Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs ncRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000089127 Gene ID 4938 Accession 8086
Symbol OAS1 Alias OIAS;IFI-4;OIASI;IMD100;E18/E16 Full Name 2'-5'-oligoadenylate synthetase 1
Status Confidence Length 27364 bases Strand Plus strand
Position 12 : 112905856 - 112933219 RNA binding domain OAS1_C
Summary This interferon-induced gene encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein plays a key role in innate cellular antiviral response, and has been implicated in other cellular processes like cell growth and apoptosis. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection, including SARS-CoV-2, and diabetes mellitus, type 1. This gene is located in a cluster of related genes on chromosome 12. [provided by RefSeq, May 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000415721 OAS1_C PF10421 2.1e-89 1
ENSP00000448790 OAS1_C PF10421 2.1e-89 1
ENSP00000475139 OAS1_C PF10421 2.1e-89 1
ENSP00000505703 OAS1_C PF10421 2.2e-89 1
ENSP00000449053 OAS1_C PF10421 2.3e-89 1
ENSP00000504942 OAS1_C PF10421 2.5e-89 1
ENSP00000504970 OAS1_C PF10421 2.7e-89 1
ENSP00000202917 OAS1_C PF10421 2.7e-89 1
ENSP00000505482 OAS1_C PF10421 2.7e-89 1
ENSP00000505572 OAS1_C PF10421 2.7e-89 1
ENSP00000506593 OAS1_C PF10421 2.8e-89 1
ENSP00000474083 OAS1_C PF10421 3e-89 1
ENSP00000388001 OAS1_C PF10421 3.2e-89 1
ENSP00000505028 OAS1_C PF10421 3.4e-66 1
ENSP00000450286 OAS1_C PF10421 2.2e-64 1
ENSP00000505090 OAS1_C PF10421 1.2e-63 1
ENSP00000505165 OAS1_C PF10421 1.3e-58 1
ENSP00000505786 OAS1_C PF10421 1.4e-58 1
ENSP00000502804 OAS1_C PF10421 7.4e-58 1
ENSP00000506580 OAS1_C PF10421 9.1e-58 1
ENSP00000506474 OAS1_C PF10421 3.7e-24 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
OAS1-220 ENST00000680189 2133 400aa ENSP00000505572
OAS1-203 ENST00000452357 3504 364aa ENSP00000415721
OAS1-202 ENST00000445409 1718 414aa ENSP00000388001
OAS1-218 ENST00000679971 1072 256aa ENSP00000505786
OAS1-232 ENST00000681831 3475 No protein -
OAS1-212 ENST00000675868 1340 356aa ENSP00000502804
OAS1-207 ENST00000550883 3939 306aa ENSP00000450286
OAS1-210 ENST00000553152 2412 384aa ENSP00000449053
OAS1-201 ENST00000202917 1631 400aa ENSP00000202917
OAS1-214 ENST00000679467 1646 405aa ENSP00000506593
OAS1-223 ENST00000680659 1682 353aa ENSP00000504942
OAS1-204 ENST00000540589 1510 403aa ENSP00000474083
OAS1-209 ENST00000552526 1425 361aa ENSP00000475139
OAS1-227 ENST00000681228 1533 371aa ENSP00000505703
OAS1-205 ENST00000549820 2370 No protein -
OAS1-216 ENST00000679767 1417 157aa ENSP00000505476
OAS1-230 ENST00000681505 1573 203aa ENSP00000505794
OAS1-225 ENST00000680934 1368 316aa ENSP00000505028
OAS1-222 ENST00000680522 1603 161aa ENSP00000506485
OAS1-233 ENST00000681934 1497 400aa ENSP00000505482
OAS1-231 ENST00000681700 1577 392aa ENSP00000506580
OAS1-219 ENST00000679987 1619 407aa ENSP00000504970
OAS1-221 ENST00000680455 1112 242aa ENSP00000505165
OAS1-208 ENST00000551241 2413 360aa ENSP00000448790
OAS1-206 ENST00000550689 1076 203aa ENSP00000448348
OAS1-217 ENST00000679841 1894 202aa ENSP00000505725
OAS1-224 ENST00000680919 1590 242aa ENSP00000506474
OAS1-215 ENST00000679494 1392 408aa ENSP00000505090
