Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerSARS-COV-2
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Metabolic enzyme
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000059573 Gene ID 5832 Accession 9722
Symbol ALDH18A1 Alias GSAS;P5CS;PYCS;SPG9;ADCL3;SPG9A;SPG9B;ARCL3A Full Name aldehyde dehydrogenase 18 family member A1
Status Confidence Length 50771 bases Strand Minus strand
Position 10 : 95605941 - 95656711 RNA binding domain N.A.
Summary This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
ALDH18A1-202 ENST00000371224 3352 795aa ENSP00000360268
ALDH18A1-201 ENST00000371221 3337 793aa ENSP00000360265
ALDH18A1-204 ENST00000485428 726 No protein -
ALDH18A1-205 ENST00000489386 543 No protein -
ALDH18A1-203 ENST00000483788 750 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
70655Metabolism8E-1124816252

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000059573

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000059573homo_sapiensENSP0000036026894.465493.4591nomascus_leucogenysENSNLEP0000001594996.158895.1344
ENSG00000059573homo_sapiensENSP00000360268100100pan_paniscusENSPPAP00000036745100100
ENSG00000059573homo_sapiensENSP0000036026899.622699.2453pongo_abeliiENSPPYP0000000291199.622699.2453
ENSG00000059573homo_sapiensENSP00000360268100100pan_troglodytesENSPTRP00000083069100100
ENSG00000059573homo_sapiensENSP0000036026899.748499.7484gorilla_gorillaENSGGOP0000001219099.748499.7484
ENSG00000059573homo_sapiensENSP0000036026894.968690.9434ornithorhynchus_anatinusENSOANP0000003464582.24478.7582
ENSG00000059573homo_sapiensENSP0000036026896.855392.956sarcophilus_harrisiiENSSHAP0000001328396.370592.4906
ENSG00000059573homo_sapiensENSP0000036026863.647861.8868notamacropus_eugeniiENSMEUP0000000315172.910770.8934
ENSG00000059573homo_sapiensENSP0000036026877.106975.5975choloepus_hoffmanniENSCHOP0000000530387.571485.8571
ENSG00000059573homo_sapiensENSP0000036026898.490697.3585dasypus_novemcinctusENSDNOP0000001384798.490697.3585
ENSG00000059573homo_sapiensENSP0000036026881.886880.6289erinaceus_europaeusENSEEUP0000001430388.571487.2109
ENSG00000059573homo_sapiensENSP0000036026860.628959.2453echinops_telfairiENSETEP0000000726975.19573.4789
ENSG00000059573homo_sapiensENSP0000036026899.371198.9937callithrix_jacchusENSCJAP0000007198997.530997.1605
ENSG00000059573homo_sapiensENSP0000036026897.735896.8553cercocebus_atysENSCATP0000004502996.641895.7711
ENSG00000059573homo_sapiensENSP0000036026895.094394.4654macaca_fascicularisENSMFAP0000004622599.604798.946
ENSG00000059573homo_sapiensENSP0000036026899.748499.1195macaca_mulattaENSMMUP0000000413999.748499.1195
ENSG00000059573homo_sapiensENSP0000036026898.867997.9874macaca_nemestrinaENSMNEP0000001946896.08895.2323
ENSG00000059573homo_sapiensENSP0000036026898.867998.239papio_anubisENSPANP0000002069496.08895.4768
ENSG00000059573homo_sapiensENSP0000036026893.081891.4465mandrillus_leucophaeusENSMLEP0000003326396.73295.0327
ENSG00000059573homo_sapiensENSP0000036026897.987496.1006tursiops_truncatusENSTTRP0000000305597.987496.1006
ENSG00000059573homo_sapiensENSP0000036026898.616496.9811vulpes_vulpesENSVVUP0000003137098.616496.9811
ENSG00000059573homo_sapiensENSP0000036026897.861695.4717mus_spretusMGP_SPRETEiJ_P005073997.861695.4717
ENSG00000059573homo_sapiensENSP0000036026898.490697.6101equus_asinusENSEASP0000501676398.490697.6101
ENSG00000059573homo_sapiensENSP0000036026898.23997.2327capra_hircusENSCHIP0000000514994.666793.697
ENSG00000059573homo_sapiensENSP0000036026898.364896.6038loxodonta_africanaENSLAFP0000001342498.364896.6038
ENSG00000059573homo_sapiensENSP0000036026898.23996.9811panthera_leoENSPLOP0000001615298.23996.9811
ENSG00000059573homo_sapiensENSP0000036026898.113296.8553ailuropoda_melanoleucaENSAMEP0000001689298.113296.8553
