RBP Type	Non-canonical_RBPs
Diseases	Cancer Disease
Drug	N.A.
Main interacting RNAs	mRNA
Moonlighting functions	Kinase
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000086232	Gene ID	27102	Accession	24921
Symbol	EIF2AK1	Alias	HCR;HRI;hHRI;LEMSPAD	Full Name	eukaryotic translation initiation factor 2 alpha kinase 1
Status	Confidence	Length	36929 bases	Strand	Minus strand
Position	7 : 6022247 - 6059175	RNA binding domain	N.A.
Summary	The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
EIF2AK1-201	ENST00000199389	4411	630aa	ENSP00000199389
EIF2AK1-202	ENST00000422786	782	72aa	ENSP00000392734
EIF2AK1-209	ENST00000490523	905	No protein	-
EIF2AK1-210	ENST00000495565	629	No protein	-
EIF2AK1-208	ENST00000474029	609	No protein	-
EIF2AK1-207	ENST00000470168	595	No protein	-
EIF2AK1-203	ENST00000431744	806	81aa	ENSP00000392459
EIF2AK1-206	ENST00000463213	791	No protein	-
EIF2AK1-204	ENST00000446699	573	164aa	ENSP00000397590
EIF2AK1-205	ENST00000461493	631	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
4102	Triglycerides	7.37042521352238E-5	17903299
36723	Platelet Function Tests	2.9000000E-006	-

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000086232	homo_sapiens	ENSP00000370891	28.6517	16.4794	homo_sapiens	ENSP00000199389	24.2857	13.9683
ENSG00000086232	homo_sapiens	ENSP00000307235	21.9534	13.7993	homo_sapiens	ENSP00000199389	38.8889	24.4444
ENSG00000086232	homo_sapiens	ENSP00000380675	27.1605	16.2257	homo_sapiens	ENSP00000199389	24.4444	14.6032
ENSG00000086232	homo_sapiens	ENSP00000363387	38.1232	21.4076	homo_sapiens	ENSP00000199389	20.6349	11.5873
ENSG00000086232	homo_sapiens	ENSP00000233057	35.3902	20.5082	homo_sapiens	ENSP00000199389	30.9524	17.9365
ENSG00000086232	homo_sapiens	ENSP00000262300	27.2545	17.4349	homo_sapiens	ENSP00000199389	21.5873	13.8095
ENSG00000086232	homo_sapiens	ENSP00000402084	25.2322	15.4799	homo_sapiens	ENSP00000199389	25.873	15.873
ENSG00000086232	homo_sapiens	ENSP00000263791	15.7671	9.88478	homo_sapiens	ENSP00000199389	41.2698	25.873

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000086232	homo_sapiens	ENSP00000199389	96.3492	94.9206	nomascus_leucogenys	ENSNLEP00000001273	98.8599	97.3941
ENSG00000086232	homo_sapiens	ENSP00000199389	99.6825	99.0476	pan_paniscus	ENSPPAP00000031766	99.6825	99.0476
ENSG00000086232	homo_sapiens	ENSP00000199389	98.254	96.9841	pongo_abelii	ENSPPYP00000019434	98.254	96.9841
ENSG00000086232	homo_sapiens	ENSP00000199389	98.254	97.4603	pan_troglodytes	ENSPTRP00000073939	95.6723	94.8995
ENSG00000086232	homo_sapiens	ENSP00000199389	99.5238	98.8889	pan_troglodytes	ENSPTRP00000032290	99.5238	98.8889
ENSG00000086232	homo_sapiens	ENSP00000199389	99.5238	98.5714	gorilla_gorilla	ENSGGOP00000015826	99.5238	98.5714
ENSG00000086232	homo_sapiens	ENSP00000199389	75.873	63.4921	ornithorhynchus_anatinus	ENSOANP00000004447	76.3578	63.8978
ENSG00000086232	homo_sapiens	ENSP00000199389	81.9048	69.3651	sarcophilus_harrisii	ENSSHAP00000026549	67.5393	57.199
ENSG00000086232	homo_sapiens	ENSP00000199389	77.7778	71.9048	choloepus_hoffmanni	ENSCHOP00000012294	77.7778	71.9048
ENSG00000086232	homo_sapiens	ENSP00000199389	90.6349	84.2857	dasypus_novemcinctus	ENSDNOP00000013132	90.4913	84.1521
ENSG00000086232	homo_sapiens	ENSP00000199389	59.8413	53.9683	erinaceus_europaeus	ENSEEUP00000012992	59.9364	54.0541
ENSG00000086232	homo_sapiens	ENSP00000199389	72.381	64.6032	echinops_telfairi	ENSETEP00000008242	78.3505	69.9313
ENSG00000086232	homo_sapiens	ENSP00000199389	96.6667	94.9206	callithrix_jacchus	ENSCJAP00000028357	96.6667	94.9206
