Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerSARS-COV-OC43FlavivirusesSARS-COV-2SINVDengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucleP-body
BulkPerturb-seq DataSet_01_374 DataSet_01_79

Description

Ensembl ID ENSG00000073792 Gene ID 10644 Accession 28867
Symbol IGF2BP2 Alias IMP2;IMP-2;VICKZ2 Full Name insulin like growth factor 2 mRNA binding protein 2
Status Confidence Length 181913 bases Strand Minus strand
Position 3 : 185643130 - 185825042 RNA binding domain KH_1 , RRM_1
Summary This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes. [provided by RefSeq, Sep 2016]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000320204 RRM_1 PF00076 1.3e-16 1
ENSP00000320204 RRM_1 PF00076 1.3e-16 2
ENSP00000320204 KH_1 PF00013 5.1e-54 3
ENSP00000320204 KH_1 PF00013 5.1e-54 4
ENSP00000320204 KH_1 PF00013 5.1e-54 5
ENSP00000320204 KH_1 PF00013 5.1e-54 6
ENSP00000371634 RRM_1 PF00076 1.7e-16 1
ENSP00000371634 RRM_1 PF00076 1.7e-16 2
ENSP00000371634 KH_1 PF00013 7.9e-54 3
ENSP00000371634 KH_1 PF00013 7.9e-54 4
ENSP00000371634 KH_1 PF00013 7.9e-54 5
ENSP00000371634 KH_1 PF00013 7.9e-54 6
ENSP00000410242 RRM_1 PF00076 1.3e-15 1
ENSP00000410242 RRM_1 PF00076 1.3e-15 2
ENSP00000410242 KH_1 PF00013 8.7e-54 3
ENSP00000410242 KH_1 PF00013 8.7e-54 4
ENSP00000410242 KH_1 PF00013 8.7e-54 5
ENSP00000410242 KH_1 PF00013 8.7e-54 6
ENSP00000413787 RRM_1 PF00076 8.1e-06 1
ENSP00000413787 KH_1 PF00013 4.2e-54 2
ENSP00000413787 KH_1 PF00013 4.2e-54 3
ENSP00000413787 KH_1 PF00013 4.2e-54 4
ENSP00000413787 KH_1 PF00013 4.2e-54 5

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
36510377 Long non-coding RNA HOXC-AS1 exerts its oncogenic effects in esophageal squamous cell carcinoma by interaction with IGF2BP2 to stabilize SIRT1 expression. Zhengwu Yang 2023-01-01 Journal of clinical laboratory analysis
35293050 Insulin-like growth factor 2 mRNA-binding protein 2-regulated alternative splicing of nuclear factor 1 C-type causes excessive granulosa cell proliferation in polycystic ovary syndrome. Feiyan Zhao 2022-04-01 Cell proliferation
35876041 Circular RNA circ-TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA. Xiaojuan Pan 2022-07-01 Clinical and translational medicine
35036870 An adipose lncRAP2-Igf2bp2 complex enhances adipogenesis and energy expenditure by stabilizing target mRNAs. R Juan Alvarez-Dominguez 2022-01-21 iScience
34518440 lncRNA HCG11 suppresses human osteosarcoma growth through upregulating p27 Kip1. Jie Gu 2021-09-13 Aging
37310201 Implications of LncRNAs and CircRNAs in psoriasis: a review. Rongcan Shi 2023-01-01 RNA biology
34532127 Bioinformatical identification of key genes regulated by IGF2BP2-mediated RNA N6-methyladenosine and prediction of prognosis in hepatocellular carcinoma. Qiang Wei 2021-08-01 Journal of gastrointestinal oncology
31796082 Epigenomic dysregulation-mediated alterations of key biological pathways and tumor immune evasion are hallmarks of gingivo-buccal oral cancer. Debodipta Das 2019-12-03 Clinical epigenetics
32329795 Influence of IGF2BP2, HMG20A, and HNF1B genetic polymorphisms on the susceptibility to Type 2 diabetes mellitus in Chinese Han population. Ting Huang 2020-05-29 Bioscience reports
37543219 CircCDK1 blocking IGF2BP2-mediated m6A modification of CPPED1 promotes laryngeal squamous cell carcinoma metastasis via the PI3K/AKT signal pathway. Jinling Li 2023-08-03 Gene
36289466 Liver-specific lncRNA FAM99A may be a tumor suppressor and promising prognostic biomarker in hepatocellular carcinoma. Meile Mo 2022-10-26 BMC cancer
37443790 Integration of Transcriptome and MicroRNA Profile Analysis of iMSCs Defines Their Rejuvenated State and Conveys Them into a Novel Resource for Cell Therapy in Osteoarthritis. Vasileios Konteles 2023-06-30 Cells
34380038 Actinin BioID reveals sarcomere crosstalk with oxidative metabolism through interactions with IGF2BP2. A Feria Ladha 2021-08-10 Cell reports