ENSG00000059573homo_sapiensENSP0000036026898.113297.1069bos_indicus_hybridENSBIXP0000502570498.113297.1069
ENSG00000059573homo_sapiensENSP0000036026898.490696.7296oryctolagus_cuniculusENSOCUP0000000515798.490696.7296
ENSG00000059573homo_sapiensENSP0000036026898.23997.3585equus_caballusENSECAP0000008124198.486897.604
ENSG00000059573homo_sapiensENSP0000036026898.490696.9811canis_lupus_familiarisENSCAFP0084503475298.120396.6165
ENSG00000059573homo_sapiensENSP0000036026898.490697.2327panthera_pardusENSPPRP0000000247998.490697.2327
ENSG00000059573homo_sapiensENSP0000036026898.742197.7358marmota_marmota_marmotaENSMMMP0000002428698.866597.8589
ENSG00000059573homo_sapiensENSP0000036026898.364896.7296balaenoptera_musculusENSBMSP0001002462198.364896.7296
ENSG00000059573homo_sapiensENSP0000036026897.987495.9748cavia_porcellusENSCPOP0000000015597.987495.9748
ENSG00000059573homo_sapiensENSP0000036026898.364897.1069felis_catusENSFCAP0000000132098.117996.8632
ENSG00000059573homo_sapiensENSP0000036026898.364897.2327ursus_americanusENSUAMP0000002804098.364897.2327
ENSG00000059573homo_sapiensENSP0000036026894.213888.1761monodelphis_domesticaENSMODP0000000616093.742287.7347
ENSG00000059573homo_sapiensENSP0000036026898.113297.1069bison_bison_bisonENSBBBP0000002649298.113297.1069
ENSG00000059573homo_sapiensENSP0000036026895.849194.4654monodon_monocerosENSMMNP0001502519599.607898.1699
ENSG00000059573homo_sapiensENSP0000036026898.616497.3585sus_scrofaENSSSCP0000001118298.616497.3585
ENSG00000059573homo_sapiensENSP0000036026898.616497.7358microcebus_murinusENSMICP0000004548698.616497.7358
ENSG00000059573homo_sapiensENSP0000036026897.232794.717octodon_degusENSODEP0000002146197.232794.717
ENSG00000059573homo_sapiensENSP0000036026898.23996.478jaculus_jaculusENSJJAP0000001224498.23996.478
ENSG00000059573homo_sapiensENSP0000036026898.23997.2327ovis_aries_rambouilletENSOARP0002002792598.23997.2327
ENSG00000059573homo_sapiensENSP0000036026898.616497.4843ursus_maritimusENSUMAP0000002944098.616497.4843
ENSG00000059573homo_sapiensENSP0000036026883.899482.5157ochotona_princepsENSOPRP0000000297984.00582.6196
ENSG00000059573homo_sapiensENSP0000036026898.23996.478delphinapterus_leucasENSDLEP0000002370698.23996.478
ENSG00000059573homo_sapiensENSP0000036026898.23996.478physeter_catodonENSPCTP0000503151098.23996.478
ENSG00000059573homo_sapiensENSP0000036026897.861695.4717mus_caroliMGP_CAROLIEiJ_P004873797.861695.4717
ENSG00000059573homo_sapiensENSP0000036026897.861695.4717mus_musculusENSMUSP0000002597997.861695.4717
ENSG00000059573homo_sapiensENSP0000036026886.792483.7736dipodomys_ordiiENSDORP0000001325991.755388.5638
ENSG00000059573homo_sapiensENSP0000036026898.113296.6038mustela_putorius_furoENSMPUP0000001700598.113296.6038
ENSG00000059573homo_sapiensENSP0000036026899.245398.8679aotus_nancymaaeENSANAP0000002771099.245398.8679
ENSG00000059573homo_sapiensENSP0000036026899.496999.1195saimiri_boliviensis_boliviensisENSSBOP0000000808999.496999.1195
ENSG00000059573homo_sapiensENSP0000036026852.075551.6981vicugna_pacosENSVPAP0000000252582.142981.5476
ENSG00000059573homo_sapiensENSP0000036026861.76161.3836chlorocebus_sabaeusENSCSAP0000000244999.191998.5859
ENSG00000059573homo_sapiensENSP0000036026890.691889.434tupaia_belangeriENSTBEP0000000880391.497590.2284
ENSG00000059573homo_sapiensENSP0000036026897.735895.2201mesocricetus_auratusENSMAUP0000002357797.735895.2201
ENSG00000059573homo_sapiensENSP0000036026893.962391.0692phocoena_sinusENSPSNP0000002165090.545587.7576
ENSG00000059573homo_sapiensENSP0000036026898.23996.9811camelus_dromedariusENSCDRP0000501622598.23996.9811
ENSG00000059573homo_sapiensENSP0000036026898.23997.2327carlito_syrichtaENSTSYP0000002250998.23997.2327