ENSG00000086232	homo_sapiens	ENSP00000199389	94.9206	92.6984	cercocebus_atys	ENSCATP00000024438	90.1961	88.0845
ENSG00000086232	homo_sapiens	ENSP00000199389	96.6667	94.4444	macaca_fascicularis	ENSMFAP00000048862	96.6667	94.4444
ENSG00000086232	homo_sapiens	ENSP00000199389	96.8254	94.4444	macaca_mulatta	ENSMMUP00000056472	96.672	94.2948
ENSG00000086232	homo_sapiens	ENSP00000199389	91.9048	89.8413	macaca_nemestrina	ENSMNEP00000018383	95.7025	93.5537
ENSG00000086232	homo_sapiens	ENSP00000199389	96.8254	94.6032	papio_anubis	ENSPANP00000007974	96.672	94.4532
ENSG00000086232	homo_sapiens	ENSP00000199389	96.5079	94.2857	mandrillus_leucophaeus	ENSMLEP00000012686	96.355	94.1363
ENSG00000086232	homo_sapiens	ENSP00000199389	71.5873	65.7143	tursiops_truncatus	ENSTTRP00000004995	72.2756	66.3462
ENSG00000086232	homo_sapiens	ENSP00000199389	90.7936	83.4921	vulpes_vulpes	ENSVVUP00000020647	90.7936	83.4921
ENSG00000086232	homo_sapiens	ENSP00000199389	89.2064	81.746	mus_spretus	MGP_SPRETEiJ_P0074843	90.7916	83.1987
ENSG00000086232	homo_sapiens	ENSP00000199389	91.5873	84.9206	equus_asinus	ENSEASP00005037370	91.4422	84.7861
ENSG00000086232	homo_sapiens	ENSP00000199389	87.7778	80.1587	capra_hircus	ENSCHIP00000012566	89.3376	81.5832
ENSG00000086232	homo_sapiens	ENSP00000199389	88.8889	82.381	loxodonta_africana	ENSLAFP00000010615	88.6076	82.1203
ENSG00000086232	homo_sapiens	ENSP00000199389	90.3175	83.4921	panthera_leo	ENSPLOP00000018561	88.6293	81.9315
ENSG00000086232	homo_sapiens	ENSP00000199389	88.8889	81.746	ailuropoda_melanoleuca	ENSAMEP00000009570	88.3281	81.2303
ENSG00000086232	homo_sapiens	ENSP00000199389	88.7302	81.2698	bos_indicus_hybrid	ENSBIXP00005011642	88.4494	81.0127
ENSG00000086232	homo_sapiens	ENSP00000199389	86.1905	79.8413	oryctolagus_cuniculus	ENSOCUP00000010856	87.8641	81.3916
ENSG00000086232	homo_sapiens	ENSP00000199389	91.5873	85.0794	equus_caballus	ENSECAP00000005706	91.2975	84.8101
ENSG00000086232	homo_sapiens	ENSP00000199389	90.7936	83.6508	canis_lupus_familiaris	ENSCAFP00845014173	90.7936	83.6508
ENSG00000086232	homo_sapiens	ENSP00000199389	90.1587	83.3333	panthera_pardus	ENSPPRP00000016754	88.6115	81.9033
ENSG00000086232	homo_sapiens	ENSP00000199389	86.5079	79.8413	marmota_marmota_marmota	ENSMMMP00000007638	84.2349	77.7434
ENSG00000086232	homo_sapiens	ENSP00000199389	89.8413	83.6508	balaenoptera_musculus	ENSBMSP00010022805	89.8413	83.6508
ENSG00000086232	homo_sapiens	ENSP00000199389	81.746	75.873	cavia_porcellus	ENSCPOP00000013389	89.7213	83.2753
ENSG00000086232	homo_sapiens	ENSP00000199389	90.4762	83.4921	felis_catus	ENSFCAP00000024690	88.9236	82.0593
ENSG00000086232	homo_sapiens	ENSP00000199389	90	82.381	ursus_americanus	ENSUAMP00000031343	89.7152	82.1203
ENSG00000086232	homo_sapiens	ENSP00000199389	81.1111	68.254	monodelphis_domestica	ENSMODP00000010072	81.1111	68.254
ENSG00000086232	homo_sapiens	ENSP00000199389	83.9683	76.8254	bison_bison_bison	ENSBBBP00000017556	89.3581	81.7568
ENSG00000086232	homo_sapiens	ENSP00000199389	90	83.8095	monodon_monoceros	ENSMMNP00015005281	90	83.8095
ENSG00000086232	homo_sapiens	ENSP00000199389	89.8413	81.9048	sus_scrofa	ENSSSCP00000008113	89.4155	81.5166
ENSG00000086232	homo_sapiens	ENSP00000199389	93.6508	89.5238	microcebus_murinus	ENSMICP00000011698	93.6508	89.5238
ENSG00000086232	homo_sapiens	ENSP00000199389	87.7778	81.1111	octodon_degus	ENSODEP00000015589	87.9173	81.2401
ENSG00000086232	homo_sapiens	ENSP00000199389	78.4127	71.5873	jaculus_jaculus	ENSJJAP00000003576	84.589	77.226