OAS1-211 ENST00000553185 665 177aa ENSP00000448001
OAS1-228 ENST00000681436 7546 No protein -
OAS1-229 ENST00000681466 766 No protein -
OAS1-213 ENST00000679413 3720 No protein -
OAS1-226 ENST00000681194 2396 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
72095gamma-Glutamyltransferase6E-4421909109
103662Diabetes Mellitus, Type 25E-923575436

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000089127homo_sapiensENSP0000037636235.953427.0742homo_sapiensENSP0000020291761.7546.5
ENSG00000089127homo_sapiensENSP0000022892822.539118.9512homo_sapiensENSP0000020291761.2551.5
ENSG00000089127homo_sapiensENSP0000025757040.661528.2101homo_sapiensENSP0000020291752.2536.25

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000089127homo_sapiensENSP0000020291795.7592.5nomascus_leucogenysENSNLEP0000003798795.7592.5
ENSG00000089127homo_sapiensENSP000002029179897.25pan_paniscusENSPPAP0000001337097.755697.0075
ENSG00000089127homo_sapiensENSP0000020291785.2583.5pongo_abeliiENSPPYP0000004478080.997679.3349
ENSG00000089127homo_sapiensENSP0000020291785.2582.25pan_troglodytesENSPTRP0000004989777.149374.4344
ENSG00000089127homo_sapiensENSP000002029178886.5gorilla_gorillaENSGGOP0000002679685.024283.5749
ENSG00000089127homo_sapiensENSP000002029173628.25sarcophilus_harrisiiENSSHAP0000004485055.81443.7985
ENSG00000089127homo_sapiensENSP0000020291764.553.75sarcophilus_harrisiiENSSHAP0000002082365.648954.7074
ENSG00000089127homo_sapiensENSP0000020291728.2520.5sarcophilus_harrisiiENSSHAP0000002347666.863948.5207
ENSG00000089127homo_sapiensENSP0000020291733.2527.25notamacropus_eugeniiENSMEUP0000001107438.662831.686
ENSG00000089127homo_sapiensENSP000002029172319choloepus_hoffmanniENSCHOP0000000029643.601936.019
ENSG00000089127homo_sapiensENSP0000020291775.565dasypus_novemcinctusENSDNOP0000001969683.425471.8232
ENSG00000089127homo_sapiensENSP0000020291754.546erinaceus_europaeusENSEEUP0000000346258.288849.1979
ENSG00000089127homo_sapiensENSP0000020291788.2582.75callithrix_jacchusENSCJAP0000002312588.2582.75
ENSG00000089127homo_sapiensENSP0000020291785.2582.25cercocebus_atysENSCATP0000003075675.442572.7876
ENSG00000089127homo_sapiensENSP000002029179590.75macaca_fascicularisENSMFAP0000001147977.868974.3852
ENSG00000089127homo_sapiensENSP0000020291794.7590.5macaca_mulattaENSMMUP0000001679377.663974.1803
ENSG00000089127homo_sapiensENSP000002029179591macaca_nemestrinaENSMNEP0000004401877.868974.5902
ENSG00000089127homo_sapiensENSP0000020291785.7582.25papio_anubisENSPANP0000000919683.252479.8544
ENSG00000089127homo_sapiensENSP000002029179591.75mandrillus_leucophaeusENSMLEP000000015229591.75
ENSG00000089127homo_sapiensENSP0000020291770.7561tursiops_truncatusENSTTRP0000000225269.533259.9509
ENSG00000089127homo_sapiensENSP000002029178068.25vulpes_vulpesENSVVUP0000001414080.200568.4211
ENSG00000089127homo_sapiensENSP0000020291725.7520.75mus_spretusMGP_SPRETEiJ_P007307463.975251.5528
ENSG00000089127homo_sapiensENSP000002029173628.75mus_spretusMGP_SPRETEiJ_P007307867.924554.2453
ENSG00000089127homo_sapiensENSP0000020291710.75equus_asinusENSEASP000050624051.769911.32743
ENSG00000089127homo_sapiensENSP0000020291781.2570.5equus_asinusENSEASP0000503877881.453670.6767