ENSG00000059573homo_sapiensENSP0000036026898.364897.1069panthera_tigris_altaicaENSPTIP0000002667298.364897.1069
ENSG00000059573homo_sapiensENSP0000036026896.981194.717rattus_norvegicusENSRNOP0000008984797.471695.196
ENSG00000059573homo_sapiensENSP0000036026898.364897.3585prolemur_simusENSPSMP0000001555498.364897.3585
ENSG00000059573homo_sapiensENSP0000036026897.861695.3459microtus_ochrogasterENSMOCP0000001456397.861695.3459
ENSG00000059573homo_sapiensENSP0000036026881.006378.4906sorex_araneusENSSARP0000000111881.622379.0875
ENSG00000059573homo_sapiensENSP0000036026897.861695.3459peromyscus_maniculatus_bairdiiENSPEMP0000001286597.861695.3459
ENSG00000059573homo_sapiensENSP0000036026898.113296.9811bos_mutusENSBMUP0000002702598.113296.9811
ENSG00000059573homo_sapiensENSP0000036026897.735895.4717mus_spicilegusENSMSIP0000000641597.735895.4717
ENSG00000059573homo_sapiensENSP0000036026897.735895.3459cricetulus_griseus_chok1gshdENSCGRP0000102192397.735895.3459
ENSG00000059573homo_sapiensENSP0000036026874.968673.8365pteropus_vampyrusENSPVAP0000000856574.968673.8365
ENSG00000059573homo_sapiensENSP0000036026897.232795.4717myotis_lucifugusENSMLUP0000001005096.867295.1128
ENSG00000059573homo_sapiensENSP0000036026896.100692.956vombatus_ursinusENSVURP0001000130395.380892.2597
ENSG00000059573homo_sapiensENSP0000036026897.861696.2264rhinolophus_ferrumequinumENSRFEP0001002449097.861696.2264
ENSG00000059573homo_sapiensENSP0000036026898.113296.7296neovison_visonENSNVIP0000000045898.113296.7296
ENSG00000059573homo_sapiensENSP0000036026898.113297.1069bos_taurusENSBTAP0000001570398.113297.1069
ENSG00000059573homo_sapiensENSP0000036026898.23996.6038heterocephalus_glaber_femaleENSHGLP0000005879898.23996.6038
ENSG00000059573homo_sapiensENSP0000036026899.748499.3711rhinopithecus_bietiENSRBIP0000000476899.748499.3711
ENSG00000059573homo_sapiensENSP0000036026898.616497.1069canis_lupus_dingoENSCAFP0002000675198.616497.1069
ENSG00000059573homo_sapiensENSP0000036026898.364897.2327sciurus_vulgarisENSSVLP0000502938298.488797.3552
ENSG00000059573homo_sapiensENSP0000036026896.226492.4528phascolarctos_cinereusENSPCIP0000002748795.505691.7603
ENSG00000059573homo_sapiensENSP0000036026898.113295.9748procavia_capensisENSPCAP0000000163298.113295.9748
ENSG00000059573homo_sapiensENSP0000036026898.113295.5975nannospalax_galiliENSNGAP0000000949298.113295.5975
ENSG00000059573homo_sapiensENSP0000036026898.23997.1069bos_grunniensENSBGRP0000004082098.23997.1069
ENSG00000059573homo_sapiensENSP0000036026898.113296.3522chinchilla_lanigeraENSCLAP0000000254398.113296.3522
ENSG00000059573homo_sapiensENSP0000036026898.364897.3585cervus_hanglu_yarkandensisENSCHYP0000002065198.364897.3585
ENSG00000059573homo_sapiensENSP0000036026898.364896.7296catagonus_wagneriENSCWAP0000002354298.612996.9735
ENSG00000059573homo_sapiensENSP0000036026887.924586.9182ictidomys_tridecemlineatusENSSTOP0000000711198.589697.4612
ENSG00000059573homo_sapiensENSP0000036026898.867997.6101otolemur_garnettiiENSOGAP0000000333698.867997.6101
ENSG00000059573homo_sapiensENSP0000036026899.245398.7421cebus_imitatorENSCCAP0000001019199.245398.7421
ENSG00000059573homo_sapiensENSP0000036026898.616497.4843urocitellus_parryiiENSUPAP0001001726298.740697.6071
ENSG00000059573homo_sapiensENSP0000036026898.113297.1069moschus_moschiferusENSMMSP0000003100198.113297.1069
ENSG00000059573homo_sapiensENSP0000036026899.622699.2453rhinopithecus_roxellanaENSRROP0000002816899.622699.2453
ENSG00000059573homo_sapiensENSP0000036026897.861695.4717mus_pahariMGP_PahariEiJ_P002170097.861695.4717
ENSG00000059573homo_sapiensENSP0000036026898.616497.6101propithecus_coquereliENSPCOP0000002088498.616497.6101
ENSG00000059573homo_sapiensENSP0000036026867.295651.3208caenorhabditis_elegansT22H6.2b.166.708250.8728
