cancers 29283381
ENSG00000096063 SRPK1 tumor 29510776
ENSG00000096063 SRPK1 colorectal cancer 29615842
ENSG00000096063 SRPK1 tumour 29693622
ENSG00000096063 SRPK1 prostate cancer 29904055
ENSG00000096063 SRPK1 colorectal cancer 30214242
ENSG00000096063 SRPK1 cancer 30535769
ENSG00000096063 SRPK1 acute myeloid leukemia (AML) 30568163
ENSG00000096063 SRPK1 gastric cancer 30633341
ENSG00000096063 SRPK1 tumor 30641926
ENSG00000096063 SRPK1 cancer 30675221
ENSG00000096063 SRPK1 tumor 31134126
ENSG00000096063 SRPK1 tumors 31151317
ENSG00000096063 SRPK1 breast cancer 31206546
ENSG00000096063 SRPK1 cancer 31225451
ENSG00000096063 SRPK1 cancer 31641093
ENSG00000096063 SRPK1 breast cancer 31666932
ENSG00000096063 SRPK1 Cancer 31861708
ENSG00000096063 SRPK1 cancers 31962201
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000096063 SRPK1 CHOL 0.032 high
ENSG00000096063 SRPK1 UCEC 0.001 high
ENSG00000096063 SRPK1 THCA 0.02 high
ENSG00000096063 SRPK1 ACC 0.0011 high
ENSG00000096063 SRPK1 LGG 0.042 high
ENSG00000096063 SRPK1 HNSC 0.035 high
ENSG00000096063 SRPK1 READ 0.00021 low
ENSG00000096063 SRPK1 KIRP 0.0082 high
ENSG00000096063 SRPK1 LUAD 0.004 high
ENSG00000096063 SRPK1 PCPG 0.021 low
ENSG00000096063 SRPK1 THYM 0.00099 low
ENSG00000096063 SRPK1 BRCA 0.01 high
ENSG00000096063 SRPK1 COAD 0.047 low
ENSG00000096063 SRPK1 OV 0.015 low
ENSG00000096063 SRPK1 KIRC 0.00063 high
ENSG00000096063 SRPK1 BLCA 0.0087 low
ENSG00000096063 SRPK1 GBM 0.036 low
ENSG00000096063 SRPK1 SKCM 0.0025 high
ENSG00000096063 SRPK1 CESC 0.00056 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000096063 SRPK1 SKCM Amp 0.992978 0.129554 0.738712 0.501362
ENSG00000096063 SRPK1 UVM Amp 1.872709 0.238074 1.140112 0.537500