ENSG00000089127homo_sapiensENSP000002029177766capra_hircusENSCHIP0000002164278.974467.6923
ENSG00000089127homo_sapiensENSP000002029177163.5loxodonta_africanaENSLAFP0000000465883.040974.269
ENSG00000089127homo_sapiensENSP0000020291769.7558.5panthera_leoENSPLOP0000002309564.733254.2923
ENSG00000089127homo_sapiensENSP0000020291777.566.75ailuropoda_melanoleucaENSAMEP0000000912071.428661.5207
ENSG00000089127homo_sapiensENSP0000020291777.566.25bos_indicus_hybridENSBIXP0000504269379.487267.9487
ENSG00000089127homo_sapiensENSP0000020291771.7562.25oryctolagus_cuniculusENSOCUP0000004544880.167669.5531
ENSG00000089127homo_sapiensENSP0000020291778.7568.25equus_caballusENSECAP0000007366877.205966.9118
ENSG00000089127homo_sapiensENSP0000020291780.568.75canis_lupus_familiarisENSCAFP0084503037980.701868.9223
ENSG00000089127homo_sapiensENSP000002029177462.5panthera_pardusENSPPRP0000001757077.083365.1042
ENSG00000089127homo_sapiensENSP0000020291773.564.25marmota_marmota_marmotaENSMMMP0000002464279.674869.6477
ENSG00000089127homo_sapiensENSP000002029178069.75balaenoptera_musculusENSBMSP0001002529982.901672.2798
ENSG00000089127homo_sapiensENSP0000020291772.2562.5balaenoptera_musculusENSBMSP0001002556574.484564.433
ENSG00000089127homo_sapiensENSP0000020291774.560.75cavia_porcellusENSCPOP0000002181873.762460.1485
ENSG00000089127homo_sapiensENSP000002029177766.75felis_catusENSFCAP0000000029276.80866.5835
ENSG00000089127homo_sapiensENSP000002029177766.25ursus_americanusENSUAMP000000375117766.25
ENSG00000089127homo_sapiensENSP0000020291747.538monodelphis_domesticaENSMODP0000004463663.758451.0067
ENSG00000089127homo_sapiensENSP0000020291768.2556.25monodelphis_domesticaENSMODP0000000396268.765756.6751
ENSG00000089127homo_sapiensENSP000002029176352.75bison_bison_bisonENSBBBP0000002412277.538564.9231
ENSG00000089127homo_sapiensENSP000002029177867.25bison_bison_bisonENSBBBP0000000492780.205769.1517
ENSG00000089127homo_sapiensENSP0000020291731.7525.75bison_bison_bisonENSBBBP0000002018571.348357.8652
ENSG00000089127homo_sapiensENSP0000020291732.526monodon_monocerosENSMMNP0001500037673.033758.427
ENSG00000089127homo_sapiensENSP000002029173932.5monodon_monocerosENSMMNP0001501003672.558160.4651
ENSG00000089127homo_sapiensENSP0000020291733.7529.25monodon_monocerosENSMMNP0001500033278.947468.4211
ENSG00000089127homo_sapiensENSP0000020291760.7553sus_scrofaENSSSCP0000006428172.754563.4731
ENSG00000089127homo_sapiensENSP0000020291776.570.25microcebus_murinusENSMICP0000001796983.152276.3587
ENSG00000089127homo_sapiensENSP0000020291767.2559.25octodon_degusENSODEP0000001616578.885669.5015
ENSG00000089127homo_sapiensENSP0000020291758.2549.25jaculus_jaculusENSJJAP0000000288975.404563.754
ENSG00000089127homo_sapiensENSP0000020291771.562ovis_aries_rambouilletENSOARP0002002265437.93132.8912
ENSG00000089127homo_sapiensENSP0000020291757.546.75ovis_aries_rambouilletENSOARP0002002321664.425852.381
ENSG00000089127homo_sapiensENSP0000020291770.7561ovis_aries_rambouilletENSOARP0002002301280.1769.1218
ENSG00000089127homo_sapiensENSP0000020291769.559.25ovis_aries_rambouilletENSOARP0002002297278.753567.1388