ENSG00000059573homo_sapiensENSP0000036026870.691855.5975drosophila_melanogasterFBpp030160372.422756.9588
ENSG00000059573homo_sapiensENSP0000036026867.421451.0692ciona_intestinalisENSCINP0000000525173.324255.5404
ENSG00000059573homo_sapiensENSP0000036026863.144750.3145eptatretus_burgeriENSEBUP0000000052076.524460.9756
ENSG00000059573homo_sapiensENSP0000036026889.559780.2516callorhinchus_miliiENSCMIP0000002968289.111479.8498
ENSG00000059573homo_sapiensENSP0000036026891.069283.0189latimeria_chalumnaeENSLACP0000001263390.954882.9146
ENSG00000059573homo_sapiensENSP0000036026891.19582.5157lepisosteus_oculatusENSLOCP0000001498192.71183.8875
ENSG00000059573homo_sapiensENSP0000036026870.188761.8868clupea_harengusENSCHAP0000001000771.173562.7551
ENSG00000059573homo_sapiensENSP0000036026888.930879.6226clupea_harengusENSCHAP0000000955989.493780.1266
ENSG00000059573homo_sapiensENSP0000036026889.308281.0063danio_rerioENSDARP0000013716290.792882.3529
ENSG00000059573homo_sapiensENSP0000036026889.182480.8805carassius_auratusENSCARP0000011594988.958680.6775
ENSG00000059573homo_sapiensENSP0000036026889.559780.8805carassius_auratusENSCARP0000007668188.778180.1746
ENSG00000059573homo_sapiensENSP0000036026889.43480.6289astyanax_mexicanusENSAMXP0000001337291.153882.1795
ENSG00000059573homo_sapiensENSP0000036026888.050379.3711ictalurus_punctatusENSIPUP0000002395184.541176.2077
ENSG00000059573homo_sapiensENSP0000036026887.169877.7358esox_luciusENSELUP0000007611584.926575.7353
ENSG00000059573homo_sapiensENSP0000036026886.792476.9811esox_luciusENSELUP0000007645384.455374.9082
ENSG00000059573homo_sapiensENSP0000036026889.937180.8805electrophorus_electricusENSEEEP0000000851587.622678.799
ENSG00000059573homo_sapiensENSP0000036026888.176179.1195oncorhynchus_kisutchENSOKIP0000503207286.972778.0397
ENSG00000059573homo_sapiensENSP0000036026887.547276.9811oncorhynchus_kisutchENSOKIP0000501546986.032175.6489
ENSG00000059573homo_sapiensENSP0000036026889.559780.3774oncorhynchus_kisutchENSOKIP0000507331189.33580.1757
ENSG00000059573homo_sapiensENSP0000036026888.427778.9937oncorhynchus_mykissENSOMYP0000002409185.941376.7726
ENSG00000059573homo_sapiensENSP0000036026889.559780.3774oncorhynchus_mykissENSOMYP0000003779890.700681.4013
ENSG00000059573homo_sapiensENSP0000036026887.04477.3585oncorhynchus_mykissENSOMYP0000008133984.184974.8175
ENSG00000059573homo_sapiensENSP0000036026887.798778.6164salmo_salarENSSSAP0000009343484.606175.7576
ENSG00000059573homo_sapiensENSP0000036026888.80579.3711salmo_salarENSSSAP0000010873086.838977.6138
ENSG00000059573homo_sapiensENSP0000036026889.308280salmo_salarENSSSAP0000005651590.445981.0191
ENSG00000059573homo_sapiensENSP0000036026889.308280salmo_truttaENSSTUP0000003286690.445981.0191
ENSG00000059573homo_sapiensENSP0000036026887.798778.6164salmo_truttaENSSTUP0000007056883.194374.4934
ENSG00000059573homo_sapiensENSP0000036026888.679279.2453salmo_truttaENSSTUP0000002387486.291377.1114
ENSG00000059573homo_sapiensENSP0000036026843.899439.8742gadus_morhuaENSGMOP0000002775989.258381.0742
ENSG00000059573homo_sapiensENSP0000036026888.176178.3648gadus_morhuaENSGMOP0000003508187.62577.875
ENSG00000059573homo_sapiensENSP0000036026845.534637.9874gadus_morhuaENSGMOP0000004997486.396272.0764
ENSG00000059573homo_sapiensENSP0000036026883.144772.327fundulus_heteroclitusENSFHEP0000001416687.318475.9577
ENSG00000059573homo_sapiensENSP0000036026889.43480.2516fundulus_heteroclitusENSFHEP0000003022891.505882.1107
ENSG00000059573homo_sapiensENSP0000036026890.062980.3774poecilia_reticulataENSPREP0000001351691.912782.0282
ENSG00000059573homo_sapiensENSP0000036026886.163574.9686poecilia_reticulataENSPREP0000000084388.96177.4026