35038236 Comment on: The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ. S Hanna Schymik 2022-03-01 Advanced science (Weinheim, Baden-Wurttemberg, Germany)
35299748 Upregulation of IGF2BP2 Promotes Oral Squamous Cell Carcinoma Progression That Is Related to Cell Proliferation, Metastasis and Tumor-Infiltrating Immune Cells. Lijie Zhou 2022-01-01 Frontiers in oncology
31619685 N6-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis. Ri-Xin Chen 2019-10-16 Nature communications
29736175 The Roles of Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 in Cancer and Cancer Stem Cells. Junguo Cao 2018-01-01 Stem cells international

Transcripts

Name Transcript ID bp Protein Translation ID
IGF2BP2-202 ENST00000382199 4283 599aa ENSP00000371634
IGF2BP2-204 ENST00000457616 3426 605aa ENSP00000410242
IGF2BP2-201 ENST00000346192 3291 556aa ENSP00000320204
IGF2BP2-206 ENST00000464166 380 No protein -
IGF2BP2-210 ENST00000494906 918 No protein -
IGF2BP2-211 ENST00000496495 472 No protein -
IGF2BP2-205 ENST00000461957 509 No protein -
IGF2BP2-209 ENST00000493302 358 No protein -
IGF2BP2-208 ENST00000466476 469 No protein -
IGF2BP2-207 ENST00000466214 138 No protein -
IGF2BP2-203 ENST00000421047 1711 536aa ENSP00000413787

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
11806Life Expectancy4.00831229478982E-517903295
11822Life Expectancy7.30888620574799E-517903295
15348Heart Failure8.8011249E-005-
26770Blood Pressure9.0190000E-005-
38512Platelet Function Tests1.7248600E-005-
61245Diabetes Mellitus, Type 22E-917463246
61288Diabetes Mellitus, Type 29E-1617463248
61305Diabetes Mellitus, Type 29E-1617463249
62214Diabetes Mellitus, Type 21E-721573907
66125Diabetes Mellitus, Type 21E-619401414
68461Glucose6E-722581228
68462Body Mass Index6E-722581228
76685Diabetes Mellitus, Type 23E-922693455
86957Diabetes Mellitus, Type 22E-920581827
87997Diabetes Mellitus, Type 25E-623300278
88461Diabetes Mellitus, Type 24E-723300278
88505Diabetes Mellitus, Type 24E-923300278
88567Diabetes Mellitus, Type 22E-1323300278
88611Diabetes Mellitus, Type 22E-1923300278
91682Diabetes Mellitus, Type 21E-918711366
93935Diabetes Mellitus, Type 21E-1724509480
94406Diabetes Mellitus, Type 23E-1427189021
97038Diabetes Mellitus, Type 28E-818372903
99756Diabetes Mellitus, Type 22E-2426818947
103873Diabetes Mellitus, Type 25E-1423945395
104672Diabetes, Gestational2E-722233651

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000073792homo_sapiensENSP0000029034181.282567.7643homo_sapiensENSP0000037163478.297265.2755
ENSG00000073792homo_sapiensENSP0000041719639.20622.3325homo_sapiensENSP0000037163426.377315.025
ENSG00000073792homo_sapiensENSP0000026325727.235814.2276homo_sapiensENSP0000037163422.370611.6861
ENSG00000073792homo_sapiensENSP0000050579640.700823.4501homo_sapiensENSP0000037163425.208714.5242
ENSG00000073792homo_sapiensENSP0000036543931.896617.4569homo_sapiensENSP0000037163424.707813.5225
ENSG00000073792homo_sapiensENSP0000044876244.475124.8619homo_sapiensENSP0000037163426.878115.025
ENSG00000073792homo_sapiensENSP0000035980431.366517.236homo_sapiensENSP0000037163433.722918.5309
ENSG00000073792homo_sapiensENSP0000025872979.447365.8031homo_sapiensENSP0000037163476.794763.606
ENSG00000073792homo_sapiensENSP0000031817734.96518.8811homo_sapiensENSP0000037163433.38918.0301
ENSG00000073792homo_sapiensENSP0000030555643.539325.5618homo_sapiensENSP0000037163425.876515.192
ENSG00000073792homo_sapiensENSP0000043887527.416214.9901homo_sapiensENSP0000037163423.205312.6878
ENSG00000073792homo_sapiensENSP0000047114628.915716.0643homo_sapiensENSP0000037163436.060120.0334

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000073792homo_sapiensENSP0000037163486.811486.6444nomascus_leucogenysENSNLEP0000000792799.616999.4253
ENSG00000073792homo_sapiensENSP0000037163489.983389.9833pan_paniscusENSPPAP0000002281898.899198.8991
ENSG00000073792homo_sapiensENSP0000037163499.499299.3322pongo_abeliiENSPPYP0000004257398.512498.3471