ENSG00000089127homo_sapiensENSP000002029177766.25ursus_maritimusENSUMAP000000135227766.25
ENSG00000089127homo_sapiensENSP0000020291774.562ochotona_princepsENSOPRP0000001082577.002664.0827
ENSG00000089127homo_sapiensENSP0000020291775.564.5delphinapterus_leucasENSDLEP0000002830273.30162.6214
ENSG00000089127homo_sapiensENSP000002029177867.25physeter_catodonENSPCTP0000501886880.205769.1517
ENSG00000089127homo_sapiensENSP0000020291751.7541mus_caroliMGP_CAROLIEiJ_P007039269.932455.4054
ENSG00000089127homo_sapiensENSP0000020291752.2539.75mus_caroliMGP_CAROLIEiJ_P007038669.205352.649
ENSG00000089127homo_sapiensENSP000002029175543.75mus_caroliMGP_CAROLIEiJ_P007039168.535854.5171
ENSG00000089127homo_sapiensENSP000002029174135.75mus_caroliMGP_CAROLIEiJ_P007038977.725167.7725
ENSG00000089127homo_sapiensENSP000002029174135.75mus_caroliMGP_CAROLIEiJ_P007039077.725167.7725
ENSG00000089127homo_sapiensENSP0000020291773.2563mus_musculusENSMUSP0000008355579.836568.6648
ENSG00000089127homo_sapiensENSP0000020291760.2545.5mus_musculusENSMUSP0000007229765.311749.3225
ENSG00000089127homo_sapiensENSP0000020291759.545.5mus_musculusENSMUSP0000014452961.65847.1503
ENSG00000089127homo_sapiensENSP000002029176246.5mus_musculusENSMUSP0000011258468.508351.3812
ENSG00000089127homo_sapiensENSP0000020291763.2551mus_musculusENSMUSP0000005699369.505556.044
ENSG00000089127homo_sapiensENSP0000020291761.552.25mus_musculusENSMUSP0000013808865.425555.5851
ENSG00000089127homo_sapiensENSP0000020291773.7562.5mus_musculusENSMUSP0000007919880.381568.1199
ENSG00000089127homo_sapiensENSP0000020291760.2546.5mus_musculusENSMUSP0000004805466.75951.5235
ENSG00000089127homo_sapiensENSP0000020291775.564.25mustela_putorius_furoENSMPUP0000000251475.564.25
ENSG00000089127homo_sapiensENSP0000020291788.7583.5aotus_nancymaaeENSANAP0000002155889.873484.557
ENSG00000089127homo_sapiensENSP000002029178782.5saimiri_boliviensis_boliviensisENSSBOP000000395578782.5
ENSG00000089127homo_sapiensENSP0000020291794.7590chlorocebus_sabaeusENSCSAP0000001557584.598280.3571
ENSG00000089127homo_sapiensENSP000002029176051.5tupaia_belangeriENSTBEP0000001529468.965559.1954
ENSG00000089127homo_sapiensENSP000002029175444.25mesocricetus_auratusENSMAUP0000000568272.97359.7973
ENSG00000089127homo_sapiensENSP0000020291751.540.5mesocricetus_auratusENSMAUP0000000251173.571457.8571
ENSG00000089127homo_sapiensENSP0000020291730.7526.75mesocricetus_auratusENSMAUP0000002504178.343968.1529
ENSG00000089127homo_sapiensENSP0000020291733.2527.75phocoena_sinusENSPSNP0000001172975.141262.7119
ENSG00000089127homo_sapiensENSP000002029177766.25camelus_dromedariusENSCDRP0000502816078.974467.9487
ENSG00000089127homo_sapiensENSP0000020291774.565.25carlito_syrichtaENSTSYP0000000364785.386874.7851
ENSG00000089127homo_sapiensENSP0000020291759.2546rattus_norvegicusENSRNOP0000004366165.65150.9695
ENSG00000089127homo_sapiensENSP0000020291770.7560rattus_norvegicusENSRNOP0000006621279.494467.4157
ENSG00000089127homo_sapiensENSP0000020291760.7546.5rattus_norvegicusENSRNOP0000007402467.127151.3812
ENSG00000089127homo_sapiensENSP0000020291772.562rattus_norvegicusENSRNOP0000004841168.557958.6288
ENSG00000089127homo_sapiensENSP0000020291765.2556.75rattus_norvegicusENSRNOP0000004259168.865459.8945