ENSG00000059573homo_sapiensENSP0000036026883.899472.7044xiphophorus_maculatusENSXMAP0000001471784.00572.796
ENSG00000059573homo_sapiensENSP0000036026890.062980xiphophorus_maculatusENSXMAP0000004148091.912781.6431
ENSG00000059573homo_sapiensENSP0000036026884.150973.7107oryzias_latipesENSORLP0000001049891.144479.8365
ENSG00000059573homo_sapiensENSP0000036026889.182480.7547oryzias_latipesENSORLP0000001653790.66582.0972
ENSG00000059573homo_sapiensENSP0000036026887.924579.7484cyclopterus_lumpusENSCLMP0000502155088.146379.9496
ENSG00000059573homo_sapiensENSP0000036026887.924578.239cyclopterus_lumpusENSCLMP0000501345386.083776.601
ENSG00000059573homo_sapiensENSP0000036026887.295677.1069oreochromis_niloticusENSONIP0000003378988.18377.8907
ENSG00000059573homo_sapiensENSP0000036026889.43479.7484oreochromis_niloticusENSONIP0000006970690.573280.7643
ENSG00000059573homo_sapiensENSP0000036026890.062980.7547haplochromis_burtoniENSHBUP0000002728591.912782.4134
ENSG00000059573homo_sapiensENSP0000036026887.421476.6038haplochromis_burtoniENSHBUP0000001402988.874777.8772
ENSG00000059573homo_sapiensENSP0000036026890.188780.7547astatotilapia_callipteraENSACLP0000003279792.041182.4134
ENSG00000059573homo_sapiensENSP0000036026887.295676.6038astatotilapia_callipteraENSACLP0000001160588.746877.8772
ENSG00000059573homo_sapiensENSP0000036026889.937180sparus_aurataENSSAUP0001004300991.902381.7481
ENSG00000059573homo_sapiensENSP0000036026888.679278.239sparus_aurataENSSAUP0001005945788.567878.1407
ENSG00000059573homo_sapiensENSP0000036026889.182480.8805lates_calcariferENSLCAP0001000812787.747579.5792
ENSG00000059573homo_sapiensENSP0000036026884.402574.4654lates_calcariferENSLCAP0001000232282.839573.0864
ENSG00000059573homo_sapiensENSP0000036026893.710787.2956xenopus_tropicalisENSXETP0000007351589.543383.4135
ENSG00000059573homo_sapiensENSP0000036026889.182484.5283chrysemys_picta_belliiENSCPBP0000001685193.535688.6544
ENSG00000059573homo_sapiensENSP0000036026894.339689.0566sphenodon_punctatusENSSPUP0000002017793.399788.1694
ENSG00000059573homo_sapiensENSP0000036026889.308284.2767laticauda_laticaudataENSLLTP0000002512593.544188.274
ENSG00000059573homo_sapiensENSP0000036026894.213889.5597notechis_scutatusENSNSUP0000001470694.213889.5597
ENSG00000059573homo_sapiensENSP0000036026895.345990.3145pseudonaja_textilisENSPTXP0000002598194.868689.8623
ENSG00000059573homo_sapiensENSP0000036026895.597589.1824anas_platyrhynchos_platyrhynchosENSAPLP0000000595794.763188.404
ENSG00000059573homo_sapiensENSP0000036026895.220189.5597gallus_gallusENSGALP0001000219192.092586.618
ENSG00000059573homo_sapiensENSP0000036026895.345989.1824meleagris_gallopavoENSMGAP0000001251494.513788.404
ENSG00000059573homo_sapiensENSP0000036026894.968689.3082serinus_canariaENSSCAP0000001342794.493188.8611
ENSG00000059573homo_sapiensENSP0000036026895.094389.8113parus_majorENSPMJP0000000743894.264389.0274
ENSG00000059573homo_sapiensENSP0000036026894.465488.805anolis_carolinensisENSACAP0000003060693.757888.1398
ENSG00000059573homo_sapiensENSP0000036026886.415176.2264neolamprologus_brichardiENSNBRP0000002118191.680.8
ENSG00000059573homo_sapiensENSP0000036026890.314580.5031neolamprologus_brichardiENSNBRP0000002039092.169482.1566
ENSG00000059573homo_sapiensENSP0000036026888.427783.7736naja_najaENSNNAP0000001132592.989488.0952
ENSG00000059573homo_sapiensENSP0000036026890.062985.5346podarcis_muralisENSPMRP0000000500994.459189.7098
ENSG00000059573homo_sapiensENSP0000036026893.584987.673geospiza_fortisENSGFOP0000001898993.233187.3434
ENSG00000059573homo_sapiensENSP0000036026895.220189.3082taeniopygia_guttataENSTGUP0000001206258.275654.6574
ENSG00000059573homo_sapiensENSP0000036026890.817683.8994erpetoichthys_calabaricusENSECRP0000000518092.445685.4033