ENSG00000073792homo_sapiensENSP00000371634100100pan_troglodytesENSPTRP0000007105099.008399.0083
ENSG00000073792homo_sapiensENSP0000037163489.983389.9833gorilla_gorillaENSGGOP0000003744098.899198.8991
ENSG00000073792homo_sapiensENSP0000037163493.656187.6461ornithorhynchus_anatinusENSOANP0000000736667.753663.4058
ENSG00000073792homo_sapiensENSP0000037163478.631170.9516sarcophilus_harrisiiENSSHAP0000001542882.342774.3007
ENSG00000073792homo_sapiensENSP0000037163447.412446.5776choloepus_hoffmanniENSCHOP0000000884371.898770.6329
ENSG00000073792homo_sapiensENSP0000037163485.141983.6394dasypus_novemcinctusENSDNOP0000001042095.864794.1729
ENSG00000073792homo_sapiensENSP0000037163471.118569.616erinaceus_europaeusENSEEUP0000000882679.035277.3655
ENSG00000073792homo_sapiensENSP0000037163465.776364.4407echinops_telfairiENSETEP0000000984866.218564.8739
ENSG00000073792homo_sapiensENSP0000037163496.99595.3255callithrix_jacchusENSCJAP0000002719295.716694.0692
ENSG00000073792homo_sapiensENSP0000037163499.833199.6661cercocebus_atysENSCATP0000002593598.84398.6777
ENSG00000073792homo_sapiensENSP0000037163499.833199.6661macaca_fascicularisENSMFAP0000004456798.84398.6777
ENSG00000073792homo_sapiensENSP0000037163492.821492.6544macaca_mulattaENSMMUP0000003083010099.8201
ENSG00000073792homo_sapiensENSP0000037163499.666199.4992macaca_nemestrinaENSMNEP0000003909698.677798.5124
ENSG00000073792homo_sapiensENSP0000037163499.833199.6661papio_anubisENSPANP0000001054798.84398.6777
ENSG00000073792homo_sapiensENSP0000037163489.816489.6494mandrillus_leucophaeusENSMLEP0000003054598.715698.5321
ENSG00000073792homo_sapiensENSP0000037163492.821491.9866tursiops_truncatusENSTTRP0000000780295.862195
ENSG00000073792homo_sapiensENSP0000037163487.81386.9783vulpes_vulpesENSVVUP0000001711685.251284.4408
ENSG00000073792homo_sapiensENSP0000037163496.82894.6578mus_spretusMGP_SPRETEiJ_P004289697.97395.777
ENSG00000073792homo_sapiensENSP0000037163498.497597.8297equus_asinusENSEASP0000502013197.520796.8595
ENSG00000073792homo_sapiensENSP0000037163498.831498.4975capra_hircusENSCHIP0000001407598.831498.4975
ENSG00000073792homo_sapiensENSP0000037163485.809785.3088loxodonta_africanaENSLAFP0000001438998.846298.2692
ENSG00000073792homo_sapiensENSP0000037163499.165398.4975panthera_leoENSPLOP0000000743298.181897.5207
ENSG00000073792homo_sapiensENSP0000037163488.313986.3105ailuropoda_melanoleucaENSAMEP0000003153677.56675.8064
ENSG00000073792homo_sapiensENSP0000037163498.998398.4975bos_indicus_hybridENSBIXP0000502019498.016597.5207
ENSG00000073792homo_sapiensENSP0000037163498.998398.4975oryctolagus_cuniculusENSOCUP0000004372787.077886.6373
ENSG00000073792homo_sapiensENSP0000037163498.497597.8297equus_caballusENSECAP0000006421692.913492.2835
ENSG00000073792homo_sapiensENSP0000037163484.97580.8013canis_lupus_familiarisENSCAFP0084502637255.206152.4946
ENSG00000073792homo_sapiensENSP0000037163499.165398.4975panthera_pardusENSPPRP0000000940398.181897.5207
ENSG00000073792homo_sapiensENSP0000037163487.9887.3122marmota_marmota_marmotaENSMMMP0000000974289.020388.3446
ENSG00000073792homo_sapiensENSP0000037163499.165398.4975balaenoptera_musculusENSBMSP0001001165998.181897.5207
ENSG00000073792homo_sapiensENSP0000037163488.814788.3139cavia_porcellusENSCPOP0000000492798.701398.1447
ENSG00000073792homo_sapiensENSP0000037163499.165398.4975felis_catusENSFCAP0000004020898.181897.5207
ENSG00000073792homo_sapiensENSP0000037163459.098557.0952ursus_americanusENSUAMP0000000229287.841284.8635
ENSG00000073792homo_sapiensENSP0000037163477.796370.1169monodelphis_domesticaENSMODP0000000343480.344872.4138
ENSG00000073792homo_sapiensENSP0000037163498.831498.3306bison_bison_bisonENSBBBP0000002539097.851297.3554
ENSG00000073792homo_sapiensENSP0000037163499.165398.4975monodon_monocerosENSMMNP0001500379198.181897.5207
ENSG00000073792homo_sapiensENSP0000037163499.165398.6644sus_scrofaENSSSCP0000002830798.181897.686
ENSG00000073792homo_sapiensENSP0000037163499.499298.9983microcebus_murinusENSMICP0000005114698.512498.0165