ENSG00000086232	homo_sapiens	ENSP00000199389	89.6825	81.4286	ovis_aries_rambouillet	ENSOARP00020030884	89.5404	81.2995
ENSG00000086232	homo_sapiens	ENSP00000199389	86.5079	79.3651	ursus_maritimus	ENSUMAP00000011978	86.9219	79.7448
ENSG00000086232	homo_sapiens	ENSP00000199389	70.3175	64.4444	ochotona_princeps	ENSOPRP00000009661	72.0325	66.0163
ENSG00000086232	homo_sapiens	ENSP00000199389	89.0476	82.5397	delphinapterus_leucas	ENSDLEP00000028769	88.4858	82.0189
ENSG00000086232	homo_sapiens	ENSP00000199389	65.5556	59.6825	physeter_catodon	ENSPCTP00005022156	89.9782	81.9172
ENSG00000086232	homo_sapiens	ENSP00000199389	89.3651	81.9048	mus_caroli	MGP_CAROLIEiJ_P0072027	90.6602	83.0918
ENSG00000086232	homo_sapiens	ENSP00000199389	89.0476	81.746	mus_musculus	ENSMUSP00000098056	90.6301	83.1987
ENSG00000086232	homo_sapiens	ENSP00000199389	87.7778	80.4762	dipodomys_ordii	ENSDORP00000023717	89.3376	81.9063
ENSG00000086232	homo_sapiens	ENSP00000199389	75.2381	69.2064	mustela_putorius_furo	ENSMPUP00000016473	89.2655	82.1092
ENSG00000086232	homo_sapiens	ENSP00000199389	91.9048	90	aotus_nancymaae	ENSANAP00000026479	94.4535	92.4959
ENSG00000086232	homo_sapiens	ENSP00000199389	72.0635	67.3016	aotus_nancymaae	ENSANAP00000015374	87.8143	82.0116
ENSG00000086232	homo_sapiens	ENSP00000199389	96.3492	94.2857	saimiri_boliviensis_boliviensis	ENSSBOP00000019687	96.1965	94.1363
ENSG00000086232	homo_sapiens	ENSP00000199389	96.8254	94.4444	chlorocebus_sabaeus	ENSCSAP00000013750	96.672	94.2948
ENSG00000086232	homo_sapiens	ENSP00000199389	44.7619	42.5397	tupaia_belangeri	ENSTBEP00000002377	63.5135	60.3604
ENSG00000086232	homo_sapiens	ENSP00000199389	88.5714	81.5873	mesocricetus_auratus	ENSMAUP00000023106	89.7106	82.6367
ENSG00000086232	homo_sapiens	ENSP00000199389	89.0476	82.2222	phocoena_sinus	ENSPSNP00000018683	84.6154	78.1297
ENSG00000086232	homo_sapiens	ENSP00000199389	90.7936	83.9683	camelus_dromedarius	ENSCDRP00005021203	90.0787	83.3071
ENSG00000086232	homo_sapiens	ENSP00000199389	93.0159	87.9365	carlito_syrichta	ENSTSYP00000002919	93.0159	87.9365
ENSG00000086232	homo_sapiens	ENSP00000199389	84.127	78.0952	panthera_tigris_altaica	ENSPTIP00000022219	90.4437	83.959
ENSG00000086232	homo_sapiens	ENSP00000199389	88.254	80.9524	rattus_norvegicus	ENSRNOP00000075036	86.2016	79.0698
ENSG00000086232	homo_sapiens	ENSP00000199389	90.4762	86.0317	prolemur_simus	ENSPSMP00000003485	92.5325	87.987
ENSG00000086232	homo_sapiens	ENSP00000199389	87.3016	79.0476	microtus_ochrogaster	ENSMOCP00000006697	89.4309	80.9756
ENSG00000086232	homo_sapiens	ENSP00000199389	43.3333	39.6825	sorex_araneus	ENSSARP00000003759	43.5407	39.8724
ENSG00000086232	homo_sapiens	ENSP00000199389	88.254	80.4762	peromyscus_maniculatus_bairdii	ENSPEMP00000028431	89.6774	81.7742
ENSG00000086232	homo_sapiens	ENSP00000199389	84.9206	77.7778	bos_mutus	ENSBMUP00000018782	83.2037	76.2053
ENSG00000086232	homo_sapiens	ENSP00000199389	89.2064	81.9048	mus_spicilegus	ENSMSIP00000035282	90.7916	83.3603
ENSG00000086232	homo_sapiens	ENSP00000199389	88.254	80.3175	cricetulus_griseus_chok1gshd	ENSCGRP00001018461	89.1026	81.0897
ENSG00000086232	homo_sapiens	ENSP00000199389	91.4286	83.8095	pteropus_vampyrus	ENSPVAP00000015191	91.7197	84.0764
ENSG00000086232	homo_sapiens	ENSP00000199389	89.2064	81.5873	myotis_lucifugus	ENSMLUP00000003480	88.5039	80.9449
ENSG00000086232	homo_sapiens	ENSP00000199389	81.746	68.7302	vombatus_ursinus	ENSVURP00010025815	72.028	60.5594
ENSG00000086232	homo_sapiens	ENSP00000199389	81.746	68.7302	vombatus_ursinus	ENSVURP00010023084	72.028	60.5594