ENSG00000059573homo_sapiensENSP0000036026886.540976.1006kryptolebias_marmoratusENSKMAP0000002303289.119278.3679
ENSG00000059573homo_sapiensENSP0000036026889.559780.1258kryptolebias_marmoratusENSKMAP0000001265291.399281.7715
ENSG00000059573homo_sapiensENSP0000036026895.220189.434salvator_merianaeENSSMRP0000002857394.743488.9862
ENSG00000059573homo_sapiensENSP0000036026888.176179.2453oryzias_javanicusENSOJAP0000000923089.987280.8729
ENSG00000059573homo_sapiensENSP0000036026886.037774.4654oryzias_javanicusENSOJAP0000002075884.548873.1768
ENSG00000059573homo_sapiensENSP0000036026888.301979.7484amphilophus_citrinellusENSACIP0000000618992.980183.9735
ENSG00000059573homo_sapiensENSP0000036026888.553579.8742amphilophus_citrinellusENSACIP0000000629191.073782.1475
ENSG00000059573homo_sapiensENSP0000036026887.547276.8553amphilophus_citrinellusENSACIP0000003167491.099579.9738
ENSG00000059573homo_sapiensENSP0000036026887.295677.2327dicentrarchus_labraxENSDLAP0000502571786.858676.8461
ENSG00000059573homo_sapiensENSP0000036026889.811380.7547dicentrarchus_labraxENSDLAP0000505430092.010382.732
ENSG00000059573homo_sapiensENSP0000036026888.176177.6101amphiprion_perculaENSAPEP0000002099989.871879.1026
ENSG00000059573homo_sapiensENSP0000036026889.559779.7484amphiprion_perculaENSAPEP0000003449491.516781.491
ENSG00000059573homo_sapiensENSP0000036026886.037777.7358oryzias_sinensisENSOSIP0000002674390.836782.0717
ENSG00000059573homo_sapiensENSP0000036026885.534674.4654oryzias_sinensisENSOSIP0000003409784.47273.5404
ENSG00000059573homo_sapiensENSP0000036026895.471790.3145pelodiscus_sinensisENSPSIP0000001235794.638489.5262
ENSG00000059573homo_sapiensENSP0000036026895.345989.9371chelonoidis_abingdoniiENSCABP0000001122394.044788.7097
ENSG00000059573homo_sapiensENSP0000036026889.559780.1258seriola_dumeriliENSSDUP0000000588691.399281.7715
ENSG00000059573homo_sapiensENSP0000036026889.182478.7421seriola_dumeriliENSSDUP0000002928588.514478.1523
ENSG00000059573homo_sapiensENSP0000036026883.647872.7044cottoperca_gobioENSCGOP0000001016987.730976.2533
ENSG00000059573homo_sapiensENSP0000036026889.685579.6226cottoperca_gobioENSCGOP0000004226991.881481.5722
ENSG00000059573homo_sapiensENSP0000036026891.320885.283struthio_camelus_australisENSSCUP0000001051491.782685.7143
ENSG00000059573homo_sapiensENSP0000036026895.597589.5597anser_brachyrhynchusENSABRP0000001079294.763188.7781
ENSG00000059573homo_sapiensENSP0000036026886.540975.9748gasterosteus_aculeatusENSGACP0000000794889.119278.2383
ENSG00000059573homo_sapiensENSP0000036026889.182480.2516gasterosteus_aculeatusENSGACP0000000448791.36682.2165
ENSG00000059573homo_sapiensENSP0000036026888.80579.2453cynoglossus_semilaevisENSCSEP0000001972090.62980.8729
ENSG00000059573homo_sapiensENSP0000036026887.421476.1006poecilia_formosaENSPFOP0000000200788.53577.0701
ENSG00000059573homo_sapiensENSP0000036026889.937180.2516poecilia_formosaENSPFOP0000003098991.784381.8999
ENSG00000059573homo_sapiensENSP0000036026890.440381.1321myripristis_murdjanENSMMDP0000505431392.535483.0116
ENSG00000059573homo_sapiensENSP0000036026888.427778.4906myripristis_murdjanENSMMDP0000505336988.095278.1955
ENSG00000059573homo_sapiensENSP0000036026889.182480.3774sander_luciopercaENSSLUP0000003949291.248482.2394
ENSG00000059573homo_sapiensENSP0000036026887.547277.8616sander_luciopercaENSSLUP0000003334387.989978.2554
ENSG00000059573homo_sapiensENSP0000036026895.220189.5597strigops_habroptilaENSSHBP0000500034494.62589
ENSG00000059573homo_sapiensENSP0000036026889.811380.1258amphiprion_ocellarisENSAOCP0000000921891.773881.8766
ENSG00000059573homo_sapiensENSP0000036026886.289376.3522amphiprion_ocellarisENSAOCP0000002026293.080182.3609
ENSG00000059573homo_sapiensENSP0000036026895.471790.4403terrapene_carolina_triunguisENSTMTP0000000927994.638489.6509