ENSG00000073792homo_sapiensENSP0000037163486.978385.6427microcebus_murinusENSMICP0000002558196.481595
ENSG00000073792homo_sapiensENSP0000037163498.664497.6628octodon_degusENSODEP0000000156598.597.5
ENSG00000073792homo_sapiensENSP0000037163496.99595.9933jaculus_jaculusENSJJAP0000001298698.141997.1284
ENSG00000073792homo_sapiensENSP0000037163498.664498.3306ovis_aries_rambouilletENSOARP0002000168597.68697.3554
ENSG00000073792homo_sapiensENSP0000037163489.315587.6461ursus_maritimusENSUMAP0000000628294.690392.9204
ENSG00000073792homo_sapiensENSP0000037163472.287170.9516ochotona_princepsENSOPRP0000000270983.429781.8882
ENSG00000073792homo_sapiensENSP0000037163499.165398.4975delphinapterus_leucasENSDLEP0000001138799.165398.4975
ENSG00000073792homo_sapiensENSP0000037163499.332298.6644physeter_catodonENSPCTP0000501254798.347197.686
ENSG00000073792homo_sapiensENSP0000037163496.661194.4908mus_caroliMGP_CAROLIEiJ_P004103797.804195.6081
ENSG00000073792homo_sapiensENSP0000037163496.82894.6578mus_musculusENSMUSP0000009762997.97395.777
ENSG00000073792homo_sapiensENSP0000037163483.639482.4708dipodomys_ordiiENSDORP0000000083398.428397.053
ENSG00000073792homo_sapiensENSP0000037163475.292270.1169mustela_putorius_furoENSMPUP0000000772784.456978.6517
ENSG00000073792homo_sapiensENSP0000037163482.804782.3038mustela_putorius_furoENSMPUP0000000311999.00298.4032
ENSG00000073792homo_sapiensENSP0000037163499.833199.6661aotus_nancymaaeENSANAP0000002790898.84398.6777
ENSG00000073792homo_sapiensENSP0000037163486.644485.9766saimiri_boliviensis_boliviensisENSSBOP0000000941899.425398.659
ENSG00000073792homo_sapiensENSP0000037163445.742945.2421vicugna_pacosENSVPAP0000001118090.131689.1447
ENSG00000073792homo_sapiensENSP0000037163499.666199.3322chlorocebus_sabaeusENSCSAP0000001015399.666199.3322
ENSG00000073792homo_sapiensENSP0000037163463.439162.2705tupaia_belangeriENSTBEP0000000586280.679479.1932
ENSG00000073792homo_sapiensENSP0000037163496.160393.6561mesocricetus_auratusENSMAUP0000000636897.297394.7635
ENSG00000073792homo_sapiensENSP0000037163499.165398.6644phocoena_sinusENSPSNP0000000688094.736894.2584
ENSG00000073792homo_sapiensENSP0000037163498.831498.3306camelus_dromedariusENSCDRP0000500630197.851297.3554
ENSG00000073792homo_sapiensENSP0000037163486.978385.8097carlito_syrichtaENSTSYP0000000309697.201595.8955
ENSG00000073792homo_sapiensENSP0000037163486.811485.6427panthera_tigris_altaicaENSPTIP0000001414097.014995.709
ENSG00000073792homo_sapiensENSP0000037163496.82894.9917rattus_norvegicusENSRNOP0000003757897.97396.1149
ENSG00000073792homo_sapiensENSP0000037163486.143685.6427prolemur_simusENSPSMP0000002735699.42298.8439
ENSG00000073792homo_sapiensENSP0000037163497.662895.8264microtus_ochrogasterENSMOCP0000002189197.662895.8264
ENSG00000073792homo_sapiensENSP0000037163444.574343.9065sorex_araneusENSSARP0000001265478.761177.5811
ENSG00000073792homo_sapiensENSP0000037163498.831498.3306bos_mutusENSBMUP0000001373197.851297.3554
ENSG00000073792homo_sapiensENSP0000037163496.661194.4908mus_spicilegusENSMSIP0000001159897.804195.6081
ENSG00000073792homo_sapiensENSP0000037163497.328994.6578cricetulus_griseus_chok1gshdENSCGRP0000102017797.491694.8161
ENSG00000073792homo_sapiensENSP0000037163494.824794.1569pteropus_vampyrusENSPVAP0000001083794.824794.1569
ENSG00000073792homo_sapiensENSP0000037163486.644485.6427myotis_lucifugusENSMLUP0000000239797.556496.4286
ENSG00000073792homo_sapiensENSP0000037163492.320585.3088vombatus_ursinusENSVURP0001000096492.166785.1667
ENSG00000073792homo_sapiensENSP0000037163492.320591.8197rhinolophus_ferrumequinumENSRFEP0001001893999.460498.9209
ENSG00000073792homo_sapiensENSP0000037163496.82896.1603neovison_visonENSNVIP0000002531897.315496.6443
ENSG00000073792homo_sapiensENSP0000037163498.998398.4975bos_taurusENSBTAP0000003589798.998398.4975
ENSG00000073792homo_sapiensENSP0000037163498.998397.9967heterocephalus_glaber_femaleENSHGLP0000005782698.998397.9967