ENSG00000086232	homo_sapiens	ENSP00000199389	89.5238	81.9048	neovison_vison	ENSNVIP00000007876	89.3819	81.775
ENSG00000086232	homo_sapiens	ENSP00000199389	88.7302	81.2698	bos_taurus	ENSBTAP00000009691	88.4494	81.0127
ENSG00000086232	homo_sapiens	ENSP00000199389	86.9841	81.1111	heterocephalus_glaber_female	ENSHGLP00000039378	81.0651	75.5917
ENSG00000086232	homo_sapiens	ENSP00000199389	89.0476	86.1905	rhinopithecus_bieti	ENSRBIP00000012810	90.0482	87.1589
ENSG00000086232	homo_sapiens	ENSP00000199389	90.7936	83.6508	canis_lupus_dingo	ENSCAFP00020021392	90.7936	83.6508
ENSG00000086232	homo_sapiens	ENSP00000199389	91.1111	84.7619	sciurus_vulgaris	ENSSVLP00005025398	91.5471	85.1675
ENSG00000086232	homo_sapiens	ENSP00000199389	81.5873	69.2064	phascolarctos_cinereus	ENSPCIP00000041419	82.24	69.76
ENSG00000086232	homo_sapiens	ENSP00000199389	75.873	71.1111	procavia_capensis	ENSPCAP00000003898	75.9936	71.2242
ENSG00000086232	homo_sapiens	ENSP00000199389	87.1429	79.0476	nannospalax_galili	ENSNGAP00000024084	88.6914	80.4523
ENSG00000086232	homo_sapiens	ENSP00000199389	88.5714	81.1111	bos_grunniens	ENSBGRP00000040972	87.874	80.4724
ENSG00000086232	homo_sapiens	ENSP00000199389	88.5714	83.1746	chinchilla_lanigera	ENSCLAP00000011012	90.2913	84.7896
ENSG00000086232	homo_sapiens	ENSP00000199389	89.6825	81.9048	cervus_hanglu_yarkandensis	ENSCHYP00000028509	80.5991	73.6091
ENSG00000086232	homo_sapiens	ENSP00000199389	89.8413	83.3333	catagonus_wagneri	ENSCWAP00000012804	89.8413	83.3333
ENSG00000086232	homo_sapiens	ENSP00000199389	90.7936	84.2857	ictidomys_tridecemlineatus	ENSSTOP00000008324	91.8138	85.2327
ENSG00000086232	homo_sapiens	ENSP00000199389	92.0635	86.8254	otolemur_garnettii	ENSOGAP00000001008	91.9176	86.6878
ENSG00000086232	homo_sapiens	ENSP00000199389	95.2381	93.0159	cebus_imitator	ENSCCAP00000040479	89.5522	87.4627
ENSG00000086232	homo_sapiens	ENSP00000199389	91.1111	84.4444	urocitellus_parryii	ENSUPAP00010007750	91.9872	85.2564
ENSG00000086232	homo_sapiens	ENSP00000199389	88.8889	81.5873	moschus_moschiferus	ENSMMSP00000021088	89.172	81.8471
ENSG00000086232	homo_sapiens	ENSP00000199389	96.8254	94.9206	rhinopithecus_roxellana	ENSRROP00000006241	96.672	94.7702
ENSG00000086232	homo_sapiens	ENSP00000199389	89.2064	81.5873	mus_pahari	MGP_PahariEiJ_P0060243	90.6452	82.9032
ENSG00000086232	homo_sapiens	ENSP00000199389	93.3333	89.2064	propithecus_coquereli	ENSPCOP00000024151	93.3333	89.2064
ENSG00000086232	homo_sapiens	ENSP00000199389	23.1746	15.2381	drosophila_melanogaster	FBpp0304607	23.9737	15.7635
ENSG00000086232	homo_sapiens	ENSP00000199389	25.873	16.5079	ciona_intestinalis	ENSCINP00000022179	21.9381	13.9973
ENSG00000086232	homo_sapiens	ENSP00000199389	48.4127	33.9683	petromyzon_marinus	ENSPMAP00000002333	56.0662	39.3382
ENSG00000086232	homo_sapiens	ENSP00000199389	39.8413	27.4603	eptatretus_burgeri	ENSEBUP00000016089	44.5826	30.7282
ENSG00000086232	homo_sapiens	ENSP00000199389	58.5714	44.127	callorhinchus_milii	ENSCMIP00000012894	56.8567	42.8351
ENSG00000086232	homo_sapiens	ENSP00000199389	50	35.873	latimeria_chalumnae	ENSLACP00000011801	54.3103	38.9655
ENSG00000086232	homo_sapiens	ENSP00000199389	57.4603	43.0159	lepisosteus_oculatus	ENSLOCP00000010296	55.2672	41.374
ENSG00000086232	homo_sapiens	ENSP00000199389	57.3016	42.381	danio_rerio	ENSDARP00000113730	54.0419	39.9701
ENSG00000086232	homo_sapiens	ENSP00000199389	58.254	43.4921	carassius_auratus	ENSCARP00000022246	55.3545	41.3273
ENSG00000086232	homo_sapiens	ENSP00000199389	57.4603	42.8571	carassius_auratus	ENSCARP00000005961	55.5215	41.411