ENSG00000059573homo_sapiensENSP0000036026818.113215.8491hucho_huchoENSHHUP0000006432783.720973.2558
ENSG00000059573homo_sapiensENSP0000036026861.635253.9623hucho_huchoENSHHUP0000005416789.416178.2847
ENSG00000059573homo_sapiensENSP0000036026889.559780.5031hucho_huchoENSHHUP0000004778391.282182.0513
ENSG00000059573homo_sapiensENSP0000036026888.050378.1132hucho_huchoENSHHUP0000008965789.058579.0076
ENSG00000059573homo_sapiensENSP0000036026886.792476.478betta_splendensENSBSLP0000005565085.501975.3408
ENSG00000059573homo_sapiensENSP0000036026888.679279.4969betta_splendensENSBSLP0000004382386.185877.2616
ENSG00000059573homo_sapiensENSP0000036026889.056680.3774pygocentrus_nattereriENSPNAP0000002093290.537181.7136
ENSG00000059573homo_sapiensENSP0000036026887.798777.2327anabas_testudineusENSATEP0000005176288.354477.7215
ENSG00000059573homo_sapiensENSP0000036026889.056679.7484anabas_testudineusENSATEP0000001986290.885781.3864
ENSG00000059573homo_sapiensENSP0000036026826.666716.3522saccharomyces_cerevisiaeYHR033W50.118230.7329
ENSG00000059573homo_sapiensENSP0000036026826.540916.8553saccharomyces_cerevisiaeYDR300C49.299131.3084
ENSG00000059573homo_sapiensENSP0000036026889.559779.8742seriola_lalandi_dorsalisENSSLDP0000003109291.399281.5148
ENSG00000059573homo_sapiensENSP0000036026888.427778.239seriola_lalandi_dorsalisENSSLDP0000002520089.897779.5396
ENSG00000059573homo_sapiensENSP0000036026889.182479.7484labrus_bergyltaENSLBEP0000001561091.014181.3864
ENSG00000059573homo_sapiensENSP0000036026887.169877.3585labrus_bergyltaENSLBEP0000001292488.392978.4439
ENSG00000059573homo_sapiensENSP0000036026890.314580.6289pundamilia_nyerereiENSPNYP0000001715492.169482.285
ENSG00000059573homo_sapiensENSP0000036026884.779974.8428pundamilia_nyerereiENSPNYP0000002562593.351882.41
ENSG00000059573homo_sapiensENSP0000036026887.169876.1006mastacembelus_armatusENSMAMP0000004780588.846277.5641
ENSG00000059573homo_sapiensENSP0000036026888.930879.6226mastacembelus_armatusENSMAMP0000002423890.64181.1538
ENSG00000059573homo_sapiensENSP0000036026890.062980.6289stegastes_partitusENSSPAP0000000802191.912782.285
ENSG00000059573homo_sapiensENSP0000036026887.295676.8553stegastes_partitusENSSPAP0000002808192.410181.3582
ENSG00000059573homo_sapiensENSP0000036026886.918276.6038oncorhynchus_tshawytschaENSOTSP0000508137286.159675.9352
ENSG00000059573homo_sapiensENSP0000036026889.43480.3774oncorhynchus_tshawytschaENSOTSP0000507907989.43480.3774
ENSG00000059573homo_sapiensENSP0000036026888.80579.3711oncorhynchus_tshawytschaENSOTSP0000501006484.147875.2086
ENSG00000059573homo_sapiensENSP0000036026887.924579.4969acanthochromis_polyacanthusENSAPOP0000003321187.924579.4969
ENSG00000059573homo_sapiensENSP0000036026888.050377.8616acanthochromis_polyacanthusENSAPOP0000003210289.743679.359
ENSG00000059573homo_sapiensENSP0000036026895.345989.8113aquila_chrysaetos_chrysaetosENSACCP0002000782794.513789.0274
ENSG00000059573homo_sapiensENSP0000036026886.666776.9811nothobranchius_furzeriENSNFUP0001503367658.439451.9084
ENSG00000059573homo_sapiensENSP0000036026887.798774.4654nothobranchius_furzeriENSNFUP0001505211888.131374.7475
ENSG00000059573homo_sapiensENSP0000036026890.062980.7547cyprinodon_variegatusENSCVAP0000002964091.912782.4134
ENSG00000059573homo_sapiensENSP0000036026885.534673.4591cyprinodon_variegatusENSCVAP0000000617189.947177.2487
ENSG00000059573homo_sapiensENSP0000036026889.811380.2516denticeps_clupeoidesENSDCDP0000001955787.578.1863
ENSG00000059573homo_sapiensENSP0000036026887.67377.8616larimichthys_croceaENSLCRP0000505971385.521575.9509
ENSG00000059573homo_sapiensENSP0000036026888.427779.8742larimichthys_croceaENSLCRP0000506487089.326680.6861
ENSG00000059573homo_sapiensENSP0000036026886.918276.8553takifugu_rubripesENSTRUP0000004838184.577774.7858