ENSG00000073792homo_sapiensENSP0000037163486.477586.3105rhinopithecus_bietiENSRBIP0000004296899.807399.6146
ENSG00000073792homo_sapiensENSP0000037163482.303880.1336canis_lupus_dingoENSCAFP0002000672381.487679.3388
ENSG00000073792homo_sapiensENSP0000037163469.949967.9466sciurus_vulgarisENSSVLP0000501723392.904790.2439
ENSG00000073792homo_sapiensENSP0000037163499.332298.8314sciurus_vulgarisENSSVLP0000501364398.347197.8512
ENSG00000073792homo_sapiensENSP0000037163491.151984.4741phascolarctos_cinereusENSPCIP0000003189691.457384.7571
ENSG00000073792homo_sapiensENSP0000037163476.627775.9599procavia_capensisENSPCAP0000001412286.116385.3659
ENSG00000073792homo_sapiensENSP0000037163484.80883.1386nannospalax_galiliENSNGAP0000001025894.599692.7374
ENSG00000073792homo_sapiensENSP0000037163498.831498.3306bos_grunniensENSBGRP0000000433097.851297.3554
ENSG00000073792homo_sapiensENSP0000037163488.647788.3139chinchilla_lanigeraENSCLAP0000002163798.515898.1447
ENSG00000073792homo_sapiensENSP0000037163498.831498.1636cervus_hanglu_yarkandensisENSCHYP0000000843097.851297.1901
ENSG00000073792homo_sapiensENSP0000037163499.332298.8314catagonus_wagneriENSCWAP0000002429498.347197.8512
ENSG00000073792homo_sapiensENSP0000037163499.332298.6644ictidomys_tridecemlineatusENSSTOP0000001693999.332298.6644
ENSG00000073792homo_sapiensENSP0000037163487.81387.1452otolemur_garnettiiENSOGAP0000000946998.872298.1203
ENSG00000073792homo_sapiensENSP0000037163499.833199.4992cebus_imitatorENSCCAP0000003378398.84398.5124
ENSG00000073792homo_sapiensENSP0000037163498.163697.4958urocitellus_parryiiENSUPAP0001000242899.156898.4823
ENSG00000073792homo_sapiensENSP0000037163498.998398.4975moschus_moschiferusENSMMSP0000001311898.016597.5207
ENSG00000073792homo_sapiensENSP0000037163489.816489.6494rhinopithecus_roxellanaENSRROP0000002243588.925688.7603
ENSG00000073792homo_sapiensENSP0000037163490.150388.4808mus_pahariMGP_PahariEiJ_P002841097.472995.6679
ENSG00000073792homo_sapiensENSP0000037163499.165398.6644propithecus_coquereliENSPCOP0000002873598.181897.686
ENSG00000073792homo_sapiensENSP0000037163419.53268.68114caenorhabditis_elegansY119D3B.17.227.083312.037
ENSG00000073792homo_sapiensENSP0000037163414.69128.34725caenorhabditis_elegansY59A8B.10d.121.103111.9904
ENSG00000073792homo_sapiensENSP0000037163426.210413.0217caenorhabditis_elegansC36E6.1b.124.49312.1685
ENSG00000073792homo_sapiensENSP0000037163425.876512.02caenorhabditis_elegansM01A10.1.126.450512.2867
ENSG00000073792homo_sapiensENSP0000037163445.242127.5459caenorhabditis_elegansM88.5c.131.73319.3208
ENSG00000073792homo_sapiensENSP0000037163425.208713.6895drosophila_melanogasterFBpp029352126.352514.3106
ENSG00000073792homo_sapiensENSP0000037163422.704511.1853drosophila_melanogasterFBpp030641917.43598.58974
ENSG00000073792homo_sapiensENSP0000037163450.250434.3907drosophila_melanogasterFBpp029368047.178732.2884
ENSG00000073792homo_sapiensENSP0000037163420.868110.6845ciona_intestinalisENSCINP0000000198435.01417.9272
ENSG00000073792homo_sapiensENSP0000037163418.03018.01336ciona_intestinalisENSCINP0000002595038.028216.9014
ENSG00000073792homo_sapiensENSP0000037163460.934943.5726ciona_intestinalisENSCINP0000000872661.759744.1624
ENSG00000073792homo_sapiensENSP0000037163431.218727.379petromyzon_marinusENSPMAP0000000553678.571468.9076
ENSG00000073792homo_sapiensENSP0000037163478.964970.6177latimeria_chalumnaeENSLACP0000001311086.471777.3309
ENSG00000073792homo_sapiensENSP0000037163488.313979.2988lepisosteus_oculatusENSLOCP0000001169487.006678.125
ENSG00000073792homo_sapiensENSP0000037163472.120262.7713clupea_harengusENSCHAP0000005828275.261365.5052
ENSG00000073792homo_sapiensENSP0000037163458.096851.419danio_rerioENSDARP0000013975979.816570.6422
ENSG00000073792homo_sapiensENSP0000037163457.929948.7479carassius_auratusENSCARP0000002539777.111164.8889
ENSG00000073792homo_sapiensENSP0000037163461.936654.591carassius_auratusENSCARP0000002252078.2768.9873
ENSG00000073792homo_sapiensENSP0000037163484.474173.7896astyanax_mexicanusENSAMXP0000003557580.445270.2703