ENSG00000086232	homo_sapiens	ENSP00000199389	57.1429	41.5873	astyanax_mexicanus	ENSAMXP00000008019	54.6282	39.7572
ENSG00000086232	homo_sapiens	ENSP00000199389	56.1905	40	ictalurus_punctatus	ENSIPUP00000004541	54.5455	38.829
ENSG00000086232	homo_sapiens	ENSP00000199389	55.0794	41.2698	esox_lucius	ENSELUP00000018298	53.3846	40
ENSG00000086232	homo_sapiens	ENSP00000199389	56.0317	43.1746	electrophorus_electricus	ENSEEEP00000021213	54.2243	41.7819
ENSG00000086232	homo_sapiens	ENSP00000199389	55.2381	42.381	oncorhynchus_kisutch	ENSOKIP00005014159	53.1298	40.7634
ENSG00000086232	homo_sapiens	ENSP00000199389	40.7937	31.1111	oncorhynchus_kisutch	ENSOKIP00005023102	58.8101	44.8513
ENSG00000086232	homo_sapiens	ENSP00000199389	28.0952	20.9524	oncorhynchus_mykiss	ENSOMYP00000077958	55.4859	41.3793
ENSG00000086232	homo_sapiens	ENSP00000199389	55.2381	42.5397	oncorhynchus_mykiss	ENSOMYP00000048654	53.2925	41.0413
ENSG00000086232	homo_sapiens	ENSP00000199389	55.2381	42.381	salmo_salar	ENSSSAP00000001295	53.0488	40.7012
ENSG00000086232	homo_sapiens	ENSP00000199389	55.2381	40.6349	salmo_salar	ENSSSAP00000063348	53.5385	39.3846
ENSG00000086232	homo_sapiens	ENSP00000199389	54.7619	42.2222	salmo_trutta	ENSSTUP00000006827	52.5114	40.4871
ENSG00000086232	homo_sapiens	ENSP00000199389	55.0794	40.4762	salmo_trutta	ENSSTUP00000004211	53.3846	39.2308
ENSG00000086232	homo_sapiens	ENSP00000199389	53.4921	40	gadus_morhua	ENSGMOP00000035384	50.5247	37.7811
ENSG00000086232	homo_sapiens	ENSP00000199389	57.3016	43.0159	fundulus_heteroclitus	ENSFHEP00000032780	54.4495	40.8748
ENSG00000086232	homo_sapiens	ENSP00000199389	57.4603	42.2222	poecilia_reticulata	ENSPREP00000006700	54.8485	40.303
ENSG00000086232	homo_sapiens	ENSP00000199389	57.7778	41.9048	xiphophorus_maculatus	ENSXMAP00000014931	54.6547	39.6396
ENSG00000086232	homo_sapiens	ENSP00000199389	53.6508	40.7937	oryzias_latipes	ENSORLP00000004354	51.5244	39.1768
ENSG00000086232	homo_sapiens	ENSP00000199389	56.1905	41.2698	cyclopterus_lumpus	ENSCLMP00005027968	53.3133	39.1566
ENSG00000086232	homo_sapiens	ENSP00000199389	55.0794	41.746	oreochromis_niloticus	ENSONIP00000053501	51.9461	39.3713
ENSG00000086232	homo_sapiens	ENSP00000199389	57.1429	42.5397	haplochromis_burtoni	ENSHBUP00000034232	54.4629	40.5446
ENSG00000086232	homo_sapiens	ENSP00000199389	57.3016	42.381	astatotilapia_calliptera	ENSACLP00000021883	54.4495	40.2715
ENSG00000086232	homo_sapiens	ENSP00000199389	57.7778	42.0635	sparus_aurata	ENSSAUP00010034026	54.7368	39.8496
ENSG00000086232	homo_sapiens	ENSP00000199389	55.3968	40.3175	lates_calcarifer	ENSLCAP00010013019	54.2768	39.5023
ENSG00000086232	homo_sapiens	ENSP00000199389	61.5873	44.6032	xenopus_tropicalis	ENSXETP00000093154	61.4897	44.5325
ENSG00000086232	homo_sapiens	ENSP00000199389	70.6349	54.2857	chrysemys_picta_bellii	ENSCPBP00000028226	68.567	52.6965
ENSG00000086232	homo_sapiens	ENSP00000199389	62.5397	47.9365	sphenodon_punctatus	ENSSPUP00000005131	67.5815	51.801
ENSG00000086232	homo_sapiens	ENSP00000199389	69.2064	52.6984	crocodylus_porosus	ENSCPRP00005007783	66.4634	50.6098
ENSG00000086232	homo_sapiens	ENSP00000199389	60.1587	47.4603	laticauda_laticaudata	ENSLLTP00000011717	61.526	48.539
ENSG00000086232	homo_sapiens	ENSP00000199389	52.381	41.2698	notechis_scutatus	ENSNSUP00000001064	56.6038	44.5969
ENSG00000086232	homo_sapiens	ENSP00000199389	33.8095	25.5556	pseudonaja_textilis	ENSPTXP00000023257	54.6154	41.2821