ENSG00000089127homo_sapiensENSP0000020291760.2547.5rattus_norvegicusENSRNOP0000003213966.574652.4862
ENSG00000089127homo_sapiensENSP0000020291764.2552rattus_norvegicusENSRNOP0000007036071.587757.9387
ENSG00000089127homo_sapiensENSP0000020291769.7559rattus_norvegicusENSRNOP0000004834073.036761.7801
ENSG00000089127homo_sapiensENSP0000020291774.7566.5prolemur_simusENSPSMP0000000163682.596773.4807
ENSG00000089127homo_sapiensENSP0000020291763.2550.25microtus_ochrogasterENSMOCP0000001576769.69755.3719
ENSG00000089127homo_sapiensENSP0000020291766.7555.25sorex_araneusENSSARP0000000478766.917355.3885
ENSG00000089127homo_sapiensENSP0000020291769.7560.5peromyscus_maniculatus_bairdiiENSPEMP0000003518773.036763.3508
ENSG00000089127homo_sapiensENSP000002029176857.5peromyscus_maniculatus_bairdiiENSPEMP0000003504570.284259.4315
ENSG00000089127homo_sapiensENSP0000020291766.556.5peromyscus_maniculatus_bairdiiENSPEMP0000002137570.55759.9469
ENSG00000089127homo_sapiensENSP0000020291729.522.25peromyscus_maniculatus_bairdiiENSPEMP0000001752469.822552.6627
ENSG00000089127homo_sapiensENSP000002029176757.25peromyscus_maniculatus_bairdiiENSPEMP0000003108274.651863.7883
ENSG00000089127homo_sapiensENSP000002029177161bos_mutusENSBMUP0000002527376.139465.4156
ENSG00000089127homo_sapiensENSP0000020291761.2552mus_spicilegusENSMSIP0000003502259.610750.6083
ENSG00000089127homo_sapiensENSP0000020291757.7543mus_spicilegusENSMSIP0000003503461.645.8667
ENSG00000089127homo_sapiensENSP000002029176045.25mus_spicilegusENSMSIP0000003501762.015546.77
ENSG00000089127homo_sapiensENSP000002029176246.25mus_spicilegusENSMSIP0000003501868.508351.105
ENSG00000089127homo_sapiensENSP000002029176450.5mus_spicilegusENSMSIP0000003504070.329755.4945
ENSG00000089127homo_sapiensENSP000002029177362.75mus_spicilegusENSMSIP0000000963079.56468.3924
ENSG00000089127homo_sapiensENSP0000020291738.2530cricetulus_griseus_chok1gshdENSCGRP0000100027072.169856.6038
ENSG00000089127homo_sapiensENSP000002029175044.5cricetulus_griseus_chok1gshdENSCGRP0000100185779.051470.3557
ENSG00000089127homo_sapiensENSP000002029176455cricetulus_griseus_chok1gshdENSCGRP0000100609976.190565.4762
ENSG00000089127homo_sapiensENSP0000020291765.553.75cricetulus_griseus_chok1gshdENSCGRP0000101120664.691453.0864
ENSG00000089127homo_sapiensENSP000002029177262.75cricetulus_griseus_chok1gshdENSCGRP0000101002578.688568.5792
ENSG00000089127homo_sapiensENSP000002029176354.75cricetulus_griseus_chok1gshdENSCGRP0000101333268.664859.673
ENSG00000089127homo_sapiensENSP0000020291770.2561cricetulus_griseus_chok1gshdENSCGRP0000101648769.900560.6965
ENSG00000089127homo_sapiensENSP0000020291765.7554.5cricetulus_griseus_chok1gshdENSCGRP0000101775571.081158.9189
ENSG00000089127homo_sapiensENSP0000020291774.2563.5pteropus_vampyrusENSPVAP0000001635973.880663.1841
ENSG00000089127homo_sapiensENSP0000020291775.7565.5myotis_lucifugusENSMLUP0000001661477.89267.3522
ENSG00000089127homo_sapiensENSP0000020291767.7560.5myotis_lucifugusENSMLUP0000001436678.550770.1449
ENSG00000089127homo_sapiensENSP0000020291765.7554vombatus_ursinusENSVURP0001000499376.453562.7907
ENSG00000089127homo_sapiensENSP000002029177665rhinolophus_ferrumequinumENSRFEP0001001533578.350567.0103