ENSG00000073792homo_sapiensENSP0000037163483.472572.788ictalurus_punctatusENSIPUP0000003295881.699371.2418
ENSG00000073792homo_sapiensENSP0000037163487.646178.798esox_luciusENSELUP0000007584786.490977.7595
ENSG00000073792homo_sapiensENSP0000037163452.587645.0751electrophorus_electricusENSEEEP0000001939478.7567.5
ENSG00000073792homo_sapiensENSP0000037163477.462468.4474oncorhynchus_kisutchENSOKIP0000500521377.333368.3333
ENSG00000073792homo_sapiensENSP0000037163474.624462.6043oncorhynchus_mykissENSOMYP0000011143847.301639.6825
ENSG00000073792homo_sapiensENSP0000037163410.85149.18197salmo_salarENSSSAP0000013763584.415671.4286
ENSG00000073792homo_sapiensENSP0000037163437.395723.0384salmo_salarENSSSAP0000013785542.666726.2857
ENSG00000073792homo_sapiensENSP0000037163483.973375.2922salmo_truttaENSSTUP0000002323084.113775.4181
ENSG00000073792homo_sapiensENSP0000037163477.796369.1152fundulus_heteroclitusENSFHEP0000000714384.727375.2727
ENSG00000073792homo_sapiensENSP0000037163488.814779.9666poecilia_reticulataENSPREP0000001394886.786378.1403
ENSG00000073792homo_sapiensENSP0000037163488.647779.4658xiphophorus_maculatusENSXMAP0000001555486.341577.3984
ENSG00000073792homo_sapiensENSP0000037163487.9878.4641oryzias_latipesENSORLP0000004362486.25276.9231
ENSG00000073792homo_sapiensENSP0000037163479.131969.1152cyclopterus_lumpusENSCLMP0000504319881.443371.134
ENSG00000073792homo_sapiensENSP0000037163488.647779.1319oreochromis_niloticusENSONIP0000001135586.906777.5777
ENSG00000073792homo_sapiensENSP0000037163488.814779.4658haplochromis_burtoniENSHBUP0000002268287.070477.9051
ENSG00000073792homo_sapiensENSP0000037163488.814779.4658astatotilapia_callipteraENSACLP0000002299087.070477.9051
ENSG00000073792homo_sapiensENSP0000037163485.475876.7947sparus_aurataENSSAUP0001006903183.934475.4098
ENSG00000073792homo_sapiensENSP0000037163485.976676.6277lates_calcariferENSLCAP0001005118386.264776.8844
ENSG00000073792homo_sapiensENSP0000037163493.155386.6444chrysemys_picta_belliiENSCPBP0000000952985.978479.9692
ENSG00000073792homo_sapiensENSP0000037163491.318984.6411sphenodon_punctatusENSSPUP0000002170889.967183.3882
ENSG00000073792homo_sapiensENSP0000037163492.320585.3088laticauda_laticaudataENSLLTP0000001330584.815978.3742
ENSG00000073792homo_sapiensENSP0000037163490.317283.9733notechis_scutatusENSNSUP0000001798393.923687.3264
ENSG00000073792homo_sapiensENSP0000037163492.320585.3088pseudonaja_textilisENSPTXP0000002728892.320585.3088
ENSG00000073792homo_sapiensENSP0000037163482.971676.9616anas_platyrhynchos_platyrhynchosENSAPLP0000000274188.7582.3214
ENSG00000073792homo_sapiensENSP0000037163492.988386.9783gallus_gallusENSGALP0001003695491.16285.2701
ENSG00000073792homo_sapiensENSP0000037163479.131971.1185meleagris_gallopavoENSMGAP0000002239077.198769.3811
ENSG00000073792homo_sapiensENSP0000037163482.136975.793serinus_canariaENSSCAP0000000749086.315879.6491
ENSG00000073792homo_sapiensENSP0000037163491.986686.1436parus_majorENSPMJP0000002234290.1884.4517
ENSG00000073792homo_sapiensENSP0000037163492.153684.6411anolis_carolinensisENSACAP0000000790467.564362.0563
ENSG00000073792homo_sapiensENSP0000037163486.644476.7947neolamprologus_brichardiENSNBRP0000002105886.789376.9231
ENSG00000073792homo_sapiensENSP0000037163491.986685.1419naja_najaENSNNAP0000002489091.986685.1419
ENSG00000073792homo_sapiensENSP0000037163493.489286.1436podarcis_muralisENSPMRP0000002213893.489286.1436
ENSG00000073792homo_sapiensENSP0000037163483.639476.6277geospiza_fortisENSGFOP0000002083587.130479.8261
ENSG00000073792homo_sapiensENSP0000037163492.153685.9766taeniopygia_guttataENSTGUP0000002391490.196184.1503
ENSG00000073792homo_sapiensENSP0000037163474.290564.9416erpetoichthys_calabaricusENSECRP0000001175981.056570.8561
ENSG00000073792homo_sapiensENSP0000037163486.811477.2955kryptolebias_marmoratusENSKMAP0000001635185.808676.4026
ENSG00000073792homo_sapiensENSP0000037163492.821485.4758salvator_merianaeENSSMRP0000002873992.821485.4758