ENSG00000086232	homo_sapiens	ENSP00000199389	30.9524	23.4921	pseudonaja_textilis	ENSPTXP00000023252	58.0357	44.0476
ENSG00000086232	homo_sapiens	ENSP00000199389	67.1429	51.2698	anas_platyrhynchos_platyrhynchos	ENSAPLP00000003718	65.5814	50.0775
ENSG00000086232	homo_sapiens	ENSP00000199389	63.8095	49.6825	gallus_gallus	ENSGALP00010031820	63.8095	49.6825
ENSG00000086232	homo_sapiens	ENSP00000199389	65.2381	50.7937	meleagris_gallopavo	ENSMGAP00000019795	58.8825	45.8453
ENSG00000086232	homo_sapiens	ENSP00000199389	60	45.7143	serinus_canaria	ENSSCAP00000014180	66.4323	50.6151
ENSG00000086232	homo_sapiens	ENSP00000199389	54.6032	40.9524	parus_major	ENSPMJP00000023255	59.1065	44.3299
ENSG00000086232	homo_sapiens	ENSP00000199389	62.8571	50.1587	anolis_carolinensis	ENSACAP00000012984	60	47.8788
ENSG00000086232	homo_sapiens	ENSP00000199389	56.0317	41.9048	neolamprologus_brichardi	ENSNBRP00000026881	53.811	40.2439
ENSG00000086232	homo_sapiens	ENSP00000199389	59.8413	47.3016	naja_naja	ENSNNAP00000023103	64.3345	50.8532
ENSG00000086232	homo_sapiens	ENSP00000199389	62.381	50.1587	podarcis_muralis	ENSPMRP00000035140	63.0819	50.7223
ENSG00000086232	homo_sapiens	ENSP00000199389	64.6032	49.5238	geospiza_fortis	ENSGFOP00000000365	62.8086	48.1481
ENSG00000086232	homo_sapiens	ENSP00000199389	65.873	49.5238	taeniopygia_guttata	ENSTGUP00000009087	66.4	49.92
ENSG00000086232	homo_sapiens	ENSP00000199389	57.619	42.0635	erpetoichthys_calabaricus	ENSECRP00000028606	55.9322	40.8321
ENSG00000086232	homo_sapiens	ENSP00000199389	56.9841	41.5873	kryptolebias_marmoratus	ENSKMAP00000011472	54.4765	39.7572
ENSG00000086232	homo_sapiens	ENSP00000199389	53.8095	41.9048	salvator_merianae	ENSSMRP00000025981	64.3264	50.0949
ENSG00000086232	homo_sapiens	ENSP00000199389	55.2381	42.0635	oryzias_javanicus	ENSOJAP00000006112	53.7037	40.8951
ENSG00000086232	homo_sapiens	ENSP00000199389	56.0317	42.381	amphilophus_citrinellus	ENSACIP00000003322	53.4039	40.3933
ENSG00000086232	homo_sapiens	ENSP00000199389	53.8095	40.9524	dicentrarchus_labrax	ENSDLAP00005065394	54.1534	41.2141
ENSG00000086232	homo_sapiens	ENSP00000199389	57.1429	43.1746	amphiprion_percula	ENSAPEP00000000637	54.3807	41.0876
ENSG00000086232	homo_sapiens	ENSP00000199389	55.7143	42.0635	oryzias_sinensis	ENSOSIP00000040266	53.7519	40.5819
ENSG00000086232	homo_sapiens	ENSP00000199389	58.5714	44.6032	pelodiscus_sinensis	ENSPSIP00000014981	67.5824	51.4652
ENSG00000086232	homo_sapiens	ENSP00000199389	70.7936	53.9683	gopherus_evgoodei	ENSGEVP00005009525	68.7211	52.3883
ENSG00000086232	homo_sapiens	ENSP00000199389	62.8571	47.9365	chelonoidis_abingdonii	ENSCABP00000009060	70.4626	53.7367
ENSG00000086232	homo_sapiens	ENSP00000199389	57.4603	42.2222	seriola_dumerili	ENSSDUP00000006716	54.6828	40.1813
ENSG00000086232	homo_sapiens	ENSP00000199389	56.5079	41.9048	cottoperca_gobio	ENSCGOP00000007959	53.9394	40
ENSG00000086232	homo_sapiens	ENSP00000199389	61.4286	46.1905	struthio_camelus_australis	ENSSCUP00000020781	67.8947	51.0526
ENSG00000086232	homo_sapiens	ENSP00000199389	67.3016	51.9048	anser_brachyrhynchus	ENSABRP00000014295	65.4321	50.463
ENSG00000086232	homo_sapiens	ENSP00000199389	56.3492	41.1111	gasterosteus_aculeatus	ENSGACP00000012546	53.7879	39.2424
ENSG00000086232	homo_sapiens	ENSP00000199389	56.5079	41.1111	cynoglossus_semilaevis	ENSCSEP00000001053	53.4535	38.8889
ENSG00000086232	homo_sapiens	ENSP00000199389	57.1429	41.9048	poecilia_formosa	ENSPFOP00000013733	53.973	39.5802
ENSG00000086232	homo_sapiens	ENSP00000199389	56.5079	40.9524	myripristis_murdjan	ENSMMDP00005048473	54.1033	39.2097