ENSG00000089127homo_sapiensENSP0000020291775.2563.5neovison_visonENSNVIP0000001972975.062363.3416
ENSG00000089127homo_sapiensENSP0000020291768.558.5bos_taurusENSBTAP0000004241875.690664.6409
ENSG00000089127homo_sapiensENSP0000020291778.567.75bos_taurusENSBTAP0000001685680.719869.6658
ENSG00000089127homo_sapiensENSP0000020291771.7561.25bos_taurusENSBTAP0000000201981.534169.6023
ENSG00000089127homo_sapiensENSP0000020291775.565.25heterocephalus_glaber_femaleENSHGLP0000002283272.422162.5899
ENSG00000089127homo_sapiensENSP0000020291782.577.75rhinopithecus_bietiENSRBIP0000000031580.882476.2255
ENSG00000089127homo_sapiensENSP0000020291780.568.75canis_lupus_dingoENSCAFP0002002227280.701868.9223
ENSG00000089127homo_sapiensENSP0000020291772.2565.75sciurus_vulgarisENSSVLP0000500604775.654468.8482
ENSG00000089127homo_sapiensENSP0000020291767.2553phascolarctos_cinereusENSPCIP0000002503577.97161.4493
ENSG00000089127homo_sapiensENSP0000020291731.7526.25procavia_capensisENSPCAP0000000277234.604928.6104
ENSG00000089127homo_sapiensENSP0000020291766.7556.75nannospalax_galiliENSNGAP0000000931376.504365.043
ENSG00000089127homo_sapiensENSP0000020291773.7563nannospalax_galiliENSNGAP0000000786580.381568.6648
ENSG00000089127homo_sapiensENSP0000020291776.565.75bos_grunniensENSBGRP0000003021874.271863.835
ENSG00000089127homo_sapiensENSP0000020291716.2512.75chinchilla_lanigeraENSCLAP0000002271650.387639.5349
ENSG00000089127homo_sapiensENSP000002029177767.5cervus_hanglu_yarkandensisENSCHYP0000000020378.974469.2308
ENSG00000089127homo_sapiensENSP0000020291758.550.75catagonus_wagneriENSCWAP0000002305878.260967.893
ENSG00000089127homo_sapiensENSP000002029177766.75ictidomys_tridecemlineatusENSSTOP0000001712478.371567.9389
ENSG00000089127homo_sapiensENSP0000020291772.7564.75otolemur_garnettiiENSOGAP0000001337676.578968.1579
ENSG00000089127homo_sapiensENSP000002029178882.75cebus_imitatorENSCCAP000000034178882.75
ENSG00000089127homo_sapiensENSP000002029177767urocitellus_parryiiENSUPAP0001001066378.371568.1934
ENSG00000089127homo_sapiensENSP0000020291766.2556moschus_moschiferusENSMMSP0000002380475.284163.6364
ENSG00000089127homo_sapiensENSP0000020291777.567moschus_moschiferusENSMMSP0000002382380.103469.2506
ENSG00000089127homo_sapiensENSP0000020291793.588rhinopithecus_roxellanaENSRROP0000004219290.120584.8193
ENSG00000089127homo_sapiensENSP0000020291761.546mus_pahariMGP_PahariEiJ_P005860168.14450.9695
ENSG00000089127homo_sapiensENSP00000202917169.25mus_pahariMGP_PahariEiJ_P000995818.233610.5413
ENSG00000089127homo_sapiensENSP0000020291735.2528.75mus_pahariMGP_PahariEiJ_P005860369.80256.9307
ENSG00000089127homo_sapiensENSP0000020291758.7544.75mus_pahariMGP_PahariEiJ_P005860564.383649.0411
ENSG00000089127homo_sapiensENSP0000020291731.7516.75ciona_intestinalisENSCINP0000003509943.344722.8669
ENSG00000089127homo_sapiensENSP0000020291755.540.5callorhinchus_miliiENSCMIP0000003990851.152137.3272
ENSG00000089127homo_sapiensENSP0000020291757.7545.25laticauda_laticaudataENSLLTP0000000670958.48145.8228
ENSG00000089127homo_sapiensENSP000002029175744.5notechis_scutatusENSNSUP0000002141463.157949.3075