ENSG00000073792homo_sapiensENSP0000037163485.809776.4608oryzias_javanicusENSOJAP0000004704085.809776.4608
ENSG00000073792homo_sapiensENSP0000037163483.639474.9583amphilophus_citrinellusENSACIP0000000160886.082577.1478
ENSG00000073792homo_sapiensENSP0000037163488.814779.9666dicentrarchus_labraxENSDLAP0000504874287.070478.3961
ENSG00000073792homo_sapiensENSP0000037163486.143676.4608amphiprion_perculaENSAPEP0000002260784.590275.082
ENSG00000073792homo_sapiensENSP0000037163487.81377.9633oryzias_sinensisENSOSIP0000001317286.088476.4321
ENSG00000073792homo_sapiensENSP0000037163448.080143.0718pelodiscus_sinensisENSPSIP0000001557992.903283.2258
ENSG00000073792homo_sapiensENSP0000037163493.155386.6444gopherus_evgoodeiENSGEVP000050250159386.5
ENSG00000073792homo_sapiensENSP0000037163480.634474.1235chelonoidis_abingdoniiENSCABP000000237989284.5714
ENSG00000073792homo_sapiensENSP0000037163488.647779.6327seriola_dumeriliENSSDUP0000002422986.906778.0687
ENSG00000073792homo_sapiensENSP0000037163487.479177.6294cottoperca_gobioENSCGOP0000005696686.75576.9868
ENSG00000073792homo_sapiensENSP0000037163478.130270.9516struthio_camelus_australisENSSCUP0000001983582.249674.6924
ENSG00000073792homo_sapiensENSP0000037163482.804776.6277anser_brachyrhynchusENSABRP0000002415689.692683.0018
ENSG00000073792homo_sapiensENSP0000037163487.9878.4641gasterosteus_aculeatusENSGACP0000000798586.111176.7974
ENSG00000073792homo_sapiensENSP0000037163485.976676.1269cynoglossus_semilaevisENSCSEP0000001826984.288174.6318
ENSG00000073792homo_sapiensENSP0000037163488.814779.9666poecilia_formosaENSPFOP0000000745986.64578.013
ENSG00000073792homo_sapiensENSP0000037163481.636172.2871myripristis_murdjanENSMMDP0000502588784.602174.9135
ENSG00000073792homo_sapiensENSP0000037163488.814779.6327sander_luciopercaENSSLUP0000005381187.070478.0687
ENSG00000073792homo_sapiensENSP0000037163492.821486.8114strigops_habroptilaENSSHBP0000501570490.849784.9673
ENSG00000073792homo_sapiensENSP0000037163482.136972.788amphiprion_ocellarisENSAOCP0000002769785.416775.6944
ENSG00000073792homo_sapiensENSP0000037163493.322286.8114terrapene_carolina_triunguisENSTMTP0000000186393.166786.6667
ENSG00000073792homo_sapiensENSP0000037163430.21726.8781hucho_huchoENSHHUP0000003873474.793466.5289
ENSG00000073792homo_sapiensENSP0000037163412.353910.8514hucho_huchoENSHHUP0000001740993.670982.2785
ENSG00000073792homo_sapiensENSP0000037163488.814779.6327betta_splendensENSBSLP0000001076985.945177.0598
ENSG00000073792homo_sapiensENSP0000037163484.97574.6244pygocentrus_nattereriENSPNAP0000002595083.993473.7624
ENSG00000073792homo_sapiensENSP0000037163488.814780.1336anabas_testudineusENSATEP0000002959987.070478.5597
ENSG00000073792homo_sapiensENSP0000037163416.86149.34892ciona_savignyiENSCSAVP0000000475548.095226.6667
ENSG00000073792homo_sapiensENSP000003716349.682814.8414ciona_savignyiENSCSAVP0000000721447.54123.7705
ENSG00000073792homo_sapiensENSP0000037163460.934943.0718ciona_savignyiENSCSAVP0000001881362.93144.4828
ENSG00000073792homo_sapiensENSP0000037163488.647779.6327seriola_lalandi_dorsalisENSSLDP0000000893286.906778.0687
ENSG00000073792homo_sapiensENSP0000037163411.686110.0167labrus_bergyltaENSLBEP0000003072788.607675.9494
ENSG00000073792homo_sapiensENSP0000037163461.936655.4257labrus_bergyltaENSLBEP0000000491183.747274.9436
ENSG00000073792homo_sapiensENSP0000037163484.97575.1252pundamilia_nyerereiENSPNYP0000000152684.833375
ENSG00000073792homo_sapiensENSP0000037163488.647779.9666mastacembelus_armatusENSMAMP0000000140286.906778.3961
ENSG00000073792homo_sapiensENSP0000037163411.85319.68281stegastes_partitusENSSPAP0000001226489.873473.4177
ENSG00000073792homo_sapiensENSP0000037163474.958368.4474stegastes_partitusENSSPAP0000000074884.082476.779
ENSG00000073792homo_sapiensENSP0000037163425.208722.3706oncorhynchus_tshawytschaENSOTSP0000508358286.781677.0115
ENSG00000073792homo_sapiensENSP0000037163412.353910.6845oncorhynchus_tshawytschaENSOTSP0000503787193.670981.0127