ENSG00000086232	homo_sapiens	ENSP00000199389	54.9206	41.2698	sander_lucioperca	ENSSLUP00000051281	48.5273	36.4656
ENSG00000086232	homo_sapiens	ENSP00000199389	66.9841	50.6349	strigops_habroptila	ENSSHBP00005005580	65.2241	49.3045
ENSG00000086232	homo_sapiens	ENSP00000199389	57.3016	43.1746	amphiprion_ocellaris	ENSAOCP00000022847	54.5317	41.0876
ENSG00000086232	homo_sapiens	ENSP00000199389	70.4762	54.127	terrapene_carolina_triunguis	ENSTMTP00000023935	68.4129	52.5424
ENSG00000086232	homo_sapiens	ENSP00000199389	55.0794	40.1587	hucho_hucho	ENSHHUP00000015937	53.2209	38.8037
ENSG00000086232	homo_sapiens	ENSP00000199389	16.0317	12.2222	hucho_hucho	ENSHHUP00000069502	45.4955	34.6847
ENSG00000086232	homo_sapiens	ENSP00000199389	57.619	42.5397	betta_splendens	ENSBSLP00000045316	55.0835	40.6677
ENSG00000086232	homo_sapiens	ENSP00000199389	57.619	43.0159	pygocentrus_nattereri	ENSPNAP00000002987	54.3413	40.5689
ENSG00000086232	homo_sapiens	ENSP00000199389	57.9365	43.4921	anabas_testudineus	ENSATEP00000018950	53.9143	40.4727
ENSG00000086232	homo_sapiens	ENSP00000199389	24.9206	15.5556	ciona_savignyi	ENSCSAVP00000010266	28.702	17.9159
ENSG00000086232	homo_sapiens	ENSP00000199389	57.4603	42.381	seriola_lalandi_dorsalis	ENSSLDP00000004803	54.6828	40.3323
ENSG00000086232	homo_sapiens	ENSP00000199389	55.873	41.9048	labrus_bergylta	ENSLBEP00000012657	53.092	39.819
ENSG00000086232	homo_sapiens	ENSP00000199389	57.1429	42.6984	pundamilia_nyererei	ENSPNYP00000026206	54.878	41.0061
ENSG00000086232	homo_sapiens	ENSP00000199389	53.8095	40.1587	mastacembelus_armatus	ENSMAMP00000010643	52.3957	39.1036
ENSG00000086232	homo_sapiens	ENSP00000199389	57.1429	43.1746	stegastes_partitus	ENSSPAP00000023016	54.0541	40.8408
ENSG00000086232	homo_sapiens	ENSP00000199389	41.9048	30.4762	oncorhynchus_tshawytscha	ENSOTSP00005006061	48.4404	35.2294
ENSG00000086232	homo_sapiens	ENSP00000199389	55.0794	42.5397	oncorhynchus_tshawytscha	ENSOTSP00005059873	53.0581	40.9786
ENSG00000086232	homo_sapiens	ENSP00000199389	56.9841	42.8571	acanthochromis_polyacanthus	ENSAPOP00000002134	54.2296	40.7855
ENSG00000086232	homo_sapiens	ENSP00000199389	66.9841	50.9524	aquila_chrysaetos_chrysaetos	ENSACCP00020012978	66.5615	50.6309
ENSG00000086232	homo_sapiens	ENSP00000199389	55.3968	42.2222	nothobranchius_furzeri	ENSNFUP00015028986	54.3614	41.433
ENSG00000086232	homo_sapiens	ENSP00000199389	57.4603	40.7937	cyprinodon_variegatus	ENSCVAP00000030328	55.3517	39.2966
ENSG00000086232	homo_sapiens	ENSP00000199389	52.2222	39.3651	denticeps_clupeoides	ENSDCDP00000026642	53.1502	40.0646
ENSG00000086232	homo_sapiens	ENSP00000199389	55.0794	42.6984	larimichthys_crocea	ENSLCRP00005002912	53.7985	41.7054
ENSG00000086232	homo_sapiens	ENSP00000199389	57.619	42.2222	takifugu_rubripes	ENSTRUP00000042969	54.7511	40.1207
ENSG00000086232	homo_sapiens	ENSP00000199389	66.0317	50.4762	ficedula_albicollis	ENSFALP00000014590	64.5963	49.3789
ENSG00000086232	homo_sapiens	ENSP00000199389	47.3016	37.3016	hippocampus_comes	ENSHCOP00000011215	58.5462	46.169
ENSG00000086232	homo_sapiens	ENSP00000199389	58.254	43.6508	cyprinus_carpio_carpio	ENSCCRP00000125216	55.3545	41.4781
ENSG00000086232	homo_sapiens	ENSP00000199389	58.4127	43.8095	cyprinus_carpio_carpio	ENSCCRP00000172471	55.5053	41.629
ENSG00000086232	homo_sapiens	ENSP00000199389	66.3492	51.9048	coturnix_japonica	ENSCJPP00005016423	65.7233	51.4151
ENSG00000086232	homo_sapiens	ENSP00000199389	57.1429	41.9048	poecilia_latipinna	ENSPLAP00000009027	54.0541	39.6396