ENSG00000059573homo_sapiensENSP0000036026887.67378.239takifugu_rubripesENSTRUP0000008258486.262476.9802
ENSG00000059573homo_sapiensENSP0000036026894.968689.434ficedula_albicollisENSFALP0000003422460.642657.1084
ENSG00000059573homo_sapiensENSP0000036026889.685580.7547hippocampus_comesENSHCOP0000001879391.527682.4134
ENSG00000059573homo_sapiensENSP0000036026884.276770.3145hippocampus_comesENSHCOP0000001284581.907168.3374
ENSG00000059573homo_sapiensENSP0000036026889.43481.1321cyprinus_carpio_carpioENSCCRP0000004047288.32380.1242
ENSG00000059573homo_sapiensENSP0000036026889.937181.2579cyprinus_carpio_carpioENSCCRP0000016446285.017876.8133
ENSG00000059573homo_sapiensENSP0000036026894.71789.0566coturnix_japonicaENSCJPP0000500423393.890388.2793
ENSG00000059573homo_sapiensENSP0000036026889.937180.3774poecilia_latipinnaENSPLAP0000002244191.784382.0282
ENSG00000059573homo_sapiensENSP0000036026886.792475.5975poecilia_latipinnaENSPLAP0000001324587.011475.7881
ENSG00000059573homo_sapiensENSP0000036026876.226468.6792sinocyclocheilus_grahamiENSSGRP0000001630889.248980.4124
ENSG00000059573homo_sapiensENSP0000036026889.685580.6289sinocyclocheilus_grahamiENSSGRP0000003747888.461579.5285
ENSG00000059573homo_sapiensENSP0000036026884.654174.717maylandia_zebraENSMZEP0000502103393.213382.2715
ENSG00000059573homo_sapiensENSP0000036026890.188780.7547maylandia_zebraENSMZEP0000501410792.041182.4134
ENSG00000059573homo_sapiensENSP0000036026886.289375.8491tetraodon_nigroviridisENSTNIP0000000679389.908379.0301
ENSG00000059573homo_sapiensENSP0000036026887.924578.9937tetraodon_nigroviridisENSTNIP0000001641087.703978.7955
ENSG00000059573homo_sapiensENSP0000036026864.528357.6101paramormyrops_kingsleyaeENSPKIP0000001444784.51475.453
ENSG00000059573homo_sapiensENSP0000036026889.43480.2516paramormyrops_kingsleyaeENSPKIP0000002039990.228480.9645
ENSG00000059573homo_sapiensENSP0000036026887.295677.2327scleropages_formosusENSSFOP0001503277678.953469.8521
ENSG00000059573homo_sapiensENSP0000036026890.314580.6289scleropages_formosusENSSFOP0001504452586.924977.6029
ENSG00000059573homo_sapiensENSP0000036026894.213887.9245leptobrachium_leishanenseENSLLEP0000002598086.89181.0905
ENSG00000059573homo_sapiensENSP0000036026888.301979.4969scophthalmus_maximusENSSMAP0000005928988.636479.798
ENSG00000059573homo_sapiensENSP0000036026888.553578.239scophthalmus_maximusENSSMAP0000006333287.236777.0756
ENSG00000059573homo_sapiensENSP0000036026889.43480.8805oryzias_melastigmaENSOMEP0000001641691.270982.5417
ENSG00000059573homo_sapiensENSP0000036026886.037774.4654oryzias_melastigmaENSOMEP0000003048788.372176.4858

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0004349enables glutamate 5-kinase activity2IDA,IMPHomo_sapiens(9606)Function
GO:0004350enables glutamate-5-semialdehyde dehydrogenase activity3IBA,IDA,IMPHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IEAHomo_sapiens(9606)Function
GO:0005739is_active_in mitochondrion2IBA,IDAHomo_sapiens(9606)Component
GO:0005743located_in mitochondrial inner membrane1TASHomo_sapiens(9606)Component
GO:0006536involved_in glutamate metabolic process1IMPHomo_sapiens(9606)Process
GO:0006561involved_in proline biosynthetic process1IMPHomo_sapiens(9606)Process
GO:0006592involved_in ornithine biosynthetic process1IMPHomo_sapiens(9606)Process
GO:0009266involved_in response to temperature stimulus1IEAHomo_sapiens(9606)Process
GO:0016310involved_in phosphorylation1IEAHomo_sapiens(9606)Process
GO:0019240involved_in citrulline biosynthetic process1IMPHomo_sapiens(9606)Process
GO:0042802enables identical protein binding1IDAHomo_sapiens(9606)Function
GO:0055129involved_in L-proline biosynthetic process1IEAHomo_sapiens(9606)Process

Expression