ENSG00000073792homo_sapiensENSP0000037163486.477576.6277acanthochromis_polyacanthusENSAPOP0000000263984.640575
ENSG00000073792homo_sapiensENSP0000037163492.487586.6444aquila_chrysaetos_chrysaetosENSACCP0002000795491.721985.9272
ENSG00000073792homo_sapiensENSP0000037163486.644477.7963nothobranchius_furzeriENSNFUP0001505344985.643676.8977
ENSG00000073792homo_sapiensENSP0000037163487.9878.798cyprinodon_variegatusENSCVAP0000002213386.25277.2504
ENSG00000073792homo_sapiensENSP0000037163483.639474.1235denticeps_clupeoidesENSDCDP0000000352482.401373.0263
ENSG00000073792homo_sapiensENSP0000037163487.646178.9649larimichthys_croceaENSLCRP0000502532685.924777.4141
ENSG00000073792homo_sapiensENSP0000037163485.809775.2922takifugu_rubripesENSTRUP0000008638184.678774.2998
ENSG00000073792homo_sapiensENSP0000037163480.968375.1252ficedula_albicollisENSFALP0000001392980.03374.2574
ENSG00000073792homo_sapiensENSP0000037163478.964969.4491hippocampus_comesENSHCOP0000001463685.843975.4991
ENSG00000073792homo_sapiensENSP0000037163462.604355.7596cyprinus_carpio_carpioENSCCRP0000005500778.781570.1681
ENSG00000073792homo_sapiensENSP0000037163457.095249.7496cyprinus_carpio_carpioENSCCRP0000015914678.620768.5057
ENSG00000073792homo_sapiensENSP0000037163492.988386.6444coturnix_japonicaENSCJPP0000502493692.833386.5
ENSG00000073792homo_sapiensENSP0000037163480.801371.6194poecilia_latipinnaENSPLAP0000002190686.428676.6071
ENSG00000073792homo_sapiensENSP0000037163463.272154.0901sinocyclocheilus_grahamiENSSGRP0000005046776.876365.7201
ENSG00000073792homo_sapiensENSP0000037163428.547624.5409sinocyclocheilus_grahamiENSSGRP0000009301677.02766.2162
ENSG00000073792homo_sapiensENSP0000037163454.924946.0768sinocyclocheilus_grahamiENSSGRP0000007287574.099162.1622
ENSG00000073792homo_sapiensENSP0000037163480.133671.7863maylandia_zebraENSMZEP0000501032385.714376.7857
ENSG00000073792homo_sapiensENSP0000037163484.641173.7896tetraodon_nigroviridisENSTNIP0000001957183.114872.459
ENSG00000073792homo_sapiensENSP0000037163487.312278.798paramormyrops_kingsleyaeENSPKIP0000002809385.457577.1242
ENSG00000073792homo_sapiensENSP0000037163487.145278.4641scleropages_formosusENSSFOP0001501207285.996777.43
ENSG00000073792homo_sapiensENSP0000037163486.477576.6277scophthalmus_maximusENSSMAP0000003811185.057575.3695
ENSG00000073792homo_sapiensENSP0000037163487.479177.7963oryzias_melastigmaENSOMEP0000000102182.131773.0407

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000932located_in P-body1IDAHomo_sapiens(9606)Component
GO:0001817involved_in regulation of cytokine production1ICHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003730enables mRNA 3-UTR binding2IBA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus2IBA,IDAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0005829is_active_in cytosol3IBA,IDA,TASHomo_sapiens(9606)Component
GO:0005856located_in cytoskeleton1IDAHomo_sapiens(9606)Component
GO:0007399involved_in nervous system development1IBAHomo_sapiens(9606)Process
GO:0009653involved_in anatomical structure morphogenesis1TASHomo_sapiens(9606)Process
GO:0010468involved_in regulation of gene expression1IBAHomo_sapiens(9606)Process
GO:0010494located_in cytoplasmic stress granule1IDAHomo_sapiens(9606)Component
GO:0017148involved_in negative regulation of translation1ISSHomo_sapiens(9606)Process
GO:0045182enables translation regulator activity1ISSHomo_sapiens(9606)Function
GO:0048027enables mRNA 5-UTR binding1IDAHomo_sapiens(9606)Function
GO:0051028involved_in mRNA transport1IEAHomo_sapiens(9606)Process
GO:0070934involved_in CRD-mediated mRNA stabilization1IDAHomo_sapiens(9606)Process
GO:0090079enables translation regulator activity, nucleic acid binding1IEAHomo_sapiens(9606)Function
GO:0097009involved_in energy homeostasis1IEAHomo_sapiens(9606)Process
GO:0106106involved_in cold-induced thermogenesis1IEAHomo_sapiens(9606)Process
GO:1990247enables N6-methyladenosine-containing RNA binding1IDAHomo_sapiens(9606)Function

Expression