ENSG00000086232	homo_sapiens	ENSP00000199389	36.3492	25.3968	sinocyclocheilus_grahami	ENSSGRP00000002094	50.5519	35.3201
ENSG00000086232	homo_sapiens	ENSP00000199389	47.4603	33.6508	sinocyclocheilus_grahami	ENSSGRP00000060881	52.0906	36.9338
ENSG00000086232	homo_sapiens	ENSP00000199389	57.3016	42.381	sinocyclocheilus_grahami	ENSSGRP00000014175	54.5317	40.3323
ENSG00000086232	homo_sapiens	ENSP00000199389	57.3016	42.381	maylandia_zebra	ENSMZEP00005011702	54.4495	40.2715
ENSG00000086232	homo_sapiens	ENSP00000199389	53.6508	40.3175	tetraodon_nigroviridis	ENSTNIP00000015855	59.0909	44.4056
ENSG00000086232	homo_sapiens	ENSP00000199389	20.7937	16.3492	paramormyrops_kingsleyae	ENSPKIP00000025665	63.9024	50.2439
ENSG00000086232	homo_sapiens	ENSP00000199389	33.8095	24.7619	paramormyrops_kingsleyae	ENSPKIP00000022257	46.7105	34.2105
ENSG00000086232	homo_sapiens	ENSP00000199389	33.8095	24.7619	paramormyrops_kingsleyae	ENSPKIP00000016272	46.7105	34.2105
ENSG00000086232	homo_sapiens	ENSP00000199389	57.3016	44.127	scleropages_formosus	ENSSFOP00015034740	55.796	42.9675
ENSG00000086232	homo_sapiens	ENSP00000199389	61.5873	45.5556	leptobrachium_leishanense	ENSLLEP00000027695	60.2484	44.5652
ENSG00000086232	homo_sapiens	ENSP00000199389	54.2857	41.5873	scophthalmus_maximus	ENSSMAP00000016704	50.7418	38.8724
ENSG00000086232	homo_sapiens	ENSP00000199389	55.2381	42.2222	oryzias_melastigma	ENSOMEP00000025238	53.7037	41.0494

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0002526	involved_in acute inflammatory response	1	IEA	Homo_sapiens(9606)	Process
GO:0004694	enables eukaryotic translation initiation factor 2alpha kinase activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005524	enables ATP binding	1	IEA	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	1	IBA	Homo_sapiens(9606)	Component
GO:0005737	is_active_in cytoplasm	1	IBA	Homo_sapiens(9606)	Component
GO:0006468	involved_in protein phosphorylation	1	IBA	Homo_sapiens(9606)	Process
GO:0006909	involved_in phagocytosis	1	IEA	Homo_sapiens(9606)	Process
GO:0008285	involved_in negative regulation of cell population proliferation	1	IEA	Homo_sapiens(9606)	Process
GO:0010998	involved_in regulation of translational initiation by eIF2 alpha phosphorylation	1	IEA	Homo_sapiens(9606)	Process
GO:0010999	involved_in regulation of eIF2 alpha phosphorylation by heme	1	IEA	Homo_sapiens(9606)	Process
GO:0020037	enables heme binding	1	ISS	Homo_sapiens(9606)	Function
GO:0030225	involved_in macrophage differentiation	1	IEA	Homo_sapiens(9606)	Process
GO:0042803	enables protein homodimerization activity	1	ISS	Homo_sapiens(9606)	Function
GO:0045993	involved_in negative regulation of translational initiation by iron	1	NAS	Homo_sapiens(9606)	Process
GO:0046501	involved_in protoporphyrinogen IX metabolic process	1	IEA	Homo_sapiens(9606)	Process
GO:0046777	involved_in protein autophosphorylation	1	ISS	Homo_sapiens(9606)	Process
GO:0046986	involved_in negative regulation of hemoglobin biosynthetic process	1	ISS	Homo_sapiens(9606)	Process
GO:0051649	involved_in establishment of localization in cell	1	IEA	Homo_sapiens(9606)	Process
GO:0060586	involved_in multicellular organismal-level iron ion homeostasis	1	IEA	Homo_sapiens(9606)	Process
GO:0106310	enables protein serine kinase activity	1	IEA	Homo_sapiens(9606)	Function
GO:0140467	involved_in integrated stress response signaling	1	IDA	Homo_sapiens(9606)	Process
GO:0140468	involved_in HRI-mediated signaling	1	IDA	Homo_sapiens(9606)	Process
GO:1990641	involved_in response to iron ion starvation	1	IDA	Homo_sapiens(9606)	Process