ENSG00000089127homo_sapiensENSP000002029175845pseudonaja_textilisENSPTXP0000002350854.588242.3529
ENSG00000089127homo_sapiensENSP0000020291744.2534.75naja_najaENSNNAP0000002444458.415845.8746
ENSG00000089127homo_sapiensENSP0000020291757.2545.75naja_najaENSNNAP0000002442964.872551.8414
ENSG00000089127homo_sapiensENSP0000020291754.7541.25naja_najaENSNNAP0000002507451.04938.4615
ENSG00000089127homo_sapiensENSP0000020291758.546podarcis_muralisENSPMRP0000002420562.566849.1979

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0001730enables 2-5-oligoadenylate synthetase activity2IBA,IDAHomo_sapiens(9606)Function
GO:0003725enables double-stranded RNA binding2IBA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1TASHomo_sapiens(9606)Function
GO:0005576located_in extracellular region1IEAHomo_sapiens(9606)Component
GO:0005634is_active_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005654is_active_in nucleoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0005737colocalizes_with cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005739located_in mitochondrion1IEAHomo_sapiens(9606)Component
GO:0005783located_in endoplasmic reticulum1IEAHomo_sapiens(9606)Component
GO:0005829is_active_in cytosol3IBA,IDA,TASHomo_sapiens(9606)Component
GO:0006006involved_in glucose metabolic process1IMPHomo_sapiens(9606)Process
GO:0009615involved_in response to virus1IDAHomo_sapiens(9606)Process
GO:0016020is_active_in membrane1IBAHomo_sapiens(9606)Component
GO:0032728involved_in positive regulation of interferon-beta production1IMPHomo_sapiens(9606)Process
GO:0032760involved_in positive regulation of tumor necrosis factor production1IMPHomo_sapiens(9606)Process
GO:0034138involved_in toll-like receptor 3 signaling pathway1IMPHomo_sapiens(9606)Process
GO:0034142involved_in toll-like receptor 4 signaling pathway1IMPHomo_sapiens(9606)Process
GO:0035458involved_in cellular response to interferon-beta1IDAHomo_sapiens(9606)Process
GO:0042593involved_in glucose homeostasis1IMPHomo_sapiens(9606)Process
GO:0042742involved_in defense response to bacterium1IMPHomo_sapiens(9606)Process
GO:0043129involved_in surfactant homeostasis1IMPHomo_sapiens(9606)Process
GO:0045071involved_in negative regulation of viral genome replication2IBA,IDAHomo_sapiens(9606)Process
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function
GO:0051607involved_in defense response to virus2IBA,IDAHomo_sapiens(9606)Process
GO:0060339involved_in negative regulation of type I interferon-mediated signaling pathway1IMPHomo_sapiens(9606)Process
GO:0060700involved_in regulation of ribonuclease activity2IBA,IDAHomo_sapiens(9606)Process
GO:0070106involved_in interleukin-27-mediated signaling pathway1IEPHomo_sapiens(9606)Process
GO:0071639involved_in positive regulation of monocyte chemotactic protein-1 production1IMPHomo_sapiens(9606)Process
GO:0071659involved_in negative regulation of IP-10 production1IMPHomo_sapiens(9606)Process
GO:0098586involved_in cellular response to virus1IEPHomo_sapiens(9606)Process
GO:0140374involved_in antiviral innate immune response2IDA,IEPHomo_sapiens(9606)Process
GO:2000342involved_in negative regulation of chemokine (C-X-C motif) ligand 2 production1IMPHomo_sapiens(9606)Process

Expression